Drosophila melanogaster

119 known processes

eIF-4a (Dmel_CG9075)

Eukaryotic initiation factor 4a

(Aliases: 2439,9075,Dm-eIF4A,l(2)k01501,anon26A,eIF4a,l(2)gdh-4,l(2)162,eIF-4A,l(2)26Ac,Eif-4a,eIF4A,l(2L)162,eIF 4A,EiF4A,eIF-4a-I,EIF-4A,l(2)02439,Dmel\CG9075,DmRH2,anon-26Aa,Eif4a,eif-4a,CG9075,Su(dpp)YE9,eif4A)

eIF-4a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
nuclear divisionGO:00002803320.974
axon developmentGO:00615642970.944
positive regulation of gene expressionGO:00106282900.913
cell deathGO:00082192790.861
apoptotic processGO:00069151590.847
oocyte developmentGO:00485991240.845
exocrine system developmentGO:00352721620.843
deathGO:00162652840.824
translationGO:0006412690.753
Yeast
embryo development ending in birth or egg hatchingGO:00097921520.743
Worm
oocyte differentiationGO:00099941450.731
programmed cell deathGO:00125012570.697
salivary gland morphogenesisGO:00074351450.668
growthGO:00400073590.617
histolysisGO:00075591020.591
organelle fissionGO:00482853400.584
organelle assemblyGO:00709251980.552
spindle organizationGO:00070512530.545
negative regulation of cellular metabolic processGO:00313243820.492
axonogenesisGO:00074092900.467
negative regulation of response to stimulusGO:00485852580.458
catabolic processGO:00090564090.445
Yeast
gland morphogenesisGO:00226121450.424
cell growthGO:00160491080.393
cellular catabolic processGO:00442483720.391
Yeast
mitotic nuclear divisionGO:00070672130.389
rna processingGO:00063961470.375
chemotaxisGO:00069352490.366
vesicle mediated transportGO:00161923810.353
germarium derived egg chamber formationGO:00072931010.343
developmental programmed cell deathGO:00106231380.337
mitotic spindle organizationGO:00070522200.336
regulation of growthGO:00400082330.335
negative regulation of signal transductionGO:00099682060.319
endocytosisGO:00068973100.314
negative regulation of apoptotic processGO:0043066630.306
establishment of organelle localizationGO:00516561220.304
axon guidanceGO:00074112330.276
regulation of apoptotic processGO:00429811300.272
regulation of cell differentiationGO:00455953020.249
regulation of protein metabolic processGO:00512462560.247
enzyme linked receptor protein signaling pathwayGO:00071671790.244
establishment of localization in cellGO:00516494020.212
pole plasm mrna localizationGO:0019094490.205
oocyte constructionGO:00073081120.204
meiotic nuclear divisionGO:00071261510.193
salivary gland developmentGO:00074311620.188
reproductive structure developmentGO:0048608740.187
regulation of cell growthGO:0001558430.185
regulation of cell deathGO:00109411730.183
determination of adult lifespanGO:00083401370.183
Worm
positive regulation of response to stimulusGO:00485843230.174
positive regulation of macromolecule metabolic processGO:00106044050.173
nucleobase containing compound catabolic processGO:00346551650.164
Yeast
meiotic cell cycleGO:00513211710.162
regulation of programmed cell deathGO:00430671520.154
developmental maturationGO:00217001720.152
embryonic development via the syncytial blastodermGO:00017001480.151
oocyte axis specificationGO:00073091080.151
tissue deathGO:00162711020.150
centrosome duplicationGO:00512981210.145
salivary gland cell autophagic cell deathGO:0035071830.134
ribonucleoprotein complex subunit organizationGO:0071826280.132
regulation of organ morphogenesisGO:2000027780.129
salivary gland histolysisGO:0035070880.129
mrna metabolic processGO:00160711240.125
gland developmentGO:00487321910.124
cardiovascular system developmentGO:0072358820.116
taxisGO:00423303040.116
positive regulation of translationGO:0045727120.114
microtubule organizing center organizationGO:00310231680.110
morphogenesis of an epitheliumGO:00020092760.107
muscle structure developmentGO:00610612240.103
cellular macromolecule catabolic processGO:00442651360.103
establishment or maintenance of cell polarityGO:00071631670.100
modification dependent macromolecule catabolic processGO:0043632790.099
guanosine containing compound metabolic processGO:1901068740.098
proteolysisGO:00065081920.097
organic substance catabolic processGO:19015753080.096
Yeast
positive regulation of nucleobase containing compound metabolic processGO:00459353320.096
larval developmentGO:00021641040.094
Worm
