IMP: Integrative Multi-species Prediction

Drosophila melanogaster

28 known processes

Syx13 (Dmel_CG11278)

Syntaxin 13

(Aliases: Dmel\CG11278,ff16 (69D1-70A2),SYN13,Dm Syx13,CG11278,l(3)01470,ff16,Syx,DmSyx13)

Entrez: 39485
FLYBASE: FBgn0036341
UniProtKB: Q9VU45

Process Predictions
Disease Predictions

Syx13 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
chromosome organization	GO:0051276	360	0.551
meiotic cell cycle process	GO:1903046	132	0.466
ovarian fusome organization	GO:0030723	11	0.356
oocyte nucleus localization involved in oocyte dorsal ventral axis specification	GO:0051663	12	0.293
germarium derived oocyte fate determination	GO:0007294	26	0.281
chromosome segregation	GO:0007059	157	0.252
spindle assembly involved in meiosis	GO:0090306	20	0.248
oocyte differentiation	GO:0009994	145	0.243
spermatocyte division	GO:0048137	13	0.216
establishment of localization in cell	GO:0051649	402	0.216	Fly
dorsal appendage formation	GO:0046843	47	0.213
fusome organization	GO:0045478	13	0.203
female meiotic division	GO:0007143	70	0.194
cellular catabolic process	GO:0044248	372	0.194
growth	GO:0040007	359	0.188	Fly
eggshell formation	GO:0030703	105	0.187
meiotic cell cycle	GO:0051321	171	0.185
cytoplasmic transport nurse cell to oocyte	GO:0007303	12	0.182
nuclear division	GO:0000280	332	0.180
germarium derived egg chamber formation	GO:0007293	101	0.179	Fly
oocyte construction	GO:0007308	112	0.161
regulation of multicellular organismal development	GO:2000026	414	0.160
single organism membrane organization	GO:0044802	93	0.156	Fly
germarium derived oocyte differentiation	GO:0030706	29	0.155
macromolecular complex assembly	GO:0065003	256	0.153
developmental growth	GO:0048589	280	0.152
cell division	GO:0051301	248	0.151
establishment or maintenance of cell polarity	GO:0007163	167	0.151	Fly
pronuclear migration	GO:0035046	4	0.140
oocyte fate determination	GO:0030716	27	0.139
organelle fusion	GO:0048284	46	0.139	Fly
protein modification by small protein conjugation or removal	GO:0070647	106	0.135
male meiosis	GO:0007140	52	0.127
protein complex biogenesis	GO:0070271	201	0.110
cytoskeleton dependent cytokinesis	GO:0061640	81	0.097
macromolecule catabolic process	GO:0009057	161	0.096
oocyte microtubule cytoskeleton organization	GO:0016325	35	0.094
meiotic cytokinesis	GO:0033206	33	0.094
response to nutrient levels	GO:0031667	114	0.094
organelle fission	GO:0048285	340	0.090
neuromuscular junction development	GO:0007528	149	0.087
embryonic pattern specification	GO:0009880	174	0.081
cystoblast division	GO:0007282	10	0.076
organic substance catabolic process	GO:1901575	308	0.074
eggshell chorion assembly	GO:0007306	66	0.074
blastoderm segmentation	GO:0007350	159	0.073
single organism cellular localization	GO:1902580	180	0.071
regionalization	GO:0003002	416	0.070
vesicle mediated transport	GO:0016192	381	0.068	Fly
exocytosis	GO:0006887	28	0.068
single organism intracellular transport	GO:1902582	207	0.068	Fly
chorion containing eggshell formation	GO:0007304	105	0.064
embryo development ending in birth or egg hatching	GO:0009792	152	0.062
catabolic process	GO:0009056	409	0.062
cellular macromolecular complex assembly	GO:0034622	153	0.061
body morphogenesis	GO:0010171	2	0.061
response to organic substance	GO:0010033	284	0.060
chromosome condensation	GO:0030261	41	0.059
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.059
cellular macromolecule localization	GO:0070727	220	0.058
cortical actin cytoskeleton organization	GO:0030866	24	0.056
single organism behavior	GO:0044708	391	0.056
