Drosophila melanogaster

0 known processes

Hsc70-1 (Dmel_CG8937)

Heat shock protein cognate 1

(Aliases: Hsc70,dhsc70-1,143191_at,hsc70,HSC70,BcDNA:RH49358,CG8937,dhsc70,Hsc1,HSC1,HSC-70,Dmel\CG8937)

Hsc70-1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to abiotic stimulusGO:00096283410.060
Human Yeast Rat
chromosome organizationGO:00512763600.056
Mouse
multicellular organismal agingGO:00102591400.048
response to organic substanceGO:00100332840.047
Human Rat Fly
eye morphogenesisGO:00485922600.042
regulation of multicellular organismal developmentGO:20000264140.040
Human Rat
agingGO:00075681430.040
determination of adult lifespanGO:00083401370.039
cell cell signaling involved in cell fate commitmentGO:00451682100.038
vesicle mediated transportGO:00161923810.036
Yeast Mouse Fly
cellular response to heatGO:0034605240.036
Human Yeast
deathGO:00162652840.035
Human Rat
response to external biotic stimulusGO:00432072930.034
endocytosisGO:00068973100.034
cellular protein modification processGO:00064644380.032
Human Mouse
response to biotic stimulusGO:00096072940.031
imaginal disc derived appendage morphogenesisGO:00351143950.031
response to heatGO:0009408630.031
Human Yeast
response to lipopolysaccharideGO:003249640.030
phagocytosisGO:00069092150.030
single organism behaviorGO:00447083910.030
protein modification processGO:00362114380.030
Human Mouse
compound eye developmentGO:00487493070.030
eye developmentGO:00016543230.030
organonitrogen compound metabolic processGO:19015643180.029
Human Yeast Mouse Rat
immune system processGO:00023763470.029
Human Rat
cellular catabolic processGO:00442483720.029
Human Yeast Mouse Rat
lateral inhibitionGO:00463312060.028
photoreceptor cell differentiationGO:00465301700.028
catabolic processGO:00090564090.028
Human Yeast Mouse Rat
compound eye morphogenesisGO:00017452490.028
kidney developmentGO:000182230.028
response to nutrient levelsGO:00316671140.028
sensory organ morphogenesisGO:00905962600.028
positive regulation of response to stimulusGO:00485843230.027
Rat
response to endogenous stimulusGO:00097191190.027
imaginal disc derived appendage developmentGO:00487373990.027
proteolysisGO:00065081920.027
Yeast Rat
response to other organismGO:00517072930.026
transcription from rna polymerase ii promoterGO:00063663680.026
body morphogenesisGO:001017120.026
forebrain developmentGO:003090020.026
response to nitrogen compoundGO:1901698900.025
appendage developmentGO:00487364010.025
regionalizationGO:00030024160.025
cellular response to chemical stimulusGO:00708871990.025
Fly
organic substance catabolic processGO:19015753080.025
Human Yeast Mouse Rat
wing disc morphogenesisGO:00074723440.025
negative regulation of biosynthetic processGO:00098902770.025
Human
small molecule metabolic processGO:00442813050.025
Human Yeast Mouse Rat
taxisGO:00423303040.025
Fly
imaginal disc derived wing morphogenesisGO:00074763370.024
regulation of cell cycleGO:00517262910.024
Mouse
intracellular signal transductionGO:00355563000.024
epithelial cell differentiationGO:00308553220.023
negative regulation of cellular metabolic processGO:00313243820.023
Human Rat
gland developmentGO:00487321910.023
organic substance transportGO:00717022570.023
Yeast
spermatogenesisGO:00072832000.023
Mouse
neurological system processGO:00508773580.023
regulation of cell differentiationGO:00455953020.023
Human Rat
segmentationGO:00352822070.023
regulation of localizationGO:00328792750.023
appendage morphogenesisGO:00351073970.022
positive regulation of macromolecule metabolic processGO:00106044050.022
Mouse
defense responseGO:00069523000.022
Rat
response to oxygen containing compoundGO:19017002000.022
Rat
spindle organizationGO:00070512530.022
negative regulation of gene expressionGO:00106293870.022
Human Rat Fly
