Drosophila melanogaster

42 known processes

alpha-Cat (Dmel_CG17947)

alpha Catenin

(Aliases: alphaCat,alpha-ctn,Dalpha-catenin,Dalpha-cat,a-cat,alpha-CAT,CT39986,alphaCAT,alphacat,Dmcatp,DalphaC,Dalphacat,Dmel\CG17947,Dalpha-Cat,alpha-cat,CG17947,a-Cat)

alpha-Cat biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
ovarian follicle cell developmentGO:00307072480.999
germarium derived egg chamber formationGO:00072931010.998
epithelial cell differentiationGO:00308553220.996
germ line cyst formationGO:0048134440.995
ovarian follicle cell migrationGO:00072971210.994
columnar cuboidal epithelial cell differentiationGO:00020652560.993
epithelial cell developmentGO:00020642740.990
epithelial cell migrationGO:00106311480.988
female germ line cyst formationGO:0048135420.979
germarium derived female germ line cyst formationGO:0030727420.975
border follicle cell migrationGO:00072981130.963
localization of cellGO:00516742570.959
columnar cuboidal epithelial cell developmentGO:00020662490.938
cell migrationGO:00164772380.923
tissue migrationGO:00901301550.878
epithelium migrationGO:00901321480.876
programmed cell deathGO:00125012570.860
cell deathGO:00082192790.771
regulation of programmed cell deathGO:00430671520.767
cell motilityGO:00488702510.716
urogenital system developmentGO:0001655720.697
cell proliferationGO:00082832990.604
ameboidal type cell migrationGO:00016671510.575
immune system processGO:00023763470.569
deathGO:00162652840.568
endocytosisGO:00068973100.560
Fly
negative regulation of developmental processGO:00510932010.512
larval developmentGO:00021641040.511
regulation of multicellular organismal developmentGO:20000264140.497
response to starvationGO:0042594970.476
apoptotic processGO:00069151590.467
sex differentiationGO:0007548810.412
Rat
chromosome segregationGO:00070591570.380
embryonic development via the syncytial blastodermGO:00017001480.380
embryo development ending in birth or egg hatchingGO:00097921520.376
cell projection assemblyGO:0030031940.372
meiotic cell cycleGO:00513211710.372
actin filament based processGO:00300292200.358
mrna metabolic processGO:00160711240.348
organic substance catabolic processGO:19015753080.346
regulation of cell shapeGO:00083601130.345
development of primary sexual characteristicsGO:0045137500.337
Rat
actin cytoskeleton organizationGO:00300362060.324
negative regulation of rna metabolic processGO:00512532510.316
negative regulation of cellular metabolic processGO:00313243820.314
multi organism behaviorGO:00517051750.305
reproductive behaviorGO:00190981220.288
axis specificationGO:00097981670.287
blastoderm segmentationGO:00073501590.282
regulation of cellular component biogenesisGO:00440872010.265
anterior posterior pattern specificationGO:00099521360.264
nucleobase containing compound catabolic processGO:00346551650.241
meiotic chromosome segregationGO:0045132590.239
negative regulation of gene expressionGO:00106293870.228
response to abiotic stimulusGO:00096283410.215
single organism behaviorGO:00447083910.211
establishment of nucleus localizationGO:0040023260.208
regulation of notch signaling pathwayGO:00085931000.195
establishment or maintenance of cell polarityGO:00071631670.185
eggshell formationGO:00307031050.183
meiotic nuclear divisionGO:00071261510.175
positive regulation of nucleobase containing compound metabolic processGO:00459353320.172
segmentationGO:00352822070.166
nuclear divisionGO:00002803320.159
regulation of actin filament based processGO:0032970420.154
organic cyclic compound catabolic processGO:19013611680.151
regulation of cell deathGO:00109411730.149
macromolecular complex assemblyGO:00650032560.143
Rat
nucleus localizationGO:0051647340.143
covalent chromatin modificationGO:00165691060.142
biological adhesionGO:00226101380.142
Human Mouse
cellular catabolic processGO:00442483720.140
actin filament based movementGO:0030048260.138
compound eye developmentGO:00487493070.133
multi multicellular organism processGO:00447061230.132
organonitrogen compound metabolic processGO:19015643180.129
oocyte axis specificationGO:00073091080.128
embryonic pattern specificationGO:00098801740.120
regionalizationGO:00030024160.117
asymmetric protein localization involved in cell fate determinationGO:004516790.116
regulation of organelle organizationGO:00330431960.114
regulation of cell morphogenesisGO:00226041630.110
cellular macromolecule catabolic processGO:00442651360.109
