Drosophila melanogaster

17 known processes

Tsp (Dmel_CG11326)

Thrombospondin

(Aliases: CT31613,DTSP,CG11326,SP295,D-TSP,Dmel\CG11326,tsp)

Tsp biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
muscle attachmentGO:0016203360.974
imaginal disc derived appendage developmentGO:00487373990.864
regulation of epithelial cell proliferationGO:005067840.803
Human Mouse
organelle assemblyGO:00709251980.779
muscle structure developmentGO:00610612240.565
imaginal disc derived appendage morphogenesisGO:00351143950.356
axonogenesisGO:00074092900.355
cell adhesionGO:00071551360.304
muscle organ developmentGO:00075171270.283
spermatid differentiationGO:00485151140.277
actomyosin structure organizationGO:0031032560.275
actin filament based processGO:00300292200.269
negative regulation of developmental processGO:00510932010.254
Human Mouse
myofibril assemblyGO:0030239360.252
cell migrationGO:00164772380.250
Human Mouse
skeletal muscle organ developmentGO:0060538480.243
imaginal disc derived wing morphogenesisGO:00074763370.233
agingGO:00075681430.218
determination of muscle attachment siteGO:001620470.215
cell motilityGO:00488702510.215
Human Mouse
negative regulation of cell developmentGO:0010721620.205
cell chemotaxisGO:006032660.199
Human Mouse
protein phosphorylationGO:00064681690.195
Human
regulation of cellular protein metabolic processGO:00322682430.186
Human
digestive tract developmentGO:00485651490.175
regulation of cellular amino acid metabolic processGO:000652100.172
axon developmentGO:00615642970.169
regulation of protein kinase activityGO:0045859510.156
Human
neuron projection guidanceGO:00974852410.141
appendage developmentGO:00487364010.140
biological adhesionGO:00226101380.137
wing disc morphogenesisGO:00074723440.136
regulation of cellular component biogenesisGO:00440872010.134
connective tissue developmentGO:006144830.134
Mouse
negative regulation of cellular protein metabolic processGO:0032269850.131
Human
larval developmentGO:00021641040.129
appendage morphogenesisGO:00351073970.126
cellular macromolecule localizationGO:00707272200.122
axon guidanceGO:00074112330.110
regulation of cellular amine metabolic processGO:003323830.101
posttranscriptional regulation of gene expressionGO:00106081450.095
Human
protein localizationGO:00081042840.092
regulation of transferase activityGO:0051338580.091
Human
camera type eye developmentGO:004301040.088
regulation of cell proliferationGO:00421271630.088
Human Mouse
post embryonic appendage morphogenesisGO:00351203850.086
tube morphogenesisGO:00352391910.086
sarcomere organizationGO:0045214260.083
cellular amine metabolic processGO:0044106120.080
embryonic morphogenesisGO:00485982060.080
multicellular organismal agingGO:00102591400.077
intracellular transportGO:00469072280.075
cellular component assembly involved in morphogenesisGO:00109271510.074
regulation of kinase activityGO:0043549530.072
Human
striated muscle cell differentiationGO:0051146900.070
spermatid developmentGO:0007286980.069
negative regulation of cellular metabolic processGO:00313243820.068
Human
localization of cellGO:00516742570.066
Human Mouse
cellular response to insulin stimulusGO:0032869280.063
single organism intracellular transportGO:19025822070.063
taxisGO:00423303040.063
Human Mouse
open tracheal system developmentGO:00074242040.063
cytoplasmic transportGO:00164821300.059
negative regulation of multicellular organismal processGO:00512411420.059
Human Mouse
actin filament organizationGO:00070151260.059
myoblast fusionGO:0007520430.058
tube developmentGO:00352952440.058
positive regulation of cellular amino acid metabolic processGO:004576400.057
neuron deathGO:0070997270.057
determination of adult lifespanGO:00083401370.057
peptidyl tyrosine phosphorylationGO:0018108240.056
regulation of anatomical structure sizeGO:00900661630.055
chemotaxisGO:00069352490.054
Human Mouse
mesoderm developmentGO:0007498780.053
embryonic axis specificationGO:00005781070.053
