Drosophila melanogaster

18 known processes

TppII (Dmel_CG3991)

tripeptidyl-peptidase II

(Aliases: anon-WO0118547.127,l(2)k14301,TPP2,dTPPII,TPPII,Dmel\CG3991,TPP II,CG3991,dTPP II)

TppII biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryo development ending in birth or egg hatchingGO:00097921520.433
body morphogenesisGO:001017120.211
cellular macromolecule catabolic processGO:00442651360.133
cellular catabolic processGO:00442483720.128
defense responseGO:00069523000.127
cellular macromolecular complex assemblyGO:00346221530.127
macromolecular complex assemblyGO:00650032560.115
catabolic processGO:00090564090.097
multicellular organismal agingGO:00102591400.077
g2 dna damage checkpointGO:0031572690.076
nuclear pore organizationGO:000699910.071
response to external biotic stimulusGO:00432072930.071
larval developmentGO:00021641040.070
positive regulation of macromolecule metabolic processGO:00106044050.068
protein complex biogenesisGO:00702712010.067
multicellular organismal reproductive behaviorGO:00330571100.067
regulation of cellular protein metabolic processGO:00322682430.066
positive regulation of cellular biosynthetic processGO:00313283160.062
snrna 3 end processingGO:0034472140.061
response to other organismGO:00517072930.056
cell proliferationGO:00082832990.056
organic substance catabolic processGO:19015753080.054
mitotic spindle organizationGO:00070522200.054
regulation of protein metabolic processGO:00512462560.053
rna 3 end processingGO:0031123450.051
nucleoside phosphate metabolic processGO:00067531620.050
macromolecule catabolic processGO:00090571610.050
rna processingGO:00063961470.049
oxoacid metabolic processGO:00434361030.047
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.046
cellular protein modification processGO:00064644380.045
regulation of developmental growthGO:00486381740.045
modification dependent protein catabolic processGO:0019941780.044
transcription from rna polymerase ii promoterGO:00063663680.044
protein catabolic processGO:00301631010.043
protein complex assemblyGO:00064612000.042
modification dependent macromolecule catabolic processGO:0043632790.041
exocrine system developmentGO:00352721620.041
salivary gland developmentGO:00074311620.041
positive regulation of cellular protein metabolic processGO:00322701180.040
mrna metabolic processGO:00160711240.040
salivary gland morphogenesisGO:00074351450.040
multi organism behaviorGO:00517051750.039
proteolysisGO:00065081920.039
regulation of cellular component biogenesisGO:00440872010.038
proteolysis involved in cellular protein catabolic processGO:0051603830.038
dna metabolic processGO:00062592270.037
spindle organizationGO:00070512530.036
snrna processingGO:0016180140.036
negative regulation of cellular biosynthetic processGO:00313272770.036
determination of adult lifespanGO:00083401370.036
response to biotic stimulusGO:00096072940.035
carboxylic acid metabolic processGO:0019752920.035
ubiquitin dependent protein catabolic processGO:0006511780.035
regulation of multicellular organismal developmentGO:20000264140.035
matingGO:00076181200.034
rna splicingGO:0008380830.034
cellular protein localizationGO:00346131600.033
positive regulation of developmental processGO:00510941430.032
regulation of cellular catabolic processGO:00313291570.032
mrna processingGO:00063971040.031
organic cyclic compound catabolic processGO:19013611680.031
regulation of organelle organizationGO:00330431960.031
regulation of response to stressGO:00801342000.031
cellular protein catabolic processGO:0044257830.030
agingGO:00075681430.030
dna templated transcription elongationGO:0006354180.030
purine ribonucleoside catabolic processGO:00461301120.030
cell divisionGO:00513012480.030
gland developmentGO:00487321910.029
innate immune responseGO:00450871440.028
organophosphate metabolic processGO:00196371950.028
cellular component disassemblyGO:0022411460.028
regulation of cellular protein catabolic processGO:1903362440.027
cellular protein complex assemblyGO:0043623710.027
developmental growthGO:00485892800.027
purine ribonucleotide metabolic processGO:00091501450.027
