Drosophila melanogaster

49 known processes

HP6 (Dmel_CG15636)

Heterochromatin protein 6

(Aliases: Umbrea,Dmel\CG15636,umbrea,CG15636)

HP6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
chromosome organizationGO:00512763600.460
homeostatic processGO:00425921990.143
mitotic nuclear divisionGO:00070672130.132
telomere organizationGO:0032200210.111
positive regulation of nitrogen compound metabolic processGO:00511733540.101
Fly
positive regulation of nucleic acid templated transcriptionGO:19035082660.088
positive regulation of rna metabolic processGO:00512542710.081
positive regulation of rna biosynthetic processGO:19026802660.080
positive regulation of transcription dna templatedGO:00458932660.069
positive regulation of biosynthetic processGO:00098913160.062
regulation of multicellular organismal developmentGO:20000264140.059
determination of adult lifespanGO:00083401370.057
positive regulation of cellular biosynthetic processGO:00313283160.056
deathGO:00162652840.056
Fly
positive regulation of response to stimulusGO:00485843230.052
transcription from rna polymerase ii promoterGO:00063663680.051
endocytosisGO:00068973100.051
positive regulation of macromolecule metabolic processGO:00106044050.049
Fly
cellular response to dna damage stimulusGO:00069742230.049
positive regulation of nucleobase containing compound metabolic processGO:00459353320.047
Fly
protein modification processGO:00362114380.047
Fly
dna metabolic processGO:00062592270.047
negative regulation of biosynthetic processGO:00098902770.046
Fly
regulation of nervous system developmentGO:00519602480.046
negative regulation of developmental processGO:00510932010.045
morphogenesis of an epitheliumGO:00020092760.044
exocrine system developmentGO:00352721620.044
catabolic processGO:00090564090.043
sister chromatid segregationGO:0000819920.041
negative regulation of signalingGO:00230572190.041
cellular protein modification processGO:00064644380.041
Fly
chromatin modificationGO:00165681470.040
Fly
positive regulation of signalingGO:00230562430.040
sleepGO:0030431490.038
salivary gland developmentGO:00074311620.038
vesicle mediated transportGO:00161923810.038
multicellular organismal agingGO:00102591400.038
histone modificationGO:00165701060.037
Fly
neurological system processGO:00508773580.037
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.037
positive regulation of signal transductionGO:00099672230.037
chromatin organizationGO:00063252070.036
Fly
body morphogenesisGO:001017120.036
regulation of neurogenesisGO:00507671580.036
negative regulation of gene expressionGO:00106293870.035
Fly
positive regulation of cell communicationGO:00106472500.034
proteolysisGO:00065081920.034
telomere maintenanceGO:0000723210.034
protein catabolic processGO:00301631010.034
regulation of programmed cell deathGO:00430671520.033
Fly
negative regulation of cellular metabolic processGO:00313243820.033
Fly
regulation of organelle organizationGO:00330431960.033
Fly
regulation of transcription from rna polymerase ii promoterGO:00063573780.032
dendrite developmentGO:00163582040.032
regulation of cell deathGO:00109411730.031
Fly
regulation of neuron differentiationGO:00456641030.031
positive regulation of macromolecule biosynthetic processGO:00105572830.030
organelle fissionGO:00482853400.030
negative regulation of macromolecule biosynthetic processGO:00105582700.030
Fly
positive regulation of developmental processGO:00510941430.030
protein localizationGO:00081042840.030
anatomical structure homeostasisGO:0060249970.030
regulation of anatomical structure morphogenesisGO:00226032420.030
regulation of cellular protein metabolic processGO:00322682430.029
Fly
regulation of cell differentiationGO:00455953020.029
regulation of growthGO:00400082330.029
negative regulation of response to stimulusGO:00485852580.029
regulation of developmental growthGO:00486381740.028
cognitionGO:00508901410.028
