Drosophila melanogaster

160 known processes

mad2 (Dmel_CG17498)

CG17498 gene product from transcript CG17498-RA

(Aliases: Mad2,Dmel\CG17498,MAD2,CG17498)

mad2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of cellular metabolic processGO:00313243820.733
meiotic cell cycle processGO:19030461320.634
negative regulation of cell cycle processGO:00109481090.480
organelle fissionGO:00482853400.479
mitotic cell cycle phase transitionGO:00447721380.451
meiotic nuclear divisionGO:00071261510.449
meiotic cell cycleGO:00513211710.355
regulation of cell cycle phase transitionGO:19019871300.350
cellular response to dna damage stimulusGO:00069742230.344
regulation of mitotic cell cycleGO:00073461900.314
cell cycle phase transitionGO:00447701400.312
regulation of mitotic cell cycle phase transitionGO:19019901300.270
meiosis iGO:0007127590.258
negative regulation of mitotic cell cycleGO:00459301090.257
negative regulation of gene expressionGO:00106293870.237
negative regulation of mitotic cell cycle phase transitionGO:19019911030.230
negative regulation of chromosome segregationGO:0051985140.215
regulation of cell differentiationGO:00455953020.206
regulation of cellular protein metabolic processGO:00322682430.175
dna metabolic processGO:00062592270.172
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.172
mitotic sister chromatid separationGO:0051306300.160
dna repairGO:0006281540.142
cell divisionGO:00513012480.132
negative regulation of cell cycle phase transitionGO:19019881030.117
regulation of nervous system developmentGO:00519602480.116
stem cell divisionGO:0017145690.109
regulation of multicellular organismal developmentGO:20000264140.104
mitotic cell cycle checkpointGO:0007093880.100
innate immune responseGO:00450871440.090
negative regulation of cell cycleGO:00457861160.081
positive regulation of nitrogen compound metabolic processGO:00511733540.080
organelle assemblyGO:00709251980.079
chromosome segregationGO:00070591570.077
mitotic spindle organizationGO:00070522200.076
catabolic processGO:00090564090.074
microtubule cytoskeleton organization involved in mitosisGO:1902850520.073
negative regulation of macromolecule biosynthetic processGO:00105582700.067
neuronal stem cell divisionGO:0036445350.066
cell proliferationGO:00082832990.065
purine ribonucleoside triphosphate metabolic processGO:00092051190.065
negative regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032435160.065
cellular protein localizationGO:00346131600.064
regulation of phosphate metabolic processGO:00192202100.063
asymmetric neuroblast divisionGO:0055059330.063
dna conformation changeGO:00711031050.063
ribonucleoside triphosphate metabolic processGO:00091991190.062
mitotic dna integrity checkpointGO:0044774750.062
regulation of mitosisGO:0007088560.061
mrna processingGO:00063971040.060
spindle organizationGO:00070512530.058
regulation of cell cycle processGO:00105641810.058
neural precursor cell proliferationGO:0061351750.058
negative regulation of chromosome organizationGO:2001251190.057
cytoplasmic transportGO:00164821300.055
spindle assembly involved in mitosisGO:0090307500.055
negative regulation of cellular biosynthetic processGO:00313272770.054
asymmetric stem cell divisionGO:0098722490.050
establishment or maintenance of cell polarityGO:00071631670.050
proteasomal protein catabolic processGO:0010498590.050
protein localizationGO:00081042840.050
spindle checkpointGO:0031577110.050
ubiquitin dependent protein catabolic processGO:0006511780.047
regulation of cell cycleGO:00517262910.047
negative regulation of nucleobase containing compound metabolic processGO:00459342610.047
cell cycle g1 s phase transitionGO:0044843310.046
positive regulation of macromolecule metabolic processGO:00106044050.046
nuclear transportGO:0051169720.045
cellular macromolecule localizationGO:00707272200.044
single organism intracellular transportGO:19025822070.044
