IMP: Integrative Multi-species Prediction

Drosophila melanogaster

58 known processes

Cpn (Dmel_CG4795)

Calphotin

(Aliases: Dmel\CG4795,cap,cpn,Ag 72H5,77H5,Ag72H5,CG4795,Mab77H5)

Entrez: 41474
FLYBASE: FBgn0261714
UniProtKB: Q02910

Process Predictions
Disease Predictions

Cpn biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
sensory perception of mechanical stimulus	GO:0050954	72	0.440
regulation of multicellular organismal development	GO:2000026	414	0.364
intracellular transport	GO:0046907	228	0.343
body morphogenesis	GO:0010171	2	0.214
morphogenesis of an epithelium	GO:0002009	276	0.181
establishment of localization in cell	GO:0051649	402	0.172
protein localization	GO:0008104	284	0.169
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.161
tube development	GO:0035295	244	0.154
tube morphogenesis	GO:0035239	191	0.154
kidney development	GO:0001822	3	0.152
single organism catabolic process	GO:0044712	228	0.147
regulation of localization	GO:0032879	275	0.146
cellular catabolic process	GO:0044248	372	0.144
regulation of cellular localization	GO:0060341	136	0.139
sensory perception	GO:0007600	196	0.120
neurological system process	GO:0050877	358	0.112
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.111
cell projection assembly	GO:0030031	94	0.102
foregut morphogenesis	GO:0007440	10	0.102
regulation of transport	GO:0051049	181	0.100
catabolic process	GO:0009056	409	0.098
protein transport	GO:0015031	155	0.093
compound eye development	GO:0048749	307	0.087
positive regulation of protein transport	GO:0051222	37	0.084
carbohydrate derivative metabolic process	GO:1901135	217	0.083
regulation of cellular component biogenesis	GO:0044087	201	0.080
growth	GO:0040007	359	0.075
appendage morphogenesis	GO:0035107	397	0.075
regulation of cell development	GO:0060284	215	0.074
single organism cell adhesion	GO:0098602	47	0.072
tissue morphogenesis	GO:0048729	297	0.070
regulation of cytoplasmic transport	GO:1903649	47	0.070
cuticle development	GO:0042335	86	0.070
positive regulation of developmental process	GO:0051094	143	0.068
regulation of anatomical structure morphogenesis	GO:0022603	242	0.067
columnar cuboidal epithelial cell development	GO:0002066	249	0.066
vesicle mediated transport	GO:0016192	381	0.065
cellular response to starvation	GO:0009267	61	0.065
sensory perception of sound	GO:0007605	56	0.064
photoreceptor cell differentiation	GO:0046530	170	0.064
regulation of catabolic process	GO:0009894	170	0.064
negative regulation of rna biosynthetic process	GO:1902679	240	0.063
epithelial cell differentiation	GO:0030855	322	0.063
eye morphogenesis	GO:0048592	260	0.061
positive regulation of intracellular protein transport	GO:0090316	30	0.060
imaginal disc derived appendage development	GO:0048737	399	0.060
eye development	GO:0001654	323	0.057
negative regulation of cellular biosynthetic process	GO:0031327	277	0.056
endocytosis	GO:0006897	310	0.055
regulation of protein transport	GO:0051223	57	0.055
regulation of protein localization	GO:0032880	76	0.054
organic substance transport	GO:0071702	257	0.054
regulation of intracellular transport	GO:0032386	64	0.053
negative regulation of transcription dna templated	GO:0045892	237	0.053
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.053
establishment of tissue polarity	GO:0007164	87	0.052
epithelial cell development	GO:0002064	274	0.051
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.051
cellular macromolecule localization	GO:0070727	220	0.051
regulation of programmed cell death	GO:0043067	152	0.050
negative regulation of gene expression	GO:0010629	387	0.050
single organismal cell cell adhesion	GO:0016337	45	0.050
establishment of planar polarity	GO:0001736	87	0.050
transcription from rna polymerase ii promoter	GO:0006366	368	0.049
negative regulation of developmental process	GO:0051093	201	0.047
regulation of developmental growth	GO:0048638	174	0.047
regulation of organelle organization	GO:0033043	196	0.047
digestive tract morphogenesis	GO:0048546	127	0.047
proteolysis	GO:0006508	192	0.046