maintenance of locationGO:0051235730.027
Worm
posttranscriptional regulation of gene expressionGO:00106081450.026
establishment or maintenance of cell polarityGO:00071631670.026
mitotic nuclear divisionGO:00070672130.026
organic acid metabolic processGO:00060821030.026
purine containing compound metabolic processGO:00725211550.026
carbohydrate derivative metabolic processGO:19011352170.026
negative regulation of gene expressionGO:00106293870.025
nucleobase containing small molecule metabolic processGO:00550861740.025
small molecule metabolic processGO:00442813050.025
positive regulation of macromolecule biosynthetic processGO:00105572830.025
nucleoside metabolic processGO:00091161270.025
cell motilityGO:00488702510.025
rna polyadenylationGO:0043631120.024
positive regulation of biosynthetic processGO:00098913160.024
ubiquitin homeostasisGO:001099210.024
single organism behaviorGO:00447083910.024
aromatic compound catabolic processGO:00194391660.024
gland morphogenesisGO:00226121450.024
neuron deathGO:0070997270.023
enzyme linked receptor protein signaling pathwayGO:00071671790.023
reproductive system developmentGO:0061458740.022
mitotic g2 dna damage checkpointGO:0007095690.022
immune system processGO:00023763470.022
positive regulation of cell migrationGO:003033520.022
peptide metabolic processGO:0006518800.022
immune effector processGO:0002252980.021
negative regulation of mitotic cell cycle phase transitionGO:19019911030.021
ribonucleoside metabolic processGO:00091191270.021
heterocycle catabolic processGO:00467001660.021
negative regulation of nitrogen compound metabolic processGO:00511722650.021
regulation of antimicrobial peptide biosynthetic processGO:0002805380.021
deathGO:00162652840.020
meiotic cell cycleGO:00513211710.020
cell deathGO:00082192790.020
proteasomal protein catabolic processGO:0010498590.020
mrna polyadenylationGO:0006378110.020
regulation of immune system processGO:00026821760.020
positive regulation of protein metabolic processGO:00512471280.019
immune responseGO:00069552460.019
positive regulation of proteolysisGO:0045862520.019
ribose phosphate metabolic processGO:00196931450.019
ribonucleotide metabolic processGO:00092591450.018
er associated ubiquitin dependent protein catabolic processGO:003043330.018
regulation of cytoskeleton organizationGO:0051493890.018
organonitrogen compound catabolic processGO:19015651280.018
regulation of response to external stimulusGO:00321011150.018
cellular amino acid metabolic processGO:0006520610.018
regulation of mrna metabolic processGO:1903311720.018
negative regulation of response to stimulusGO:00485852580.018
phosphatidylinositol 3 kinase signalingGO:001406540.017
multi multicellular organism processGO:00447061230.017
regulation of proteolysisGO:0030162870.017
nucleotide catabolic processGO:00091661090.017
positive regulation of multicellular organismal processGO:00512401430.017
endocytosisGO:00068973100.017
regulation of protein complex assemblyGO:0043254420.017
protein targeting to nucleusGO:0044744510.016
regulation of synapse structure and activityGO:00508031280.016
rna interferenceGO:0016246270.016
dna repairGO:0006281540.016
nucleotide metabolic processGO:00091171610.016
mitotic dna integrity checkpointGO:0044774750.016
neurological system processGO:00508773580.016
purine ribonucleoside metabolic processGO:00461281270.016
negative regulation of neuron deathGO:1901215180.015
homeostatic processGO:00425921990.015
defense response to bacteriumGO:00427421780.015
negative regulation of cellular metabolic processGO:00313243820.015
protein complex disassemblyGO:0043241360.015
rna catabolic processGO:0006401370.015
regulation of cell developmentGO:00602842150.015
regulation of catalytic activityGO:00507901850.015
mitotic spindle elongationGO:0000022810.015
positive regulation of cellular component organizationGO:00511301560.015
regulation of protein stabilityGO:0031647430.015
response to bacteriumGO:00096171980.014
negative regulation of macromolecule biosynthetic processGO:00105582700.014
purine nucleotide metabolic processGO:00061631460.014
