Drosophila melanogaster

62 known processes

Cul-2 (Dmel_CG1512)

Cullin-2

(Aliases: CG1512,DMcul-2,Dmel\CG1512,CUL2,l(2)02074,cul-2,Cul2)

Cul-2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
germarium derived egg chamber formationGO:00072931010.921
regulation of transportGO:00510491810.838
meiotic cell cycleGO:00513211710.810
dendrite developmentGO:00163582040.760
regulation of synapse organizationGO:00508071100.745
meiotic nuclear divisionGO:00071261510.679
neuromuscular junction developmentGO:00075281490.626
regulation of synapse assemblyGO:0051963940.566
regulation of cell cycleGO:00517262910.556
negative regulation of cell cycleGO:00457861160.550
establishment of localization in cellGO:00516494020.547
organic substance transportGO:00717022570.543
regulation of synapse structure and activityGO:00508031280.540
maintenance of protein location in cellGO:0032507260.517
regulation of synaptic growth at neuromuscular junctionGO:0008582890.516
regulation of nucleocytoplasmic transportGO:0046822350.481
regulation of growthGO:00400082330.470
dendrite morphogenesisGO:00488131990.445
negative regulation of cell cycle phase transitionGO:19019881030.429
cellular macromolecule localizationGO:00707272200.427
female meiotic divisionGO:0007143700.414
protein transportGO:00150311550.409
germarium derived female germ line cyst formationGO:0030727420.403
regulation of intracellular transportGO:0032386640.332
synapse assemblyGO:00074161430.323
regulation of mitotic cell cycle phase transitionGO:19019901300.319
cell cycle checkpointGO:0000075950.307
growthGO:00400073590.295
regulation of intracellular protein transportGO:0033157460.290
regulation of organelle organizationGO:00330431960.279
regulation of cytoplasmic transportGO:1903649470.257
intracellular signal transductionGO:00355563000.256
nuclear divisionGO:00002803320.252
regulation of phosphate metabolic processGO:00192202100.246
negative regulation of multicellular organismal processGO:00512411420.245
cellular nitrogen compound catabolic processGO:00442701650.241
regulation of dendrite developmentGO:0050773370.225
renal system developmentGO:0072001720.225
developmental growthGO:00485892800.215
regulation of cell cycle phase transitionGO:19019871300.208
single organism behaviorGO:00447083910.208
chromosome organizationGO:00512763600.207
endocytosisGO:00068973100.206
kidney developmentGO:000182230.205
synapse organizationGO:00508081960.198
protein import into nucleusGO:0006606510.196
regulation of mitotic cell cycleGO:00073461900.195
membrane disassemblyGO:003039740.193
phosphorylationGO:00163102940.192
positive regulation of cellular component organizationGO:00511301560.189
single organism nuclear importGO:1902593510.188
intracellular transportGO:00469072280.185
intracellular protein transportGO:00068861040.181
axon developmentGO:00615642970.178
regulation of protein transportGO:0051223570.171
vesicle mediated transportGO:00161923810.170
establishment of protein localizationGO:00451841630.168
regulation of establishment of protein localizationGO:0070201610.168
protein localization to nucleusGO:0034504550.160
regulation of cellular component biogenesisGO:00440872010.160
homeostatic processGO:00425921990.159
learning or memoryGO:00076111410.155
protein importGO:0017038550.154
cellular protein catabolic processGO:0044257830.144
phagocytosisGO:00069092150.141
negative regulation of mitotic cell cycle phase transitionGO:19019911030.141
response to abiotic stimulusGO:00096283410.140
cell divisionGO:00513012480.138
synaptic growth at neuromuscular junctionGO:00511241190.130
regulation of developmental growthGO:00486381740.128
regulation of meiosisGO:004002030.128
regulation of protein metabolic processGO:00512462560.124
female germline ring canal formationGO:000730190.123
ion transportGO:00068111450.121
regulation of protein import into nucleusGO:0042306280.120
positive regulation of phosphate metabolic processGO:00459371390.119
axonogenesisGO:00074092900.116
locomotory behaviorGO:00076261760.111
cell cycle phase transitionGO:00447701400.105
regulation of intracellular signal transductionGO:19025312360.103
chromosome segregationGO:00070591570.102
neuroblast proliferationGO:0007405740.102
regulation of cellular localizationGO:00603411360.101
embryo development ending in birth or egg hatchingGO:00097921520.100
negative regulation of growthGO:0045926840.099
cell motilityGO:00488702510.099
regulation of transcription factor import into nucleusGO:0042990220.098
small gtpase mediated signal transductionGO:0007264880.098
catabolic processGO:00090564090.097