organic acid metabolic process	GO:0006082	103	0.046
macromolecular complex assembly	GO:0065003	256	0.046
cellular nitrogen compound catabolic process	GO:0044270	165	0.045
positive regulation of transport	GO:0051050	92	0.045
sensory organ morphogenesis	GO:0090596	260	0.044
cellular response to nutrient levels	GO:0031669	62	0.044
establishment of protein localization	GO:0045184	163	0.044
cytoplasmic transport	GO:0016482	130	0.043
positive regulation of intracellular transport	GO:0032388	42	0.043
single organism membrane organization	GO:0044802	93	0.043
appendage development	GO:0048736	401	0.043
ribonucleoside metabolic process	GO:0009119	127	0.042
glycosyl compound catabolic process	GO:1901658	112	0.042
renal system development	GO:0072001	72	0.042
organic substance catabolic process	GO:1901575	308	0.042
negative regulation of multicellular organismal process	GO:0051241	142	0.042
regulation of establishment of protein localization	GO:0070201	61	0.041
purine ribonucleotide catabolic process	GO:0009154	109	0.041
cellular response to extracellular stimulus	GO:0031668	64	0.041
compound eye morphogenesis	GO:0001745	249	0.041
protein maturation	GO:0051604	71	0.040
aging	GO:0007568	143	0.040
purine nucleoside metabolic process	GO:0042278	127	0.040
single organism intracellular transport	GO:1902582	207	0.040
membrane organization	GO:0061024	112	0.039
protein complex biogenesis	GO:0070271	201	0.038
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.038
negative regulation of biosynthetic process	GO:0009890	277	0.038
purine nucleotide catabolic process	GO:0006195	109	0.037
rhabdomere development	GO:0042052	38	0.037
response to nutrient levels	GO:0031667	114	0.037
actin filament based process	GO:0030029	220	0.037
neuromuscular junction development	GO:0007528	149	0.037
regulation of intracellular signal transduction	GO:1902531	236	0.036
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.036
biological adhesion	GO:0022610	138	0.036
eye photoreceptor cell differentiation	GO:0001754	145	0.035
nucleoside phosphate catabolic process	GO:1901292	110	0.035
regionalization	GO:0003002	416	0.035
positive regulation of signal transduction	GO:0009967	223	0.035
negative regulation of rna metabolic process	GO:0051253	251	0.035
death	GO:0016265	284	0.034
regulation of cellular catabolic process	GO:0031329	157	0.034
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.034
regulation of cell cycle phase transition	GO:1901987	130	0.034
cellular amide metabolic process	GO:0043603	80	0.033
programmed cell death	GO:0012501	257	0.033
nucleoside triphosphate catabolic process	GO:0009143	108	0.033
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.033
establishment or maintenance of cell polarity	GO:0007163	167	0.033
ribonucleoside catabolic process	GO:0042454	112	0.032
intracellular protein transport	GO:0006886	104	0.032
stem cell development	GO:0048864	79	0.032
nucleotide catabolic process	GO:0009166	109	0.031
protein processing	GO:0016485	68	0.031
regulation of vesicle mediated transport	GO:0060627	59	0.031
regulation of nervous system development	GO:0051960	248	0.031
regulation of cell death	GO:0010941	173	0.031
response to organic substance	GO:0010033	284	0.031
forebrain development	GO:0030900	2	0.031
exocrine system development	GO:0035272	162	0.031
chitin based cuticle development	GO:0040003	49	0.030
negative regulation of cell differentiation	GO:0045596	143	0.030
cell death	GO:0008219	279	0.030
regulation of growth	GO:0040008	233	0.029
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.029
cell proliferation	GO:0008283	299	0.029
digestive tract development	GO:0048565	149	0.029
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.028
telencephalon development	GO:0021537	2	0.028
cell adhesion	GO:0007155	136	0.027
androgen metabolic process	GO:0008209	1	0.027
gtp catabolic process	GO:0006184	72	0.027
regulation of microtubule based process	GO:0032886	49	0.027
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.027
eye photoreceptor cell development	GO:0042462	81	0.026
negative regulation of cell cycle phase transition	GO:1901988	103	0.026
