Drosophila melanogaster

195 known processes

eve (Dmel_CG2328)

even skipped

(Aliases: l(2)46CFh,10.5,20.35,F,10.9,VI,E(eve),V,EVE,Eve,l(2)46CFj,l(2)46CFp,14.10,CG2328,Dmel\CG2328,l(2)46CFg,eve2,l(2)46Cg,l(2)46Ce)

eve biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
motor neuron axon guidanceGO:0008045580.999
neuron projection guidanceGO:00974852410.994
axonogenesisGO:00074092900.985
negative regulation of transcription dna templatedGO:00458922370.973
taxisGO:00423303040.964
positive regulation of rna metabolic processGO:00512542710.943
axon guidanceGO:00074112330.935
negative regulation of nucleobase containing compound metabolic processGO:00459342610.932
epithelial cell differentiationGO:00308553220.930
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.918
regionalizationGO:00030024160.915
torso signaling pathwayGO:0008293210.909
transcription from rna polymerase ii promoterGO:00063663680.897
response to organic substanceGO:00100332840.886
positive regulation of nucleic acid templated transcriptionGO:19035082660.853
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.829
positive regulation of biosynthetic processGO:00098913160.811
positive regulation of gene expressionGO:00106282900.799
heart developmentGO:0007507820.783
regulation of cell fate commitmentGO:0010453290.779
negative regulation of cellular biosynthetic processGO:00313272770.774
positive regulation of rna biosynthetic processGO:19026802660.774
cardioblast differentiationGO:0010002200.765
cell fate specificationGO:0001708710.744
regulation of muscle organ developmentGO:0048634130.737
renal tubule developmentGO:0061326640.728
positive regulation of macromolecule metabolic processGO:00106044050.725
cardiocyte differentiationGO:0035051290.686
central nervous system developmentGO:00074172010.685
regulation of multicellular organismal developmentGO:20000264140.685
regulation of transcription from rna polymerase ii promoterGO:00063573780.680
tube developmentGO:00352952440.676
negative regulation of nitrogen compound metabolic processGO:00511722650.675
positive regulation of transcription dna templatedGO:00458932660.660
regulation of myotube differentiationGO:001083060.659
circulatory system developmentGO:0072359820.633
heart morphogenesisGO:0003007320.631
tube morphogenesisGO:00352391910.627
muscle structure developmentGO:00610612240.607
enzyme linked receptor protein signaling pathwayGO:00071671790.601
eye morphogenesisGO:00485922600.589
regulation of neurogenesisGO:00507671580.577
digestive system developmentGO:00551231490.575
malpighian tubule developmentGO:0072002640.575
axon developmentGO:00615642970.547
syncytium formationGO:0006949430.539
cellular response to chemical stimulusGO:00708871990.539
negative regulation of biosynthetic processGO:00098902770.538
embryonic heart tube developmentGO:0035050220.525
tissue morphogenesisGO:00487292970.522
segmentationGO:00352822070.520
positive regulation of response to stimulusGO:00485843230.517
renal system developmentGO:0072001720.507
columnar cuboidal epithelial cell developmentGO:00020662490.499
dendrite developmentGO:00163582040.485
mesoderm developmentGO:0007498780.482
cellular response to endogenous stimulusGO:0071495800.480
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.479
negative regulation of gene expressionGO:00106293870.467
positive regulation of macromolecule biosynthetic processGO:00105572830.461
chemotaxisGO:00069352490.454
positive regulation of nucleobase containing compound metabolic processGO:00459353320.447
eye developmentGO:00016543230.446
Fly
imaginal disc derived appendage developmentGO:00487373990.438
regulation of anatomical structure morphogenesisGO:00226032420.419
sensory organ morphogenesisGO:00905962600.411
dendrite morphogenesisGO:00488131990.410
imaginal disc derived appendage morphogenesisGO:00351143950.403
neuron fate commitmentGO:0048663500.390
regulation of cell differentiationGO:00455953020.386
embryonic pattern specificationGO:00098801740.379
myotube differentiationGO:0014902460.375
kidney epithelium developmentGO:007207330.358
salivary gland morphogenesisGO:00074351450.357
negative regulation of rna biosynthetic processGO:19026792400.355
