Drosophila melanogaster

18 known processes

D2R (Dmel_CG33517)

Dopamine 2-like receptor

(Aliases: CG33517,anon-WO0170980.32,DD2R,CG9569,Dmel\CG33517,CG17004,anon-WO0170980.31,anon-WO0170980.130,anon-WO0170980.131,Dop2R)

D2R biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
feeding behaviorGO:0007631500.485
Mouse
detection of chemical stimulusGO:0009593930.215
single organism behaviorGO:00447083910.192
Human Mouse Rat
g protein coupled receptor signaling pathwayGO:00071861360.164
phenol containing compound metabolic processGO:0018958570.149
Mouse
detection of chemical stimulus involved in sensory perceptionGO:0050907750.124
chemosensory behaviorGO:00076351060.121
Rat
positive regulation of gene expressionGO:00106282900.120
Rat
regulation of transcription from rna polymerase ii promoterGO:00063573780.093
Rat
response to alkaloidGO:0043279260.088
Human Mouse Rat
negative regulation of nitrogen compound metabolic processGO:00511722650.082
Human Rat
organonitrogen compound metabolic processGO:19015643180.081
Human Mouse Rat
detection of stimulusGO:00516061560.074
male mating behaviorGO:0060179700.070
defense responseGO:00069523000.069
Rat
positive regulation of nucleobase containing compound metabolic processGO:00459353320.061
Rat
sensory perception of chemical stimulusGO:00076061160.061
Mouse
defense response to bacteriumGO:00427421780.061
response to insecticideGO:0017085140.058
negative regulation of cellular metabolic processGO:00313243820.057
Human Rat
negative regulation of nucleobase containing compound metabolic processGO:00459342610.057
Human Rat
positive regulation of cellular biosynthetic processGO:00313283160.056
Rat
positive regulation of rna metabolic processGO:00512542710.055
Rat
positive regulation of transcription dna templatedGO:00458932660.055
Rat
positive regulation of biosynthetic processGO:00098913160.054
Rat
response to organic substanceGO:00100332840.053
Human Mouse Rat
negative regulation of gene expressionGO:00106293870.052
Rat
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.051
Rat
response to other organismGO:00517072930.051
defense response to other organismGO:00985422250.049
columnar cuboidal epithelial cell differentiationGO:00020652560.048
pigment metabolic processGO:0042440840.048
multi organism reproductive behaviorGO:00447051210.047
positive regulation of rna biosynthetic processGO:19026802660.047
Rat
carbohydrate derivative metabolic processGO:19011352170.046
Human Rat
negative regulation of camp metabolic processGO:003081530.045
Human Rat
regulation of developmental growthGO:00486381740.045
Mouse
transcription from rna polymerase ii promoterGO:00063663680.045
Rat
response to external biotic stimulusGO:00432072930.045
regulation of cell sizeGO:0008361630.044
anatomical structure homeostasisGO:0060249970.044
response to biotic stimulusGO:00096072940.043
melanization defense responseGO:0035006450.042
response to radiationGO:00093141550.042
Mouse Rat
negative regulation of biosynthetic processGO:00098902770.041
Human Rat
nucleotide metabolic processGO:00091171610.041
Human Rat
regulation of anatomical structure morphogenesisGO:00226032420.040
positive regulation of macromolecule metabolic processGO:00106044050.039
Human Rat
epithelial cell developmentGO:00020642740.037
neurological system processGO:00508773580.037
Human Mouse Rat
innate immune responseGO:00450871440.037
regulation of behaviorGO:0050795750.036
Rat
melanin metabolic processGO:0006582470.036
immune responseGO:00069552460.036
immune system processGO:00023763470.033
response to monosaccharideGO:003428440.032
circadian rhythmGO:00076231050.032
Mouse Rat
protein modification processGO:00362114380.032
Human Rat
developmental maturationGO:00217001720.031
compound eye morphogenesisGO:00017452490.031
heart processGO:0003015370.031
Mouse
regulation of camp biosynthetic processGO:0030817120.030
Human Rat
ribonucleotide metabolic processGO:00092591450.030
Human Rat
phospholipase c activating g protein coupled receptor signaling pathwayGO:0007200100.030
Human Mouse
regulation of growthGO:00400082330.030
Mouse
sensory perceptionGO:00076001960.029
Mouse
adult behaviorGO:00305341370.029
Human Mouse Rat
sensory perception of smellGO:0007608800.029
Mouse
lateral inhibitionGO:00463312060.029
purine containing compound biosynthetic processGO:0072522300.028
Human Rat
carbohydrate derivative biosynthetic processGO:1901137850.027
Human Rat
regionalizationGO:00030024160.027
macromolecular complex assemblyGO:00650032560.027
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188170.027
Human Mouse Rat
response to light stimulusGO:00094161240.026
Mouse Rat
negative regulation of nucleic acid templated transcriptionGO:19035072400.026
Rat
cellular protein modification processGO:00064644380.026
Human Rat
adult feeding behaviorGO:0008343130.026
positive regulation of nitrogen compound metabolic processGO:00511733540.026