negative regulation of nucleobase containing compound metabolic processGO:00459342610.028
Fly
cell deathGO:00082192790.027
Fly
organic substance catabolic processGO:19015753080.027
covalent chromatin modificationGO:00165691060.027
Fly
developmental growthGO:00485892800.027
salivary gland morphogenesisGO:00074351450.026
gland developmentGO:00487321910.026
nuclear divisionGO:00002803320.026
cell cell signaling involved in cell fate commitmentGO:00451682100.026
forebrain developmentGO:003090020.025
macromolecule catabolic processGO:00090571610.024
regulation of cellular amine metabolic processGO:003323830.024
negative regulation of multicellular organismal processGO:00512411420.024
negative regulation of nitrogen compound metabolic processGO:00511722650.024
Fly
negative regulation of cell communicationGO:00106482230.024
regulation of cell developmentGO:00602842150.024
dna conformation changeGO:00711031050.024
Fly
telomere cappingGO:0016233110.024
regionalizationGO:00030024160.024
developmental maturationGO:00217001720.024
agingGO:00075681430.023
regulation of intracellular signal transductionGO:19025312360.023
regulation of protein metabolic processGO:00512462560.023
Fly
phagocytosisGO:00069092150.023
intracellular transportGO:00469072280.023
cellular response to chemical stimulusGO:00708871990.023
regulation of cell cycle processGO:00105641810.023
positive regulation of gene expressionGO:00106282900.023
g protein coupled receptor signaling pathwayGO:00071861360.023
chemical homeostasisGO:0048878920.023
small gtpase mediated signal transductionGO:0007264880.023
negative regulation of signal transductionGO:00099682060.022
regulation of phosphate metabolic processGO:00192202100.022
single organism behaviorGO:00447083910.022
positive regulation of cellular amino acid metabolic processGO:004576400.022
regulation of cellular component biogenesisGO:00440872010.022
Fly
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.022
spindle organizationGO:00070512530.022
somatic muscle developmentGO:0007525660.021
cholesterol homeostasisGO:004263230.021
regulation of phosphorus metabolic processGO:00511742100.021
oxoacid metabolic processGO:00434361030.021
developmental programmed cell deathGO:00106231380.020
response to oxidative stressGO:0006979860.020
regulation of apoptotic processGO:00429811300.020
Fly
mitotic spindle organizationGO:00070522200.020
multi multicellular organism processGO:00447061230.020
regulation of organ growthGO:0046620420.020
phosphorylationGO:00163102940.019
gland morphogenesisGO:00226121450.019
ras protein signal transductionGO:0007265880.019
enzyme linked receptor protein signaling pathwayGO:00071671790.019
protein phosphorylationGO:00064681690.019
chromosome segregationGO:00070591570.019
programmed cell deathGO:00125012570.018
Fly
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.018
Fly
apoptotic processGO:00069151590.018
Fly
negative regulation of growthGO:0045926840.018
defense response to other organismGO:00985422250.018
dendrite morphogenesisGO:00488131990.018
compound eye developmentGO:00487493070.018
microtubule organizing center organizationGO:00310231680.018
spermatogenesisGO:00072832000.018
positive regulation of cellular amine metabolic processGO:003324000.018
intracellular signal transductionGO:00355563000.018
learningGO:0007612750.018
mitotic sister chromatid segregationGO:0000070870.018
negative regulation of nucleic acid templated transcriptionGO:19035072400.018
Fly
negative regulation of developmental growthGO:0048640640.018
growthGO:00400073590.018
tissue morphogenesisGO:00487292970.018
salivary gland cell autophagic cell deathGO:0035071830.018
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.018
regulation of cell cycleGO:00517262910.018
kidney developmentGO:000182230.017
positive regulation of cellular component biogenesisGO:0044089800.017
Fly
regulation of organ morphogenesisGO:2000027780.017