Mouse
modification dependent macromolecule catabolic processGO:0043632790.095
pronuclear migrationGO:003504640.095
maintenance of protein locationGO:0045185280.094
purine ribonucleoside triphosphate metabolic processGO:00092051190.094
modification dependent protein catabolic processGO:0019941780.093
positive regulation of protein metabolic processGO:00512471280.090
rhythmic processGO:00485111060.089
positive regulation of rna metabolic processGO:00512542710.089
actin filament based processGO:00300292200.088
nuclear transportGO:0051169720.087
aromatic compound catabolic processGO:00194391660.087
positive regulation of nucleobase containing compound metabolic processGO:00459353320.085
protein targeting to nucleusGO:0044744510.084
adult behaviorGO:00305341370.084
nephron epithelium morphogenesisGO:007208830.082
nephron morphogenesisGO:007202830.082
regulation of g1 s transition of mitotic cell cycleGO:2000045230.081
positive regulation of protein import into nucleusGO:0042307210.080
protein modification by small protein conjugation or removalGO:00706471060.079
fusome organizationGO:0045478130.078
single organism intracellular transportGO:19025822070.078
regulation of localizationGO:00328792750.078
protein targetingGO:0006605640.077
appendage morphogenesisGO:00351073970.076
positive regulation of proteolysisGO:0045862520.076
regulation of response to stressGO:00801342000.075
ubiquitin dependent protein catabolic processGO:0006511780.072
regulation of mapk cascadeGO:0043408920.072
positive regulation of protein transportGO:0051222370.071
positive regulation of transportGO:0051050920.070
lipid localizationGO:0010876540.070
cation transportGO:00068121100.070
transmembrane transportGO:00550851390.070
meiotic cell cycle processGO:19030461320.069
nucleoside triphosphate metabolic processGO:00091411200.069
regulation of behaviorGO:0050795750.069
regulation of microtubule based processGO:0032886490.067
dna integrity checkpointGO:0031570810.067
single organism cellular localizationGO:19025801800.067
segmentationGO:00352822070.066
maintenance of locationGO:0051235730.066
negative regulation of protein metabolic processGO:0051248850.066
secretionGO:00469031090.066
response to light stimulusGO:00094161240.065
mitotic cell cycle checkpointGO:0007093880.065
nephron tubule morphogenesisGO:007207830.064
renal tubule developmentGO:0061326640.064
axon guidanceGO:00074112330.064
protein phosphorylationGO:00064681690.064
purine ribonucleoside metabolic processGO:00461281270.064
regulation of neuron projection developmentGO:0010975690.063
negative regulation of cell cycle processGO:00109481090.062
circadian rhythmGO:00076231050.062
positive regulation of nitrogen compound metabolic processGO:00511733540.062
regulation of ras protein signal transductionGO:0046578930.061
lipid storageGO:0019915380.061
positive regulation of cellular component biogenesisGO:0044089800.061
regulation of protein localization to nucleusGO:1900180290.061
regulation of immune responseGO:00507761180.060
ras protein signal transductionGO:0007265880.060
regulation of protein localizationGO:0032880760.058
negative regulation of mitotic cell cycleGO:00459301090.058
positive regulation of phosphorus metabolic processGO:00105621390.057
positive regulation of protein localization to nucleusGO:1900182210.057
organonitrogen compound metabolic processGO:19015643180.056
proteolysisGO:00065081920.056
nephron epithelium developmentGO:007200930.054
regulation of protein catabolic processGO:0042176550.054
cytoplasmic transportGO:00164821300.053
regulation of phosphorus metabolic processGO:00511742100.052
substrate dependent cell migration cell extensionGO:000693030.052
taxisGO:00423303040.052
germline ring canal formationGO:0030725130.052
dna metabolic processGO:00062592270.052
mitotic cell cycle phase transitionGO:00447721380.051
pseudocleavage involved in syncytial blastoderm formationGO:003058990.051
determination of adult lifespanGO:00083401370.051
nuclear importGO:0051170510.051
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.050
amine metabolic processGO:0009308120.049
meiotic chromosome segregationGO:0045132590.049
body morphogenesisGO:001017120.048
protein complex biogenesisGO:00702712010.047
regulation of cellular protein metabolic processGO:00322682430.047
organelle fissionGO:00482853400.047
renal tubule morphogenesisGO:0061333440.047
regulation of multicellular organism growthGO:0040014400.047
protein localization to organelleGO:0033365820.046
positive regulation of growthGO:0045927750.046
oocyte axis specificationGO:00073091080.046
