Drosophila melanogaster

22 known processes

Hsp70Ab (Dmel_CG18743)

Heat-shock-protein-70Ab

(Aliases: Hsp70A,GRP78,HSP70,Hsp70,Hsp70aB,hsp70(87A),DMHSP7A2,hsp-70,hsp70,Hsp70ab,Hsp 70,CG18743,dhsp70,hsp70a,Hsp70-Ab,Dm-hsp70,hsp70 87A,hsp 70,Dmel\CG18743,dHsp70,hsp70A,hs70,hsp70Ab)

Hsp70Ab biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
heat shock mediated polytene chromosome puffingGO:003508071.000
cellular response to heatGO:0034605240.997
response to heatGO:0009408630.883
determination of adult lifespanGO:00083401370.871
Fly
multicellular organismal agingGO:00102591400.838
Fly
polytene chromosome puffingGO:003507970.823
agingGO:00075681430.808
Fly
response to temperature stimulusGO:00092661060.791
response to starvationGO:0042594970.768
Fly
chromosome organizationGO:00512763600.734
response to organic substanceGO:00100332840.698
Fly
response to oxygen containing compoundGO:19017002000.577
Fly
response to abiotic stimulusGO:00096283410.556
response to nitrogen compoundGO:1901698900.538
Fly
response to nutrient levelsGO:00316671140.528
Fly
response to organic cyclic compoundGO:0014070890.469
Fly
response to organonitrogen compoundGO:0010243750.436
Fly
response to hypoxiaGO:0001666530.356
response to decreased oxygen levelsGO:0036293580.311
response to endogenous stimulusGO:00097191190.232
Fly
response to acid chemicalGO:0001101250.215
Fly
response to methotrexateGO:0031427110.095
Fly
response to oxygen levelsGO:0070482590.095
response to extracellular stimulusGO:00099911160.075
Fly
taxisGO:00423303040.060
appendage developmentGO:00487364010.058
wound healingGO:0042060750.056
lateral inhibitionGO:00463312060.055
defense response to bacteriumGO:00427421780.054
negative regulation of cellular metabolic processGO:00313243820.052
neurological system processGO:00508773580.051
body morphogenesisGO:001017120.050
deathGO:00162652840.046
regulation of growthGO:00400082330.043
appendage morphogenesisGO:00351073970.041
apoptotic processGO:00069151590.038
ameboidal type cell migrationGO:00016671510.037
programmed cell deathGO:00125012570.036
wing disc morphogenesisGO:00074723440.036
single organism behaviorGO:00447083910.035
epithelial cell migrationGO:00106311480.035
negative regulation of cellular biosynthetic processGO:00313272770.034
cellular amino acid metabolic processGO:0006520610.034
imaginal disc derived appendage morphogenesisGO:00351143950.033
response to other organismGO:00517072930.033
imaginal disc derived wing morphogenesisGO:00074763370.033
negative regulation of gene expressionGO:00106293870.033
response to external biotic stimulusGO:00432072930.033
negative regulation of biosynthetic processGO:00098902770.033
regulation of cellular ketone metabolic processGO:001056530.033
sensory organ morphogenesisGO:00905962600.032
defense response to other organismGO:00985422250.032
regulation of cellular component biogenesisGO:00440872010.031
regulation of transcription from rna polymerase ii promoterGO:00063573780.031
response to biotic stimulusGO:00096072940.030
tissue deathGO:00162711020.030
locomotory behaviorGO:00076261760.029
catabolic processGO:00090564090.029
cell motilityGO:00488702510.029
vesicle mediated transportGO:00161923810.029
cognitionGO:00508901410.029
negative regulation of reactive oxygen species metabolic processGO:200037810.028
cell cell signaling involved in cell fate commitmentGO:00451682100.028
organonitrogen compound metabolic processGO:19015643180.028
oxoacid metabolic processGO:00434361030.027
cellular response to chemical stimulusGO:00708871990.027
cellular protein catabolic processGO:0044257830.027
defense responseGO:00069523000.026
post embryonic appendage morphogenesisGO:00351203850.026
cellular amine metabolic processGO:0044106120.026
positive regulation of nucleobase containing compound metabolic processGO:00459353320.025
endocytosisGO:00068973100.024
