Drosophila melanogaster

142 known processes

Trf2 (Dmel_CG18009)

TATA box binding protein-related factor 2

(Aliases: l(1)G0295,trf2,l(1)G0425,l(1)G0071,l(1)G0039,CG11195,CG18009,dTRF2,Dmel\CG18009,TRF2,TLF,p79/TRF2,dTrf2)

Trf2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of rna biosynthetic processGO:19026792400.980
negative regulation of rna metabolic processGO:00512532510.917
negative regulation of cellular biosynthetic processGO:00313272770.856
eye morphogenesisGO:00485922600.765
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.764
negative regulation of biosynthetic processGO:00098902770.752
positive regulation of rna metabolic processGO:00512542710.725
negative regulation of nitrogen compound metabolic processGO:00511722650.721
programmed cell deathGO:00125012570.698
negative regulation of transcription dna templatedGO:00458922370.698
mitotic cell cycle phase transitionGO:00447721380.681
negative regulation of macromolecule biosynthetic processGO:00105582700.637
eye developmentGO:00016543230.632
regulation of cell deathGO:00109411730.596
negative regulation of nucleic acid templated transcriptionGO:19035072400.582
compound eye morphogenesisGO:00017452490.579
transcription from rna polymerase ii promoterGO:00063663680.570
morphogenesis of an epitheliumGO:00020092760.565
positive regulation of gene expressionGO:00106282900.562
negative regulation of cellular metabolic processGO:00313243820.486
negative regulation of gene expressionGO:00106293870.456
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.450
regulation of transcription from rna polymerase ii promoterGO:00063573780.422
photoreceptor cell differentiationGO:00465301700.409
compound eye developmentGO:00487493070.407
regulation of mitotic cell cycle phase transitionGO:19019901300.401
positive regulation of biosynthetic processGO:00098913160.360
negative regulation of nucleobase containing compound metabolic processGO:00459342610.355
eye photoreceptor cell differentiationGO:00017541450.352
cell deathGO:00082192790.315
muscle structure developmentGO:00610612240.313
positive regulation of nitrogen compound metabolic processGO:00511733540.312
dendrite morphogenesisGO:00488131990.307
positive regulation of programmed cell deathGO:0043068620.292
histolysisGO:00075591020.289
positive regulation of transcription dna templatedGO:00458932660.277
sensory organ morphogenesisGO:00905962600.274
gland developmentGO:00487321910.264
regulation of cell differentiationGO:00455953020.263
regulation of growthGO:00400082330.260
regulation of cell cycle phase transitionGO:19019871300.258
negative regulation of mitotic cell cycleGO:00459301090.254
positive regulation of macromolecule metabolic processGO:00106044050.252
developmental programmed cell deathGO:00106231380.249
gene silencingGO:00164581380.247
regulation of cell cycle processGO:00105641810.229
cellular macromolecule catabolic processGO:00442651360.226
embryonic morphogenesisGO:00485982060.226
cellular response to extracellular stimulusGO:0031668640.223
cell cycle phase transitionGO:00447701400.223
regulation of programmed cell deathGO:00430671520.223
mitotic dna integrity checkpointGO:0044774750.212
cell proliferationGO:00082832990.208
dna integrity checkpointGO:0031570810.206
regulation of apoptotic processGO:00429811300.204
lipid metabolic processGO:00066291210.191
circadian behaviorGO:0048512760.188
regulation of mitotic cell cycleGO:00073461900.165
negative regulation of cell cycle processGO:00109481090.160
response to ecdysoneGO:0035075340.158
deathGO:00162652840.155
central nervous system developmentGO:00074172010.152
dna metabolic processGO:00062592270.147
regulation of cell proliferationGO:00421271630.144
negative regulation of cell cycleGO:00457861160.141
induction of programmed cell deathGO:0012502120.139
mitotic g2 m transition checkpointGO:0044818700.139
positive regulation of macromolecule biosynthetic processGO:00105572830.134
cell cycle checkpointGO:0000075950.134
single organism biosynthetic processGO:00447112060.132
response to sterolGO:0036314340.125
positive regulation of cell deathGO:0010942690.117
negative regulation of g1 s transition of mitotic cell cycleGO:2000134130.114
dna damage checkpointGO:0000077780.112
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630110.108
cellular catabolic processGO:00442483720.106
dendrite developmentGO:00163582040.105
positive regulation of cellular biosynthetic processGO:00313283160.098
regulation of protein metabolic processGO:00512462560.097
