IMP: Integrative Multi-species Prediction

Drosophila melanogaster

32 known processes

RpS11 (Dmel_CG8857)

Ribosomal protein S11

(Aliases: M(2)48E,clone 23,anon-MMS23,Dmel\CG8857,S11,CG8857,anon-EST:fe1D2)

Entrez: 36321
FLYBASE: FBgn0033699
UniProtKB: Q0E9B6
UniProtKB: A1Z8U9

Process Predictions
Disease Predictions

RpS11 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability	Func Analog Org
mitotic spindle elongation	GO:0000022	81	0.996
mitotic spindle organization	GO:0007052	220	0.963
spindle elongation	GO:0051231	83	0.935
spindle organization	GO:0007051	253	0.930
centrosome organization	GO:0051297	163	0.733
centrosome duplication	GO:0051298	121	0.720
larval development	GO:0002164	104	0.446
centrosome cycle	GO:0007098	137	0.444
microtubule organizing center organization	GO:0031023	168	0.367
embryo development ending in birth or egg hatching	GO:0009792	152	0.248
death	GO:0016265	284	0.244
mitotic dna integrity checkpoint	GO:0044774	75	0.173
vesicle mediated transport	GO:0016192	381	0.127
programmed cell death	GO:0012501	257	0.114
cell death	GO:0008219	279	0.113
apoptotic process	GO:0006915	159	0.107
rna processing	GO:0006396	147	0.099	Yeast
organelle assembly	GO:0070925	198	0.095	Yeast
multicellular organismal aging	GO:0010259	140	0.087
molting cycle	GO:0042303	56	0.085
regulation of cell cycle	GO:0051726	291	0.078
endocytosis	GO:0006897	310	0.068
ribosomal large subunit biogenesis	GO:0042273	1	0.063
rrna processing	GO:0006364	3	0.059	Yeast
regulation of phosphorylation	GO:0042325	147	0.054
reproductive system development	GO:0061458	74	0.051
signal transduction by phosphorylation	GO:0023014	107	0.042
regulation of phosphate metabolic process	GO:0019220	210	0.042
regulation of growth	GO:0040008	233	0.042
immune system process	GO:0002376	347	0.040
gonad development	GO:0008406	50	0.039
body morphogenesis	GO:0010171	2	0.038
dna integrity checkpoint	GO:0031570	81	0.036
exocrine system development	GO:0035272	162	0.036
macromolecular complex assembly	GO:0065003	256	0.035	Yeast
establishment of localization in cell	GO:0051649	402	0.035
response to biotic stimulus	GO:0009607	294	0.034
rna localization	GO:0006403	115	0.034
organic substance transport	GO:0071702	257	0.033
dna damage checkpoint	GO:0000077	78	0.032
regulation of multicellular organism growth	GO:0040014	40	0.032
regulation of protein modification process	GO:0031399	112	0.032
phagocytosis	GO:0006909	215	0.032
regulation of cellular protein metabolic process	GO:0032268	243	0.031
positive regulation of phosphorylation	GO:0042327	87	0.031
regulation of phosphorus metabolic process	GO:0051174	210	0.031
negative regulation of phosphatase activity	GO:0010923	3	0.030
ras protein signal transduction	GO:0007265	88	0.029
epithelial cell development	GO:0002064	274	0.028
positive regulation of phosphate metabolic process	GO:0045937	139	0.028
sex differentiation	GO:0007548	81	0.027
determination of adult lifespan	GO:0008340	137	0.027
negative regulation of cell cycle process	GO:0010948	109	0.026
translation	GO:0006412	69	0.026
cell proliferation	GO:0008283	299	0.025
defense response	GO:0006952	300	0.025
cellular macromolecular complex assembly	GO:0034622	153	0.025	Yeast
negative regulation of cell cycle	GO:0045786	116	0.024
positive regulation of response to stimulus	GO:0048584	323	0.023
protein modification process	GO:0036211	438	0.023
regulation of mapk cascade	GO:0043408	92	0.023
mitotic dna damage checkpoint	GO:0044773	74	0.023
positive regulation of biosynthetic process	GO:0009891	316	0.022
positive regulation of phosphorus metabolic process	GO:0010562	139	0.021
cellular protein modification process	GO:0006464	438	0.021
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.021
growth	GO:0040007	359	0.021
protein localization	GO:0008104	284	0.020
regulation of cell death	GO:0010941	173	0.020
response to other organism	GO:0051707	293	0.020
