Drosophila melanogaster

93 known processes

Pk92B (Dmel_CG4720)

Protein kinase at 92B

(Aliases: Ask1,Dmel\CG4720,DPk92B/ASK1,CG4720,DASK1,DASK,MEKK5/ASK1,ASK1,dASK)

Pk92B biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of intracellular signal transductionGO:19025312360.316
immune responseGO:00069552460.233
organonitrogen compound catabolic processGO:19015651280.199
post embryonic appendage morphogenesisGO:00351203850.192
glycosyl compound catabolic processGO:19016581120.182
imaginal disc derived appendage morphogenesisGO:00351143950.168
regulation of response to stressGO:00801342000.166
homeostatic processGO:00425921990.160
catabolic processGO:00090564090.147
purine ribonucleoside metabolic processGO:00461281270.141
establishment of localization in cellGO:00516494020.133
imaginal disc derived wing morphogenesisGO:00074763370.132
appendage morphogenesisGO:00351073970.129
cell proliferationGO:00082832990.124
defense response to other organismGO:00985422250.124
cellular nitrogen compound catabolic processGO:00442701650.123
ribonucleoside triphosphate catabolic processGO:00092031080.120
positive regulation of response to stimulusGO:00485843230.116
heterocycle catabolic processGO:00467001660.116
negative regulation of signal transductionGO:00099682060.115
positive regulation of signalingGO:00230562430.115
positive regulation of immune responseGO:0050778630.114
ribonucleotide catabolic processGO:00092611090.114
nucleotide catabolic processGO:00091661090.113
organophosphate metabolic processGO:00196371950.113
purine nucleoside catabolic processGO:00061521120.108
tube morphogenesisGO:00352391910.104
organic substance catabolic processGO:19015753080.104
regulation of mapk cascadeGO:0043408920.104
defense responseGO:00069523000.104
purine ribonucleoside triphosphate catabolic processGO:00092071080.103
immune response regulating signaling pathwayGO:000276420.102
positive regulation of nucleobase containing compound metabolic processGO:00459353320.102
single organism behaviorGO:00447083910.101
stress activated mapk cascadeGO:0051403520.101
macromolecular complex assemblyGO:00650032560.100
purine nucleoside triphosphate metabolic processGO:00091441190.098
nucleoside triphosphate metabolic processGO:00091411200.096
small molecule metabolic processGO:00442813050.095
positive regulation of biosynthetic processGO:00098913160.091
imaginal disc derived appendage developmentGO:00487373990.090
ribose phosphate metabolic processGO:00196931450.090
cell divisionGO:00513012480.089
morphogenesis of an epitheliumGO:00020092760.088
cellular response to chemical stimulusGO:00708871990.087
Human Mouse
organonitrogen compound metabolic processGO:19015643180.087
regulation of cellular response to stressGO:0080135890.084
wing disc morphogenesisGO:00074723440.084
glycosyl compound metabolic processGO:19016571270.084
nucleobase containing compound catabolic processGO:00346551650.084
carbohydrate derivative metabolic processGO:19011352170.083
phosphorylationGO:00163102940.082
response to abiotic stimulusGO:00096283410.082
ribonucleoside triphosphate metabolic processGO:00091991190.081
regulation of purine nucleotide metabolic processGO:1900542620.080
organic cyclic compound catabolic processGO:19013611680.079
purine ribonucleotide metabolic processGO:00091501450.079
response to organic substanceGO:00100332840.079
positive regulation of macromolecule biosynthetic processGO:00105572830.077
purine containing compound metabolic processGO:00725211550.076
ribonucleotide metabolic processGO:00092591450.075
gtp metabolic processGO:0046039720.075
cell maturationGO:00484691440.074
negative regulation of gene expressionGO:00106293870.072
positive regulation of signal transductionGO:00099672230.072
stem cell differentiationGO:00488631170.071
nucleoside phosphate catabolic processGO:19012921100.070
carbohydrate derivative catabolic processGO:19011361180.070
intracellular signal transductionGO:00355563000.070
transcription from rna polymerase ii promoterGO:00063663680.070
organic substance transportGO:00717022570.070
nucleobase containing small molecule metabolic processGO:00550861740.070
positive regulation of gene expressionGO:00106282900.069
ras protein signal transductionGO:0007265880.069
regulation of localizationGO:00328792750.068
immune system processGO:00023763470.067
purine ribonucleoside triphosphate metabolic processGO:00092051190.067
ribonucleoside metabolic processGO:00091191270.066
