Drosophila melanogaster

24 known processes

mib2 (Dmel_CG17492)

mind bomb 2

(Aliases: Be,suelto,Dmel\CG17492,D-mibl,l(2)37Be,CG17492,i115)

mib2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
myoblast fusionGO:0007520430.863
adult behaviorGO:00305341370.463
muscle cell differentiationGO:00426921030.444
negative regulation of gene expressionGO:00106293870.436
striated muscle cell differentiationGO:0051146900.432
actin filament based processGO:00300292200.304
deathGO:00162652840.276
regulation of cellular component biogenesisGO:00440872010.267
muscle structure developmentGO:00610612240.251
negative regulation of rna biosynthetic processGO:19026792400.251
purine nucleoside metabolic processGO:00422781270.250
regulation of intracellular signal transductionGO:19025312360.225
Human
endocytosisGO:00068973100.223
Fly
protein complex assemblyGO:00064612000.220
purine ribonucleoside catabolic processGO:00461301120.219
negative regulation of biosynthetic processGO:00098902770.209
myotube differentiationGO:0014902460.192
establishment of localization in cellGO:00516494020.191
positive regulation of nucleic acid templated transcriptionGO:19035082660.189
wing disc morphogenesisGO:00074723440.180
Fly
cellular component disassemblyGO:0022411460.174
actin cytoskeleton organizationGO:00300362060.169
syncytium formation by plasma membrane fusionGO:0000768430.166
embryo development ending in birth or egg hatchingGO:00097921520.149
nucleoside triphosphate catabolic processGO:00091431080.142
organelle assemblyGO:00709251980.140
somatic muscle developmentGO:0007525660.138
protein localizationGO:00081042840.134
Fly
nucleoside triphosphate metabolic processGO:00091411200.129
ribose phosphate metabolic processGO:00196931450.126
macromolecular complex assemblyGO:00650032560.124
negative regulation of nucleobase containing compound metabolic processGO:00459342610.123
purine ribonucleoside metabolic processGO:00461281270.123
protein modification by small protein conjugation or removalGO:00706471060.120
Mouse Fly
purine nucleotide catabolic processGO:00061951090.119
organonitrogen compound metabolic processGO:19015643180.115
syncytium formationGO:0006949430.112
carbohydrate derivative catabolic processGO:19011361180.110
aromatic compound catabolic processGO:00194391660.108
intracellular signal transductionGO:00355563000.108
Human
regulation of organelle organizationGO:00330431960.108
secretion by cellGO:00329401010.106
positive regulation of molecular functionGO:00440931360.106
negative regulation of microtubule polymerization or depolymerizationGO:0031111210.104
positive regulation of cellular biosynthetic processGO:00313283160.104
ribonucleoside metabolic processGO:00091191270.103
positive regulation of biosynthetic processGO:00098913160.102
positive regulation of rna metabolic processGO:00512542710.100
regulation of molecular functionGO:00650092170.100
actin filament organizationGO:00070151260.100
locomotory behaviorGO:00076261760.100
regulation of transcription from rna polymerase ii promoterGO:00063573780.099
proteolysisGO:00065081920.098
protein modification processGO:00362114380.097
Mouse Fly
protein complex biogenesisGO:00702712010.097
chromosome segregationGO:00070591570.094
ribonucleoside catabolic processGO:00424541120.092
purine nucleoside catabolic processGO:00061521120.090
positive regulation of transcription dna templatedGO:00458932660.090
purine ribonucleoside triphosphate catabolic processGO:00092071080.090
negative regulation of cellular metabolic processGO:00313243820.089
purine ribonucleoside triphosphate metabolic processGO:00092051190.084
nucleotide metabolic processGO:00091171610.084
purine ribonucleotide catabolic processGO:00091541090.083
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.082
regulation of hydrolase activityGO:0051336970.080
regulation of cytoskeleton organizationGO:0051493890.080
purine ribonucleotide metabolic processGO:00091501450.080
cellular catabolic processGO:00442483720.078