endomembrane system organizationGO:00102561190.052
sensory organ morphogenesisGO:00905962600.050
regulation of catalytic activityGO:00507901850.049
Human
regulation of chemotaxisGO:0050920120.048
Human Mouse
striated muscle cell developmentGO:0055002500.048
regulation of neuron deathGO:1901214260.047
regulation of multicellular organism growthGO:0040014400.047
tripartite regional subdivisionGO:00073511030.047
synapse organizationGO:00508081960.046
regulation of protein metabolic processGO:00512462560.046
Human
cellular protein modification processGO:00064644380.045
Human
glial cell migrationGO:0008347310.043
peptidyl tyrosine modificationGO:0018212240.043
morphogenesis of an epitheliumGO:00020092760.043
spermatogenesisGO:00072832000.042
nucleocytoplasmic transportGO:0006913720.041
organ growthGO:0035265560.041
Mouse
regulation of cellular component movementGO:0051270420.041
Human Mouse
response to monosaccharideGO:003428440.041
Human
cellular protein localizationGO:00346131600.040
regulation of response to external stimulusGO:00321011150.040
Human Mouse
positive regulation of cellular amine metabolic processGO:003324000.040
protein transportGO:00150311550.040
substrate adhesion dependent cell spreadingGO:003444620.040
regulation of neurogenesisGO:00507671580.040
embryonic development via the syncytial blastodermGO:00017001480.039
response to peptide hormoneGO:0043434290.039
amine metabolic processGO:0009308120.038
regulation of locomotionGO:0040012420.037
Human Mouse
tissue morphogenesisGO:00487292970.037
male gamete generationGO:00482322010.037
negative regulation of response to stimulusGO:00485852580.037
Human
motor neuron axon guidanceGO:0008045580.037
eye developmentGO:00016543230.036
response to purine containing compoundGO:0014074120.036
circulatory system developmentGO:0072359820.036
Human Mouse
respiratory system developmentGO:00605412130.036
positive regulation of molecular functionGO:00440931360.035
Human
imaginal disc derived wing margin morphogenesisGO:0008587410.034
cellular ketone metabolic processGO:0042180240.034
peptidyl amino acid modificationGO:00181931050.034
multicellular organismal signalingGO:0035637120.034
ameboidal type cell migrationGO:00016671510.034
Human
cellular response to molecule of bacterial originGO:007121930.034
phosphorylationGO:00163102940.033
Human
digestive system developmentGO:00551231490.033
regulation of multicellular organismal developmentGO:20000264140.032
Human Mouse
body morphogenesisGO:001017120.032
positive regulation of peptidyl tyrosine phosphorylationGO:005073140.032
negative regulation of phosphorylationGO:0042326350.031
larval somatic muscle developmentGO:0007526190.031
photoreceptor cell axon guidanceGO:0072499230.031
single organism cell adhesionGO:0098602470.031
regulation of cell migrationGO:0030334220.031
Human Mouse
nuclear transportGO:0051169720.030
negative regulation of transferase activityGO:0051348180.030
regulation of cellular ketone metabolic processGO:001056530.030
response to ethanolGO:0045471590.030
morphogenesis of a branching structureGO:0001763450.030
negative regulation of epithelial cell proliferationGO:005068040.030
Human Mouse
regulation of cell morphogenesis involved in differentiationGO:0010769610.030
regulation of developmental growthGO:00486381740.030
response to organic substanceGO:00100332840.029
Human Mouse
developmental growthGO:00485892800.029
Mouse
muscle cell developmentGO:0055001500.029
mapk cascadeGO:00001651070.029
Human
positive regulation of transferase activityGO:0051347260.029
Human
anterior posterior axis specificationGO:00099481090.029
regulation of reproductive processGO:2000241540.029
negative regulation of gene expressionGO:00106293870.029
Human
establishment of protein localizationGO:00451841630.029
positive regulation of protein modification processGO:0031401580.028
Human
metal ion transportGO:0030001740.028
negative regulation of nervous system developmentGO:0051961920.028