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.096
mushroom body developmentGO:0016319700.094
exocrine system developmentGO:00352721620.094
photoreceptor cell developmentGO:0042461960.093
regulation of neuron differentiationGO:00456641030.092
compound eye photoreceptor cell differentiationGO:00017511400.091
response to oxygen containing compoundGO:19017002000.088
establishment of localization in cellGO:00516494020.088
tissue morphogenesisGO:00487292970.087
regulation of anatomical structure morphogenesisGO:00226032420.086
apoptotic processGO:00069151590.086
mitotic cell cycle checkpointGO:0007093880.085
lipid biosynthetic processGO:0008610460.085
forebrain developmentGO:003090020.084
establishment of planar polarityGO:0001736870.079
regulation of epithelial cell proliferationGO:005067840.077
positive regulation of rna biosynthetic processGO:19026802660.076
regulation of cell cycleGO:00517262910.076
dna replicationGO:0006260480.072
gland morphogenesisGO:00226121450.072
positive regulation of multicellular organismal processGO:00512401430.071
salivary gland cell autophagic cell deathGO:0035071830.069
positive regulation of developmental processGO:00510941430.068
pupal developmentGO:0035209110.068
negative regulation of gene expression epigeneticGO:0045814770.066
negative regulation of programmed cell deathGO:0043069720.065
regulation of multicellular organismal developmentGO:20000264140.064
cellular response to external stimulusGO:0071496660.064
endocytosisGO:00068973100.063
regulation of cell cycle g1 s phase transitionGO:1902806230.061
regulation of gene silencingGO:0060968630.060
cellular response to nutrient levelsGO:0031669620.059
multicellular organism growthGO:0035264460.059
apoptotic signaling pathwayGO:0097190270.059
rna processingGO:00063961470.058
phagocytosisGO:00069092150.058
negative regulation of cell deathGO:0060548810.057
induction of programmed cell death by ecdysoneGO:0035078120.057
brain developmentGO:00074201200.056
wnt signaling pathwayGO:0016055980.056
segmentationGO:00352822070.056
intracellular signal transductionGO:00355563000.055
meiotic cell cycle processGO:19030461320.054
establishment or maintenance of cell polarityGO:00071631670.053
induction of programmed cell death by hormonesGO:0035081120.052
immune system developmentGO:0002520570.052
microtubule organizing center organizationGO:00310231680.051
embryonic development via the syncytial blastodermGO:00017001480.050
negative regulation of cell cycle g1 s phase transitionGO:1902807130.050
molting cycleGO:0042303560.049
digestive tract developmentGO:00485651490.049
establishment of tissue polarityGO:0007164870.048
er nucleus signaling pathwayGO:000698490.048
regulation of neurogenesisGO:00507671580.048
regionalizationGO:00030024160.048
heterocycle catabolic processGO:00467001660.047
stem cell maintenanceGO:0019827670.043
skeletal muscle organ developmentGO:0060538480.043
modification dependent macromolecule catabolic processGO:0043632790.041
cell cycle dna replicationGO:0044786230.041
eye photoreceptor cell developmentGO:0042462810.041
morphogenesis of follicular epitheliumGO:0016333360.041
ecdysone mediated induction of salivary gland cell autophagic cell deathGO:0035072120.040
organic acid metabolic processGO:00060821030.039
positive regulation of nucleic acid templated transcriptionGO:19035082660.039
instar larval developmentGO:0002168550.039
cellular response to chemical stimulusGO:00708871990.038
macromolecule catabolic processGO:00090571610.038
response to organic substanceGO:00100332840.038
morphogenesis of a polarized epitheliumGO:0001738930.038
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.038
tissue deathGO:00162711020.037
regulation of cellular protein metabolic processGO:00322682430.037
proteolysisGO:00065081920.037
positive regulation of cellular protein metabolic processGO:00322701180.036
salivary gland developmentGO:00074311620.035
response to oxygen levelsGO:0070482590.035
camera type eye morphogenesisGO:004859320.035
single organism behaviorGO:00447083910.034
immune system processGO:00023763470.034
autophagic cell deathGO:0048102830.034
organic substance catabolic processGO:19015753080.034
appendage developmentGO:00487364010.034
cellular protein modification processGO:00064644380.034
regulation of stem cell proliferationGO:0072091400.034
regulation of intracellular signal transductionGO:19025312360.034
regulation of wnt signaling pathwayGO:0030111680.033
