Drosophila melanogaster

4 known processes

plx (Dmel_CG42612)

pollux

(Aliases: Dmel_CG14674,CG42612,Dmel\CG42612,CG14674,Dmel_CG1093,Dmel_CG34122,CG34122,CG1093)

plx biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
larval behaviorGO:0030537420.928
single organism behaviorGO:00447083910.924
response to abiotic stimulusGO:00096283410.878
respiratory system developmentGO:00605412130.766
mechanosensory behaviorGO:0007638120.751
neurological system processGO:00508773580.672
sensory perception of salty tasteGO:005091430.616
inorganic cation transmembrane transportGO:0098662610.522
detection of mechanical stimulus involved in sensory perception of painGO:005096620.520
salt aversionGO:003519930.482
detection of stimulusGO:00516061560.471
sensory perception of mechanical stimulusGO:0050954720.441
male courtship behaviorGO:0008049630.418
open tracheal system developmentGO:00074242040.405
response to mechanical stimulusGO:0009612280.378
cellular response to abiotic stimulusGO:0071214580.349
inter male aggressive behaviorGO:0002121600.347
courtship behaviorGO:0007619680.323
epibolyGO:009050420.288
sensory perceptionGO:00076001960.280
homeostatic processGO:00425921990.280
ion transmembrane transportGO:00342201220.270
metal ion homeostasisGO:0055065440.250
matingGO:00076181200.240
transmembrane transportGO:00550851390.221
sensory perception of touchGO:0050975110.211
response to light stimulusGO:00094161240.211
cation transmembrane transportGO:0098655880.209
cation homeostasisGO:0055080510.202
locomotory behaviorGO:00076261760.198
response to radiationGO:00093141550.179
multi multicellular organism processGO:00447061230.175
synaptic transmissionGO:00072682880.172
response to decreased oxygen levelsGO:0036293580.156
male mating behaviorGO:0060179700.148
sensory perception of painGO:001923340.146
metal ion transportGO:0030001740.141
chemical homeostasisGO:0048878920.133
localization of cellGO:00516742570.131
cellular response to water stimulusGO:007146220.128
behavioral response to painGO:004826630.127
feeding behaviorGO:0007631500.125
multi organism behaviorGO:00517051750.122
water homeostasisGO:003010430.121
aggressive behaviorGO:0002118630.116
ion transportGO:00068111450.116
response to painGO:004826530.115
reproductive behaviorGO:00190981220.112
morphogenesis of an epitheliumGO:00020092760.110
epiboly involved in wound healingGO:009050520.109
larval locomotory behaviorGO:0008345270.108
tissue morphogenesisGO:00487292970.106
response to hypoxiaGO:0001666530.105
response to inorganic substanceGO:0010035440.102
regulation of ion transportGO:0043269390.094
cognitionGO:00508901410.093
detection of stimulus involved in sensory perceptionGO:0050906920.091
fluid transportGO:0042044190.090
ion homeostasisGO:0050801550.088
negative regulation of response to stimulusGO:00485852580.088
response to temperature stimulusGO:00092661060.087
cellular response to mechanical stimulusGO:007126020.082
cell migrationGO:00164772380.082
rhythmic processGO:00485111060.079
central nervous system developmentGO:00074172010.078
response to salt stressGO:0009651110.076
taxisGO:00423303040.073
response to oxygen levelsGO:0070482590.073
nuclear divisionGO:00002803320.072
cellular response to organic substanceGO:00713101320.071
branching involved in open tracheal system developmentGO:0060446450.070
regulation of synaptic transmissionGO:0050804690.069
regulation of membrane potentialGO:0042391350.068
trachea morphogenesisGO:0060439220.068
inorganic ion transmembrane transportGO:0098660730.068
sodium ion transportGO:0006814220.068
sensory perception of chemical stimulusGO:00076061160.067
detection of abiotic stimulusGO:0009582660.066
cellular response to chemical stimulusGO:00708871990.062
terminal branching open tracheal systemGO:0007430170.062
response to organic substanceGO:00100332840.059
regulation of response to stressGO:00801342000.059
regulation of behaviorGO:0050795750.058
forebrain developmentGO:003090020.058
small molecule metabolic processGO:00442813050.055
trachea developmentGO:0060438290.054
response to pheromoneGO:0019236190.053
wound healing spreading of epidermal cellsGO:003531310.053
regulation of cellular localizationGO:00603411360.051
camera type eye developmentGO:004301040.049
negative regulation of cellular metabolic processGO:00313243820.049
learning or memoryGO:00076111410.048
brain developmentGO:00074201200.048
