Drosophila melanogaster

95 known processes

brn (Dmel_CG4934)

brainiac

(Aliases: EG:EG0007.6,fs(1)107,fs(1)A107,Dmel\CG4934,l(1)6P6,CG4934,brc)

brn biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
axonogenesisGO:00074092900.646
chemotaxisGO:00069352490.561
taxisGO:00423303040.484
neuron projection guidanceGO:00974852410.469
axon developmentGO:00615642970.355
positive regulation of nitrogen compound metabolic processGO:00511733540.321
axon guidanceGO:00074112330.280
positive regulation of macromolecule biosynthetic processGO:00105572830.264
positive regulation of gene expressionGO:00106282900.249
positive regulation of cellular biosynthetic processGO:00313283160.232
regulation of cell differentiationGO:00455953020.157
intracellular signal transductionGO:00355563000.156
regulation of intracellular signal transductionGO:19025312360.154
positive regulation of nucleobase containing compound metabolic processGO:00459353320.154
positive regulation of response to stimulusGO:00485843230.143
positive regulation of macromolecule metabolic processGO:00106044050.119
regulation of transcription from rna polymerase ii promoterGO:00063573780.115
regionalizationGO:00030024160.111
regulation of cell morphogenesisGO:00226041630.105
regulation of phosphate metabolic processGO:00192202100.102
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.100
ovarian follicle cell developmentGO:00307072480.095
stem cell differentiationGO:00488631170.087
phosphorylationGO:00163102940.086
cellular protein modification processGO:00064644380.086
positive regulation of signal transductionGO:00099672230.086
positive regulation of biosynthetic processGO:00098913160.085
positive regulation of signalingGO:00230562430.085
regulation of multi organism processGO:00439001310.084
appendage morphogenesisGO:00351073970.084
regulation of cell cycleGO:00517262910.083
immune system processGO:00023763470.082
positive regulation of nucleic acid templated transcriptionGO:19035082660.082
digestive tract morphogenesisGO:00485461270.082
central nervous system developmentGO:00074172010.078
transcription from rna polymerase ii promoterGO:00063663680.076
negative regulation of signalingGO:00230572190.076
regulation of notch signaling pathwayGO:00085931000.073
appendage developmentGO:00487364010.072
cell migrationGO:00164772380.072
wing disc morphogenesisGO:00074723440.072
camera type eye developmentGO:004301040.071
notch signaling pathwayGO:00072191200.068
embryonic morphogenesisGO:00485982060.067
positive regulation of rna metabolic processGO:00512542710.066
imaginal disc derived appendage morphogenesisGO:00351143950.064
compound eye photoreceptor cell differentiationGO:00017511400.064
cell fate specificationGO:0001708710.063
vesicle mediated transportGO:00161923810.062
protein phosphorylationGO:00064681690.061
protein modification processGO:00362114380.059
tube morphogenesisGO:00352391910.059
gland developmentGO:00487321910.057
epithelial cell developmentGO:00020642740.057
response to abiotic stimulusGO:00096283410.056
sensory organ morphogenesisGO:00905962600.056
intracellular transportGO:00469072280.055
positive regulation of cell communicationGO:00106472500.055
regulation of immune system processGO:00026821760.054
regulation of cell developmentGO:00602842150.052
tube developmentGO:00352952440.052
body morphogenesisGO:001017120.051
positive regulation of transcription dna templatedGO:00458932660.049
epithelial cell differentiationGO:00308553220.049
response to other organismGO:00517072930.048
immune effector processGO:0002252980.048
negative regulation of gene expressionGO:00106293870.048
reproductive behaviorGO:00190981220.048
cuticle pattern formationGO:0035017270.048
regulation of multicellular organismal developmentGO:20000264140.047
morphogenesis of an epitheliumGO:00020092760.047
cellular amine metabolic processGO:0044106120.046
regulation of cell cycle processGO:00105641810.046
single organism behaviorGO:00447083910.046
regulation of localizationGO:00328792750.045
cytoplasmic transportGO:00164821300.044
digestive tract developmentGO:00485651490.044
cell fate determinationGO:0001709910.044
imaginal disc derived wing morphogenesisGO:00074763370.044
neurological system processGO:00508773580.044
negative regulation of phosphorus metabolic processGO:0010563450.044