regulation of cellular protein metabolic processGO:00322682430.022
Human Mouse Rat
post embryonic appendage morphogenesisGO:00351203850.022
eye photoreceptor cell differentiationGO:00017541450.022
oxoacid metabolic processGO:00434361030.021
connective tissue developmentGO:006144830.021
programmed cell deathGO:00125012570.021
Human Rat
heterocycle catabolic processGO:00467001660.021
Human Yeast Mouse Rat
regulation of transcription from rna polymerase ii promoterGO:00063573780.021
regulation of protein metabolic processGO:00512462560.021
Human Mouse Rat
macromolecule catabolic processGO:00090571610.021
Human Yeast
nuclear divisionGO:00002803320.021
Mouse
positive regulation of cell communicationGO:00106472500.021
nucleobase containing compound catabolic processGO:00346551650.020
Human Yeast Mouse Rat
positive regulation of cellular biosynthetic processGO:00313283160.020
regulation of anatomical structure morphogenesisGO:00226032420.020
organelle fissionGO:00482853400.020
Mouse
aromatic compound catabolic processGO:00194391660.020
Human Yeast Mouse Rat
localization of cellGO:00516742570.020
regulation of intracellular signal transductionGO:19025312360.020
positive regulation of nucleobase containing compound metabolic processGO:00459353320.020
Mouse
phosphorylationGO:00163102940.020
Mouse
cellular macromolecule catabolic processGO:00442651360.020
Human Yeast
negative regulation of nucleobase containing compound metabolic processGO:00459342610.020
Human
regulation of response to stressGO:00801342000.020
negative regulation of developmental processGO:00510932010.020
response to organonitrogen compoundGO:0010243750.020
regulation of cellular ketone metabolic processGO:001056530.020
developmental growthGO:00485892800.020
detection of stimulusGO:00516061560.020
response to organic cyclic compoundGO:0014070890.019
cellular amine metabolic processGO:0044106120.019
response to organophosphorusGO:004668320.019
negative regulation of response to stimulusGO:00485852580.019
Human
respiratory system developmentGO:00605412130.019
cellular ketone metabolic processGO:0042180240.019
posttranscriptional regulation of gene expressionGO:00106081450.019
Fly
carbohydrate derivative metabolic processGO:19011352170.019
Human Yeast Mouse Rat
cell deathGO:00082192790.019
Human Rat
cholesterol transportGO:003030120.019
sensory perceptionGO:00076001960.019
protein localizationGO:00081042840.019
Yeast
positive regulation of nitrogen compound metabolic processGO:00511733540.019
Mouse
regulation of mitotic cell cycleGO:00073461900.019
epithelial cell developmentGO:00020642740.019
immune response regulating signaling pathwayGO:000276420.019
immune effector processGO:0002252980.019
Rat
negative regulation of rna metabolic processGO:00512532510.019
Human
immune responseGO:00069552460.019
Rat
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.019
Human
regulation of cell deathGO:00109411730.019
Human Rat
lipopolysaccharide mediated signaling pathwayGO:003166310.018
positive regulation of signalingGO:00230562430.018
cell cycle phase transitionGO:00447701400.018
Mouse
organic acid metabolic processGO:00060821030.018
open tracheal system developmentGO:00074242040.018
axis specificationGO:00097981670.018
actin cytoskeleton organizationGO:00300362060.018
response to extracellular stimulusGO:00099911160.018
mitotic cell cycle phase transitionGO:00447721380.018
Mouse
cell migrationGO:00164772380.018
compound eye photoreceptor cell differentiationGO:00017511400.018
negative regulation of signal transductionGO:00099682060.018
Human
embryonic pattern specificationGO:00098801740.018
tissue deathGO:00162711020.017
response to radiationGO:00093141550.017
Rat
cellular amino acid metabolic processGO:0006520610.017
regulation of cellular amino acid metabolic processGO:000652100.017