positive regulation of cellular biosynthetic processGO:00313283160.046
regulation of protein targetingGO:1903533290.045
signal transduction by phosphorylationGO:00230141070.044
agingGO:00075681430.044
positive regulation of multicellular organism growthGO:0040018210.044
deathGO:00162652840.043
proteolysis involved in cellular protein catabolic processGO:0051603830.043
nephron tubule developmentGO:007208030.042
purine ribonucleotide metabolic processGO:00091501450.042
germ line cyst formationGO:0048134440.042
response to organic cyclic compoundGO:0014070890.042
g2 dna damage checkpointGO:0031572690.041
regulation of cell adhesionGO:0030155270.041
multi organism reproductive behaviorGO:00447051210.041
camera type eye developmentGO:004301040.041
stress activated mapk cascadeGO:0051403520.040
molting cycleGO:0042303560.040
forebrain developmentGO:003090020.040
regulation of cell cycle processGO:00105641810.040
positive regulation of catabolic processGO:00098961050.040
positive regulation of response to stimulusGO:00485843230.040
nucleobase containing compound catabolic processGO:00346551650.040
nephron developmentGO:007200630.038
head developmentGO:00603221350.038
positive regulation of phosphorylationGO:0042327870.038
neuron projection guidanceGO:00974852410.038
defense response to other organismGO:00985422250.038
single organism catabolic processGO:00447122280.037
regulation of cell shapeGO:00083601130.037
negative regulation of nervous system developmentGO:0051961920.037
positive regulation of intracellular protein transportGO:0090316300.036
lysosomal transportGO:0007041130.036
posttranscriptional regulation of gene expressionGO:00106081450.036
proteasomal protein catabolic processGO:0010498590.036
positive regulation of transcription factor import into nucleusGO:0042993190.035
spindle assemblyGO:0051225800.035
nucleocytoplasmic transportGO:0006913720.035
cellular catabolic processGO:00442483720.034
dna damage checkpointGO:0000077780.034
meiosis iGO:0007127590.034
nucleoside metabolic processGO:00091161270.034
establishment or maintenance of cytoskeleton polarityGO:0030952440.034
regulation of phosphorylationGO:00423251470.034
mitotic nuclear divisionGO:00070672130.033
female germ line cyst formationGO:0048135420.033
positive regulation of nucleocytoplasmic transportGO:0046824240.033
organic hydroxy compound metabolic processGO:1901615830.033
positive regulation of macromolecule metabolic processGO:00106044050.032
establishment of protein localization to organelleGO:0072594620.032
cell adhesionGO:00071551360.032
wound healingGO:0042060750.032
positive regulation of developmental growthGO:0048639620.031
regulation of catabolic processGO:00098941700.031
protein localizationGO:00081042840.031
negative regulation of cellular protein metabolic processGO:0032269850.031
multi organism behaviorGO:00517051750.031
protein complex assemblyGO:00064612000.030
protein modification processGO:00362114380.030
synaptic transmissionGO:00072682880.029
negative regulation of gene expressionGO:00106293870.029
morphogenesis of embryonic epitheliumGO:0016331940.029
negative regulation of cellular component organizationGO:00511291080.028
post embryonic appendage morphogenesisGO:00351203850.028
spindle elongationGO:0051231830.028
establishment of oocyte nucleus localization involved in oocyte dorsal ventral axis specificationGO:003072260.028
mitotic g2 m transition checkpointGO:0044818700.028
substrate dependent cell migrationGO:000692930.028
eye morphogenesisGO:00485922600.028
imaginal disc pattern formationGO:0007447910.027
regulation of neuron differentiationGO:00456641030.027
epithelial cell migrationGO:00106311480.027
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052240.027
purine nucleoside metabolic processGO:00422781270.027
multicellular organismal agingGO:00102591400.027
positive regulation of protein catabolic processGO:0045732340.026
regulation of cell cell adhesionGO:0022407210.026
ion transmembrane transportGO:00342201220.026
regulation of cellular amine metabolic processGO:003323830.026
regulation of molecular functionGO:00650092170.026
cellular protein localizationGO:00346131600.026
positive regulation of developmental processGO:00510941430.026
positive regulation of mitotic cell cycleGO:0045931340.025
positive regulation of signalingGO:00230562430.025
gland morphogenesisGO:00226121450.025
rrna processingGO:000636430.025
mapk cascadeGO:00001651070.025
peptidyl amino acid modificationGO:00181931050.024
actin cytoskeleton organizationGO:00300362060.024
gliogenesisGO:0042063800.023
