Drosophila melanogaster

30 known processes

HBS1 (Dmel_CG1898)

CG1898 gene product from transcript CG1898-RA

(Aliases: CG1898,hbs1,Dmel\CG1898)

HBS1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of response to stimulusGO:00485843230.060
regulation of protein metabolic processGO:00512462560.054
chromatin modificationGO:00165681470.053
protein modification processGO:00362114380.051
protein dna complex subunit organizationGO:0071824860.050
cellular protein catabolic processGO:0044257830.050
histone modificationGO:00165701060.044
intracellular transportGO:00469072280.042
positive regulation of signalingGO:00230562430.041
covalent chromatin modificationGO:00165691060.040
chromosome organizationGO:00512763600.038
regulation of cellular component biogenesisGO:00440872010.038
chromatin organizationGO:00063252070.037
small molecule metabolic processGO:00442813050.037
homeostatic processGO:00425921990.036
protein acetylationGO:0006473390.036
organonitrogen compound metabolic processGO:19015643180.036
proteolysisGO:00065081920.036
response to external biotic stimulusGO:00432072930.036
dna metabolic processGO:00062592270.036
response to biotic stimulusGO:00096072940.035
intracellular signal transductionGO:00355563000.035
regionalizationGO:00030024160.034
positive regulation of cell communicationGO:00106472500.034
regulation of organelle organizationGO:00330431960.034
eye developmentGO:00016543230.033
organic substance catabolic processGO:19015753080.033
transcription from rna polymerase ii promoterGO:00063663680.033
vesicle mediated transportGO:00161923810.032
regulation of cellular catabolic processGO:00313291570.031
positive regulation of cellular biosynthetic processGO:00313283160.031
cellular catabolic processGO:00442483720.031
ubiquitin dependent protein catabolic processGO:0006511780.031
establishment of localization in cellGO:00516494020.031
regulation of cell cycleGO:00517262910.030
response to other organismGO:00517072930.030
immune system processGO:00023763470.029
eye morphogenesisGO:00485922600.029
catabolic processGO:00090564090.029
chromatin remodelingGO:0006338720.029
protein catabolic processGO:00301631010.028
actin filament based processGO:00300292200.028
regulation of intracellular signal transductionGO:19025312360.028
cellular macromolecule localizationGO:00707272200.028
macromolecule catabolic processGO:00090571610.027
compound eye morphogenesisGO:00017452490.026
response to lipopolysaccharideGO:003249640.026
regulation of mitotic cell cycleGO:00073461900.026
regulation of proteolysisGO:0030162870.026
segmentationGO:00352822070.026
mitotic nuclear divisionGO:00070672130.026
actin cytoskeleton organizationGO:00300362060.026
peptidyl amino acid modificationGO:00181931050.025
regulation of cellular ketone metabolic processGO:001056530.025
negative regulation of cell communicationGO:00106482230.025
regulation of protein catabolic processGO:0042176550.025
positive regulation of macromolecule metabolic processGO:00106044050.025
single organism intracellular transportGO:19025822070.025
phagocytosisGO:00069092150.025
regulation of response to stressGO:00801342000.025
regulation of immune system processGO:00026821760.025
actin filament organizationGO:00070151260.024
embryonic pattern specificationGO:00098801740.024
cellular macromolecule catabolic processGO:00442651360.024
tripartite regional subdivisionGO:00073511030.024
body morphogenesisGO:001017120.024
peptidyl lysine modificationGO:0018205570.024
regulation of multicellular organismal developmentGO:20000264140.024
negative regulation of gene expressionGO:00106293870.023
protein complex biogenesisGO:00702712010.023
negative regulation of signalingGO:00230572190.023
regulation of phosphorus metabolic processGO:00511742100.023
cytoplasmic transportGO:00164821300.023
regulation of catabolic processGO:00098941700.023
internal protein amino acid acetylationGO:0006475380.023
positive regulation of nitrogen compound metabolic processGO:00511733540.023
positive regulation of protein metabolic processGO:00512471280.023
