Drosophila melanogaster

25 known processes

msl-2 (Dmel_CG3241)

male-specific lethal 2

(Aliases: MSL-2,Dmel\CG3241,Msl2,MSL2,msl,CG3241,Msl-2,kmA,MSL,msl2,Msl 1-3,km(2)A)

msl-2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
histone h4 k16 acetylationGO:004398440.894
Human
histone h4 acetylationGO:0043967130.581
Human
negative regulation of gene expression epigeneticGO:0045814770.450
positive regulation of macromolecule biosynthetic processGO:00105572830.293
negative regulation of macromolecule biosynthetic processGO:00105582700.287
positive regulation of gene expressionGO:00106282900.257
negative regulation of gene expressionGO:00106293870.232
dosage compensationGO:0007549160.220
positive regulation of cellular biosynthetic processGO:00313283160.208
chromatin silencingGO:0006342760.198
negative regulation of nucleic acid templated transcriptionGO:19035072400.190
positive regulation of biosynthetic processGO:00098913160.172
positive regulation of transcription dna templatedGO:00458932660.166
negative regulation of cellular metabolic processGO:00313243820.161
negative regulation of rna biosynthetic processGO:19026792400.132
peptidyl lysine acetylationGO:0018394390.129
Human
peptidyl lysine modificationGO:0018205570.127
Human
negative regulation of chromatin silencingGO:003193690.127
positive regulation of nitrogen compound metabolic processGO:00511733540.123
regulation of gene silencingGO:0060968630.115
negative regulation of biosynthetic processGO:00098902770.106
regulation of chromatin silencingGO:0031935360.103
internal peptidyl lysine acetylationGO:0018393380.102
Human
protein modification processGO:00362114380.099
internal protein amino acid acetylationGO:0006475380.099
Human
positive regulation of rna metabolic processGO:00512542710.099
negative regulation of cellular biosynthetic processGO:00313272770.087
posttranscriptional regulation of gene expressionGO:00106081450.084
negative regulation of transcription dna templatedGO:00458922370.073
protein acylationGO:0043543420.069
Human
positive regulation of macromolecule metabolic processGO:00106044050.068
negative regulation of nitrogen compound metabolic processGO:00511722650.068
positive regulation of rna biosynthetic processGO:19026802660.067
positive regulation of nucleobase containing compound metabolic processGO:00459353320.066
positive regulation of nucleic acid templated transcriptionGO:19035082660.065
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.063
regulation of gene expression epigeneticGO:00400291280.062
chromatin modificationGO:00165681470.061
Human
positive regulation of gene expression epigeneticGO:0045815160.060
positive regulation of response to stimulusGO:00485843230.060
axon cargo transportGO:0008088290.053
regionalizationGO:00030024160.052
sensory perception of chemical stimulusGO:00076061160.050
synaptic transmissionGO:00072682880.048
sex determinationGO:0007530180.045
negative regulation of rna metabolic processGO:00512532510.045
smoothened signaling pathwayGO:0007224490.044
covalent chromatin modificationGO:00165691060.044
Human
mrna splicing via spliceosomeGO:0000398730.043
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101180.043
cell deathGO:00082192790.042
histone modificationGO:00165701060.042
Human
protein acetylationGO:0006473390.041
Human
anterograde axon cargo transportGO:000808960.040
cellular protein modification processGO:00064644380.040
negative regulation of nucleobase containing compound metabolic processGO:00459342610.038
regulation of immune system processGO:00026821760.038
chromatin organizationGO:00063252070.037
Human
negative regulation of cell communicationGO:00106482230.034
chromatin assembly or disassemblyGO:0006333520.034
programmed cell deathGO:00125012570.033
cell proliferationGO:00082832990.033
male mating behaviorGO:0060179700.033
rna splicingGO:0008380830.033
organelle fissionGO:00482853400.033
body morphogenesisGO:001017120.033
regulation of cellular amino acid metabolic processGO:000652100.031
chromosome organizationGO:00512763600.031
Human
transmembrane transportGO:00550851390.031
cellular homeostasisGO:0019725800.031
histone acetylationGO:0016573380.029
Human
matingGO:00076181200.029
chromatin remodelingGO:0006338720.028
regulation of alternative mrna splicing via spliceosomeGO:0000381600.028
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.028
zinc ion homeostasisGO:005506960.027
appendage morphogenesisGO:00351073970.027
wing disc morphogenesisGO:00074723440.026
eye photoreceptor cell developmentGO:0042462810.026
regulation of intracellular signal transductionGO:19025312360.025
