Drosophila melanogaster

79 known processes

Dr (Dmel_CG1897)

Drop

(Aliases: msh,Msx,msh1,l(3)FA30,Msh,153515_at,ltt,Dmel\CG1897,CG1897,99B,msh-1)

Dr biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
imaginal disc derived appendage developmentGO:00487373990.144
wing disc morphogenesisGO:00074723440.122
regulation of intracellular signal transductionGO:19025312360.122
Human
negative regulation of cellular metabolic processGO:00313243820.120
Mouse
appendage developmentGO:00487364010.115
intracellular signal transductionGO:00355563000.111
Human
cellular protein modification processGO:00064644380.107
Mouse
multi organism behaviorGO:00517051750.106
negative regulation of gene expressionGO:00106293870.098
imaginal disc derived appendage morphogenesisGO:00351143950.093
cell proliferationGO:00082832990.091
Mouse
regionalizationGO:00030024160.091
positive regulation of signalingGO:00230562430.087
Human Mouse
phosphorylationGO:00163102940.081
response to organic substanceGO:00100332840.080
Mouse Rat
positive regulation of response to stimulusGO:00485843230.075
Human Mouse
establishment of localization in cellGO:00516494020.074
taxisGO:00423303040.073
negative regulation of cellular biosynthetic processGO:00313272770.068
Mouse
post embryonic appendage morphogenesisGO:00351203850.068
positive regulation of rna biosynthetic processGO:19026802660.063
Mouse
forebrain developmentGO:003090020.063
Mouse Rat
response to oxygen containing compoundGO:19017002000.059
Mouse
positive regulation of nucleobase containing compound metabolic processGO:00459353320.059
Mouse
positive regulation of nucleic acid templated transcriptionGO:19035082660.058
Mouse
response to endogenous stimulusGO:00097191190.057
Mouse Rat
regulation of multicellular organismal developmentGO:20000264140.057
Mouse
neurological system processGO:00508773580.057
multi organism reproductive behaviorGO:00447051210.056
neuron projection guidanceGO:00974852410.053
positive regulation of macromolecule metabolic processGO:00106044050.052
Mouse
regulation of cellular protein metabolic processGO:00322682430.052
Mouse
positive regulation of gene expressionGO:00106282900.051
Mouse
cell motilityGO:00488702510.050
Mouse
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.050
Mouse
regulation of transcription from rna polymerase ii promoterGO:00063573780.050
Mouse Rat
cellular response to chemical stimulusGO:00708871990.050
Mouse Rat
regulation of cell developmentGO:00602842150.049
connective tissue developmentGO:006144830.049
Mouse Rat
regulation of anatomical structure morphogenesisGO:00226032420.048
Mouse
regulation of cellular ketone metabolic processGO:001056530.048
deathGO:00162652840.047
Human Zebrafish Mouse Rat Worm
transcription from rna polymerase ii promoterGO:00063663680.047
Mouse Rat
enzyme linked receptor protein signaling pathwayGO:00071671790.046
Mouse
regulation of cell proliferationGO:00421271630.046
Mouse
response to organic cyclic compoundGO:0014070890.046
Mouse Rat
negative regulation of response to stimulusGO:00485852580.045
dorsal ventral pattern formationGO:00099531330.045
negative regulation of cell communicationGO:00106482230.045
axon developmentGO:00615642970.044
regulation of localizationGO:00328792750.044
cellular amine metabolic processGO:0044106120.044
vesicle mediated transportGO:00161923810.043
brain developmentGO:00074201200.043
organonitrogen compound metabolic processGO:19015643180.043
catabolic processGO:00090564090.042
cellular amino acid metabolic processGO:0006520610.042
endocytosisGO:00068973100.042
negative regulation of nucleic acid templated transcriptionGO:19035072400.042
Mouse
epithelial cell developmentGO:00020642740.042
appendage morphogenesisGO:00351073970.041
regulation of protein metabolic processGO:00512462560.041
Mouse
male mating behaviorGO:0060179700.040
positive regulation of cell communicationGO:00106472500.040
Human Mouse
organonitrogen compound biosynthetic processGO:19015661170.040
