Drosophila melanogaster

78 known processes

trol (Dmel_CG33950)

terribly reduced optic lobes

(Aliases: ZW-1,l(1)G0374,l(1)zw1,l(1)G0271,l(1)trol,troll,Pcan,CG33950,Dmel\CG33950,zw1,pcan,zw-1,CT23996,EG:BACR25B3.2,EG:BACR25B3.1,GC7891,l(1)zwl,l(1)9-96,l(1)VA51,CG7981,EG:BACR25B3.11,EG:BACR25B3.10,l(1)G0023,Trol,BcDNA:GM02481,l(1)3Ac,anon-WO0153538.72,CG33675,CG12497)

trol biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
motor neuron axon guidanceGO:0008045580.884
immune system processGO:00023763470.846
growthGO:00400073590.811
positive regulation of rna metabolic processGO:00512542710.769
tube developmentGO:00352952440.767
oocyte developmentGO:00485991240.675
tube morphogenesisGO:00352391910.665
biological adhesionGO:00226101380.625
cell maturationGO:00484691440.594
establishment of localization in cellGO:00516494020.581
neuron projection guidanceGO:00974852410.579
regulation of response to stressGO:00801342000.554
membrane organizationGO:00610241120.521
positive regulation of macromolecule metabolic processGO:00106044050.460
regulation of immune system processGO:00026821760.438
developmental growthGO:00485892800.432
regulation of localizationGO:00328792750.403
response to organic substanceGO:00100332840.365
positive regulation of rna biosynthetic processGO:19026802660.361
establishment or maintenance of cell polarityGO:00071631670.360
determination of adult lifespanGO:00083401370.351
cell adhesionGO:00071551360.342
regulation of multicellular organismal developmentGO:20000264140.337
multicellular organismal agingGO:00102591400.314
response to abiotic stimulusGO:00096283410.286
immune responseGO:00069552460.261
blastoderm segmentationGO:00073501590.261
regulation of transcription from rna polymerase ii promoterGO:00063573780.250
negative regulation of response to stimulusGO:00485852580.250
mitotic cell cycle checkpointGO:0007093880.225
protein localizationGO:00081042840.212
positive regulation of nucleobase containing compound metabolic processGO:00459353320.212
cell migrationGO:00164772380.210
vesicle mediated transportGO:00161923810.204
negative regulation of cell developmentGO:0010721620.177
positive regulation of multicellular organismal processGO:00512401430.166
actin filament based processGO:00300292200.164
mitotic cell cycle phase transitionGO:00447721380.160
developmental maturationGO:00217001720.158
regulation of developmental growthGO:00486381740.150
regulation of cell projection organizationGO:0031344920.149
positive regulation of response to stimulusGO:00485843230.146
peptidyl amino acid modificationGO:00181931050.144
regulation of receptor activityGO:0010469100.143
proteolysisGO:00065081920.141
programmed cell deathGO:00125012570.140
response to anestheticGO:007234790.130
regulation of immune responseGO:00507761180.129
positive regulation of macromolecule biosynthetic processGO:00105572830.128
positive regulation of developmental growthGO:0048639620.127
positive regulation of growthGO:0045927750.126
striated muscle cell differentiationGO:0051146900.125
regulation of cell sizeGO:0008361630.125
embryo development ending in birth or egg hatchingGO:00097921520.125
negative regulation of cellular metabolic processGO:00313243820.121
purine nucleotide catabolic processGO:00061951090.121
cellular response to chemical stimulusGO:00708871990.121
positive regulation of cellular biosynthetic processGO:00313283160.119
immune response regulating signaling pathwayGO:000276420.119
cellular protein localizationGO:00346131600.118
positive regulation of transportGO:0051050920.117
extracellular structure organizationGO:0043062460.116
enzyme linked receptor protein signaling pathwayGO:00071671790.114
positive regulation of nitrogen compound metabolic processGO:00511733540.114
regulation of neuron differentiationGO:00456641030.113
gland developmentGO:00487321910.111
atp metabolic processGO:0046034490.107
regulation of innate immune responseGO:0045088710.106
regulation of cellular component sizeGO:0032535980.104