positive regulation of cellular catabolic process	GO:0031331	95	0.025
organonitrogen compound catabolic process	GO:1901565	128	0.025
purine ribonucleoside metabolic process	GO:0046128	127	0.025
purine ribonucleotide metabolic process	GO:0009150	145	0.024
negative regulation of synapse assembly	GO:0051964	39	0.024
heterocycle catabolic process	GO:0046700	166	0.024
skin development	GO:0043588	65	0.024
negative regulation of response to stimulus	GO:0048585	258	0.024
purine nucleotide metabolic process	GO:0006163	146	0.023
nucleotide metabolic process	GO:0009117	161	0.023
compound eye photoreceptor development	GO:0042051	78	0.023
negative regulation of signaling	GO:0023057	219	0.023
germarium derived egg chamber formation	GO:0007293	101	0.023
negative regulation of apoptotic process	GO:0043066	63	0.023
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.023
response to oxygen containing compound	GO:1901700	200	0.022
cell cycle phase transition	GO:0044770	140	0.022
regulation of cellular protein metabolic process	GO:0032268	243	0.022
glycosyl compound metabolic process	GO:1901657	127	0.022
homeostatic process	GO:0042592	199	0.022
positive regulation of hydrolase activity	GO:0051345	78	0.022
regulation of organ morphogenesis	GO:2000027	78	0.022
cellular response to chemical stimulus	GO:0070887	199	0.022
imaginal disc derived wing morphogenesis	GO:0007476	337	0.022
response to starvation	GO:0042594	97	0.022
carbohydrate derivative catabolic process	GO:1901136	118	0.022
mesenchymal cell development	GO:0014031	1	0.022
dna integrity checkpoint	GO:0031570	81	0.022
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.021
cellular response to oxygen containing compound	GO:1901701	79	0.021
wing disc morphogenesis	GO:0007472	344	0.021
nucleobase containing compound catabolic process	GO:0034655	165	0.021
intracellular signal transduction	GO:0035556	300	0.021
gland development	GO:0048732	191	0.021
regulation of synapse organization	GO:0050807	110	0.021
protein complex assembly	GO:0006461	200	0.021
organelle fusion	GO:0048284	46	0.021
salivary gland morphogenesis	GO:0007435	145	0.021
single organism cellular localization	GO:1902580	180	0.021
cellular protein localization	GO:0034613	160	0.020
maintenance of location	GO:0051235	73	0.020
regulation of cell differentiation	GO:0045595	302	0.020
positive regulation of nucleocytoplasmic transport	GO:0046824	24	0.020
response to extracellular stimulus	GO:0009991	116	0.020
developmental maturation	GO:0021700	172	0.020
response to glucose	GO:0009749	2	0.020
regulation of cellular ketone metabolic process	GO:0010565	3	0.020
ribonucleotide catabolic process	GO:0009261	109	0.020
defense response to bacterium	GO:0042742	178	0.020
mesenchymal cell differentiation	GO:0048762	1	0.020
negative regulation of signal transduction	GO:0009968	206	0.020
negative regulation of cellular component organization	GO:0051129	108	0.020
cell junction organization	GO:0034330	57	0.019
immune response regulating signaling pathway	GO:0002764	2	0.019
purine containing compound catabolic process	GO:0072523	112	0.019
actin cytoskeleton organization	GO:0030036	206	0.019
negative regulation of nervous system development	GO:0051961	92	0.019
nucleoside metabolic process	GO:0009116	127	0.019
regulation of molecular function	GO:0065009	217	0.019
macromolecule catabolic process	GO:0009057	161	0.019
carbohydrate derivative biosynthetic process	GO:1901137	85	0.019
dna damage checkpoint	GO:0000077	78	0.019
response to abiotic stimulus	GO:0009628	341	0.019
positive regulation of response to stimulus	GO:0048584	323	0.019
ribonucleotide metabolic process	GO:0009259	145	0.019
cellular protein complex assembly	GO:0043623	71	0.019
purine containing compound metabolic process	GO:0072521	155	0.019
cell cell junction organization	GO:0045216	55	0.018
regulation of cell morphogenesis	GO:0022604	163	0.018
epidermal cell differentiation	GO:0009913	51	0.018
negative regulation of cell death	GO:0060548	81	0.018
cell cycle checkpoint	GO:0000075	95	0.018