compound eye developmentGO:00487493070.347
Fly
response to oxygen containing compoundGO:19017002000.345
embryonic morphogenesisGO:00485982060.343
stem cell differentiationGO:00488631170.342
gland developmentGO:00487321910.342
negative regulation of nucleic acid templated transcriptionGO:19035072400.341
apoptotic processGO:00069151590.341
regulation of syncytium formation by plasma membrane fusionGO:006014260.340
morphogenesis of embryonic epitheliumGO:0016331940.339
circulatory system processGO:0003013370.333
muscle cell differentiationGO:00426921030.331
cell cell signaling involved in cell fate commitmentGO:00451682100.330
negative regulation of cell fate specificationGO:0009996150.329
zygotic determination of anterior posterior axis embryoGO:0007354270.328
compound eye morphogenesisGO:00017452490.323
appendage developmentGO:00487364010.322
negative regulation of cell differentiationGO:00455961430.319
morphogenesis of an epitheliumGO:00020092760.315
terminal region determinationGO:0007362250.315
response to alcoholGO:0097305950.310
positive regulation of cellular biosynthetic processGO:00313283160.309
compound eye photoreceptor cell differentiationGO:00017511400.308
digestive tract morphogenesisGO:00485461270.302
regulation of cell proliferationGO:00421271630.302
brain developmentGO:00074201200.301
positive regulation of cell proliferationGO:0008284470.296
cell proliferationGO:00082832990.293
growthGO:00400073590.293
embryonic hindgut morphogenesisGO:0048619480.289
immune system processGO:00023763470.288
immune responseGO:00069552460.287
chromatin modificationGO:00165681470.286
positive regulation of cell communicationGO:00106472500.286
regulation of nervous system developmentGO:00519602480.286
columnar cuboidal epithelial cell differentiationGO:00020652560.284
cardiovascular system developmentGO:0072358820.283
stem cell developmentGO:0048864790.282
positive regulation of nitrogen compound metabolic processGO:00511733540.281
salivary gland developmentGO:00074311620.281
positive regulation of cellular component organizationGO:00511301560.279
organic hydroxy compound metabolic processGO:1901615830.277
exocrine system developmentGO:00352721620.275
appendage morphogenesisGO:00351073970.274
embryonic organ developmentGO:0048568500.272
cellular response to organic substanceGO:00713101320.270
neuron recognitionGO:00080381010.267
cell maturationGO:00484691440.264
protein complex biogenesisGO:00702712010.261
striated muscle cell differentiationGO:0051146900.260
digestive tract developmentGO:00485651490.255
regulation of cellular protein metabolic processGO:00322682430.249
negative regulation of cellular metabolic processGO:00313243820.247
cell motilityGO:00488702510.247
head developmentGO:00603221350.242
border follicle cell migrationGO:00072981130.238
cardioblast cell fate commitmentGO:0042684140.238
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.231
muscle cell developmentGO:0055001500.223
ameboidal type cell migrationGO:00016671510.223
cellular protein modification processGO:00064644380.221
response to abiotic stimulusGO:00096283410.220
ovarian follicle cell developmentGO:00307072480.219
epithelial tube morphogenesisGO:0060562880.218
connective tissue developmentGO:006144830.217
post embryonic appendage morphogenesisGO:00351203850.217
negative regulation of nervous system developmentGO:0051961920.216
multicellular organism growthGO:0035264460.216
spinal cord developmentGO:002151010.216
regulation of cellular ketone metabolic processGO:001056530.215
malpighian tubule morphogenesisGO:0007443440.214
myoblast proliferationGO:005145030.211
hindgut morphogenesisGO:0007442580.211
heart processGO:0003015370.209
urogenital system developmentGO:0001655720.204
regulation of developmental growthGO:00486381740.202
regulation of muscle cell differentiationGO:005114780.198
response to endogenous stimulusGO:00097191190.194
oxoacid metabolic processGO:00434361030.193
gonad developmentGO:0008406500.192
blastoderm segmentationGO:00073501590.191
eye photoreceptor cell fate commitmentGO:0042706370.191
somatic stem cell divisionGO:0048103370.189
response to growth factorGO:0070848310.188