neuronal action potentialGO:0019228100.028
cellular amino acid metabolic processGO:0006520610.028
apposition of dorsal and ventral imaginal disc derived wing surfacesGO:0007475150.028
regulation of localizationGO:00328792750.027
Human Mouse
response to abiotic stimulusGO:00096283410.027
endocytosisGO:00068973100.027
Human
ectodermal placode morphogenesisGO:007169740.027
negative regulation of kinase activityGO:0033673160.027
muscle cell differentiationGO:00426921030.027
positive regulation of response to stimulusGO:00485843230.027
Human Mouse
endodermal cell differentiationGO:003598730.026
regulation of cell substrate adhesionGO:001081020.026
Human Mouse
skin developmentGO:0043588650.026
multicellular organismal homeostasisGO:0048871410.026
larval visceral muscle developmentGO:000752390.026
somatic muscle developmentGO:0007525660.026
regulation of mitotic cell cycleGO:00073461900.025
digestive tract morphogenesisGO:00485461270.025
nuclear exportGO:0051168240.025
chromosome segregationGO:00070591570.025
positive regulation of protein phosphorylationGO:0001934340.025
Human
positive regulation of catalytic activityGO:00430851180.024
Human
nucleoside triphosphate catabolic processGO:00091431080.024
positive regulation of developmental processGO:00510941430.024
Human
anatomical structure homeostasisGO:0060249970.024
cell projection assemblyGO:0030031940.024
protein localization to organelleGO:0033365820.024
dorsal ventral pattern formationGO:00099531330.024
regulation of cell adhesionGO:0030155270.024
Human Mouse
regulation of notch signaling pathwayGO:00085931000.024
positive regulation of cellular component biogenesisGO:0044089800.023
synapse assemblyGO:00074161430.023
regulation of neuron apoptotic processGO:0043523160.022
regulation of cell differentiationGO:00455953020.022
phagocytosisGO:00069092150.021
Human
proteolysisGO:00065081920.021
Human
negative regulation of protein metabolic processGO:0051248850.021
Human
response to organonitrogen compoundGO:0010243750.021
specification of organ identityGO:001009230.020
peripheral nervous system developmentGO:0007422520.020
epithelial cell proliferationGO:0050673150.020
Human Mouse
positive regulation of cell deathGO:0010942690.020
Human
embryonic pattern specificationGO:00098801740.020
regulation of phosphorus metabolic processGO:00511742100.020
Human
retina development in camera type eyeGO:006004140.020
compound eye developmentGO:00487493070.020
single organismal cell cell adhesionGO:0016337450.020
ribonucleotide metabolic processGO:00092591450.019
Human
regulation of rna splicingGO:0043484690.019
positive regulation of cellular protein metabolic processGO:00322701180.019
Human
cellular response to endogenous stimulusGO:0071495800.019
Human Mouse
regulation of mitosisGO:0007088560.019
rna processingGO:00063961470.019
positive regulation of cellular component organizationGO:00511301560.019
positive regulation of signalingGO:00230562430.019
Human Mouse
purine ribonucleoside triphosphate catabolic processGO:00092071080.019
protein catabolic processGO:00301631010.019
nucleoside triphosphate metabolic processGO:00091411200.019
regulation of phosphorylationGO:00423251470.019
Human
neural precursor cell proliferationGO:0061351750.018
response to growth factorGO:0070848310.018
Human Mouse
regulation of cell developmentGO:00602842150.018
regulation of cell sizeGO:0008361630.018
regulation of nervous system developmentGO:00519602480.018
regulation of protein transportGO:0051223570.018
negative regulation of cell proliferationGO:0008285690.018
Human Mouse
protein modification processGO:00362114380.017
Human
regulation of molecular functionGO:00650092170.017
Human
positive regulation of cell migrationGO:003033520.017
Human Mouse
cellular response to peptide hormone stimulusGO:0071375280.017
gastrulationGO:0007369700.017
neurological system processGO:00508773580.017
syncytium formation by plasma membrane fusionGO:0000768430.017