olfactory behaviorGO:0042048970.044
cellular nitrogen compound catabolic processGO:00442701650.044
organic substance catabolic processGO:19015753080.044
metaphase anaphase transition of cell cycleGO:0044784280.044
negative regulation of mitotic sister chromatid separationGO:2000816130.043
positive regulation of macromolecule biosynthetic processGO:00105572830.042
asymmetric protein localizationGO:0008105330.041
dna recombinationGO:0006310320.041
mitotic cytokinesisGO:0000281500.041
regulation of cell developmentGO:00602842150.041
negative regulation of rna metabolic processGO:00512532510.040
body morphogenesisGO:001017120.039
organic substance transportGO:00717022570.038
spermatogenesisGO:00072832000.038
regulation of organelle organizationGO:00330431960.037
ribonucleoside metabolic processGO:00091191270.036
negative regulation of nucleic acid templated transcriptionGO:19035072400.036
cellular catabolic processGO:00442483720.035
stem cell proliferationGO:0072089880.035
regulation of cell divisionGO:0051302720.034
purine ribonucleoside metabolic processGO:00461281270.034
appendage morphogenesisGO:00351073970.034
ribonucleotide catabolic processGO:00092611090.034
ribonucleoside catabolic processGO:00424541120.034
regulation of gene silencingGO:0060968630.034
intracellular signal transductionGO:00355563000.034
regulation of phosphorus metabolic processGO:00511742100.033
mitotic g2 dna damage checkpointGO:0007095690.032
protein processingGO:0016485680.032
regulation of microtubule cytoskeleton organizationGO:0070507410.032
negative regulation of biosynthetic processGO:00098902770.031
organelle localizationGO:00516401480.031
mitotic g2 m transition checkpointGO:0044818700.031
organonitrogen compound metabolic processGO:19015643180.031
positive regulation of mitotic cell cycleGO:0045931340.031
regulation of cell deathGO:00109411730.031
g1 s transition of mitotic cell cycleGO:0000082310.031
intracellular protein transportGO:00068861040.029
response to organic substanceGO:00100332840.029
ribonucleoside triphosphate catabolic processGO:00092031080.029
positive regulation of nucleic acid templated transcriptionGO:19035082660.028
centrosome cycleGO:00070981370.028
response to external biotic stimulusGO:00432072930.028
protein complex assemblyGO:00064612000.028
regulation of triglyceride catabolic processGO:001089610.027
regulation of proteasomal protein catabolic processGO:0061136390.027
developmental growthGO:00485892800.027
organophosphate metabolic processGO:00196371950.027
neuroblast divisionGO:0055057350.026
protein transportGO:00150311550.026
post embryonic appendage morphogenesisGO:00351203850.026
regulation of metaphase anaphase transition of cell cycleGO:1902099260.026
negative regulation of sister chromatid segregationGO:0033046130.025
mitotic spindle elongationGO:0000022810.025
dna damage checkpointGO:0000077780.025
cytoskeleton dependent cytokinesisGO:0061640810.025
positive regulation of cell cycleGO:0045787430.024
purine nucleoside triphosphate catabolic processGO:00091461080.024
negative regulation of stem cell proliferationGO:2000647300.024
gtp metabolic processGO:0046039720.024
cytokinesisGO:0000910900.024
phagocytosisGO:00069092150.024
regulation of cellular protein catabolic processGO:1903362440.023
cell cycle checkpointGO:0000075950.023
purine nucleotide metabolic processGO:00061631460.023
imaginal disc derived appendage developmentGO:00487373990.023
positive regulation of nucleobase containing compound metabolic processGO:00459353320.023
centrosome organizationGO:00512971630.023
locomotory behaviorGO:00076261760.022
posttranscriptional regulation of gene expressionGO:00106081450.022
nuclear migrationGO:0007097200.022
purine containing compound metabolic processGO:00725211550.022
leg disc developmentGO:0035218920.022
mitotic dna damage checkpointGO:0044773740.022
regulation of sister chromatid cohesionGO:000706320.022
small gtpase mediated signal transductionGO:0007264880.022