regulation of cell projection organizationGO:0031344920.043
cellular catabolic processGO:00442483720.043
nephron tubule developmentGO:007208030.042
regulation of protein metabolic processGO:00512462560.042
regulation of phosphorus metabolic processGO:00511742100.042
cell projection assemblyGO:0030031940.041
regulation of cellular amino acid metabolic processGO:000652100.041
negative regulation of biosynthetic processGO:00098902770.040
organonitrogen compound metabolic processGO:19015643180.040
dna metabolic processGO:00062592270.039
imaginal disc derived appendage developmentGO:00487373990.039
meiotic cell cycle processGO:19030461320.039
negative regulation of phosphate metabolic processGO:0045936450.039
post embryonic appendage morphogenesisGO:00351203850.038
regulation of nervous system developmentGO:00519602480.038
dendrite morphogenesisGO:00488131990.038
asymmetric cell divisionGO:0008356370.038
cytokinesisGO:0000910900.037
blastoderm segmentationGO:00073501590.037
brain developmentGO:00074201200.037
protein complex biogenesisGO:00702712010.037
signal transduction by phosphorylationGO:00230141070.037
phagocytosisGO:00069092150.037
embryo development ending in birth or egg hatchingGO:00097921520.036
regulation of cellular amine metabolic processGO:003323830.036
cell proliferationGO:00082832990.036
amine metabolic processGO:0009308120.036
actin cytoskeleton organizationGO:00300362060.036
organelle fissionGO:00482853400.036
segmentationGO:00352822070.035
cellular amino acid metabolic processGO:0006520610.034
exocrine system developmentGO:00352721620.034
regulation of mapk cascadeGO:0043408920.034
imaginal disc pattern formationGO:0007447910.033
cell divisionGO:00513012480.033
regulation of molecular functionGO:00650092170.033
retina development in camera type eyeGO:006004140.033
multi organism behaviorGO:00517051750.033
regulation of cell deathGO:00109411730.033
eggshell chorion assemblyGO:0007306660.032
regulation of anatomical structure sizeGO:00900661630.032
dendrite developmentGO:00163582040.032
embryonic development via the syncytial blastodermGO:00017001480.031
mapk cascadeGO:00001651070.031
renal system developmentGO:0072001720.031
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.031
mitotic nuclear divisionGO:00070672130.031
kidney developmentGO:000182230.030
negative regulation of phosphorylationGO:0042326350.030
oxoacid metabolic processGO:00434361030.030
protein localizationGO:00081042840.029
positive regulation of cell migrationGO:003033520.029
eye developmentGO:00016543230.028
neuron recognitionGO:00080381010.028
negative regulation of cell communicationGO:00106482230.028
negative regulation of cellular metabolic processGO:00313243820.028
regulation of reproductive processGO:2000241540.027
regulation of microtubule cytoskeleton organizationGO:0070507410.027
lateral inhibitionGO:00463312060.027
ameboidal type cell migrationGO:00016671510.027
nucleus localizationGO:0051647340.026
endodermal cell fate commitmentGO:000171130.026
sensory perceptionGO:00076001960.026
formation of organ boundaryGO:0010160300.026
developmental programmed cell deathGO:00106231380.026
response to organic substanceGO:00100332840.026
regulation of cellular localizationGO:00603411360.026
negative regulation of nucleobase containing compound metabolic processGO:00459342610.026
regulation of neurogenesisGO:00507671580.026
stem cell maintenanceGO:0019827670.025
renal tubule morphogenesisGO:0061333440.025
negative regulation of organelle organizationGO:0010639560.025
actin filament based processGO:00300292200.025
negative regulation of notch signaling pathwayGO:0045746410.025
regulation of cellular component biogenesisGO:00440872010.025
cell adhesionGO:00071551360.025
negative regulation of multicellular organismal processGO:00512411420.025
negative regulation of rna biosynthetic processGO:19026792400.025
positive regulation of rna biosynthetic processGO:19026802660.025
multi multicellular organism processGO:00447061230.024
regulation of catalytic activityGO:00507901850.024
cellular lipid metabolic processGO:0044255830.024
cellular protein localizationGO:00346131600.023
cell motilityGO:00488702510.023
dorsal appendage formationGO:0046843470.023
response to biotic stimulusGO:00096072940.023
positive regulation of developmental processGO:00510941430.023