regulation of neuron projection developmentGO:0010975690.017
erbb signaling pathwayGO:0038127580.017
gene silencingGO:00164581380.017
segmentationGO:00352822070.017
regulation of map kinase activityGO:0043405170.017
Human
cell junction assemblyGO:0034329420.016
mesoderm formationGO:0001707210.016
negative regulation of neurogenesisGO:0050768530.016
regulation of proteolysisGO:0030162870.016
Human
carboxylic acid metabolic processGO:0019752920.016
response to organophosphorusGO:004668320.016
cell junction organizationGO:0034330570.016
regulation of protein phosphorylationGO:0001932640.016
Human
action potentialGO:0001508130.016
positive regulation of cell proliferationGO:0008284470.016
oocyte maturationGO:000155630.016
cellular response to nitrogen compoundGO:1901699510.016
Mouse
nuclear importGO:0051170510.016
regulation of cell motilityGO:2000145230.016
Human Mouse
cell proliferationGO:00082832990.015
Human Mouse
vesicle mediated transportGO:00161923810.015
Human
positive regulation of macromolecule metabolic processGO:00106044050.015
Human
ribonucleoside metabolic processGO:00091191270.015
negative regulation of protein modification processGO:0031400290.015
protein targetingGO:0006605640.015
negative regulation of phosphate metabolic processGO:0045936450.015
positive regulation of cell motilityGO:200014730.015
Human Mouse
germ band shorteningGO:0007390190.015
signal transduction by phosphorylationGO:00230141070.015
Human
mesodermal cell migrationGO:000807870.015
cell cell junction assemblyGO:0007043380.015
filopodium assemblyGO:0046847330.015
cellular response to oxygen containing compoundGO:1901701790.015
Mouse
actin cytoskeleton organizationGO:00300362060.015
neuron apoptotic processGO:0051402170.015
developmental maturationGO:00217001720.015
Mouse
stem cell developmentGO:0048864790.015
golgi organizationGO:0007030660.014
microtubule bundle formationGO:0001578270.014
cardiovascular system developmentGO:0072358820.014
Human Mouse
regulation of cell projection organizationGO:0031344920.014
organelle fissionGO:00482853400.014
regulation of cellular component sizeGO:0032535980.014
positive regulation of gene expressionGO:00106282900.014
Human
extracellular structure organizationGO:0043062460.014
negative regulation of catalytic activityGO:0043086420.014
Human
germ line stem cell maintenanceGO:0030718500.014
axis elongationGO:000340130.014
response to hypoxiaGO:0001666530.014
response to lipopolysaccharideGO:003249640.014
sister chromatid segregationGO:0000819920.014
kidney epithelium developmentGO:007207330.014
cell cell adhesion via plasma membrane adhesion moleculesGO:0098742260.014
positive regulation of transcription factor import into nucleusGO:0042993190.014
establishment of localization in cellGO:00516494020.014
cell migration involved in gastrulationGO:004207490.014
response to decreased oxygen levelsGO:0036293580.014
transmission of nerve impulseGO:0019226120.014
endoderm formationGO:000170630.014
negative regulation of molecular functionGO:0044092510.014
Human
gliogenesisGO:0042063800.014
response to lithium ionGO:001022610.014
regulation of translationGO:0006417560.013
Human
neuroblast proliferationGO:0007405740.013
regulation of neuron differentiationGO:00456641030.013
forebrain developmentGO:003090020.013
axon ensheathmentGO:0008366100.013
protein localization to nucleusGO:0034504550.013
bmp signaling pathwayGO:0030509270.013
ensheathment of neuronsGO:0007272100.013
cell cell signaling involved in cell fate commitmentGO:00451682100.013
regulation of protein modification processGO:00313991120.013
Human
cranial nerve developmentGO:002154510.013
negative regulation of signal transductionGO:00099682060.013
Human
positive regulation of developmental growthGO:0048639620.013
regulation of cell morphogenesisGO:00226041630.013
glial cell developmentGO:0021782270.013
outflow tract morphogenesisGO:000315140.013
Mouse
