IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

CG4753 (Dmel_CG4753)

CG4753 gene product from transcript CG4753-RB

(Aliases: Dmel\CG4753)

Entrez: 39819
FLYBASE: FBgn0036622
UniProtKB: Q9VV49

Process Predictions
Disease Predictions

CG4753 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
single organism biosynthetic process	GO:0044711	206	0.154
vesicle mediated transport	GO:0016192	381	0.149
response to abiotic stimulus	GO:0009628	341	0.111
appendage morphogenesis	GO:0035107	397	0.105
organic substance transport	GO:0071702	257	0.093
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.090
homeostatic process	GO:0042592	199	0.086
phagocytosis	GO:0006909	215	0.079
small molecule metabolic process	GO:0044281	305	0.078
cholesterol transport	GO:0030301	2	0.076
post embryonic appendage morphogenesis	GO:0035120	385	0.076
cell proliferation	GO:0008283	299	0.076
appendage development	GO:0048736	401	0.073
organonitrogen compound metabolic process	GO:1901564	318	0.071
imaginal disc derived wing morphogenesis	GO:0007476	337	0.063
imaginal disc derived appendage development	GO:0048737	399	0.062
lipid biosynthetic process	GO:0008610	46	0.059
developmental growth	GO:0048589	280	0.059
negative regulation of cellular metabolic process	GO:0031324	382	0.058
organic acid metabolic process	GO:0006082	103	0.058
organic substance catabolic process	GO:1901575	308	0.056
cellular response to dna damage stimulus	GO:0006974	223	0.054
carboxylic acid metabolic process	GO:0019752	92	0.053
immune response	GO:0006955	246	0.052
growth	GO:0040007	359	0.051
lateral inhibition	GO:0046331	206	0.050
immune system process	GO:0002376	347	0.049
sterol homeostasis	GO:0055092	4	0.049
nitrogen compound transport	GO:0071705	85	0.047
endocytosis	GO:0006897	310	0.046
protein modification process	GO:0036211	438	0.045
cellular protein modification process	GO:0006464	438	0.044
cellular response to chemical stimulus	GO:0070887	199	0.042
meiotic cell cycle	GO:0051321	171	0.042
lipid storage	GO:0019915	38	0.042
negative regulation of response to stimulus	GO:0048585	258	0.041
negative regulation of signal transduction	GO:0009968	206	0.040
lipid localization	GO:0010876	54	0.040
rna localization	GO:0006403	115	0.040
nucleobase containing small molecule metabolic process	GO:0055086	174	0.038
amine metabolic process	GO:0009308	12	0.038
cholesterol homeostasis	GO:0042632	3	0.038
organophosphate metabolic process	GO:0019637	195	0.037
negative regulation of cell cycle	GO:0045786	116	0.037
l amino acid import	GO:0043092	2	0.036
cellular amine metabolic process	GO:0044106	12	0.036
regulation of localization	GO:0032879	275	0.036
cellular response to organic substance	GO:0071310	132	0.036
negative regulation of signaling	GO:0023057	219	0.036
negative regulation of rna biosynthetic process	GO:1902679	240	0.036
regionalization	GO:0003002	416	0.035
death	GO:0016265	284	0.034
l glutamate import	GO:0051938	1	0.034
maintenance of location	GO:0051235	73	0.034
body morphogenesis	GO:0010171	2	0.034
protein maturation	GO:0051604	71	0.034
regulation of cellular protein metabolic process	GO:0032268	243	0.034
cell cycle checkpoint	GO:0000075	95	0.034
regulation of cell cycle	GO:0051726	291	0.033
negative regulation of gene expression	GO:0010629	387	0.033
programmed cell death	GO:0012501	257	0.033
catabolic process	GO:0009056	409	0.033
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.032
regulation of lipid transport	GO:0032368	3	0.032
phosphatidic acid metabolic process	GO:0046473	1	0.032
chemical homeostasis	GO:0048878	92	0.032
neurological system process	GO:0050877	358	0.032
cellular amino acid metabolic process	GO:0006520	61	0.031
camera type eye development	GO:0043010	4	0.031
monocarboxylic acid metabolic process	GO:0032787	29	0.031
regulation of multi organism process	GO:0043900	131	0.030