multi multicellular organism processGO:00447061230.033
regulation of nervous system developmentGO:00519602480.032
cellular nitrogen compound catabolic processGO:00442701650.032
positive regulation of stem cell proliferationGO:200064880.032
telencephalon developmentGO:002153720.032
aromatic compound catabolic processGO:00194391660.032
nucleus organizationGO:0006997450.031
steroid biosynthetic processGO:0006694160.031
imaginal disc pattern formationGO:0007447910.031
protein localizationGO:00081042840.031
negative regulation of apoptotic processGO:0043066630.031
cellular respirationGO:0045333260.031
small gtpase mediated signal transductionGO:0007264880.031
positive regulation of cell proliferationGO:0008284470.030
generation of precursor metabolites and energyGO:0006091420.030
positive regulation of signalingGO:00230562430.030
vesicle mediated transportGO:00161923810.029
catabolic processGO:00090564090.029
cellular response to organic substanceGO:00713101320.028
cell cell signaling involved in cell fate commitmentGO:00451682100.028
mitotic g2 dna damage checkpointGO:0007095690.028
positive regulation of cell differentiationGO:0045597640.028
dna endoreduplicationGO:0042023220.028
salivary gland histolysisGO:0035070880.027
hindbrain developmentGO:003090220.027
regulation of reproductive processGO:2000241540.027
meiotic cell cycleGO:00513211710.027
multi organism behaviorGO:00517051750.027
response to hexoseGO:000974630.027
regulation of organelle organizationGO:00330431960.026
growthGO:00400073590.026
regulation of chromatin silencingGO:0031935360.025
negative regulation of developmental processGO:00510932010.025
single organism intracellular transportGO:19025822070.025
negative regulation of mitotic cell cycle phase transitionGO:19019911030.025
intracellular transportGO:00469072280.025
response to abiotic stimulusGO:00096283410.024
salivary gland morphogenesisGO:00074351450.024
regulation of steroid metabolic processGO:001921820.024
homeostatic processGO:00425921990.024
response to lipidGO:0033993380.024
regulation of neuroblast proliferationGO:1902692340.024
negative regulation of epithelial cell proliferationGO:005068040.024
response to nutrient levelsGO:00316671140.023
ketone biosynthetic processGO:0042181160.023
cellular response to oxygen containing compoundGO:1901701790.023
vitamin metabolic processGO:000676620.022
organelle fissionGO:00482853400.022
developmental growthGO:00485892800.021
segment specificationGO:0007379330.021
stem cell proliferationGO:0072089880.021
leg disc morphogenesisGO:0007478800.021
negative regulation of cell cycle phase transitionGO:19019881030.021
positive regulation of cell communicationGO:00106472500.020
cellular response to abiotic stimulusGO:0071214580.020
nucleocytoplasmic transportGO:0006913720.020
gene silencing by rnaGO:0031047570.020
response to temperature stimulusGO:00092661060.020
neuron maturationGO:0042551310.020
positive regulation of wnt signaling pathwayGO:0030177250.020
regulation of developmental growthGO:00486381740.020
positive regulation of cell developmentGO:0010720610.019
negative regulation of growthGO:0045926840.019
ncrna metabolic processGO:0034660430.019
phosphorylationGO:00163102940.019
axon developmentGO:00615642970.019
sterol homeostasisGO:005509240.019
positive regulation of signal transductionGO:00099672230.018
negative regulation of signalingGO:00230572190.018
positive regulation of protein metabolic processGO:00512471280.018
centrosome cycleGO:00070981370.018
fusion cell fate specificationGO:003515640.018
rhythmic processGO:00485111060.018
carbohydrate metabolic processGO:0005975820.018
regulation of cell shapeGO:00083601130.018
positive regulation of nucleobase containing compound metabolic processGO:00459353320.018
compound eye photoreceptor developmentGO:0042051780.018
organic cyclic compound catabolic processGO:19013611680.018
regulation of photoreceptor cell differentiationGO:0046532340.018
protein acetylationGO:0006473390.018
histone h3 acetylationGO:0043966110.018
glial cell fate commitmentGO:002178130.017
cellular response to hormone stimulusGO:0032870440.017
acylglycerol biosynthetic processGO:004646320.017
chromatin modificationGO:00165681470.017
chromatin organizationGO:00063252070.017
oxoacid metabolic processGO:00434361030.017
regulation of protein localizationGO:0032880760.017
response to starvationGO:0042594970.017
chemical homeostasisGO:0048878920.017
divalent inorganic cation homeostasisGO:0072507290.016