response to organic cyclic compoundGO:0014070890.184
positive regulation of developmental processGO:00510941430.183
amine metabolic processGO:0009308120.180
negative regulation of rna metabolic processGO:00512532510.180
regulation of neuron differentiationGO:00456641030.177
regulation of apoptotic processGO:00429811300.176
cellular amine metabolic processGO:0044106120.175
imaginal disc derived wing morphogenesisGO:00074763370.171
protein modification processGO:00362114380.171
development of primary sexual characteristicsGO:0045137500.169
gastrulation with mouth forming firstGO:0001703360.167
periodic partitioningGO:0007365290.166
deathGO:00162652840.161
biological adhesionGO:00226101380.161
lateral inhibitionGO:00463312060.161
anterior posterior pattern specificationGO:00099521360.161
neuron fate specificationGO:0048665120.160
photoreceptor cell differentiationGO:00465301700.152
telencephalon developmentGO:002153720.147
cell adhesionGO:00071551360.143
regulation of immune system processGO:00026821760.143
eye photoreceptor cell differentiationGO:00017541450.141
regulation of molecular functionGO:00650092170.139
nephron morphogenesisGO:007202830.138
mesenchymal cell differentiationGO:004876210.136
negative regulation of macromolecule biosynthetic processGO:00105582700.134
phosphorylationGO:00163102940.133
regulation of protein metabolic processGO:00512462560.132
anterior posterior axis specificationGO:00099481090.130
cellular ketone metabolic processGO:0042180240.126
compound eye photoreceptor fate commitmentGO:0001752360.125
hematopoietic or lymphoid organ developmentGO:0048534570.122
cell migrationGO:00164772380.119
tripartite regional subdivisionGO:00073511030.117
protein complex assemblyGO:00064612000.116
gastrulationGO:0007369700.115
nephron tubule morphogenesisGO:007207830.115
cardiac cell fate commitmentGO:0060911170.114
epithelial cell migrationGO:00106311480.114
body morphogenesisGO:001017120.113
Worm
regulation of protein modification processGO:00313991120.113
tissue migrationGO:00901301550.112
bmp signaling pathwayGO:0030509270.111
dorsal ventral pattern formationGO:00099531330.110
positive regulation of cell differentiationGO:0045597640.108
positive regulation of signalingGO:00230562430.108
small molecule metabolic processGO:00442813050.108
actin cytoskeleton organizationGO:00300362060.108
cellular macromolecular complex assemblyGO:00346221530.104
developmental growthGO:00485892800.103
cell fate determinationGO:0001709910.103
camera type eye morphogenesisGO:004859320.101
positive regulation of neurogenesisGO:0050769410.100
negative regulation of developmental processGO:00510932010.100
anatomical structure homeostasisGO:0060249970.099
positive regulation of muscle organ developmentGO:004863660.098
larval developmentGO:00021641040.098
regulation of mitotic cell cycleGO:00073461900.096
regulation of growthGO:00400082330.095
positive regulation of phosphorylationGO:0042327870.094
skeletal muscle tissue developmentGO:0007519130.094
positive regulation of multicellular organismal processGO:00512401430.094
regulation of cell fate specificationGO:0042659270.092
extracellular structure organizationGO:0043062460.088
localization of cellGO:00516742570.088
gland morphogenesisGO:00226121450.087
epithelium migrationGO:00901321480.087
reproductive system developmentGO:0061458740.087
stem cell proliferationGO:0072089880.087
determination of bilateral symmetryGO:0009855130.086
regulation of multicellular organism growthGO:0040014400.086
positive regulation of growthGO:0045927750.085
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.083
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.082
stem cell divisionGO:0017145690.081
cell junction organizationGO:0034330570.081
kidney developmentGO:000182230.081
homeostatic processGO:00425921990.080
embryonic axis specificationGO:00005781070.080
negative regulation of multicellular organismal processGO:00512411420.080
histone modificationGO:00165701060.080
photoreceptor cell fate commitmentGO:0046552410.080
regulation of intracellular signal transductionGO:19025312360.079
anterior posterior axis specification embryoGO:00085951030.079
