Drosophila melanogaster

19 known processes

tgy (Dmel_CG7440)

twiggy

(Aliases: CG7440,Dmel\CG7440)

tgy biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to bacteriumGO:00096171980.050
regionalizationGO:00030024160.049
catabolic processGO:00090564090.041
response to abiotic stimulusGO:00096283410.040
response to biotic stimulusGO:00096072940.037
positive regulation of nitrogen compound metabolic processGO:00511733540.037
oxoacid metabolic processGO:00434361030.035
imaginal disc derived appendage developmentGO:00487373990.034
response to other organismGO:00517072930.034
response to lipopolysaccharideGO:003249640.033
imaginal disc derived wing morphogenesisGO:00074763370.033
wing disc morphogenesisGO:00074723440.033
response to external biotic stimulusGO:00432072930.032
protein modification processGO:00362114380.032
Fly
response to organic substanceGO:00100332840.031
organic substance catabolic processGO:19015753080.031
post embryonic appendage morphogenesisGO:00351203850.030
appendage developmentGO:00487364010.030
carboxylic acid metabolic processGO:0019752920.030
negative regulation of gene expressionGO:00106293870.030
endocytosisGO:00068973100.030
appendage morphogenesisGO:00351073970.029
forebrain developmentGO:003090020.029
imaginal disc derived appendage morphogenesisGO:00351143950.029
cellular catabolic processGO:00442483720.028
positive regulation of cellular biosynthetic processGO:00313283160.028
positive regulation of macromolecule metabolic processGO:00106044050.028
body morphogenesisGO:001017120.028
positive regulation of biosynthetic processGO:00098913160.028
response to oxygen containing compoundGO:19017002000.028
single organism behaviorGO:00447083910.026
immune responseGO:00069552460.026
cellular protein modification processGO:00064644380.026
Fly
cell deathGO:00082192790.026
programmed cell deathGO:00125012570.026
gland developmentGO:00487321910.026
vesicle mediated transportGO:00161923810.026
positive regulation of signalingGO:00230562430.026
eye morphogenesisGO:00485922600.025
positive regulation of nucleobase containing compound metabolic processGO:00459353320.025
immune system processGO:00023763470.025
establishment of localization in cellGO:00516494020.025
sensory organ morphogenesisGO:00905962600.025
transcription from rna polymerase ii promoterGO:00063663680.025
regulation of multicellular organismal developmentGO:20000264140.025
morphogenesis of an epitheliumGO:00020092760.024
eye developmentGO:00016543230.024
compound eye morphogenesisGO:00017452490.024
organic acid metabolic processGO:00060821030.024
regulation of cell cycleGO:00517262910.024
positive regulation of gene expressionGO:00106282900.024
positive regulation of response to stimulusGO:00485843230.023
xenobiotic catabolic processGO:004217810.023
positive regulation of macromolecule biosynthetic processGO:00105572830.023
deathGO:00162652840.023
steroid catabolic processGO:000670610.023
organonitrogen compound metabolic processGO:19015643180.023
small molecule metabolic processGO:00442813050.023
defense responseGO:00069523000.022
axis specificationGO:00097981670.022
organic substance transportGO:00717022570.022
developmental programmed cell deathGO:00106231380.022
central nervous system developmentGO:00074172010.022
negative regulation of cellular metabolic processGO:00313243820.022
humoral immune responseGO:00069591170.022
protein localizationGO:00081042840.021
positive regulation of nucleic acid templated transcriptionGO:19035082660.021
taxisGO:00423303040.021
regulation of localizationGO:00328792750.021
proteolysisGO:00065081920.021
cellular response to chemical stimulusGO:00708871990.021
camera type eye developmentGO:004301040.021
response to organophosphorusGO:004668320.021
negative regulation of cellular biosynthetic processGO:00313272770.021
positive regulation of cell communicationGO:00106472500.021
negative regulation of nitrogen compound metabolic processGO:00511722650.020
negative regulation of signalingGO:00230572190.020
negative regulation of cell communicationGO:00106482230.020
negative regulation of biosynthetic processGO:00098902770.020
homeostatic processGO:00425921990.020
compound eye developmentGO:00487493070.020
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.020
lateral inhibitionGO:00463312060.020
tissue morphogenesisGO:00487292970.020
positive regulation of signal transductionGO:00099672230.020
ion transportGO:00068111450.020
autophagyGO:00069141080.020
tube developmentGO:00352952440.020
histolysisGO:00075591020.020
locomotory behaviorGO:00076261760.020
phagocytosisGO:00069092150.020
negative regulation of rna metabolic processGO:00512532510.019
telencephalon developmentGO:002153720.019
