Drosophila melanogaster

115 known processes

Jafrac2 (Dmel_CG1274)

thioredoxin peroxidase 2

(Aliases: Dmel\CG1274,CG1274,1274,Jafrac-2,Prx4156,DPx4156,DPx-4156)

Jafrac2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
programmed cell deathGO:00125012570.183
oxidation reduction processGO:00551141230.139
positive regulation of response to stimulusGO:00485843230.135
developmental programmed cell deathGO:00106231380.100
regulation of catalytic activityGO:00507901850.096
response to alcoholGO:0097305950.091
intracellular signal transductionGO:00355563000.088
autophagyGO:00069141080.084
response to organic substanceGO:00100332840.077
response to oxygen radicalGO:000030530.076
positive regulation of signalingGO:00230562430.075
regulation of cell deathGO:00109411730.071
negative regulation of cellular metabolic processGO:00313243820.070
appendage developmentGO:00487364010.066
deathGO:00162652840.065
immune system processGO:00023763470.062
dendrite morphogenesisGO:00488131990.061
regulation of molecular functionGO:00650092170.061
regulation of immune system processGO:00026821760.060
regulation of multicellular organismal developmentGO:20000264140.059
regulation of hydrolase activityGO:0051336970.058
amine metabolic processGO:0009308120.056
regulation of response to stressGO:00801342000.056
cell deathGO:00082192790.050
response to biotic stimulusGO:00096072940.050
response to oxygen containing compoundGO:19017002000.048
regulation of localizationGO:00328792750.048
gland developmentGO:00487321910.047
positive regulation of molecular functionGO:00440931360.047
regulation of anatomical structure morphogenesisGO:00226032420.046
purine containing compound metabolic processGO:00725211550.045
secretion by cellGO:00329401010.045
positive regulation of proteolysisGO:0045862520.044
salivary gland cell autophagic cell deathGO:0035071830.044
response to other organismGO:00517072930.043
salivary gland morphogenesisGO:00074351450.042
locomotory behaviorGO:00076261760.041
growthGO:00400073590.041
dendrite developmentGO:00163582040.041
regulation of transportGO:00510491810.041
tissue deathGO:00162711020.040
autophagic cell deathGO:0048102830.040
positive regulation of catalytic activityGO:00430851180.040
positive regulation of signal transductionGO:00099672230.038
response to radiationGO:00093141550.038
apoptotic processGO:00069151590.038
positive regulation of programmed cell deathGO:0043068620.037
negative regulation of molecular functionGO:0044092510.036
intrinsic apoptotic signaling pathwayGO:0097193160.036
positive regulation of cell communicationGO:00106472500.036
positive regulation of macromolecule metabolic processGO:00106044050.035
defense responseGO:00069523000.035
cation transportGO:00068121100.034
cellular response to extracellular stimulusGO:0031668640.034
Yeast
regulation of growthGO:00400082330.034
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.034
protein modification processGO:00362114380.032
positive regulation of apoptotic signaling pathwayGO:200123540.032
protein complex assemblyGO:00064612000.032
exocrine system developmentGO:00352721620.031
regulation of catabolic processGO:00098941700.030
salivary gland developmentGO:00074311620.030
cellular response to organic substanceGO:00713101320.029
regulation of endopeptidase activityGO:0052548360.029
regulation of peptidase activityGO:0052547390.029
salivary gland histolysisGO:0035070880.029
regulation of programmed cell deathGO:00430671520.029
carbohydrate derivative metabolic processGO:19011352170.029
response to external biotic stimulusGO:00432072930.028
sex differentiationGO:0007548810.028
response to ethanolGO:0045471590.027
cellular protein modification processGO:00064644380.027
negative regulation of programmed cell deathGO:0043069720.027
Fly
intracellular protein transportGO:00068861040.026
cellular homeostasisGO:0019725800.026
Yeast Fly
regulation of cellular catabolic processGO:00313291570.026
regulation of anatomical structure sizeGO:00900661630.026
regulation of multi organism processGO:00439001310.026
regulation of intracellular signal transductionGO:19025312360.026
muscle organ developmentGO:00075171270.026
regulation of apoptotic processGO:00429811300.026
cellular catabolic processGO:00442483720.026
single organism cellular localizationGO:19025801800.026
