Drosophila melanogaster

40 known processes

eIF-1A (Dmel_CG8053)

Eukaryotic initiation factor 1A

(Aliases: CG8053,eIF1A,Group I,EP(3)0935,group I,EP935,anon-EST:Posey4,eIF-4c,anon-EST:Liang-2.3,clone 2.3,D-eIF4c,D-eIF1A,Dmel\CG8053)

eIF-1A biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of gene expressionGO:00106282900.301
establishment of localization in cellGO:00516494020.251
intracellular transportGO:00469072280.182
positive regulation of macromolecule metabolic processGO:00106044050.161
positive regulation of macromolecule biosynthetic processGO:00105572830.157
posttranscriptional regulation of gene expressionGO:00106081450.155
positive regulation of rna biosynthetic processGO:19026802660.153
regulation of transcription from rna polymerase ii promoterGO:00063573780.145
positive regulation of cellular biosynthetic processGO:00313283160.141
positive regulation of nucleic acid templated transcriptionGO:19035082660.136
dorsal ventral pattern formationGO:00099531330.133
cytoplasmic transportGO:00164821300.119
negative regulation of mitotic cell cycleGO:00459301090.117
modification dependent macromolecule catabolic processGO:0043632790.110
positive regulation of rna metabolic processGO:00512542710.105
positive regulation of transcription dna templatedGO:00458932660.103
single organism intracellular transportGO:19025822070.101
negative regulation of mitotic cell cycle phase transitionGO:19019911030.097
regulation of gene expression epigeneticGO:00400291280.093
macromolecule catabolic processGO:00090571610.092
transcription from rna polymerase ii promoterGO:00063663680.085
immune system processGO:00023763470.084
response to biotic stimulusGO:00096072940.082
organic substance transportGO:00717022570.082
mitotic cell cycle phase transitionGO:00447721380.079
positive regulation of biosynthetic processGO:00098913160.076
cellular macromolecule localizationGO:00707272200.075
positive regulation of nucleobase containing compound metabolic processGO:00459353320.075
regulation of cell cycle phase transitionGO:19019871300.074
homeostatic processGO:00425921990.072
stem cell differentiationGO:00488631170.072
protein catabolic processGO:00301631010.071
organic substance catabolic processGO:19015753080.071
chemical homeostasisGO:0048878920.070
mitotic dna damage checkpointGO:0044773740.069
cell cycle phase transitionGO:00447701400.069
male gamete generationGO:00482322010.068
cellular response to dna damage stimulusGO:00069742230.066
proteasomal protein catabolic processGO:0010498590.060
positive regulation of transportGO:0051050920.058
organonitrogen compound metabolic processGO:19015643180.057
dna repairGO:0006281540.057
gene silencingGO:00164581380.056
cell cycle checkpointGO:0000075950.056
negative regulation of cell cycle processGO:00109481090.056
regulation of mitotic cell cycle phase transitionGO:19019901300.056
negative regulation of cellular metabolic processGO:00313243820.052
stem cell developmentGO:0048864790.052
columnar cuboidal epithelial cell differentiationGO:00020652560.051
post embryonic appendage morphogenesisGO:00351203850.050
imaginal disc derived wing morphogenesisGO:00074763370.050
regulation of localizationGO:00328792750.049
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.049
negative regulation of cell cycle phase transitionGO:19019881030.049
nucleocytoplasmic transportGO:0006913720.049
dna integrity checkpointGO:0031570810.048
cellular component assembly involved in morphogenesisGO:00109271510.048
stem cell maintenanceGO:0019827670.047
rna localizationGO:00064031150.047
imaginal disc derived appendage morphogenesisGO:00351143950.046
response to other organismGO:00517072930.046
agingGO:00075681430.046
catabolic processGO:00090564090.045
regulation of transportGO:00510491810.045
cellular macromolecule catabolic processGO:00442651360.045
cell divisionGO:00513012480.045
imaginal disc derived appendage developmentGO:00487373990.044
regulation of cell cycleGO:00517262910.044