neuron fate determinationGO:004866410.078
cell deathGO:00082192790.078
eye antennal disc morphogenesisGO:0007455340.077
positive regulation of lipid metabolic processGO:004583440.075
nephron epithelium developmentGO:007200930.075
organelle fissionGO:00482853400.075
ovarian follicle cell migrationGO:00072971210.074
mapk cascadeGO:00001651070.074
hemopoiesisGO:0030097460.073
reproductive structure developmentGO:0048608740.073
regulation of programmed cell deathGO:00430671520.073
positive regulation of cell developmentGO:0010720610.071
regulation of cell deathGO:00109411730.070
cellular response to growth factor stimulusGO:0071363300.070
protein phosphorylationGO:00064681690.069
mesoderm formationGO:0001707210.069
macromolecular complex assemblyGO:00650032560.069
reproductive behaviorGO:00190981220.068
gastrulation involving germ band extensionGO:0010004360.068
cell divisionGO:00513012480.068
defense responseGO:00069523000.067
positive regulation of cellular protein metabolic processGO:00322701180.067
protein importGO:0017038550.066
embryonic development via the syncytial blastodermGO:00017001480.066
regulation of cell developmentGO:00602842150.066
hindgut developmentGO:0061525580.066
neuroblast fate determinationGO:0007400120.065
chromatin organizationGO:00063252070.065
mesenchyme developmentGO:006048590.065
chromosome organizationGO:00512763600.065
myoblast fusionGO:0007520430.065
wing disc morphogenesisGO:00074723440.065
regulation of organelle organizationGO:00330431960.065
muscle tissue morphogenesisGO:006041520.065
programmed cell deathGO:00125012570.064
kidney morphogenesisGO:006099330.064
cell type specific apoptotic processGO:0097285380.064
eye antennal disc developmentGO:0035214600.064
regulation of phosphorylationGO:00423251470.063
negative regulation of cell proliferationGO:0008285690.061
leg disc developmentGO:0035218920.061
regulation of bmp signaling pathwayGO:0030510230.061
negative regulation of cell cycle processGO:00109481090.060
chitin based cuticle developmentGO:0040003490.060
organelle assemblyGO:00709251980.059
muscle tissue developmentGO:0060537300.059
regulation of response to external stimulusGO:00321011150.059
embryo development ending in birth or egg hatchingGO:00097921520.059
Worm
limb developmentGO:006017310.059
nephrocyte differentiationGO:0061319120.059
regulation of mapk cascadeGO:0043408920.058
response to lipidGO:0033993380.058
nephron tubule developmentGO:007208030.057
single organism cellular localizationGO:19025801800.057
regulation of cellular amine metabolic processGO:003323830.056
positive regulation of nervous system developmentGO:0051962690.056
multicellular organismal reproductive behaviorGO:00330571100.055
outflow tract morphogenesisGO:000315140.054
epithelial cell developmentGO:00020642740.054
response to nitrogen compoundGO:1901698900.054
cellular response to oxygen containing compoundGO:1901701790.053
regulation of myoblast fusionGO:190173960.053
dna metabolic processGO:00062592270.053
covalent chromatin modificationGO:00165691060.052
developmental maturationGO:00217001720.052
regulation of phosphorus metabolic processGO:00511742100.052
regulation of notch signaling pathwayGO:00085931000.051
locomotory behaviorGO:00076261760.051
regulation of cardioblast differentiationGO:005189090.051
cellular response to hormone stimulusGO:0032870440.050
notch signaling pathwayGO:00072191200.050
skeletal muscle organ developmentGO:0060538480.050
positive regulation of protein modification processGO:0031401580.049
actomyosin structure organizationGO:0031032560.049
mesenchymal cell developmentGO:001403110.049
carboxylic acid metabolic processGO:0019752920.049
small molecule biosynthetic processGO:0044283370.048
ketone biosynthetic processGO:0042181160.048
regulation of steroid metabolic processGO:001921820.047
proteolysisGO:00065081920.047
salivary gland cell autophagic cell deathGO:0035071830.047
peptidyl amino acid modificationGO:00181931050.047
striated muscle tissue developmentGO:0014706270.047
determination of left right symmetryGO:000736890.047
embryonic organ morphogenesisGO:004856250.047
regulation of cell shapeGO:00083601130.046
actin filament based processGO:00300292200.045