establishment of localization in cellGO:00516494020.048
regulation of localizationGO:00328792750.048
multicellular organismal agingGO:00102591400.047
organic substance transportGO:00717022570.045
cation transportGO:00068121100.045
cellular response to nitrogen compoundGO:1901699510.044
response to organophosphorusGO:004668320.043
determination of adult lifespanGO:00083401370.043
response to monosaccharideGO:003428440.041
circulatory system processGO:0003013370.041
mating behaviorGO:00076171060.041
response to oxygen containing compoundGO:19017002000.040
negative regulation of cell communicationGO:00106482230.040
muscle system processGO:0003012210.040
phosphorylationGO:00163102940.040
monovalent inorganic cation transportGO:0015672400.039
sensory perception of tasteGO:0050909250.038
defense responseGO:00069523000.038
response to glucoseGO:000974920.038
drinking behaviorGO:004275620.037
epithelial cell migration open tracheal systemGO:0007427320.037
response to organic cyclic compoundGO:0014070890.037
cellular amino acid metabolic processGO:0006520610.037
regulation of transportGO:00510491810.037
catabolic processGO:00090564090.037
negative regulation of nitrogen compound metabolic processGO:00511722650.036
intracellular signal transductionGO:00355563000.036
cellular response to oxygen containing compoundGO:1901701790.036
spermatogenesisGO:00072832000.035
organelle fissionGO:00482853400.035
regulation of molecular functionGO:00650092170.035
regulation of catalytic activityGO:00507901850.034
dendrite developmentGO:00163582040.034
enzyme linked receptor protein signaling pathwayGO:00071671790.033
wound healing spreading of cellsGO:004431920.033
cranial nerve developmentGO:002154510.032
mitotic nuclear divisionGO:00070672130.032
learningGO:0007612750.032
positive regulation of cell communicationGO:00106472500.032
regulation of synapse structure and activityGO:00508031280.032
male gamete generationGO:00482322010.031
multi organism reproductive behaviorGO:00447051210.031
nitrogen compound transportGO:0071705850.031
circadian rhythmGO:00076231050.031
response to external biotic stimulusGO:00432072930.031
single organism biosynthetic processGO:00447112060.030
protein localizationGO:00081042840.030
regulation of phosphorus metabolic processGO:00511742100.029
positive regulation of molecular functionGO:00440931360.029
regulation of multicellular organismal developmentGO:20000264140.029
eye developmentGO:00016543230.029
regulation of tube architecture open tracheal systemGO:0035152680.029
macromolecule catabolic processGO:00090571610.028
cell divisionGO:00513012480.027
carbohydrate derivative metabolic processGO:19011352170.027
regulation of cell differentiationGO:00455953020.027
regulation of protein metabolic processGO:00512462560.027
positive regulation of response to stimulusGO:00485843230.027
agingGO:00075681430.027
response to nitrogen compoundGO:1901698900.027
regulation of cellular catabolic processGO:00313291570.027
negative regulation of signalingGO:00230572190.027
organic cyclic compound catabolic processGO:19013611680.027
body morphogenesisGO:001017120.026
response to alcoholGO:0097305950.026
detection of external stimulusGO:0009581660.026
positive regulation of signal transductionGO:00099672230.026
multicellular organismal reproductive behaviorGO:00330571100.026
single organism carbohydrate metabolic processGO:0044723720.025
heterocycle catabolic processGO:00467001660.025
regulation of cell cycleGO:00517262910.025
potassium ion transportGO:0006813200.025
positive regulation of signalingGO:00230562430.025
kidney developmentGO:000182230.025
blood circulationGO:0008015260.024
immune system processGO:00023763470.024
regulation of cellular ketone metabolic processGO:001056530.024
cellular homeostasisGO:0019725800.024
phagocytosisGO:00069092150.024
rhythmic behaviorGO:0007622760.024
regulation of hydrolase activityGO:0051336970.024
mapk cascadeGO:00001651070.024
peptidyl amino acid modificationGO:00181931050.023
memoryGO:0007613940.023
response to woundingGO:0009611940.023
response to bacteriumGO:00096171980.023
regulation of cellular amino acid metabolic processGO:000652100.023
organic substance catabolic processGO:19015753080.023
response to endogenous stimulusGO:00097191190.023
cellular response to carbohydrate stimulusGO:007132240.023
oxoacid metabolic processGO:00434361030.022
regulation of response to nutrient levelsGO:0032107180.022