response to bacteriumGO:00096171980.044
eye developmentGO:00016543230.043
regulation of multicellular organismal developmentGO:20000264140.043
single organism biosynthetic processGO:00447112060.043
appendage developmentGO:00487364010.043
negative regulation of developmental processGO:00510932010.042
regulation of anatomical structure morphogenesisGO:00226032420.042
smoothened signaling pathwayGO:0007224490.042
regulation of response to stressGO:00801342000.041
negative regulation of cell differentiationGO:00455961430.041
cell migrationGO:00164772380.041
growthGO:00400073590.040
epithelial cell developmentGO:00020642740.040
proteolysisGO:00065081920.040
columnar cuboidal epithelial cell developmentGO:00020662490.040
negative regulation of cellular biosynthetic processGO:00313272770.039
rna processingGO:00063961470.039
epithelial cell differentiationGO:00308553220.039
secretionGO:00469031090.039
mitotic dna integrity checkpointGO:0044774750.039
mitotic nuclear divisionGO:00070672130.038
embryo development ending in birth or egg hatchingGO:00097921520.038
imaginal disc derived wing vein specificationGO:0007474480.038
protein transportGO:00150311550.038
negative regulation of nitrogen compound metabolic processGO:00511722650.038
mrna metabolic processGO:00160711240.038
regulation of cell cycle processGO:00105641810.037
nitrogen compound transportGO:0071705850.037
mitotic cell cycle checkpointGO:0007093880.036
translationGO:0006412690.036
cell proliferationGO:00082832990.035
appendage morphogenesisGO:00351073970.035
compound eye morphogenesisGO:00017452490.034
muscle structure developmentGO:00610612240.034
negative regulation of cell cycleGO:00457861160.034
body morphogenesisGO:001017120.033
negative regulation of gene expressionGO:00106293870.033
cellular catabolic processGO:00442483720.033
sensory organ morphogenesisGO:00905962600.033
regulation of mitotic cell cycleGO:00073461900.032
response to external biotic stimulusGO:00432072930.032
endocytosisGO:00068973100.032
compound eye developmentGO:00487493070.031
defense response to bacteriumGO:00427421780.031
response to light stimulusGO:00094161240.031
protein modification processGO:00362114380.031
dendrite morphogenesisGO:00488131990.031
proteolysis involved in cellular protein catabolic processGO:0051603830.031
negative regulation of rna biosynthetic processGO:19026792400.031
imaginal disc derived leg morphogenesisGO:0007480800.030
ubiquitin dependent protein catabolic processGO:0006511780.030
dna damage checkpointGO:0000077780.030
cation homeostasisGO:0055080510.030
dna metabolic processGO:00062592270.030
negative regulation of nucleic acid templated transcriptionGO:19035072400.030
carbohydrate derivative metabolic processGO:19011352170.029
modification dependent protein catabolic processGO:0019941780.029
macromolecular complex disassemblyGO:0032984370.029
ovarian follicle cell developmentGO:00307072480.029
dna conformation changeGO:00711031050.029
organelle fissionGO:00482853400.029
secretion by cellGO:00329401010.029
regulation of cellular response to stressGO:0080135890.028
jak stat cascadeGO:0007259490.028
cellular protein modification processGO:00064644380.028
regulation of notch signaling pathwayGO:00085931000.028
eggshell formationGO:00307031050.027
imaginal disc pattern formationGO:0007447910.027
single organism carbohydrate metabolic processGO:0044723720.027
leg disc morphogenesisGO:0007478800.027
regulation of epithelial cell proliferationGO:005067840.027
chorion containing eggshell formationGO:00073041050.027
protein localizationGO:00081042840.027
regionalizationGO:00030024160.027
detection of stimulusGO:00516061560.026
chaeta morphogenesisGO:0008407420.026
regulation of developmental growthGO:00486381740.026
chromosome organizationGO:00512763600.025
mitotic spindle elongationGO:0000022810.025
defense responseGO:00069523000.025
nuclear divisionGO:00002803320.025
cellular protein complex disassemblyGO:0043624350.024
