IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

CG12057 (Dmel_CG12057)

CG12057 gene product from transcript CG12057-RA

(Aliases: Dmel\CG12057,BcDNA:LP05863)

FLYBASE: FBgn0030098
Entrez: 31854
UniProtKB: Q9W377

Process Predictions
Disease Predictions

CG12057 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
positive regulation of response to stimulus	GO:0048584	323	0.152
defense response to other organism	GO:0098542	225	0.105
immune system process	GO:0002376	347	0.104
innate immune response	GO:0045087	144	0.102
response to other organism	GO:0051707	293	0.101
sterol homeostasis	GO:0055092	4	0.093
immune response	GO:0006955	246	0.090
response to external biotic stimulus	GO:0043207	293	0.087
positive regulation of cell communication	GO:0010647	250	0.072
defense response to fungus	GO:0050832	48	0.066
toll signaling pathway	GO:0008063	25	0.066
defense response	GO:0006952	300	0.063
small molecule metabolic process	GO:0044281	305	0.061
cholesterol transport	GO:0030301	2	0.060
response to bacterium	GO:0009617	198	0.055
positive regulation of signaling	GO:0023056	243	0.054
response to fungus	GO:0009620	50	0.052
organic acid metabolic process	GO:0006082	103	0.045
regulation of multicellular organismal development	GO:2000026	414	0.045
defense response to bacterium	GO:0042742	178	0.043
defense response to gram negative bacterium	GO:0050829	94	0.042
endocytosis	GO:0006897	310	0.040
body morphogenesis	GO:0010171	2	0.039
growth	GO:0040007	359	0.039
carboxylic acid metabolic process	GO:0019752	92	0.039
appendage development	GO:0048736	401	0.037
positive regulation of signal transduction	GO:0009967	223	0.035
single organism biosynthetic process	GO:0044711	206	0.035
organonitrogen compound metabolic process	GO:1901564	318	0.034
homeostatic process	GO:0042592	199	0.033
triglyceride catabolic process	GO:0019433	3	0.033
multi organism behavior	GO:0051705	175	0.033
response to abiotic stimulus	GO:0009628	341	0.032
protein modification process	GO:0036211	438	0.032
developmental growth	GO:0048589	280	0.031
cholesterol homeostasis	GO:0042632	3	0.030
acylglycerol biosynthetic process	GO:0046463	2	0.030
lipid homeostasis	GO:0055088	33	0.030
phospholipid homeostasis	GO:0055091	1	0.029
imaginal disc derived wing morphogenesis	GO:0007476	337	0.029
post embryonic appendage morphogenesis	GO:0035120	385	0.029
gland development	GO:0048732	191	0.028
appendage morphogenesis	GO:0035107	397	0.028
cellular amino acid metabolic process	GO:0006520	61	0.026
cellular catabolic process	GO:0044248	372	0.025
phagocytosis	GO:0006909	215	0.025
regulation of developmental growth	GO:0048638	174	0.025
cell proliferation	GO:0008283	299	0.024
vesicle mediated transport	GO:0016192	381	0.024
cellular protein modification process	GO:0006464	438	0.024
cellular amine metabolic process	GO:0044106	12	0.024
respiratory system development	GO:0060541	213	0.023
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.023
phosphatidic acid metabolic process	GO:0046473	1	0.022
intracellular signal transduction	GO:0035556	300	0.022
amine metabolic process	GO:0009308	12	0.022
negative regulation of response to stimulus	GO:0048585	258	0.021
multi organism reproductive behavior	GO:0044705	121	0.021
activation of innate immune response	GO:0002218	4	0.021
salivary gland morphogenesis	GO:0007435	145	0.021
extracellular structure organization	GO:0043062	46	0.020
regulation of localization	GO:0032879	275	0.020
cell recognition	GO:0008037	102	0.020
death	GO:0016265	284	0.020
oxoacid metabolic process	GO:0043436	103	0.020
wing disc morphogenesis	GO:0007472	344	0.020
regulation of transport	GO:0051049	181	0.020
macromolecular complex assembly	GO:0065003	256	0.019
carbohydrate derivative metabolic process	GO:1901135	217	0.019
lipid metabolic process	GO:0006629	121	0.019
response to copper ion	GO:0046688	4	0.019
imaginal disc derived appendage development	GO:0048737	399	0.019
regulation of growth	GO:0040008	233	0.018
negative regulation of signaling	GO:0023057	219	0.018
response to biotic stimulus	GO:0009607	294	0.018
phosphorylation	GO:0016310	294	0.017
cell growth	GO:0016049	108	0.017
regulation of cellular ketone metabolic process	GO:0010565	3	0.016
negative regulation of cellular metabolic process	GO:0031324	382	0.016
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.016
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.016
protein complex assembly	GO:0006461	200	0.016
regulation of cellular amino acid metabolic process	GO:0006521	0	0.016
regulation of cellular amine metabolic process	GO:0033238	3	0.016
negative regulation of cell differentiation	GO:0045596	143	0.016
regionalization	GO:0003002	416	0.016
exocrine system development	GO:0035272	162	0.015
chemical homeostasis	GO:0048878	92	0.015
regulation of response to stress	GO:0080134	200	0.015
organic substance transport	GO:0071702	257	0.015
lipid localization	GO:0010876	54	0.015
reproductive behavior	GO:0019098	122	0.015
muscle tissue development	GO:0060537	30	0.015
organic substance catabolic process	GO:1901575	308	0.015
