IMP: Integrative Multi-species Prediction

Drosophila melanogaster

192 known processes

WASp (Dmel_CG1520)

CG1520 gene product from transcript CG1520-RA

(Aliases: Wsp,WASP,wasp,CG1520,Dm WASP,Dmel\CG1520,wsp,D-WASP,dWASP,DmWASP,Wasp)

Entrez: 43402
FLYBASE: FBgn0024273
UniProtKB: Q86B74
UniProtKB: Q9VAT0

Process Predictions
Disease Predictions

WASp biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
regulation of synaptic growth at neuromuscular junction	GO:0008582	89	0.997
neuromuscular junction development	GO:0007528	149	0.994
syncytium formation by plasma membrane fusion	GO:0000768	43	0.991
developmental growth	GO:0048589	280	0.990
synaptic growth at neuromuscular junction	GO:0051124	119	0.987
myoblast fusion	GO:0007520	43	0.986
regulation of anatomical structure morphogenesis	GO:0022603	242	0.985
regulation of synapse assembly	GO:0051963	94	0.982
actin filament based process	GO:0030029	220	0.979
single organism membrane organization	GO:0044802	93	0.979	Human
actin cytoskeleton organization	GO:0030036	206	0.957
regulation of cell morphogenesis	GO:0022604	163	0.943
regulation of cellular component biogenesis	GO:0044087	201	0.937
regulation of neurogenesis	GO:0050767	158	0.930
actin filament organization	GO:0007015	126	0.928
regulation of cell projection organization	GO:0031344	92	0.918
regulation of actin cytoskeleton organization	GO:0032956	42	0.915
cell migration	GO:0016477	238	0.905	Zebrafish Worm
cell proliferation	GO:0008283	299	0.898
regulation of multicellular organismal development	GO:2000026	414	0.896
spermatid differentiation	GO:0048515	114	0.885
positive regulation of synaptic growth at neuromuscular junction	GO:0045887	26	0.877
axon development	GO:0061564	297	0.874
synapse assembly	GO:0007416	143	0.872
regulation of synapse structure and activity	GO:0050803	128	0.833
striated muscle cell differentiation	GO:0051146	90	0.830
endomembrane system organization	GO:0010256	119	0.829	Human
protein complex biogenesis	GO:0070271	201	0.823
eye photoreceptor cell differentiation	GO:0001754	145	0.819
negative regulation of cellular component organization	GO:0051129	108	0.815
epithelial cell differentiation	GO:0030855	322	0.794
regulation of nervous system development	GO:0051960	248	0.788
regulation of actin polymerization or depolymerization	GO:0008064	27	0.731
regulation of cytoskeleton organization	GO:0051493	89	0.726
regulation of synapse organization	GO:0050807	110	0.712
regulation of cell development	GO:0060284	215	0.706
appendage morphogenesis	GO:0035107	397	0.704
compound eye morphogenesis	GO:0001745	249	0.673
actin filament bundle assembly	GO:0051017	26	0.669	Yeast
purine containing compound catabolic process	GO:0072523	112	0.657
actin polymerization or depolymerization	GO:0008154	31	0.655
nucleoside catabolic process	GO:0009164	112	0.652
muscle cell differentiation	GO:0042692	103	0.650
regulation of actin filament polymerization	GO:0030833	25	0.646
tissue morphogenesis	GO:0048729	297	0.633	Worm
compound eye development	GO:0048749	307	0.632
negative regulation of cytoskeleton organization	GO:0051494	30	0.626
regulation of vesicle mediated transport	GO:0060627	59	0.625
spermatogenesis	GO:0007283	200	0.624
establishment of organelle localization	GO:0051656	122	0.611
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.610
regulation of anatomical structure size	GO:0090066	163	0.607
epithelial cell development	GO:0002064	274	0.607
vesicle mediated transport	GO:0016192	381	0.594
positive regulation of cellular component organization	GO:0051130	156	0.585
imaginal disc derived wing morphogenesis	GO:0007476	337	0.581
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.568
regulation of cell proliferation	GO:0042127	163	0.562
eye morphogenesis	GO:0048592	260	0.559
chaeta morphogenesis	GO:0008407	42	0.546
organelle fusion	GO:0048284	46	0.545
wing disc morphogenesis	GO:0007472	344	0.540
positive regulation of synapse assembly	GO:0051965	29	0.527
