Drosophila melanogaster

15 known processes

Pde9 (Dmel_CG42276)

Phosphodiesterase 9

(Aliases: Dmel_CG32648,Dmel\CG42276,CG1627,Dmel_CG3754,CG3761,CG42276,PDE9,CG3754,CG3765,CG32648)

Pde9 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
vesicle mediated transportGO:00161923810.078
response to external biotic stimulusGO:00432072930.076
organic acid metabolic processGO:00060821030.069
neurological system processGO:00508773580.067
establishment of localization in cellGO:00516494020.064
regulation of localizationGO:00328792750.056
single organism behaviorGO:00447083910.052
imaginal disc derived appendage developmentGO:00487373990.050
positive regulation of signal transductionGO:00099672230.048
imaginal disc derived appendage morphogenesisGO:00351143950.047
positive regulation of response to stimulusGO:00485843230.046
appendage morphogenesisGO:00351073970.045
protein modification processGO:00362114380.044
endocytosisGO:00068973100.042
positive regulation of nitrogen compound metabolic processGO:00511733540.041
neuron recognitionGO:00080381010.041
regulation of neurogenesisGO:00507671580.040
regulation of transportGO:00510491810.039
phagocytosisGO:00069092150.039
axon developmentGO:00615642970.038
innate immune responseGO:00450871440.037
deathGO:00162652840.037
adult behaviorGO:00305341370.036
oxoacid metabolic processGO:00434361030.036
carboxylic acid metabolic processGO:0019752920.036
axis specificationGO:00097981670.035
imaginal disc derived wing morphogenesisGO:00074763370.035
small gtpase mediated signal transductionGO:0007264880.035
positive regulation of nucleobase containing compound metabolic processGO:00459353320.035
intracellular signal transductionGO:00355563000.035
cellular protein modification processGO:00064644380.034
regulation of intracellular signal transductionGO:19025312360.034
wing disc morphogenesisGO:00074723440.034
response to biotic stimulusGO:00096072940.034
matingGO:00076181200.034
positive regulation of rna biosynthetic processGO:19026802660.034
organonitrogen compound metabolic processGO:19015643180.033
positive regulation of cell communicationGO:00106472500.033
positive regulation of intracellular signal transductionGO:19025331160.032
regulation of molecular functionGO:00650092170.032
appendage developmentGO:00487364010.032
transmembrane transportGO:00550851390.031
regulation of neuron differentiationGO:00456641030.031
positive regulation of biosynthetic processGO:00098913160.031
small molecule metabolic processGO:00442813050.031
cell deathGO:00082192790.030
centrosome cycleGO:00070981370.030
positive regulation of macromolecule metabolic processGO:00106044050.030
cellular amino acid metabolic processGO:0006520610.029
defense responseGO:00069523000.029
cellular amine metabolic processGO:0044106120.029
benzene containing compound metabolic processGO:004253730.028
response to bacteriumGO:00096171980.028
response to organic substanceGO:00100332840.028
single organism cellular localizationGO:19025801800.028
positive regulation of signalingGO:00230562430.028
single organism intracellular transportGO:19025822070.027
transcription from rna polymerase ii promoterGO:00063663680.027
gland developmentGO:00487321910.027
dendrite developmentGO:00163582040.027
synaptic transmissionGO:00072682880.026
ion transportGO:00068111450.026
g protein coupled receptor signaling pathwayGO:00071861360.026
cation transportGO:00068121100.026
salivary gland morphogenesisGO:00074351450.026
immune system processGO:00023763470.025
microtubule organizing center organizationGO:00310231680.025
regulation of catalytic activityGO:00507901850.025
cellular ketone metabolic processGO:0042180240.025
positive regulation of phosphate metabolic processGO:00459371390.025
reproductive behaviorGO:00190981220.025
regionalizationGO:00030024160.024
positive regulation of rna metabolic processGO:00512542710.024
negative regulation of response to stimulusGO:00485852580.024
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.024
post embryonic appendage morphogenesisGO:00351203850.024
intracellular transportGO:00469072280.023
regulation of protein metabolic processGO:00512462560.023
positive regulation of macromolecule biosynthetic processGO:00105572830.023
regulation of phosphate metabolic processGO:00192202100.023
amine metabolic processGO:0009308120.023
gene silencingGO:00164581380.023
organic substance transportGO:00717022570.023
eye developmentGO:00016543230.023
nuclear divisionGO:00002803320.022
negative regulation of signalingGO:00230572190.022
positive regulation of cellular biosynthetic processGO:00313283160.022
proteolysisGO:00065081920.022
epithelial cell differentiationGO:00308553220.022
centrosome organizationGO:00512971630.022
regulation of catabolic processGO:00098941700.022
embryonic development via the syncytial blastodermGO:00017001480.022
response to abiotic stimulusGO:00096283410.022
positive regulation of nucleic acid templated transcriptionGO:19035082660.022
regulation of cellular amine metabolic processGO:003323830.021
defense response to bacteriumGO:00427421780.021
regulation of cellular amino acid metabolic processGO:000652100.021
immune responseGO:00069552460.021
positive regulation of transportGO:0051050920.021
regulation of cellular protein metabolic processGO:00322682430.021
catabolic processGO:00090564090.021
regulation of cellular ketone metabolic processGO:001056530.021
forebrain developmentGO:003090020.021
defense response to other organismGO:00985422250.020