epithelial cell differentiationGO:00308553220.039
Mouse
imaginal disc derived wing morphogenesisGO:00074763370.038
positive regulation of signal transductionGO:00099672230.038
Human Mouse
organic substance transportGO:00717022570.038
axon guidanceGO:00074112330.037
compound eye morphogenesisGO:00017452490.037
amine metabolic processGO:0009308120.037
sensory perceptionGO:00076001960.037
carboxylic acid metabolic processGO:0019752920.036
chromosome organizationGO:00512763600.035
Mouse
regulation of immune responseGO:00507761180.035
response to organonitrogen compoundGO:0010243750.035
Rat
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.035
Mouse
regulation of phosphorylationGO:00423251470.035
positive regulation of intracellular signal transductionGO:19025331160.035
Human
negative regulation of signalingGO:00230572190.035
chemotaxisGO:00069352490.035
positive regulation of multicellular organismal processGO:00512401430.035
Mouse
positive regulation of phosphorylationGO:0042327870.034
negative regulation of rna biosynthetic processGO:19026792400.034
Mouse
reproductive behaviorGO:00190981220.034
immune response regulating signaling pathwayGO:000276420.034
positive regulation of developmental processGO:00510941430.033
Mouse
positive regulation of rna metabolic processGO:00512542710.033
Mouse
single organism biosynthetic processGO:00447112060.033
growthGO:00400073590.033
Human Zebrafish Mouse
programmed cell deathGO:00125012570.033
Human Zebrafish Mouse Rat Worm
positive regulation of cell migrationGO:003033520.032
camera type eye developmentGO:004301040.032
positive regulation of cellular biosynthetic processGO:00313283160.032
Mouse
regulation of cell cycleGO:00517262910.032
Mouse
matingGO:00076181200.031
ameboidal type cell migrationGO:00016671510.031
positive regulation of cell motilityGO:200014730.031
defense responseGO:00069523000.031
response to other organismGO:00517072930.031
single organism behaviorGO:00447083910.030
immune responseGO:00069552460.030
regulation of cell differentiationGO:00455953020.030
regulation of nervous system developmentGO:00519602480.030
developmental growthGO:00485892800.030
Zebrafish Mouse
organic substance catabolic processGO:19015753080.030
protein modification processGO:00362114380.030
Mouse
tube developmentGO:00352952440.030
Mouse
regulation of programmed cell deathGO:00430671520.030
Human Zebrafish Mouse Rat
axonogenesisGO:00074092900.029
digestive system developmentGO:00551231490.029
telencephalon developmentGO:002153720.029
positive regulation of nitrogen compound metabolic processGO:00511733540.029
Mouse
photoreceptor cell differentiationGO:00465301700.029
response to bacteriumGO:00096171980.029
eye morphogenesisGO:00485922600.029
negative regulation of biosynthetic processGO:00098902770.029
Mouse
learning or memoryGO:00076111410.028
response to external biotic stimulusGO:00432072930.028
organic acid metabolic processGO:00060821030.028
lipid metabolic processGO:00066291210.028
positive regulation of biosynthetic processGO:00098913160.028
Mouse
cell migrationGO:00164772380.028
Mouse
neuron recognitionGO:00080381010.027
secretionGO:00469031090.027
cellular catabolic processGO:00442483720.027
negative regulation of signal transductionGO:00099682060.027
embryonic development via the syncytial blastodermGO:00017001480.027
hindbrain developmentGO:003090220.027
cell divisionGO:00513012480.026
Mouse
biological adhesionGO:00226101380.026
tube morphogenesisGO:00352391910.026
Mouse
positive regulation of nervous system developmentGO:0051962690.026
peripheral nervous system developmentGO:0007422520.026
regulation of mapk cascadeGO:0043408920.026
small molecule metabolic processGO:00442813050.026
regulation of neuron differentiationGO:00456641030.026
chaeta developmentGO:0022416970.026
kidney developmentGO:000182230.025
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.025
Mouse
rna splicingGO:0008380830.025
negative regulation of developmental processGO:00510932010.025