synapse organizationGO:00508081960.024
response to oxidative stressGO:0006979860.024
positive regulation of cell migrationGO:003033520.023
regulation of phosphorus metabolic processGO:00511742100.023
carboxylic acid metabolic processGO:0019752920.023
humoral immune responseGO:00069591170.023
cellular ketone metabolic processGO:0042180240.023
response to woundingGO:0009611940.022
phagocytosisGO:00069092150.022
transcription from rna polymerase ii promoterGO:00063663680.022
regulation of cellular amino acid metabolic processGO:000652100.022
homeostatic processGO:00425921990.022
imaginal disc derived appendage developmentGO:00487373990.021
epithelial cell developmentGO:00020642740.021
ribonucleoside triphosphate metabolic processGO:00091991190.021
positive regulation of cellular biosynthetic processGO:00313283160.021
cell divisionGO:00513012480.021
learning or memoryGO:00076111410.021
regulation of epithelial cell proliferationGO:005067840.021
organophosphate metabolic processGO:00196371950.021
epithelial cell differentiationGO:00308553220.020
regulation of cellular protein metabolic processGO:00322682430.020
epithelium migrationGO:00901321480.020
regulation of cellular amine metabolic processGO:003323830.020
eye morphogenesisGO:00485922600.020
response to lipopolysaccharideGO:003249640.020
cellular protein modification processGO:00064644380.020
negative regulation of rna metabolic processGO:00512532510.020
salivary gland developmentGO:00074311620.020
proteolysis involved in cellular protein catabolic processGO:0051603830.020
signal transduction by phosphorylationGO:00230141070.019
neuromuscular junction developmentGO:00075281490.019
small molecule metabolic processGO:00442813050.019
cellular catabolic processGO:00442483720.019
cellular response to ionizing radiationGO:0071479150.019
forebrain developmentGO:003090020.019
salivary gland morphogenesisGO:00074351450.019
organic substance catabolic processGO:19015753080.019
positive regulation of cell communicationGO:00106472500.019
proteolysisGO:00065081920.019
camera type eye developmentGO:004301040.019
regulation of cellular catabolic processGO:00313291570.019
gland developmentGO:00487321910.019
cell migrationGO:00164772380.019
regulation of anatomical structure morphogenesisGO:00226032420.019
connective tissue developmentGO:006144830.019
small gtpase mediated signal transductionGO:0007264880.019
regulation of molecular functionGO:00650092170.019
establishment of localization in cellGO:00516494020.019
limb developmentGO:006017310.018
negative regulation of nucleobase containing compound metabolic processGO:00459342610.018
compound eye developmentGO:00487493070.018
single organismal cell cell adhesionGO:0016337450.018
negative regulation of nitrogen compound metabolic processGO:00511722650.018
positive regulation of nucleic acid templated transcriptionGO:19035082660.018
localization of cellGO:00516742570.018
histolysisGO:00075591020.017
cell adhesionGO:00071551360.017
regulation of cell cycleGO:00517262910.017
response to radiationGO:00093141550.017
camera type eye morphogenesisGO:004859320.017
respiratory system developmentGO:00605412130.017
amine metabolic processGO:0009308120.017
actin filament organizationGO:00070151260.017
actin cytoskeleton organizationGO:00300362060.017
intracellular transportGO:00469072280.017
male gamete generationGO:00482322010.017
purine ribonucleotide catabolic processGO:00091541090.017
response to organophosphorusGO:004668320.017
positive regulation of cellular component organizationGO:00511301560.016
cellular macromolecule catabolic processGO:00442651360.016
purine nucleotide metabolic processGO:00061631460.016
positive regulation of cellular catabolic processGO:0031331950.016
spermatogenesisGO:00072832000.016
purine nucleoside triphosphate metabolic processGO:00091441190.016
negative regulation of response to stimulusGO:00485852580.016