centrosome cycleGO:00070981370.017
carboxylic acid metabolic processGO:0019752920.017
negative regulation of cell differentiationGO:00455961430.017
organ growthGO:0035265560.017
regulation of ras protein signal transductionGO:0046578930.017
cytoplasmic transportGO:00164821300.017
hindbrain developmentGO:003090220.017
response to other organismGO:00517072930.017
cellular catabolic processGO:00442483720.017
response to abiotic stimulusGO:00096283410.016
intracellular protein transportGO:00068861040.016
neural retina developmentGO:000340740.016
regulation of response to stressGO:00801342000.016
organic acid metabolic processGO:00060821030.016
organelle assemblyGO:00709251980.016
organonitrogen compound metabolic processGO:19015643180.016
cellular macromolecular complex assemblyGO:00346221530.016
regulation of transportGO:00510491810.016
amine metabolic processGO:0009308120.016
appendage developmentGO:00487364010.016
response to bacteriumGO:00096171980.016
regulation of catalytic activityGO:00507901850.016
stem cell differentiationGO:00488631170.016
camera type eye developmentGO:004301040.016
regulation of epithelial cell differentiationGO:003085640.016
salivary gland histolysisGO:0035070880.015
histolysisGO:00075591020.015
synapse assemblyGO:00074161430.015
negative regulation of nervous system developmentGO:0051961920.015
locomotory behaviorGO:00076261760.015
eye developmentGO:00016543230.015
mapk cascadeGO:00001651070.015
telencephalon developmentGO:002153720.015
establishment of localization in cellGO:00516494020.015
positive regulation of nervous system developmentGO:0051962690.015
regulation of localizationGO:00328792750.015
negative regulation of cell cycleGO:00457861160.015
wing disc morphogenesisGO:00074723440.015
photoreceptor cell differentiationGO:00465301700.015
posttranscriptional regulation of gene expressionGO:00106081450.015
regulation of cell cycle phase transitionGO:19019871300.015
peptidyl amino acid modificationGO:00181931050.015
Fly
single organism intracellular transportGO:19025822070.015
cation transmembrane transportGO:0098655880.014
establishment of protein localizationGO:00451841630.014
signal transduction by phosphorylationGO:00230141070.014
defense response to bacteriumGO:00427421780.014
regulation of cellular localizationGO:00603411360.014
cellular protein localizationGO:00346131600.014
sensory perceptionGO:00076001960.014
negative regulation of cellular biosynthetic processGO:00313272770.014
Fly
positive regulation of multicellular organismal processGO:00512401430.014
centrosome duplicationGO:00512981210.014
cellular amino acid metabolic processGO:0006520610.014
axon developmentGO:00615642970.014
notch signaling pathwayGO:00072191200.014
regulation of small gtpase mediated signal transductionGO:0051056930.014
chromatin remodelingGO:0006338720.014
Fly
rna processingGO:00063961470.014
protein modification by small protein conjugation or removalGO:00706471060.014
nuclear transportGO:0051169720.014
compound eye morphogenesisGO:00017452490.014
regulation of multi organism processGO:00439001310.014
regulation of cellular amino acid metabolic processGO:000652100.013
wnt signaling pathwayGO:0016055980.013
synapse organizationGO:00508081960.013
positive regulation of intracellular signal transductionGO:19025331160.013
regulation of phosphorylationGO:00423251470.013
cellular macromolecule localizationGO:00707272200.013
post embryonic appendage morphogenesisGO:00351203850.013
aromatic compound catabolic processGO:00194391660.013
regulation of protein localizationGO:0032880760.013
inseminationGO:0007320220.013
matingGO:00076181200.013
retina development in camera type eyeGO:006004140.013
cellular modified amino acid metabolic processGO:0006575450.013
small molecule metabolic processGO:00442813050.013
posttranscriptional gene silencing by rnaGO:0035194450.013
response to oxygen containing compoundGO:19017002000.013