phosphatidylethanolamine metabolic process	GO:0046337	1	0.014
catabolic process	GO:0009056	409	0.014
negative regulation of gene expression	GO:0010629	387	0.014
peptidoglycan recognition protein signaling pathway	GO:0061057	16	0.014
lipid biosynthetic process	GO:0008610	46	0.014
positive regulation of multicellular organismal process	GO:0051240	143	0.014
regulation of phosphorus metabolic process	GO:0051174	210	0.014
alditol phosphate metabolic process	GO:0052646	2	0.014
ethanolamine containing compound metabolic process	GO:0042439	4	0.014
protein complex biogenesis	GO:0070271	201	0.014
negative regulation of biosynthetic process	GO:0009890	277	0.014
cell death	GO:0008219	279	0.014
mating	GO:0007618	120	0.014
programmed cell death	GO:0012501	257	0.013
response to organic substance	GO:0010033	284	0.013
regulation of cell cycle	GO:0051726	291	0.013
regulation of sequestering of triglyceride	GO:0010889	3	0.013
organophosphate metabolic process	GO:0019637	195	0.013
negative regulation of signal transduction	GO:0009968	206	0.013
mitotic nuclear division	GO:0007067	213	0.013
muscle organ development	GO:0007517	127	0.013
epithelial cell development	GO:0002064	274	0.013
very long chain fatty acid biosynthetic process	GO:0042761	2	0.013
female mating behavior	GO:0060180	30	0.013
forebrain development	GO:0030900	2	0.012
regulation of cell differentiation	GO:0045595	302	0.012
camera type eye development	GO:0043010	4	0.012
monocarboxylic acid metabolic process	GO:0032787	29	0.012
organophosphate catabolic process	GO:0046434	112	0.012
neutral lipid biosynthetic process	GO:0046460	2	0.012
developmental maturation	GO:0021700	172	0.012
neuron recognition	GO:0008038	101	0.012
pattern recognition receptor signaling pathway	GO:0002221	2	0.012
immune response activating signal transduction	GO:0002757	2	0.012
response to extracellular stimulus	GO:0009991	116	0.012
proteolysis	GO:0006508	192	0.012
salivary gland development	GO:0007431	162	0.012
segmentation	GO:0035282	207	0.012
cellular response to endogenous stimulus	GO:0071495	80	0.012
negative regulation of cell development	GO:0010721	62	0.012
copulation	GO:0007620	26	0.012
telencephalon development	GO:0021537	2	0.012
regulation of intracellular signal transduction	GO:1902531	236	0.012
cellular macromolecule localization	GO:0070727	220	0.012
innate immune response activating signal transduction	GO:0002758	2	0.012
regulation of phosphate metabolic process	GO:0019220	210	0.012
response to lipopolysaccharide	GO:0032496	4	0.011
negative regulation of developmental process	GO:0051093	201	0.011
long chain fatty acid metabolic process	GO:0001676	3	0.011
blastoderm segmentation	GO:0007350	159	0.011
regulation of organelle organization	GO:0033043	196	0.011
positive regulation of transport	GO:0051050	92	0.011
negative regulation of cell communication	GO:0010648	223	0.011
acylglycerol catabolic process	GO:0046464	3	0.011
connective tissue development	GO:0061448	3	0.011
salivary gland histolysis	GO:0035070	88	0.011
muscle structure development	GO:0061061	224	0.011
maintenance of location	GO:0051235	73	0.011
kidney development	GO:0001822	3	0.011
ion transport	GO:0006811	145	0.011
mating behavior	GO:0007617	106	0.011
muscle adaptation	GO:0043500	1	0.011
synapse organization	GO:0050808	196	0.011
regulation of lipid transport	GO:0032368	3	0.011
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.011
anatomical structure homeostasis	GO:0060249	97	0.011
cellular component assembly involved in morphogenesis	GO:0010927	151	0.010
single organism behavior	GO:0044708	391	0.010
cellular response to organic substance	GO:0071310	132	0.010
macromolecule catabolic process	GO:0009057	161	0.010
camera type eye morphogenesis	GO:0048593	2	0.010
neutral lipid metabolic process	GO:0006638	12	0.010
regulation of i kappab kinase nf kappab signaling	GO:0043122	2	0.010
cellular lipid metabolic process	GO:0044255	83	0.010
notch signaling pathway	GO:0007219	120	0.010
columnar cuboidal epithelial cell development	GO:0002066	249	0.010
translation	GO:0006412	69	0.010
transcription from rna polymerase ii promoter	GO:0006366	368	0.010
chromatin modification	GO:0016568	147	0.010
embryonic pattern specification	GO:0009880	174	0.010
compound eye development	GO:0048749	307	0.010
immune response regulating signaling pathway	GO:0002764	2	0.010
neutral lipid catabolic process	GO:0046461	3	0.010
positive regulation of biosynthetic process	GO:0009891	316	0.010

CG12057 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.055
disease of metabolism	DOID:0014667	0.053
carbohydrate metabolism disease	DOID:0050013	0.028
acquired metabolic disease	DOID:0060158	0.028
glucose metabolism disease	DOID:4194	0.028
inherited metabolic disorder	DOID:655	0.024
diabetes mellitus	DOID:9351	0.015
type 2 diabetes mellitus	DOID:9352	0.015
nervous system disease	DOID:863	0.014
familial hyperlipidemia	DOID:1168	0.012
lipid metabolism disorder	DOID:3146	0.012
sensory system disease	DOID:0050155	0.010

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