regulation of protein metabolic processGO:00512462560.021
appendage developmentGO:00487364010.021
response to biotic stimulusGO:00096072940.021
dna replicationGO:0006260480.021
nucleotide metabolic processGO:00091171610.021
positive regulation of immune system processGO:0002684680.021
nucleus organizationGO:0006997450.021
chromosome condensationGO:0030261410.021
regulation of catalytic activityGO:00507901850.020
single organism behaviorGO:00447083910.020
positive regulation of cellular catabolic processGO:0031331950.020
positive regulation of multicellular organismal processGO:00512401430.020
negative regulation of rna biosynthetic processGO:19026792400.020
regulation of protein processingGO:0070613320.020
regulation of neuron differentiationGO:00456641030.020
spindle assemblyGO:0051225800.020
regulation of cellular component biogenesisGO:00440872010.020
meiotic chromosome segregationGO:0045132590.019
nuclear body organizationGO:003057560.019
regulation of chromosome organizationGO:0033044640.019
histone mrna 3 end processingGO:000639880.019
regulation of molecular functionGO:00650092170.019
negative regulation of cell divisionGO:0051782170.019
ribonucleotide metabolic processGO:00092591450.019
rna processingGO:00063961470.019
proteolysis involved in cellular protein catabolic processGO:0051603830.018
negative regulation of response to stimulusGO:00485852580.018
heterocycle catabolic processGO:00467001660.018
regulation of neurogenesisGO:00507671580.018
nucleoside phosphate metabolic processGO:00067531620.018
purine nucleoside triphosphate metabolic processGO:00091441190.018
regulation of cellular catabolic processGO:00313291570.018
positive regulation of cell cycle processGO:0090068280.018
female meiotic divisionGO:0007143700.018
negative regulation of mitotic sister chromatid segregationGO:0033048130.018
cellular protein catabolic processGO:0044257830.018
mrna metabolic processGO:00160711240.018
regulation of dna metabolic processGO:0051052340.017
organophosphate catabolic processGO:00464341120.017
purine ribonucleotide metabolic processGO:00091501450.017
negative regulation of protein metabolic processGO:0051248850.017
genitalia developmentGO:0048806260.017
negative regulation of intracellular signal transductionGO:1902532570.017
nucleoside phosphate catabolic processGO:19012921100.017
negative regulation of cellular protein metabolic processGO:0032269850.017
phosphorylationGO:00163102940.017
negative regulation of cellular component organizationGO:00511291080.016
nucleoside triphosphate catabolic processGO:00091431080.016
nucleoside triphosphate metabolic processGO:00091411200.016
regulation of chromosome segregationGO:0051983320.016
regulation of cell cycle g1 s phase transitionGO:1902806230.016
positive regulation of catalytic activityGO:00430851180.016
proteolysisGO:00065081920.016
nucleocytoplasmic transportGO:0006913720.016
translationGO:0006412690.016
germ line cyst formationGO:0048134440.016
gene silencingGO:00164581380.016
gonad developmentGO:0008406500.016
positive regulation of biosynthetic processGO:00098913160.015
negative regulation of nitrogen compound metabolic processGO:00511722650.015
cell cycle dna replicationGO:0044786230.015
response to abiotic stimulusGO:00096283410.015
nucleobase containing small molecule metabolic processGO:00550861740.015
asymmetric protein localization involved in cell fate determinationGO:004516790.015
ion transportGO:00068111450.015
regulation of nucleoside metabolic processGO:0009118500.015
ras protein signal transductionGO:0007265880.015
regulation of g1 s transition of mitotic cell cycleGO:2000045230.015
mitotic nuclear divisionGO:00070672130.015
negative regulation of cell communicationGO:00106482230.015
positive regulation of developmental processGO:00510941430.015
positive regulation of cell developmentGO:0010720610.015
mitotic spindle checkpointGO:0071174110.015