rna catabolic processGO:0006401370.094
regulation of organelle organizationGO:00330431960.092
regulation of translationGO:0006417560.091
response to biotic stimulusGO:00096072940.090
centrosome organizationGO:00512971630.088
gastrulationGO:0007369700.086
positive regulation of signalingGO:00230562430.086
autophagic cell deathGO:0048102830.084
negative regulation of intracellular signal transductionGO:1902532570.084
positive regulation of protein metabolic processGO:00512471280.082
negative regulation of programmed cell deathGO:0043069720.081
neuron projection guidanceGO:00974852410.081
cell motilityGO:00488702510.080
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.079
embryonic morphogenesisGO:00485982060.078
negative regulation of cell communicationGO:00106482230.077
forebrain developmentGO:003090020.077
cellular macromolecule localizationGO:00707272200.076
centrosome cycleGO:00070981370.074
negative regulation of cell deathGO:0060548810.074
cell divisionGO:00513012480.073
cell fate determinationGO:0001709910.073
autophagyGO:00069141080.073
positive regulation of signal transductionGO:00099672230.073
nitrogen compound transportGO:0071705850.073
anterior posterior pattern specificationGO:00099521360.072
regulation of multicellular organismal developmentGO:20000264140.072
negative regulation of nitrogen compound metabolic processGO:00511722650.071
embryonic axis specificationGO:00005781070.071
regulation of cellular localizationGO:00603411360.070
regulation of cellular ketone metabolic processGO:001056530.070
sex differentiationGO:0007548810.069
signal transduction by phosphorylationGO:00230141070.068
translational elongationGO:000641440.068
anterior posterior axis specification embryoGO:00085951030.068
appendage morphogenesisGO:00351073970.067
regionalizationGO:00030024160.067
regulation of catabolic processGO:00098941700.067
positive regulation of nitrogen compound metabolic processGO:00511733540.066
hemopoiesisGO:0030097460.066
regulation of endopeptidase activityGO:0052548360.066
cellular nitrogen compound catabolic processGO:00442701650.065
Yeast
positive regulation of cell migrationGO:003033520.065
spindle assemblyGO:0051225800.065
regulation of cell cycleGO:00517262910.064
nucleotide metabolic processGO:00091171610.063
Yeast
chromosome organizationGO:00512763600.063
chromosome segregationGO:00070591570.062
biological adhesionGO:00226101380.062
regulation of mitotic cell cycleGO:00073461900.061
negative regulation of growthGO:0045926840.060
negative regulation of gene expressionGO:00106293870.059
single organismal cell cell adhesionGO:0016337450.059
dna replicationGO:0006260480.059
heterocycle catabolic processGO:00467001660.058
Yeast
organonitrogen compound metabolic processGO:19015643180.058
Yeast
body morphogenesisGO:001017120.058
organic cyclic compound catabolic processGO:19013611680.057
Yeast
developmental growthGO:00485892800.057
appendage developmentGO:00487364010.056
agingGO:00075681430.056
Worm
regulation of transcription from rna polymerase ii promoterGO:00063573780.056
positive regulation of macromolecule biosynthetic processGO:00105572830.055
maintenance of locationGO:0051235730.055
Worm
germarium derived oocyte differentiationGO:0030706290.054
dorsal ventral axis specificationGO:0009950660.053
microtubule cytoskeleton organization involved in mitosisGO:1902850520.052
regulation of endocytosisGO:0030100370.051
embryonic pattern specificationGO:00098801740.051
axis specificationGO:00097981670.050
morphogenesis of follicular epitheliumGO:0016333360.050
positive regulation of developmental growthGO:0048639620.050
positive regulation of cellular protein metabolic processGO:00322701180.050
epithelial cell migrationGO:00106311480.049
macromolecule catabolic processGO:00090571610.049
regulation of cysteine type endopeptidase activityGO:2000116270.047
positive regulation of cell deathGO:0010942690.047
rna localizationGO:00064031150.046
positive regulation of biosynthetic processGO:00098913160.044
positive regulation of developmental processGO:00510941430.044
positive regulation of cellular catabolic processGO:0031331950.044
regulation of nuclear divisionGO:0051783580.043
neurological system processGO:00508773580.043
mapk cascadeGO:00001651070.042