intracellular transportGO:00469072280.076
negative regulation of signalingGO:00230572190.075
positive regulation of signalingGO:00230562430.074
Human Fly
response to light stimulusGO:00094161240.074
small gtpase mediated signal transductionGO:0007264880.074
purine nucleoside triphosphate metabolic processGO:00091441190.073
small molecule metabolic processGO:00442813050.073
positive regulation of developmental processGO:00510941430.072
homeostatic processGO:00425921990.071
glycosyl compound catabolic processGO:19016581120.069
organic substance transportGO:00717022570.068
regionalizationGO:00030024160.067
cellular protein modification processGO:00064644380.067
Mouse Fly
heterocycle catabolic processGO:00467001660.067
ras protein signal transductionGO:0007265880.067
cellular protein complex assemblyGO:0043623710.066
positive regulation of cell communicationGO:00106472500.064
Human Fly
embryonic pattern specificationGO:00098801740.063
positive regulation of cellular component organizationGO:00511301560.063
organelle fissionGO:00482853400.063
ribonucleoside triphosphate catabolic processGO:00092031080.060
organophosphate catabolic processGO:00464341120.060
negative regulation of macromolecule biosynthetic processGO:00105582700.059
regulation of cell shapeGO:00083601130.058
carbohydrate derivative metabolic processGO:19011352170.057
regulation of nucleoside metabolic processGO:0009118500.056
positive regulation of response to stimulusGO:00485843230.055
Human Fly
cellular nitrogen compound catabolic processGO:00442701650.055
regulation of small gtpase mediated signal transductionGO:0051056930.055
single organism behaviorGO:00447083910.054
imaginal disc derived wing morphogenesisGO:00074763370.054
Fly
carbohydrate metabolic processGO:0005975820.054
positive regulation of nitrogen compound metabolic processGO:00511733540.053
regulation of multicellular organismal developmentGO:20000264140.053
ribonucleotide catabolic processGO:00092611090.052
nucleotide catabolic processGO:00091661090.052
vesicle mediated transportGO:00161923810.052
Fly
regulation of catalytic activityGO:00507901850.052
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.052
regulation of cellular catabolic processGO:00313291570.052
cellular macromolecule catabolic processGO:00442651360.052
establishment or maintenance of microtubule cytoskeleton polarityGO:0030951410.052
imaginal disc derived appendage developmentGO:00487373990.051
Fly
positive regulation of phosphorus metabolic processGO:00105621390.051
nucleoside catabolic processGO:00091641120.051
macromolecular complex disassemblyGO:0032984370.051
axon developmentGO:00615642970.051
glycosyl compound metabolic processGO:19016571270.048
positive regulation of rna biosynthetic processGO:19026802660.048
protein polymerizationGO:0051258420.048
body morphogenesisGO:001017120.048
sperm mitochondrion organizationGO:003038270.048
response to temperature stimulusGO:00092661060.047
positive regulation of macromolecule metabolic processGO:00106044050.047
negative regulation of cellular biosynthetic processGO:00313272770.046
flight behaviorGO:0007629260.046
epithelial cell developmentGO:00020642740.046
single organism carbohydrate metabolic processGO:0044723720.045
mapk cascadeGO:00001651070.044
regulation of notch signaling pathwayGO:00085931000.044
Fly
protein depolymerizationGO:0051261310.044
nucleoside phosphate metabolic processGO:00067531620.044
positive regulation of macromolecule biosynthetic processGO:00105572830.044
protein modification by small protein conjugationGO:0032446790.042
Mouse Fly
cytokinesisGO:0000910900.042
sister chromatid segregationGO:0000819920.042
cell motilityGO:00488702510.042
positive regulation of erk1 and erk2 cascadeGO:0070374360.041
regulation of ras protein signal transductionGO:0046578930.041
positive regulation of signal transductionGO:00099672230.041
Human Fly
axonogenesisGO:00074092900.041
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.041
larval developmentGO:00021641040.041