negative regulation of cell cycleGO:00457861160.045
positive regulation of intracellular signal transductionGO:19025331160.045
formation of primary germ layerGO:0001704240.044
positive regulation of developmental growthGO:0048639620.044
sex differentiationGO:0007548810.044
regulation of phosphate metabolic processGO:00192202100.044
chorion containing eggshell pattern formationGO:0030381110.044
positive regulation of signal transductionGO:00099672230.043
renal tubule morphogenesisGO:0061333440.043
negative regulation of cell deathGO:0060548810.043
positive regulation of epithelial cell differentiationGO:003085810.043
nephron developmentGO:007200630.043
protein polymerizationGO:0051258420.043
regulation of stem cell proliferationGO:0072091400.042
response to sterolGO:0036314340.042
organonitrogen compound biosynthetic processGO:19015661170.042
cellular response to extracellular stimulusGO:0031668640.042
camera type eye developmentGO:004301040.042
intracellular signal transductionGO:00355563000.042
regulation of protein complex assemblyGO:0043254420.041
segment polarity determinationGO:0007367250.041
chitin based embryonic cuticle biosynthetic processGO:0008362160.041
regulation of epithelial cell differentiationGO:003085640.040
negative regulation of mitotic cell cycleGO:00459301090.040
cellular amino acid metabolic processGO:0006520610.039
innate immune responseGO:00450871440.039
imaginal disc derived wing vein specificationGO:0007474480.038
regulation of heart morphogenesisGO:200082630.038
morphogenesis of a branching epitheliumGO:0061138450.037
response to radiationGO:00093141550.037
positive regulation of cellular amine metabolic processGO:003324000.037
cellular catabolic processGO:00442483720.037
signal transduction by phosphorylationGO:00230141070.037
forebrain developmentGO:003090020.036
wing disc pattern formationGO:0035222660.036
positive regulation of protein metabolic processGO:00512471280.036
single organism biosynthetic processGO:00447112060.036
positive regulation of phosphate metabolic processGO:00459371390.035
negative regulation of molecular functionGO:0044092510.034
limb morphogenesisGO:003510810.034
cuticle developmentGO:0042335860.034
cellular response to nutrient levelsGO:0031669620.034
negative regulation of apoptotic processGO:0043066630.034
chromatin silencingGO:0006342760.034
positive regulation of cell deathGO:0010942690.034
oocyte developmentGO:00485991240.034
multi organism behaviorGO:00517051750.034
response to woundingGO:0009611940.033
cell recognitionGO:00080371020.033
steroid biosynthetic processGO:0006694160.032
regulation of cell projection organizationGO:0031344920.032
positive regulation of phosphorus metabolic processGO:00105621390.032
developmental programmed cell deathGO:00106231380.032
regulation of lipid metabolic processGO:0019216150.032
regulation of epithelial cell proliferationGO:005067840.032
establishment or maintenance of cell polarityGO:00071631670.032
actin filament organizationGO:00070151260.031
regulation of cell morphogenesisGO:00226041630.031
negative regulation of programmed cell deathGO:0043069720.031
negative regulation of response to stimulusGO:00485852580.031
regulation of cell cycleGO:00517262910.031
multicellular organismal homeostasisGO:0048871410.031
regulation of cellular component movementGO:0051270420.030
extracellular matrix organizationGO:0030198320.030
regulation of cytoskeleton organizationGO:0051493890.030
axis specificationGO:00097981670.030
gliogenesisGO:0042063800.030
regulation of cell cycle processGO:00105641810.030
muscle fiber developmentGO:0048747120.030
regulation of cellular localizationGO:00603411360.030
imaginal disc pattern formationGO:0007447910.029
pharynx developmentGO:006046510.029
response to other organismGO:00517072930.029
cellular response to starvationGO:0009267610.029
regulation of protein polymerizationGO:0032271280.029
synapse organizationGO:00508081960.029
positive regulation of response to external stimulusGO:0032103440.029
regulation of catalytic activityGO:00507901850.029
blood circulationGO:0008015260.028
negative regulation of organelle organizationGO:0010639560.028
