| histone modification | GO:0016570 | 106 | 0.919 | |
| protein acetylation | GO:0006473 | 39 | 0.914 | |
| covalent chromatin modification | GO:0016569 | 106 | 0.912 | |
| peptidyl lysine modification | GO:0018205 | 57 | 0.841 | |
| chromatin organization | GO:0006325 | 207 | 0.825 | |
| histone h4 acetylation | GO:0043967 | 13 | 0.779 | Human |
| positive regulation of rna metabolic process | GO:0051254 | 271 | 0.759 | Mouse |
| histone acetylation | GO:0016573 | 38 | 0.685 | |
| protein modification process | GO:0036211 | 438 | 0.658 | |
| positive regulation of gene expression | GO:0010628 | 290 | 0.608 | Mouse |
| internal peptidyl lysine acetylation | GO:0018393 | 38 | 0.588 | |
| protein acylation | GO:0043543 | 42 | 0.559 | |
| positive regulation of transcription dna templated | GO:0045893 | 266 | 0.538 | Mouse |
| chromatin remodeling | GO:0006338 | 72 | 0.475 | |
| enzyme linked receptor protein signaling pathway | GO:0007167 | 179 | 0.444 | |
| imaginal disc derived appendage development | GO:0048737 | 399 | 0.443 | |
| chromatin modification | GO:0016568 | 147 | 0.437 | |
| negative regulation of cellular metabolic process | GO:0031324 | 382 | 0.407 | |
| wing disc morphogenesis | GO:0007472 | 344 | 0.357 | |
| positive regulation of rna biosynthetic process | GO:1902680 | 266 | 0.347 | Mouse |
| positive regulation of macromolecule metabolic process | GO:0010604 | 405 | 0.338 | Mouse |
| regionalization | GO:0003002 | 416 | 0.329 | |
| positive regulation of biosynthetic process | GO:0009891 | 316 | 0.320 | Mouse |
| peptidyl amino acid modification | GO:0018193 | 105 | 0.304 | |
| chromosome organization | GO:0051276 | 360 | 0.304 | |
| cellular protein modification process | GO:0006464 | 438 | 0.293 | |
| cellular component assembly involved in morphogenesis | GO:0010927 | 151 | 0.288 | |
| peptidyl lysine acetylation | GO:0018394 | 39 | 0.275 | |
| appendage morphogenesis | GO:0035107 | 397 | 0.206 | |
| alternative mrna splicing via spliceosome | GO:0000380 | 60 | 0.190 | |
| negative regulation of rna metabolic process | GO:0051253 | 251 | 0.187 | |
| internal protein amino acid acetylation | GO:0006475 | 38 | 0.183 | |
| negative regulation of cell cycle process | GO:0010948 | 109 | 0.183 | |
| compound eye photoreceptor cell differentiation | GO:0001751 | 140 | 0.181 | |
| positive regulation of nucleic acid templated transcription | GO:1903508 | 266 | 0.180 | Mouse |
| negative regulation of gene expression | GO:0010629 | 387 | 0.166 | |
| vesicle mediated transport | GO:0016192 | 381 | 0.166 | |
| cellular amino acid metabolic process | GO:0006520 | 61 | 0.154 | |
| positive regulation of cellular biosynthetic process | GO:0031328 | 316 | 0.150 | Mouse |
| imaginal disc derived wing vein morphogenesis | GO:0008586 | 44 | 0.150 | |
| cellular response to dna damage stimulus | GO:0006974 | 223 | 0.150 | |
| intracellular signal transduction | GO:0035556 | 300 | 0.149 | |
| imaginal disc derived wing morphogenesis | GO:0007476 | 337 | 0.148 | |
| transcription from rna polymerase ii promoter | GO:0006366 | 368 | 0.147 | Mouse |
| establishment of localization in cell | GO:0051649 | 402 | 0.145 | |
| dendrite morphogenesis | GO:0048813 | 199 | 0.142 | |
| negative regulation of cellular biosynthetic process | GO:0031327 | 277 | 0.141 | |
| muscle cell development | GO:0055001 | 50 | 0.139 | |
| open tracheal system development | GO:0007424 | 204 | 0.139 | |
| transmembrane receptor protein tyrosine kinase signaling pathway | GO:0007169 | 116 | 0.137 | |