meiotic nuclear divisionGO:00071261510.103
negative regulation of signal transductionGO:00099682060.103
regulation of growthGO:00400082330.101
actin filament organizationGO:00070151260.096
cellular macromolecule localizationGO:00707272200.092
regulation of cell cycle processGO:00105641810.092
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.089
organ growthGO:0035265560.088
endocytosisGO:00068973100.088
protein modification processGO:00362114380.087
purine ribonucleoside metabolic processGO:00461281270.084
regulation of cellular ketone metabolic processGO:001056530.084
single organism catabolic processGO:00447122280.082
purine nucleoside triphosphate metabolic processGO:00091441190.081
ribonucleoside triphosphate metabolic processGO:00091991190.080
taxisGO:00423303040.079
cellular response to organic substanceGO:00713101320.079
macromolecule catabolic processGO:00090571610.078
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.077
positive regulation of mitotic sister chromatid separationGO:1901970100.077
nucleoside triphosphate metabolic processGO:00091411200.076
respiratory system developmentGO:00605412130.076
stem cell proliferationGO:0072089880.075
cell cycle phase transitionGO:00447701400.075
mitotic nuclear divisionGO:00070672130.073
protein transportGO:00150311550.072
basement membrane organizationGO:0071711100.069
meiotic cell cycle processGO:19030461320.067
regulation of neuron projection developmentGO:0010975690.066
positive regulation of cellular amine metabolic processGO:003324000.066
negative regulation of decapentaplegic signaling pathwayGO:009009940.065
axonogenesisGO:00074092900.065
body morphogenesisGO:001017120.064
epidermis developmentGO:0008544650.064
positive regulation of catabolic processGO:00098961050.060
rho protein signal transductionGO:0007266140.060
kidney developmentGO:000182230.059
development of primary sexual characteristicsGO:0045137500.059
endomembrane system organizationGO:00102561190.059
innate immune responseGO:00450871440.059
regulation of cell cycleGO:00517262910.059
larval developmentGO:00021641040.057
cellular response to dna damage stimulusGO:00069742230.057
positive regulation of nucleoside metabolic processGO:0045979470.055
axon developmentGO:00615642970.055
oxoacid metabolic processGO:00434361030.055
nucleus localizationGO:0051647340.055
reproductive system developmentGO:0061458740.053
tissue morphogenesisGO:00487292970.053
regulation of anatomical structure sizeGO:00900661630.052
embryonic pattern specificationGO:00098801740.052
cellular protein modification processGO:00064644380.051
morphogenesis of an epitheliumGO:00020092760.051
positive regulation of immune responseGO:0050778630.050
response to woundingGO:0009611940.050
regulation of glutamate receptor signaling pathwayGO:190044910.050
regulation of cell cycle phase transitionGO:19019871300.049
nucleotide metabolic processGO:00091171610.049
negative regulation of mitotic cell cycleGO:00459301090.049
apoptotic processGO:00069151590.048
anterior posterior axis specificationGO:00099481090.047
positive regulation of biosynthetic processGO:00098913160.046
response to endogenous stimulusGO:00097191190.045
cell growthGO:00160491080.045
epithelial cell differentiationGO:00308553220.045
regulation of microtubule based processGO:0032886490.045
establishment of protein localizationGO:00451841630.044
regulation of cell morphogenesisGO:00226041630.044
positive regulation of developmental processGO:00510941430.044
instar larval developmentGO:0002168550.044
single organism cellular localizationGO:19025801800.043
organic acid metabolic processGO:00060821030.043
skin developmentGO:0043588650.042
positive regulation of nucleic acid templated transcriptionGO:19035082660.042
protein catabolic processGO:00301631010.042
positive regulation of cellular amino acid metabolic processGO:004576400.041
meiosis iGO:0007127590.041
positive regulation of transcription dna templatedGO:00458932660.041