regulation of catabolic processGO:00098941700.014
reproductive behaviorGO:00190981220.014
response to lipopolysaccharideGO:003249640.014
ncrna 3 end processingGO:0043628170.014
positive regulation of cellular catabolic processGO:0031331950.014
mesenchymal cell developmentGO:001403110.014
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052240.014
positive regulation of cellular component biogenesisGO:0044089800.014
negative regulation of multicellular organismal processGO:00512411420.014
purine ribonucleoside triphosphate metabolic processGO:00092051190.014
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.013
regulation of nervous system developmentGO:00519602480.013
nucleobase containing compound catabolic processGO:00346551650.013
protein localizationGO:00081042840.013
localization of cellGO:00516742570.013
ncrna metabolic processGO:0034660430.013
purine nucleoside triphosphate metabolic processGO:00091441190.013
macromolecular complex disassemblyGO:0032984370.013
negative regulation of intrinsic apoptotic signaling pathwayGO:200124310.013
positive regulation of nervous system developmentGO:0051962690.013
nuclear importGO:0051170510.013
glycosyl compound metabolic processGO:19016571270.013
regulation of cellular amide metabolic processGO:0034248390.013
regulation of cellular ketone metabolic processGO:001056530.013
phagocytosisGO:00069092150.012
sex differentiationGO:0007548810.012
cell migrationGO:00164772380.012
taxisGO:00423303040.012
protein modification by small protein conjugation or removalGO:00706471060.012
positive regulation of gene expressionGO:00106282900.012
programmed cell deathGO:00125012570.012
regulation of immune responseGO:00507761180.012
protein transportGO:00150311550.012
amine metabolic processGO:0009308120.012
single organism catabolic processGO:00447122280.012
tissue deathGO:00162711020.012
cytoplasmic transportGO:00164821300.012
regulation of mrna processingGO:0050684710.012
ribonucleotide catabolic processGO:00092611090.012
regulation of cell cycleGO:00517262910.012
mesenchymal cell differentiationGO:004876210.011
organelle assemblyGO:00709251980.011
establishment of protein localizationGO:00451841630.011
behavioral response to painGO:004826630.011
cellular nitrogen compound catabolic processGO:00442701650.011
single organism cellular localizationGO:19025801800.011
carbohydrate derivative catabolic processGO:19011361180.011
cellular homeostasisGO:0019725800.011
regulation of cellular amine metabolic processGO:003323830.011
organonitrogen compound metabolic processGO:19015643180.011
snrna metabolic processGO:0016073140.011
protein importGO:0017038550.011
nucleoside monophosphate metabolic processGO:0009123520.011
cell cell signaling involved in cell fate commitmentGO:00451682100.011
rna localizationGO:00064031150.011
cellular amide metabolic processGO:0043603800.011
protein modification processGO:00362114380.011
positive regulation of rna biosynthetic processGO:19026802660.011
spindle elongationGO:0051231830.011
regulation of defense responseGO:00313471020.011
organonitrogen compound biosynthetic processGO:19015661170.011
protein deubiquitinationGO:0016579170.011
positive regulation of nucleobase containing compound metabolic processGO:00459353320.011
organic substance transportGO:00717022570.011
positive regulation of catabolic processGO:00098961050.011
regulation of synapse assemblyGO:0051963940.010
microtubule organizing center organizationGO:00310231680.010
regulation of dna templated transcription elongationGO:0032784170.010
single organism nuclear importGO:1902593510.010
small gtpase mediated signal transductionGO:0007264880.010
positive regulation of nitrogen compound metabolic processGO:00511733540.010
mitotic g2 m transition checkpointGO:0044818700.010
negative regulation of mitotic cell cycleGO:00459301090.010
mrna catabolic processGO:0006402330.010
response to alcoholGO:0097305950.010

TppII disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.037
cancerDOID:16200.019
disease of cellular proliferationDOID:1456600.019
nervous system diseaseDOID:86300.017