purine containing compound metabolic processGO:00725211550.040
ribonucleoside triphosphate metabolic processGO:00091991190.040
positive regulation of nucleobase containing compound metabolic processGO:00459353320.040
nucleobase containing compound catabolic processGO:00346551650.040
positive regulation of hydrolase activityGO:0051345780.039
rrna processingGO:000636430.039
negative regulation of response to stimulusGO:00485852580.038
epithelial cell differentiationGO:00308553220.038
cellular protein complex disassemblyGO:0043624350.038
blastoderm segmentationGO:00073501590.038
positive regulation of cell differentiationGO:0045597640.037
modification dependent macromolecule catabolic processGO:0043632790.037
catabolic processGO:00090564090.036
guanosine containing compound catabolic processGO:1901069740.036
atp metabolic processGO:0046034490.036
chromosome organizationGO:00512763600.035
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.035
post embryonic appendage morphogenesisGO:00351203850.035
Fly
organic substance catabolic processGO:19015753080.035
organonitrogen compound catabolic processGO:19015651280.034
organophosphate metabolic processGO:00196371950.034
enzyme linked receptor protein signaling pathwayGO:00071671790.033
regulation of protein metabolic processGO:00512462560.033
response to external biotic stimulusGO:00432072930.033
nucleoside metabolic processGO:00091161270.033
regulation of actin filament lengthGO:0030832270.033
ribonucleotide metabolic processGO:00092591450.033
cellular component assembly involved in morphogenesisGO:00109271510.033
organic acid metabolic processGO:00060821030.033
cell deathGO:00082192790.032
purine nucleotide metabolic processGO:00061631460.032
localization of cellGO:00516742570.032
purine ribonucleoside monophosphate metabolic processGO:0009167500.032
regulation of actin cytoskeleton organizationGO:0032956420.032
striated muscle myosin thick filament assemblyGO:007168830.031
positive regulation of cellular amino acid metabolic processGO:004576400.031
negative regulation of organelle organizationGO:0010639560.031
columnar cuboidal epithelial cell differentiationGO:00020652560.031
dna metabolic processGO:00062592270.030
cellular macromolecular complex assemblyGO:00346221530.030
positive regulation of cellular component biogenesisGO:0044089800.030
positive regulation of phosphate metabolic processGO:00459371390.030
proteasomal protein catabolic processGO:0010498590.030
single organism intracellular transportGO:19025822070.030
protein transportGO:00150311550.029
purine containing compound catabolic processGO:00725231120.029
vesicle organizationGO:0016050440.029
purine nucleoside monophosphate metabolic processGO:0009126500.029
programmed cell deathGO:00125012570.029
positive regulation of catabolic processGO:00098961050.028
regulation of phosphorus metabolic processGO:00511742100.028
positive regulation of multicellular organismal processGO:00512401430.028
transcription from rna polymerase ii promoterGO:00063663680.028
response to organic substanceGO:00100332840.028
regulation of mitochondrial fusionGO:001063550.028
regulation of actin filament based processGO:0032970420.027
negative regulation of signal transductionGO:00099682060.027
rna localizationGO:00064031150.027
regulation of cell deathGO:00109411730.027
phosphorylationGO:00163102940.027
ubiquitin dependent protein catabolic processGO:0006511780.027
modification dependent protein catabolic processGO:0019941780.027
response to extracellular stimulusGO:00099911160.027
developmental programmed cell deathGO:00106231380.026
secretionGO:00469031090.026
regulation of synapse structure and activityGO:00508031280.026
regulation of cellular localizationGO:00603411360.026
notch signaling pathwayGO:00072191200.026
Fly
positive regulation of mapk cascadeGO:0043410630.025
positive regulation of gene expressionGO:00106282900.025
positive regulation of intracellular signal transductionGO:19025331160.025
Human
