Drosophila melanogaster

5 known processes

Cyp12a4 (Dmel_CG6042)

CG6042 gene product from transcript CG6042-RA

(Aliases: Dmel\CG6042,cyp12a4,12a4,P450,CG6042,CYP12A4)

Cyp12a4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
insecticide metabolic processGO:001714321.000
secondary metabolite catabolic processGO:009048710.998
medium chain fatty acid metabolic processGO:005179110.995
response to mercury ionGO:004668930.993
toxin catabolic processGO:000940710.990
insecticide catabolic processGO:004670110.984
lauric acid metabolic processGO:004825210.980
response to toxic substanceGO:0009636220.974
organic hydroxy compound biosynthetic processGO:1901617210.944
Fly
response to ddtGO:004668050.913
Fly
steroid catabolic processGO:000670610.895
ketone biosynthetic processGO:0042181160.879
Fly
polyol biosynthetic processGO:004617330.874
fat soluble vitamin biosynthetic processGO:004236210.857
vitamin biosynthetic processGO:000911010.843
regulation of tube sizeGO:0035150460.824
sterol metabolic processGO:0016125120.810
Fly
xenobiotic catabolic processGO:004217810.789
cellular hormone metabolic processGO:0034754230.755
Fly
vitamin metabolic processGO:000676620.736
steroid biosynthetic processGO:0006694160.732
Fly
response to insecticideGO:0017085140.717
organic hydroxy compound metabolic processGO:1901615830.700
Fly
alcohol biosynthetic processGO:0046165140.679
Fly
anion homeostasisGO:005508130.678
multi organism behaviorGO:00517051750.648
aggressive behaviorGO:0002118630.634
ecdysone biosynthetic processGO:000669790.601
Fly
sensory perception of smellGO:0007608800.591
tissue migrationGO:00901301550.590
Fly
sterol biosynthetic processGO:001612690.577
Fly
response to caffeineGO:0031000120.572
fatty acid metabolic processGO:0006631200.565
hormone biosynthetic processGO:0042446200.552
Fly
fat soluble vitamin metabolic processGO:000677510.510
sensory perception of chemical stimulusGO:00076061160.499
ecdysteroid biosynthetic processGO:0045456150.464
Fly
response to organophosphorusGO:004668320.462
response to organic substanceGO:00100332840.457
Fly
positive regulation of multicellular organismal processGO:00512401430.437
alcohol metabolic processGO:0006066250.431
Fly
lipid catabolic processGO:0016042210.419
regulation of anatomical structure sizeGO:00900661630.416
response to xenobiotic stimulusGO:000941050.404
ecdysone metabolic processGO:0008205110.404
Fly
single organism biosynthetic processGO:00447112060.388
Fly
sensory perceptionGO:00076001960.386
organonitrogen compound catabolic processGO:19015651280.357
small molecule metabolic processGO:00442813050.353
Fly
developmental growthGO:00485892800.344
Fly
response to nitrogen compoundGO:1901698900.341
secondary metabolic processGO:0019748750.332
epithelium migrationGO:00901321480.321
Fly
ovarian follicle cell migrationGO:00072971210.318
Fly
growthGO:00400073590.304
Fly
cellular ketone metabolic processGO:0042180240.303
Fly
steroid metabolic processGO:0008202200.300
Fly
lipid biosynthetic processGO:0008610460.296
Fly
toxin metabolic processGO:000940420.293
regulation of developmental growthGO:00486381740.289
ecdysteroid metabolic processGO:0045455190.287
Fly
cellular ion homeostasisGO:0006873390.283
response to purine containing compoundGO:0014074120.261
terpenoid metabolic processGO:000672170.258
positive regulation of gene expressionGO:00106282900.254
cellular catabolic processGO:00442483720.252
epithelial cell developmentGO:00020642740.252
Fly
chemical homeostasisGO:0048878920.251
response to temperature stimulusGO:00092661060.247
lipid metabolic processGO:00066291210.244
Fly
neurological system processGO:00508773580.238
response to organic cyclic compoundGO:0014070890.227
Fly
cellular lipid metabolic processGO:0044255830.226
oxidation reduction processGO:00551141230.226
Fly