| regulation of protein modification process | GO:0031399 | 112 | 0.135 | |
| stem cell differentiation | GO:0048863 | 117 | 0.134 | |
| organelle assembly | GO:0070925 | 198 | 0.133 | |
| post embryonic appendage morphogenesis | GO:0035120 | 385 | 0.131 | |
| muscle cell differentiation | GO:0042692 | 103 | 0.128 | |
| methylation | GO:0032259 | 47 | 0.127 | |
| imaginal disc derived appendage morphogenesis | GO:0035114 | 395 | 0.122 | |
| stem cell maintenance | GO:0019827 | 67 | 0.118 | |
| dendrite development | GO:0016358 | 204 | 0.117 | |
| response to abiotic stimulus | GO:0009628 | 341 | 0.115 | |
| molting cycle | GO:0042303 | 56 | 0.115 | |
| axon development | GO:0061564 | 297 | 0.114 | |
| positive regulation of nucleobase containing compound metabolic process | GO:0045935 | 332 | 0.111 | Mouse |
| positive regulation of macromolecule biosynthetic process | GO:0010557 | 283 | 0.111 | Mouse |
| rna splicing | GO:0008380 | 83 | 0.109 | |
| regulation of multicellular organismal development | GO:2000026 | 414 | 0.102 | Worm |
| regulation of cellular amine metabolic process | GO:0033238 | 3 | 0.101 | |
| appendage development | GO:0048736 | 401 | 0.101 | |
| cell motility | GO:0048870 | 251 | 0.094 | Worm |
| actin cytoskeleton organization | GO:0030036 | 206 | 0.092 | |
| positive regulation of nitrogen compound metabolic process | GO:0051173 | 354 | 0.086 | Mouse |
| regulation of nervous system development | GO:0051960 | 248 | 0.086 | |
| regulation of cellular protein metabolic process | GO:0032268 | 243 | 0.085 | |
| proteolysis | GO:0006508 | 192 | 0.084 | |
| eye photoreceptor cell differentiation | GO:0001754 | 145 | 0.080 | |
| cytoplasmic transport | GO:0016482 | 130 | 0.079 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 3 | 0.079 | Mouse |
| negative regulation of nitrogen compound metabolic process | GO:0051172 | 265 | 0.078 | |
| body morphogenesis | GO:0010171 | 2 | 0.076 | |
| immune response | GO:0006955 | 246 | 0.074 | |
| regulation of transcription from rna polymerase ii promoter | GO:0006357 | 378 | 0.074 | Mouse |
| spermatogenesis | GO:0007283 | 200 | 0.071 | |
| axonogenesis | GO:0007409 | 290 | 0.070 | |
| dna biosynthetic process | GO:0071897 | 24 | 0.069 | |
| imaginal disc derived wing vein specification | GO:0007474 | 48 | 0.069 | |
| response to radiation | GO:0009314 | 155 | 0.068 | |
| negative regulation of nucleobase containing compound metabolic process | GO:0045934 | 261 | 0.068 | |
| striated muscle cell development | GO:0055002 | 50 | 0.067 | |
| neuronal stem cell maintenance | GO:0097150 | 4 | 0.066 | |
| negative regulation of cellular macromolecule biosynthetic process | GO:2000113 | 267 | 0.064 | |
| positive regulation of signaling | GO:0023056 | 243 | 0.063 | |
| central nervous system development | GO:0007417 | 201 | 0.061 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 0 | 0.060 | |
| photoreceptor cell differentiation | GO:0046530 | 170 | 0.058 | |
| regulation of rna splicing | GO:0043484 | 69 | 0.056 | |
| intracellular transport | GO:0046907 | 228 | 0.055 | |
| histone h3 acetylation | GO:0043966 | 11 | 0.051 | Human |
| establishment of protein localization | GO:0045184 | 163 | 0.050 | |
| regulation of small gtpase mediated signal transduction | GO:0051056 | 93 | 0.050 | |
| rna splicing via transesterification reactions with bulged adenosine as nucleophile | GO:0000377 | 73 | 0.048 | |
| phosphorylation | GO:0016310 | 294 | 0.047 | |
| negative regulation of developmental process | GO:0051093 | 201 | 0.047 | Worm |