actin filament polymerization	GO:0030041	27	0.527
biological adhesion	GO:0022610	138	0.526
synapse organization	GO:0050808	196	0.514
regulation of phosphorus metabolic process	GO:0051174	210	0.498
regulation of actin filament based process	GO:0032970	42	0.484
regulation of synaptic transmission	GO:0050804	69	0.484
organophosphate metabolic process	GO:0019637	195	0.476
single organism intracellular transport	GO:1902582	207	0.471	Mouse
negative regulation of synaptic growth at neuromuscular junction	GO:0045886	39	0.466
organonitrogen compound metabolic process	GO:1901564	318	0.457
synaptic vesicle endocytosis	GO:0048488	28	0.442
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.439
neuron neuron synaptic transmission	GO:0007270	14	0.439
nucleoside triphosphate metabolic process	GO:0009141	120	0.438
myotube differentiation	GO:0014902	46	0.433
dendrite morphogenesis	GO:0048813	199	0.431
positive regulation of actin filament polymerization	GO:0030838	11	0.429
nucleoside phosphate catabolic process	GO:1901292	110	0.410
endocytosis	GO:0006897	310	0.402
regulation of epithelial cell proliferation	GO:0050678	4	0.395
synaptic transmission	GO:0007268	288	0.395
localization of cell	GO:0051674	257	0.384	Zebrafish Worm
eye development	GO:0001654	323	0.384
regulation of cellular protein metabolic process	GO:0032268	243	0.381
compound eye photoreceptor cell differentiation	GO:0001751	140	0.380
ribonucleoside metabolic process	GO:0009119	127	0.380
regulation of neuron differentiation	GO:0045664	103	0.376
dendrite development	GO:0016358	204	0.375
syncytium formation	GO:0006949	43	0.372
small molecule metabolic process	GO:0044281	305	0.365
death	GO:0016265	284	0.364
phosphorylation	GO:0016310	294	0.361
compound eye photoreceptor development	GO:0042051	78	0.356
lateral inhibition	GO:0046331	206	0.355
response to organic substance	GO:0010033	284	0.331
columnar cuboidal epithelial cell development	GO:0002066	249	0.329
adherens junction organization	GO:0034332	27	0.328
purine nucleotide catabolic process	GO:0006195	109	0.327
macromolecular complex assembly	GO:0065003	256	0.326
protein complex assembly	GO:0006461	200	0.325
spermatid development	GO:0007286	98	0.323
positive regulation of cell development	GO:0010720	61	0.322
tube development	GO:0035295	244	0.320
regulation of cell shape	GO:0008360	113	0.317
neuroblast proliferation	GO:0007405	74	0.316
purine ribonucleotide catabolic process	GO:0009154	109	0.314
synaptic vesicle recycling	GO:0036465	28	0.314
purine nucleoside catabolic process	GO:0006152	112	0.310
regulation of phosphorylation	GO:0042325	147	0.310
male gamete generation	GO:0048232	201	0.309
purine ribonucleoside metabolic process	GO:0046128	127	0.309
positive regulation of cellular component biogenesis	GO:0044089	80	0.308
ovarian follicle cell development	GO:0030707	248	0.307
ameboidal type cell migration	GO:0001667	151	0.302	Worm
regulation of cell differentiation	GO:0045595	302	0.302
regulation of filopodium assembly	GO:0051489	24	0.299
regulation of protein metabolic process	GO:0051246	256	0.297
branching morphogenesis of an epithelial tube	GO:0048754	45	0.296
positive regulation of developmental process	GO:0051094	143	0.289
cell motility	GO:0048870	251	0.287	Zebrafish Worm
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.287
membrane organization	GO:0061024	112	0.283
growth	GO:0040007	359	0.282
regulation of cell morphogenesis involved in differentiation	GO:0010769	61	0.281
eye photoreceptor cell development	GO:0042462	81	0.281
actin filament bundle organization	GO:0061572	28	0.281	Yeast
establishment of localization in cell	GO:0051649	402	0.274
organelle localization	GO:0051640	148	0.271	Mouse
multi organism behavior	GO:0051705	175	0.268
cellular catabolic process	GO:0044248	372	0.263
single organism membrane fusion	GO:0044801	42	0.257
embryonic development via the syncytial blastoderm	GO:0001700	148	0.257
nucleoside metabolic process	GO:0009116	127	0.256