isoprenoid metabolic processGO:000672080.225
response to external biotic stimulusGO:00432072930.218
small molecule biosynthetic processGO:0044283370.215
Fly
hormone metabolic processGO:0042445330.215
Fly
positive regulation of macromolecule metabolic processGO:00106044050.214
dorsal closureGO:0007391790.211
Fly
monocarboxylic acid metabolic processGO:0032787290.209
catabolic processGO:00090564090.207
organonitrogen compound metabolic processGO:19015643180.206
carboxylic acid metabolic processGO:0019752920.203
response to metal ionGO:0010038230.199
response to alkaloidGO:0043279260.199
regulation of system processGO:0044057360.198
homeostatic processGO:00425921990.183
single organism catabolic processGO:00447122280.181
organic cyclic compound catabolic processGO:19013611680.175
ameboidal type cell migrationGO:00016671510.167
Fly
organic acid metabolic processGO:00060821030.165
response to abiotic stimulusGO:00096283410.163
organic substance catabolic processGO:19015753080.160
cellular nitrogen compound catabolic processGO:00442701650.160
ion homeostasisGO:0050801550.154
columnar cuboidal epithelial cell differentiationGO:00020652560.152
Fly
response to lipidGO:0033993380.151
embryonic development via the syncytial blastodermGO:00017001480.145
Fly
defense response to bacteriumGO:00427421780.141
response to other organismGO:00517072930.137
single organism behaviorGO:00447083910.135
border follicle cell migrationGO:00072981130.132
Fly
response to endogenous stimulusGO:00097191190.129
cellular chemical homeostasisGO:0055082400.127
response to biotic stimulusGO:00096072940.127
cellular homeostasisGO:0019725800.126
response to extracellular stimulusGO:00099911160.125
regulation of growthGO:00400082330.120
response to nutrient levelsGO:00316671140.114
regulation of blood circulationGO:1903522210.113
response to inorganic substanceGO:0010035440.109
defense response to other organismGO:00985422250.107
response to organonitrogen compoundGO:0010243750.106
chitin based embryonic cuticle biosynthetic processGO:0008362160.098
Fly
response to bacteriumGO:00096171980.097
gland developmentGO:00487321910.097
tergite morphogenesisGO:000749010.096
Fly
tissue morphogenesisGO:00487292970.093
Fly
cell motilityGO:00488702510.092
Fly
defense responseGO:00069523000.081
cellular response to chemical stimulusGO:00708871990.078
ovarian follicle cell developmentGO:00307072480.078
Fly
response to oxygen containing compoundGO:19017002000.075
appendage developmentGO:00487364010.075
agingGO:00075681430.074
epithelial cell migrationGO:00106311480.073
Fly
cell migrationGO:00164772380.071
Fly
imaginal disc derived appendage developmentGO:00487373990.070
localization of cellGO:00516742570.070
Fly
regulation of hormone levelsGO:0010817400.069
Fly
acetate ester metabolic processGO:190061920.068
morphogenesis of an epitheliumGO:00020092760.064
Fly
defense response to gram negative bacteriumGO:0050829940.064
response to hormoneGO:0009725450.063
oxoacid metabolic processGO:00434361030.063
circulatory system processGO:0003013370.062
hormone catabolic processGO:004244730.062
epithelial cell differentiationGO:00308553220.062
Fly
imaginal disc derived appendage morphogenesisGO:00351143950.062
wing disc morphogenesisGO:00074723440.062
response to transition metal nanoparticleGO:199026790.060
synaptic transmissionGO:00072682880.060
digestive tract developmentGO:00485651490.057
Fly
androgen metabolic processGO:000820910.056
central nervous system developmentGO:00074172010.055
Fly
morphogenesis of embryonic epitheliumGO:0016331940.054
Fly
positive regulation of response to stimulusGO:00485843230.052
embryonic morphogenesisGO:00485982060.050
Fly
response to lipopolysaccharideGO:003249640.050
chitin based cuticle developmentGO:0040003490.047
Fly
detection of stimulusGO:00516061560.047