notch signaling pathwayGO:00072191200.041
immune response activating signal transductionGO:000275720.040
intracellular transportGO:00469072280.040
regulation of locomotionGO:0040012420.039
single organism membrane organizationGO:0044802930.039
cell cell signaling involved in cell fate commitmentGO:00451682100.039
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.038
chromosome segregationGO:00070591570.038
ribonucleoside metabolic processGO:00091191270.038
glycosyl compound catabolic processGO:19016581120.038
cell motilityGO:00488702510.037
muscle structure developmentGO:00610612240.037
immune effector processGO:0002252980.037
actin cytoskeleton organizationGO:00300362060.037
chemotaxisGO:00069352490.037
localization of cellGO:00516742570.036
asymmetric stem cell divisionGO:0098722490.036
positive regulation of immune system processGO:0002684680.036
amine metabolic processGO:0009308120.036
negative regulation of cell communicationGO:00106482230.035
regulation of defense responseGO:00313471020.035
regulation of catalytic activityGO:00507901850.034
immune system developmentGO:0002520570.034
positive regulation of protein metabolic processGO:00512471280.034
carboxylic acid metabolic processGO:0019752920.034
transcription from rna polymerase ii promoterGO:00063663680.033
ribonucleoside triphosphate catabolic processGO:00092031080.032
organic substance catabolic processGO:19015753080.032
sister chromatid segregationGO:0000819920.032
positive regulation of cell deathGO:0010942690.031
dorsal ventral axis specificationGO:0009950660.031
organonitrogen compound metabolic processGO:19015643180.031
cellular macromolecule catabolic processGO:00442651360.031
purine nucleoside metabolic processGO:00422781270.031
positive regulation of axonogenesisGO:005077220.030
lateral inhibitionGO:00463312060.030
brain developmentGO:00074201200.030
single organism intracellular transportGO:19025822070.030
extracellular matrix organizationGO:0030198320.029
activation of ras gtpase activityGO:003285660.029
modification dependent protein catabolic processGO:0019941780.029
positive regulation of signal transductionGO:00099672230.029
homeostatic processGO:00425921990.028
purine ribonucleoside triphosphate metabolic processGO:00092051190.028
reproductive structure developmentGO:0048608740.028
positive regulation of cellular catabolic processGO:0031331950.028
salivary gland cell autophagic cell deathGO:0035071830.028
cell deathGO:00082192790.027
regulation of mitotic cell cycleGO:00073461900.027
negative regulation of cell cycle processGO:00109481090.026
negative regulation of cell cycle phase transitionGO:19019881030.026
mitotic sister chromatid segregationGO:0000070870.026
establishment of nucleus localizationGO:0040023260.026
cellular amino acid metabolic processGO:0006520610.026
mitotic dna integrity checkpointGO:0044774750.025
protein phosphorylationGO:00064681690.025
intracellular protein transportGO:00068861040.025
tripartite regional subdivisionGO:00073511030.025
regulation of cellular component movementGO:0051270420.025
zygotic determination of anterior posterior axis embryoGO:0007354270.025
regulation of nervous system developmentGO:00519602480.025
centrosome organizationGO:00512971630.025
negative regulation of nervous system developmentGO:0051961920.025
positive regulation of cell communicationGO:00106472500.024
regulation of intracellular transportGO:0032386640.024
positive regulation of molecular functionGO:00440931360.024
oxidation reduction processGO:00551141230.024
positive regulation of cellular protein metabolic processGO:00322701180.024
response to endoplasmic reticulum stressGO:0034976280.024
carbohydrate derivative metabolic processGO:19011352170.023
axis specificationGO:00097981670.023
oocyte differentiationGO:00099941450.023
cell cycle checkpointGO:0000075950.023
single organismal cell cell adhesionGO:0016337450.023
regulation of cell morphogenesis involved in differentiationGO:0010769610.023
