Drosophila melanogaster

164 known processes

Pax (Dmel_CG31794)

Paxillin

(Aliases: Dpax,PDLP,CG31794,CG18576,pax,DPaxillin,DPxn,Dmel\CG31794,CG18061,DPxn37,CT40481,CT42454)

Pax biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
myoblast fusionGO:0007520430.999
syncytium formation by plasma membrane fusionGO:0000768430.994
myotube differentiationGO:0014902460.977
syncytium formationGO:0006949430.908
muscle cell differentiationGO:00426921030.869
muscle structure developmentGO:00610612240.706
actin filament based processGO:00300292200.640
actin cytoskeleton organizationGO:00300362060.545
actin filament organizationGO:00070151260.432
imaginal disc derived appendage developmentGO:00487373990.291
negative regulation of signalingGO:00230572190.280
Human Mouse
regulation of myoblast fusionGO:190173960.270
regulation of muscle cell differentiationGO:005114780.264
immune system processGO:00023763470.235
Human Mouse
morphogenesis of an epitheliumGO:00020092760.218
Mouse
cell cell signaling involved in cell fate commitmentGO:00451682100.209
regulation of cell morphogenesisGO:00226041630.207
Human Mouse
post embryonic appendage morphogenesisGO:00351203850.206
tissue morphogenesisGO:00487292970.203
Mouse
embryo development ending in birth or egg hatchingGO:00097921520.201
cell adhesionGO:00071551360.186
Human Mouse
kidney developmentGO:000182230.186
kidney epithelium developmentGO:007207330.181
imaginal disc derived appendage morphogenesisGO:00351143950.176
wing disc morphogenesisGO:00074723440.152
positive regulation of signalingGO:00230562430.151
Human Mouse
imaginal disc derived wing morphogenesisGO:00074763370.144
regulation of hydrolase activityGO:0051336970.141
regulation of response to stressGO:00801342000.136
response to organic substanceGO:00100332840.121
Human Mouse
regulation of immune system processGO:00026821760.114
Human Mouse
regulation of cysteine type endopeptidase activityGO:2000116270.106
regulation of myotube differentiationGO:001083060.105
appendage morphogenesisGO:00351073970.100
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.099
Human
organelle assemblyGO:00709251980.094
muscle cell developmentGO:0055001500.094
appendage developmentGO:00487364010.092
intracellular signal transductionGO:00355563000.090
Mouse
striated muscle cell differentiationGO:0051146900.088
positive regulation of cell motilityGO:200014730.086
organic substance transportGO:00717022570.084
response to extracellular stimulusGO:00099911160.083
biological adhesionGO:00226101380.083
Human Mouse
lateral inhibitionGO:00463312060.082
positive regulation of signal transductionGO:00099672230.081
Human Mouse
striated muscle myosin thick filament assemblyGO:007168830.079
cell deathGO:00082192790.079
muscle attachmentGO:0016203360.078
positive regulation of response to stimulusGO:00485843230.077
Human Mouse
organonitrogen compound metabolic processGO:19015643180.074
cellular component assembly involved in morphogenesisGO:00109271510.074
protein localizationGO:00081042840.072
cellular catabolic processGO:00442483720.069
secretionGO:00469031090.067
cellular macromolecular complex assemblyGO:00346221530.066
negative regulation of gene expressionGO:00106293870.065
positive regulation of cell migrationGO:003033520.064
negative regulation of signal transductionGO:00099682060.064
Human Mouse
vesicle mediated transportGO:00161923810.063
protein modification processGO:00362114380.062
Mouse
actomyosin structure organizationGO:0031032560.061
purine ribonucleotide metabolic processGO:00091501450.061
single organism catabolic processGO:00447122280.059
regulation of localizationGO:00328792750.058
response to nutrient levelsGO:00316671140.058
cuticle developmentGO:0042335860.058
response to transforming growth factor betaGO:0071559180.057
Human Mouse
feeding behaviorGO:0007631500.056
positive regulation of cell communicationGO:00106472500.056
Human Mouse
cellular protein complex assemblyGO:0043623710.055
regulation of peptidase activityGO:0052547390.055
spermatid differentiationGO:00485151140.053
endocytosisGO:00068973100.053
lipid localizationGO:0010876540.052
defense responseGO:00069523000.051
muscle organ developmentGO:00075171270.051