cellular protein modification processGO:00064644380.022
positive regulation of proteolysisGO:0045862520.022
regulation of cell cycle phase transitionGO:19019871300.022
single organism cellular localizationGO:19025801800.022
axis specificationGO:00097981670.022
immune responseGO:00069552460.022
purine ribonucleotide metabolic processGO:00091501450.022
transmembrane transportGO:00550851390.022
regulation of cell cycle processGO:00105641810.022
cell cycle phase transitionGO:00447701400.022
lateral inhibitionGO:00463312060.021
axonogenesisGO:00074092900.021
endocytosisGO:00068973100.021
defense response to other organismGO:00985422250.021
phosphorylationGO:00163102940.021
response to abiotic stimulusGO:00096283410.021
wing disc morphogenesisGO:00074723440.021
negative regulation of response to stimulusGO:00485852580.021
growthGO:00400073590.021
regulation of cell differentiationGO:00455953020.021
cellular response to chemical stimulusGO:00708871990.021
epithelial cell differentiationGO:00308553220.021
positive regulation of phosphate metabolic processGO:00459371390.021
compound eye developmentGO:00487493070.021
organophosphate metabolic processGO:00196371950.021
response to bacteriumGO:00096171980.020
positive regulation of signal transductionGO:00099672230.020
positive regulation of cellular component organizationGO:00511301560.020
proteolysis involved in cellular protein catabolic processGO:0051603830.020
defense response to bacteriumGO:00427421780.020
oxoacid metabolic processGO:00434361030.020
positive regulation of biosynthetic processGO:00098913160.020
organic substance transportGO:00717022570.020
modification dependent macromolecule catabolic processGO:0043632790.020
regulation of mapk cascadeGO:0043408920.020
ribonucleoside metabolic processGO:00091191270.020
cell divisionGO:00513012480.020
anterior posterior pattern specificationGO:00099521360.020
regulation of phosphate metabolic processGO:00192202100.020
innate immune responseGO:00450871440.020
nucleoside phosphate metabolic processGO:00067531620.020
mitotic cell cycle phase transitionGO:00447721380.019
single organism biosynthetic processGO:00447112060.019
positive regulation of cellular catabolic processGO:0031331950.019
carboxylic acid metabolic processGO:0019752920.019
imaginal disc derived wing morphogenesisGO:00074763370.019
nucleoside triphosphate metabolic processGO:00091411200.019
protein localizationGO:00081042840.019
positive regulation of molecular functionGO:00440931360.019
cellular homeostasisGO:0019725800.019
blastoderm segmentationGO:00073501590.019
regulation of mitotic cell cycle phase transitionGO:19019901300.019
cell cycle checkpointGO:0000075950.019
regulation of cellular amine metabolic processGO:003323830.019
nuclear divisionGO:00002803320.019
negative regulation of cell differentiationGO:00455961430.018
sensory organ morphogenesisGO:00905962600.018
regulation of cellular protein metabolic processGO:00322682430.018
nucleobase containing small molecule metabolic processGO:00550861740.018
cell deathGO:00082192790.018
protein complex assemblyGO:00064612000.018
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.018
pole plasm assemblyGO:0007315610.018
compound eye photoreceptor cell differentiationGO:00017511400.018
peptidyl lysine acetylationGO:0018394390.018
purine nucleotide metabolic processGO:00061631460.018
axon developmentGO:00615642970.018
oocyte differentiationGO:00099941450.018
regulation of molecular functionGO:00650092170.018
spindle organizationGO:00070512530.017
imaginal disc derived appendage morphogenesisGO:00351143950.017
cell cell signaling involved in cell fate commitmentGO:00451682100.017
organelle fissionGO:00482853400.017
photoreceptor cell differentiationGO:00465301700.017
immune response activating signal transductionGO:000275720.017
immune response regulating signaling pathwayGO:000276420.017
nucleotide metabolic processGO:00091171610.017
negative regulation of macromolecule biosynthetic processGO:00105582700.017
cellular response to dna damage stimulusGO:00069742230.017