protein modification by small protein conjugationGO:0032446790.024
biological adhesionGO:00226101380.023
cell motilityGO:00488702510.023
eye morphogenesisGO:00485922600.023
multicellular organismal agingGO:00102591400.023
microtubule based movementGO:0007018510.023
cellular protein catabolic processGO:0044257830.023
spindle elongationGO:0051231830.022
negative regulation of biosynthetic processGO:00098902770.022
adult behaviorGO:00305341370.022
carbohydrate metabolic processGO:0005975820.022
response to organic substanceGO:00100332840.022
cell deathGO:00082192790.022
organelle assemblyGO:00709251980.022
negative regulation of cell cycle g1 s phase transitionGO:1902807130.022
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.022
gland developmentGO:00487321910.022
rrna processingGO:000636430.022
organonitrogen compound biosynthetic processGO:19015661170.021
regulation of cytoplasmic transportGO:1903649470.021
regulation of cellular localizationGO:00603411360.021
negative regulation of macromolecule biosynthetic processGO:00105582700.021
regulation of immune system processGO:00026821760.021
intracellular protein transmembrane importGO:004474340.021
oocyte developmentGO:00485991240.021
response to lipopolysaccharideGO:003249640.021
cell cell signaling involved in cell fate commitmentGO:00451682100.021
mitotic g2 dna damage checkpointGO:0007095690.021
single organism behaviorGO:00447083910.021
intracellular signal transductionGO:00355563000.020
wing disc morphogenesisGO:00074723440.020
negative regulation of growth of symbiont involved in interaction with hostGO:004414690.020
phagocytosisGO:00069092150.020
spermatogenesisGO:00072832000.020
response to oxygen containing compoundGO:19017002000.020
notch signaling pathwayGO:00072191200.020
metal ion transportGO:0030001740.020
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.020
organophosphate metabolic processGO:00196371950.019
regulation of translationGO:0006417560.019
protein ubiquitinationGO:0016567700.019
immune responseGO:00069552460.019
regulation of cell cycle g1 s phase transitionGO:1902806230.019
determination of adult lifespanGO:00083401370.019
cellular protein localizationGO:00346131600.019
interspecies interaction between organismsGO:0044419160.019
embryonic development via the syncytial blastodermGO:00017001480.019
rna transportGO:0050658460.019
positive regulation of molecular functionGO:00440931360.019
cellular response to lipopolysaccharideGO:007122230.019
protein glycosylationGO:0006486320.018
response to radiationGO:00093141550.018
cellular cation homeostasisGO:0030003380.018
cellular ion homeostasisGO:0006873390.018
eggshell chorion assemblyGO:0007306660.018
cellular nitrogen compound catabolic processGO:00442701650.018
centrosome organizationGO:00512971630.018
response to alcoholGO:0097305950.018
actin filament based processGO:00300292200.018
nucleobase containing compound transportGO:0015931560.018
regulation of intracellular transportGO:0032386640.018
purine nucleoside metabolic processGO:00422781270.017
vesicle mediated transportGO:00161923810.017
intracellular protein transmembrane transportGO:006500240.017
striated muscle cell differentiationGO:0051146900.017
mitochondrion organizationGO:0007005650.017
regulation of g1 s transition of mitotic cell cycleGO:2000045230.017
larval developmentGO:00021641040.017
intracellular protein transportGO:00068861040.017
negative regulation of transcription dna templatedGO:00458922370.017
gliogenesisGO:0042063800.017
positive regulation of nitrogen compound metabolic processGO:00511733540.017
salivary gland histolysisGO:0035070880.017
regulation of epithelial cell differentiationGO:003085640.017
regulation of catalytic activityGO:00507901850.017
lateral inhibitionGO:00463312060.017
positive regulation of cell communicationGO:00106472500.016
regulation of cellular protein metabolic processGO:00322682430.016
organic acid metabolic processGO:00060821030.016