regulation of cellular catabolic processGO:00313291570.019
single organism catabolic processGO:00447122280.019
negative regulation of signal transductionGO:00099682060.019
phosphorylationGO:00163102940.019
vitamin metabolic processGO:000676620.019
anion homeostasisGO:005508130.019
regulation of transcription from rna polymerase ii promoterGO:00063573780.019
positive regulation of rna biosynthetic processGO:19026802660.019
multi organism behaviorGO:00517051750.019
salivary gland developmentGO:00074311620.019
pigmentationGO:0043473750.019
cell proliferationGO:00082832990.019
negative regulation of response to stimulusGO:00485852580.019
axon developmentGO:00615642970.019
kidney developmentGO:000182230.019
Human
intracellular signal transductionGO:00355563000.019
positive regulation of rna metabolic processGO:00512542710.018
neurological system processGO:00508773580.018
dorsal ventral pattern formationGO:00099531330.018
localization of cellGO:00516742570.018
regulation of response to stressGO:00801342000.018
tube morphogenesisGO:00352391910.018
macromolecule catabolic processGO:00090571610.018
regulation of intracellular signal transductionGO:19025312360.018
exocrine system developmentGO:00352721620.018
regulation of cellular ketone metabolic processGO:001056530.018
intracellular transportGO:00469072280.018
tissue deathGO:00162711020.018
amine metabolic processGO:0009308120.018
regulation of cellular protein metabolic processGO:00322682430.018
monocarboxylic acid transportGO:001571830.018
organelle fissionGO:00482853400.018
negative regulation of macromolecule biosynthetic processGO:00105582700.018
regulation of organelle organizationGO:00330431960.018
regulation of cellular amine metabolic processGO:003323830.018
negative regulation of nucleobase containing compound metabolic processGO:00459342610.017
carbohydrate derivative metabolic processGO:19011352170.017
Fly
epithelial cell differentiationGO:00308553220.017
salivary gland histolysisGO:0035070880.017
cell motilityGO:00488702510.017
hormone catabolic processGO:004244730.017
androgen metabolic processGO:000820910.017
dendrite developmentGO:00163582040.017
chromosome organizationGO:00512763600.017
establishment or maintenance of cell polarityGO:00071631670.017
salivary gland morphogenesisGO:00074351450.017
organic cyclic compound catabolic processGO:19013611680.017
macromolecular complex assemblyGO:00650032560.017
anterior posterior axis specification embryoGO:00085951030.017
gland morphogenesisGO:00226121450.017
single organism biosynthetic processGO:00447112060.017
regulation of immune system processGO:00026821760.017
anterior posterior pattern specificationGO:00099521360.017
regulation of cell differentiationGO:00455953020.017
single organism intracellular transportGO:19025822070.016
regulation of protein metabolic processGO:00512462560.016
gene silencingGO:00164581380.016
antimicrobial humoral responseGO:0019730990.016
developmental growthGO:00485892800.016
organophosphate metabolic processGO:00196371950.016
growthGO:00400073590.016
ion transmembrane transportGO:00342201220.016
regulation of catabolic processGO:00098941700.016
nuclear divisionGO:00002803320.016
protein complex biogenesisGO:00702712010.016
cellular amine metabolic processGO:0044106120.016
segmentationGO:00352822070.016
innate immune responseGO:00450871440.016
establishment of planar polarityGO:0001736870.016
defense response to other organismGO:00985422250.016
regulation of cell proliferationGO:00421271630.016
regulation of phosphate metabolic processGO:00192202100.016
negative regulation of rna biosynthetic processGO:19026792400.016
regulation of catalytic activityGO:00507901850.016
inter male aggressive behaviorGO:0002121600.016
embryonic development via the syncytial blastodermGO:00017001480.015
adult behaviorGO:00305341370.015
ovarian follicle cell developmentGO:00307072480.015
regulation of anatomical structure morphogenesisGO:00226032420.015
cellular amino acid metabolic processGO:0006520610.015
establishment of tissue polarityGO:0007164870.015
protein complex assemblyGO:00064612000.015
photoreceptor cell differentiationGO:00465301700.015
epithelial cell developmentGO:00020642740.015
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.015
positive regulation of transcription dna templatedGO:00458932660.015
maintenance of locationGO:0051235730.015
connective tissue developmentGO:006144830.015
protein transportGO:00150311550.015
chromosome segregationGO:00070591570.015
compound eye photoreceptor cell differentiationGO:00017511400.015
open tracheal system developmentGO:00074242040.015
regulation of molecular functionGO:00650092170.015
chemotaxisGO:00069352490.015
developmental maturationGO:00217001720.014