eye morphogenesisGO:00485922600.023
carboxylic acid metabolic processGO:0019752920.023
regulation of catabolic processGO:00098941700.023
wnt signaling pathwayGO:0016055980.023
cell cycle arrestGO:000705040.023
sex determinationGO:0007530180.023
regulation of organelle organizationGO:00330431960.022
regulation of phosphorylationGO:00423251470.022
peptidyl amino acid modificationGO:00181931050.022
negative regulation of signal transductionGO:00099682060.022
regulation of organ morphogenesisGO:2000027780.022
regulation of microtubule polymerization or depolymerizationGO:0031110270.022
regulation of neuron differentiationGO:00456641030.022
organic substance transportGO:00717022570.022
cellular macromolecule catabolic processGO:00442651360.022
negative regulation of rna metabolic processGO:00512532510.022
nuclear divisionGO:00002803320.022
phenol containing compound metabolic processGO:0018958570.022
defense responseGO:00069523000.021
spindle organizationGO:00070512530.021
regulation of microtubule based processGO:0032886490.021
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.021
eye photoreceptor cell developmentGO:0042462810.021
cellular ketone metabolic processGO:0042180240.021
ubiquitin dependent protein catabolic processGO:0006511780.021
negative regulation of response to stimulusGO:00485852580.021
dorsal ventral pattern formationGO:00099531330.021
small molecule metabolic processGO:00442813050.021
renal tubule developmentGO:0061326640.021
cell cell signaling involved in cell fate commitmentGO:00451682100.021
regulation of mitotic cell cycle phase transitionGO:19019901300.020
positive regulation of cell motilityGO:200014730.020
embryonic axis specificationGO:00005781070.020
membrane organizationGO:00610241120.020
mitotic spindle organizationGO:00070522200.020
regulation of transportGO:00510491810.020
eye photoreceptor cell differentiationGO:00017541450.020
regulation of cellular ketone metabolic processGO:001056530.020
salivary gland morphogenesisGO:00074351450.020
negative regulation of cellular component organizationGO:00511291080.020
regulation of epithelial cell proliferationGO:005067840.020
rna splicingGO:0008380830.019
leg disc developmentGO:0035218920.019
regulation of protein complex disassemblyGO:0043244290.019
regulation of cell divisionGO:0051302720.019
regulation of cell morphogenesis involved in differentiationGO:0010769610.019
posttranscriptional regulation of gene expressionGO:00106081450.019
mesoderm developmentGO:0007498780.019
regulation of cellular catabolic processGO:00313291570.019
negative regulation of cellular protein metabolic processGO:0032269850.019
antimicrobial humoral responseGO:0019730990.019
establishment of localization in cellGO:00516494020.019
rna processingGO:00063961470.019
regulation of i kappab kinase nf kappab signalingGO:004312220.019
microtubule based movementGO:0007018510.019
wing disc pattern formationGO:0035222660.019
cytoskeleton dependent intracellular transportGO:0030705440.019
cytoskeleton dependent cytokinesisGO:0061640810.019
endodermal cell differentiationGO:003598730.019
humoral immune responseGO:00069591170.018
catabolic processGO:00090564090.018
single organism catabolic processGO:00447122280.018
regulation of ras protein signal transductionGO:0046578930.018
negative regulation of protein metabolic processGO:0051248850.018
regulation of protein transportGO:0051223570.018
negative regulation of nucleic acid templated transcriptionGO:19035072400.018
kidney epithelium developmentGO:007207330.018
regulation of protein phosphorylationGO:0001932640.018
positive regulation of cell differentiationGO:0045597640.018
negative regulation of protein modification processGO:0031400290.018
negative regulation of cell cycleGO:00457861160.018
chorion containing eggshell formationGO:00073041050.017
hematopoietic progenitor cell differentiationGO:000224410.017
negative regulation of developmental processGO:00510932010.017
establishment of organelle localizationGO:00516561220.017
salivary gland developmentGO:00074311620.017
gastrulationGO:0007369700.017
nephron epithelium morphogenesisGO:007208830.017
negative regulation of cytoskeleton organizationGO:0051494300.017
positive regulation of catabolic processGO:00098961050.017
organelle localizationGO:00516401480.017
immune responseGO:00069552460.017