cellular response to chemical stimulusGO:00708871990.025
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.025
cellular catabolic processGO:00442483720.025
growthGO:00400073590.025
positive regulation of cell communicationGO:00106472500.025
immune system processGO:00023763470.024
neurological system processGO:00508773580.024
peptidyl amino acid modificationGO:00181931050.023
Human
regulation of response to external stimulusGO:00321011150.023
establishment of synaptic vesicle localizationGO:0097480500.023
negative regulation of response to stimulusGO:00485852580.023
eye photoreceptor cell differentiationGO:00017541450.022
rna processingGO:00063961470.022
organic acid metabolic processGO:00060821030.022
imaginal disc derived wing morphogenesisGO:00074763370.021
small molecule metabolic processGO:00442813050.021
male courtship behavior veined wing generated song productionGO:0045433200.021
positive regulation of peptidase activityGO:0010952290.021
regulation of cell cycle processGO:00105641810.021
macromolecular complex assemblyGO:00650032560.020
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.020
alternative mrna splicing via spliceosomeGO:0000380600.020
defense responseGO:00069523000.020
response to painGO:004826530.020
homeostatic processGO:00425921990.020
oxoacid metabolic processGO:00434361030.019
positive regulation of cysteine type endopeptidase activityGO:2001056240.019
gene silencingGO:00164581380.019
positive regulation of signal transductionGO:00099672230.019
positive regulation of signalingGO:00230562430.019
synaptic vesicle localizationGO:0097479530.019
deathGO:00162652840.019
regulation of response to stressGO:00801342000.019
compound eye developmentGO:00487493070.018
photoreceptor cell differentiationGO:00465301700.018
organic substance catabolic processGO:19015753080.018
mrna metabolic processGO:00160711240.018
developmental growthGO:00485892800.018
mitotic cell cycle checkpointGO:0007093880.017
regulation of cellular ketone metabolic processGO:001056530.017
catabolic processGO:00090564090.017
female meiotic divisionGO:0007143700.017
spindle organizationGO:00070512530.017
translationGO:0006412690.017
vesicle mediated transportGO:00161923810.016
response to organic substanceGO:00100332840.016
stem cell differentiationGO:00488631170.016
carbohydrate derivative metabolic processGO:19011352170.016
regulation of transcription from rna polymerase ii promoterGO:00063573780.016
chromosome segregationGO:00070591570.016
carboxylic acid metabolic processGO:0019752920.016
limb developmentGO:006017310.016
regulation of rna splicingGO:0043484690.015
negative regulation of smoothened signaling pathwayGO:0045879160.015
axonogenesisGO:00074092900.015
negative regulation of neuron apoptotic processGO:0043524140.015
establishment of vesicle localizationGO:0051650510.015
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280230.015
cation transmembrane transportGO:0098655880.015
compound eye photoreceptor cell differentiationGO:00017511400.015
appendage developmentGO:00487364010.015
male courtship behavior veined wing extensionGO:0048065220.015
negative regulation of cellular response to oxidative stressGO:190040810.015
regulation of cellular amine metabolic processGO:003323830.015
response to abiotic stimulusGO:00096283410.015
reproductive system developmentGO:0061458740.015
vesicle localizationGO:0051648550.015
rna splicing via transesterification reactionsGO:0000375730.015
limb morphogenesisGO:003510810.015
regulation of cellular response to stressGO:0080135890.015
ion transmembrane transportGO:00342201220.015
response to other organismGO:00517072930.015
imaginal disc derived appendage developmentGO:00487373990.015
female meiosis chromosome segregationGO:0016321330.015
endocytosisGO:00068973100.015
organic cyclic compound catabolic processGO:19013611680.015
male courtship behaviorGO:0008049630.014
enzyme linked receptor protein signaling pathwayGO:00071671790.014
sensory perceptionGO:00076001960.014
somatic muscle developmentGO:0007525660.014
aromatic compound catabolic processGO:00194391660.014
chemical homeostasisGO:0048878920.014
protein complex biogenesisGO:00702712010.014
response to lipopolysaccharideGO:003249640.014
post embryonic appendage morphogenesisGO:00351203850.014
cellular ketone metabolic processGO:0042180240.014
meiotic cell cycleGO:00513211710.014
learningGO:0007612750.014
defense response to other organismGO:00985422250.014
regulation of notch signaling pathwayGO:00085931000.014
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.013
regulation of molecular functionGO:00650092170.013