Mouse
immune response activating signal transductionGO:000275720.025
negative regulation of macromolecule biosynthetic processGO:00105582700.025
Mouse
response to lipopolysaccharideGO:003249640.025
cell cell signaling involved in cell fate commitmentGO:00451682100.025
positive regulation of cellular component organizationGO:00511301560.025
Mouse
sensory perception of soundGO:0007605560.025
central nervous system developmentGO:00074172010.024
morphogenesis of an epitheliumGO:00020092760.024
Zebrafish Mouse
negative regulation of nucleobase containing compound metabolic processGO:00459342610.024
Mouse
cellular response to endogenous stimulusGO:0071495800.024
Mouse Rat
positive regulation of cellular protein metabolic processGO:00322701180.024
response to nitrogen compoundGO:1901698900.024
Rat
positive regulation of phosphorus metabolic processGO:00105621390.024
response to abiotic stimulusGO:00096283410.024
posttranscriptional regulation of gene expressionGO:00106081450.024
Human
positive regulation of molecular functionGO:00440931360.023
regulation of organelle organizationGO:00330431960.023
Mouse
tissue morphogenesisGO:00487292970.023
Zebrafish Mouse
organelle fissionGO:00482853400.023
Mouse
regulation of organ morphogenesisGO:2000027780.023
Mouse
small gtpase mediated signal transductionGO:0007264880.023
positive regulation of transcription dna templatedGO:00458932660.023
Mouse
body morphogenesisGO:001017120.023
Human Mouse
courtship behaviorGO:0007619680.023
locomotory behaviorGO:00076261760.023
Worm
negative regulation of nitrogen compound metabolic processGO:00511722650.023
Mouse
extrinsic apoptotic signaling pathwayGO:009719110.023
secretion by cellGO:00329401010.023
positive regulation of macromolecule biosynthetic processGO:00105572830.023
Mouse
muscle structure developmentGO:00610612240.023
Mouse
positive regulation of protein metabolic processGO:00512471280.023
regulation of response to stressGO:00801342000.023
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.022
Mouse
regulation of response to external stimulusGO:00321011150.022
homeostatic processGO:00425921990.022
localization of cellGO:00516742570.022
Mouse
sensory organ morphogenesisGO:00905962600.022
Zebrafish Mouse
adult behaviorGO:00305341370.022
embryo development ending in birth or egg hatchingGO:00097921520.022
Zebrafish Mouse
compound eye developmentGO:00487493070.022
regulation of developmental growthGO:00486381740.022
cognitionGO:00508901410.022
regulation of multi organism processGO:00439001310.022
digestive tract developmentGO:00485651490.022
nephron morphogenesisGO:007202830.022
segmentationGO:00352822070.022
ras protein signal transductionGO:0007265880.022
regulation of phosphorus metabolic processGO:00511742100.022
regulation of immune system processGO:00026821760.022
defense response to other organismGO:00985422250.021
response to biotic stimulusGO:00096072940.021
cell deathGO:00082192790.021
Human Zebrafish Mouse Rat Worm
regulation of immune effector processGO:0002697520.021
phagocytosisGO:00069092150.021
positive regulation of immune system processGO:0002684680.021
multicellular organismal reproductive behaviorGO:00330571100.021
regulation of mitotic cell cycleGO:00073461900.021
immune effector processGO:0002252980.021
negative regulation of transcription dna templatedGO:00458922370.021
Mouse
compound eye photoreceptor cell differentiationGO:00017511400.021
oxoacid metabolic processGO:00434361030.020
regulation of transportGO:00510491810.020
tissue migrationGO:00901301550.020
response to ethanolGO:0045471590.020
immune system processGO:00023763470.020
protein phosphorylationGO:00064681690.020
cytoplasmic transportGO:00164821300.020
signal transduction by phosphorylationGO:00230141070.020
embryonic pattern specificationGO:00098801740.020
polyol biosynthetic processGO:004617330.020
mesoderm developmentGO:0007498780.019
negative regulation of programmed cell deathGO:0043069720.019
Mouse
protein localizationGO:00081042840.019