response to bacteriumGO:00096171980.017
centrosome organizationGO:00512971630.017
single organism catabolic processGO:00447122280.017
Human Yeast Mouse Rat
chromatin organizationGO:00063252070.017
cellular macromolecule localizationGO:00707272200.017
Yeast
blastoderm segmentationGO:00073501590.017
macromolecular complex assemblyGO:00650032560.017
organic cyclic compound catabolic processGO:19013611680.017
Human Yeast Mouse Rat
growthGO:00400073590.017
Human
actin filament based processGO:00300292200.017
regulation of cellular amine metabolic processGO:003323830.017
rna localizationGO:00064031150.017
positive regulation of signal transductionGO:00099672230.017
actin filament organizationGO:00070151260.017
single organism intracellular transportGO:19025822070.017
Yeast
androgen metabolic processGO:000820910.017
cell motilityGO:00488702510.016
amine metabolic processGO:0009308120.016
detection of abiotic stimulusGO:0009582660.016
columnar cuboidal epithelial cell developmentGO:00020662490.016
cell divisionGO:00513012480.016
photoreceptor cell developmentGO:0042461960.016
hormone catabolic processGO:004244730.016
dendrite morphogenesisGO:00488131990.016
positive regulation of transcription dna templatedGO:00458932660.016
cellular response to dna damage stimulusGO:00069742230.016
positive regulation of macromolecule biosynthetic processGO:00105572830.016
salivary gland morphogenesisGO:00074351450.016
rna processingGO:00063961470.016
Mouse
negative regulation of signalingGO:00230572190.016
Human
dendrite developmentGO:00163582040.016
regulation of cellular catabolic processGO:00313291570.016
cellular response to organic substanceGO:00713101320.016
Fly
regulation of catabolic processGO:00098941700.016
intracellular transportGO:00469072280.016
Yeast
cellular nitrogen compound catabolic processGO:00442701650.016
Human Yeast Mouse Rat
pigment metabolic processGO:0042440840.016
cell proliferationGO:00082832990.016
Human
regulation of molecular functionGO:00650092170.016
Mouse Rat
mitotic nuclear divisionGO:00070672130.016
maintenance of locationGO:0051235730.016
columnar cuboidal epithelial cell differentiationGO:00020652560.016
regulation of nervous system developmentGO:00519602480.016
Rat
negative regulation of macromolecule biosynthetic processGO:00105582700.016
Human
telencephalon developmentGO:002153720.016
biological adhesionGO:00226101380.016
eye photoreceptor cell developmentGO:0042462810.016
positive regulation of biosynthetic processGO:00098913160.016
compound eye photoreceptor developmentGO:0042051780.016
mitotic spindle organizationGO:00070522200.016
microtubule organizing center organizationGO:00310231680.016
morphogenesis of an epitheliumGO:00020092760.016
carboxylic acid metabolic processGO:0019752920.016
exocrine system developmentGO:00352721620.016
immune response activating signal transductionGO:000275720.016
central nervous system developmentGO:00074172010.015
positive regulation of lipid storageGO:001088440.015
establishment of localization in cellGO:00516494020.015
Yeast Fly
negative regulation of nucleic acid templated transcriptionGO:19035072400.015
Human
developmental maturationGO:00217001720.015
single organism biosynthetic processGO:00447112060.015
homeostatic processGO:00425921990.015
Human
embryonic axis specificationGO:00005781070.015
regulation of cellular component biogenesisGO:00440872010.015
Human
regulation of mitotic cell cycle phase transitionGO:19019901300.015
regulation of cell cycle phase transitionGO:19019871300.015
regulation of cell morphogenesisGO:00226041630.015
positive regulation of nucleic acid templated transcriptionGO:19035082660.015
humoral immune responseGO:00069591170.015
regulation of organelle organizationGO:00330431960.015
histolysisGO:00075591020.015