notch signaling pathwayGO:00072191200.013
positive regulation of protein kinase activityGO:0045860250.013
Human
activation of protein kinase activityGO:0032147120.012
Human
tissue homeostasisGO:0001894360.012
epithelial cell migration open tracheal systemGO:0007427320.012
regulation of membrane potentialGO:0042391350.012
mitotic nuclear divisionGO:00070672130.012
establishment of organelle localizationGO:00516561220.012
negative regulation of cell cycle phase transitionGO:19019881030.012
response to oxygen levelsGO:0070482590.012
nephron developmentGO:007200630.012
positive regulation of growthGO:0045927750.012
positive regulation of kinase activityGO:0033674250.012
Human
anterior posterior pattern specificationGO:00099521360.012
germ line cyst formationGO:0048134440.012
positive regulation of cell projection organizationGO:0031346290.012
dorsal ventral pattern formation imaginal discGO:0007450510.012
maintenance of locationGO:0051235730.012
endodermal cell fate commitmentGO:000171130.012
negative regulation of cell cycle processGO:00109481090.012
response to glucoseGO:000974920.012
Human
camera type eye morphogenesisGO:004859320.012
positive regulation of immune system processGO:0002684680.012
Human Mouse
regulation of behaviorGO:0050795750.012
Human Mouse
regulation of mrna metabolic processGO:1903311720.012
purine containing compound catabolic processGO:00725231120.012
cellular response to external stimulusGO:0071496660.011
positive regulation of rna metabolic processGO:00512542710.011
cell cycle arrestGO:000705040.011
Human
cell deathGO:00082192790.011
Human
negative regulation of cell motilityGO:200014650.011
Human
regulation of mitotic cell cycle phase transitionGO:19019901300.011
formation of primary germ layerGO:0001704240.011
negative regulation of cell cycleGO:00457861160.011
Human
intracellular protein transmembrane transportGO:006500240.011
negative regulation of phosphorus metabolic processGO:0010563450.011
kidney developmentGO:000182230.011
nuclear divisionGO:00002803320.011
cellular response to oxygen levelsGO:0071453300.011
cuticle developmentGO:0042335860.011
positive regulation of signal transductionGO:00099672230.011
Human Mouse
regulation of transcription from rna polymerase ii promoterGO:00063573780.011
telencephalon developmentGO:002153720.011
lateral inhibitionGO:00463312060.011
cellular response to fibroblast growth factor stimulusGO:0044344100.011
Human
purine nucleoside triphosphate catabolic processGO:00091461080.011
nucleoside phosphate metabolic processGO:00067531620.011
Human
cell divisionGO:00513012480.011
response to peptideGO:1901652290.011
regulation of receptor activityGO:0010469100.010
regulation of protein serine threonine kinase activityGO:0071900250.010
Human
nucleoside metabolic processGO:00091161270.010
lipid storageGO:0019915380.010
intracellular protein transportGO:00068861040.010
positive regulation of mapk cascadeGO:0043410630.010
Human
translationGO:0006412690.010
Human
striated muscle myosin thick filament assemblyGO:007168830.010
regulation of neural precursor cell proliferationGO:2000177350.010
negative regulation of cellular biosynthetic processGO:00313272770.010
negative regulation of cellular component organizationGO:00511291080.010
dendrite developmentGO:00163582040.010

Tsp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cardiovascular system diseaseDOID:128700.041
vascular diseaseDOID:17800.041
disease of anatomical entityDOID:700.041
musculoskeletal system diseaseDOID:1700.022
cardiomyopathyDOID:005070000.022
myopathyDOID:42300.022
muscle tissue diseaseDOID:6600.022
intrinsic cardiomyopathyDOID:006003600.022
heart diseaseDOID:11400.022
muscular diseaseDOID:008000000.022
large intestine cancerDOID:567200.016
organ system cancerDOID:005068600.016
gastrointestinal system cancerDOID:311900.016
disease of cellular proliferationDOID:1456600.016
intestinal cancerDOID:1015500.016
cancerDOID:16200.016
colorectal cancerDOID:925600.016