maintenance of locationGO:0051235730.107
cleavage furrow formationGO:003608920.106
developmental growthGO:00485892800.104
regulation of anatomical structure morphogenesisGO:00226032420.102
pigmentationGO:0043473750.099
cellular macromolecular complex assemblyGO:00346221530.098
negative regulation of signalingGO:00230572190.097
catabolic processGO:00090564090.095
oocyte developmentGO:00485991240.095
digestive tract developmentGO:00485651490.093
multi organism reproductive behaviorGO:00447051210.092
ras protein signal transductionGO:0007265880.088
growthGO:00400073590.087
axon developmentGO:00615642970.086
Rat
formation of a compartment boundaryGO:006028840.086
nucleoside phosphate metabolic processGO:00067531620.086
asymmetric protein localizationGO:0008105330.085
regulation of transportGO:00510491810.085
negative regulation of cell communicationGO:00106482230.084
tripartite regional subdivisionGO:00073511030.082
negative regulation of nitrogen compound metabolic processGO:00511722650.082
axonogenesisGO:00074092900.081
oocyte differentiationGO:00099941450.079
chromosome organizationGO:00512763600.079
reproductive system developmentGO:0061458740.077
Rat
heterocycle catabolic processGO:00467001660.076
cellular nitrogen compound catabolic processGO:00442701650.073
positive regulation of phosphorus metabolic processGO:00105621390.073
cellular response to chemical stimulusGO:00708871990.071
meiotic cell cycle processGO:19030461320.070
notch signaling pathwayGO:00072191200.069
eye developmentGO:00016543230.066
small molecule metabolic processGO:00442813050.066
small gtpase mediated signal transductionGO:0007264880.066
negative regulation of protein secretionGO:005070920.064
anterior posterior axis specification embryoGO:00085951030.064
renal tubule developmentGO:0061326640.064
regulation of transcription from rna polymerase ii promoterGO:00063573780.064
multicellular organismal reproductive behaviorGO:00330571100.064
regulation of endocytosisGO:0030100370.063
positive regulation of nitrogen compound metabolic processGO:00511733540.063
morphogenesis of embryonic epitheliumGO:0016331940.062
macromolecule catabolic processGO:00090571610.061
purine ribonucleotide metabolic processGO:00091501450.061
regulation of phosphorus metabolic processGO:00511742100.060
guanosine containing compound catabolic processGO:1901069740.060
positive regulation of rna metabolic processGO:00512542710.060
organelle fissionGO:00482853400.059
morphogenesis of an epitheliumGO:00020092760.058
cell adhesionGO:00071551360.058
Human Mouse
protein modification processGO:00362114380.057
negative regulation of necrotic cell deathGO:006054710.057
regulation of protein complex assemblyGO:0043254420.055
aromatic compound catabolic processGO:00194391660.053
head developmentGO:00603221350.053
negative regulation of cell developmentGO:0010721620.053
regulation of catalytic activityGO:00507901850.052
protein complex biogenesisGO:00702712010.052
Rat
regulation of apoptotic processGO:00429811300.050
purine nucleoside metabolic processGO:00422781270.050
positive regulation of ribosome biogenesisGO:009007030.050
maintenance of protein location in cellGO:0032507260.049
regulation of protein polymerizationGO:0032271280.049
regulation of cell cycle processGO:00105641810.048
meiotic nuclear envelope disassemblyGO:005107820.048
negative regulation of cell differentiationGO:00455961430.047
positive regulation of cellular component organizationGO:00511301560.047
positive regulation of signalingGO:00230562430.046
positive regulation of phosphate metabolic processGO:00459371390.046
rna splicingGO:0008380830.046
regulation of cellular catabolic processGO:00313291570.045
body morphogenesisGO:001017120.045
immune effector processGO:0002252980.044
regulation of cellular component sizeGO:0032535980.044
glycosyl compound metabolic processGO:19016571270.044
developmental programmed cell deathGO:00106231380.044
regulation of cell developmentGO:00602842150.043
actin filament polymerizationGO:0030041270.043
kidney developmentGO:000182230.042
brain developmentGO:00074201200.042
anterior posterior axis specificationGO:00099481090.042
regulation of actin filament lengthGO:0030832270.041
regulation of hemocyte proliferationGO:0035206370.041
organelle localizationGO:00516401480.041
regulation of catabolic processGO:00098941700.040
positive regulation of transcription dna templatedGO:00458932660.040