regulation of actin filament length	GO:0030832	27	0.248
glycosyl compound catabolic process	GO:1901658	112	0.244
regulation of neuron projection development	GO:0010975	69	0.243
regulation of localization	GO:0032879	275	0.241	Zebrafish Mouse
axonogenesis	GO:0007409	290	0.239
purine ribonucleoside catabolic process	GO:0046130	112	0.237
synaptic vesicle transport	GO:0048489	50	0.235
cellular amine metabolic process	GO:0044106	12	0.233
positive regulation of nervous system development	GO:0051962	69	0.233
ribonucleotide metabolic process	GO:0009259	145	0.231
embryo development ending in birth or egg hatching	GO:0009792	152	0.224	Worm
organelle assembly	GO:0070925	198	0.219
single organism cellular localization	GO:1902580	180	0.218	Mouse
cell cell junction organization	GO:0045216	55	0.217
establishment of synaptic vesicle localization	GO:0097480	50	0.214
organonitrogen compound catabolic process	GO:1901565	128	0.212
appendage development	GO:0048736	401	0.212
locomotory behavior	GO:0007626	176	0.212
photoreceptor cell differentiation	GO:0046530	170	0.210
cell fate determination	GO:0001709	91	0.209
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.209
regulation of growth	GO:0040008	233	0.206
regulation of intracellular signal transduction	GO:1902531	236	0.205
cell division	GO:0051301	248	0.205
phenol containing compound metabolic process	GO:0018958	57	0.202
negative regulation of organelle organization	GO:0010639	56	0.200
small gtpase mediated signal transduction	GO:0007264	88	0.199
membrane fusion	GO:0061025	42	0.198
positive regulation of molecular function	GO:0044093	136	0.198
microtubule based movement	GO:0007018	51	0.196
regulation of cell adhesion	GO:0030155	27	0.194
vesicle localization	GO:0051648	55	0.194
muscle structure development	GO:0061061	224	0.191
morphogenesis of an epithelium	GO:0002009	276	0.189	Worm
camera type eye development	GO:0043010	4	0.188
glycosyl compound metabolic process	GO:1901657	127	0.186
autophagy	GO:0006914	108	0.184
regulation of microtubule cytoskeleton organization	GO:0070507	41	0.184
regulation of mapk cascade	GO:0043408	92	0.183
response to abiotic stimulus	GO:0009628	341	0.181
cell death	GO:0008219	279	0.180
epithelium migration	GO:0090132	148	0.179	Worm
positive regulation of cellular protein metabolic process	GO:0032270	118	0.179
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.179
ribonucleoside catabolic process	GO:0042454	112	0.178
imaginal disc derived appendage development	GO:0048737	399	0.169
intracellular transport	GO:0046907	228	0.169
carbohydrate derivative catabolic process	GO:1901136	118	0.167
protein phosphorylation	GO:0006468	169	0.167
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.164
purine containing compound metabolic process	GO:0072521	155	0.163
negative regulation of protein depolymerization	GO:1901880	23	0.162
nucleobase containing small molecule metabolic process	GO:0055086	174	0.157
plasma membrane organization	GO:0007009	26	0.156	Human
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.155
taxis	GO:0042330	304	0.155	Zebrafish
regulation of protein depolymerization	GO:1901879	27	0.154
purine nucleoside metabolic process	GO:0042278	127	0.153
sensory organ morphogenesis	GO:0090596	260	0.148
nucleotide metabolic process	GO:0009117	161	0.147
regulation of programmed cell death	GO:0043067	152	0.146
cellularization	GO:0007349	90	0.145
larval development	GO:0002164	104	0.145	Worm
signal transduction by phosphorylation	GO:0023014	107	0.142
lipid metabolic process	GO:0006629	121	0.141
muscle organ development	GO:0007517	127	0.140
gland development	GO:0048732	191	0.139
positive regulation of phosphate metabolic process	GO:0045937	139	0.138
filopodium assembly	GO:0046847	33	0.138
establishment of vesicle localization	GO:0051650	51	0.137
positive regulation of catalytic activity	GO:0043085	118	0.133
nucleoside triphosphate catabolic process	GO:0009143	108	0.133
response to starvation	GO:0042594	97	0.133
photoreceptor cell development	GO:0042461	96	0.133
