IMP: Integrative Multi-species Prediction

Drosophila melanogaster

47 known processes

cp309 (Dmel_CG33957)

CG33957 gene product from transcript CG33957-RB

(Aliases: PACT,CG33957,dplp,CG18648,PLP,dPLP,D-PLP,Plp,Cp309,Dmel\CG33957,pPlp,d-plp,CP309,CG13459,AKAP450,l(3)s2172,DPLP,CG6735)

FLYBASE: FBgn0086690
Entrez: 3772382
UniProtKB: M9PFP4
UniProtKB: M9PFP0
UniProtKB: M9ND93
UniProtKB: Q400N2
UniProtKB: Q400N1
UniProtKB: M9PI63
UniProtKB: M9NFV3
UniProtKB: M9PCJ5
UniProtKB: M9PFJ2
UniProtKB: M9PCK2
UniProtKB: M9PFA8
UniProtKB: M9PFA3

Process Predictions
Disease Predictions

cp309 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
single organism behavior	GO:0044708	391	0.819
response to mechanical stimulus	GO:0009612	28	0.772
multicellular organismal reproductive behavior	GO:0033057	110	0.710
response to auditory stimulus	GO:0010996	5	0.706
auditory behavior	GO:0031223	1	0.446
multi organism reproductive behavior	GO:0044705	121	0.380
response to abiotic stimulus	GO:0009628	341	0.378
mechanosensory behavior	GO:0007638	12	0.361
male courtship behavior	GO:0008049	63	0.308
centrosome organization	GO:0051297	163	0.226
multi multicellular organism process	GO:0044706	123	0.191
male mating behavior	GO:0060179	70	0.188
cilium morphogenesis	GO:0060271	39	0.183
organelle assembly	GO:0070925	198	0.181
mating	GO:0007618	120	0.179
dendrite development	GO:0016358	204	0.172
microtubule organizing center organization	GO:0031023	168	0.160
centrosome cycle	GO:0007098	137	0.154
centrosome duplication	GO:0051298	121	0.153
sensory perception of mechanical stimulus	GO:0050954	72	0.133
mitotic spindle organization	GO:0007052	220	0.124
reproductive behavior	GO:0019098	122	0.120
regulation of molecular function	GO:0065009	217	0.113
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.113
nuclear division	GO:0000280	332	0.109
courtship behavior	GO:0007619	68	0.108
sensory perception	GO:0007600	196	0.108
axon guidance	GO:0007411	233	0.096
taxis	GO:0042330	304	0.095
mating behavior	GO:0007617	106	0.094
single organism cellular localization	GO:1902580	180	0.093
cellular macromolecule localization	GO:0070727	220	0.082
adult locomotory behavior	GO:0008344	76	0.081
post embryonic appendage morphogenesis	GO:0035120	385	0.077
segmentation	GO:0035282	207	0.076
appendage development	GO:0048736	401	0.072
imaginal disc derived appendage development	GO:0048737	399	0.071
sensory organ morphogenesis	GO:0090596	260	0.070
mitotic nuclear division	GO:0007067	213	0.069
organelle fission	GO:0048285	340	0.068
wing disc morphogenesis	GO:0007472	344	0.067
positive regulation of cellular component organization	GO:0051130	156	0.066
locomotory behavior	GO:0007626	176	0.065
organelle localization	GO:0051640	148	0.064
axonogenesis	GO:0007409	290	0.064
neuron projection guidance	GO:0097485	241	0.062
sensory perception of sound	GO:0007605	56	0.060
small molecule metabolic process	GO:0044281	305	0.059
regionalization	GO:0003002	416	0.055
eye photoreceptor cell differentiation	GO:0001754	145	0.054
head development	GO:0060322	135	0.054
asymmetric neuroblast division	GO:0055059	33	0.053
embryonic development via the syncytial blastoderm	GO:0001700	148	0.052
neurological system process	GO:0050877	358	0.052
salivary gland morphogenesis	GO:0007435	145	0.051
regulation of neurogenesis	GO:0050767	158	0.051
forebrain development	GO:0030900	2	0.050
sister chromatid segregation	GO:0000819	92	0.050
protein complex assembly	GO:0006461	200	0.050
positive regulation of macromolecule metabolic process	GO:0010604	405	0.049
response to biotic stimulus	GO:0009607	294	0.048
meiotic cell cycle	GO:0051321	171	0.047
centriole assembly	GO:0098534	24	0.047
brain development	GO:0007420	120	0.045
vesicle mediated transport	GO:0016192	381	0.045
adult behavior	GO:0030534	137	0.045