negative regulation of cell communication	GO:0010648	223	0.030
cell motility	GO:0048870	251	0.029
cell cycle phase transition	GO:0044770	140	0.029
single organism catabolic process	GO:0044712	228	0.029
organelle fission	GO:0048285	340	0.029
response to biotic stimulus	GO:0009607	294	0.028
meiotic cell cycle process	GO:1903046	132	0.028
phosphorylation	GO:0016310	294	0.027
neutral lipid catabolic process	GO:0046461	3	0.027
nucleotide metabolic process	GO:0009117	161	0.027
positive regulation of lipid storage	GO:0010884	4	0.026
cellular response to endogenous stimulus	GO:0071495	80	0.026
regulation of cellular ketone metabolic process	GO:0010565	3	0.026
regulation of protein metabolic process	GO:0051246	256	0.026
response to external biotic stimulus	GO:0043207	293	0.026
microtubule organizing center organization	GO:0031023	168	0.025
establishment of localization in cell	GO:0051649	402	0.025
response to lipopolysaccharide	GO:0032496	4	0.024
response to organic substance	GO:0010033	284	0.024
glycerolipid catabolic process	GO:0046503	3	0.024
cell division	GO:0051301	248	0.024
peptidyl amino acid modification	GO:0018193	105	0.024
regulation of response to stress	GO:0080134	200	0.024
kidney development	GO:0001822	3	0.024
response to radiation	GO:0009314	155	0.024
cell death	GO:0008219	279	0.024
regulation of mitotic cell cycle	GO:0007346	190	0.024
proteolysis	GO:0006508	192	0.023
negative regulation of cellular protein metabolic process	GO:0032269	85	0.023
nucleoside phosphate metabolic process	GO:0006753	162	0.023
dorsal ventral pattern formation	GO:0009953	133	0.023
regulation of sterol transport	GO:0032371	1	0.023
organophosphate catabolic process	GO:0046434	112	0.023
chromatin silencing	GO:0006342	76	0.023
embryo development ending in birth or egg hatching	GO:0009792	152	0.023
fatty acid metabolic process	GO:0006631	20	0.023
cation transport	GO:0006812	110	0.023
regulation of phosphorus metabolic process	GO:0051174	210	0.023
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.022
positive regulation of signal transduction	GO:0009967	223	0.022
cytoskeleton dependent cytokinesis	GO:0061640	81	0.022
single organism behavior	GO:0044708	391	0.022
hormone metabolic process	GO:0042445	33	0.022
oxoacid metabolic process	GO:0043436	103	0.021
humoral immune response	GO:0006959	117	0.021
cellular macromolecule localization	GO:0070727	220	0.021
sodium dependent phosphate transport	GO:0044341	2	0.021
centrosome organization	GO:0051297	163	0.021
triglyceride catabolic process	GO:0019433	3	0.021
chromosome organization	GO:0051276	360	0.021
gland development	GO:0048732	191	0.021
response to other organism	GO:0051707	293	0.021
androgen metabolic process	GO:0008209	1	0.020
protein complex biogenesis	GO:0070271	201	0.020
regulation of hormone levels	GO:0010817	40	0.020
cellular component assembly involved in morphogenesis	GO:0010927	151	0.020
anion homeostasis	GO:0055081	3	0.020
purine containing compound metabolic process	GO:0072521	155	0.020
heterocycle catabolic process	GO:0046700	166	0.019
cellular catabolic process	GO:0044248	372	0.019
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.019
nuclear division	GO:0000280	332	0.019
acylglycerol biosynthetic process	GO:0046463	2	0.019
phospholipid homeostasis	GO:0055091	1	0.019
spermatid differentiation	GO:0048515	114	0.019
cellular ketone metabolic process	GO:0042180	24	0.019
purine ribonucleoside metabolic process	GO:0046128	127	0.018
respiratory system development	GO:0060541	213	0.018
positive regulation of transport	GO:0051050	92	0.018
phosphatidylethanolamine metabolic process	GO:0046337	1	0.018
response to hypoxia	GO:0001666	53	0.018
purine nucleoside catabolic process	GO:0006152	112	0.018
protein localization	GO:0008104	284	0.018
cellular lipid metabolic process	GO:0044255	83	0.018