neural precursor cell proliferation	GO:0061351	75	0.127
protein localization	GO:0008104	284	0.123
carbohydrate derivative metabolic process	GO:1901135	217	0.123
cellular protein complex assembly	GO:0043623	71	0.122
regulation of protein phosphorylation	GO:0001932	64	0.122
regulation of organelle organization	GO:0033043	196	0.120
regulation of cellular component size	GO:0032535	98	0.120
organophosphate catabolic process	GO:0046434	112	0.119
chaeta development	GO:0022416	97	0.119
germarium derived egg chamber formation	GO:0007293	101	0.119
regulation of dendrite morphogenesis	GO:0048814	28	0.118
regulation of phosphate metabolic process	GO:0019220	210	0.118
rho protein signal transduction	GO:0007266	14	0.118
apoptotic process	GO:0006915	159	0.117
nucleotide catabolic process	GO:0009166	109	0.116
positive regulation of protein phosphorylation	GO:0001934	34	0.116
heterocycle catabolic process	GO:0046700	166	0.114
actin nucleation	GO:0045010	8	0.114
regulation of cell cycle	GO:0051726	291	0.114
organic cyclic compound catabolic process	GO:1901361	168	0.113
ribose phosphate metabolic process	GO:0019693	145	0.113
cellular lipid metabolic process	GO:0044255	83	0.111
cellular protein complex disassembly	GO:0043624	35	0.111
positive regulation of phosphorus metabolic process	GO:0010562	139	0.110
developmental cell growth	GO:0048588	52	0.109
cell projection assembly	GO:0030031	94	0.109
programmed cell death	GO:0012501	257	0.108
chromosome segregation	GO:0007059	157	0.108
cellular response to extracellular stimulus	GO:0031668	64	0.106
guanosine containing compound catabolic process	GO:1901069	74	0.106
positive regulation of dendrite morphogenesis	GO:0050775	9	0.105
nucleobase containing compound catabolic process	GO:0034655	165	0.105
intracellular signal transduction	GO:0035556	300	0.104
regulation of protein polymerization	GO:0032271	28	0.104
establishment of proximal distal cell polarity	GO:0022606	4	0.103
regulation of cell death	GO:0010941	173	0.103
positive regulation of protein metabolic process	GO:0051247	128	0.103
regulation of secretion by cell	GO:1903530	39	0.101
branching involved in open tracheal system development	GO:0060446	45	0.101
regulation of developmental growth	GO:0048638	174	0.098
leg disc morphogenesis	GO:0007478	80	0.098
cellular component disassembly	GO:0022411	46	0.097
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.096
ribonucleotide catabolic process	GO:0009261	109	0.095
response to oxygen containing compound	GO:1901700	200	0.094
neurological system process	GO:0050877	358	0.091
nucleoside phosphate metabolic process	GO:0006753	162	0.091
protein polymerization	GO:0051258	42	0.089
neuron maturation	GO:0042551	31	0.089
catabolic process	GO:0009056	409	0.089
negative regulation of multicellular organismal process	GO:0051241	142	0.087
regulation of cellular amine metabolic process	GO:0033238	3	0.087
atp metabolic process	GO:0046034	49	0.087
single organism catabolic process	GO:0044712	228	0.083
developmental growth involved in morphogenesis	GO:0060560	65	0.083
synaptic vesicle localization	GO:0097479	53	0.082
purine ribonucleotide metabolic process	GO:0009150	145	0.082
cellular response to chemical stimulus	GO:0070887	199	0.081	Zebrafish
cellular response to nutrient levels	GO:0031669	62	0.081
regulation of protein complex assembly	GO:0043254	42	0.080
microtubule based transport	GO:0010970	42	0.078
carboxylic acid metabolic process	GO:0019752	92	0.078
positive regulation of macromolecule metabolic process	GO:0010604	405	0.077
positive regulation of protein kinase activity	GO:0045860	25	0.076
microtubule depolymerization	GO:0007019	25	0.076
cell growth	GO:0016049	108	0.075
rhabdomere development	GO:0042052	38	0.075
morphogenesis of a branching structure	GO:0001763	45	0.073
regulation of molecular function	GO:0065009	217	0.073
aromatic compound catabolic process	GO:0019439	166	0.072
cortical actin cytoskeleton organization	GO:0030866	24	0.072