| cellular response to chemical stimulus | GO:0070887 | 199 | 0.047 | |
| amine metabolic process | GO:0009308 | 12 | 0.046 | |
| regulation of cell differentiation | GO:0045595 | 302 | 0.046 | |
| regulation of erbb signaling pathway | GO:1901184 | 42 | 0.046 | |
| nucleosome organization | GO:0034728 | 59 | 0.044 | |
| mrna splicing via spliceosome | GO:0000398 | 73 | 0.043 | |
| muscle structure development | GO:0061061 | 224 | 0.041 | |
| dna damage checkpoint | GO:0000077 | 78 | 0.040 | |
| negative regulation of cell cycle | GO:0045786 | 116 | 0.040 | |
| rna processing | GO:0006396 | 147 | 0.040 | |
| actomyosin structure organization | GO:0031032 | 56 | 0.039 | |
| regulation of protein metabolic process | GO:0051246 | 256 | 0.039 | |
| transmembrane transport | GO:0055085 | 139 | 0.039 | |
| cellular amine metabolic process | GO:0044106 | 12 | 0.038 | |
| immune system process | GO:0002376 | 347 | 0.037 | |
| phagocytosis | GO:0006909 | 215 | 0.037 | |
| myofibril assembly | GO:0030239 | 36 | 0.037 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 79 | 0.036 | |
| single organism intracellular transport | GO:1902582 | 207 | 0.036 | |
| postreplication repair | GO:0006301 | 2 | 0.036 | |
| positive regulation of transcription from rna polymerase ii promoter | GO:0045944 | 204 | 0.035 | Mouse |
| response to endogenous stimulus | GO:0009719 | 119 | 0.035 | |
| epidermal growth factor receptor signaling pathway | GO:0007173 | 58 | 0.034 | |
| positive regulation of signal transduction | GO:0009967 | 223 | 0.034 | |
| dorsal ventral pattern formation | GO:0009953 | 133 | 0.033 | |
| organic acid metabolic process | GO:0006082 | 103 | 0.033 | |
| anterior posterior axis specification | GO:0009948 | 109 | 0.032 | |
| regulation of bmp signaling pathway | GO:0030510 | 23 | 0.032 | |
| regulation of immune response | GO:0050776 | 118 | 0.032 | |
| cellular protein localization | GO:0034613 | 160 | 0.032 | |
| respiratory system development | GO:0060541 | 213 | 0.031 | |
| neuron fate commitment | GO:0048663 | 50 | 0.030 | |
| nucleocytoplasmic transport | GO:0006913 | 72 | 0.029 | |
| axon guidance | GO:0007411 | 233 | 0.028 | |
| protein catabolic process | GO:0030163 | 101 | 0.028 | |
| defense response | GO:0006952 | 300 | 0.028 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 130 | 0.028 | |
| spindle organization | GO:0007051 | 253 | 0.028 | |
| inter male aggressive behavior | GO:0002121 | 60 | 0.028 | |
| proteasomal protein catabolic process | GO:0010498 | 59 | 0.028 | |
| mrna metabolic process | GO:0016071 | 124 | 0.028 | |
| regulation of immune system process | GO:0002682 | 176 | 0.027 | |
| positive regulation of cell communication | GO:0010647 | 250 | 0.027 | |
| tube morphogenesis | GO:0035239 | 191 | 0.026 | |
| regulation of gene expression epigenetic | GO:0040029 | 128 | 0.026 | |
| male gamete generation | GO:0048232 | 201 | 0.026 | |
| regulation of mrna splicing via spliceosome | GO:0048024 | 64 | 0.025 | |
| carboxylic acid metabolic process | GO:0019752 | 92 | 0.025 | |
| erbb signaling pathway | GO:0038127 | 58 | 0.025 | |
| forebrain development | GO:0030900 | 2 | 0.025 | |
| regulation of phosphorylation | GO:0042325 | 147 | 0.025 | |
| regulation of phosphorus metabolic process | GO:0051174 | 210 | 0.024 | |
| embryo development ending in birth or egg hatching | GO:0009792 | 152 | 0.024 | |
| macromolecule methylation | GO:0043414 | 45 | 0.024 | |
| regulation of intracellular signal transduction | GO:1902531 | 236 | 0.022 | |