response to extracellular stimulusGO:00099911160.014
response to alcoholGO:0097305950.014
blastoderm segmentationGO:00073501590.014
morphogenesis of a polarized epitheliumGO:0001738930.014
response to woundingGO:0009611940.014
neuron projection guidanceGO:00974852410.014
spindle organizationGO:00070512530.014
aggressive behaviorGO:0002118630.014
regulation of phosphorus metabolic processGO:00511742100.014
digestive tract morphogenesisGO:00485461270.014
organonitrogen compound biosynthetic processGO:19015661170.014
cellular macromolecule localizationGO:00707272200.014
eye photoreceptor cell differentiationGO:00017541450.014
negative regulation of nucleic acid templated transcriptionGO:19035072400.014
autophagic cell deathGO:0048102830.014
negative regulation of developmental processGO:00510932010.014
single organism carbohydrate metabolic processGO:0044723720.014
Fly
embryonic pattern specificationGO:00098801740.014
actin filament based processGO:00300292200.014
benzene containing compound metabolic processGO:004253730.014
defense response to bacteriumGO:00427421780.014
response to glucoseGO:000974920.014
columnar cuboidal epithelial cell differentiationGO:00020652560.014
positive regulation of cell motilityGO:200014730.014
immune response activating signal transductionGO:000275720.014
cellular response to organic substanceGO:00713101320.014
cellular macromolecule catabolic processGO:00442651360.014
positive regulation of cell migrationGO:003033520.014
regulation of cell cycle processGO:00105641810.014
response to nutrient levelsGO:00316671140.014
mitotic spindle organizationGO:00070522200.014
neuropeptide signaling pathwayGO:0007218450.014
enzyme linked receptor protein signaling pathwayGO:00071671790.014
cell cell signaling involved in cell fate commitmentGO:00451682100.014
response to organic cyclic compoundGO:0014070890.014
fat soluble vitamin metabolic processGO:000677510.014
salivary gland cell autophagic cell deathGO:0035071830.014
columnar cuboidal epithelial cell developmentGO:00020662490.014
cell migrationGO:00164772380.013
mesenchymal cell differentiationGO:004876210.013
regulation of transportGO:00510491810.013
nucleoside phosphate metabolic processGO:00067531620.013
cellular response to ethanolGO:007136140.013
negative regulation of transcription dna templatedGO:00458922370.013
embryonic morphogenesisGO:00485982060.013
axonogenesisGO:00074092900.013
apoptotic processGO:00069151590.013
respiratory system developmentGO:00605412130.013
response to copper ionGO:004668840.013
regulation of programmed cell deathGO:00430671520.013
aromatic compound catabolic processGO:00194391660.013
protein catabolic processGO:00301631010.013
estrogen metabolic processGO:000821010.013
establishment of protein localizationGO:00451841630.013
carbohydrate derivative biosynthetic processGO:1901137850.013
Fly
regulation of cell deathGO:00109411730.013
axon guidanceGO:00074112330.013
wound healingGO:0042060750.013
negative regulation of cellular component organizationGO:00511291080.013
ras protein signal transductionGO:0007265880.013
chaeta developmentGO:0022416970.013
cellular ketone metabolic processGO:0042180240.013
tripartite regional subdivisionGO:00073511030.013
multicellular organismal agingGO:00102591400.013
embryonic axis specificationGO:00005781070.013
heterocycle catabolic processGO:00467001660.013
immune response regulating signaling pathwayGO:000276420.012
wnt signaling pathwayGO:0016055980.012
cell recognitionGO:00080371020.012
carbohydrate metabolic processGO:0005975820.012
Fly
regulation of cellular amino acid metabolic processGO:000652100.012
ethanolamine containing compound metabolic processGO:004243940.012
positive regulation of phosphorus metabolic processGO:00105621390.012
wing disc pattern formationGO:0035222660.012
nucleobase containing small molecule metabolic processGO:00550861740.012
positive regulation of phosphate metabolic processGO:00459371390.012
transmembrane transportGO:00550851390.012
spermatogenesisGO:00072832000.012
photoreceptor cell developmentGO:0042461960.012
single organism cellular localizationGO:19025801800.012
dna metabolic processGO:00062592270.012
cellular response to dna damage stimulusGO:00069742230.012
response to radiationGO:00093141550.012
protein phosphorylationGO:00064681690.012
response to endogenous stimulusGO:00097191190.012
dendrite morphogenesisGO:00488131990.012
posttranscriptional regulation of gene expressionGO:00106081450.012
response to monosaccharideGO:003428440.012
regulation of anatomical structure sizeGO:00900661630.012
head developmentGO:00603221350.012
anterior posterior axis specificationGO:00099481090.012
sterol homeostasisGO:005509240.012
cation transportGO:00068121100.012