cellular response to endogenous stimulusGO:0071495800.023
nucleoside catabolic processGO:00091641120.023
positive regulation of nucleotide catabolic processGO:0030813460.022
regulation of cell growthGO:0001558430.022
peptidyl threonine phosphorylationGO:001810720.022
positive regulation of gtpase activityGO:0043547430.022
terminal region determinationGO:0007362250.022
regulation of cellular amine metabolic processGO:003323830.022
nuclear divisionGO:00002803320.022
cytoplasmic transportGO:00164821300.022
neurotransmitter gated ion channel clusteringGO:007257820.022
positive regulation of catalytic activityGO:00430851180.022
negative regulation of nucleic acid templated transcriptionGO:19035072400.021
regulation of phosphorus metabolic processGO:00511742100.021
cellular ketone metabolic processGO:0042180240.021
cellular catabolic processGO:00442483720.021
regulation of mitotic cell cycle phase transitionGO:19019901300.021
purine containing compound catabolic processGO:00725231120.021
dna integrity checkpointGO:0031570810.021
ribonucleotide catabolic processGO:00092611090.021
oocyte maturationGO:000155630.021
cellular amine metabolic processGO:0044106120.020
axon guidanceGO:00074112330.020
modification dependent macromolecule catabolic processGO:0043632790.020
regulation of protein metabolic processGO:00512462560.020
regulation of neurogenesisGO:00507671580.020
regulation of protein catabolic processGO:0042176550.020
regulation of cellular protein metabolic processGO:00322682430.020
peptidyl threonine modificationGO:001821030.020
organic cyclic compound catabolic processGO:19013611680.019
establishment of organelle localizationGO:00516561220.019
molting cycleGO:0042303560.019
regulation of hydrolase activityGO:0051336970.019
protein targetingGO:0006605640.019
defense responseGO:00069523000.019
negative regulation of epithelial cell proliferationGO:005068040.019
negative regulation of growthGO:0045926840.018
ovipositionGO:0018991190.018
cellular protein catabolic processGO:0044257830.018
positive regulation of purine nucleotide catabolic processGO:0033123460.018
macromolecular complex assemblyGO:00650032560.018
endothelial cell developmentGO:000188560.018
gland morphogenesisGO:00226121450.018
mesenchymal cell developmentGO:001403110.018
agingGO:00075681430.018
nephron developmentGO:007200630.018
organic substance transportGO:00717022570.018
nucleoside phosphate catabolic processGO:19012921100.018
proteolysis involved in cellular protein catabolic processGO:0051603830.017
regulation of anatomical structure morphogenesisGO:00226032420.017
columnar cuboidal epithelial cell differentiationGO:00020652560.017
open tracheal system developmentGO:00074242040.017
protein complex biogenesisGO:00702712010.017
plasma membrane organizationGO:0007009260.016
organelle localizationGO:00516401480.016
carbohydrate derivative catabolic processGO:19011361180.016
cation homeostasisGO:0055080510.016
purine ribonucleoside triphosphate catabolic processGO:00092071080.016
regulation of response to external stimulusGO:00321011150.016
positive regulation of hydrolase activityGO:0051345780.016
purine nucleoside catabolic processGO:00061521120.016
peptidyl lysine modificationGO:0018205570.016
glycosyl compound metabolic processGO:19016571270.015
epithelial cell developmentGO:00020642740.015
negative regulation of notch signaling pathwayGO:0045746410.015
response to radiationGO:00093141550.015
regulation of protein localizationGO:0032880760.015
regulation of response to woundingGO:1903034190.015
ribose phosphate metabolic processGO:00196931450.015
secretionGO:00469031090.015
small molecule metabolic processGO:00442813050.015
regulation of protein modification processGO:00313991120.015
peripheral nervous system developmentGO:0007422520.015
ubiquitin dependent protein catabolic processGO:0006511780.014
defense response to other organismGO:00985422250.014
oocyte constructionGO:00073081120.014
purine ribonucleoside catabolic processGO:00461301120.014