Human
regulation of cell projection organizationGO:0031344920.019
columnar cuboidal epithelial cell differentiationGO:00020652560.019
regulation of neurogenesisGO:00507671580.019
negative regulation of rna metabolic processGO:00512532510.019
Mouse
blastoderm segmentationGO:00073501590.019
synaptic transmissionGO:00072682880.019
cellular ketone metabolic processGO:0042180240.019
regulation of proteolysisGO:0030162870.019
proteolysisGO:00065081920.019
gland developmentGO:00487321910.019
Mouse Rat
male gamete generationGO:00482322010.019
ion transportGO:00068111450.018
respiratory system developmentGO:00605412130.018
kidney epithelium developmentGO:007207330.018
positive regulation of phosphate metabolic processGO:00459371390.018
positive regulation of immune responseGO:0050778630.018
multi multicellular organism processGO:00447061230.018
Worm
ovarian follicle cell developmentGO:00307072480.018
mrna splicing via spliceosomeGO:0000398730.018
response to monosaccharideGO:003428440.018
single organism catabolic processGO:00447122280.018
regulation of phosphate metabolic processGO:00192202100.018
carbohydrate derivative metabolic processGO:19011352170.018
stem cell differentiationGO:00488631170.018
Mouse
nitrogen compound transportGO:0071705850.017
cell adhesionGO:00071551360.017
cation transportGO:00068121100.017
cellular macromolecule localizationGO:00707272200.017
Human
intracellular transportGO:00469072280.017
ion transmembrane transportGO:00342201220.017
neuroblast proliferationGO:0007405740.017
memoryGO:0007613940.017
mating behaviorGO:00076171060.017
response to organophosphorusGO:004668320.017
regulation of chromosome organizationGO:0033044640.017
Mouse
regulation of apoptotic processGO:00429811300.017
Human Zebrafish Mouse Rat
regulation of locomotionGO:0040012420.017
negative regulation of cell differentiationGO:00455961430.016
Mouse
columnar cuboidal epithelial cell developmentGO:00020662490.016
chromosome segregationGO:00070591570.016
neural precursor cell proliferationGO:0061351750.016
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.016
Mouse
regulation of epithelial cell differentiationGO:003085640.016
Mouse
monocarboxylic acid transportGO:001571830.016
stem cell maintenanceGO:0019827670.016
regulation of defense responseGO:00313471020.016
response to temperature stimulusGO:00092661060.016
motor neuron axon guidanceGO:0008045580.016
regulation of response to biotic stimulusGO:0002831630.016
innate immune responseGO:00450871440.016
regulation of epithelial cell proliferationGO:005067840.016
positive regulation of cellular amine metabolic processGO:003324000.016
spermatogenesisGO:00072832000.016
response to alcoholGO:0097305950.016
Mouse
head developmentGO:00603221350.016
imaginal disc derived wing vein morphogenesisGO:0008586440.016
lipid localizationGO:0010876540.016
spinal cord developmentGO:002151010.016
acetylcholine catabolic processGO:000658110.016
negative regulation of cell cycleGO:00457861160.016
regulation of protein modification processGO:00313991120.016
Mouse
anatomical structure homeostasisGO:0060249970.016
response to hexoseGO:000974630.016
mapk cascadeGO:00001651070.015
nephron epithelium developmentGO:007200930.015
cellular lipid metabolic processGO:0044255830.015
defense response to bacteriumGO:00427421780.015
leg disc developmentGO:0035218920.015
amide biosynthetic processGO:0043604420.015
response to growth factorGO:0070848310.015
Mouse
defense response to gram negative bacteriumGO:0050829940.015
carbohydrate derivative biosynthetic processGO:1901137850.015
regulation of synapse structure and activityGO:00508031280.015
regulation of molecular functionGO:00650092170.015
Mouse
axis specificationGO:00097981670.015
salivary gland morphogenesisGO:00074351450.015
imaginal disc derived leg morphogenesisGO:0007480800.015
cellular macromolecule catabolic processGO:00442651360.015
dendrite morphogenesisGO:00488131990.015
regulation of gene expression epigeneticGO:00400291280.015