transcription from rna polymerase ii promoterGO:00063663680.022
response to organonitrogen compoundGO:0010243750.022
protein maturationGO:0051604710.022
vesicle mediated transportGO:00161923810.022
tube morphogenesisGO:00352391910.022
regulation of system processGO:0044057360.022
regulation of feeding behaviorGO:0060259160.022
regulation of synaptic activityGO:006002590.021
cell deathGO:00082192790.021
carboxylic acid metabolic processGO:0019752920.021
gliogenesisGO:0042063800.021
cell cell junction assemblyGO:0007043380.021
negative regulation of signal transductionGO:00099682060.021
meiotic cell cycleGO:00513211710.021
protein complex assemblyGO:00064612000.020
cellular response to external stimulusGO:0071496660.020
action potentialGO:0001508130.020
somatic muscle developmentGO:0007525660.020
intracellular transportGO:00469072280.020
connective tissue developmentGO:006144830.020
olfactory behaviorGO:0042048970.020
endomembrane system organizationGO:00102561190.020
aromatic compound catabolic processGO:00194391660.020
nucleocytoplasmic transportGO:0006913720.020
heart processGO:0003015370.019
positive regulation of nitrogen compound metabolic processGO:00511733540.019
regulation of intracellular signal transductionGO:19025312360.019
cell motilityGO:00488702510.019
gravitaxisGO:0042332260.019
membrane depolarizationGO:005189940.019
purine ribonucleoside metabolic processGO:00461281270.019
nucleobase containing small molecule metabolic processGO:00550861740.019
branching morphogenesis of an epithelial tubeGO:0048754450.019
single organism intracellular transportGO:19025822070.019
purine nucleoside triphosphate catabolic processGO:00091461080.019
deathGO:00162652840.019
developmental programmed cell deathGO:00106231380.019
intracellular protein transportGO:00068861040.019
ribonucleoside catabolic processGO:00424541120.018
immune responseGO:00069552460.018
cellular component assembly involved in morphogenesisGO:00109271510.018
embryo development ending in birth or egg hatchingGO:00097921520.018
negative regulation of transcription dna templatedGO:00458922370.018
cuticle developmentGO:0042335860.018
salivary gland morphogenesisGO:00074351450.018
innate immune responseGO:00450871440.018
regulation of phosphate metabolic processGO:00192202100.018
negative regulation of cell cycleGO:00457861160.017
regulation of anatomical structure sizeGO:00900661630.017
ribonucleotide metabolic processGO:00092591450.017
response to other organismGO:00517072930.017
response to acid chemicalGO:0001101250.017
cellular protein modification processGO:00064644380.017
morphogenesis of a branching structureGO:0001763450.017
organonitrogen compound metabolic processGO:19015643180.017
gene silencingGO:00164581380.017
negative regulation of cell cycle phase transitionGO:19019881030.017
positive regulation of macromolecule metabolic processGO:00106044050.017
secretion by cellGO:00329401010.017
protein complex biogenesisGO:00702712010.017
response to hexoseGO:000974630.017
heart contractionGO:0060047260.017
chemosensory behaviorGO:00076351060.017
cellular catabolic processGO:00442483720.017
multicellular organismal response to stressGO:003355550.017
signal transduction by phosphorylationGO:00230141070.017
organic acid metabolic processGO:00060821030.017
cellular response to organonitrogen compoundGO:0071417360.017
regulation of cellular response to stressGO:0080135890.017
spindle organizationGO:00070512530.017
tissue deathGO:00162711020.017
macromolecular complex assemblyGO:00650032560.016
regulation of cell cycle processGO:00105641810.016
embryonic morphogenesisGO:00485982060.016
nucleobase containing compound catabolic processGO:00346551650.016
regulation of purine nucleotide catabolic processGO:0033121480.016
cellular macromolecule catabolic processGO:00442651360.016
stem cell divisionGO:0017145690.016
negative regulation of cellular component organizationGO:00511291080.016
single organismal cell cell adhesionGO:0016337450.016
nucleoside phosphate metabolic processGO:00067531620.016
regulation of epithelial cell migration open tracheal systemGO:2000274110.016
l amino acid importGO:004309220.016
single organism catabolic processGO:00447122280.016
morphogenesis of a branching epitheliumGO:0061138450.016
striated muscle cell developmentGO:0055002500.016
regulation of metal ion transportGO:0010959150.016