axon developmentGO:00615642970.015
Fly
cellular response to biotic stimulusGO:007121640.015
anterior posterior axis specification embryoGO:00085951030.015
gland morphogenesisGO:00226121450.015
ethanolamine containing compound metabolic processGO:004243940.015
tissue morphogenesisGO:00487292970.015
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.015
organelle assemblyGO:00709251980.015
negative regulation of transcription dna templatedGO:00458922370.014
Human
camera type eye developmentGO:004301040.014
enzyme linked receptor protein signaling pathwayGO:00071671790.014
regulation of phosphorus metabolic processGO:00511742100.014
Mouse
cellular response to lipopolysaccharideGO:007122230.014
regulation of cell cycle processGO:00105641810.014
neuron projection guidanceGO:00974852410.014
Fly
salivary gland developmentGO:00074311620.014
negative regulation of nitrogen compound metabolic processGO:00511722650.014
Human
positive regulation of rna biosynthetic processGO:19026802660.014
endomembrane system organizationGO:00102561190.014
negative regulation of rna biosynthetic processGO:19026792400.014
Human
negative regulation of cell communicationGO:00106482230.014
Human
cholesterol homeostasisGO:004263230.014
tripartite regional subdivisionGO:00073511030.014
regulation of immune system processGO:00026821760.014
Human Rat
regulation of catalytic activityGO:00507901850.014
Mouse Rat
positive regulation of gene expressionGO:00106282900.014
Mouse
positive regulation of catalytic activityGO:00430851180.014
Mouse
regulation of growthGO:00400082330.014
Human
regulation of epithelial cell differentiationGO:003085640.014
response to glucoseGO:000974920.014
anterior posterior pattern specificationGO:00099521360.013
multi organism behaviorGO:00517051750.013
dna metabolic processGO:00062592270.013
defense response to other organismGO:00985422250.013
proteolysis involved in cellular protein catabolic processGO:0051603830.013
Yeast
developmental programmed cell deathGO:00106231380.013
regulation of i kappab kinase nf kappab signalingGO:004312220.013
response to hexoseGO:000974630.013
negative regulation of mitotic cell cycle phase transitionGO:19019911030.013
regulation of cell developmentGO:00602842150.013
Rat
regulation of response to external stimulusGO:00321011150.013
response to oxygen levelsGO:0070482590.013
regulation of anatomical structure sizeGO:00900661630.013
Rat
protein complex assemblyGO:00064612000.013
regulation of phosphorylationGO:00423251470.013
Mouse
positive regulation of molecular functionGO:00440931360.013
Mouse
ovarian follicle cell developmentGO:00307072480.013
axon guidanceGO:00074112330.013
Fly
response to decreased oxygen levelsGO:0036293580.013
adult behaviorGO:00305341370.013
axonogenesisGO:00074092900.013
Fly
antimicrobial humoral responseGO:0019730990.013
synapse assemblyGO:00074161430.013
purine containing compound metabolic processGO:00725211550.013
Human Yeast Mouse Rat
response to light stimulusGO:00094161240.013
chemotaxisGO:00069352490.013
Fly
anterior posterior axis specificationGO:00099481090.013
mrna metabolic processGO:00160711240.013
Human Mouse
male gamete generationGO:00482322010.013
Mouse
innate immune responseGO:00450871440.013
regulation of cellular response to stressGO:0080135890.013
negative regulation of cellular biosynthetic processGO:00313272770.013
Human
regulation of notch signaling pathwayGO:00085931000.013
anion homeostasisGO:005508130.013
negative regulation of cell cycleGO:00457861160.013
purine ribonucleoside catabolic processGO:00461301120.013
Human Yeast Mouse Rat
negative regulation of cell differentiationGO:00455961430.013
response to hypoxiaGO:0001666530.013
negative regulation of cell cycle processGO:00109481090.013
nucleus organizationGO:0006997450.013