camera type eye developmentGO:004301040.040
negative regulation of nucleobase containing compound metabolic processGO:00459342610.040
immune responseGO:00069552460.040
phagocytosisGO:00069092150.039
Fly
negative regulation of nervous system developmentGO:0051961920.039
negative regulation of signal transductionGO:00099682060.039
intracellular signal transductionGO:00355563000.039
regulation of cell projection organizationGO:0031344920.038
cytoskeleton dependent cytokinesisGO:0061640810.038
regulation of ras gtpase activityGO:0032318380.038
positive regulation of cellular biosynthetic processGO:00313283160.038
organophosphate metabolic processGO:00196371950.038
negative regulation of cellular biosynthetic processGO:00313272770.037
vesicle mediated transportGO:00161923810.037
Fly
negative regulation of response to stimulusGO:00485852580.036
mrna processingGO:00063971040.036
positive regulation of catabolic processGO:00098961050.036
reproductive structure developmentGO:0048608740.036
Rat
positive regulation of cellular catabolic processGO:0031331950.035
spindle organizationGO:00070512530.035
actin filament organizationGO:00070151260.035
positive regulation of cell communicationGO:00106472500.034
amine metabolic processGO:0009308120.033
protein localizationGO:00081042840.033
cellular ketone metabolic processGO:0042180240.033
regulation of protein modification processGO:00313991120.033
regulation of striated muscle contractionGO:000694220.032
regulation of hydrolase activityGO:0051336970.032
regulation of nucleotide catabolic processGO:0030811480.032
negative regulation of cellular component organizationGO:00511291080.032
negative regulation of nurse cell apoptotic processGO:004584920.032
renal system developmentGO:0072001720.031
regulation of vesicle mediated transportGO:0060627590.031
positive regulation of response to stimulusGO:00485843230.031
single organism catabolic processGO:00447122280.031
purine ribonucleoside metabolic processGO:00461281270.031
peptidyl amino acid modificationGO:00181931050.031
locomotory behaviorGO:00076261760.030
positive regulation of signal transductionGO:00099672230.030
sensory organ morphogenesisGO:00905962600.030
endosomal vesicle fusionGO:003405840.030
establishment of localization in cellGO:00516494020.030
purine containing compound metabolic processGO:00725211550.030
intracellular transportGO:00469072280.029
cellular component disassemblyGO:0022411460.029
nitric oxide metabolic processGO:004620910.029
cell cycle arrestGO:000705040.029
neurological system processGO:00508773580.029
cell divisionGO:00513012480.029
peptidyl lysine acetylationGO:0018394390.029
regulation of growthGO:00400082330.029
rac protein signal transductionGO:001660130.029
carboxylic acid metabolic processGO:0019752920.028
negative regulation of transcription dna templatedGO:00458922370.028
chorion containing eggshell formationGO:00073041050.028
carbohydrate derivative metabolic processGO:19011352170.028
regulation of actin filament polymerizationGO:0030833250.027
dna integrationGO:001507410.027
central nervous system developmentGO:00074172010.027
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.026
mitotic dna integrity checkpointGO:0044774750.026
single organism intracellular transportGO:19025822070.025
humoral immune responseGO:00069591170.025
renal tubule morphogenesisGO:0061333440.025
cell fate specificationGO:0001708710.024
establishment of protein localizationGO:00451841630.024
regulation of purine nucleotide catabolic processGO:0033121480.023
negative regulation of rna biosynthetic processGO:19026792400.023
positive regulation of hydrolase activityGO:0051345780.023
regulation of cell differentiationGO:00455953020.023
female meiotic divisionGO:0007143700.023
positive regulation of molecular functionGO:00440931360.022
hindbrain developmentGO:003090220.022
regulation of molecular functionGO:00650092170.022
regulation of protein phosphorylationGO:0001932640.022
regulation of anatomical structure sizeGO:00900661630.022
negative regulation of biosynthetic processGO:00098902770.022
oocyte morphogenesisGO:004860130.022
stem cell differentiationGO:00488631170.022
determination of adult lifespanGO:00083401370.022
malpighian tubule developmentGO:0072002640.022
mitochondrial membrane organizationGO:000700630.022
developmental maturationGO:00217001720.021
organophosphate catabolic processGO:00464341120.021
pigment metabolic processGO:0042440840.021