anterior posterior axis specification embryoGO:00085951030.017
mitotic spindle organizationGO:00070522200.017
forebrain developmentGO:003090020.017
cell motilityGO:00488702510.017
small gtpase mediated signal transductionGO:0007264880.017
ras protein signal transductionGO:0007265880.017
negative regulation of nucleic acid templated transcriptionGO:19035072400.017
positive regulation of catalytic activityGO:00430851180.017
regulation of peptidase activityGO:0052547390.017
negative regulation of developmental processGO:00510932010.017
epithelial cell developmentGO:00020642740.017
wnt signaling pathwayGO:0016055980.017
negative regulation of cellular biosynthetic processGO:00313272770.017
imaginal disc derived appendage developmentGO:00487373990.016
negative regulation of cellular metabolic processGO:00313243820.016
regulation of cellular amino acid metabolic processGO:000652100.016
cellular amino acid metabolic processGO:0006520610.016
ovarian follicle cell developmentGO:00307072480.016
organic acid metabolic processGO:00060821030.016
modification dependent protein catabolic processGO:0019941780.016
positive regulation of intracellular signal transductionGO:19025331160.016
taxisGO:00423303040.016
negative regulation of signal transductionGO:00099682060.016
posttranscriptional regulation of gene expressionGO:00106081450.016
appendage morphogenesisGO:00351073970.016
spermatogenesisGO:00072832000.016
response to organic substanceGO:00100332840.016
embryonic axis specificationGO:00005781070.016
positive regulation of apoptotic signaling pathwayGO:200123540.016
camera type eye developmentGO:004301040.015
positive regulation of endopeptidase activityGO:0010950260.015
negative regulation of multicellular organismal processGO:00512411420.015
protein modification by small protein conjugation or removalGO:00706471060.015
mitotic dna damage checkpointGO:0044773740.015
regulation of immune responseGO:00507761180.015
positive regulation of phosphorus metabolic processGO:00105621390.015
positive regulation of catabolic processGO:00098961050.015
histone acetylationGO:0016573380.015
cell proliferationGO:00082832990.015
establishment of protein localizationGO:00451841630.015
negative regulation of cell cycle processGO:00109481090.015
anterior posterior axis specificationGO:00099481090.015
g2 dna damage checkpointGO:0031572690.015
mapk cascadeGO:00001651070.015
developmental growthGO:00485892800.015
chemotaxisGO:00069352490.015
nucleoside phosphate catabolic processGO:19012921100.014
nucleoside metabolic processGO:00091161270.014
purine nucleoside triphosphate catabolic processGO:00091461080.014
glycosyl compound metabolic processGO:19016571270.014
locomotory behaviorGO:00076261760.014
rna processingGO:00063961470.014
dephosphorylationGO:0016311510.014
negative regulation of mitotic cell cycle phase transitionGO:19019911030.014
cellular lipid metabolic processGO:0044255830.014
protein transportGO:00150311550.014
purine ribonucleoside metabolic processGO:00461281270.014
positive regulation of cellular protein metabolic processGO:00322701180.014
mesenchymal cell differentiationGO:004876210.014
negative regulation of cell cycle phase transitionGO:19019881030.014
protein acylationGO:0043543420.014
cellular nitrogen compound catabolic processGO:00442701650.014
single organism behaviorGO:00447083910.014
negative regulation of mitotic cell cycleGO:00459301090.014
protein maturationGO:0051604710.014
negative regulation of rna biosynthetic processGO:19026792400.014
regulation of localizationGO:00328792750.014
mitotic cell cycle checkpointGO:0007093880.014
purine nucleoside triphosphate metabolic processGO:00091441190.014
positive regulation of nucleobase containing compound metabolic processGO:00459353320.014
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.014
response to woundingGO:0009611940.014
appendage developmentGO:00487364010.014
aromatic compound catabolic processGO:00194391660.013
positive regulation of cysteine type endopeptidase activityGO:2001056240.013
neurological system processGO:00508773580.013