modification dependent protein catabolic processGO:0019941780.041
nucleobase containing small molecule metabolic processGO:00550861740.041
Yeast
ribonucleoprotein complex assemblyGO:0022618230.040
positive regulation of multicellular organismal processGO:00512401430.039
head developmentGO:00603221350.039
positive regulation of programmed cell deathGO:0043068620.038
actin cytoskeleton organizationGO:00300362060.037
small molecule metabolic processGO:00442813050.037
Yeast
response to monosaccharideGO:003428440.037
intracellular signal transductionGO:00355563000.036
single organism biosynthetic processGO:00447112060.036
tissue morphogenesisGO:00487292970.036
nucleus organizationGO:0006997450.036
cellular response to oxygen containing compoundGO:1901701790.036
photoreceptor cell differentiationGO:00465301700.036
cell proliferationGO:00082832990.036
homeostatic processGO:00425921990.036
single organism cellular localizationGO:19025801800.036
brain developmentGO:00074201200.035
cell recognitionGO:00080371020.035
regulation of cellular component biogenesisGO:00440872010.034
positive regulation of nucleic acid templated transcriptionGO:19035082660.034
mrna catabolic processGO:0006402330.034
cellular homeostasisGO:0019725800.034
positive regulation of cell motilityGO:200014730.034
detection of stimulusGO:00516061560.033
actin filament based processGO:00300292200.033
negative regulation of macromolecule biosynthetic processGO:00105582700.033
purine nucleoside metabolic processGO:00422781270.033
Yeast
ribonucleoside catabolic processGO:00424541120.032
Yeast
imaginal disc derived wing morphogenesisGO:00074763370.032
detection of external stimulusGO:0009581660.032
male gamete generationGO:00482322010.032
regulation of localizationGO:00328792750.031
gene silencingGO:00164581380.031
cognitionGO:00508901410.031
single organism intracellular transportGO:19025822070.030
cell maturationGO:00484691440.030
regulation of mitotic cell cycle phase transitionGO:19019901300.030
localization of cellGO:00516742570.030
organic substance transportGO:00717022570.030
cellular metal ion homeostasisGO:0006875310.028
digestive tract developmentGO:00485651490.028
aromatic compound catabolic processGO:00194391660.028
Yeast
spindle assembly involved in mitosisGO:0090307500.028
open tracheal system developmentGO:00074242040.028
cellular protein localizationGO:00346131600.027
fertilizationGO:0009566260.027
positive regulation of cell communicationGO:00106472500.027
negative regulation of developmental processGO:00510932010.027
cellular response to heatGO:0034605240.027
pronuclear migrationGO:003504640.027
nucleoside phosphate metabolic processGO:00067531620.027
Yeast
regulation of rna splicingGO:0043484690.027
cell cycle checkpointGO:0000075950.027
nucleoside metabolic processGO:00091161270.027
Yeast
phosphorylationGO:00163102940.027
intracellular transportGO:00469072280.026
regulation of cellular protein metabolic processGO:00322682430.026
positive regulation of proteolysisGO:0045862520.026
cytoplasmic transport nurse cell to oocyteGO:0007303120.026
regulation of phosphorylationGO:00423251470.026
negative regulation of nucleobase containing compound metabolic processGO:00459342610.026
regulation of cell cycle phase transitionGO:19019871300.026
regulation of response to external stimulusGO:00321011150.026
immune system processGO:00023763470.026
posttranscriptional regulation of gene expressionGO:00106081450.025
regulation of immune system processGO:00026821760.025
phagocytosisGO:00069092150.025
dendrite morphogenesisGO:00488131990.025
meiotic cell cycle processGO:19030461320.025
eye developmentGO:00016543230.025
regulation of catalytic activityGO:00507901850.025
cell adhesionGO:00071551360.025
regulation of cellular catabolic processGO:00313291570.024
imaginal disc derived appendage morphogenesisGO:00351143950.024
regulation of response to stressGO:00801342000.024
segmentationGO:00352822070.024
positive regulation of growthGO:0045927750.024
regulation of molecular functionGO:00650092170.023
sister chromatid segregationGO:0000819920.023
ribonucleoprotein complex biogenesisGO:0022613310.023
macromolecular complex assemblyGO:00650032560.023
purine nucleoside triphosphate metabolic processGO:00091441190.023