xenobiotic metabolic processGO:000680550.046
heterocycle catabolic processGO:00467001660.045
response to alcoholGO:0097305950.045
aromatic compound catabolic processGO:00194391660.045
blood circulationGO:0008015260.044
meiotic cell cycle processGO:19030461320.044
cuticle developmentGO:0042335860.044
Fly
mitotic spindle organizationGO:00070522200.042
columnar cuboidal epithelial cell developmentGO:00020662490.041
Fly
embryo development ending in birth or egg hatchingGO:00097921520.041
Fly
regulation of multicellular organismal developmentGO:20000264140.040
head involutionGO:0008258350.040
Fly
post embryonic appendage morphogenesisGO:00351203850.039
acetylcholine metabolic processGO:000829120.038
cell proliferationGO:00082832990.038
positive regulation of cell migrationGO:003033520.037
midgut developmentGO:0007494230.037
Fly
spindle organizationGO:00070512530.037
protein modification processGO:00362114380.036
protein complex biogenesisGO:00702712010.035
regulation of localizationGO:00328792750.035
imaginal disc derived wing morphogenesisGO:00074763370.035
cellular response to xenobiotic stimulusGO:007146650.035
chaeta developmentGO:0022416970.035
digestive system developmentGO:00551231490.035
Fly
protein complex assemblyGO:00064612000.035
cellular amine metabolic processGO:0044106120.035
response to copper ionGO:004668840.034
telencephalon developmentGO:002153720.033
cellular amino acid metabolic processGO:0006520610.033
estrogen metabolic processGO:000821010.032
multicellular organismal reproductive behaviorGO:00330571100.032
forebrain developmentGO:003090020.032
regulation of cellular ketone metabolic processGO:001056530.031
multi organism reproductive behaviorGO:00447051210.031
appendage morphogenesisGO:00351073970.030
vesicle mediated transportGO:00161923810.030
macromolecular complex assemblyGO:00650032560.030
cell deathGO:00082192790.030
programmed cell deathGO:00125012570.029
phototransductionGO:0007602520.029
response to drugGO:0042493170.029
kidney developmentGO:000182230.029
positive regulation of cell motilityGO:200014730.029
transmembrane transportGO:00550851390.028
neuron recognitionGO:00080381010.028
response to cadmium ionGO:004668690.028
positive regulation of signal transductionGO:00099672230.027
deathGO:00162652840.027
regulation of behaviorGO:0050795750.027
regulation of multi organism processGO:00439001310.026
thermosensory behaviorGO:0040040190.026
cellular protein modification processGO:00064644380.025
multi multicellular organism processGO:00447061230.025
endocytosisGO:00068973100.025
regulation of reproductive processGO:2000241540.024
meiotic nuclear divisionGO:00071261510.024
mitotic spindle elongationGO:0000022810.024
regulation of molecular functionGO:00650092170.024
intracellular signal transductionGO:00355563000.023
negative regulation of cellular biosynthetic processGO:00313272770.023
actin filament organizationGO:00070151260.022
tube developmentGO:00352952440.022
Fly
positive regulation of cell communicationGO:00106472500.022
ethanolamine containing compound metabolic processGO:004243940.022
tissue deathGO:00162711020.021
regulation of transportGO:00510491810.021
camera type eye developmentGO:004301040.021
autophagic cell deathGO:0048102830.020
response to ethanolGO:0045471590.020
water homeostasisGO:003010430.020
chromosome segregationGO:00070591570.020
phosphorylationGO:00163102940.020
determination of adult lifespanGO:00083401370.020
response to monosaccharideGO:003428440.020
acetylcholine catabolic processGO:000658110.019
phagocytosisGO:00069092150.019
benzene containing compound metabolic processGO:004253730.019
gland morphogenesisGO:00226121450.019
amine metabolic processGO:0009308120.019
positive regulation of signalingGO:00230562430.019
exocrine system developmentGO:00352721620.018