embryo development ending in birth or egg hatching	GO:0009792	152	0.045
regulation of organelle organization	GO:0033043	196	0.044
organonitrogen compound metabolic process	GO:1901564	318	0.043
regulation of rna splicing	GO:0043484	69	0.043
centriole replication	GO:0007099	24	0.043
glycosyl compound metabolic process	GO:1901657	127	0.042
regulation of cell projection organization	GO:0031344	92	0.042
macromolecular complex assembly	GO:0065003	256	0.042
detection of stimulus	GO:0051606	156	0.041
regulation of cell cycle process	GO:0010564	181	0.040
multi organism behavior	GO:0051705	175	0.040
axon development	GO:0061564	297	0.039
catabolic process	GO:0009056	409	0.038
regulation of microtubule cytoskeleton organization	GO:0070507	41	0.038
telencephalon development	GO:0021537	2	0.037
compound eye photoreceptor fate commitment	GO:0001752	36	0.036
organic substance transport	GO:0071702	257	0.036
chromosome organization	GO:0051276	360	0.035
cell maturation	GO:0048469	144	0.035
immune system process	GO:0002376	347	0.035
microtubule based transport	GO:0010970	42	0.035
regulation of multi organism process	GO:0043900	131	0.034
developmental growth	GO:0048589	280	0.034
cell projection assembly	GO:0030031	94	0.033
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.032
dendrite morphogenesis	GO:0048813	199	0.032
regulation of cell differentiation	GO:0045595	302	0.032
actin filament based process	GO:0030029	220	0.032
intracellular protein transport	GO:0006886	104	0.032
microtubule cytoskeleton organization involved in mitosis	GO:1902850	52	0.032
ras protein signal transduction	GO:0007265	88	0.032
positive regulation of rna metabolic process	GO:0051254	271	0.032
regulation of intracellular signal transduction	GO:1902531	236	0.031
regulation of catalytic activity	GO:0050790	185	0.031
eye morphogenesis	GO:0048592	260	0.031
regulation of cell cycle phase transition	GO:1901987	130	0.031
chemotaxis	GO:0006935	249	0.031
spindle assembly	GO:0051225	80	0.030
regulation of anatomical structure morphogenesis	GO:0022603	242	0.030
regulation of cell morphogenesis	GO:0022604	163	0.030
compound eye photoreceptor cell differentiation	GO:0001751	140	0.029
carbohydrate derivative metabolic process	GO:1901135	217	0.028
cell division	GO:0051301	248	0.028
death	GO:0016265	284	0.028
regulation of mitosis	GO:0007088	56	0.028
purine ribonucleotide metabolic process	GO:0009150	145	0.028
endocytosis	GO:0006897	310	0.028
regulation of cytoskeleton organization	GO:0051493	89	0.027
regulation of cell division	GO:0051302	72	0.027
regulation of alternative mrna splicing via spliceosome	GO:0000381	60	0.027
anatomical structure homeostasis	GO:0060249	97	0.027
detection of external stimulus	GO:0009581	66	0.027
chemosensory behavior	GO:0007635	106	0.026
neuronal stem cell division	GO:0036445	35	0.026
centrosome separation	GO:0051299	20	0.026
cilium organization	GO:0044782	41	0.026
positive regulation of rna biosynthetic process	GO:1902680	266	0.025
cellular component assembly involved in morphogenesis	GO:0010927	151	0.025
establishment of organelle localization	GO:0051656	122	0.025
regulation of cellular ketone metabolic process	GO:0010565	3	0.025
regulation of microtubule based process	GO:0032886	49	0.025
appendage morphogenesis	GO:0035107	397	0.025
single organism catabolic process	GO:0044712	228	0.025
small gtpase mediated signal transduction	GO:0007264	88	0.024
embryonic morphogenesis	GO:0048598	206	0.024
photoreceptor cell development	GO:0042461	96	0.024
organonitrogen compound catabolic process	GO:1901565	128	0.024
maintenance of location	GO:0051235	73	0.024
spindle assembly involved in mitosis	GO:0090307	50	0.023
choline catabolic process	GO:0042426	1	0.023
organic substance catabolic process	GO:1901575	308	0.023