regulation of purine nucleotide catabolic processGO:0033121480.025
detection of abiotic stimulusGO:0009582660.025
negative regulation of nucleic acid templated transcriptionGO:19035072400.025
defense responseGO:00069523000.025
centrosome cycleGO:00070981370.025
purine nucleoside triphosphate catabolic processGO:00091461080.025
negative regulation of cell communicationGO:00106482230.024
embryonic development via the syncytial blastodermGO:00017001480.024
phagocytosisGO:00069092150.024
regulation of mitochondrial fissionGO:009014070.024
positive regulation of cell developmentGO:0010720610.024
larval somatic muscle developmentGO:0007526190.024
ovarian follicle cell migrationGO:00072971210.024
regulation of phosphate metabolic processGO:00192202100.024
regulation of proteolysisGO:0030162870.024
mitotic spindle organizationGO:00070522200.024
ribonucleoside monophosphate catabolic processGO:0009158390.023
stem cell differentiationGO:00488631170.023
erbb signaling pathwayGO:0038127580.023
regulation of cellular amine metabolic processGO:003323830.023
membrane buddingGO:000690040.023
chaeta developmentGO:0022416970.023
cellular macromolecule localizationGO:00707272200.023
regulation of erbb signaling pathwayGO:1901184420.022
myofibril assemblyGO:0030239360.022
sarcomere organizationGO:0045214260.022
detection of external stimulusGO:0009581660.022
regulation of transportGO:00510491810.022
inositol lipid mediated signalingGO:004801740.022
proteolysis involved in cellular protein catabolic processGO:0051603830.022
cytoskeleton dependent cytokinesisGO:0061640810.022
nucleoside monophosphate metabolic processGO:0009123520.022
intracellular protein transportGO:00068861040.022
mitochondrial fusionGO:000805370.022
protein complex disassemblyGO:0043241360.022
skeletal muscle organ developmentGO:0060538480.022
regulation of microtubule polymerization or depolymerizationGO:0031110270.021
nucleoside phosphate catabolic processGO:19012921100.021
negative regulation of cytoskeleton organizationGO:0051494300.021
regulation of actin polymerization or depolymerizationGO:0008064270.021
intracellular mrna localization involved in anterior posterior axis specificationGO:0060811530.021
compound eye developmentGO:00487493070.020
Fly
organic cyclic compound catabolic processGO:19013611680.020
single organism catabolic processGO:00447122280.020
regulation of nucleotide catabolic processGO:0030811480.020
cell migrationGO:00164772380.020
positive regulation of cellular protein metabolic processGO:00322701180.020
negative regulation of transcription dna templatedGO:00458922370.020
appendage developmentGO:00487364010.020
Fly
actin filament polymerizationGO:0030041270.020
anatomical structure homeostasisGO:0060249970.020
regulation of protein polymerizationGO:0032271280.020
growthGO:00400073590.020
appendage morphogenesisGO:00351073970.020
Fly
positive regulation of protein complex assemblyGO:0031334220.020
mesoderm developmentGO:0007498780.020
apoptotic processGO:00069151590.020
negative regulation of nitrogen compound metabolic processGO:00511722650.019
response to biotic stimulusGO:00096072940.019
dendrite developmentGO:00163582040.019
tissue morphogenesisGO:00487292970.019
negative regulation of cell deathGO:0060548810.019
anion homeostasisGO:005508130.019
histolysisGO:00075591020.019
regulation of anatomical structure morphogenesisGO:00226032420.019
regulation of cell morphogenesisGO:00226041630.019
positive regulation of cellular amine metabolic processGO:003324000.019
peptidyl tyrosine phosphorylationGO:0018108240.019
regulation of reproductive processGO:2000241540.019
regulation of protein complex disassemblyGO:0043244290.018
nucleobase containing small molecule metabolic processGO:00550861740.018
myotube cell developmentGO:001490430.018
synapse assemblyGO:00074161430.018
positive regulation of nucleoside metabolic processGO:0045979470.018
actomyosin structure organizationGO:0031032560.018
regulation of cell cycleGO:00517262910.018