regulation of phosphorus metabolic processGO:00511742100.066
appendage developmentGO:00487364010.066
mapk cascadeGO:00001651070.065
nucleoside metabolic processGO:00091161270.065
developmental maturationGO:00217001720.063
response to endogenous stimulusGO:00097191190.063
regulation of epithelial cell proliferationGO:005067840.062
positive regulation of cell communicationGO:00106472500.062
tissue morphogenesisGO:00487292970.062
regulation of multi organism processGO:00439001310.062
regulation of phosphate metabolic processGO:00192202100.061
positive regulation of nucleic acid templated transcriptionGO:19035082660.061
central nervous system developmentGO:00074172010.060
regulation of molecular functionGO:00650092170.060
Human Mouse
transmembrane transportGO:00550851390.059
purine ribonucleotide catabolic processGO:00091541090.059
nucleotide metabolic processGO:00091171610.059
positive regulation of cellular biosynthetic processGO:00313283160.058
stress activated protein kinase signaling cascadeGO:0031098550.058
regulation of phosphorylationGO:00423251470.057
compound eye developmentGO:00487493070.057
negative regulation of cell communicationGO:00106482230.057
molting cycleGO:0042303560.057
nucleoside triphosphate catabolic processGO:00091431080.057
regulation of nucleotide metabolic processGO:0006140620.057
purine nucleotide metabolic processGO:00061631460.056
regulation of nucleoside metabolic processGO:0009118500.056
stem cell maintenanceGO:0019827670.056
negative regulation of signalingGO:00230572190.056
positive regulation of catalytic activityGO:00430851180.054
Human Mouse
dna metabolic processGO:00062592270.053
negative regulation of response to stimulusGO:00485852580.053
gtp catabolic processGO:0006184720.052
response to other organismGO:00517072930.052
oocyte developmentGO:00485991240.051
nucleoside catabolic processGO:00091641120.051
hindgut morphogenesisGO:0007442580.050
negative regulation of developmental processGO:00510932010.049
gland morphogenesisGO:00226121450.047
positive regulation of rna metabolic processGO:00512542710.047
hindgut developmentGO:0061525580.046
purine ribonucleoside catabolic processGO:00461301120.046
signal transduction by phosphorylationGO:00230141070.046
biological adhesionGO:00226101380.046
neuron projection guidanceGO:00974852410.046
purine nucleoside triphosphate catabolic processGO:00091461080.046
agingGO:00075681430.045
regulation of immune system processGO:00026821760.045
positive regulation of phosphate metabolic processGO:00459371390.045
aromatic compound catabolic processGO:00194391660.045
axonogenesisGO:00074092900.045
regulation of developmental pigmentationGO:0048070240.044
dendrite developmentGO:00163582040.044
purine nucleotide catabolic processGO:00061951090.044
organophosphate catabolic processGO:00464341120.041
dendrite morphogenesisGO:00488131990.041
developmental programmed cell deathGO:00106231380.041
regulation of catalytic activityGO:00507901850.041
Human Mouse
nucleoside phosphate metabolic processGO:00067531620.040
regulation of immune responseGO:00507761180.040
small gtpase mediated signal transductionGO:0007264880.040
purine containing compound catabolic processGO:00725231120.040
molting cycle chitin based cuticleGO:0007591560.039
cellular protein complex assemblyGO:0043623710.039
anterior posterior pattern specificationGO:00099521360.039
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.038
cellular catabolic processGO:00442483720.038
cellular macromolecule localizationGO:00707272200.038
mitotic nuclear divisionGO:00070672130.037
regionalizationGO:00030024160.037
chemotaxisGO:00069352490.035
response to gravityGO:0009629260.035
cellular response to growth factor stimulusGO:0071363300.035
positive regulation of phosphorus metabolic processGO:00105621390.035
hindbrain developmentGO:003090220.035
guanosine containing compound metabolic processGO:1901068740.035
regulation of innate immune responseGO:0045088710.034
negative regulation of biosynthetic processGO:00098902770.034
response to bacteriumGO:00096171980.034
germarium derived egg chamber formationGO:00072931010.033
organelle fissionGO:00482853400.033
regulation of stress activated mapk cascadeGO:0032872410.033
single organism catabolic processGO:00447122280.032
ribonucleoside catabolic processGO:00424541120.032
cation transportGO:00068121100.032
positive regulation of mapk cascadeGO:0043410630.031