regulation of notch signaling pathwayGO:00085931000.013
negative regulation of protein metabolic processGO:0051248850.013
regulation of intracellular transportGO:0032386640.013
rrna processingGO:000636430.013
germline stem cell asymmetric divisionGO:0098728150.013
organic substance transportGO:00717022570.013
axis specificationGO:00097981670.013
multicellular organism growthGO:0035264460.013
regulation of dendrite developmentGO:0050773370.013
chemotaxisGO:00069352490.012
nucleocytoplasmic transportGO:0006913720.012
cellular amine metabolic processGO:0044106120.012
axonogenesisGO:00074092900.012
regulation of reproductive processGO:2000241540.012
larval behaviorGO:0030537420.012
regulation of embryonic developmentGO:0045995680.012
microtubule cytoskeleton organization involved in mitosisGO:1902850520.012
stress activated mapk cascadeGO:0051403520.012
embryonic morphogenesisGO:00485982060.012
single organismal cell cell adhesionGO:0016337450.012
response to biotic stimulusGO:00096072940.012
regulation of defense responseGO:00313471020.012
taxisGO:00423303040.012
regulation of cellular ketone metabolic processGO:001056530.012
tube morphogenesisGO:00352391910.012
positive regulation of phosphorus metabolic processGO:00105621390.012
sterol homeostasisGO:005509240.012
regulation of response to external stimulusGO:00321011150.011
cellular response to organic substanceGO:00713101320.011
proteolysis involved in cellular protein catabolic processGO:0051603830.011
single organism cellular localizationGO:19025801800.011
negative regulation of gene expression epigeneticGO:0045814770.011
Fly
negative regulation of transcription dna templatedGO:00458922370.011
Fly
protein processingGO:0016485680.011
cell cycle checkpointGO:0000075950.011
regulation of behaviorGO:0050795750.011
appendage morphogenesisGO:00351073970.011
cell fate determinationGO:0001709910.011
regulation of mapk cascadeGO:0043408920.011
tube developmentGO:00352952440.011
protein modification by small protein conjugationGO:0032446790.011
regulation of molecular functionGO:00650092170.011
cation transportGO:00068121100.011
muscle structure developmentGO:00610612240.011
regulation of heart contractionGO:0008016210.011
lipid metabolic processGO:00066291210.011
eye morphogenesisGO:00485922600.011
translationGO:0006412690.011
regulation of cell morphogenesisGO:00226041630.011
positive regulation of molecular functionGO:00440931360.011
dna alkylationGO:000630540.011
Fly
negative regulation of cell developmentGO:0010721620.011
positive regulation of cellular protein metabolic processGO:00322701180.011
Fly
monocarboxylic acid transportGO:001571830.011
sensory organ morphogenesisGO:00905962600.011
eye photoreceptor cell differentiationGO:00017541450.011
organonitrogen compound biosynthetic processGO:19015661170.010
anterior posterior pattern specificationGO:00099521360.010
endomembrane system organizationGO:00102561190.010
male gamete generationGO:00482322010.010
microtubule based movementGO:0007018510.010
cellular ketone metabolic processGO:0042180240.010
regulation of immune system processGO:00026821760.010
autophagic cell deathGO:0048102830.010
cell divisionGO:00513012480.010
regulation of neuron projection developmentGO:0010975690.010
positive regulation of hydrolase activityGO:0051345780.010
positive regulation of cell motilityGO:200014730.010
spindle assembly involved in mitosisGO:0090307500.010
adult locomotory behaviorGO:0008344760.010
positive regulation of protein metabolic processGO:00512471280.010
Fly
mesenchymal cell developmentGO:001403110.010
epithelial tube morphogenesisGO:0060562880.010
response to organic substanceGO:00100332840.010
regulation of mitotic cell cycleGO:00073461900.010
protein dna complex subunit organizationGO:0071824860.010
jnk cascadeGO:0007254500.010

HP6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.017
nervous system diseaseDOID:86300.014