Rat
epithelial cell differentiationGO:00308553220.026
cell deathGO:00082192790.025
negative regulation of rna metabolic processGO:00512532510.025
Rat
growthGO:00400073590.025
Mouse
columnar cuboidal epithelial cell developmentGO:00020662490.025
response to extracellular stimulusGO:00099911160.025
detection of light stimulusGO:0009583580.025
nucleobase containing small molecule metabolic processGO:00550861740.025
Human Rat
negative regulation of rna biosynthetic processGO:19026792400.024
Rat
response to bacteriumGO:00096171980.024
purine nucleotide metabolic processGO:00061631460.024
Human Rat
post embryonic appendage morphogenesisGO:00351203850.023
purine ribonucleotide metabolic processGO:00091501450.023
Human Rat
multi organism behaviorGO:00517051750.023
positive regulation of nucleic acid templated transcriptionGO:19035082660.023
Rat
dna metabolic processGO:00062592270.023
homeostatic processGO:00425921990.023
Human Mouse Rat
oocyte differentiationGO:00099941450.023
larval behaviorGO:0030537420.023
telencephalon developmentGO:002153720.023
Mouse Rat
regulation of nervous system developmentGO:00519602480.022
Mouse
tube morphogenesisGO:00352391910.022
negative regulation of macromolecule biosynthetic processGO:00105582700.022
Rat
ribose phosphate metabolic processGO:00196931450.022
Human Rat
deathGO:00162652840.021
sensory perception of tasteGO:0050909250.021
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187170.021
Human Mouse Rat
cellular response to carbohydrate stimulusGO:007132240.021
regulation of anatomical structure sizeGO:00900661630.021
cell cell signaling involved in cell fate commitmentGO:00451682100.021
chromosome organizationGO:00512763600.021
protein complex assemblyGO:00064612000.021
compound eye developmentGO:00487493070.021
defense response to gram negative bacteriumGO:0050829940.020
positive regulation of macromolecule biosynthetic processGO:00105572830.020
Rat
regulation of nucleotide biosynthetic processGO:0030808140.020
Human Rat
forebrain developmentGO:003090020.019
Mouse Rat
regulation of protein metabolic processGO:00512462560.019
Human Rat
cellular ketone metabolic processGO:0042180240.019
response to toxic substanceGO:0009636220.019
Rat
oocyte developmentGO:00485991240.018
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.018
Rat
chromatin organizationGO:00063252070.018
positive regulation of developmental processGO:00510941430.018
Mouse
ovarian follicle cell developmentGO:00307072480.018
purine containing compound metabolic processGO:00725211550.018
Human Rat
covalent chromatin modificationGO:00165691060.018
negative regulation of signal transductionGO:00099682060.018
Human Mouse Rat
eye photoreceptor cell differentiationGO:00017541450.018
regulation of cell cycleGO:00517262910.018
Human Rat
carboxylic acid metabolic processGO:0019752920.018
organic hydroxy compound metabolic processGO:1901615830.018
Mouse
organic substance catabolic processGO:19015753080.018
regulation of phosphorus metabolic processGO:00511742100.018
Human Rat
appendage developmentGO:00487364010.018
enzyme linked receptor protein signaling pathwayGO:00071671790.017
regulation of cellular ketone metabolic processGO:001056530.017
regulation of cellular amine metabolic processGO:003323830.017
Mouse
leg disc developmentGO:0035218920.017
regulation of organelle organizationGO:00330431960.017
Rat
intracellular signal transductionGO:00355563000.017
Human Mouse Rat
regulation of mitotic cell cycleGO:00073461900.017
Rat
digestive tract morphogenesisGO:00485461270.017
organic substance transportGO:00717022570.017
Human Mouse Rat
regulation of cell proliferationGO:00421271630.017
Mouse Rat
male gamete generationGO:00482322010.017
eggshell formationGO:00307031050.016
response to nitrogen compoundGO:1901698900.016
Human Mouse Rat
regulation of cell deathGO:00109411730.016
salivary gland developmentGO:00074311620.016
spermatogenesisGO:00072832000.016
small molecule metabolic processGO:00442813050.016
Human Rat
appendage morphogenesisGO:00351073970.016
phototaxisGO:0042331210.016
proteolysisGO:00065081920.016
organic acid metabolic processGO:00060821030.015
regulation of multicellular organismal developmentGO:20000264140.015
Mouse
regulation of purine nucleotide biosynthetic processGO:1900371140.015
Human Rat
positive regulation of cell proliferationGO:0008284470.015
Mouse Rat
catabolic processGO:00090564090.015
protein localizationGO:00081042840.015
Human Mouse
photoreceptor cell differentiationGO:00465301700.015
oxoacid metabolic processGO:00434361030.015
cyclic purine nucleotide metabolic processGO:0052652250.015
Human Rat
camp biosynthetic processGO:0006171170.015
Human Rat
regulation of molecular functionGO:00650092170.015
Human Rat
regulation of nucleotide metabolic processGO:0006140620.014
Human Rat
digestive system developmentGO:00551231490.014