modification dependent protein catabolic processGO:0019941780.016
negative regulation of macromolecule biosynthetic processGO:00105582700.016
nuclear divisionGO:00002803320.016
regulation of mitotic cell cycle phase transitionGO:19019901300.016
dorsal ventral pattern formationGO:00099531330.016
proteasomal protein catabolic processGO:0010498590.016
regulation of localizationGO:00328792750.016
response to light stimulusGO:00094161240.016
autophagyGO:00069141080.016
regionalizationGO:00030024160.016
organic substance transportGO:00717022570.016
single organism biosynthetic processGO:00447112060.015
purine ribonucleoside catabolic processGO:00461301120.015
polyol biosynthetic processGO:004617330.015
cell deathGO:00082192790.015
regulation of catabolic processGO:00098941700.015
developmental growthGO:00485892800.015
immune responseGO:00069552460.015
positive regulation of signalingGO:00230562430.015
ribonucleotide metabolic processGO:00092591450.015
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.015
macromolecule catabolic processGO:00090571610.015
exocrine system developmentGO:00352721620.015
carbohydrate derivative metabolic processGO:19011352170.015
notch signaling pathwayGO:00072191200.015
ribose phosphate metabolic processGO:00196931450.015
chemotaxisGO:00069352490.015
xenobiotic catabolic processGO:004217810.015
developmental programmed cell deathGO:00106231380.015
tissue morphogenesisGO:00487292970.015
gland morphogenesisGO:00226121450.015
protein localizationGO:00081042840.015
hindbrain developmentGO:003090220.015
positive regulation of nitrogen compound metabolic processGO:00511733540.015
positive regulation of cell motilityGO:200014730.015
positive regulation of cellular amine metabolic processGO:003324000.015
negative regulation of rna biosynthetic processGO:19026792400.015
glycosyl compound metabolic processGO:19016571270.015
growthGO:00400073590.015
regulation of tube sizeGO:0035150460.015
cell proliferationGO:00082832990.015
embryonic morphogenesisGO:00485982060.014
sterol homeostasisGO:005509240.014
salivary gland histolysisGO:0035070880.014
regulation of multicellular organismal developmentGO:20000264140.014
tissue migrationGO:00901301550.014
cellular nitrogen compound catabolic processGO:00442701650.014
fat soluble vitamin biosynthetic processGO:004236210.014
ras protein signal transductionGO:0007265880.014
antimicrobial humoral responseGO:0019730990.014
cellular response to molecule of bacterial originGO:007121930.014
macromolecular complex assemblyGO:00650032560.014
purine ribonucleotide metabolic processGO:00091501450.014
protein catabolic processGO:00301631010.014
synapse assemblyGO:00074161430.014
regulation of transportGO:00510491810.014
regulation of cell cycle phase transitionGO:19019871300.014
nucleoside phosphate catabolic processGO:19012921100.014
olfactory behaviorGO:0042048970.014
negative regulation of nucleic acid templated transcriptionGO:19035072400.014
positive regulation of signal transductionGO:00099672230.014
positive regulation of macromolecule metabolic processGO:00106044050.014
salivary gland cell autophagic cell deathGO:0035071830.014
chemosensory behaviorGO:00076351060.014
purine ribonucleoside triphosphate catabolic processGO:00092071080.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.014
positive regulation of phosphorus metabolic processGO:00105621390.014
neuron projection guidanceGO:00974852410.014
positive regulation of nucleotide metabolic processGO:0045981550.013
meiosis iGO:0007127590.013
positive regulation of catabolic processGO:00098961050.013
muscle organ developmentGO:00075171270.013
regulation of notch signaling pathwayGO:00085931000.013
learningGO:0007612750.013
limb morphogenesisGO:003510810.013
regulation of mitotic cell cycleGO:00073461900.013
cellular response to oxygen containing compoundGO:1901701790.013
posttranscriptional regulation of gene expressionGO:00106081450.013