regulation of nucleotide metabolic processGO:0006140620.021
hematopoietic or lymphoid organ developmentGO:0048534570.021
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.021
cellular protein localizationGO:00346131600.021
positive regulation of neuron projection regenerationGO:007057230.020
regulation of cellular amino acid metabolic processGO:000652100.020
eye morphogenesisGO:00485922600.020
cellular protein complex assemblyGO:0043623710.020
negative regulation of protein bindingGO:003209110.020
ribonucleoside metabolic processGO:00091191270.020
regulation of protein kinase activityGO:0045859510.020
enzyme linked receptor protein signaling pathwayGO:00071671790.020
protein polymerizationGO:0051258420.019
nucleotide metabolic processGO:00091171610.019
ribonucleoside triphosphate catabolic processGO:00092031080.019
morphogenesis of follicular epitheliumGO:0016333360.019
agingGO:00075681430.019
Rat
establishment or maintenance of cytoskeleton polarityGO:0030952440.019
gonad developmentGO:0008406500.019
Rat
regulation of actin polymerization or depolymerizationGO:0008064270.019
regulation of nucleoside metabolic processGO:0009118500.019
gtp metabolic processGO:0046039720.019
single organism cellular localizationGO:19025801800.018
regulation of phosphate metabolic processGO:00192202100.018
negative regulation of cellular protein metabolic processGO:0032269850.018
genitalia developmentGO:0048806260.018
eye photoreceptor cell developmentGO:0042462810.018
purine containing compound catabolic processGO:00725231120.018
positive regulation of cell cycle processGO:0090068280.018
nuclear migrationGO:0007097200.018
neuron projection guidanceGO:00974852410.018
cytokinesisGO:0000910900.018
lipid storageGO:0019915380.018
oocyte nucleus localization involved in oocyte dorsal ventral axis specificationGO:0051663120.018
regulation of ras protein signal transductionGO:0046578930.018
response to oxygen containing compoundGO:19017002000.018
positive regulation of purine nucleotide catabolic processGO:0033123460.018
regulation of reactive oxygen species biosynthetic processGO:190342600.018
negative regulation of terminal cell fate specification open tracheal systemGO:003515520.018
rna processingGO:00063961470.018
regulation of phosphatase activityGO:001092130.017
positive regulation of transportGO:0051050920.017
gland developmentGO:00487321910.017
mapk import into nucleusGO:000018910.017
rna localizationGO:00064031150.017
regulation of cellular protein metabolic processGO:00322682430.017
positive regulation of catalytic activityGO:00430851180.016
gland morphogenesisGO:00226121450.016
nucleoside catabolic processGO:00091641120.016
nucleoside triphosphate metabolic processGO:00091411200.016
regulation of multi organism processGO:00439001310.016
imaginal disc derived wing morphogenesisGO:00074763370.016
positive regulation of cellular component biogenesisGO:0044089800.016
positive regulation of gtpase activityGO:0043547430.016
regulation of embryonic developmentGO:0045995680.016
purine nucleoside catabolic processGO:00061521120.015
positive regulation of nucleotide catabolic processGO:0030813460.015
response to nutrient levelsGO:00316671140.015
mitotic spindle organizationGO:00070522200.015
nucleotide catabolic processGO:00091661090.015
positive regulation of developmental processGO:00510941430.015
cortical actin cytoskeleton organizationGO:0030866240.015
epithelial cell morphogenesis involved in gastrulationGO:000338170.015
maternal determination of dorsal ventral axis ovarian follicular epithelium soma encodedGO:000807110.015
positive regulation of cell maturationGO:190343120.015
regulation of protein localizationGO:0032880760.015
ribonucleoside catabolic processGO:00424541120.015
positive regulation of programmed cell deathGO:0043068620.015
protein transportGO:00150311550.015
transcription from rna polymerase ii promoterGO:00063663680.015
regulation of epidermal growth factor receptor signaling pathwayGO:0042058420.015
tissue morphogenesisGO:00487292970.015
regulation of cell projection assemblyGO:0060491300.015
nucleoside metabolic processGO:00091161270.014
dendrite regenerationGO:003110420.014
regulation of signal transduction by p53 class mediatorGO:190179610.014
regulation of transferase activityGO:0051338580.014
compound eye morphogenesisGO:00017452490.014
negative regulation of macromolecule biosynthetic processGO:00105582700.014