organic hydroxy compound biosynthetic processGO:1901617210.015
positive regulation of cell proliferationGO:0008284470.015
nephron developmentGO:007200630.015
single organism intracellular transportGO:19025822070.015
eye antennal disc developmentGO:0035214600.015
histone modificationGO:00165701060.015
Mouse
spermatid differentiationGO:00485151140.015
regulation of cellular amine metabolic processGO:003323830.015
mesenchymal cell developmentGO:001403110.015
Mouse
hematopoietic progenitor cell differentiationGO:000224410.015
cell fate specificationGO:0001708710.014
rna processingGO:00063961470.014
mesenchymal cell differentiationGO:004876210.014
Mouse
regulation of cellular amino acid metabolic processGO:000652100.014
gland morphogenesisGO:00226121450.014
Mouse
regulation of embryonic developmentGO:0045995680.014
gastrulationGO:0007369700.014
regulation of small gtpase mediated signal transductionGO:0051056930.014
stem cell proliferationGO:0072089880.014
Mouse
camera type eye morphogenesisGO:004859320.014
positive regulation of mapk cascadeGO:0043410630.014
regulation of cellular localizationGO:00603411360.014
stem cell developmentGO:0048864790.014
Mouse
eye developmentGO:00016543230.014
jak stat cascadeGO:0007259490.014
regulation of mrna processingGO:0050684710.014
negative regulation of nervous system developmentGO:0051961920.014
limb morphogenesisGO:003510810.014
Human Mouse
digestive tract morphogenesisGO:00485461270.014
maintenance of locationGO:0051235730.014
positive regulation of cellular amino acid metabolic processGO:004576400.014
notch signaling pathwayGO:00072191200.014
negative regulation of cell deathGO:0060548810.014
Mouse
negative regulation of intracellular signal transductionGO:1902532570.014
steroid catabolic processGO:000670610.013
pigment metabolic processGO:0042440840.013
eye photoreceptor cell differentiationGO:00017541450.013
response to extracellular stimulusGO:00099911160.013
mrna processingGO:00063971040.013
positive regulation of programmed cell deathGO:0043068620.013
Human Mouse Rat
cholesterol homeostasisGO:004263230.013
response to glucoseGO:000974920.013
sensory perception of smellGO:0007608800.013
synapse organizationGO:00508081960.013
positive regulation of organelle organizationGO:0010638650.013
Mouse
purine ribonucleotide metabolic processGO:00091501450.013
lateral inhibitionGO:00463312060.013
negative regulation of apoptotic processGO:0043066630.013
Mouse
response to hormoneGO:0009725450.013
Mouse
modification dependent macromolecule catabolic processGO:0043632790.013
larval lymph gland hemopoiesisGO:0035167170.013
actin filament organizationGO:00070151260.013
nephron tubule morphogenesisGO:007207830.013
mrna metabolic processGO:00160711240.012
macromolecule catabolic processGO:00090571610.012
positive regulation of catalytic activityGO:00430851180.012
ubiquitin dependent protein catabolic processGO:0006511780.012
regulation of catalytic activityGO:00507901850.012
male courtship behaviorGO:0008049630.012
cell maturationGO:00484691440.012
embryonic morphogenesisGO:00485982060.012
Human Zebrafish Mouse Worm
dendrite developmentGO:00163582040.012
chromatin organizationGO:00063252070.012
Mouse
acid secretionGO:004671710.012
protein transportGO:00150311550.012
anterior posterior pattern specificationGO:00099521360.012
Mouse
neurotransmitter catabolic processGO:004213510.012
positive regulation of peptidyl tyrosine phosphorylationGO:005073140.012
regulation of cellular component biogenesisGO:00440872010.012
multicellular organismal agingGO:00102591400.012
purine containing compound metabolic processGO:00725211550.012
muscle organ developmentGO:00075171270.012
Mouse
autophagyGO:00069141080.012
negative regulation of cell cycle processGO:00109481090.012
organophosphate biosynthetic processGO:0090407460.012
anion transportGO:0006820410.012
myotube cell developmentGO:001490430.012
triglyceride biosynthetic processGO:001943220.012
larval developmentGO:00021641040.012