response to heat	GO:0009408	63	0.023
oxidation reduction process	GO:0055114	123	0.023
regulation of cell morphogenesis involved in differentiation	GO:0010769	61	0.023
mitotic cell cycle embryonic	GO:0045448	38	0.022
neuron projection extension	GO:1990138	32	0.022
establishment of blood nerve barrier	GO:0008065	2	0.022
body morphogenesis	GO:0010171	2	0.022
organonitrogen compound biosynthetic process	GO:1901566	117	0.022
growth	GO:0040007	359	0.022
imaginal disc derived wing morphogenesis	GO:0007476	337	0.022
pronuclear migration	GO:0035046	4	0.021
glial cell development	GO:0021782	27	0.021
protein localization	GO:0008104	284	0.021
positive regulation of transport	GO:0051050	92	0.021
neuroblast division	GO:0055057	35	0.021
cell fate commitment involved in pattern specification	GO:0060581	31	0.021
positive regulation of response to stimulus	GO:0048584	323	0.021
cellular protein localization	GO:0034613	160	0.021
regulation of developmental growth	GO:0048638	174	0.021
mitotic cell cycle checkpoint	GO:0007093	88	0.021
fertilization	GO:0009566	26	0.020
regulation of protein metabolic process	GO:0051246	256	0.020
flight behavior	GO:0007629	26	0.020
neuron recognition	GO:0008038	101	0.020
regulation of catabolic process	GO:0009894	170	0.020
protein localization to organelle	GO:0033365	82	0.020
jak stat cascade	GO:0007259	49	0.020
epithelial cell development	GO:0002064	274	0.020
intracellular signal transduction	GO:0035556	300	0.020
establishment or maintenance of microtubule cytoskeleton polarity	GO:0030951	41	0.019
regulation of phosphorus metabolic process	GO:0051174	210	0.019
response to external biotic stimulus	GO:0043207	293	0.019
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.019
protein transport	GO:0015031	155	0.019
cellular ketone metabolic process	GO:0042180	24	0.019
regulation of metaphase anaphase transition of cell cycle	GO:1902099	26	0.019
actin cytoskeleton organization	GO:0030036	206	0.018
oxoacid metabolic process	GO:0043436	103	0.018
carboxylic acid metabolic process	GO:0019752	92	0.018
positive regulation of phosphate metabolic process	GO:0045937	139	0.018
regulation of cell development	GO:0060284	215	0.018
metaphase anaphase transition of mitotic cell cycle	GO:0007091	28	0.018
neural precursor cell proliferation	GO:0061351	75	0.018
establishment of protein localization	GO:0045184	163	0.017
embryonic pattern specification	GO:0009880	174	0.017
photoreceptor cell differentiation	GO:0046530	170	0.017
regulation of mitotic cell cycle	GO:0007346	190	0.017
compound eye development	GO:0048749	307	0.017
gtp catabolic process	GO:0006184	72	0.017
sperm motility	GO:0030317	12	0.017
regulation of mitotic sister chromatid segregation	GO:0033047	28	0.017
response to inorganic substance	GO:0010035	44	0.017
rna processing	GO:0006396	147	0.017
regulation of neuron projection development	GO:0010975	69	0.017
spermatogenesis	GO:0007283	200	0.017
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.016
ribonucleotide metabolic process	GO:0009259	145	0.016
proteolysis	GO:0006508	192	0.016
regulation of hydrolase activity	GO:0051336	97	0.016
phagocytosis	GO:0006909	215	0.016
homeostatic process	GO:0042592	199	0.016
regulation of cellular catabolic process	GO:0031329	157	0.016
humoral immune response	GO:0006959	117	0.016
response to oxygen containing compound	GO:1901700	200	0.016
oocyte maturation	GO:0001556	3	0.016
cell fate determination	GO:0001709	91	0.016
cell growth	GO:0016049	108	0.016
gland development	GO:0048732	191	0.016
chromosome segregation	GO:0007059	157	0.015
establishment or maintenance of cell polarity	GO:0007163	167	0.015
intercellular transport	GO:0010496	2	0.015
positive regulation of catalytic activity	GO:0043085	118	0.015
regulation of multicellular organismal development	GO:2000026	414	0.015