cellular amine metabolic processGO:0044106120.013
cellular protein localizationGO:00346131600.013
carbohydrate derivative catabolic processGO:19011361180.013
localization of cellGO:00516742570.013
purine ribonucleoside triphosphate metabolic processGO:00092051190.013
ribonucleotide metabolic processGO:00092591450.013
ribonucleoside triphosphate metabolic processGO:00091991190.013
respiratory system developmentGO:00605412130.013
telencephalon developmentGO:002153720.013
regulation of ras protein signal transductionGO:0046578930.013
multicellular organismal agingGO:00102591400.013
mitotic g2 m transition checkpointGO:0044818700.013
regulation of cell developmentGO:00602842150.013
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.013
negative regulation of cell cycleGO:00457861160.013
regulation of anatomical structure morphogenesisGO:00226032420.013
organic cyclic compound catabolic processGO:19013611680.013
dorsal ventral pattern formationGO:00099531330.013
cellular ketone metabolic processGO:0042180240.013
positive regulation of cell motilityGO:200014730.013
kidney developmentGO:000182230.013
tissue morphogenesisGO:00487292970.013
regulation of transcription from rna polymerase ii promoterGO:00063573780.013
developmental maturationGO:00217001720.013
oocyte anterior posterior axis specificationGO:0007314720.013
purine nucleoside catabolic processGO:00061521120.013
gene silencingGO:00164581380.013
ribose phosphate metabolic processGO:00196931450.013
negative regulation of nucleobase containing compound metabolic processGO:00459342610.013
anatomical structure homeostasisGO:0060249970.013
negative regulation of rna metabolic processGO:00512532510.013
negative regulation of protein metabolic processGO:0051248850.013
single organism catabolic processGO:00447122280.012
positive regulation of cellular component biogenesisGO:0044089800.012
response to oxygen containing compoundGO:19017002000.012
signal transduction by phosphorylationGO:00230141070.012
intracellular protein transportGO:00068861040.012
jak stat cascadeGO:0007259490.012
positive regulation of cellular amine metabolic processGO:003324000.012
oocyte constructionGO:00073081120.012
regulation of cellular localizationGO:00603411360.012
regulation of anatomical structure sizeGO:00900661630.012
oocyte axis specificationGO:00073091080.012
wound healingGO:0042060750.012
regulation of small gtpase mediated signal transductionGO:0051056930.012
morphogenesis of an epitheliumGO:00020092760.012
determination of adult lifespanGO:00083401370.012
proteasomal protein catabolic processGO:0010498590.012
positive regulation of cell migrationGO:003033520.012
regulation of epithelial cell proliferationGO:005067840.012
positive regulation of gene expressionGO:00106282900.012
connective tissue developmentGO:006144830.012
mitotic cytokinesisGO:0000281500.012
purine ribonucleoside catabolic processGO:00461301120.012
salivary gland developmentGO:00074311620.012
ribonucleoside catabolic processGO:00424541120.012
regulation of phosphorylationGO:00423251470.012
protein processingGO:0016485680.012
regulation of catalytic activityGO:00507901850.012
pole plasm mrna localizationGO:0019094490.012
guanosine containing compound metabolic processGO:1901068740.012
regulation of defense responseGO:00313471020.012
open tracheal system developmentGO:00074242040.012
embryo development ending in birth or egg hatchingGO:00097921520.012
eye photoreceptor cell differentiationGO:00017541450.012
intracellular mrna localization involved in pattern specification processGO:0060810560.012
organophosphate catabolic processGO:00464341120.012
mitotic dna integrity checkpointGO:0044774750.012
regulation of cellular protein catabolic processGO:1903362440.012
regulation of hydrolase activityGO:0051336970.012
cell growthGO:00160491080.012
purine nucleoside metabolic processGO:00422781270.012
ion transportGO:00068111450.011
regulation of cell deathGO:00109411730.011
programmed cell deathGO:00125012570.011
positive regulation of phosphorylationGO:0042327870.011
hematopoietic progenitor cell differentiationGO:000224410.011