establishment of oocyte nucleus localization involved in oocyte dorsal ventral axis specification	GO:0030722	6	0.055
protein modification process	GO:0036211	438	0.055
epithelial cell differentiation	GO:0030855	322	0.054
establishment of spindle localization	GO:0051293	22	0.054
meiotic nuclear division	GO:0007126	151	0.052
meiotic sister chromatid segregation	GO:0045144	6	0.052
regulation of nervous system development	GO:0051960	248	0.051
meiotic spindle organization	GO:0000212	36	0.050
developmental maturation	GO:0021700	172	0.050
mitotic cell cycle embryonic	GO:0045448	38	0.049
epithelial cell development	GO:0002064	274	0.049
regulation of developmental growth	GO:0048638	174	0.047
organelle localization	GO:0051640	148	0.047
mitotic cell cycle phase transition	GO:0044772	138	0.046
positive regulation of developmental process	GO:0051094	143	0.045
salivary gland morphogenesis	GO:0007435	145	0.044
cellular response to starvation	GO:0009267	61	0.044
dna packaging	GO:0006323	91	0.042
neurological system process	GO:0050877	358	0.042
synaptic growth at neuromuscular junction	GO:0051124	119	0.041
regulation of cellular component biogenesis	GO:0044087	201	0.041
organelle assembly	GO:0070925	198	0.041
negative regulation of gene expression	GO:0010629	387	0.040
positive regulation of rna biosynthetic process	GO:1902680	266	0.040
positive regulation of macromolecule metabolic process	GO:0010604	405	0.040
chemotaxis	GO:0006935	249	0.040
cellularization	GO:0007349	90	0.040
oocyte development	GO:0048599	124	0.039
membrane organization	GO:0061024	112	0.039	Fly
response to extracellular stimulus	GO:0009991	116	0.039
synaptic vesicle localization	GO:0097479	53	0.039
regulation of multi organism process	GO:0043900	131	0.039
anatomical structure homeostasis	GO:0060249	97	0.038
oocyte localization involved in germarium derived egg chamber formation	GO:0030720	12	0.038
organic acid metabolic process	GO:0006082	103	0.038
endocytosis	GO:0006897	310	0.037	Fly
positive regulation of gene expression	GO:0010628	290	0.037
regulation of synaptic growth at neuromuscular junction	GO:0008582	89	0.037
positive regulation of cellular component organization	GO:0051130	156	0.037	Fly
cellular protein complex assembly	GO:0043623	71	0.037
protein complex assembly	GO:0006461	200	0.036
karyosome formation	GO:0030717	22	0.036
negative regulation of protein metabolic process	GO:0051248	85	0.036
protein localization	GO:0008104	284	0.036
spindle localization	GO:0051653	22	0.036
modification dependent protein catabolic process	GO:0019941	78	0.036
protein catabolic process	GO:0030163	101	0.036
mitotic cytokinesis	GO:0000281	50	0.036
regulation of meiosis	GO:0040020	3	0.036
cell maturation	GO:0048469	144	0.035
male meiosis cytokinesis	GO:0007112	26	0.035
anterior posterior axis specification	GO:0009948	109	0.035
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.035
small molecule metabolic process	GO:0044281	305	0.035
proteasomal protein catabolic process	GO:0010498	59	0.034
spindle assembly	GO:0051225	80	0.033
sister chromatid segregation	GO:0000819	92	0.033
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.033
oocyte axis specification	GO:0007309	108	0.033
male gamete generation	GO:0048232	201	0.032
ovarian follicle cell development	GO:0030707	248	0.032
dna metabolic process	GO:0006259	227	0.032
regulation of cellular protein catabolic process	GO:1903362	44	0.031
modification dependent macromolecule catabolic process	GO:0043632	79	0.031
positive regulation of rna metabolic process	GO:0051254	271	0.031
negative regulation of cellular metabolic process	GO:0031324	382	0.030