regulation of cell proliferation	GO:0042127	163	0.018
regulation of phosphate metabolic process	GO:0019220	210	0.018
regulation of catalytic activity	GO:0050790	185	0.018
tube morphogenesis	GO:0035239	191	0.018
hindbrain development	GO:0030902	2	0.018
single organism intracellular transport	GO:1902582	207	0.018
transcription from rna polymerase ii promoter	GO:0006366	368	0.018
signal transduction by phosphorylation	GO:0023014	107	0.018
negative regulation of cellular biosynthetic process	GO:0031327	277	0.018
monovalent inorganic cation transport	GO:0015672	40	0.018
triglyceride biosynthetic process	GO:0019432	2	0.017
organonitrogen compound biosynthetic process	GO:1901566	117	0.017
single organism cellular localization	GO:1902580	180	0.017
mitotic cell cycle phase transition	GO:0044772	138	0.017
purine nucleoside metabolic process	GO:0042278	127	0.017
centrosome cycle	GO:0007098	137	0.017
regulation of catabolic process	GO:0009894	170	0.017
ribonucleotide metabolic process	GO:0009259	145	0.017
glycoprotein metabolic process	GO:0009100	41	0.017
regulation of cellular amine metabolic process	GO:0033238	3	0.017
regulation of transport	GO:0051049	181	0.017
wound healing	GO:0042060	75	0.017
protein phosphorylation	GO:0006468	169	0.017
positive regulation of signaling	GO:0023056	243	0.017
rna transport	GO:0050658	46	0.017
protein complex assembly	GO:0006461	200	0.016
response to light stimulus	GO:0009416	124	0.016
purine ribonucleotide biosynthetic process	GO:0009152	28	0.016
apoptotic process	GO:0006915	159	0.016
macromolecule catabolic process	GO:0009057	161	0.016
developmental maturation	GO:0021700	172	0.016
hormone catabolic process	GO:0042447	3	0.016
response to extracellular stimulus	GO:0009991	116	0.016
regulation of apoptotic process	GO:0042981	130	0.016
lipid metabolic process	GO:0006629	121	0.016
regulation of cell cycle process	GO:0010564	181	0.016
purine nucleotide catabolic process	GO:0006195	109	0.016
cation transmembrane transport	GO:0098655	88	0.016
imaginal disc pattern formation	GO:0007447	91	0.016
response to oxygen containing compound	GO:1901700	200	0.016
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.016
regulation of cellular localization	GO:0060341	136	0.016
response to wounding	GO:0009611	94	0.016
forebrain development	GO:0030900	2	0.016
nucleoside catabolic process	GO:0009164	112	0.016
regulation of response to dna damage stimulus	GO:2001020	23	0.015
regulation of antimicrobial humoral response	GO:0002759	50	0.015
positive regulation of macromolecule metabolic process	GO:0010604	405	0.015
acylglycerol catabolic process	GO:0046464	3	0.015
response to oxygen levels	GO:0070482	59	0.015
cellular response to hormone stimulus	GO:0032870	44	0.015
regulation of cholesterol transport	GO:0032374	1	0.015
positive regulation of biosynthetic process	GO:0009891	316	0.015
regulation of multicellular organismal development	GO:2000026	414	0.015
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.015
regulation of lipid storage	GO:0010883	22	0.015
nucleoside monophosphate metabolic process	GO:0009123	52	0.015
secondary metabolic process	GO:0019748	75	0.015
positive regulation of molecular function	GO:0044093	136	0.015
negative regulation of biosynthetic process	GO:0009890	277	0.015
purine ribonucleoside monophosphate metabolic process	GO:0009167	50	0.015
actin cytoskeleton organization	GO:0030036	206	0.015
response to organic cyclic compound	GO:0014070	89	0.015
wing disc pattern formation	GO:0035222	66	0.015
wing disc morphogenesis	GO:0007472	344	0.015
modification dependent macromolecule catabolic process	GO:0043632	79	0.014
glycosyl compound metabolic process	GO:1901657	127	0.014
cellular protein catabolic process	GO:0044257	83	0.014
purine nucleotide metabolic process	GO:0006163	146	0.014