wing disc pattern formationGO:0035222660.016
nucleoside triphosphate metabolic processGO:00091411200.016
positive regulation of cell cycleGO:0045787430.016
chemosensory behaviorGO:00076351060.016
g1 s transition of mitotic cell cycleGO:0000082310.016
negative regulation of rna metabolic processGO:00512532510.016
membrane buddingGO:000690040.016
positive regulation of signal transductionGO:00099672230.016
ion homeostasisGO:0050801550.016
nuclear transportGO:0051169720.016
protein complex disassemblyGO:0043241360.016
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.016
response to abiotic stimulusGO:00096283410.015
negative regulation of epithelial cell proliferationGO:005068040.015
cell cycle g1 s phase transitionGO:0044843310.015
g2 dna damage checkpointGO:0031572690.015
compound eye photoreceptor developmentGO:0042051780.015
oocyte axis specificationGO:00073091080.015
negative regulation of multicellular organismal processGO:00512411420.015
establishment of protein localizationGO:00451841630.015
establishment of rna localizationGO:0051236470.015
stress activated protein kinase signaling cascadeGO:0031098550.015
nucleobase containing compound catabolic processGO:00346551650.015
single organism membrane buddingGO:190259120.015
hematopoietic or lymphoid organ developmentGO:0048534570.015
carbohydrate derivative biosynthetic processGO:1901137850.015
wing disc dorsal ventral pattern formationGO:0048190470.015
regulation of phosphate metabolic processGO:00192202100.015
defense response to other organismGO:00985422250.015
chromosome segregationGO:00070591570.014
developmental growthGO:00485892800.014
morphogenesis of an epitheliumGO:00020092760.014
single organism cellular localizationGO:19025801800.014
regulation of phosphorylationGO:00423251470.014
detection of abiotic stimulusGO:0009582660.014
cell junction assemblyGO:0034329420.014
heterocycle catabolic processGO:00467001660.014
regulation of cell shapeGO:00083601130.014
purine nucleoside triphosphate metabolic processGO:00091441190.014
protein modification by small protein conjugation or removalGO:00706471060.014
mitotic cell cycle embryonicGO:0045448380.014
mrna polyadenylationGO:0006378110.014
regulation of organelle organizationGO:00330431960.014
positive regulation of signalingGO:00230562430.014
mesenchymal cell differentiationGO:004876210.014
negative regulation of protein metabolic processGO:0051248850.014
protein dna complex assemblyGO:0065004630.014
developmental maturationGO:00217001720.014
single organism catabolic processGO:00447122280.014
dorsal ventral axis specificationGO:0009950660.014
molting cycleGO:0042303560.014
er associated ubiquitin dependent protein catabolic processGO:003043330.013
regulation of proteasomal protein catabolic processGO:0061136390.013
regulation of growthGO:00400082330.013
dendrite developmentGO:00163582040.013
negative regulation of gene expression epigeneticGO:0045814770.013
positive regulation of cell migrationGO:003033520.013
maintenance of locationGO:0051235730.013
protein complex biogenesisGO:00702712010.013
mitotic sister chromatid segregationGO:0000070870.013
mesenchymal cell developmentGO:001403110.013
nucleobase containing small molecule metabolic processGO:00550861740.013
endosome transport via multivesicular body sorting pathwayGO:0032509120.013
nucleoside phosphate metabolic processGO:00067531620.013
regulation of protein metabolic processGO:00512462560.013
translational initiationGO:0006413110.013
camera type eye developmentGO:004301040.013
salivary gland cell autophagic cell deathGO:0035071830.012
negative regulation of immune system processGO:0002683500.012
regulation of cell proliferationGO:00421271630.012
mitotic spindle organizationGO:00070522200.012
central nervous system developmentGO:00074172010.012
negative regulation of signal transductionGO:00099682060.012
deathGO:00162652840.012
negative regulation of nucleobase containing compound metabolic processGO:00459342610.012