intracellular signal transductionGO:00355563000.013
regulation of cell cycle processGO:00105641810.013
small molecule biosynthetic processGO:0044283370.013
regulation of catalytic activityGO:00507901850.013
negative regulation of cellular component organizationGO:00511291080.013
aromatic compound catabolic processGO:00194391660.013
sensory perception of chemical stimulusGO:00076061160.013
morphogenesis of an epitheliumGO:00020092760.013
regulation of cell differentiationGO:00455953020.013
nucleobase containing small molecule metabolic processGO:00550861740.013
positive regulation of apoptotic signaling pathwayGO:200123540.013
negative regulation of transcription dna templatedGO:00458922370.013
peptidyl lysine modificationGO:0018205570.013
negative regulation of signal transductionGO:00099682060.013
response to glucoseGO:000974920.013
microtubule organizing center organizationGO:00310231680.013
enzyme linked receptor protein signaling pathwayGO:00071671790.012
meiotic cell cycleGO:00513211710.012
molting cycle chitin based cuticleGO:0007591560.012
single organism catabolic processGO:00447122280.012
nucleobase containing compound catabolic processGO:00346551650.012
rrna processingGO:000636430.012
phosphorylationGO:00163102940.012
positive regulation of cellular protein metabolic processGO:00322701180.012
actin filament based processGO:00300292200.012
nucleoside catabolic processGO:00091641120.012
matingGO:00076181200.012
immune system processGO:00023763470.012
organelle assemblyGO:00709251980.012
regulation of rna splicingGO:0043484690.012
regulation of organelle organizationGO:00330431960.012
regulation of anatomical structure sizeGO:00900661630.012
extrinsic apoptotic signaling pathwayGO:009719110.012
biological adhesionGO:00226101380.012
regulation of cell morphogenesisGO:00226041630.012
autophagic cell deathGO:0048102830.012
mesenchymal cell developmentGO:001403110.012
imaginal disc pattern formationGO:0007447910.012
cellular response to abiotic stimulusGO:0071214580.012
compound eye morphogenesisGO:00017452490.012
behavioral response to ethanolGO:0048149490.012
mitotic cell cycle phase transitionGO:00447721380.012
regulation of apoptotic processGO:00429811300.012
mrna processingGO:00063971040.012
positive regulation of rna biosynthetic processGO:19026802660.012
regulation of protein metabolic processGO:00512462560.012
protein complex biogenesisGO:00702712010.012
mesenchymal cell differentiationGO:004876210.012
regulation of response to stressGO:00801342000.012
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.012
purine nucleoside triphosphate catabolic processGO:00091461080.012
positive regulation of transcription dna templatedGO:00458932660.012
ribonucleotide catabolic processGO:00092611090.012
regulation of cell proliferationGO:00421271630.012
chromatin organizationGO:00063252070.012
axis specificationGO:00097981670.011
photoreceptor cell differentiationGO:00465301700.011
purine containing compound metabolic processGO:00725211550.011
kidney developmentGO:000182230.011
positive regulation of cellular amino acid metabolic processGO:004576400.011
regulation of mrna splicing via spliceosomeGO:0048024640.011
regulation of chromosome organizationGO:0033044640.011
multi multicellular organism processGO:00447061230.011
nucleoside phosphate metabolic processGO:00067531620.011
regulation of programmed cell deathGO:00430671520.011
steroid catabolic processGO:000670610.011
larval behaviorGO:0030537420.011
phosphatidylethanolamine metabolic processGO:004633710.011
negative regulation of cell communicationGO:00106482230.011
positive regulation of rna metabolic processGO:00512542710.011
cellular response to organic substanceGO:00713101320.011
organic cyclic compound catabolic processGO:19013611680.011
axon developmentGO:00615642970.011
glycosyl compound catabolic processGO:19016581120.011