regulation of cellular protein metabolic processGO:00322682430.018
chemotaxisGO:00069352490.018
cell projection assemblyGO:0030031940.018
protein maturationGO:0051604710.018
tissue deathGO:00162711020.018
regulation of catabolic processGO:00098941700.018
regulation of growthGO:00400082330.018
endosomal transportGO:0016197440.018
midgut developmentGO:0007494230.018
cellular protein localizationGO:00346131600.017
imaginal disc derived appendage morphogenesisGO:00351143950.017
Fly
single organism biosynthetic processGO:00447112060.017
positive regulation of organelle organizationGO:0010638650.017
positive regulation of phosphorylationGO:0042327870.017
morphogenesis of an epitheliumGO:00020092760.017
negative regulation of protein metabolic processGO:0051248850.017
establishment or maintenance of cytoskeleton polarityGO:0030952440.017
atp catabolic processGO:0006200380.017
specification of organ identityGO:001009230.017
regulation of actin filament polymerizationGO:0030833250.017
regulation of nucleotide metabolic processGO:0006140620.017
carboxylic acid metabolic processGO:0019752920.017
regulation of localizationGO:00328792750.017
regulation of cell differentiationGO:00455953020.017
central nervous system developmentGO:00074172010.017
antimicrobial humoral responseGO:0019730990.017
columnar cuboidal epithelial cell developmentGO:00020662490.016
oxoacid metabolic processGO:00434361030.016
multicellular organismal agingGO:00102591400.016
positive regulation of catalytic activityGO:00430851180.016
nuclear transportGO:0051169720.016
centrosome duplicationGO:00512981210.016
nitrogen compound transportGO:0071705850.016
response to nutrient levelsGO:00316671140.016
kidney epithelium developmentGO:007207330.016
regulation of epidermal growth factor receptor signaling pathwayGO:0042058420.015
negative regulation of sequence specific dna binding transcription factor activityGO:004343340.015
regulation of protein complex assemblyGO:0043254420.015
positive regulation of nucleotide metabolic processGO:0045981550.015
spindle elongationGO:0051231830.015
positive regulation of mitochondrion organizationGO:001082280.015
cellular response to nutrient levelsGO:0031669620.015
dephosphorylationGO:0016311510.015
regulation of gtpase activityGO:0043087440.015
microtubule polymerization or depolymerizationGO:0031109390.015
mitochondrion organizationGO:0007005650.015
cellular amino acid metabolic processGO:0006520610.015
response to abiotic stimulusGO:00096283410.015
phosphatidylinositol mediated signalingGO:004801540.015
mesenchymal cell developmentGO:001403110.015
microtubule depolymerizationGO:0007019250.015
purine ribonucleoside monophosphate catabolic processGO:0009169380.015
regulation of cell cycle phase transitionGO:19019871300.015
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.015
response to radiationGO:00093141550.014
immune system developmentGO:0002520570.014
negative regulation of programmed cell deathGO:0043069720.014
negative regulation of cellular catabolic processGO:0031330340.014
regulation of phosphorylationGO:00423251470.014
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.014
negative regulation of cellular response to oxidative stressGO:190040810.014
establishment of organelle localizationGO:00516561220.014
protein processingGO:0016485680.014
positive regulation of epithelial cell differentiationGO:003085810.014
cellular homeostasisGO:0019725800.014
amine metabolic processGO:0009308120.014
protein secretionGO:0009306450.014
regulation of phosphatidylinositol 3 kinase signalingGO:001406640.014
muscle attachmentGO:0016203360.014
response to starvationGO:0042594970.014
microtubule organizing center organizationGO:00310231680.014
regulation of response to stressGO:00801342000.014
erk1 and erk2 cascadeGO:0070371390.014
gland morphogenesisGO:00226121450.014
response to heatGO:0009408630.014
circulatory system developmentGO:0072359820.014
endomembrane system organizationGO:00102561190.013