regulation of cyclin dependent protein serine threonine kinase activityGO:000007930.014
regulation of actin cytoskeleton organizationGO:0032956420.014
oocyte constructionGO:00073081120.014
positive regulation of intracellular signal transductionGO:19025331160.014
ribonucleoside triphosphate metabolic processGO:00091991190.014
regulation of gene expression epigeneticGO:00400291280.014
retina development in camera type eyeGO:006004140.014
signal transduction in response to dna damageGO:004277030.014
negative regulation of cell cycleGO:00457861160.013
nucleoside phosphate catabolic processGO:19012921100.013
wound healingGO:0042060750.013
negative regulation of cell deathGO:0060548810.013
immune system developmentGO:0002520570.013
regulation of nervous system developmentGO:00519602480.013
protein phosphorylationGO:00064681690.013
response to extracellular stimulusGO:00099911160.013
regulation of cell cycleGO:00517262910.013
wnt signaling pathwayGO:0016055980.013
positive regulation of nucleotide metabolic processGO:0045981550.012
regulation of synaptic transmissionGO:0050804690.012
regulation of immune system processGO:00026821760.012
signal transduction by phosphorylationGO:00230141070.012
activation of ral gtpase activityGO:003285910.012
oocyte fate commitmentGO:004860020.012
regulation of protein metabolic processGO:00512462560.012
positive regulation of purine nucleotide metabolic processGO:1900544550.012
regulation of small gtpase mediated signal transductionGO:0051056930.012
isoprenoid biosynthetic processGO:000829930.012
regulation of compound eye retinal cell programmed cell deathGO:0046669180.012
purine nucleoside triphosphate catabolic processGO:00091461080.012
regulation of localizationGO:00328792750.012
regulation of neurogenesisGO:00507671580.012
ribose phosphate metabolic processGO:00196931450.012
purine nucleoside triphosphate metabolic processGO:00091441190.012
negative regulation of transcription from rna polymerase iii promoterGO:001648020.012
cellular macromolecule localizationGO:00707272200.012
meiotic spindle checkpointGO:004477910.012
positive regulation of defense responseGO:0031349590.012
lipid localizationGO:0010876540.012
synapse organizationGO:00508081960.012
salivary gland histolysisGO:0035070880.012
protein localization to organelleGO:0033365820.011
epithelial tube morphogenesisGO:0060562880.011
unidimensional cell growthGO:0009826150.011
nucleocytoplasmic transportGO:0006913720.011
cuticle developmentGO:0042335860.011
cellular amine metabolic processGO:0044106120.011
regulation of organ morphogenesisGO:2000027780.011
regulation of purine nucleotide metabolic processGO:1900542620.011
negative regulation of phosphatase activityGO:001092330.011
purine ribonucleotide catabolic processGO:00091541090.011
purine nucleotide metabolic processGO:00061631460.011
sirna loading onto risc involved in rna interferenceGO:003508740.011
oxoacid metabolic processGO:00434361030.011
establishment of protein localization to organelleGO:0072594620.011
juvenile hormone mediated signaling pathwayGO:003562630.011
purine nucleoside monophosphate catabolic processGO:0009128380.011
embryonic axis specificationGO:00005781070.011
mitotic cell cycle phase transitionGO:00447721380.010
regulation of cellular ketone metabolic processGO:001056530.010
negative regulation of intrinsic apoptotic signaling pathwayGO:200124310.010
mapk cascadeGO:00001651070.010
membrane organizationGO:00610241120.010
organelle assemblyGO:00709251980.010
cell maturationGO:00484691440.010
dna endoreduplicationGO:0042023220.010
eye antennal disc developmentGO:0035214600.010
regulation of embryonic cell shapeGO:0016476300.010
anterior posterior axis specification follicular epitheliumGO:003071420.010
regulation of erbb signaling pathwayGO:1901184420.010
axon guidanceGO:00074112330.010

alpha-Cat disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
syndromeDOID:22500.025
disease of anatomical entityDOID:700.022
Human
nervous system diseaseDOID:86300.019
gonadal dysgenesisDOID:1444700.016
chromosomal diseaseDOID:008001400.016
aortic diseaseDOID:52000.016
aortic aneurysmDOID:362700.016
vascular diseaseDOID:17800.016
artery diseaseDOID:005082800.016
cardiovascular system diseaseDOID:128700.016
Human
endocrine gland cancerDOID:17000.010
disease of cellular proliferationDOID:1456600.010
organ system cancerDOID:005068600.010
thyroid cancerDOID:178100.010
cancerDOID:16200.010