wing disc morphogenesisGO:00074723440.014
cell maturationGO:00484691440.014
response to temperature stimulusGO:00092661060.014
taxisGO:00423303040.014
organophosphate metabolic processGO:00196371950.014
Human Rat
sensory organ morphogenesisGO:00905962600.014
nucleoside phosphate metabolic processGO:00067531620.014
Human Rat
regulation of cellular component sizeGO:0032535980.014
regulation of catabolic processGO:00098941700.014
endocytosisGO:00068973100.014
Human Rat
response to organonitrogen compoundGO:0010243750.014
Human Mouse Rat
phototransductionGO:0007602520.014
epithelium migrationGO:00901321480.014
cellular catabolic processGO:00442483720.014
cellular chemical homeostasisGO:0055082400.013
Human Rat
negative regulation of cellular component organizationGO:00511291080.013
imaginal disc derived wing morphogenesisGO:00074763370.013
chorion containing eggshell formationGO:00073041050.013
imaginal disc derived appendage developmentGO:00487373990.013
regulation of immune system processGO:00026821760.013
regulation of gene silencingGO:0060968630.013
cellular homeostasisGO:0019725800.013
Human Rat
regulation of defense responseGO:00313471020.013
detection of stimulus involved in sensory perceptionGO:0050906920.013
protein complex biogenesisGO:00702712010.013
regulation of response to external stimulusGO:00321011150.013
Human Mouse
regulation of phosphate metabolic processGO:00192202100.013
Human Rat
eye developmentGO:00016543230.013
Rat
cell divisionGO:00513012480.013
Human Rat
cellular amino acid metabolic processGO:0006520610.013
camera type eye developmentGO:004301040.013
Rat
rhythmic processGO:00485111060.013
Mouse Rat
retina development in camera type eyeGO:006004140.013
Rat
regulation of response to stressGO:00801342000.012
rna processingGO:00063961470.012
regulation of cell differentiationGO:00455953020.012
Mouse
ion homeostasisGO:0050801550.012
Human Mouse Rat
negative regulation of cell sizeGO:0045792190.012
compound eye photoreceptor cell differentiationGO:00017511400.012
positive regulation of cellular protein metabolic processGO:00322701180.012
Human Rat
regulation of organ growthGO:0046620420.012
regulation of cellular protein metabolic processGO:00322682430.012
Human Rat
leg disc morphogenesisGO:0007478800.012
regulation of cell morphogenesisGO:00226041630.012
regulation of cell shapeGO:00083601130.012
kidney developmentGO:000182230.012
cellular nitrogen compound catabolic processGO:00442701650.012
response to abiotic stimulusGO:00096283410.012
Mouse Rat
male courtship behavior tapping to detect pheromoneGO:001654410.012
response to alcoholGO:0097305950.012
Mouse Rat
negative regulation of cellular biosynthetic processGO:00313272770.011
Human Rat
antimicrobial humoral responseGO:0019730990.011
purine ribonucleoside triphosphate catabolic processGO:00092071080.011
phagocytosisGO:00069092150.011
single organism biosynthetic processGO:00447112060.011
Human Rat
positive regulation of cell migrationGO:003033520.011
regulation of programmed cell deathGO:00430671520.011
single organism cellular localizationGO:19025801800.011
apoptotic processGO:00069151590.011
imaginal disc pattern formationGO:0007447910.011
establishment of protein localizationGO:00451841630.011
Human
phosphorylationGO:00163102940.011
Human Rat
ameboidal type cell migrationGO:00016671510.011
developmental growthGO:00485892800.011
Mouse
negative regulation of cell deathGO:0060548810.011
monocarboxylic acid transportGO:001571830.011
Human
regulation of cell fate specificationGO:0042659270.011
positive regulation of multicellular organismal processGO:00512401430.011
Mouse Rat
embryonic morphogenesisGO:00485982060.011
cyclic nucleotide biosynthetic processGO:0009190250.011
Human Rat
mitotic spindle organizationGO:00070522200.011
positive regulation of cellular component organizationGO:00511301560.011
Rat
reproductive behaviorGO:00190981220.011
chromatin modificationGO:00165681470.010
positive regulation of developmental growthGO:0048639620.010
Mouse
positive regulation of signal transductionGO:00099672230.010
Human Mouse Rat
regulation of response to woundingGO:1903034190.010
neuron projection guidanceGO:00974852410.010
protein heterooligomerizationGO:005129140.010
response to endogenous stimulusGO:00097191190.010
Human Mouse Rat
regulation of intracellular signal transductionGO:19025312360.010
Human Mouse Rat
eye morphogenesisGO:00485922600.010
digestive tract developmentGO:00485651490.010
positive regulation of cell motilityGO:200014730.010
stem cell differentiationGO:00488631170.010
aromatic compound catabolic processGO:00194391660.010

D2R disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.033
musculoskeletal system diseaseDOID:1700.015
nervous system diseaseDOID:86300.014
eye and adnexa diseaseDOID:149200.012
sensory system diseaseDOID:005015500.012
eye diseaseDOID:561400.012