Yeast
post embryonic appendage morphogenesisGO:00351203850.022
neuron recognitionGO:00080381010.022
oocyte microtubule cytoskeleton organizationGO:0016325350.022
central nervous system developmentGO:00074172010.022
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.022
tripartite regional subdivisionGO:00073511030.022
cytokinesisGO:0000910900.022
cellular response to dna damage stimulusGO:00069742230.022
single organism catabolic processGO:00447122280.022
Yeast
microtubule based transportGO:0010970420.022
positive regulation of apoptotic processGO:0043065470.021
cellular ketone metabolic processGO:0042180240.021
negative regulation of biosynthetic processGO:00098902770.021
reproductive system developmentGO:0061458740.021
positive regulation of phosphate metabolic processGO:00459371390.021
camera type eye developmentGO:004301040.021
positive regulation of phosphorus metabolic processGO:00105621390.020
digestive system developmentGO:00551231490.020
digestive tract morphogenesisGO:00485461270.020
nuclear transcribed mrna catabolic processGO:0000956240.020
regulation of behaviorGO:0050795750.020
maintenance of protein location in cellGO:0032507260.020
motor neuron axon guidanceGO:0008045580.020
regulation of mapk cascadeGO:0043408920.020
glycosyl compound metabolic processGO:19016571270.020
Yeast
positive regulation of rna biosynthetic processGO:19026802660.020
proteolysis involved in cellular protein catabolic processGO:0051603830.019
dendrite developmentGO:00163582040.019
establishment of cell polarityGO:0030010400.019
ameboidal type cell migrationGO:00016671510.019
positive regulation of rna metabolic processGO:00512542710.019
establishment of rna localizationGO:0051236470.019
double strand break repairGO:0006302260.019
convergent extensionGO:006002620.019
meiotic cytokinesisGO:0033206330.019
regulation of intracellular signal transductionGO:19025312360.019
mitotic spindle elongationGO:0000022810.018
muscle organ developmentGO:00075171270.018
negative regulation of cellular biosynthetic processGO:00313272770.018
instar larval developmentGO:0002168550.018
dorsal ventral pattern formationGO:00099531330.018
regulation of ras protein signal transductionGO:0046578930.018
multicellular organismal agingGO:00102591400.018
Worm
positive regulation of cellular component organizationGO:00511301560.018
mitotic cell cycle phase transitionGO:00447721380.018
regulation of developmental growthGO:00486381740.018
regulation of cell proliferationGO:00421271630.018
positive regulation of hydrolase activityGO:0051345780.018
oocyte dorsal ventral axis specificationGO:0007310340.018
cellular response to lipidGO:0071396200.018
negative regulation of cell cycle processGO:00109481090.017
purine ribonucleoside metabolic processGO:00461281270.017
Yeast
gonad developmentGO:0008406500.017
nucleoside triphosphate metabolic processGO:00091411200.017
Yeast
nuclear transportGO:0051169720.017
autophagic vacuole assemblyGO:000004520.017
nucleoside biosynthetic processGO:000916330.017
spermatogenesisGO:00072832000.017
cytoplasmic transportGO:00164821300.017
anterior posterior axis specificationGO:00099481090.017
intracellular mrna localization involved in anterior posterior axis specificationGO:0060811530.017
purine ribonucleotide metabolic processGO:00091501450.016
Yeast
developmental cell growthGO:0048588520.016
organelle localizationGO:00516401480.016
purine nucleoside biosynthetic processGO:004245130.016
spermatid differentiationGO:00485151140.016
regulation of cell projection organizationGO:0031344920.016
gene silencing by rnaGO:0031047570.016
pole plasm assemblyGO:0007315610.016
rna interferenceGO:0016246270.016
cellular macromolecular complex assemblyGO:00346221530.016
negative regulation of translationGO:0017148280.016
nucleotide catabolic processGO:00091661090.015
Yeast
development of primary sexual characteristicsGO:0045137500.015
ribosomal large subunit biogenesisGO:004227310.015
negative regulation of protein metabolic processGO:0051248850.015
nucleobase containing compound transportGO:0015931560.015
regulation of proteolysisGO:0030162870.015
ribonucleoside monophosphate biosynthetic processGO:000915630.015
regulation of notch signaling pathwayGO:00085931000.015