immune response activating signal transductionGO:000275720.012
cell adhesionGO:00071551360.012
purine ribonucleoside triphosphate catabolic processGO:00092071080.012
rna 3 end processingGO:0031123450.012
regulation of cellular ketone metabolic processGO:001056530.012
chaeta developmentGO:0022416970.012
regulation of mrna 3 end processingGO:003144070.012
protein complex assemblyGO:00064612000.012
translational terminationGO:000641520.012
glial cell differentiationGO:0010001350.012
microtubule organizing center organizationGO:00310231680.012
small molecule metabolic processGO:00442813050.012
regulation of proteolysisGO:0030162870.012
chromatin silencingGO:0006342760.012
mrna 3 end processingGO:0031124280.012
protein localization to organelleGO:0033365820.012
germarium derived egg chamber formationGO:00072931010.012
regulation of protein transportGO:0051223570.012
meiotic cell cycleGO:00513211710.012
dorsal appendage formationGO:0046843470.012
aromatic compound catabolic processGO:00194391660.011
protein importGO:0017038550.011
ribose phosphate metabolic processGO:00196931450.011
mesoderm developmentGO:0007498780.011
regulation of nucleocytoplasmic transportGO:0046822350.011
regulation of vesicle mediated transportGO:0060627590.011
embryonic pattern specificationGO:00098801740.011
aggressive behaviorGO:0002118630.011
posttranscriptional gene silencingGO:0016441460.011
pole plasm assemblyGO:0007315610.011
neurological system processGO:00508773580.011
organic cyclic compound catabolic processGO:19013611680.011
posttranscriptional gene silencing by rnaGO:0035194450.011
humoral immune responseGO:00069591170.011
postreplication repairGO:000630120.011
regulation of cell morphogenesisGO:00226041630.011
regulation of cellular catabolic processGO:00313291570.011
gland morphogenesisGO:00226121450.011
regulation of endocytosisGO:0030100370.011
muscle cell developmentGO:0055001500.011
positive regulation of proteolysisGO:0045862520.011
chromatin modificationGO:00165681470.011
nucleotide metabolic processGO:00091171610.011
cell growthGO:00160491080.011
cellular homeostasisGO:0019725800.011
cell maturationGO:00484691440.011
protein targetingGO:0006605640.011
behavioral response to ethanolGO:0048149490.011
pigmentationGO:0043473750.011
nucleoside triphosphate catabolic processGO:00091431080.011
germarium derived oocyte differentiationGO:0030706290.011
antimicrobial humoral responseGO:0019730990.011
immune system developmentGO:0002520570.011
dna templated transcription elongationGO:0006354180.011
protein k48 linked ubiquitinationGO:007093630.011
embryonic morphogenesisGO:00485982060.011
cytoplasm organizationGO:0007028640.011
detection of external stimulusGO:0009581660.011
signal releaseGO:0023061490.011
oocyte differentiationGO:00099941450.011
negative regulation of cellular protein metabolic processGO:0032269850.011
spinal cord developmentGO:002151010.011
positive regulation of multicellular organismal processGO:00512401430.010
covalent chromatin modificationGO:00165691060.010
developmental programmed cell deathGO:00106231380.010
compound eye photoreceptor cell differentiationGO:00017511400.010
developmental pigmentationGO:0048066680.010
histone ubiquitinationGO:001657440.010
positive regulation of intracellular transportGO:0032388420.010
regulation of pole plasm oskar mrna localizationGO:0007317270.010
purine ribonucleoside catabolic processGO:00461301120.010
eye pigmentationGO:0048069430.010
negative regulation of neural precursor cell proliferationGO:2000178270.010
actin cytoskeleton organizationGO:00300362060.010
hematopoietic progenitor cell differentiationGO:000224410.010
cellular response to biotic stimulusGO:007121640.010
ion transportGO:00068111450.010
pigment metabolic processGO:0042440840.010

eIF-1A disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.056
nervous system diseaseDOID:86300.019
organ system cancerDOID:005068600.015
disease of cellular proliferationDOID:1456600.015
cancerDOID:16200.015