salivary gland morphogenesisGO:00074351450.018
inter male aggressive behaviorGO:0002121600.018
single organism intracellular transportGO:19025822070.018
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.018
cellular response to nitrogen compoundGO:1901699510.018
neurotransmitter metabolic processGO:004213320.018
positive regulation of nucleobase containing compound metabolic processGO:00459353320.018
negative regulation of biosynthetic processGO:00098902770.018
cellular response to organic substanceGO:00713101320.018
protein transportGO:00150311550.018
regulation of response to stressGO:00801342000.018
cellular response to ketoneGO:1901655170.018
regulation of ovipositionGO:0046662140.018
nucleoside catabolic processGO:00091641120.017
positive regulation of cellular component biogenesisGO:0044089800.017
reproductive behaviorGO:00190981220.017
salivary gland cell autophagic cell deathGO:0035071830.017
mrna processingGO:00063971040.017
response to glucoseGO:000974920.017
motor neuron axon guidanceGO:0008045580.017
positive regulation of cellular component organizationGO:00511301560.016
regulation of cellular component biogenesisGO:00440872010.016
synapse assemblyGO:00074161430.016
positive regulation of catalytic activityGO:00430851180.016
female meiotic divisionGO:0007143700.016
axon guidanceGO:00074112330.016
small molecule catabolic processGO:0044282210.015
positive regulation of molecular functionGO:00440931360.015
multicellular organismal agingGO:00102591400.015
nucleocytoplasmic transportGO:0006913720.015
positive regulation of intracellular signal transductionGO:19025331160.015
renal system processGO:0003014120.015
organic substance transportGO:00717022570.015
synaptic target recognitionGO:0008039450.015
positive regulation of transportGO:0051050920.015
regulation of intracellular signal transductionGO:19025312360.015
intracellular transportGO:00469072280.015
pyridine containing compound metabolic processGO:007252430.015
negative regulation of cellular metabolic processGO:00313243820.014
cellular protein complex disassemblyGO:0043624350.014
establishment of localization in cellGO:00516494020.014
detection of light stimulusGO:0009583580.014
cellular biogenic amine catabolic processGO:004240210.014
cellular response to ethanolGO:007136140.014
response to oxidative stressGO:0006979860.014
cellular response to hexose stimulusGO:007133110.014
nucleobase containing compound catabolic processGO:00346551650.014
response to light stimulusGO:00094161240.014
maintenance of locationGO:0051235730.014
regulation of programmed cell deathGO:00430671520.013
salivary gland developmentGO:00074311620.013
cellular response to organonitrogen compoundGO:0071417360.013
negative regulation of response to stimulusGO:00485852580.013
enzyme linked receptor protein signaling pathwayGO:00071671790.013
negative regulation of rna metabolic processGO:00512532510.013
brain developmentGO:00074201200.013
organophosphate catabolic processGO:00464341120.013
cell recognitionGO:00080371020.013
single organism carbohydrate metabolic processGO:0044723720.013
axonogenesisGO:00074092900.013
immune response activating signal transductionGO:000275720.013
cell projection assemblyGO:0030031940.013
carbohydrate derivative metabolic processGO:19011352170.013
regulation of i kappab kinase nf kappab signalingGO:004312220.013
negative regulation of nucleobase containing compound metabolic processGO:00459342610.012
positive regulation of phosphate metabolic processGO:00459371390.012
detection of abiotic stimulusGO:0009582660.012
response to radiationGO:00093141550.012
female meiosis chromosome segregationGO:0016321330.012
immune response regulating signaling pathwayGO:000276420.012
choline metabolic processGO:001969510.012
developmental maturationGO:00217001720.012