extracellular structure organizationGO:0043062460.013
carbohydrate derivative biosynthetic processGO:1901137850.013
rna processingGO:00063961470.013
catechol containing compound biosynthetic processGO:000971330.013
immune responseGO:00069552460.013
segmentationGO:00352822070.013
regulation of cytokinesisGO:003246530.013
taxisGO:00423303040.013
axis specificationGO:00097981670.013
epidermal growth factor receptor signaling pathwayGO:0007173580.013
gtp metabolic processGO:0046039720.013
cell cycle phase transitionGO:00447701400.013
cellular response to starvationGO:0009267610.013
negative regulation of intracellular signal transductionGO:1902532570.013
cellular protein catabolic processGO:0044257830.013
anterior posterior pattern specificationGO:00099521360.012
gland developmentGO:00487321910.012
regulation of endocytosisGO:0030100370.012
camera type eye developmentGO:004301040.012
outflow tract morphogenesisGO:000315140.012
positive regulation of protein metabolic processGO:00512471280.012
regulation of cellular component sizeGO:0032535980.012
regulation of protein depolymerizationGO:1901879270.012
regulation of synaptic transmissionGO:0050804690.012
regulation of extracellular matrix organizationGO:190305340.012
positive regulation of cytoskeleton organizationGO:0051495210.012
regulation of cellular ketone metabolic processGO:001056530.012
kidney developmentGO:000182230.012
synaptic transmission dopaminergicGO:000196320.011
ovarian follicle cell developmentGO:00307072480.011
mitotic sister chromatid segregationGO:0000070870.011
negative regulation of notch signaling pathwayGO:0045746410.011
lipid storageGO:0019915380.011
catecholamine biosynthetic processGO:004242330.011
positive regulation of protein modification processGO:0031401580.011
protein modification by small protein removalGO:0070646280.011
development of primary sexual characteristicsGO:0045137500.011
microtubule polymerizationGO:0046785150.011
regulation of programmed cell deathGO:00430671520.011
negative regulation of multicellular organismal processGO:00512411420.011
epithelial cell migrationGO:00106311480.011
negative regulation of cellular component organizationGO:00511291080.011
neuron recognitionGO:00080381010.011
positive regulation of transportGO:0051050920.011
cardiovascular system developmentGO:0072358820.011
muscle tissue developmentGO:0060537300.011
regulation of oocyte developmentGO:0060281270.011
single organism membrane buddingGO:190259120.011
chromatin silencingGO:0006342760.011
camera type eye morphogenesisGO:004859320.011
negative regulation of cell cycle phase transitionGO:19019881030.011
phosphatidylinositol 3 kinase signalingGO:001406540.011
regulation of myoblast fusionGO:190173960.011
embryonic axis specificationGO:00005781070.011
macromolecule catabolic processGO:00090571610.011
golgi organizationGO:0007030660.011
striated muscle tissue developmentGO:0014706270.011
mitotic cytokinesisGO:0000281500.010
reactive oxygen species metabolic processGO:0072593220.010
gtp catabolic processGO:0006184720.010
protein catabolic processGO:00301631010.010
synaptic vesicle endocytosisGO:0048488280.010
positive regulation of actin filament polymerizationGO:0030838110.010
regulation of apoptotic processGO:00429811300.010
posttranscriptional regulation of gene expressionGO:00106081450.010
vacuolar transportGO:0007034130.010
negative regulation of response to oxidative stressGO:190288310.010
neuron deathGO:0070997270.010
serotonin metabolic processGO:004242820.010
protein localization to organelleGO:0033365820.010
response to oxygen containing compoundGO:19017002000.010

mib2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
organ system cancerDOID:005068600.070
disease of cellular proliferationDOID:1456600.070
cancerDOID:16200.070
disease of anatomical entityDOID:700.038
nervous system diseaseDOID:86300.019
neurodegenerative diseaseDOID:128900.019
central nervous system diseaseDOID:33100.019
synucleinopathyDOID:005089000.019
parkinson s diseaseDOID:1433000.018