single organism intracellular transportGO:19025822070.031
macromolecule catabolic processGO:00090571610.031
regulation of apoptotic processGO:00429811300.031
Human Mouse
establishment of protein localizationGO:00451841630.031
gene silencingGO:00164581380.030
positive regulation of hydrolase activityGO:0051345780.030
Human
response to oxygen containing compoundGO:19017002000.030
Human
regulation of nucleotide catabolic processGO:0030811480.030
positive regulation of nitrogen compound metabolic processGO:00511733540.030
regulation of anatomical structure morphogenesisGO:00226032420.030
cell migrationGO:00164772380.030
positive regulation of transcription dna templatedGO:00458932660.029
phagocytosisGO:00069092150.029
positive regulation of histone deacetylationGO:003106520.029
adherens junction organizationGO:0034332270.029
positive regulation of molecular functionGO:00440931360.029
Human Mouse
spinal cord developmentGO:002151010.029
stem cell proliferationGO:0072089880.029
gland developmentGO:00487321910.028
purine nucleoside metabolic processGO:00422781270.028
stem cell divisionGO:0017145690.028
renal system developmentGO:0072001720.028
immune response activating signal transductionGO:000275720.028
protein localizationGO:00081042840.028
regulation of cellular catabolic processGO:00313291570.028
intracellular transportGO:00469072280.027
regulation of gtp catabolic processGO:0033124440.027
defense response to gram negative bacteriumGO:0050829940.027
positive regulation of purine nucleotide metabolic processGO:1900544550.027
negative regulation of cell differentiationGO:00455961430.027
pigmentationGO:0043473750.027
cellular response to endogenous stimulusGO:0071495800.027
regulation of cell shapeGO:00083601130.026
negative regulation of cellular metabolic processGO:00313243820.026
actin cytoskeleton organizationGO:00300362060.026
regulation of programmed cell deathGO:00430671520.026
Human Mouse
gastrulation with mouth forming firstGO:0001703360.026
humoral immune responseGO:00069591170.025
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.025
jnk cascadeGO:0007254500.025
regulation of ras gtpase activityGO:0032318380.025
exocrine system developmentGO:00352721620.025
response to growth factorGO:0070848310.024
cellular response to oxygen containing compoundGO:1901701790.024
Human
regulation of jnk cascadeGO:0046328400.024
memoryGO:0007613940.024
negative regulation of protein metabolic processGO:0051248850.024
regulation of cell deathGO:00109411730.024
Human Mouse
growthGO:00400073590.024
regulation of ras protein signal transductionGO:0046578930.024
actin filament organizationGO:00070151260.024
response to oxidative stressGO:0006979860.024
Human Mouse
positive regulation of cell differentiationGO:0045597640.024
actin filament based processGO:00300292200.024
spermatogenesisGO:00072832000.023
regulation of cell proliferationGO:00421271630.023
neurological system processGO:00508773580.023
programmed cell deathGO:00125012570.023
Human Mouse
positive regulation of developmental processGO:00510941430.023
positive regulation of phosphorylationGO:0042327870.023
protein complex assemblyGO:00064612000.023
positive regulation of cell motilityGO:200014730.023
leg disc developmentGO:0035218920.023
positive regulation of rna biosynthetic processGO:19026802660.023
anatomical structure homeostasisGO:0060249970.023
salivary gland morphogenesisGO:00074351450.022
positive regulation of defense responseGO:0031349590.022
deathGO:00162652840.022
Human Mouse
response to external biotic stimulusGO:00432072930.022
regulation of cell differentiationGO:00455953020.022
ameboidal type cell migrationGO:00016671510.022
regulation of cellular localizationGO:00603411360.022
regulation of cell cycleGO:00517262910.022
negative regulation of nucleobase containing compound metabolic processGO:00459342610.022
protein transportGO:00150311550.022
proteolysisGO:00065081920.022
Human
germ line stem cell maintenanceGO:0030718500.021
gonad developmentGO:0008406500.021
enzyme linked receptor protein signaling pathwayGO:00071671790.021
negative regulation of epithelial cell proliferationGO:005068040.021
regulation of purine nucleotide catabolic processGO:0033121480.021
locomotory behaviorGO:00076261760.021
stem cell developmentGO:0048864790.021
intracellular protein transportGO:00068861040.021
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.021
rho protein signal transductionGO:0007266140.021