regulation of cell developmentGO:00602842150.012
regulation of gene expression epigeneticGO:00400291280.012
regulation of cellular component biogenesisGO:00440872010.012
response to hexoseGO:000974630.012
developmental pigmentationGO:0048066680.012
nucleotide metabolic processGO:00091171610.012
cellular component assembly involved in morphogenesisGO:00109271510.012
hindbrain developmentGO:003090220.012
regulation of phosphorylationGO:00423251470.011
proteolysis involved in cellular protein catabolic processGO:0051603830.011
cell divisionGO:00513012480.011
small gtpase mediated signal transductionGO:0007264880.011
secondary metabolic processGO:0019748750.011
anatomical structure homeostasisGO:0060249970.011
vitamin biosynthetic processGO:000911010.011
cellular nitrogen compound catabolic processGO:00442701650.011
positive regulation of catabolic processGO:00098961050.011
ribonucleotide metabolic processGO:00092591450.011
glycerolipid catabolic processGO:004650330.011
activation of innate immune responseGO:000221840.011
mitotic nuclear divisionGO:00070672130.011
cuticle developmentGO:0042335860.011
pigment metabolic processGO:0042440840.011
regulation of cellular localizationGO:00603411360.011
response to nitrogen compoundGO:1901698900.011
digestive tract developmentGO:00485651490.011
cellular lipid metabolic processGO:0044255830.011
cellular response to biotic stimulusGO:007121640.011
protein processingGO:0016485680.011
male gamete generationGO:00482322010.011
mesenchymal cell developmentGO:001403110.011
inorganic ion transmembrane transportGO:0098660730.011
mitotic cell cycle phase transitionGO:00447721380.011
purine containing compound metabolic processGO:00725211550.011
signal transduction by phosphorylationGO:00230141070.011
polyol biosynthetic processGO:004617330.011
chemosensory behaviorGO:00076351060.011
positive regulation of intracellular signal transductionGO:19025331160.011
negative regulation of protein metabolic processGO:0051248850.011
muscle structure developmentGO:00610612240.011
response to temperature stimulusGO:00092661060.011
dephosphorylationGO:0016311510.011
organophosphate catabolic processGO:00464341120.011
cellular macromolecular complex assemblyGO:00346221530.011
rna processingGO:00063961470.011
regulation of immune responseGO:00507761180.011
cellular response to molecule of bacterial originGO:007121930.011
determination of adult lifespanGO:00083401370.011
synaptic transmissionGO:00072682880.011
regulation of apoptotic processGO:00429811300.011
limb developmentGO:006017310.011
purine ribonucleotide metabolic processGO:00091501450.011
digestive system developmentGO:00551231490.011
purine nucleotide metabolic processGO:00061631460.011
lipid metabolic processGO:00066291210.011
synapse organizationGO:00508081960.011
mrna metabolic processGO:00160711240.011
pigment biosynthetic processGO:0046148360.011
anion transportGO:0006820410.011
mapk cascadeGO:00001651070.011
negative regulation of cell differentiationGO:00455961430.011
acylglycerol catabolic processGO:004646430.011
rna localizationGO:00064031150.011
triglyceride biosynthetic processGO:001943220.011
cellular homeostasisGO:0019725800.010
notch signaling pathwayGO:00072191200.010
cellular amide metabolic processGO:0043603800.010
dorsal ventral axis specificationGO:0009950660.010
cellularizationGO:0007349900.010
leg disc developmentGO:0035218920.010
eggshell formationGO:00307031050.010
eye photoreceptor cell developmentGO:0042462810.010
neuron recognitionGO:00080381010.010
positive regulation of cellular catabolic processGO:0031331950.010
nitrogen compound transportGO:0071705850.010
regulation of synapse structure and activityGO:00508031280.010
retina development in camera type eyeGO:006004140.010
acylglycerol biosynthetic processGO:004646320.010
regulation of cell shapeGO:00083601130.010
regulation of hydrolase activityGO:0051336970.010
cholesterol homeostasisGO:004263230.010
ameboidal type cell migrationGO:00016671510.010
regulation of lipid transportGO:003236830.010
response to oxidative stressGO:0006979860.010
somatic muscle developmentGO:0007525660.010

tgy disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.042
disease of metabolismDOID:001466700.025
inherited metabolic disorderDOID:65500.020
nervous system diseaseDOID:86300.019
cardiovascular system diseaseDOID:128700.017
acquired metabolic diseaseDOID:006015800.015
artery diseaseDOID:005082800.013
vascular diseaseDOID:17800.013
hypertensionDOID:1076300.013
glucose metabolism diseaseDOID:419400.011
diabetes mellitusDOID:935100.011
type 2 diabetes mellitusDOID:935200.011
carbohydrate metabolism diseaseDOID:005001300.011
essential hypertensionDOID:1082500.011
sensory system diseaseDOID:005015500.010