single organism carbohydrate metabolic processGO:0044723720.048
regulation of wnt signaling pathwayGO:0030111680.048
catabolic processGO:00090564090.047
regulation of anatomical structure morphogenesisGO:00226032420.047
digestive system developmentGO:00551231490.047
response to starvationGO:0042594970.047
ribose phosphate metabolic processGO:00196931450.047
phosphorylationGO:00163102940.046
Mouse
cellular response to external stimulusGO:0071496660.046
exocrine system developmentGO:00352721620.045
positive regulation of intracellular signal transductionGO:19025331160.045
Mouse
body morphogenesisGO:001017120.044
guanosine containing compound catabolic processGO:1901069740.042
mitochondrion organizationGO:0007005650.041
wound healingGO:0042060750.041
organic acid metabolic processGO:00060821030.040
wnt signaling pathwayGO:0016055980.040
regulation of phosphorus metabolic processGO:00511742100.040
regulation of mapk cascadeGO:0043408920.040
Mouse
homeostatic processGO:00425921990.039
regulation of phosphate metabolic processGO:00192202100.039
regulation of intracellular signal transductionGO:19025312360.038
regulation of cellular localizationGO:00603411360.038
establishment of protein localizationGO:00451841630.038
myofibril assemblyGO:0030239360.037
carboxylic acid metabolic processGO:0019752920.037
regulation of notch signaling pathwayGO:00085931000.037
regulation of programmed cell deathGO:00430671520.036
nucleobase containing small molecule metabolic processGO:00550861740.036
positive regulation of wnt signaling pathwayGO:0030177250.035
mesoderm developmentGO:0007498780.034
negative regulation of response to stimulusGO:00485852580.034
Human Mouse
oxoacid metabolic processGO:00434361030.034
positive regulation of i kappab kinase nf kappab signalingGO:004312310.034
protein catabolic processGO:00301631010.034
Human
regulation of cellular component sizeGO:0032535980.034
renal system developmentGO:0072001720.033
regulation of catalytic activityGO:00507901850.033
regulation of mitotic cell cycleGO:00073461900.032
regulation of cell cycleGO:00517262910.032
nucleotide metabolic processGO:00091171610.032
positive regulation of cysteine type endopeptidase activityGO:2001056240.031
open tracheal system developmentGO:00074242040.031
regulation of striated muscle cell differentiationGO:005115380.031
embryonic morphogenesisGO:00485982060.030
Mouse
response to biotic stimulusGO:00096072940.030
cytoskeleton dependent cytokinesisGO:0061640810.029
protein phosphorylationGO:00064681690.029
Mouse
positive regulation of protein localization to nucleusGO:1900182210.029
myotube cell developmentGO:001490430.029
maintenance of locationGO:0051235730.029
response to organophosphorusGO:004668320.029
negative regulation of rna biosynthetic processGO:19026792400.029
negative regulation of nucleobase containing compound metabolic processGO:00459342610.028
cilium assemblyGO:0042384380.028
cellular response to starvationGO:0009267610.028
positive regulation of cell deathGO:0010942690.028
nephron epithelium developmentGO:007200930.028
cell proliferationGO:00082832990.028
salivary gland developmentGO:00074311620.028
actin cytoskeleton reorganizationGO:0031532220.028
regulation of syncytium formation by plasma membrane fusionGO:006014260.028
heart developmentGO:0007507820.027
carbohydrate metabolic processGO:0005975820.027
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.027
Human
negative regulation of multicellular organismal processGO:00512411420.027
protein secretionGO:0009306450.027
notch signaling pathwayGO:00072191200.026
immune responseGO:00069552460.026
regionalizationGO:00030024160.026
regulation of organ morphogenesisGO:2000027780.026
gland morphogenesisGO:00226121450.026
skeletal muscle organ developmentGO:0060538480.026
nephron tubule developmentGO:007208030.026
regulation of phosphorylationGO:00423251470.026
Mouse
mesenchymal cell differentiationGO:004876210.025
Human
response to external biotic stimulusGO:00432072930.025
regulation of i kappab kinase nf kappab signalingGO:004312220.025
establishment or maintenance of cell polarityGO:00071631670.025
skeletal muscle fiber developmentGO:004874130.024
positive regulation of programmed cell deathGO:0043068620.024