positive regulation of nucleic acid templated transcriptionGO:19035082660.023
meiotic cytokinesisGO:0033206330.023
positive regulation of cell communicationGO:00106472500.022
positive regulation of cellular response to insulin stimulusGO:190007840.022
maintenance of location in cellGO:0051651280.022
regulation of erk1 and erk2 cascadeGO:0070372390.022
regulation of gene silencingGO:0060968630.022
regulation of stress activated protein kinase signaling cascadeGO:0070302420.022
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.022
regulation of microtubule cytoskeleton organizationGO:0070507410.022
ovarian follicle cell developmentGO:00307072480.022
plasma membrane organizationGO:0007009260.022
positive regulation of intracellular signal transductionGO:19025331160.022
spermatogenesisGO:00072832000.022
positive regulation of signal transductionGO:00099672230.021
response to endogenous stimulusGO:00097191190.021
mrna splice site selectionGO:000637610.021
regulation of meiotic cell cycleGO:005144590.021
cell fate determinationGO:0001709910.021
negative regulation of neurogenesisGO:0050768530.021
positive regulation of macromolecule biosynthetic processGO:00105572830.021
cellular macromolecule catabolic processGO:00442651360.021
compound eye photoreceptor cell differentiationGO:00017511400.021
regulation of synaptic transmissionGO:0050804690.021
nucleotide catabolic processGO:00091661090.021
single organism biosynthetic processGO:00447112060.021
positive regulation of biosynthetic processGO:00098913160.021
dna replicationGO:0006260480.020
morphogenesis of an epitheliumGO:00020092760.020
microtubule organizing center organizationGO:00310231680.020
positive regulation of cellular catabolic processGO:0031331950.020
nucleoside phosphate catabolic processGO:19012921100.020
negative regulation of developmental growthGO:0048640640.020
positive regulation of gtp catabolic processGO:0033126430.020
salivary gland developmentGO:00074311620.020
single organismal cell cell adhesionGO:0016337450.020
eye developmentGO:00016543230.020
mitotic dna damage checkpointGO:0044773740.019
positive regulation of dendrite developmentGO:190000690.019
regulation of nuclear divisionGO:0051783580.019
ovipositionGO:0018991190.019
response to organonitrogen compoundGO:0010243750.019
stress activated protein kinase signaling cascadeGO:0031098550.019
regulation of multi organism processGO:00439001310.019
negative regulation of protein export from nucleusGO:004682620.018
regulation of dendrite morphogenesisGO:0048814280.018
developmental maturationGO:00217001720.018
positive regulation of rna biosynthetic processGO:19026802660.018
polarity specification of anterior posterior axisGO:000994950.018
unidimensional cell growthGO:0009826150.018
endomembrane system organizationGO:00102561190.018
protein catabolic processGO:00301631010.018
Mouse
cellular amine metabolic processGO:0044106120.018
male gamete generationGO:00482322010.018
regulation of small gtpase mediated signal transductionGO:0051056930.018
positive regulation of cellular protein catabolic processGO:1903364240.018
nucleobase containing small molecule metabolic processGO:00550861740.018
spermatid differentiationGO:00485151140.017
localization of cellGO:00516742570.017
jnk cascadeGO:0007254500.017
oocyte differentiationGO:00099941450.017
small molecule metabolic processGO:00442813050.017
heterocycle catabolic processGO:00467001660.017
positive regulation of intracellular transportGO:0032388420.017
organelle assemblyGO:00709251980.017
olfactory learningGO:0008355560.016
germarium derived oocyte fate determinationGO:0007294260.016
neurological system processGO:00508773580.016
organophosphate metabolic processGO:00196371950.016
negative regulation of homeostatic processGO:003284520.016
ribonucleoside triphosphate metabolic processGO:00091991190.016
kidney morphogenesisGO:006099330.016
positive regulation of cell cycleGO:0045787430.015
dendritic spine developmentGO:006099640.015
secretion by cellGO:00329401010.015
adult locomotory behaviorGO:0008344760.015
biological adhesionGO:00226101380.015
protein polymerizationGO:0051258420.015
regulation of neurogenesisGO:00507671580.015
response to woundingGO:0009611940.015
spindle organizationGO:00070512530.015
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.015
stem cell maintenanceGO:0019827670.015
central nervous system neuron differentiationGO:002195380.015
regulation of hemocyte proliferationGO:0035206370.014
ribonucleoside catabolic processGO:00424541120.014
apoptotic processGO:00069151590.014
stem cell developmentGO:0048864790.014