appendage development	GO:0048736	401	0.030
positive regulation of multicellular organismal process	GO:0051240	143	0.030
vesicle fusion	GO:0006906	19	0.030	Fly
negative regulation of oskar mrna translation	GO:0007319	5	0.030
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.030
dorsal ventral pattern formation	GO:0009953	133	0.029
positive regulation of cellular biosynthetic process	GO:0031328	316	0.029
synapse organization	GO:0050808	196	0.028
single organism membrane fusion	GO:0044801	42	0.028	Fly
neuron projection guidance	GO:0097485	241	0.028
female meiosis chromosome segregation	GO:0016321	33	0.028
protein ubiquitination	GO:0016567	70	0.028
segmentation	GO:0035282	207	0.027
cognition	GO:0050890	141	0.027
autophagy	GO:0006914	108	0.026
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.026
protein modification by small protein conjugation	GO:0032446	79	0.026
organic substance transport	GO:0071702	257	0.026
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	54	0.026
oocyte dorsal ventral axis specification	GO:0007310	34	0.026
asymmetric cell division	GO:0008356	37	0.025
photoreceptor cell differentiation	GO:0046530	170	0.025
regulation of anatomical structure size	GO:0090066	163	0.025
establishment of organelle localization	GO:0051656	122	0.025
axonogenesis	GO:0007409	290	0.025
spindle assembly involved in male meiosis	GO:0007053	5	0.025
proteolysis	GO:0006508	192	0.025
intracellular transport	GO:0046907	228	0.025	Fly
axis specification	GO:0009798	167	0.024
cytokinesis	GO:0000910	90	0.024
exocrine system development	GO:0035272	162	0.024
phosphorylation	GO:0016310	294	0.024
chromatin organization	GO:0006325	207	0.024
salivary gland development	GO:0007431	162	0.024
regulation of cell cycle phase transition	GO:1901987	130	0.024
positive regulation of nervous system development	GO:0051962	69	0.023
positive regulation of cytoskeleton organization	GO:0051495	21	0.023
death	GO:0016265	284	0.023
meiosis ii	GO:0007135	23	0.023
single organism catabolic process	GO:0044712	228	0.023
regulation of protein complex disassembly	GO:0043244	29	0.023
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.023
regulation of phosphorus metabolic process	GO:0051174	210	0.023
protein k48 linked ubiquitination	GO:0070936	3	0.022
regulation of anatomical structure morphogenesis	GO:0022603	242	0.022
regulation of mitotic cell cycle	GO:0007346	190	0.022
compound eye development	GO:0048749	307	0.022
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.022
cellular protein localization	GO:0034613	160	0.022
cellular macromolecule catabolic process	GO:0044265	136	0.022
embryonic axis specification	GO:0000578	107	0.022
wing disc morphogenesis	GO:0007472	344	0.022
vesicle organization	GO:0016050	44	0.021	Fly
compound eye morphogenesis	GO:0001745	249	0.021
nuclear envelope organization	GO:0006998	7	0.021
response to organic cyclic compound	GO:0014070	89	0.021
syncytial blastoderm mitotic cell cycle	GO:0035186	21	0.021
secretion	GO:0046903	109	0.021
lateral inhibition	GO:0046331	206	0.021
response to other organism	GO:0051707	293	0.021
mitochondrion localization	GO:0051646	17	0.021
regulation of localization	GO:0032879	275	0.020	Fly
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.020
microtubule organizing center organization	GO:0031023	168	0.020
positive regulation of cell differentiation	GO:0045597	64	0.020
oxoacid metabolic process	GO:0043436	103	0.020
cell death	GO:0008219	279	0.020
appendage morphogenesis	GO:0035107	397	0.019
salivary gland cell autophagic cell death	GO:0035071	83	0.019