digestive tract morphogenesisGO:00485461270.024
gland developmentGO:00487321910.024
activation of cysteine type endopeptidase activityGO:0097202170.024
integrin mediated signaling pathwayGO:000722930.023
Mouse
positive regulation of protein complex assemblyGO:0031334220.023
urogenital system developmentGO:0001655720.023
deathGO:00162652840.023
cellular response to chemical stimulusGO:00708871990.022
Human Mouse
response to glucoseGO:000974920.022
cellular macromolecule localizationGO:00707272200.022
cellular response to extracellular stimulusGO:0031668640.021
actin filament bundle organizationGO:0061572280.021
respiratory system developmentGO:00605412130.021
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280230.021
positive regulation of cell proliferationGO:0008284470.021
sensory organ morphogenesisGO:00905962600.021
cell agingGO:000756920.021
compound eye morphogenesisGO:00017452490.021
cellular amino acid metabolic processGO:0006520610.021
regulation of cell deathGO:00109411730.021
striated muscle cell developmentGO:0055002500.020
regulation of organelle organizationGO:00330431960.020
response to abiotic stimulusGO:00096283410.020
Rat
regulation of cellular ketone metabolic processGO:001056530.020
regulation of stress activated mapk cascadeGO:0032872410.020
regulation of transportGO:00510491810.020
response to woundingGO:0009611940.020
response to lipidGO:0033993380.020
secretion by cellGO:00329401010.020
protein polymerizationGO:0051258420.020
lipid storageGO:0019915380.019
circulatory system developmentGO:0072359820.019
purine containing compound metabolic processGO:00725211550.019
heterocycle catabolic processGO:00467001660.019
protein complex assemblyGO:00064612000.019
regulation of cell differentiationGO:00455953020.019
establishment or maintenance of cytoskeleton polarityGO:0030952440.019
substrate adhesion dependent cell spreadingGO:003444620.018
Mouse
negative regulation of cell cycleGO:00457861160.018
autophagic vacuole assemblyGO:000004520.018
negative regulation of molecular functionGO:0044092510.018
cell divisionGO:00513012480.018
growthGO:00400073590.018
programmed cell deathGO:00125012570.018
compound eye developmentGO:00487493070.018
regulation of cell motilityGO:2000145230.018
regulation of actin cytoskeleton organizationGO:0032956420.018
immune response activating signal transductionGO:000275720.017
Human Mouse
forebrain developmentGO:003090020.017
nephron developmentGO:007200630.017
negative regulation of notch signaling pathwayGO:0045746410.017
regulation of cellular component biogenesisGO:00440872010.017
positive regulation of mapk cascadeGO:0043410630.017
Mouse
guanosine containing compound metabolic processGO:1901068740.016
connective tissue developmentGO:006144830.016
positive regulation of apoptotic processGO:0043065470.016
regulation of secretionGO:0051046440.016
eye morphogenesisGO:00485922600.016
nephron morphogenesisGO:007202830.016
response to nitrogen compoundGO:1901698900.016
Human
salivary gland morphogenesisGO:00074351450.016
cardiovascular system developmentGO:0072358820.016
cell cycle phase transitionGO:00447701400.016
multi organism behaviorGO:00517051750.016
neurotransmitter transportGO:0006836370.016
response to decreased oxygen levelsGO:0036293580.015
organonitrogen compound catabolic processGO:19015651280.015
cellular protein localizationGO:00346131600.015
response to hexoseGO:000974630.015
spermatogenesisGO:00072832000.015
positive regulation of molecular functionGO:00440931360.015
Mouse
carbohydrate derivative metabolic processGO:19011352170.015
mapk cascadeGO:00001651070.015
Mouse
positive regulation of protein transportGO:0051222370.015
proteolysisGO:00065081920.015
Human
positive regulation of cellular amine metabolic processGO:003324000.015
regulation of cellular amine metabolic processGO:003323830.015
cellular response to organic substanceGO:00713101320.014
Human Mouse
positive regulation of catalytic activityGO:00430851180.014
Mouse
positive regulation of cell developmentGO:0010720610.014
Human
response to organic cyclic compoundGO:0014070890.014
positive regulation of lipid metabolic processGO:004583440.014
response to other organismGO:00517072930.014
organic substance catabolic processGO:19015753080.014