lipid localization	GO:0010876	54	0.015
mitotic sister chromatid separation	GO:0051306	30	0.015
ribose phosphate metabolic process	GO:0019693	145	0.015
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.015
single organism intracellular transport	GO:1902582	207	0.015
regulation of cellular protein catabolic process	GO:1903362	44	0.015
learning or memory	GO:0007611	141	0.015
organophosphate metabolic process	GO:0019637	195	0.015
phototaxis	GO:0042331	21	0.015
cellular catabolic process	GO:0044248	372	0.015
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.015
heterocycle catabolic process	GO:0046700	166	0.015
positive regulation of gene expression	GO:0010628	290	0.015
peptidyl threonine phosphorylation	GO:0018107	2	0.015
necrotic cell death	GO:0070265	1	0.015
actin filament based movement	GO:0030048	26	0.014
regulation of cell cycle	GO:0051726	291	0.014
positive regulation of cell cycle process	GO:0090068	28	0.014
regulation of proteolysis	GO:0030162	87	0.014
cell death	GO:0008219	279	0.014
regulation of response to external stimulus	GO:0032101	115	0.014
mrna processing	GO:0006397	104	0.014
spindle organization	GO:0007051	253	0.014
cell cycle comprising mitosis without cytokinesis	GO:0033301	25	0.014
cell adhesion	GO:0007155	136	0.014
actin filament organization	GO:0007015	126	0.014
cellular response to biotic stimulus	GO:0071216	4	0.014
motor neuron axon guidance	GO:0008045	58	0.014
salivary gland development	GO:0007431	162	0.014
regulation of mrna processing	GO:0050684	71	0.013
purine nucleotide metabolic process	GO:0006163	146	0.013
peptidyl threonine modification	GO:0018210	3	0.013
positive regulation of biosynthetic process	GO:0009891	316	0.013
receptor mediated endocytosis	GO:0006898	21	0.013
somatic stem cell division	GO:0048103	37	0.013
axoneme assembly	GO:0035082	18	0.013
wnt signaling pathway	GO:0016055	98	0.013
gland morphogenesis	GO:0022612	145	0.013
negative regulation of organelle organization	GO:0010639	56	0.013
asymmetric stem cell division	GO:0098722	49	0.013
nucleoside triphosphate catabolic process	GO:0009143	108	0.013
blastoderm segmentation	GO:0007350	159	0.013
spermatid differentiation	GO:0048515	114	0.013
regulation of mitotic metaphase anaphase transition	GO:0030071	26	0.013
developmental growth involved in morphogenesis	GO:0060560	65	0.013
regulation of neuron differentiation	GO:0045664	103	0.013
regulation of embryonic development	GO:0045995	68	0.013
regulation of protein localization	GO:0032880	76	0.013
establishment of vesicle localization	GO:0051650	51	0.013
localization of cell	GO:0051674	257	0.013
generation of precursor metabolites and energy	GO:0006091	42	0.013
regulation of cellular amine metabolic process	GO:0033238	3	0.013
regulation of cellular component size	GO:0032535	98	0.013
regulation of vesicle mediated transport	GO:0060627	59	0.013
regulation of axonogenesis	GO:0050770	32	0.013
acetate ester metabolic process	GO:1900619	2	0.012
imaginal disc derived wing hair organization	GO:0035317	45	0.012
energy taxis	GO:0009453	21	0.012
regulation of transmembrane transporter activity	GO:0022898	6	0.012
regulation of nervous system development	GO:0051960	248	0.012
asymmetric cell division	GO:0008356	37	0.012
non sensory hair organization	GO:0035316	47	0.012
establishment of blood brain barrier	GO:0060856	16	0.012
regulation of mrna splicing via spliceosome	GO:0048024	64	0.012
photoreceptor cell fate commitment	GO:0046552	41	0.012
macromolecule catabolic process	GO:0009057	161	0.012
nucleoside triphosphate metabolic process	GO:0009141	120	0.012
compound eye photoreceptor development	GO:0042051	78	0.012
cranial nerve development	GO:0021545	1	0.012
response to light stimulus	GO:0009416	124	0.012
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.012