synapse organizationGO:00508081960.016
nucleotide metabolic processGO:00091171610.015
cell maturationGO:00484691440.015
response to purine containing compoundGO:0014074120.015
cellular response to endogenous stimulusGO:0071495800.015
ribonucleotide catabolic processGO:00092611090.015
response to biotic stimulusGO:00096072940.015
organelle assemblyGO:00709251980.015
detection of mechanical stimulusGO:005098260.015
negative regulation of cell cycle processGO:00109481090.015
cellular response to dna damage stimulusGO:00069742230.015
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.015
protein modification processGO:00362114380.015
regulation of catabolic processGO:00098941700.015
regulation of cellular protein metabolic processGO:00322682430.015
wound healingGO:0042060750.015
nucleoside metabolic processGO:00091161270.015
cellular response to hexose stimulusGO:007133110.015
cellular nitrogen compound catabolic processGO:00442701650.015
imaginal disc derived appendage morphogenesisGO:00351143950.015
nuclear transportGO:0051169720.015
regulation of cellular amine metabolic processGO:003323830.015
cellular macromolecule localizationGO:00707272200.014
small gtpase mediated signal transductionGO:0007264880.014
ribonucleoside triphosphate metabolic processGO:00091991190.014
gland developmentGO:00487321910.014
response to nutrient levelsGO:00316671140.014
regulation of immune system processGO:00026821760.014
cellular modified amino acid metabolic processGO:0006575450.014
neuromuscular synaptic transmissionGO:0007274670.014
negative regulation of mitotic cell cycleGO:00459301090.014
dna endoreduplicationGO:0042023220.014
proteolysisGO:00065081920.014
regulation of ion transmembrane transportGO:0034765270.014
positive regulation of catalytic activityGO:00430851180.014
positive regulation of epithelial cell differentiationGO:003085810.014
muscle contractionGO:0006936130.014
regulation of excitatory postsynaptic membrane potentialGO:006007930.014
regulation of proteolysisGO:0030162870.014
autophagic cell deathGO:0048102830.014
glycosyl compound metabolic processGO:19016571270.014
maintenance of epithelial integrity open tracheal systemGO:0035160120.014
negative regulation of gene expressionGO:00106293870.014
microtubule polymerization or depolymerizationGO:0031109390.014
carbohydrate homeostasisGO:0033500120.014
cellular protein localizationGO:00346131600.014
regulation of wnt signaling pathwayGO:0030111680.014
ribonucleoside metabolic processGO:00091191270.014
response to extracellular stimulusGO:00099911160.014
head developmentGO:00603221350.014
protein phosphorylationGO:00064681690.014
liquid clearance open tracheal systemGO:0035002130.014
regulation of defense responseGO:00313471020.014
glial cell developmentGO:0021782270.014
epithelial tube morphogenesisGO:0060562880.014
cellular protein catabolic processGO:0044257830.013
epithelial fluid transportGO:0042045170.013
anatomical structure homeostasisGO:0060249970.013
positive regulation of transcription dna templatedGO:00458932660.013
purine nucleoside metabolic processGO:00422781270.013
purine nucleoside catabolic processGO:00061521120.013
thermosensory behaviorGO:0040040190.013
glycosyl compound catabolic processGO:19016581120.013
purine containing compound metabolic processGO:00725211550.013
multicellular organismal signalingGO:0035637120.013
organophosphate catabolic processGO:00464341120.013
salivary gland developmentGO:00074311620.013
protein transportGO:00150311550.013
regulation of body fluid levelsGO:0050878140.013
wing disc morphogenesisGO:00074723440.013
regulation of muscle contractionGO:000693750.013
negative regulation of multicellular organismal processGO:00512411420.013
defense response to bacteriumGO:00427421780.012
segmentationGO:00352822070.012
regulation of nucleotide metabolic processGO:0006140620.012
negative regulation of mitotic cell cycle phase transitionGO:19019911030.012
cellular response to monosaccharide stimulusGO:007132620.012
regulation of cellular component biogenesisGO:00440872010.012
cellular protein complex assemblyGO:0043623710.012
g2 dna damage checkpointGO:0031572690.012
positive regulation of cellular amine metabolic processGO:003324000.012
protein catabolic processGO:00301631010.012
microtubule cytoskeleton organization involved in mitosisGO:1902850520.012
imaginal disc derived wing morphogenesisGO:00074763370.012