cell proliferationGO:00082832990.014
regulation of notch signaling pathwayGO:00085931000.014
cellular response to oxygen containing compoundGO:1901701790.014
regulation of cellular localizationGO:00603411360.014
catechol containing compound biosynthetic processGO:000971330.014
molting cycle chitin based cuticleGO:0007591560.014
response to oxidative stressGO:0006979860.014
negative regulation of cell cycleGO:00457861160.014
positive regulation of signalingGO:00230562430.014
sex differentiationGO:0007548810.014
establishment or maintenance of apical basal cell polarityGO:0035088340.014
deathGO:00162652840.013
digestive tract morphogenesisGO:00485461270.013
positive regulation of cellular component organizationGO:00511301560.013
protein complex assemblyGO:00064612000.013
response to other organismGO:00517072930.013
positive regulation of gene expressionGO:00106282900.013
segmentationGO:00352822070.013
germarium derived egg chamber formationGO:00072931010.013
regulation of intracellular protein transportGO:0033157460.013
response to oxygen containing compoundGO:19017002000.013
secretion by cellGO:00329401010.013
regulation of ras protein signal transductionGO:0046578930.013
hemopoiesisGO:0030097460.013
striated muscle myosin thick filament assemblyGO:007168830.013
regulation of stress activated protein kinase signaling cascadeGO:0070302420.013
neuromuscular junction developmentGO:00075281490.013
head developmentGO:00603221350.013
mitotic g2 m transition checkpointGO:0044818700.013
regulation of dendrite developmentGO:0050773370.012
regulation of endopeptidase activityGO:0052548360.012
regulation of cell differentiationGO:00455953020.012
purine nucleoside triphosphate catabolic processGO:00091461080.012
purine ribonucleotide catabolic processGO:00091541090.012
renal tubule developmentGO:0061326640.012
positive regulation of chromosome segregationGO:0051984100.012
protein autophosphorylationGO:0046777150.012
purine ribonucleoside monophosphate metabolic processGO:0009167500.012
regulation of molecular functionGO:00650092170.012
regulation of viral genome replicationGO:004506940.012
purine ribonucleotide metabolic processGO:00091501450.012
ribonucleotide metabolic processGO:00092591450.012
production of molecular mediator of immune responseGO:0002440460.012
hatchingGO:003518840.012
gtp catabolic processGO:0006184720.012
regulation of intracellular signal transductionGO:19025312360.011
ion homeostasisGO:0050801550.011
icosanoid biosynthetic processGO:004645610.011
catabolic processGO:00090564090.011
establishment of protein localization to organelleGO:0072594620.011
small gtpase mediated signal transductionGO:0007264880.011
regulation of transferase activityGO:0051338580.011
cell cycle arrestGO:000705040.011
organelle inheritanceGO:004830820.011
digestive tract developmentGO:00485651490.011
negative regulation of immune system processGO:0002683500.011
imaginal disc growthGO:0007446370.011
activation of innate immune responseGO:000221840.011
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145300.011
regulation of organelle organizationGO:00330431960.011
regulation of reproductive processGO:2000241540.011
stem cell divisionGO:0017145690.011
dna damage checkpointGO:0000077780.011
organophosphate metabolic processGO:00196371950.010
nucleoside metabolic processGO:00091161270.010
regulation of cell divisionGO:0051302720.010
phagocytosisGO:00069092150.010
cellular response to nitrogen compoundGO:1901699510.010
metal ion homeostasisGO:0055065440.010
mushroom body developmentGO:0016319700.010
response to nitrogen compoundGO:1901698900.010
regulation of cell proliferationGO:00421271630.010
negative regulation of signal transduction by p53 class mediatorGO:190179710.010
negative regulation of cellular component organizationGO:00511291080.010
chemical homeostasisGO:0048878920.010

trol disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.021
cancerDOID:16200.021
disease of anatomical entityDOID:700.014