nucleobase containing small molecule metabolic process	GO:0055086	174	0.012
nucleoside phosphate metabolic process	GO:0006753	162	0.012
positive regulation of cell projection organization	GO:0031346	29	0.012
larval development	GO:0002164	104	0.012
cellular protein catabolic process	GO:0044257	83	0.012
organic cyclic compound catabolic process	GO:1901361	168	0.012
metaphase anaphase transition of cell cycle	GO:0044784	28	0.012
purine containing compound metabolic process	GO:0072521	155	0.012
nuclear migration	GO:0007097	20	0.011
cellular response to dna damage stimulus	GO:0006974	223	0.011
organic acid metabolic process	GO:0006082	103	0.011
somatic muscle development	GO:0007525	66	0.011
protein catabolic process	GO:0030163	101	0.011
transcription from rna polymerase ii promoter	GO:0006366	368	0.011
regulation of cellular component biogenesis	GO:0044087	201	0.011
biological adhesion	GO:0022610	138	0.011
chromosome separation	GO:0051304	42	0.011
regulation of dendrite development	GO:0050773	37	0.011
vesicle localization	GO:0051648	55	0.011
protein maturation	GO:0051604	71	0.011
negative regulation of gene expression	GO:0010629	387	0.011
regulation of membrane potential	GO:0042391	35	0.011
eye photoreceptor cell development	GO:0042462	81	0.011
positive regulation of cellular protein metabolic process	GO:0032270	118	0.011
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process	GO:0031145	30	0.011
establishment of nucleus localization	GO:0040023	26	0.011
proteasomal protein catabolic process	GO:0010498	59	0.011
response to radiation	GO:0009314	155	0.011
glycosyl compound catabolic process	GO:1901658	112	0.011
regulation of mrna metabolic process	GO:1903311	72	0.011
programmed cell death	GO:0012501	257	0.011
hormone catabolic process	GO:0042447	3	0.011
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.011
androgen metabolic process	GO:0008209	1	0.011
purine nucleoside catabolic process	GO:0006152	112	0.011
ribonucleoside catabolic process	GO:0042454	112	0.011
protein phosphorylation	GO:0006468	169	0.011
development of primary sexual characteristics	GO:0045137	50	0.011
developmental programmed cell death	GO:0010623	138	0.011
membrane organization	GO:0061024	112	0.011
dorsal closure	GO:0007391	79	0.011
positive regulation of cell development	GO:0010720	61	0.011
mitotic sister chromatid segregation	GO:0000070	87	0.011
developmental cell growth	GO:0048588	52	0.011
acid secretion	GO:0046717	1	0.011
cellular response to molecule of bacterial origin	GO:0071219	3	0.011
single organism nuclear import	GO:1902593	51	0.011
compound eye morphogenesis	GO:0001745	249	0.010
positive regulation of signal transduction	GO:0009967	223	0.010
limb development	GO:0060173	1	0.010
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.010
positive regulation of developmental growth	GO:0048639	62	0.010
nucleoside catabolic process	GO:0009164	112	0.010
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.010
regulation of g protein coupled receptor protein signaling pathway	GO:0008277	23	0.010
response to lipopolysaccharide	GO:0032496	4	0.010
regulation of epithelial cell proliferation	GO:0050678	4	0.010
nucleotide catabolic process	GO:0009166	109	0.010
regulation of cell death	GO:0010941	173	0.010
mrna splicing via spliceosome	GO:0000398	73	0.010
positive regulation of cell cycle	GO:0045787	43	0.010
nucleus organization	GO:0006997	45	0.010
regulation of protein processing	GO:0070613	32	0.010
epithelial cell differentiation	GO:0030855	322	0.010

cp309 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of cellular proliferation	DOID:14566	0.022
organ system cancer	DOID:0050686	0.022
cancer	DOID:162	0.022
disease of anatomical entity	DOID:7	0.011
nervous system disease	DOID:863	0.010

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