protein modification processGO:00362114380.011
regulation of intracellular signal transductionGO:19025312360.011
heterocycle catabolic processGO:00467001660.011
positive regulation of multicellular organismal processGO:00512401430.011
cellular protein localizationGO:00346131600.011
protein modification by small protein conjugationGO:0032446790.011
stem cell differentiationGO:00488631170.011
mrna metabolic processGO:00160711240.011
modification dependent macromolecule catabolic processGO:0043632790.011
cellularizationGO:0007349900.011
nephron epithelium developmentGO:007200930.011
mitotic dna integrity checkpointGO:0044774750.011
protein transmembrane transportGO:007180640.011
cell fate determinationGO:0001709910.011
organelle fissionGO:00482853400.011
organophosphate catabolic processGO:00464341120.011
cellular response to dna damage stimulusGO:00069742230.011
tube morphogenesisGO:00352391910.011
cuticle developmentGO:0042335860.011
tube developmentGO:00352952440.011
positive regulation of intracellular signal transductionGO:19025331160.011
regulation of small gtpase mediated signal transductionGO:0051056930.011
positive regulation of gene expressionGO:00106282900.011
meiotic nuclear divisionGO:00071261510.011
medium chain fatty acid metabolic processGO:005179110.011
nucleoside triphosphate catabolic processGO:00091431080.011
telencephalon developmentGO:002153720.011
lipopolysaccharide mediated signaling pathwayGO:003166310.011
cell cycle phase transitionGO:00447701400.011
sensory perceptionGO:00076001960.011
anterior posterior pattern specificationGO:00099521360.010
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.010
organic acid metabolic processGO:00060821030.010
male meiosisGO:0007140520.010
organonitrogen compound catabolic processGO:19015651280.010
regulation of response to external stimulusGO:00321011150.010
muscle structure developmentGO:00610612240.010
regulation of i kappab kinase nf kappab signalingGO:004312220.010
regulation of intracellular transportGO:0032386640.010
cellular protein complex assemblyGO:0043623710.010
spermatid differentiationGO:00485151140.010
response to alcoholGO:0097305950.010
cell projection assemblyGO:0030031940.010
regulation of lipid transportGO:003236830.010
intracellular protein transportGO:00068861040.010
anatomical structure homeostasisGO:0060249970.010
positive regulation of molecular functionGO:00440931360.010
regulation of alternative mrna splicing via spliceosomeGO:0000381600.010
spermatid developmentGO:0007286980.010
positive regulation of catalytic activityGO:00430851180.010
response to monosaccharideGO:003428440.010
negative regulation of growthGO:0045926840.010
regulation of cell growthGO:0001558430.010
positive regulation of biosynthetic processGO:00098913160.010
sensory perception of smellGO:0007608800.010
negative regulation of cellular protein metabolic processGO:0032269850.010
alternative mrna splicing via spliceosomeGO:0000380600.010
regulation of cellular response to stressGO:0080135890.010
single organism intracellular transportGO:19025822070.010

Hsp70Ab disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.065
cardiovascular system diseaseDOID:128700.024
central nervous system diseaseDOID:33100.018
neurodegenerative diseaseDOID:128900.018
nervous system diseaseDOID:86300.018
motor neuron diseaseDOID:23100.018
musculoskeletal system diseaseDOID:1700.016
sensory system diseaseDOID:005015500.015
eye and adnexa diseaseDOID:149200.015
eye diseaseDOID:561400.015
vascular diseaseDOID:17800.013
artery diseaseDOID:005082800.013
neuropathyDOID:87000.012
charcot marie tooth diseaseDOID:1059500.012
charcot marie tooth disease type 2DOID:005053900.012
neuromuscular diseaseDOID:44000.012
cancerDOID:16200.011
disease of cellular proliferationDOID:1456600.011
disease of metabolismDOID:001466700.011
inherited metabolic disorderDOID:65500.011