positive regulation of signaling	GO:0023056	243	0.020
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.020
aging	GO:0007568	143	0.019
regulation of molecular function	GO:0065009	217	0.019
phosphorylation	GO:0016310	294	0.018
regulation of developmental growth	GO:0048638	174	0.018
defense response to other organism	GO:0098542	225	0.018
posttranscriptional regulation of gene expression	GO:0010608	145	0.018
positive regulation of catalytic activity	GO:0043085	118	0.018
cell recognition	GO:0008037	102	0.018
nucleobase containing compound transport	GO:0015931	56	0.017
cell cycle checkpoint	GO:0000075	95	0.017
negative regulation of gene expression	GO:0010629	387	0.017
regulation of protein metabolic process	GO:0051246	256	0.017
ncrna processing	GO:0034470	30	0.017	Yeast
regulation of multicellular organismal development	GO:2000026	414	0.017
regulation of catalytic activity	GO:0050790	185	0.017
nuclear transport	GO:0051169	72	0.016
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.016
negative regulation of mitotic cell cycle	GO:0045930	109	0.016
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.016
negative regulation of cellular protein metabolic process	GO:0032269	85	0.016
positive regulation of gene expression	GO:0010628	290	0.016
positive regulation of cell communication	GO:0010647	250	0.016
mitotic cell cycle phase transition	GO:0044772	138	0.015
developmental programmed cell death	GO:0010623	138	0.015
defense response to bacterium	GO:0042742	178	0.015
positive regulation of macromolecule metabolic process	GO:0010604	405	0.015
reproductive structure development	GO:0048608	74	0.015
ribonucleoprotein complex biogenesis	GO:0022613	31	0.015	Yeast
eye development	GO:0001654	323	0.014
mapk cascade	GO:0000165	107	0.014
positive regulation of intracellular signal transduction	GO:1902533	116	0.014
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.014
axon development	GO:0061564	297	0.013
small gtpase mediated signal transduction	GO:0007264	88	0.013
gland morphogenesis	GO:0022612	145	0.013
negative regulation of biosynthetic process	GO:0009890	277	0.013
positive regulation of molecular function	GO:0044093	136	0.013
positive regulation of developmental process	GO:0051094	143	0.013
positive regulation of growth	GO:0045927	75	0.012
positive regulation of mapk cascade	GO:0043410	63	0.012
cytoplasmic transport	GO:0016482	130	0.012
cell migration	GO:0016477	238	0.012
central nervous system development	GO:0007417	201	0.012
multicellular organism growth	GO:0035264	46	0.012
intracellular signal transduction	GO:0035556	300	0.012
positive regulation of catabolic process	GO:0009896	105	0.012
genitalia development	GO:0048806	26	0.012
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.011
spermatid differentiation	GO:0048515	114	0.011
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.011
regulation of hemocyte proliferation	GO:0035206	37	0.011
organonitrogen compound metabolic process	GO:1901564	318	0.011
single organism biosynthetic process	GO:0044711	206	0.011
rna transport	GO:0050658	46	0.011
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.011
positive regulation of signal transduction	GO:0009967	223	0.011
negative regulation of protein metabolic process	GO:0051248	85	0.011
regulation of apoptotic process	GO:0042981	130	0.011
nitrogen compound transport	GO:0071705	85	0.011
jnk cascade	GO:0007254	50	0.011
mitotic cell cycle checkpoint	GO:0007093	88	0.010
response to bacterium	GO:0009617	198	0.010
regulation of cell cycle phase transition	GO:1901987	130	0.010
regulation of mitotic cell cycle	GO:0007346	190	0.010

RpS11 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.020
hematopoietic system disease	DOID:74	0.012
immune system disease	DOID:2914	0.012
bone marrow disease	DOID:4961	0.012
aplastic anemia	DOID:12449	0.012
anemia	DOID:2355	0.012

Loading network...

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network