regulation of cell differentiationGO:00455953020.025
energy derivation by oxidation of organic compoundsGO:0015980320.025
gland morphogenesisGO:00226121450.025
homeostatic processGO:00425921990.025
Yeast Fly
regulation of autophagyGO:0010506620.025
regulation of i kappab kinase nf kappab signalingGO:004312220.025
intracellular transportGO:00469072280.025
transcription from rna polymerase ii promoterGO:00063663680.025
organonitrogen compound metabolic processGO:19015643180.025
histolysisGO:00075591020.025
establishment of protein localizationGO:00451841630.024
cytoplasmic transportGO:00164821300.024
imaginal disc derived appendage morphogenesisGO:00351143950.024
organic substance transportGO:00717022570.024
imaginal disc derived wing morphogenesisGO:00074763370.024
divalent inorganic cation homeostasisGO:0072507290.023
protein transportGO:00150311550.023
secretionGO:00469031090.023
regulation of protein localizationGO:0032880760.023
purine ribonucleoside metabolic processGO:00461281270.023
adult behaviorGO:00305341370.023
positive regulation of multicellular organismal processGO:00512401430.023
cellular amine metabolic processGO:0044106120.023
multicellular organismal agingGO:00102591400.023
Fly
response to abiotic stimulusGO:00096283410.022
macromolecular complex assemblyGO:00650032560.022
cellular response to oxidative stressGO:0034599280.022
positive regulation of cellular biosynthetic processGO:00313283160.022
synaptic transmissionGO:00072682880.022
transmembrane transportGO:00550851390.022
appendage morphogenesisGO:00351073970.022
imaginal disc derived appendage developmentGO:00487373990.021
regulation of cellular localizationGO:00603411360.021
dna damage checkpointGO:0000077780.021
Yeast
regulation of protein transportGO:0051223570.021
immune effector processGO:0002252980.021
establishment of localization in cellGO:00516494020.021
regulation of protein metabolic processGO:00512462560.021
taxisGO:00423303040.020
positive regulation of cellular component organizationGO:00511301560.020
telencephalon developmentGO:002153720.020
immune responseGO:00069552460.020
developmental growthGO:00485892800.020
response to superoxideGO:000030330.019
positive regulation of cysteine type endopeptidase activityGO:2001056240.019
positive regulation of nitrogen compound metabolic processGO:00511733540.019
positive regulation of gene expressionGO:00106282900.019
negative regulation of cell communicationGO:00106482230.019
negative regulation of response to stimulusGO:00485852580.018
positive regulation of biosynthetic processGO:00098913160.018
response to oxidative stressGO:0006979860.018
positive regulation of hydrolase activityGO:0051345780.018
cellular response to chemical stimulusGO:00708871990.018
sensory organ morphogenesisGO:00905962600.018
determination of adult lifespanGO:00083401370.018
Fly
negative regulation of nitrogen compound metabolic processGO:00511722650.018
positive regulation of cell deathGO:0010942690.017
signal transduction by phosphorylationGO:00230141070.017
regulation of proteolysisGO:0030162870.017
positive regulation of nucleobase containing compound metabolic processGO:00459353320.017
ribonucleotide catabolic processGO:00092611090.017
nuclear divisionGO:00002803320.017
carbohydrate metabolic processGO:0005975820.017
negative regulation of catalytic activityGO:0043086420.017
brain developmentGO:00074201200.016
positive regulation of rna biosynthetic processGO:19026802660.016
forebrain developmentGO:003090020.016
positive regulation of apoptotic processGO:0043065470.016
carbohydrate derivative catabolic processGO:19011361180.016
single organism carbohydrate metabolic processGO:0044723720.016
regulation of transcription from rna polymerase ii promoterGO:00063573780.016
negative regulation of rna metabolic processGO:00512532510.016
single organism membrane organizationGO:0044802930.016
nucleoside phosphate metabolic processGO:00067531620.015
cell divisionGO:00513012480.015
membrane organizationGO:00610241120.015
humoral immune responseGO:00069591170.015
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stressGO:007005940.015
regulation of cellular response to oxidative stressGO:190040740.015
immune system developmentGO:0002520570.015
negative regulation of cell deathGO:0060548810.015
Fly
mushroom body developmentGO:0016319700.015