dna packagingGO:0006323910.015
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.015
imaginal disc derived leg morphogenesisGO:0007480800.015
nucleotide catabolic processGO:00091661090.015
establishment of localization in cellGO:00516494020.015
negative regulation of proteolysisGO:0045861310.014
nuclear exportGO:0051168240.014
defense response to gram negative bacteriumGO:0050829940.014
single organism biosynthetic processGO:00447112060.014
purine ribonucleoside triphosphate catabolic processGO:00092071080.014
regulation of cytoskeleton organizationGO:0051493890.014
zymogen activationGO:0031638200.014
regulation of protein catabolic processGO:0042176550.014
modification dependent macromolecule catabolic processGO:0043632790.014
eye photoreceptor cell differentiationGO:00017541450.014
carbohydrate derivative catabolic processGO:19011361180.013
regulation of microtubule based processGO:0032886490.013
spindle assembly checkpointGO:0071173110.013
development of primary sexual characteristicsGO:0045137500.013
negative regulation of transcription dna templatedGO:00458922370.013
regulation of proteolysisGO:0030162870.013
response to other organismGO:00517072930.013
protein complex biogenesisGO:00702712010.013
negative regulation of cell deathGO:0060548810.013
positive regulation of molecular functionGO:00440931360.013
regulation of catabolic processGO:00098941700.013
positive regulation of phosphorus metabolic processGO:00105621390.013
rna localizationGO:00064031150.013
response to copper ionGO:004668840.012
reproductive structure developmentGO:0048608740.012
single organism catabolic processGO:00447122280.012
positive regulation of mitotic cell cycle phase transitionGO:1901992200.012
regulation of transcription from rna polymerase ii promoterGO:00063573780.012
response to uvGO:0009411240.012
protein localization to organelleGO:0033365820.012
purine ribonucleotide catabolic processGO:00091541090.012
purine nucleoside catabolic processGO:00061521120.012
nucleobase containing compound catabolic processGO:00346551650.012
olfactory learningGO:0008355560.012
nuclear dna replicationGO:003326010.012
female germ line cyst formationGO:0048135420.012
brain developmentGO:00074201200.012
regulation of innate immune responseGO:0045088710.012
nucleoside catabolic processGO:00091641120.012
negative regulation of proteasomal protein catabolic processGO:1901799160.012
establishment of nucleus localizationGO:0040023260.011
regulation of sister chromatid segregationGO:0033045280.011
establishment of protein localizationGO:00451841630.011
embryo development ending in birth or egg hatchingGO:00097921520.011
regulation of cell projection organizationGO:0031344920.011
establishment of organelle localizationGO:00516561220.011
positive regulation of neurogenesisGO:0050769410.011
nuclear divisionGO:00002803320.011
nucleoside metabolic processGO:00091161270.011
chromatin assembly or disassemblyGO:0006333520.011
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145300.011
atp dependent chromatin remodelingGO:0043044220.011
ribose phosphate metabolic processGO:00196931450.011
regulation of hemocyte proliferationGO:0035206370.011
sister chromatid segregationGO:0000819920.011
regulation of ras protein signal transductionGO:0046578930.011
meiotic dna double strand break formationGO:004213810.011
positive regulation of cell differentiationGO:0045597640.011
centrosome duplicationGO:00512981210.011
regulation of gene expression epigeneticGO:00400291280.011
mitotic spindle assembly checkpointGO:0007094110.010
negative regulation of multicellular organismal processGO:00512411420.010
mrna 3 end processingGO:0031124280.010
defense response to bacteriumGO:00427421780.010
response to woundingGO:0009611940.010

mad2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.024
disease of cellular proliferationDOID:1456600.018
cancerDOID:16200.018
nervous system diseaseDOID:86300.011