positive regulation of cellular amine metabolic processGO:003324000.012
regulation of cellular localizationGO:00603411360.012
steroid catabolic processGO:000670610.012
sensory perception of soundGO:0007605560.012
apoptotic processGO:00069151590.012
Human Rat
cellularizationGO:0007349900.012
salivary gland histolysisGO:0035070880.012
sterol homeostasisGO:005509240.012
pigmentationGO:0043473750.012
negative regulation of cell cycle phase transitionGO:19019881030.012
ameboidal type cell migrationGO:00016671510.012
positive regulation of multicellular organismal processGO:00512401430.012
Human Rat
organonitrogen compound biosynthetic processGO:19015661170.012
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.012
nucleoside phosphate catabolic processGO:19012921100.012
Human Yeast Mouse Rat
small gtpase mediated signal transductionGO:0007264880.012
cytoplasmic transportGO:00164821300.012
Yeast
cell cycle checkpointGO:0000075950.012
organonitrogen compound catabolic processGO:19015651280.012
Human Yeast Mouse Rat
modification dependent macromolecule catabolic processGO:0043632790.012
single organism cellular localizationGO:19025801800.012
Yeast
mitotic cell cycle checkpointGO:0007093880.012
negative regulation of cellular component organizationGO:00511291080.012
Human
regulation of multi organism processGO:00439001310.012
cellular response to abiotic stimulusGO:0071214580.012
hindbrain developmentGO:003090220.012
response to monosaccharideGO:003428440.012
ras protein signal transductionGO:0007265880.012
regulation of developmental growthGO:00486381740.012
positive regulation of phosphate metabolic processGO:00459371390.012
Mouse
notch signaling pathwayGO:00072191200.012
modification dependent protein catabolic processGO:0019941780.012
peptide metabolic processGO:0006518800.012
negative regulation of cell deathGO:0060548810.012
Human Rat
response to acid chemicalGO:0001101250.012
cellular lipid metabolic processGO:0044255830.012
mesenchymal cell developmentGO:001403110.012
autophagic cell deathGO:0048102830.012
nucleotide metabolic processGO:00091171610.012
Human Yeast Mouse Rat
positive regulation of cell migrationGO:003033520.012
positive regulation of cellular amino acid metabolic processGO:004576400.012
dorsal ventral pattern formationGO:00099531330.012
limb morphogenesisGO:003510810.012
detection of external stimulusGO:0009581660.012
sensory perception of mechanical stimulusGO:0050954720.012
protein modification by small protein conjugation or removalGO:00706471060.011
Human
regulation of transportGO:00510491810.011
ribonucleotide metabolic processGO:00092591450.011
Human Yeast Mouse Rat
cellular response to radiationGO:0071478520.011
positive regulation of rna metabolic processGO:00512542710.011
Mouse
cellular protein localizationGO:00346131600.011
Yeast
negative regulation of mitotic cell cycleGO:00459301090.011
positive regulation of cell motilityGO:200014730.011
neuromuscular junction developmentGO:00075281490.011
cellular homeostasisGO:0019725800.011
developmental pigmentationGO:0048066680.011
negative regulation of multicellular organismal processGO:00512411420.011
Rat
signal transduction by phosphorylationGO:00230141070.011
negative regulation of cellular protein metabolic processGO:0032269850.011
Human Rat
positive regulation of phosphorus metabolic processGO:00105621390.011
Mouse
mesenchymal cell differentiationGO:004876210.011
ubiquitin dependent protein catabolic processGO:0006511780.011
covalent chromatin modificationGO:00165691060.011
cellular macromolecular complex assemblyGO:00346221530.011
chromosome segregationGO:00070591570.011
monocarboxylic acid transportGO:001571830.011
limb developmentGO:006017310.011
response to alcoholGO:0097305950.011
Rat
glycosyl compound metabolic processGO:19016571270.011