head developmentGO:00603221350.016
pupariationGO:0035073140.016
nuclear divisionGO:00002803320.016
cellular response to decreased oxygen levelsGO:0036294300.016
gonad developmentGO:0008406500.016
regulation of multicellular organism growthGO:0040014400.016
protein modification by small protein conjugation or removalGO:00706471060.016
neuron projection guidanceGO:00974852410.016
cellular response to dna damage stimulusGO:00069742230.016
positive regulation of catalytic activityGO:00430851180.016
regulation of epithelial cell differentiationGO:003085640.016
negative regulation of neuroblast proliferationGO:0007406270.016
g2 dna damage checkpointGO:0031572690.015
regulation of g1 s transition of mitotic cell cycleGO:2000045230.015
positive regulation of response to stimulusGO:00485843230.015
cellular response to oxygen levelsGO:0071453300.015
energy derivation by oxidation of organic compoundsGO:0015980320.015
monocarboxylic acid metabolic processGO:0032787290.014
protein localization to nucleusGO:0034504550.014
stem cell differentiationGO:00488631170.014
neuron remodelingGO:0016322290.014
nucleobase containing compound catabolic processGO:00346551650.014
negative regulation of cell differentiationGO:00455961430.014
positive regulation of neuron apoptotic processGO:004352510.014
cellular response to starvationGO:0009267610.014
retina development in camera type eyeGO:006004140.014
molting cycle processGO:0022404290.014
histone h4 acetylationGO:0043967130.013
embryo development ending in birth or egg hatchingGO:00097921520.013
organophosphate metabolic processGO:00196371950.013
positive regulation of growthGO:0045927750.013
protein localization to organelleGO:0033365820.013
regulation of chromatin modificationGO:1903308280.013
rna polyadenylationGO:0043631120.013
centrosome organizationGO:00512971630.013
ecdysis chitin based cuticleGO:001899080.013
response to alcoholGO:0097305950.013
maintenance of locationGO:0051235730.013
respiratory system developmentGO:00605412130.013
neuroblast differentiationGO:0014016290.013
regulation of cell developmentGO:00602842150.013
response to toxic substanceGO:0009636220.012
leg disc developmentGO:0035218920.012
positive regulation of bindingGO:005109940.012
nuclear transportGO:0051169720.012
metal ion homeostasisGO:0055065440.012
regulation of protein deacetylationGO:009031120.012
chromatin silencingGO:0006342760.012
protein modification processGO:00362114380.012
molting cycle chitin based cuticleGO:0007591560.012
oxidation reduction processGO:00551141230.012
response to extracellular stimulusGO:00099911160.012
cellular macromolecular complex assemblyGO:00346221530.012
posttranscriptional regulation of gene expressionGO:00106081450.012
mesenchymal cell developmentGO:001403110.012
cellular carbohydrate metabolic processGO:0044262220.012
response to endogenous stimulusGO:00097191190.012
periodic partitioningGO:0007365290.012
wing disc pattern formationGO:0035222660.011
positive regulation of neurogenesisGO:0050769410.011
positive regulation of r7 cell differentiationGO:004567870.011
positive regulation of stem cell differentiationGO:200073830.011
carboxylic acid metabolic processGO:0019752920.011
muscle tissue developmentGO:0060537300.011
cellular response to lipidGO:0071396200.011
rhythmic behaviorGO:0007622760.011
chromatin remodelingGO:0006338720.011
rna catabolic processGO:0006401370.011
negative regulation of wnt signaling pathwayGO:0030178280.011
spindle organizationGO:00070512530.010
regulation of chromosome segregationGO:0051983320.010
ribonucleoprotein complex biogenesisGO:0022613310.010
dorsal closureGO:0007391790.010
appendage morphogenesisGO:00351073970.010
neuroblast proliferationGO:0007405740.010
axonogenesisGO:00074092900.010
cuticle pigmentationGO:0048067220.010
limb developmentGO:006017310.010
protein import into nucleusGO:0006606510.010
camera type eye developmentGO:004301040.010
proteasomal protein catabolic processGO:0010498590.010
positive regulation of mitotic cell cycleGO:0045931340.010
response to lipopolysaccharideGO:003249640.010
rrna processingGO:000636430.010
ecdysone receptor mediated signaling pathwayGO:0035076110.010
circadian rhythmGO:00076231050.010

Trf2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
carbohydrate metabolism diseaseDOID:005001300.094
disease of metabolismDOID:001466700.094
glucose metabolism diseaseDOID:419400.094
acquired metabolic diseaseDOID:006015800.094
disease of cellular proliferationDOID:1456600.019
cancerDOID:16200.019