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.018
regulation of anatomical structure size	GO:0090066	163	0.018
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.018
positive regulation of catalytic activity	GO:0043085	118	0.018
purine ribonucleoside catabolic process	GO:0046130	112	0.018
regulation of cell cycle	GO:0051726	291	0.017
negative regulation of organelle organization	GO:0010639	56	0.017
single organism carbohydrate metabolic process	GO:0044723	72	0.017
positive regulation of signaling	GO:0023056	243	0.017
regulation of catalytic activity	GO:0050790	185	0.017
post embryonic appendage morphogenesis	GO:0035120	385	0.017
aromatic compound catabolic process	GO:0019439	166	0.017
protein targeting	GO:0006605	64	0.016
positive regulation of intracellular signal transduction	GO:1902533	116	0.016
negative regulation of mitotic cell cycle	GO:0045930	109	0.016
cell cell junction assembly	GO:0007043	38	0.016
cardiovascular system development	GO:0072358	82	0.016
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.016
immune response activating signal transduction	GO:0002757	2	0.016
regulation of cell adhesion	GO:0030155	27	0.016
ribose phosphate metabolic process	GO:0019693	145	0.016
cellular response to oxidative stress	GO:0034599	28	0.016
regulation of cysteine type endopeptidase activity	GO:2000116	27	0.016
regulation of hydrolase activity	GO:0051336	97	0.016
endomembrane system organization	GO:0010256	119	0.016
cellular macromolecular complex assembly	GO:0034622	153	0.016
response to monosaccharide	GO:0034284	4	0.016
regulation of synaptic growth at neuromuscular junction	GO:0008582	89	0.016
developmental growth	GO:0048589	280	0.016
circulatory system development	GO:0072359	82	0.015
guanosine containing compound metabolic process	GO:1901068	74	0.015
post golgi vesicle mediated transport	GO:0006892	11	0.015
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.015
regulation of protein complex assembly	GO:0043254	42	0.015
protein localization to plasma membrane	GO:0072659	13	0.015
phagocytosis	GO:0006909	215	0.015
single organism nuclear import	GO:1902593	51	0.015
response to radiation	GO:0009314	155	0.015
dendrite morphogenesis	GO:0048813	199	0.015
mitochondrion organization	GO:0007005	65	0.015
urogenital system development	GO:0001655	72	0.015
positive regulation of immune system process	GO:0002684	68	0.015
cellular amino acid metabolic process	GO:0006520	61	0.015
regulation of mitotic cell cycle	GO:0007346	190	0.015
adherens junction organization	GO:0034332	27	0.014
lipid localization	GO:0010876	54	0.014
carbohydrate metabolic process	GO:0005975	82	0.014
nucleoside phosphate metabolic process	GO:0006753	162	0.014
pigmentation	GO:0043473	75	0.014
negative regulation of cellular metabolic process	GO:0031324	382	0.014
protein import	GO:0017038	55	0.014
regulation of nucleocytoplasmic transport	GO:0046822	35	0.014
single organism behavior	GO:0044708	391	0.014
positive regulation of protein localization to nucleus	GO:1900182	21	0.014
positive regulation of exocytosis	GO:0045921	4	0.014
small gtpase mediated signal transduction	GO:0007264	88	0.014
single organism biosynthetic process	GO:0044711	206	0.014
regulation of cell cycle process	GO:0010564	181	0.014
actin filament organization	GO:0007015	126	0.014
positive regulation of apoptotic signaling pathway	GO:2001235	4	0.014
head development	GO:0060322	135	0.014
synaptic vesicle localization	GO:0097479	53	0.014
organic cyclic compound catabolic process	GO:1901361	168	0.013
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.013
stem cell differentiation	GO:0048863	117	0.013
purine nucleoside catabolic process	GO:0006152	112	0.013
response to inorganic substance	GO:0010035	44	0.013
cellular ketone metabolic process	GO:0042180	24	0.013
response to lipopolysaccharide	GO:0032496	4	0.013
sex differentiation	GO:0007548	81	0.013
chemotaxis	GO:0006935	249	0.013
negative regulation of protein metabolic process	GO:0051248	85	0.013
neuromuscular synaptic transmission	GO:0007274	67	0.013
protein modification by small protein conjugation	GO:0032446	79	0.013