olfactory behaviorGO:0042048970.021
sensory organ morphogenesisGO:00905962600.021
oocyte differentiationGO:00099941450.021
adult behaviorGO:00305341370.020
segmentationGO:00352822070.020
oocyte constructionGO:00073081120.020
innate immune responseGO:00450871440.020
neural precursor cell proliferationGO:0061351750.020
cell cell junction organizationGO:0045216550.020
embryonic organ developmentGO:0048568500.020
establishment or maintenance of cell polarityGO:00071631670.020
regulation of defense responseGO:00313471020.020
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010090.020
negative regulation of macromolecule biosynthetic processGO:00105582700.020
single organism membrane organizationGO:0044802930.019
response to heatGO:0009408630.019
regulation of cell cycle processGO:00105641810.019
response to nitrogen compoundGO:1901698900.019
Mouse
positive regulation of cell deathGO:0010942690.019
Human Mouse
positive regulation of gtpase activityGO:0043547430.019
positive regulation of cellular catabolic processGO:0031331950.019
vesicle mediated transportGO:00161923810.019
negative regulation of immune system processGO:0002683500.019
muscle organ developmentGO:00075171270.018
regulation of stress activated protein kinase signaling cascadeGO:0070302420.018
protein modification by small protein conjugation or removalGO:00706471060.018
response to extracellular stimulusGO:00099911160.018
positive regulation of nucleotide metabolic processGO:0045981550.018
male gamete generationGO:00482322010.018
regulation of adult chitin containing cuticle pigmentationGO:0048082130.018
apoptotic processGO:00069151590.018
Human Mouse
regulation of multicellular organismal developmentGO:20000264140.018
body morphogenesisGO:001017120.018
positive regulation of immune system processGO:0002684680.018
cellular protein modification processGO:00064644380.018
Human Mouse
positive regulation of nucleoside metabolic processGO:0045979470.018
defense response to bacteriumGO:00427421780.018
salivary gland developmentGO:00074311620.018
negative regulation of rna metabolic processGO:00512532510.018
oocyte axis specificationGO:00073091080.018
negative regulation of cellular protein metabolic processGO:0032269850.018
digestive tract morphogenesisGO:00485461270.017
regulation of dna metabolic processGO:0051052340.017
positive regulation of nucleotide catabolic processGO:0030813460.017
embryonic hindgut morphogenesisGO:0048619480.017
regulation of gtpase activityGO:0043087440.017
negative regulation of transcription dna templatedGO:00458922370.017
adult chitin containing cuticle pigmentationGO:0048085160.017
compound eye morphogenesisGO:00017452490.017
cell deathGO:00082192790.017
Human Mouse
cell fate determinationGO:0001709910.017
axon guidanceGO:00074112330.017
cell cell signaling involved in cell fate commitmentGO:00451682100.017
positive regulation of intracellular signal transductionGO:19025331160.017
cellular response to lipopolysaccharideGO:007122230.017
wnt signaling pathwayGO:0016055980.016
endocytosisGO:00068973100.016
protein modification processGO:00362114380.016
Human Mouse
establishment or maintenance of cytoskeleton polarityGO:0030952440.016
cytoplasmic transportGO:00164821300.016
cuticle pigmentationGO:0048067220.016
eye developmentGO:00016543230.016
negative regulation of dna dependent dna replicationGO:200010420.016
urogenital system developmentGO:0001655720.015
cellular response to organic substanceGO:00713101320.015
regulation of protein deacetylationGO:009031120.015
cellular protein localizationGO:00346131600.015
response to hormoneGO:0009725450.015
hematopoietic progenitor cell differentiationGO:000224410.015
regulation of protein localizationGO:0032880760.015
spindle organizationGO:00070512530.015
positive regulation of ras gtpase activityGO:0032320360.015
antimicrobial humoral responseGO:0019730990.015
muscle structure developmentGO:00610612240.015
regulation of cellular protein metabolic processGO:00322682430.015
Human Mouse
ovarian follicle cell developmentGO:00307072480.015
malpighian tubule developmentGO:0072002640.014
localization of cellGO:00516742570.014
lipid metabolic processGO:00066291210.014
embryonic pattern specificationGO:00098801740.014
axon developmentGO:00615642970.014
epithelial cell migration open tracheal systemGO:0007427320.014
ion transportGO:00068111450.014
activation of innate immune responseGO:000221840.014