immune response activating signal transductionGO:000275720.015
phenol containing compound metabolic processGO:0018958570.015
positive regulation of transcription dna templatedGO:00458932660.015
protein processingGO:0016485680.015
cellular response to external stimulusGO:0071496660.015
Yeast
nucleobase containing small molecule metabolic processGO:00550861740.014
positive regulation of i kappab kinase nf kappab signalingGO:004312310.014
vesicle mediated transportGO:00161923810.014
Fly
neurological system processGO:00508773580.014
macromolecule catabolic processGO:00090571610.014
regulation of innate immune responseGO:0045088710.014
catabolic processGO:00090564090.014
protein localizationGO:00081042840.014
ribonucleoside catabolic processGO:00424541120.014
positive regulation of cell motilityGO:200014730.014
organonitrogen compound biosynthetic processGO:19015661170.014
regulation of cytoplasmic transportGO:1903649470.014
protein maturationGO:0051604710.014
negative regulation of signalingGO:00230572190.014
nucleotide metabolic processGO:00091171610.014
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280230.014
immune response regulating signaling pathwayGO:000276420.014
positive regulation of protein metabolic processGO:00512471280.014
cellular amide metabolic processGO:0043603800.014
single organism intracellular transportGO:19025822070.014
positive regulation of developmental processGO:00510941430.014
regulation of organelle organizationGO:00330431960.014
cellular biogenic amine catabolic processGO:004240210.013
defense response to bacteriumGO:00427421780.013
single organism biosynthetic processGO:00447112060.013
regulation of immune responseGO:00507761180.013
actin filament organizationGO:00070151260.013
positive regulation of transportGO:0051050920.013
wing disc morphogenesisGO:00074723440.013
regulation of developmental growthGO:00486381740.013
single organism behaviorGO:00447083910.013
positive regulation of cellular catabolic processGO:0031331950.013
ion transportGO:00068111450.012
peptidyl amino acid modificationGO:00181931050.012
wnt signaling pathwayGO:0016055980.012
embryonic development via the syncytial blastodermGO:00017001480.012
phagocytosisGO:00069092150.012
Fly
positive regulation of macromolecule biosynthetic processGO:00105572830.012
cellular response to starvationGO:0009267610.012
regulation of wnt signaling pathwayGO:0030111680.012
multi multicellular organism processGO:00447061230.012
small molecule metabolic processGO:00442813050.012
regulation of defense responseGO:00313471020.012
regulation of cellular amine metabolic processGO:003323830.012
atp metabolic processGO:0046034490.012
positive regulation of endopeptidase activityGO:0010950260.012
protein catabolic processGO:00301631010.012
cellular lipid metabolic processGO:0044255830.012
response to lipopolysaccharideGO:003249640.012
negative regulation of multicellular organismal processGO:00512411420.012
response to endogenous stimulusGO:00097191190.012
regulation of phosphorus metabolic processGO:00511742100.012
purine nucleoside metabolic processGO:00422781270.011
ribonucleoside triphosphate metabolic processGO:00091991190.011
metal ion transportGO:0030001740.011
anatomical structure homeostasisGO:0060249970.011
mrna processingGO:00063971040.011
protein targetingGO:0006605640.011
cellular macromolecule localizationGO:00707272200.011
cellular response to nutrient levelsGO:0031669620.011
proteolysisGO:00065081920.011
response to bacteriumGO:00096171980.011
purine ribonucleotide metabolic processGO:00091501450.011
mitotic nuclear divisionGO:00070672130.011
extrinsic apoptotic signaling pathwayGO:009719110.011
regulation of phosphate metabolic processGO:00192202100.011
regulation of cellular ketone metabolic processGO:001056530.011
regulation of cell cycle processGO:00105641810.011
negative regulation of cellular catabolic processGO:0031330340.010
negative regulation of cell differentiationGO:00455961430.010
cell agingGO:000756920.010
Yeast
protein importGO:0017038550.010
eye morphogenesisGO:00485922600.010

Jafrac2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.044
disease of cellular proliferationDOID:1456600.023
cancerDOID:16200.023
organ system cancerDOID:005068600.018
nervous system diseaseDOID:86300.015
central nervous system diseaseDOID:33100.015
neurodegenerative diseaseDOID:128900.013