nucleobase containing small molecule metabolic process	GO:0055086	174	0.013
regulation of mapk cascade	GO:0043408	92	0.013
organophosphate catabolic process	GO:0046434	112	0.013
phototransduction	GO:0007602	52	0.013
adult behavior	GO:0030534	137	0.013
histolysis	GO:0007559	102	0.013
mitotic g2 m transition checkpoint	GO:0044818	70	0.013
organonitrogen compound metabolic process	GO:1901564	318	0.013
cellular component assembly involved in morphogenesis	GO:0010927	151	0.013
axon development	GO:0061564	297	0.013
cell junction assembly	GO:0034329	42	0.013
carboxylic acid metabolic process	GO:0019752	92	0.012
anatomical structure homeostasis	GO:0060249	97	0.012
autophagic cell death	GO:0048102	83	0.012
epidermis development	GO:0008544	65	0.012
protein catabolic process	GO:0030163	101	0.012
ameboidal type cell migration	GO:0001667	151	0.012
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.012
axonogenesis	GO:0007409	290	0.012
nuclear transport	GO:0051169	72	0.012
microtubule based movement	GO:0007018	51	0.012
positive regulation of cell communication	GO:0010647	250	0.012
secretion	GO:0046903	109	0.012
protein modification process	GO:0036211	438	0.012
developmental programmed cell death	GO:0010623	138	0.012
cellular response to dna damage stimulus	GO:0006974	223	0.012
lateral inhibition	GO:0046331	206	0.012
regulation of cellular component size	GO:0032535	98	0.012
adult locomotory behavior	GO:0008344	76	0.012
hematopoietic progenitor cell differentiation	GO:0002244	1	0.012
taxis	GO:0042330	304	0.012
gtp metabolic process	GO:0046039	72	0.012
positive regulation of cellular protein metabolic process	GO:0032270	118	0.012
regulation of protein import into nucleus	GO:0042306	28	0.012
detection of light stimulus	GO:0009583	58	0.011
synaptic transmission	GO:0007268	288	0.011
ras protein signal transduction	GO:0007265	88	0.011
response to hexose	GO:0009746	3	0.011
positive regulation of molecular function	GO:0044093	136	0.011
negative regulation of cell cycle process	GO:0010948	109	0.011
establishment of protein localization to plasma membrane	GO:0090002	9	0.011
establishment of organelle localization	GO:0051656	122	0.011
calcium ion homeostasis	GO:0055074	23	0.011
regulation of notch signaling pathway	GO:0008593	100	0.011
gene silencing	GO:0016458	138	0.011
brain development	GO:0007420	120	0.011
salivary gland development	GO:0007431	162	0.011
regulation of circadian rhythm	GO:0042752	49	0.011
regulation of gene silencing	GO:0060968	63	0.011
sensory perception of touch	GO:0050975	11	0.011
regulation of mitosis	GO:0007088	56	0.011
positive regulation of mapk cascade	GO:0043410	63	0.011
posttranscriptional regulation of gene expression	GO:0010608	145	0.011
positive regulation of catabolic process	GO:0009896	105	0.011
rhythmic process	GO:0048511	106	0.011
regulation of cellular response to stress	GO:0080135	89	0.011
mitotic cell cycle phase transition	GO:0044772	138	0.011
nucleocytoplasmic transport	GO:0006913	72	0.011
divalent inorganic cation homeostasis	GO:0072507	29	0.011
regulation of cell size	GO:0008361	63	0.011
synaptic growth at neuromuscular junction	GO:0051124	119	0.010
positive regulation of proteolysis	GO:0045862	52	0.010
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.010
establishment of protein localization to organelle	GO:0072594	62	0.010
regulation of membrane potential	GO:0042391	35	0.010
negative regulation of cellular protein metabolic process	GO:0032269	85	0.010
cell maturation	GO:0048469	144	0.010
response to temperature stimulus	GO:0009266	106	0.010
negative regulation of developmental growth	GO:0048640	64	0.010
rho protein signal transduction	GO:0007266	14	0.010
compound eye photoreceptor cell differentiation	GO:0001751	140	0.010
rna processing	GO:0006396	147	0.010
negative regulation of cell communication	GO:0010648	223	0.010
tissue migration	GO:0090130	155	0.010
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.010

Cpn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.022

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