columnar cuboidal epithelial cell differentiationGO:00020652560.012
protein modification by small protein conjugation or removalGO:00706471060.012
negative regulation of nucleobase containing compound metabolic processGO:00459342610.012
cellular response to acid chemicalGO:007122980.012
organ growthGO:0035265560.012
purine ribonucleoside catabolic processGO:00461301120.012
negative regulation of rna biosynthetic processGO:19026792400.012
divalent metal ion transportGO:0070838260.012
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.012
programmed cell deathGO:00125012570.012
ribonucleoside triphosphate catabolic processGO:00092031080.012
negative regulation of biosynthetic processGO:00098902770.012
developmental maturationGO:00217001720.012
oocyte maturationGO:000155630.012
cellular chemical homeostasisGO:0055082400.012
sulfur compound metabolic processGO:0006790590.011
regulation of heart contractionGO:0008016210.011
specification of organ identityGO:001009230.011
hindbrain developmentGO:003090220.011
negative regulation of macromolecule biosynthetic processGO:00105582700.011
meiotic nuclear divisionGO:00071261510.011
positive regulation of phosphorus metabolic processGO:00105621390.011
cellular response to organic cyclic compoundGO:0071407320.011
nucleoside triphosphate metabolic processGO:00091411200.011
chitin based cuticle developmentGO:0040003490.011
dna integrity checkpointGO:0031570810.011
syncytium formation by plasma membrane fusionGO:0000768430.011
nucleoside catabolic processGO:00091641120.011
adult behaviorGO:00305341370.011
positive regulation of cellular biosynthetic processGO:00313283160.011
mitotic spindle organizationGO:00070522200.011
purine nucleoside triphosphate metabolic processGO:00091441190.011
carbohydrate metabolic processGO:0005975820.011
biological adhesionGO:00226101380.011
cellular ketone metabolic processGO:0042180240.011
guanosine containing compound metabolic processGO:1901068740.011
response to carbohydrateGO:0009743150.011
cellular amine metabolic processGO:0044106120.011
glandular epithelial cell differentiationGO:000206710.011
establishment of protein localizationGO:00451841630.011
defense response to other organismGO:00985422250.011
purine containing compound catabolic processGO:00725231120.011
negative regulation of cellular protein metabolic processGO:0032269850.011
regulation of mitotic cell cycleGO:00073461900.011
positive regulation of peptidase activityGO:0010952290.011
amine metabolic processGO:0009308120.010
regulation of establishment of protein localizationGO:0070201610.010
imaginal disc derived appendage developmentGO:00487373990.010
regionalizationGO:00030024160.010
regulation of protein localizationGO:0032880760.010
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.010
regulation of innate immune responseGO:0045088710.010
organonitrogen compound catabolic processGO:19015651280.010
endocytosisGO:00068973100.010
synapse assemblyGO:00074161430.010
establishment of rna localizationGO:0051236470.010
oocyte differentiationGO:00099941450.010
positive regulation of cellular amino acid metabolic processGO:004576400.010
olfactory learningGO:0008355560.010
negative regulation of phosphate metabolic processGO:0045936450.010
positive regulation of mapk cascadeGO:0043410630.010
mitotic cell cycle phase transitionGO:00447721380.010

plx disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
lower respiratory tract diseaseDOID:005016100.735
disease of anatomical entityDOID:700.735
respiratory system diseaseDOID:157900.735
bronchial diseaseDOID:117600.735
renal tubular transport diseaseDOID:44700.568
liddle syndromeDOID:005047700.568
kidney diseaseDOID:55700.568
urinary system diseaseDOID:1800.568
bronchiectasisDOID:956300.251
inherited metabolic disorderDOID:65500.034
disease of metabolismDOID:001466700.034
nervous system diseaseDOID:86300.030
glucose metabolism diseaseDOID:419400.028
acquired metabolic diseaseDOID:006015800.028
carbohydrate metabolism diseaseDOID:005001300.028
cardiovascular system diseaseDOID:128700.025
heart conduction diseaseDOID:1027300.025
musculoskeletal system diseaseDOID:1700.020
bone diseaseDOID:008000100.019
connective tissue diseaseDOID:6500.019
eye diseaseDOID:561400.015
sensory system diseaseDOID:005015500.015
eye and adnexa diseaseDOID:149200.015
diabetes mellitusDOID:935100.013
vascular diseaseDOID:17800.012
artery diseaseDOID:005082800.012