response to endogenous stimulusGO:00097191190.014
Human Mouse
response to inorganic substanceGO:0010035440.014
positive regulation of hydrolase activityGO:0051345780.014
response to mercury ionGO:004668930.014
single organism biosynthetic processGO:00447112060.014
negative regulation of cell communicationGO:00106482230.014
Human Mouse
tube developmentGO:00352952440.013
Mouse
regulation of cell shapeGO:00083601130.013
Mouse
regulation of endopeptidase activityGO:0052548360.013
regulation of molecular functionGO:00650092170.013
cellular nitrogen compound catabolic processGO:00442701650.013
regulation of cellular amino acid metabolic processGO:000652100.013
epidermis developmentGO:0008544650.013
regulation of cellular component movementGO:0051270420.013
cellular protein modification processGO:00064644380.013
Mouse
single organismal cell cell adhesionGO:0016337450.013
positive regulation of phosphorylationGO:0042327870.013
Mouse
plasma membrane organizationGO:0007009260.013
mesenchymal cell developmentGO:001403110.012
Human
protein transportGO:00150311550.012
ion transportGO:00068111450.012
central nervous system developmentGO:00074172010.012
response to oxygen levelsGO:0070482590.012
single organism membrane organizationGO:0044802930.012
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.012
negative regulation of catalytic activityGO:0043086420.012
bmp signaling pathwayGO:0030509270.012
adherens junction assemblyGO:0034333110.012
Mouse
regulation of cell morphogenesis involved in differentiationGO:0010769610.012
Human
cell junction organizationGO:0034330570.012
Mouse
immune system developmentGO:0002520570.012
cellular response to oxygen containing compoundGO:1901701790.012
Human
establishment of localization in cellGO:00516494020.012
glycosyl compound metabolic processGO:19016571270.012
determination of adult lifespanGO:00083401370.012
organelle fissionGO:00482853400.012
regulation of cellular protein metabolic processGO:00322682430.012
Mouse
carbohydrate derivative biosynthetic processGO:1901137850.012
myosin filament assemblyGO:003103450.012
autophagyGO:00069141080.012
purine nucleoside triphosphate metabolic processGO:00091441190.012
nucleocytoplasmic transportGO:0006913720.012
leg disc morphogenesisGO:0007478800.011
extracellular matrix assemblyGO:0085029130.011
protein complex biogenesisGO:00702712010.011
phagocytosisGO:00069092150.011
single organism nuclear importGO:1902593510.011
cellular response to nutrient levelsGO:0031669620.011
anatomical structure homeostasisGO:0060249970.011
regulation of proteolysisGO:0030162870.011
multicellular organismal reproductive behaviorGO:00330571100.011
monovalent inorganic cation transportGO:0015672400.011
ribonucleoside biosynthetic processGO:004245530.011
positive regulation of protein import into nucleusGO:0042307210.011
protein targeting to nucleusGO:0044744510.011
regulation of mitotic cell cycle phase transitionGO:19019901300.011
cardiac muscle tissue developmentGO:004873890.011
chromatin silencingGO:0006342760.011
hematopoietic progenitor cell differentiationGO:000224410.011
apoptotic processGO:00069151590.010
regulation of establishment of protein localizationGO:0070201610.010
response to calcium ionGO:005159210.010
regulation of embryonic developmentGO:0045995680.010
negative regulation of cellular protein metabolic processGO:0032269850.010
regulation of anatomical structure sizeGO:00900661630.010
cellular ketone metabolic processGO:0042180240.010
imaginal disc derived wing margin morphogenesisGO:0008587410.010
positive regulation of cellular amino acid metabolic processGO:004576400.010
membrane organizationGO:00610241120.010
positive regulation of cellular protein metabolic processGO:00322701180.010
Mouse
adult behaviorGO:00305341370.010
cytoplasmic transportGO:00164821300.010
convergent extensionGO:006002620.010

Pax disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.035
disease of anatomical entityDOID:700.035
muscular diseaseDOID:008000000.017
cardiomyopathyDOID:005070000.017
heart diseaseDOID:11400.017
cardiovascular system diseaseDOID:128700.017
intrinsic cardiomyopathyDOID:006003600.017
muscle tissue diseaseDOID:6600.017
myopathyDOID:42300.017