epidermis developmentGO:0008544650.012
axon developmentGO:00615642970.012
macromolecular complex disassemblyGO:0032984370.012
pattern recognition receptor signaling pathwayGO:000222120.012
neurotransmitter catabolic processGO:004213510.012
synapse organizationGO:00508081960.012
neuron projection guidanceGO:00974852410.012
respiratory system developmentGO:00605412130.012
mrna splicing via spliceosomeGO:0000398730.012
glutamate metabolic processGO:000653650.012
cellular response to peptideGO:1901653280.012
activation of innate immune responseGO:000221840.012
regulation of cell deathGO:00109411730.011
regionalizationGO:00030024160.011
protein localizationGO:00081042840.011
cellular macromolecular complex assemblyGO:00346221530.011
organelle fissionGO:00482853400.011
maintenance of imaginal disc derived wing hair orientationGO:003532130.011
body morphogenesisGO:001017120.011
open tracheal system developmentGO:00074242040.011
head developmentGO:00603221350.011
choline catabolic processGO:004242610.011
regulation of cell differentiationGO:00455953020.011
positive regulation of phosphorus metabolic processGO:00105621390.011
regulation of apoptotic processGO:00429811300.011
rhythmic behaviorGO:0007622760.011
regulation of cellular localizationGO:00603411360.011
cell maturationGO:00484691440.011
negative regulation of nitrogen compound metabolic processGO:00511722650.011
response to hexoseGO:000974630.011
ion transportGO:00068111450.011
imaginal disc derived wing hair organizationGO:0035317450.011
purine ribonucleoside catabolic processGO:00461301120.011
regulation of catalytic activityGO:00507901850.011
cellular response to oxygen containing compoundGO:1901701790.011
regulation of cellular protein metabolic processGO:00322682430.011
cellular component disassemblyGO:0022411460.011
epidermal cell differentiationGO:0009913510.011
small gtpase mediated signal transductionGO:0007264880.011
innate immune response activating signal transductionGO:000275820.011
mrna metabolic processGO:00160711240.011
nuclear divisionGO:00002803320.011
regulation of immune system processGO:00026821760.011
cellular macromolecule localizationGO:00707272200.011
regulation of phosphorus metabolic processGO:00511742100.011
purine ribonucleotide metabolic processGO:00091501450.011
histoblast morphogenesisGO:000748890.011
Fly
regulation of catabolic processGO:00098941700.011
establishment of blood nerve barrierGO:000806520.011
rna splicingGO:0008380830.011
phosphate ion transportGO:000681740.011
nucleotide metabolic processGO:00091171610.011
positive regulation of developmental processGO:00510941430.011
positive regulation of purine nucleotide metabolic processGO:1900544550.010
positive regulation of biosynthetic processGO:00098913160.010
lateral inhibitionGO:00463312060.010
apoptotic processGO:00069151590.010
regulation of cellular response to stressGO:0080135890.010
positive regulation of macromolecule biosynthetic processGO:00105572830.010
circadian rhythmGO:00076231050.010
regulation of cell proliferationGO:00421271630.010
cellular response to endogenous stimulusGO:0071495800.010
histolysisGO:00075591020.010
regulation of phosphate metabolic processGO:00192202100.010
pigment metabolic process involved in pigmentationGO:0043474330.010

Cyp12a4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
artery diseaseDOID:005082800.907
hypertensionDOID:1076300.907
cardiovascular system diseaseDOID:128700.907
disease of anatomical entityDOID:700.907
vascular diseaseDOID:17800.907
essential hypertensionDOID:1082500.907
disease of metabolismDOID:001466700.017
inherited metabolic disorderDOID:65500.013
nervous system diseaseDOID:86300.012
glucose metabolism diseaseDOID:419400.010
acquired metabolic diseaseDOID:006015800.010
carbohydrate metabolism diseaseDOID:005001300.010