| neurological system process | GO:0050877 | 358 | 0.021 | |
| negative regulation of cell differentiation | GO:0045596 | 143 | 0.021 | |
| axis specification | GO:0009798 | 167 | 0.021 | |
| stem cell development | GO:0048864 | 79 | 0.021 | |
| cell fate specification | GO:0001708 | 71 | 0.021 | |
| organonitrogen compound metabolic process | GO:1901564 | 318 | 0.021 | |
| cellular macromolecule catabolic process | GO:0044265 | 136 | 0.021 | |
| head development | GO:0060322 | 135 | 0.020 | |
| germ line stem cell maintenance | GO:0030718 | 50 | 0.020 | |
| positive regulation of immune response | GO:0050778 | 63 | 0.020 | |
| actin filament based process | GO:0030029 | 220 | 0.020 | |
| nuclear export | GO:0051168 | 24 | 0.020 | |
| response to alcohol | GO:0097305 | 95 | 0.020 | |
| translesion synthesis | GO:0019985 | 2 | 0.020 | |
| positive regulation of response to stimulus | GO:0048584 | 323 | 0.019 | |
| negative regulation of nucleic acid templated transcription | GO:1903507 | 240 | 0.019 | |
| regulation of notch signaling pathway | GO:0008593 | 100 | 0.019 | |
| negative regulation of signal transduction | GO:0009968 | 206 | 0.019 | |
| protein alkylation | GO:0008213 | 43 | 0.019 | |
| spindle assembly involved in mitosis | GO:0090307 | 50 | 0.019 | |
| regulation of transport | GO:0051049 | 181 | 0.019 | |
| striated muscle cell differentiation | GO:0051146 | 90 | 0.019 | |
| response to organic substance | GO:0010033 | 284 | 0.019 | |
| olfactory behavior | GO:0042048 | 97 | 0.019 | |
| nuclear transport | GO:0051169 | 72 | 0.018 | |
| positive regulation of immune system process | GO:0002684 | 68 | 0.018 | |
| protein transport | GO:0015031 | 155 | 0.018 | |
| negative regulation of protein modification process | GO:0031400 | 29 | 0.018 | |
| protein localization to organelle | GO:0033365 | 82 | 0.018 | |
| organic substance transport | GO:0071702 | 257 | 0.018 | |
| embryonic pattern specification | GO:0009880 | 174 | 0.018 | |
| negative regulation of protein metabolic process | GO:0051248 | 85 | 0.018 | |
| regulation of alternative mrna splicing via spliceosome | GO:0000381 | 60 | 0.018 | |
| protein complex assembly | GO:0006461 | 200 | 0.018 | |
| positive regulation of histone deacetylation | GO:0031065 | 2 | 0.018 | |
| regulation of response to stress | GO:0080134 | 200 | 0.018 | |
| cell death | GO:0008219 | 279 | 0.017 | Worm |
| protein targeting to nucleus | GO:0044744 | 51 | 0.017 | |
| endocytosis | GO:0006897 | 310 | 0.017 | |
| defense response to other organism | GO:0098542 | 225 | 0.017 | |
| apoptotic process | GO:0006915 | 159 | 0.017 | Worm |
| regulation of phosphatase activity | GO:0010921 | 3 | 0.016 | |
| negative regulation of rna biosynthetic process | GO:1902679 | 240 | 0.016 | |
| gtp metabolic process | GO:0046039 | 72 | 0.016 | |
| oxoacid metabolic process | GO:0043436 | 103 | 0.016 | |
| negative regulation of transcription from rna polymerase ii promoter | GO:0000122 | 119 | 0.016 | |
| developmental maturation | GO:0021700 | 172 | 0.016 | |
| hematopoietic progenitor cell differentiation | GO:0002244 | 1 | 0.016 | |
| macromolecule catabolic process | GO:0009057 | 161 | 0.016 | |
| protein maturation | GO:0051604 | 71 | 0.015 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 78 | 0.015 | |
| regulation of nucleocytoplasmic transport | GO:0046822 | 35 | 0.015 | |
| rna splicing via transesterification reactions | GO:0000375 | 73 | 0.015 | |
| nucleobase containing compound transport | GO:0015931 | 56 | 0.015 | |