asymmetric cell division	GO:0008356	37	0.071
negative regulation of protein complex disassembly	GO:0043242	23	0.071
mapk cascade	GO:0000165	107	0.071
positive regulation of signaling	GO:0023056	243	0.069
sperm individualization	GO:0007291	48	0.069
learning	GO:0007612	75	0.067
regulation of cell cycle process	GO:0010564	181	0.067
post embryonic appendage morphogenesis	GO:0035120	385	0.067
developmental maturation	GO:0021700	172	0.067
cell adhesion	GO:0007155	136	0.066
negative regulation of phosphate metabolic process	GO:0045936	45	0.066
positive regulation of transferase activity	GO:0051347	26	0.065
establishment of mitochondrion localization	GO:0051654	7	0.065
defense response	GO:0006952	300	0.065
cell substrate adhesion	GO:0031589	10	0.064
cell junction assembly	GO:0034329	42	0.064
regulation of axonogenesis	GO:0050770	32	0.064
aging	GO:0007568	143	0.064
chorion containing eggshell formation	GO:0007304	105	0.064
negative regulation of developmental growth	GO:0048640	64	0.062
regulation of endocytosis	GO:0030100	37	0.062
organic substance catabolic process	GO:1901575	308	0.062
immune system process	GO:0002376	347	0.062	Human Zebrafish Mouse
regulation of cellular catabolic process	GO:0031329	157	0.061
neurotransmitter transport	GO:0006836	37	0.060
regulation of apoptotic process	GO:0042981	130	0.060
regulation of protein complex disassembly	GO:0043244	29	0.060
cellular response to growth factor stimulus	GO:0071363	30	0.060
neuron remodeling	GO:0016322	29	0.059
protein modification process	GO:0036211	438	0.058
neuromuscular synaptic transmission	GO:0007274	67	0.058
single organismal cell cell adhesion	GO:0016337	45	0.058
regulation of catabolic process	GO:0009894	170	0.057
establishment of protein localization to plasma membrane	GO:0090002	9	0.057
homeostatic process	GO:0042592	199	0.057
negative regulation of nervous system development	GO:0051961	92	0.057
positive regulation of nucleotide metabolic process	GO:0045981	55	0.055
tissue migration	GO:0090130	155	0.055	Worm
endosomal transport	GO:0016197	44	0.055	Mouse
germ line stem cell maintenance	GO:0030718	50	0.054
regulation of protein modification process	GO:0031399	112	0.054
purine ribonucleoside monophosphate metabolic process	GO:0009167	50	0.053
amine metabolic process	GO:0009308	12	0.053
spindle organization	GO:0007051	253	0.053
positive regulation of cytoskeleton organization	GO:0051495	21	0.052
regionalization	GO:0003002	416	0.052
purine nucleotide metabolic process	GO:0006163	146	0.052
embryonic organ development	GO:0048568	50	0.051
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.051
endodermal cell differentiation	GO:0035987	3	0.051
cilium morphogenesis	GO:0060271	39	0.050
determination of left right symmetry	GO:0007368	9	0.050
cellular macromolecular complex assembly	GO:0034622	153	0.050
cell junction organization	GO:0034330	57	0.050
secretion by cell	GO:0032940	101	0.050
positive regulation of multicellular organismal process	GO:0051240	143	0.050
positive regulation of hydrolase activity	GO:0051345	78	0.049
ovarian follicle cell migration	GO:0007297	121	0.049
establishment or maintenance of cell polarity	GO:0007163	167	0.049
autophagic vacuole assembly	GO:0000045	2	0.049
peptidyl tyrosine phosphorylation	GO:0018108	24	0.049
negative regulation of cellular metabolic process	GO:0031324	382	0.049
organic hydroxy compound metabolic process	GO:1901615	83	0.048
regulation of pathway restricted smad protein phosphorylation	GO:0060393	1	0.048
stress activated mapk cascade	GO:0051403	52	0.048
inter male aggressive behavior	GO:0002121	60	0.048
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.048
secretion	GO:0046903	109	0.047
cellular macromolecule localization	GO:0070727	220	0.047
mushroom body development	GO:0016319	70	0.047
positive regulation of kinase activity	GO:0033674	25	0.047
regulation of organ morphogenesis	GO:2000027	78	0.047
cognition	GO:0050890	141	0.047