mesenchymal cell differentiationGO:004876210.017
embryonic pattern specificationGO:00098801740.017
small gtpase mediated signal transductionGO:0007264880.017
negative regulation of protein complex disassemblyGO:0043242230.017
regulation of cellular protein metabolic processGO:00322682430.017
single organismal cell cell adhesionGO:0016337450.017
protein palmitoylationGO:001834520.017
embryonic hindgut morphogenesisGO:0048619480.017
protein complex assemblyGO:00064612000.017
nephron epithelium developmentGO:007200930.016
negative regulation of cell cycle processGO:00109481090.016
defense response to other organismGO:00985422250.016
regulation of intracellular transportGO:0032386640.016
microtubule based transportGO:0010970420.016
negative regulation of microtubule depolymerizationGO:0007026210.016
positive regulation of catalytic activityGO:00430851180.016
secretionGO:00469031090.016
regulation of protein complex assemblyGO:0043254420.016
gliogenesisGO:0042063800.016
modification dependent protein catabolic processGO:0019941780.016
regulation of embryonic developmentGO:0045995680.016
photoreceptor cell developmentGO:0042461960.016
cellular nitrogen compound catabolic processGO:00442701650.016
endocytosisGO:00068973100.016
hematopoietic or lymphoid organ developmentGO:0048534570.016
digestive system developmentGO:00551231490.016
nephron developmentGO:007200630.016
regulation of protein localizationGO:0032880760.016
positive regulation of intracellular signal transductionGO:19025331160.016
regulation of mitotic cell cycleGO:00073461900.015
epithelial tube morphogenesisGO:0060562880.015
cellular response to chemical stimulusGO:00708871990.015
negative regulation of macromolecule biosynthetic processGO:00105582700.015
negative regulation of mitotic cell cycle phase transitionGO:19019911030.015
positive regulation of transportGO:0051050920.015
cellular response to dna damage stimulusGO:00069742230.015
organic acid metabolic processGO:00060821030.015
hindgut morphogenesisGO:0007442580.015
hemopoiesisGO:0030097460.015
anterior posterior pattern specificationGO:00099521360.015
head developmentGO:00603221350.015
organic substance catabolic processGO:19015753080.015
regulation of immune responseGO:00507761180.015
regulation of mitosisGO:0007088560.015
kidney morphogenesisGO:006099330.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.015
positive regulation of i kappab kinase nf kappab signalingGO:004312310.015
negative regulation of nitrogen compound metabolic processGO:00511722650.014
nucleotide metabolic processGO:00091171610.014
ras protein signal transductionGO:0007265880.014
cell fate commitment involved in formation of primary germ layerGO:0060795100.014
programmed cell deathGO:00125012570.014
organic cyclic compound catabolic processGO:19013611680.014
positive regulation of cell deathGO:0010942690.014
regulation of protein depolymerizationGO:1901879270.014
positive regulation of cellular catabolic processGO:0031331950.014
deathGO:00162652840.014
stem cell developmentGO:0048864790.014
protein heterooligomerizationGO:005129140.014
regulation of response to stressGO:00801342000.014
peripheral nervous system developmentGO:0007422520.014
negative regulation of protein depolymerizationGO:1901880230.013
apoptotic processGO:00069151590.013
positive regulation of molecular functionGO:00440931360.013
cell cycle phase transitionGO:00447701400.013
response to organophosphorusGO:004668320.013
actin filament organizationGO:00070151260.013
mitotic cytokinesisGO:0000281500.013
regulation of pole plasm oskar mrna localizationGO:0007317270.013
negative regulation of transcription dna templatedGO:00458922370.013
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101180.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.013
wound healingGO:0042060750.013
positive regulation of cellular amino acid metabolic processGO:004576400.013
dna templated transcription elongationGO:0006354180.013
cell deathGO:00082192790.013
cuticle developmentGO:0042335860.013
nucleoside phosphate metabolic processGO:00067531620.013
female sex differentiationGO:0046660200.013
asymmetric protein localizationGO:0008105330.013
establishment of nucleus localizationGO:0040023260.013
locomotory behaviorGO:00076261760.013
reproductive system developmentGO:0061458740.013
molting cycleGO:0042303560.012