regulation of mitosisGO:0007088560.015
regulation of phosphatase activityGO:001092130.015
cellularizationGO:0007349900.015
imaginal disc derived appendage developmentGO:00487373990.015
negative regulation of mitotic cell cycle phase transitionGO:19019911030.015
larval midgut cell programmed cell deathGO:0035096190.015
response to hexoseGO:000974630.015
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.015
response to oxygen containing compoundGO:19017002000.014
regulation of anatomical structure morphogenesisGO:00226032420.014
cuticle developmentGO:0042335860.014
regulation of neurogenesisGO:00507671580.014
oxoacid metabolic processGO:00434361030.014
retina development in camera type eyeGO:006004140.014
actomyosin structure organizationGO:0031032560.014
chemical homeostasisGO:0048878920.014
receptor mediated endocytosisGO:0006898210.014
negative regulation of multicellular organismal processGO:00512411420.014
positive regulation of transcription dna templatedGO:00458932660.014
negative regulation of catalytic activityGO:0043086420.014
negative regulation of molecular functionGO:0044092510.014
substrate adhesion dependent cell spreadingGO:003444620.014
detection of abiotic stimulusGO:0009582660.013
negative regulation of cell cycle phase transitionGO:19019881030.013
oocyte microtubule cytoskeleton polarizationGO:0008103220.013
purine containing compound catabolic processGO:00725231120.013
Yeast
proteasomal protein catabolic processGO:0010498590.013
positive regulation of cell differentiationGO:0045597640.013
cell migrationGO:00164772380.013
germarium derived oocyte fate determinationGO:0007294260.013
negative regulation of cellular protein metabolic processGO:0032269850.013
cellular protein catabolic processGO:0044257830.013
carbohydrate derivative metabolic processGO:19011352170.013
Yeast
circulatory system developmentGO:0072359820.013
ribonucleotide catabolic processGO:00092611090.013
Yeast
rna transportGO:0050658460.013
respiratory system developmentGO:00605412130.012
carbohydrate homeostasisGO:0033500120.012
notch signaling pathwayGO:00072191200.012
positive regulation of molecular functionGO:00440931360.012
nuclear exportGO:0051168240.012
stem cell divisionGO:0017145690.012
purine ribonucleoside triphosphate catabolic processGO:00092071080.012
Yeast
ribonucleoside metabolic processGO:00091191270.012
Yeast
purine containing compound metabolic processGO:00725211550.012
Yeast
protein localizationGO:00081042840.012
response to organic substanceGO:00100332840.012
ribonucleoside triphosphate metabolic processGO:00091991190.012
Yeast
response to ecdysoneGO:0035075340.012
nucleoside triphosphate catabolic processGO:00091431080.012
Yeast
regulation of cell developmentGO:00602842150.012
negative regulation of transcription dna templatedGO:00458922370.012
negative regulation of mapk cascadeGO:0043409230.012
oocyte fate determinationGO:0030716270.012
dorsal closureGO:0007391790.012
protein catabolic processGO:00301631010.011
carbohydrate metabolic processGO:0005975820.011
regulation of neuron projection developmentGO:0010975690.011
regulation of cellular response to stressGO:0080135890.011
mesoderm developmentGO:0007498780.011
purine ribonucleotide catabolic processGO:00091541090.011
Yeast
response to other organismGO:00517072930.011
chromatin silencingGO:0006342760.011
positive regulation of protein catabolic processGO:0045732340.011
axon extensionGO:0048675320.011
maintenance of protein locationGO:0045185280.011
protein modification processGO:00362114380.011
positive regulation of phosphorylationGO:0042327870.011
regulation of hydrolase activityGO:0051336970.011
response to heatGO:0009408630.011
single fertilizationGO:0007338240.011
axon cargo transportGO:0008088290.011
heart morphogenesisGO:0003007320.011
regulation of mrna metabolic processGO:1903311720.010
purine nucleotide catabolic processGO:00061951090.010
Yeast
regulation of stress activated protein kinase signaling cascadeGO:0070302420.010
cell type specific apoptotic processGO:0097285380.010
stem cell developmentGO:0048864790.010
positive regulation of erk1 and erk2 cascadeGO:0070374360.010
convergent extension involved in gastrulationGO:006002720.010

eIF-4a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org