positive regulation of protein polymerization	GO:0032273	14	0.046
positive regulation of protein modification process	GO:0031401	58	0.046
positive regulation of developmental growth	GO:0048639	62	0.046
cellular component assembly involved in morphogenesis	GO:0010927	151	0.046
regulation of response to stress	GO:0080134	200	0.045
positive regulation of catabolic process	GO:0009896	105	0.045
purine ribonucleoside monophosphate catabolic process	GO:0009169	38	0.044
brain development	GO:0007420	120	0.044
oocyte microtubule cytoskeleton organization	GO:0016325	35	0.044
vesicle organization	GO:0016050	44	0.044
head development	GO:0060322	135	0.044
tube morphogenesis	GO:0035239	191	0.044
negative regulation of cell proliferation	GO:0008285	69	0.043
neuron projection extension	GO:1990138	32	0.043
positive regulation of intracellular signal transduction	GO:1902533	116	0.043
cellular protein modification process	GO:0006464	438	0.042
cellular amino acid metabolic process	GO:0006520	61	0.041
single organism behavior	GO:0044708	391	0.041
positive regulation of axon guidance	GO:1902669	1	0.041
cytoskeleton dependent intracellular transport	GO:0030705	44	0.041
negative regulation of actin filament polymerization	GO:0030837	7	0.040
axon extension	GO:0048675	32	0.040
regulation of transferase activity	GO:0051338	58	0.040
single organism cell adhesion	GO:0098602	47	0.039
regulation of notch signaling pathway	GO:0008593	100	0.039
adult behavior	GO:0030534	137	0.039
regulation of transport	GO:0051049	181	0.039
r7 cell differentiation	GO:0045466	43	0.039
establishment or maintenance of microtubule cytoskeleton polarity	GO:0030951	41	0.038
cellular response to organic substance	GO:0071310	132	0.038
stem cell development	GO:0048864	79	0.038
positive regulation of filopodium assembly	GO:0051491	15	0.038
neuronal stem cell division	GO:0036445	35	0.037
regulation of microtubule based process	GO:0032886	49	0.037
epithelial cell migration	GO:0010631	148	0.037	Worm
somatic stem cell division	GO:0048103	37	0.036
cellular response to starvation	GO:0009267	61	0.036
neurotransmitter secretion	GO:0007269	35	0.036
neuron projection guidance	GO:0097485	241	0.036
regulation of protein serine threonine kinase activity	GO:0071900	25	0.036
negative regulation of microtubule polymerization or depolymerization	GO:0031111	21	0.036
cellular nitrogen compound catabolic process	GO:0044270	165	0.036
regulation of hydrolase activity	GO:0051336	97	0.035
digestive tract morphogenesis	GO:0048546	127	0.035
lamellipodium organization	GO:0097581	21	0.034
segmentation	GO:0035282	207	0.034
purine nucleoside monophosphate catabolic process	GO:0009128	38	0.034
stem cell division	GO:0017145	69	0.034
cellular protein localization	GO:0034613	160	0.033
positive regulation of endocytosis	GO:0045807	22	0.033
positive regulation of peptidase activity	GO:0010952	29	0.033
imaginal disc derived wing hair site selection	GO:0035320	4	0.033
positive regulation of purine nucleotide catabolic process	GO:0033123	46	0.032
mesoderm development	GO:0007498	78	0.032
g protein coupled receptor signaling pathway	GO:0007186	136	0.032
positive regulation of endopeptidase activity	GO:0010950	26	0.032
response to inorganic substance	GO:0010035	44	0.032
regulation of synapse structural plasticity	GO:0051823	3	0.032
myoblast proliferation	GO:0051450	3	0.031
signal release	GO:0023061	49	0.031
positive regulation of transport	GO:0051050	92	0.030
negative regulation of autophagy	GO:0010507	16	0.030
muscle cell fate commitment	GO:0042693	14	0.030
morphogenesis of embryonic epithelium	GO:0016331	94	0.030	Worm
determination of bilateral symmetry	GO:0009855	13	0.030
response to organonitrogen compound	GO:0010243	75	0.030
response to radiation	GO:0009314	155	0.030
positive regulation of gtpase activity	GO:0043547	43	0.029
gland morphogenesis	GO:0022612	145	0.029
regulation of cellular amino acid metabolic process	GO:0006521	0	0.029
retina development in camera type eye	GO:0060041	4	0.029