cellular response to fibroblast growth factor stimulusGO:0044344100.028
cellular protein localizationGO:00346131600.028
r7 cell differentiationGO:0045466430.028
vesicle mediated transportGO:00161923810.028
regulation of response to stressGO:00801342000.027
endodermal cell differentiationGO:003598730.027
intracellular receptor signaling pathwayGO:0030522190.027
epidermal growth factor receptor signaling pathwayGO:0007173580.027
protein maturationGO:0051604710.027
extracellular matrix assemblyGO:0085029130.026
cellular response to lipidGO:0071396200.026
oocyte axis specificationGO:00073091080.026
specification of symmetryGO:0009799130.026
dorsal closureGO:0007391790.026
retina development in camera type eyeGO:006004140.026
hemocyte differentiationGO:0042386380.026
negative regulation of cell fate commitmentGO:0010454170.026
organonitrogen compound metabolic processGO:19015643180.026
syncytium formation by plasma membrane fusionGO:0000768430.025
positive regulation of organelle organizationGO:0010638650.025
muscle organ developmentGO:00075171270.025
embryonic hemopoiesisGO:0035162260.025
establishment of localization in cellGO:00516494020.025
leg disc morphogenesisGO:0007478800.025
lipid metabolic processGO:00066291210.025
axonal defasciculationGO:0007414120.025
establishment of protein localizationGO:00451841630.024
response to hormoneGO:0009725450.024
renal filtration cell differentiationGO:0061318120.024
locomotor rhythmGO:0045475560.024
regulation of stem cell differentiationGO:2000736140.024
regulation of cellular component biogenesisGO:00440872010.024
mesodermal cell fate commitmentGO:000171070.024
developmental pigmentationGO:0048066680.023
response to nutrient levelsGO:00316671140.023
organic substance transportGO:00717022570.023
regulation of cellular amino acid metabolic processGO:000652100.023
regulation of nucleocytoplasmic transportGO:0046822350.023
formation of organ boundaryGO:0010160300.023
regulation of anatomical structure sizeGO:00900661630.023
photoreceptor cell developmentGO:0042461960.022
protein transportGO:00150311550.022
eggshell formationGO:00307031050.022
r8 cell fate commitmentGO:000746060.022
negative regulation of cytoskeleton organizationGO:0051494300.022
positive regulation of cellular amino acid metabolic processGO:004576400.022
regulation of protein phosphorylationGO:0001932640.022
regulation of striated muscle cell differentiationGO:005115380.022
catabolic processGO:00090564090.022
regulation of cell sizeGO:0008361630.022
positive regulation of cell projection organizationGO:0031346290.021
response to extracellular stimulusGO:00099911160.021
cell growthGO:00160491080.021
stem cell fate commitmentGO:0048865250.021
negative regulation of immune system processGO:0002683500.021
regulation of localizationGO:00328792750.021
nuclear transportGO:0051169720.021
axon midline choice point recognitionGO:0016199260.021
multi multicellular organism processGO:00447061230.021
histolysisGO:00075591020.021
cell projection assemblyGO:0030031940.021
retinal ganglion cell axon guidanceGO:0031290120.021
cellular response to dna damage stimulusGO:00069742230.021
positive regulation of mapk cascadeGO:0043410630.021
regulation of neuron projection developmentGO:0010975690.021
single organism intracellular transportGO:19025822070.020
positive regulation of erk1 and erk2 cascadeGO:0070374360.020
cilium assemblyGO:0042384380.020
response to biotic stimulusGO:00096072940.020
neural precursor cell proliferationGO:0061351750.020
head segmentationGO:0035287130.020
nuclear divisionGO:00002803320.020
neuroepithelial cell differentiationGO:006056360.020
imaginal disc derived leg morphogenesisGO:0007480800.020
hematopoietic progenitor cell differentiationGO:000224410.019
oocyte constructionGO:00073081120.019
wound healingGO:0042060750.019

eve disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.104
musculoskeletal system diseaseDOID:1700.104
organ system cancerDOID:005068600.081
cancerDOID:16200.081
disease of cellular proliferationDOID:1456600.081
waardenburg s syndromeDOID:925800.051
connective tissue diseaseDOID:6500.040
bone diseaseDOID:008000100.040
musculoskeletal system cancerDOID:006010000.034