immune response activating signal transductionGO:000275720.012
negative regulation of cell proliferationGO:0008285690.012
purine ribonucleotide metabolic processGO:00091501450.012
gland morphogenesisGO:00226121450.012
protein complex disassemblyGO:0043241360.012
nephron tubule morphogenesisGO:007207830.012
regulation of production of molecular mediator of immune responseGO:0002700440.012
ovipositionGO:0018991190.012
response to oxygen containing compoundGO:19017002000.012
gonad developmentGO:0008406500.012
regulation of cytoplasmic transportGO:1903649470.012
positive regulation of protein transportGO:0051222370.012
response to alcoholGO:0097305950.012
regulation of establishment of protein localizationGO:0070201610.012
hindbrain developmentGO:003090220.012
photoreceptor cell differentiationGO:00465301700.012
negative regulation of protein phosphorylationGO:0001933170.012
proteolysisGO:00065081920.012
protein localization to organelleGO:0033365820.012
regulation of wnt signaling pathwayGO:0030111680.012
regulation of defense responseGO:00313471020.012
imaginal disc derived leg morphogenesisGO:0007480800.012
sex differentiationGO:0007548810.012
protein import into nucleusGO:0006606510.011
protein localization to nucleusGO:0034504550.011
regulation of locomotionGO:0040012420.011
nephron morphogenesisGO:007202830.011
innate immune responseGO:00450871440.011
single organism cell adhesionGO:0098602470.011
meiosis iGO:0007127590.011
asymmetric stem cell divisionGO:0098722490.011
nucleobase containing compound catabolic processGO:00346551650.011
cellular component assembly involved in morphogenesisGO:00109271510.011
purine nucleoside triphosphate metabolic processGO:00091441190.011
positive regulation of immune system processGO:0002684680.011
determination of adult lifespanGO:00083401370.011
anterior posterior axis specification embryoGO:00085951030.011
regulation of cyclin dependent protein serine threonine kinase activityGO:000007930.011
camera type eye morphogenesisGO:004859320.011
stress activated protein kinase signaling cascadeGO:0031098550.011
open tracheal system developmentGO:00074242040.011
response to radiationGO:00093141550.011
neuroblast proliferationGO:0007405740.011
connective tissue developmentGO:006144830.011
cell agingGO:000756920.011
macromolecular complex assemblyGO:00650032560.011
chromosome condensationGO:0030261410.011
nuclear transportGO:0051169720.011
negative regulation of cellular biosynthetic processGO:00313272770.011
larval developmentGO:00021641040.011
multi organism reproductive behaviorGO:00447051210.011
regulation of antimicrobial peptide productionGO:0002784440.011
chromosome segregationGO:00070591570.011
eggshell formationGO:00307031050.011
dna dependent dna replicationGO:0006261170.011
peptidyl lysine modificationGO:0018205570.011
axon target recognitionGO:0007412160.011
mesenchymal cell developmentGO:001403110.010
regulation of transferase activityGO:0051338580.010
regulation of protein secretionGO:0050708130.010
cellular macromolecular complex assemblyGO:00346221530.010
regulation of protein polymerizationGO:0032271280.010
positive regulation of protein metabolic processGO:00512471280.010
female germ line stem cell asymmetric divisionGO:0048132140.010
urogenital system developmentGO:0001655720.010
regulation of epithelial cell differentiationGO:003085640.010
glial cell differentiationGO:0010001350.010
immune response regulating signaling pathwayGO:000276420.010
regulation of protein modification processGO:00313991120.010
nucleobase containing small molecule metabolic processGO:00550861740.010
tripartite regional subdivisionGO:00073511030.010
positive regulation of immune responseGO:0050778630.010
compound eye morphogenesisGO:00017452490.010
response to lipidGO:0033993380.010
positive regulation of phosphorus metabolic processGO:00105621390.010
negative regulation of chromosome segregationGO:0051985140.010
microtubule polymerization or depolymerizationGO:0031109390.010

brn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.036
organ system cancerDOID:005068600.013
cancerDOID:16200.013
disease of cellular proliferationDOID:1456600.013
musculoskeletal system diseaseDOID:1700.012
bone diseaseDOID:008000100.012
bone development diseaseDOID:008000600.012
connective tissue diseaseDOID:6500.012