| organelle localization | GO:0051640 | 148 | 0.015 | |
| aging | GO:0007568 | 143 | 0.015 | Worm |
| regulation of mrna metabolic process | GO:1903311 | 72 | 0.014 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 85 | 0.014 | |
| single organism cellular localization | GO:1902580 | 180 | 0.014 | |
| mitotic cytokinesis | GO:0000281 | 50 | 0.014 | |
| larval development | GO:0002164 | 104 | 0.014 | Worm |
| establishment or maintenance of cell polarity | GO:0007163 | 167 | 0.014 | |
| negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway | GO:0090101 | 18 | 0.014 | |
| regulation of cell cycle phase transition | GO:1901987 | 130 | 0.014 | |
| negative regulation of response to stimulus | GO:0048585 | 258 | 0.014 | |
| negative regulation of transcription dna templated | GO:0045892 | 237 | 0.014 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 0 | 0.014 | |
| mrna processing | GO:0006397 | 104 | 0.013 | |
| small molecule metabolic process | GO:0044281 | 305 | 0.013 | Mouse |
| positive regulation of protein deacetylation | GO:0090312 | 2 | 0.013 | |
| regulation of molecular function | GO:0065009 | 217 | 0.013 | |
| histone deubiquitination | GO:0016578 | 8 | 0.013 | |
| neuron recognition | GO:0008038 | 101 | 0.013 | |
| negative regulation of biosynthetic process | GO:0009890 | 277 | 0.013 | |
| positive regulation of cellular component organization | GO:0051130 | 156 | 0.013 | |
| cell cycle checkpoint | GO:0000075 | 95 | 0.013 | |
| compound eye development | GO:0048749 | 307 | 0.013 | |
| regulation of neuron differentiation | GO:0045664 | 103 | 0.013 | |
| protein processing | GO:0016485 | 68 | 0.013 | |
| intracellular protein transport | GO:0006886 | 104 | 0.013 | |
| mitochondrion organization | GO:0007005 | 65 | 0.013 | |
| cellular macromolecule localization | GO:0070727 | 220 | 0.012 | |
| neuron projection guidance | GO:0097485 | 241 | 0.012 | |
| regulation of hemocyte proliferation | GO:0035206 | 37 | 0.012 | |
| nucleobase containing compound catabolic process | GO:0034655 | 165 | 0.012 | |
| bmp signaling pathway | GO:0030509 | 27 | 0.012 | |
| protein phosphorylation | GO:0006468 | 169 | 0.012 | |
| cell migration | GO:0016477 | 238 | 0.012 | Worm |
| negative regulation of macromolecule biosynthetic process | GO:0010558 | 270 | 0.011 | |
| oocyte development | GO:0048599 | 124 | 0.011 | |
| exocrine system development | GO:0035272 | 162 | 0.011 | |
| response to biotic stimulus | GO:0009607 | 294 | 0.011 | |
| regulation of meiosis | GO:0040020 | 3 | 0.011 | |
| eye photoreceptor cell fate commitment | GO:0042706 | 37 | 0.011 | |
| salivary gland development | GO:0007431 | 162 | 0.011 | |
| regulation of cytoplasmic transport | GO:1903649 | 47 | 0.011 | |
| positive regulation of notch signaling pathway | GO:0045747 | 34 | 0.011 | |
| segmentation | GO:0035282 | 207 | 0.011 | |
| dna metabolic process | GO:0006259 | 227 | 0.011 | |
| ras protein signal transduction | GO:0007265 | 88 | 0.011 | |
| hindbrain development | GO:0030902 | 2 | 0.011 | |
| anatomical structure homeostasis | GO:0060249 | 97 | 0.011 | |
| protein targeting | GO:0006605 | 64 | 0.010 | |
| notch signaling pathway | GO:0007219 | 120 | 0.010 | |
| cell maturation | GO:0048469 | 144 | 0.010 | |
| striated muscle myosin thick filament assembly | GO:0071688 | 3 | 0.010 | |
| regulation of phosphate metabolic process | GO:0019220 | 210 | 0.010 | |
| chemosensory behavior | GO:0007635 | 106 | 0.010 | |
| cellular protein catabolic process | GO:0044257 | 83 | 0.010 | |