regulation of gene expression epigeneticGO:00400291280.014
nitrogen compound transportGO:0071705850.014
mrna processingGO:00063971040.014
regulation of notch signaling pathwayGO:00085931000.014
response to biotic stimulusGO:00096072940.014
leg disc morphogenesisGO:0007478800.014
gene silencing by rnaGO:0031047570.014
forebrain developmentGO:003090020.014
ribonucleoside monophosphate metabolic processGO:0009161510.014
protein processingGO:0016485680.014
Human
imaginal disc derived wing vein morphogenesisGO:0008586440.014
cellular macromolecular complex assemblyGO:00346221530.014
secretion by cellGO:00329401010.014
positive regulation of cellular protein metabolic processGO:00322701180.014
Human Mouse
positive regulation of multicellular organismal processGO:00512401430.014
epithelial cell differentiationGO:00308553220.014
positive regulation of cell migrationGO:003033520.014
epithelial cell developmentGO:00020642740.013
negative regulation of nitrogen compound metabolic processGO:00511722650.013
dorsal closureGO:0007391790.013
morphogenesis of a branching structureGO:0001763450.013
lipopolysaccharide mediated signaling pathwayGO:003166310.013
cellular homeostasisGO:0019725800.013
embryonic development via the syncytial blastodermGO:00017001480.013
head developmentGO:00603221350.013
epidermis developmentGO:0008544650.013
tripartite regional subdivisionGO:00073511030.013
response to lipopolysaccharideGO:003249640.013
camera type eye developmentGO:004301040.013
negative regulation of intracellular signal transductionGO:1902532570.013
organelle assemblyGO:00709251980.013
molting cycle processGO:0022404290.013
cell adhesionGO:00071551360.013
peptide metabolic processGO:0006518800.012
regulation of mitotic cell cycleGO:00073461900.012
cellular response to biotic stimulusGO:007121640.012
negative regulation of programmed cell deathGO:0043069720.012
cellular response to molecule of bacterial originGO:007121930.012
renal tubule morphogenesisGO:0061333440.012
negative regulation of cellular biosynthetic processGO:00313272770.012
connective tissue developmentGO:006144830.012
regulation of phosphatase activityGO:001092130.012
membrane organizationGO:00610241120.012
determination of adult lifespanGO:00083401370.012
positive regulation of programmed cell deathGO:0043068620.012
Human Mouse
regulation of establishment of protein localizationGO:0070201610.012
developmental pigmentationGO:0048066680.012
protein catabolic processGO:00301631010.012
columnar cuboidal epithelial cell differentiationGO:00020652560.012
tissue deathGO:00162711020.012
response to organic cyclic compoundGO:0014070890.012
cellular component assembly involved in morphogenesisGO:00109271510.012
protein phosphorylationGO:00064681690.011
Human Mouse
autophagic cell deathGO:0048102830.011
eye morphogenesisGO:00485922600.011
nucleoside monophosphate metabolic processGO:0009123520.011
nuclear divisionGO:00002803320.011
taxisGO:00423303040.011
transforming growth factor beta receptor signaling pathwayGO:0007179160.011
regulation of histone deacetylationGO:003106320.011
negative regulation of multicellular organismal processGO:00512411420.011
regulation of hydrolase activityGO:0051336970.011
Human
positive regulation of catabolic processGO:00098961050.011
positive regulation of jun kinase activityGO:004350740.011
carboxylic acid metabolic processGO:0019752920.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.011
negative regulation of cell proliferationGO:0008285690.011
response to woundingGO:0009611940.011
regulation of cell morphogenesisGO:00226041630.011
positive regulation of stress activated mapk cascadeGO:0032874170.011
protein secretionGO:0009306450.011
cellular response to lipidGO:0071396200.010
regulation of transportGO:00510491810.010
regulation of catabolic processGO:00098941700.010
single organism cellular localizationGO:19025801800.010
cellular amide metabolic processGO:0043603800.010
negative regulation of cell deathGO:0060548810.010
positive regulation of purine nucleotide catabolic processGO:0033123460.010
negative regulation of dna endoreduplicationGO:003287620.010
secretionGO:00469031090.010
catechol containing compound biosynthetic processGO:000971330.010
regulation of cell divisionGO:0051302720.010

Pk92B disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.021
nervous system diseaseDOID:86300.020
disease of metabolismDOID:001466700.015
disease of cellular proliferationDOID:1456600.011