eggshell formation	GO:0030703	105	0.029
establishment or maintenance of cytoskeleton polarity	GO:0030952	44	0.029
regulation of neuroblast proliferation	GO:1902692	34	0.029
phagocytosis	GO:0006909	215	0.028
negative regulation of cell development	GO:0010721	62	0.028
epidermal cell differentiation	GO:0009913	51	0.028
membrane tubulation	GO:0097320	4	0.028	Human
regulation of neuron death	GO:1901214	26	0.028
hindbrain development	GO:0030902	2	0.027
regulation of microtubule polymerization or depolymerization	GO:0031110	27	0.027
positive regulation of cellular amine metabolic process	GO:0033240	0	0.027
open tracheal system development	GO:0007424	204	0.027
multicellular organismal aging	GO:0010259	140	0.027
positive regulation of cell projection organization	GO:0031346	29	0.027
body morphogenesis	GO:0010171	2	0.027
cell type specific apoptotic process	GO:0097285	38	0.027
regulation of kinase activity	GO:0043549	53	0.027
endoderm formation	GO:0001706	3	0.027
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.027
stem cell proliferation	GO:0072089	88	0.027
respiratory system development	GO:0060541	213	0.026
positive regulation of phosphorylation	GO:0042327	87	0.026
protein depolymerization	GO:0051261	31	0.026
organic substance transport	GO:0071702	257	0.026
digestive system development	GO:0055123	149	0.026
neuroblast division	GO:0055057	35	0.026
peptidyl threonine phosphorylation	GO:0018107	2	0.026
neuron fate determination	GO:0048664	1	0.026
peptidyl amino acid modification	GO:0018193	105	0.026
positive regulation of gtp catabolic process	GO:0033126	43	0.026
determination of adult lifespan	GO:0008340	137	0.025
positive regulation of axon extension	GO:0045773	2	0.025
histolysis	GO:0007559	102	0.025
mitochondrion localization	GO:0051646	17	0.025
muscle attachment	GO:0016203	36	0.025
lipid storage	GO:0019915	38	0.025
protein localization to plasma membrane	GO:0072659	13	0.024
regulation of autophagy	GO:0010506	62	0.024
spindle localization	GO:0051653	22	0.024	Mouse
telencephalon development	GO:0021537	2	0.024
positive regulation of cell death	GO:0010942	69	0.024
response to nutrient levels	GO:0031667	114	0.024
dorsal appendage formation	GO:0046843	47	0.024
axon guidance	GO:0007411	233	0.024
nucleoside monophosphate catabolic process	GO:0009125	39	0.024
anterograde synaptic vesicle transport	GO:0048490	3	0.024
negative regulation of response to stimulus	GO:0048585	258	0.023
cortical cytoskeleton organization	GO:0030865	29	0.023
regulation of nucleoside metabolic process	GO:0009118	50	0.023
transcription from rna polymerase ii promoter	GO:0006366	368	0.023
positive regulation of nucleoside metabolic process	GO:0045979	47	0.023
microtubule bundle formation	GO:0001578	27	0.023
positive regulation of biosynthetic process	GO:0009891	316	0.023
asymmetric protein localization	GO:0008105	33	0.023
anterograde axon cargo transport	GO:0008089	6	0.022
regulation of purine nucleotide catabolic process	GO:0033121	48	0.022
cellular response to external stimulus	GO:0071496	66	0.022
germ line stem cell division	GO:0042078	25	0.022
protein localization to membrane	GO:0072657	19	0.022
mitochondrion organization	GO:0007005	65	0.022
cell competition in a multicellular organism	GO:0035212	10	0.022
axon extension involved in axon guidance	GO:0048846	10	0.022
positive regulation of ras gtpase activity	GO:0032320	36	0.022
positive regulation of cell differentiation	GO:0045597	64	0.022
morphogenesis of a branching epithelium	GO:0061138	45	0.021
regulation of stress activated mapk cascade	GO:0032872	41	0.021
positive regulation of jun kinase activity	GO:0043507	4	0.021
embryonic axis specification	GO:0000578	107	0.021
negative regulation of neurogenesis	GO:0050768	53	0.021
dorsal closure elongation of leading edge cells	GO:0007394	10	0.021

WASp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.067	Human
	cardiovascular system disease	DOID:1287	0	0.062

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