regulation of cellular amino acid metabolic process	GO:0006521	0	0.014
purine ribonucleotide metabolic process	GO:0009150	145	0.014
nucleobase containing compound transport	GO:0015931	56	0.014
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.014
response to endogenous stimulus	GO:0009719	119	0.014
regulation of cell death	GO:0010941	173	0.014
cellular response to oxygen containing compound	GO:1901701	79	0.014
regulation of cellular response to stress	GO:0080135	89	0.014
small molecule biosynthetic process	GO:0044283	37	0.014
cellular ion homeostasis	GO:0006873	39	0.014
negative regulation of cell death	GO:0060548	81	0.014
negative regulation of programmed cell death	GO:0043069	72	0.014
protein transport	GO:0015031	155	0.014
cellular protein localization	GO:0034613	160	0.014
ethanolamine containing compound metabolic process	GO:0042439	4	0.014
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.014
epithelial cell differentiation	GO:0030855	322	0.014
meiotic nuclear division	GO:0007126	151	0.014
organonitrogen compound catabolic process	GO:1901565	128	0.014
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.014
regulation of phosphorylation	GO:0042325	147	0.014
embryonic morphogenesis	GO:0048598	206	0.014
mitochondrion organization	GO:0007005	65	0.013
chromosome segregation	GO:0007059	157	0.013
response to organophosphorus	GO:0046683	2	0.013
protein localization to organelle	GO:0033365	82	0.013
regulation of hydrolase activity	GO:0051336	97	0.013
defense response to bacterium	GO:0042742	178	0.013
glycosyl compound catabolic process	GO:1901658	112	0.013
carbohydrate derivative metabolic process	GO:1901135	217	0.013
response to copper ion	GO:0046688	4	0.013
ribonucleoside monophosphate metabolic process	GO:0009161	51	0.013
mitotic spindle organization	GO:0007052	220	0.013
regulation of intracellular signal transduction	GO:1902531	236	0.013
spermatogenesis	GO:0007283	200	0.013
negative regulation of cell cycle phase transition	GO:1901988	103	0.013
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.013
axonogenesis	GO:0007409	290	0.013
negative regulation of protein metabolic process	GO:0051248	85	0.013
intracellular transport	GO:0046907	228	0.013
negative regulation of cell differentiation	GO:0045596	143	0.013
dna metabolic process	GO:0006259	227	0.013
translation	GO:0006412	69	0.013
response to glucose	GO:0009749	2	0.013
cellular nitrogen compound catabolic process	GO:0044270	165	0.013
cellular macromolecule catabolic process	GO:0044265	136	0.013
cell migration	GO:0016477	238	0.013
intracellular signal transduction	GO:0035556	300	0.013
regulation of immune system process	GO:0002682	176	0.012
carbohydrate derivative biosynthetic process	GO:1901137	85	0.012
ion transport	GO:0006811	145	0.012
nucleoside triphosphate catabolic process	GO:0009143	108	0.012
positive regulation of sequestering of triglyceride	GO:0010890	1	0.012
regulation of sequestering of triglyceride	GO:0010889	3	0.012
ion transmembrane transport	GO:0034220	122	0.012
telencephalon development	GO:0021537	2	0.012
purine nucleoside monophosphate metabolic process	GO:0009126	50	0.012
regulation of molecular function	GO:0065009	217	0.012
retina development in camera type eye	GO:0060041	4	0.012
localization of cell	GO:0051674	257	0.012
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.012
defense response to other organism	GO:0098542	225	0.012
response to decreased oxygen levels	GO:0036293	58	0.012
regulation of growth	GO:0040008	233	0.012
ribonucleoside catabolic process	GO:0042454	112	0.012
response to temperature stimulus	GO:0009266	106	0.012
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	65	0.012
aromatic compound catabolic process	GO:0019439	166	0.012
regulation of immune response	GO:0050776	118	0.012
response to organonitrogen compound	GO:0010243	75	0.012