regulation of synapse assembly	GO:0051963	94	0.019
ovarian follicle cell stalk formation	GO:0030713	17	0.019
anterior posterior pattern specification	GO:0009952	136	0.019
learning or memory	GO:0007611	141	0.019
regulation of ras protein signal transduction	GO:0046578	93	0.018
positive regulation of growth	GO:0045927	75	0.018
regulation of synapse organization	GO:0050807	110	0.018
response to biotic stimulus	GO:0009607	294	0.018
actin filament organization	GO:0007015	126	0.018
cellular response to nutrient levels	GO:0031669	62	0.017
mitotic nuclear division	GO:0007067	213	0.017
regulation of cell differentiation	GO:0045595	302	0.017
positive regulation of exocytosis	GO:0045921	4	0.017
regulation of cellular component size	GO:0032535	98	0.017
vesicle localization	GO:0051648	55	0.017
establishment of mitochondrion localization	GO:0051654	7	0.017
response to external biotic stimulus	GO:0043207	293	0.017
cell proliferation	GO:0008283	299	0.017	Fly
regulation of cell cycle	GO:0051726	291	0.017
tissue morphogenesis	GO:0048729	297	0.017
negative regulation of catabolic process	GO:0009895	36	0.017
organic cyclic compound catabolic process	GO:1901361	168	0.017
imaginal disc derived appendage development	GO:0048737	399	0.017
telomere maintenance	GO:0000723	21	0.017
cellular protein catabolic process	GO:0044257	83	0.017
regulation of organelle organization	GO:0033043	196	0.017
gland morphogenesis	GO:0022612	145	0.016
columnar cuboidal epithelial cell development	GO:0002066	249	0.016
pirna metabolic process	GO:0034587	10	0.016
photoreceptor cell development	GO:0042461	96	0.016
germarium derived female germ line cyst formation	GO:0030727	42	0.016	Fly
skeletal muscle fiber development	GO:0048741	3	0.016
protein polymerization	GO:0051258	42	0.016
multicellular organism growth	GO:0035264	46	0.016	Fly
dna conformation change	GO:0071103	105	0.016
defense response to other organism	GO:0098542	225	0.016
single organism biosynthetic process	GO:0044711	206	0.016
g2 m transition of mitotic cell cycle	GO:0000086	19	0.016
regulation of synapse structure and activity	GO:0050803	128	0.016
actin cytoskeleton organization	GO:0030036	206	0.016
eye development	GO:0001654	323	0.015
salivary gland histolysis	GO:0035070	88	0.015
response to oxygen containing compound	GO:1901700	200	0.015
camera type eye development	GO:0043010	4	0.015
protein transport	GO:0015031	155	0.015
regulation of vesicle mediated transport	GO:0060627	59	0.015	Fly
dna repair	GO:0006281	54	0.015
anterior posterior axis specification embryo	GO:0008595	103	0.015
establishment of meiotic spindle orientation	GO:0051296	2	0.015
sensory organ morphogenesis	GO:0090596	260	0.015
positive regulation of developmental growth	GO:0048639	62	0.015
regulation of dna metabolic process	GO:0051052	34	0.015
endomembrane system organization	GO:0010256	119	0.015
positive regulation of organelle organization	GO:0010638	65	0.015
establishment of cell polarity	GO:0030010	40	0.014
protein maturation	GO:0051604	71	0.014
establishment of spindle orientation	GO:0051294	18	0.014
morphogenesis of follicular epithelium	GO:0016333	36	0.014
meiosis i	GO:0007127	59	0.014
negative regulation of rna metabolic process	GO:0051253	251	0.014
macroautophagy	GO:0016236	42	0.014
instar larval development	GO:0002168	55	0.014
organonitrogen compound biosynthetic process	GO:1901566	117	0.014
cellular response to extracellular stimulus	GO:0031668	64	0.013
positive regulation of cell communication	GO:0010647	250	0.013
spermatogenesis	GO:0007283	200	0.013
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.013
dendrite morphogenesis	GO:0048813	199	0.013