negative regulation of cellular metabolic processGO:00313243820.014
pigmentationGO:0043473750.014
negative regulation of cell cell adhesionGO:002240880.014
positive regulation of hydrolase activityGO:0051345780.014
negative regulation of sequestering of calcium ionGO:005128320.014
endosomal transportGO:0016197440.014
muscle cell developmentGO:0055001500.014
regulation of cellular amino acid metabolic processGO:000652100.014
organic substance catabolic processGO:19015753080.014
Mouse
regulation of cytoskeleton organizationGO:0051493890.014
response to organic substanceGO:00100332840.014
purine nucleoside triphosphate metabolic processGO:00091441190.014
positive regulation of defense responseGO:0031349590.014
axon extensionGO:0048675320.014
gene silencingGO:00164581380.013
regulation of cell motilityGO:2000145230.013
mitotic spindle organizationGO:00070522200.013
regulation of ras gtpase activityGO:0032318380.013
positive regulation of lipid metabolic processGO:004583440.013
ribonucleoside triphosphate catabolic processGO:00092031080.013
regulation of translationGO:0006417560.013
purine nucleotide catabolic processGO:00061951090.013
organophosphate catabolic processGO:00464341120.013
regulation of anatomical structure morphogenesisGO:00226032420.013
response to bacteriumGO:00096171980.013
associative learningGO:0008306650.013
axis specificationGO:00097981670.013
programmed cell deathGO:00125012570.013
lipid metabolic processGO:00066291210.013
cytosolic calcium ion transportGO:006040120.013
positive regulation of cell motilityGO:200014730.013
regulation of purine nucleotide metabolic processGO:1900542620.013
macromolecule catabolic processGO:00090571610.013
Mouse
negative regulation of nucleotide metabolic processGO:004598040.013
response to oxygen containing compoundGO:19017002000.012
cellular protein modification processGO:00064644380.012
germ line stem cell maintenanceGO:0030718500.012
cellular lipid metabolic processGO:0044255830.012
regulation of cellular protein catabolic processGO:1903362440.012
response to lipopolysaccharideGO:003249640.012
purine nucleotide metabolic processGO:00061631460.012
multi multicellular organism processGO:00447061230.012
regulation of locomotionGO:0040012420.012
negative regulation of intrinsic apoptotic signaling pathwayGO:200124310.012
epithelial cell morphogenesisGO:0003382250.012
ncrna metabolic processGO:0034660430.012
single organism membrane organizationGO:0044802930.012
cell deathGO:00082192790.012
embryonic hindgut morphogenesisGO:0048619480.012
germarium derived female germ line cyst encapsulationGO:003070880.012
positive regulation of transcription dna templatedGO:00458932660.012
cell proliferationGO:00082832990.012
chemical homeostasisGO:0048878920.012
axon choice point recognitionGO:0016198260.011
cellular protein complex assemblyGO:0043623710.011
imaginal disc derived wing morphogenesisGO:00074763370.011
cystoblast divisionGO:0007282100.011
imaginal disc derived appendage developmentGO:00487373990.011
regulation of protein complex assemblyGO:0043254420.011
macromolecular complex assemblyGO:00650032560.011
positive regulation of synaptic growth at neuromuscular junctionGO:0045887260.011
nucleoside catabolic processGO:00091641120.011
nucleoside phosphate metabolic processGO:00067531620.011
phospholipid metabolic processGO:0006644230.011
circadian behaviorGO:0048512760.011
positive regulation of mapk cascadeGO:0043410630.011
negative regulation of synaptic growth at neuromuscular junctionGO:0045886390.011
anterior posterior axis specificationGO:00099481090.011
development of primary sexual characteristicsGO:0045137500.011
learningGO:0007612750.011
central nervous system developmentGO:00074172010.011
maternal determination of anterior posterior axis embryoGO:0008358740.011
positive regulation of immune system processGO:0002684680.011
peripheral nervous system developmentGO:0007422520.011
protein modification by small protein removalGO:0070646280.011
tissue morphogenesisGO:00487292970.010
oocyte constructionGO:00073081120.010
mrna metabolic processGO:00160711240.010
reproductive behaviorGO:00190981220.010
intercellular bridge organizationGO:0043063140.010
protein localization to membraneGO:0072657190.010
positive regulation of cellular protein metabolic processGO:00322701180.010
cellular response to organic substanceGO:00713101320.010
regulation of actin filament polymerizationGO:0030833250.010
g protein coupled receptor signaling pathwayGO:00071861360.010

Cul-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.012
nervous system diseaseDOID:86300.012