dorsal ventral axis specificationGO:0009950660.012
developmental maturationGO:00217001720.012
Mouse
cellular protein localizationGO:00346131600.012
Human
inter male aggressive behaviorGO:0002121600.012
ethanolamine containing compound metabolic processGO:004243940.012
regenerationGO:0031099160.011
Zebrafish
regulation of cell deathGO:00109411730.011
Human Zebrafish Mouse Rat
erbb signaling pathwayGO:0038127580.011
regulation of ras protein signal transductionGO:0046578930.011
establishment or maintenance of cell polarityGO:00071631670.011
smoothened signaling pathwayGO:0007224490.011
regulation of erbb signaling pathwayGO:1901184420.011
actin cytoskeleton organizationGO:00300362060.011
nephron tubule developmentGO:007208030.011
regulation of mitotic cell cycle phase transitionGO:19019901300.011
response to woundingGO:0009611940.011
Zebrafish Mouse
single organism cellular localizationGO:19025801800.011
dorsal closureGO:0007391790.011
organic anion transportGO:0015711280.011
neuron fate commitmentGO:0048663500.011
synaptic target recognitionGO:0008039450.011
regulation of mrna splicing via spliceosomeGO:0048024640.011
negative regulation of multicellular organismal processGO:00512411420.011
Mouse
carbohydrate metabolic processGO:0005975820.011
regulation of synapse organizationGO:00508071100.011
wing disc pattern formationGO:0035222660.011
formation of anatomical boundaryGO:0048859370.011
tissue homeostasisGO:0001894360.011
positive regulation of apoptotic processGO:0043065470.011
Human Mouse Rat
regulation of cell cycle processGO:00105641810.011
Mouse
open tracheal system developmentGO:00074242040.011
negative regulation of cellular component organizationGO:00511291080.011
Mouse
regulation of cellular response to stressGO:0080135890.011
regulation of cellular component movementGO:0051270420.011
mitotic cell cycle phase transitionGO:00447721380.011
wound healingGO:0042060750.011
Zebrafish Mouse
regulation of antimicrobial humoral responseGO:0002759500.011
kidney morphogenesisGO:006099330.011
peptidyl tyrosine modificationGO:0018212240.011
proximal distal pattern formationGO:0009954150.011
regulation of protein phosphorylationGO:0001932640.011
heart developmentGO:0007507820.011
Mouse
glandular epithelial cell differentiationGO:000206710.011
regulation of humoral immune responseGO:0002920510.011
rhythmic processGO:00485111060.010
salivary gland developmentGO:00074311620.010
nucleoside phosphate metabolic processGO:00067531620.010
establishment of protein localizationGO:00451841630.010
negative regulation of developmental growthGO:0048640640.010
response to acid chemicalGO:0001101250.010
regulation of innate immune responseGO:0045088710.010
regulation of hormone levelsGO:0010817400.010
mitotic nuclear divisionGO:00070672130.010
protein secretionGO:0009306450.010
cellular response to organic substanceGO:00713101320.010
Mouse Rat
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.010
negative regulation of wnt signaling pathwayGO:0030178280.010
developmental programmed cell deathGO:00106231380.010
morphogenesis of a polarized epitheliumGO:0001738930.010
acetylcholine metabolic processGO:000829120.010
chromatin modificationGO:00165681470.010
Mouse
exocrine system developmentGO:00352721620.010
positive regulation of cell developmentGO:0010720610.010
tripartite regional subdivisionGO:00073511030.010
regulation of cellular amide metabolic processGO:0034248390.010
organelle localizationGO:00516401480.010
multicellular organismal homeostasisGO:0048871410.010
positive regulation of transportGO:0051050920.010

Dr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:65500.034
disease of metabolismDOID:001466700.034
disease of anatomical entityDOID:700.032
Human
disease of cellular proliferationDOID:1456600.017
nervous system diseaseDOID:86300.015
cardiovascular system diseaseDOID:128700.015
cancerDOID:16200.015
organ system cancerDOID:005068600.011
sensory system diseaseDOID:005015500.010