phagocytosis	GO:0006909	215	0.013
negative regulation of proteolysis involved in cellular protein catabolic process	GO:1903051	17	0.013
eye morphogenesis	GO:0048592	260	0.013
oocyte anterior posterior axis specification	GO:0007314	72	0.013
germarium derived female germ line cyst encapsulation	GO:0030708	8	0.013
gastrulation	GO:0007369	70	0.013
oocyte microtubule cytoskeleton polarization	GO:0008103	22	0.013
golgi organization	GO:0007030	66	0.013
regulation of protein metabolic process	GO:0051246	256	0.012
ncrna metabolic process	GO:0034660	43	0.012
negative regulation of protein catabolic process	GO:0042177	17	0.012
spindle organization	GO:0007051	253	0.012
actin filament capping	GO:0051693	2	0.012
rna processing	GO:0006396	147	0.012
dna recombination	GO:0006310	32	0.012
response to abiotic stimulus	GO:0009628	341	0.012
cellular response to chemical stimulus	GO:0070887	199	0.012
dna duplex unwinding	GO:0032508	16	0.012
centriole assembly	GO:0098534	24	0.012
establishment or maintenance of apical basal cell polarity	GO:0035088	34	0.012	Fly
regulation of catabolic process	GO:0009894	170	0.012
regulation of autophagy	GO:0010506	62	0.012
microtubule polymerization or depolymerization	GO:0031109	39	0.012
homeostatic process	GO:0042592	199	0.012
dna methylation or demethylation	GO:0044728	4	0.012
response to starvation	GO:0042594	97	0.012
gene silencing	GO:0016458	138	0.012
molting cycle	GO:0042303	56	0.011
negative regulation of cellular protein metabolic process	GO:0032269	85	0.011
lipid storage	GO:0019915	38	0.011
positive regulation of neuron apoptotic process	GO:0043525	1	0.011
myotube cell development	GO:0014904	3	0.011
positive regulation of signaling	GO:0023056	243	0.011
dna geometric change	GO:0032392	16	0.011
regulation of intracellular transport	GO:0032386	64	0.011
embryonic cleavage	GO:0040016	5	0.011
cell motility	GO:0048870	251	0.011
establishment of protein localization	GO:0045184	163	0.011
ubiquitin dependent protein catabolic process	GO:0006511	78	0.011
regulation of locomotion	GO:0040012	42	0.011
early endosome to late endosome transport	GO:0045022	3	0.011
anterograde axon cargo transport	GO:0008089	6	0.011
positive regulation of biosynthetic process	GO:0009891	316	0.011
protein dna complex assembly	GO:0065004	63	0.011
glial cell development	GO:0021782	27	0.011
regulation of proteasomal protein catabolic process	GO:0061136	39	0.011
photoreceptor cell fate commitment	GO:0046552	41	0.010
dephosphorylation	GO:0016311	51	0.010
cellular component assembly involved in morphogenesis	GO:0010927	151	0.010
cell cycle comprising mitosis without cytokinesis	GO:0033301	25	0.010
positive regulation of phosphorus metabolic process	GO:0010562	139	0.010
regulation of transposition	GO:0010528	13	0.010
germline ring canal formation	GO:0030725	13	0.010
cellular response to organic substance	GO:0071310	132	0.010
regulation of exit from mitosis	GO:0007096	7	0.010
ovarian nurse cell to oocyte transport	GO:0007300	27	0.010
organonitrogen compound metabolic process	GO:1901564	318	0.010
regulation of actin filament length	GO:0030832	27	0.010
synaptic vesicle recycling	GO:0036465	28	0.010
positive regulation of cell proliferation	GO:0008284	47	0.010
macromolecular complex disassembly	GO:0032984	37	0.010

Syx13 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.021
cardiovascular system disease	DOID:1287	0.012
essential hypertension	DOID:10825	0.012
vascular disease	DOID:178	0.012
artery disease	DOID:0050828	0.012
hypertension	DOID:10763	0.012

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