regulation of gene expression epigenetic	GO:0040029	128	0.012
protein processing	GO:0016485	68	0.012
developmental programmed cell death	GO:0010623	138	0.012
covalent chromatin modification	GO:0016569	106	0.012
autophagy	GO:0006914	108	0.012
dorsal ventral pattern formation imaginal disc	GO:0007450	51	0.012
histolysis	GO:0007559	102	0.011
digestive tract development	GO:0048565	149	0.011
mitotic cell cycle checkpoint	GO:0007093	88	0.011
positive regulation of cell communication	GO:0010647	250	0.011
very long chain fatty acid metabolic process	GO:0000038	4	0.011
ribonucleoside metabolic process	GO:0009119	127	0.011
autophagic cell death	GO:0048102	83	0.011
wnt signaling pathway	GO:0016055	98	0.011
negative regulation of developmental process	GO:0051093	201	0.011
biological adhesion	GO:0022610	138	0.011
regulation of programmed cell death	GO:0043067	152	0.011
salivary gland cell autophagic cell death	GO:0035071	83	0.011
cellular chemical homeostasis	GO:0055082	40	0.011
response to nitrogen compound	GO:1901698	90	0.011
oxidation reduction process	GO:0055114	123	0.011
antimicrobial humoral response	GO:0019730	99	0.011
response to calcium ion	GO:0051592	1	0.011
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.011
nucleotide catabolic process	GO:0009166	109	0.011
cellular homeostasis	GO:0019725	80	0.011
purine ribonucleoside catabolic process	GO:0046130	112	0.011
purine containing compound catabolic process	GO:0072523	112	0.011
heparan sulfate proteoglycan biosynthetic process	GO:0015012	10	0.011
endomembrane system organization	GO:0010256	119	0.011
aging	GO:0007568	143	0.011
alditol phosphate metabolic process	GO:0052646	2	0.011
connective tissue development	GO:0061448	3	0.011
regeneration	GO:0031099	16	0.011
chemosensory behavior	GO:0007635	106	0.011
cation homeostasis	GO:0055080	51	0.011
regulation of proteolysis	GO:0030162	87	0.011
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.010
response to monosaccharide	GO:0034284	4	0.010
lipid homeostasis	GO:0055088	33	0.010
response to nutrient levels	GO:0031667	114	0.010
regulation of cellular catabolic process	GO:0031329	157	0.010
negative regulation of organelle organization	GO:0010639	56	0.010
regulation of humoral immune response	GO:0002920	51	0.010
regulation of anatomical structure morphogenesis	GO:0022603	242	0.010
axis specification	GO:0009798	167	0.010
nucleoside phosphate biosynthetic process	GO:1901293	34	0.010
monocarboxylic acid transport	GO:0015718	3	0.010
chromatin modification	GO:0016568	147	0.010
developmental growth involved in morphogenesis	GO:0060560	65	0.010
compound eye development	GO:0048749	307	0.010
ribonucleoside monophosphate catabolic process	GO:0009158	39	0.010
cellular response to nitrogen compound	GO:1901699	51	0.010
toll signaling pathway	GO:0008063	25	0.010

CG4753 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of metabolism	DOID:0014667	0.115
disease of anatomical entity	DOID:7	0.057
acquired metabolic disease	DOID:0060158	0.044
glucose metabolism disease	DOID:4194	0.044
carbohydrate metabolism disease	DOID:0050013	0.044
type 2 diabetes mellitus	DOID:9352	0.044
diabetes mellitus	DOID:9351	0.044
hypotrichosis	DOID:4535	0.036
integumentary system disease	DOID:16	0.036
hair disease	DOID:421	0.036
inherited metabolic disorder	DOID:655	0.033
urinary system disease	DOID:18	0.029
kidney disease	DOID:557	0.025
renal tubular transport disease	DOID:447	0.025
musculoskeletal system disease	DOID:17	0.016
lipid metabolism disorder	DOID:3146	0.016
familial hyperlipidemia	DOID:1168	0.016
nervous system disease	DOID:863	0.016
bone disease	DOID:0080001	0.015
connective tissue disease	DOID:65	0.015
familial combined hyperlipidemia	DOID:13809	0.014
familial hypertriglyceridemia	DOID:0050527	0.013

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