ommochrome biosynthetic processGO:0006727190.013
inorganic ion transmembrane transportGO:0098660730.013
dna integrity checkpointGO:0031570810.013
heterochromatin assemblyGO:0031507130.013
regulation of phosphate metabolic processGO:00192202100.013
single organism membrane organizationGO:0044802930.013
phosphorylationGO:00163102940.013
posttranscriptional gene silencingGO:0016441460.013
microtubule based transportGO:0010970420.013
l glutamate importGO:005193810.013
positive regulation of endopeptidase activityGO:0010950260.013
dna metabolic processGO:00062592270.013
cell growthGO:00160491080.013
immune system developmentGO:0002520570.013
cell fate determinationGO:0001709910.013
dna packagingGO:0006323910.013
indole containing compound biosynthetic processGO:004243540.013
regulation of mrna metabolic processGO:1903311720.013
regulation of localizationGO:00328792750.012
histone exchangeGO:0043486210.012
ion homeostasisGO:0050801550.012
heterocycle catabolic processGO:00467001660.012
amine metabolic processGO:0009308120.012
detection of chemical stimulusGO:0009593930.012
regulation of response to oxidative stressGO:190288240.012
dendrite morphogenesisGO:00488131990.012
axon developmentGO:00615642970.012
meiotic cell cycle processGO:19030461320.012
g protein coupled receptor signaling pathwayGO:00071861360.012
determination of adult lifespanGO:00083401370.012
regulation of mrna splicing via spliceosomeGO:0048024640.012
open tracheal system developmentGO:00074242040.012
response to monosaccharideGO:003428440.012
cytoskeleton dependent intracellular transportGO:0030705440.012
organonitrogen compound metabolic processGO:19015643180.012
cell junction organizationGO:0034330570.012
multi organism reproductive behaviorGO:00447051210.012
meiotic chromosome segregationGO:0045132590.012
single fertilizationGO:0007338240.011
regulation of endocytosisGO:0030100370.011
developmental growth involved in morphogenesisGO:0060560650.011
cellular component assembly involved in morphogenesisGO:00109271510.011
golgi vesicle transportGO:0048193270.011
respiratory system developmentGO:00605412130.011
behavioral response to ethanolGO:0048149490.011
regulation of protein metabolic processGO:00512462560.011
cellular nitrogen compound catabolic processGO:00442701650.011
transcription from rna polymerase ii promoterGO:00063663680.011
connective tissue developmentGO:006144830.011
protein prenylationGO:001834230.011
morphogenesis of embryonic epitheliumGO:0016331940.011
negative regulation of sequence specific dna binding transcription factor activityGO:004343340.011
lipid metabolic processGO:00066291210.011
single organism catabolic processGO:00447122280.011
negative regulation of cell differentiationGO:00455961430.011
nucleotide excision repairGO:000628980.011
imaginal disc derived wing vein specificationGO:0007474480.011
nucleoside triphosphate catabolic processGO:00091431080.011
response to bacteriumGO:00096171980.011
mrna processingGO:00063971040.011
stem cell divisionGO:0017145690.011
response to starvationGO:0042594970.011
meiosis iGO:0007127590.011
establishment of localization in cellGO:00516494020.011
regulation of cell cycleGO:00517262910.011
regulation of smoothened signaling pathwayGO:0008589280.011
regulation of mrna processingGO:0050684710.011
gland morphogenesisGO:00226121450.011
bmp signaling pathwayGO:0030509270.011
apoptotic process involved in morphogenesisGO:006056130.010
defense response to bacteriumGO:00427421780.010
cell cycle checkpointGO:0000075950.010
posttranscriptional gene silencing by rnaGO:0035194450.010
ovarian follicle cell stalk formationGO:0030713170.010
dna damage checkpointGO:0000077780.010
photoreceptor cell developmentGO:0042461960.010
stress activated protein kinase signaling cascadeGO:0031098550.010
establishment of organelle localizationGO:00516561220.010
negative regulation of neuron deathGO:1901215180.010
signal transduction by phosphorylationGO:00230141070.010
imaginal disc growthGO:0007446370.010
midgut developmentGO:0007494230.010
cell projection assemblyGO:0030031940.010
cell fate specificationGO:0001708710.010
regulation of cell substrate adhesionGO:001081020.010
cell divisionGO:00513012480.010

msl-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.036
disease of metabolismDOID:001466700.018
organ system cancerDOID:005068600.017
cancerDOID:16200.017
disease of cellular proliferationDOID:1456600.017
cardiovascular system diseaseDOID:128700.013
acquired metabolic diseaseDOID:006015800.012
nervous system diseaseDOID:86300.011
musculoskeletal system diseaseDOID:1700.010