heterocycle catabolic processGO:00467001660.011
negative regulation of biosynthetic processGO:00098902770.011
humoral immune responseGO:00069591170.011
histone exchangeGO:0043486210.011
positive regulation of macromolecule biosynthetic processGO:00105572830.011
negative regulation of cellular protein metabolic processGO:0032269850.011
post embryonic appendage morphogenesisGO:00351203850.011
columnar cuboidal epithelial cell developmentGO:00020662490.011
regulation of wnt signaling pathwayGO:0030111680.011
establishment or maintenance of cell polarityGO:00071631670.011
neuron projection guidanceGO:00974852410.011
positive regulation of defense responseGO:0031349590.011
positive regulation of protein catabolic processGO:0045732340.011
regulation of protein complex assemblyGO:0043254420.011
pole plasm oskar mrna localizationGO:0045451460.011
organonitrogen compound biosynthetic processGO:19015661170.011
regulation of response to external stimulusGO:00321011150.011
negative regulation of nervous system developmentGO:0051961920.011
positive regulation of immune responseGO:0050778630.011
cellular response to biotic stimulusGO:007121640.011
deathGO:00162652840.011
regulation of programmed cell deathGO:00430671520.011
dna integrity checkpointGO:0031570810.011
ribonucleotide catabolic processGO:00092611090.011
amine metabolic processGO:0009308120.011
regulation of cellular component sizeGO:0032535980.011
embryonic development via the syncytial blastodermGO:00017001480.011
macromolecular complex assemblyGO:00650032560.011
male gamete generationGO:00482322010.011
enzyme linked receptor protein signaling pathwayGO:00071671790.011
dorsal ventral axis specificationGO:0009950660.011
nucleobase containing compound catabolic processGO:00346551650.011
organonitrogen compound catabolic processGO:19015651280.011
negative regulation of epithelial cell proliferationGO:005068040.011
protein modification by small protein conjugationGO:0032446790.011
brain developmentGO:00074201200.011
regulation of innate immune responseGO:0045088710.011
adult behaviorGO:00305341370.010
cellular response to hexose stimulusGO:007133110.010
nucleoside catabolic processGO:00091641120.010
organophosphate biosynthetic processGO:0090407460.010
intracellular protein transmembrane importGO:004474340.010
positive regulation of hydrolase activityGO:0051345780.010
regulation of nervous system developmentGO:00519602480.010
rna 3 end processingGO:0031123450.010
purine ribonucleoside triphosphate catabolic processGO:00092071080.010
eye photoreceptor cell developmentGO:0042462810.010
regulation of autophagyGO:0010506620.010
myotube cell developmentGO:001490430.010
positive regulation of rna biosynthetic processGO:19026802660.010
dendrite morphogenesisGO:00488131990.010
mitotic g2 dna damage checkpointGO:0007095690.010
purine nucleoside monophosphate metabolic processGO:0009126500.010
cellular response to organic substanceGO:00713101320.010
purine ribonucleotide catabolic processGO:00091541090.010
negative regulation of nitrogen compound metabolic processGO:00511722650.010
positive regulation of organelle organizationGO:0010638650.010
cell adhesionGO:00071551360.010
spermatid developmentGO:0007286980.010
single organism membrane organizationGO:0044802930.010
atp dependent chromatin remodelingGO:0043044220.010
ion transmembrane transportGO:00342201220.010
maternal determination of anterior posterior axis embryoGO:0008358740.010
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.010
immune effector processGO:0002252980.010
autophagyGO:00069141080.010
mitotic sister chromatid segregationGO:0000070870.010
nucleoside phosphate biosynthetic processGO:1901293340.010
microtubule cytoskeleton organization involved in mitosisGO:1902850520.010
response to hexoseGO:000974630.010

HBS1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.047
nervous system diseaseDOID:86300.019
central nervous system diseaseDOID:33100.011
disease of metabolismDOID:001466700.011
inherited metabolic disorderDOID:65500.011
sensory system diseaseDOID:005015500.010