Human Yeast Mouse Rat
kidney epithelium developmentGO:007207330.011
innate immune response activating signal transductionGO:000275820.011
regulation of defense responseGO:00313471020.011
regulation of cell shapeGO:00083601130.011
nucleobase containing small molecule metabolic processGO:00550861740.011
Human Yeast Mouse Rat
cellular protein catabolic processGO:0044257830.011
Yeast
cell maturationGO:00484691440.011
purine nucleotide metabolic processGO:00061631460.011
Human Yeast Mouse Rat
regulation of apoptotic processGO:00429811300.011
Human Rat
response to temperature stimulusGO:00092661060.011
Human Yeast
vitamin metabolic processGO:000676620.011
locomotory behaviorGO:00076261760.011
xenobiotic catabolic processGO:004217810.011
positive regulation of catabolic processGO:00098961050.011
regulation of cell proliferationGO:00421271630.011
Human
mapk cascadeGO:00001651070.011
regulation of translationGO:0006417560.011
tube morphogenesisGO:00352391910.011
cellular response to oxygen containing compoundGO:1901701790.011
oocyte differentiationGO:00099941450.011
gene silencingGO:00164581380.011
Fly
detection of chemical stimulusGO:0009593930.011
salivary gland cell autophagic cell deathGO:0035071830.011
regulation of programmed cell deathGO:00430671520.011
Human Rat
centrosome cycleGO:00070981370.011
sensory perception of smellGO:0007608800.011
cellular response to molecule of bacterial originGO:007121930.011
positive regulation of cellular catabolic processGO:0031331950.011
dorsal ventral axis specificationGO:0009950660.011
positive regulation of intracellular signal transductionGO:19025331160.011
protein phosphorylationGO:00064681690.011
Mouse
organophosphate metabolic processGO:00196371950.011
Human Yeast Mouse Rat
ribonucleotide catabolic processGO:00092611090.010
Human Yeast Mouse Rat
positive regulation of cellular protein metabolic processGO:00322701180.010
Mouse
brain developmentGO:00074201200.010
synapse organizationGO:00508081960.010
protein transportGO:00150311550.010
Yeast
cellular amide metabolic processGO:0043603800.010
autophagyGO:00069141080.010
ribonucleoside catabolic processGO:00424541120.010
Human Yeast Mouse Rat
embryonic development via the syncytial blastodermGO:00017001480.010
Fly
mrna processingGO:00063971040.010
Mouse
cellular component assembly involved in morphogenesisGO:00109271510.010
ribonucleoside triphosphate catabolic processGO:00092031080.010
Human Yeast Mouse Rat
purine nucleoside catabolic processGO:00061521120.010
Human Yeast Mouse Rat
defense response to bacteriumGO:00427421780.010
purine ribonucleoside triphosphate catabolic processGO:00092071080.010
Human Yeast Mouse Rat
synaptic growth at neuromuscular junctionGO:00511241190.010
protein complex biogenesisGO:00702712010.010
purine ribonucleotide metabolic processGO:00091501450.010
Human Yeast Mouse Rat
purine nucleotide catabolic processGO:00061951090.010
Human Yeast Mouse Rat
negative regulation of programmed cell deathGO:0043069720.010
Human Rat
hematopoietic progenitor cell differentiationGO:000224410.010
positive regulation of developmental processGO:00510941430.010
Human Rat

Hsc70-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.043
nervous system diseaseDOID:86300.020
disease of metabolismDOID:001466700.017
inherited metabolic disorderDOID:65500.013
cancerDOID:16200.012
disease of cellular proliferationDOID:1456600.012
musculoskeletal system diseaseDOID:1700.012
cardiovascular system diseaseDOID:128700.012
glucose metabolism diseaseDOID:419400.010
type 2 diabetes mellitusDOID:935200.010
carbohydrate metabolism diseaseDOID:005001300.010
acquired metabolic diseaseDOID:006015800.010
diabetes mellitusDOID:935100.010
sensory system diseaseDOID:005015500.010
central nervous system diseaseDOID:33100.010