cell cell signaling involved in cell fate commitmentGO:00451682100.020
positive regulation of phosphorus metabolic processGO:00105621390.020
response to other organismGO:00517072930.020
establishment of protein localizationGO:00451841630.020
cellular macromolecule localizationGO:00707272200.020
programmed cell deathGO:00125012570.020
regulation of gene expression epigeneticGO:00400291280.020
phosphorylationGO:00163102940.019
regulation of phosphorus metabolic processGO:00511742100.019
synapse assemblyGO:00074161430.019
l amino acid importGO:004309220.019
camera type eye developmentGO:004301040.019
developmental maturationGO:00217001720.019
negative regulation of gene expressionGO:00106293870.019
positive regulation of transcription dna templatedGO:00458932660.019
chromosome organizationGO:00512763600.019
tissue deathGO:00162711020.019
protein localizationGO:00081042840.019
chemosensory behaviorGO:00076351060.019
regulation of ion transportGO:0043269390.019
histolysisGO:00075591020.019
response to oxygen containing compoundGO:19017002000.019
negative regulation of cellular metabolic processGO:00313243820.019
sensory perception of painGO:001923340.019
positive regulation of catalytic activityGO:00430851180.018
positive regulation of phosphorylationGO:0042327870.018
organelle fissionGO:00482853400.018
centrosome duplicationGO:00512981210.018
organic substance catabolic processGO:19015753080.018
olfactory behaviorGO:0042048970.018
regulation of cell deathGO:00109411730.018
negative regulation of nitrogen compound metabolic processGO:00511722650.018
positive regulation of cellular amine metabolic processGO:003324000.018
axonogenesisGO:00074092900.018
negative regulation of cell communicationGO:00106482230.017
compound eye developmentGO:00487493070.017
lateral inhibitionGO:00463312060.017
regulation of phosphorylationGO:00423251470.017
epithelial cell developmentGO:00020642740.017
locomotory behaviorGO:00076261760.017
organophosphate metabolic processGO:00196371950.017
regulation of small gtpase mediated signal transductionGO:0051056930.017
synapse organizationGO:00508081960.017
salivary gland cell autophagic cell deathGO:0035071830.017
ras protein signal transductionGO:0007265880.017
regulation of organelle organizationGO:00330431960.017
male gamete generationGO:00482322010.017
endomembrane system organizationGO:00102561190.017
regulation of response to stressGO:00801342000.017
regulation of vesicle mediated transportGO:0060627590.017
synaptic target recognitionGO:0008039450.017
dorsal ventral pattern formationGO:00099531330.017
multi organism behaviorGO:00517051750.017
body morphogenesisGO:001017120.016
chromatin organizationGO:00063252070.016
tube developmentGO:00352952440.016
positive regulation of gene expressionGO:00106282900.016
carbohydrate derivative metabolic processGO:19011352170.016
regulation of neuron projection developmentGO:0010975690.016
sterol homeostasisGO:005509240.016
regulation of multicellular organismal developmentGO:20000264140.016
posttranscriptional regulation of gene expressionGO:00106081450.016
single organism catabolic processGO:00447122280.016
photoreceptor cell differentiationGO:00465301700.016
developmental pigmentationGO:0048066680.016
salivary gland developmentGO:00074311620.015
positive regulation of protein metabolic processGO:00512471280.015
kidney developmentGO:000182230.015
ion transmembrane transportGO:00342201220.015
carbohydrate metabolic processGO:0005975820.015
regulation of dendrite developmentGO:0050773370.015
inter male aggressive behaviorGO:0002121600.015
positive regulation of cellular amino acid metabolic processGO:004576400.015
regulation of cell developmentGO:00602842150.015
positive regulation of neurogenesisGO:0050769410.015
central nervous system developmentGO:00074172010.015
cholesterol homeostasisGO:004263230.015
purine nucleotide metabolic processGO:00061631460.015
sensory perceptionGO:00076001960.015
single organism biosynthetic processGO:00447112060.015
salivary gland histolysisGO:0035070880.015
dendrite morphogenesisGO:00488131990.015
regulation of cell differentiationGO:00455953020.015
autophagic cell deathGO:0048102830.015
exocrine system developmentGO:00352721620.015
regulation of transcription from rna polymerase ii promoterGO:00063573780.015
single organism carbohydrate metabolic processGO:0044723720.015
columnar cuboidal epithelial cell developmentGO:00020662490.015
positive regulation of developmental processGO:00510941430.015
cellular response to ethanolGO:007136140.014
spermatogenesisGO:00072832000.014
neuropeptide signaling pathwayGO:0007218450.014
positive regulation of mapk cascadeGO:0043410630.014
meiotic cell cycleGO:00513211710.014
regulation of ras protein signal transductionGO:0046578930.014
organelle localizationGO:00516401480.014
enzyme linked receptor protein signaling pathwayGO:00071671790.014
regulation of gene silencingGO:0060968630.014
cellular catabolic processGO:00442483720.014
regulation of apoptotic processGO:00429811300.013
negative regulation of cellular component organizationGO:00511291080.013
ribonucleotide metabolic processGO:00092591450.013
single organism membrane organizationGO:0044802930.013
regulation of synaptic transmissionGO:0050804690.013
cellular response to chemical stimulusGO:00708871990.013
membrane organizationGO:00610241120.013
inorganic ion transmembrane transportGO:0098660730.013
regulation of synapse structure and activityGO:00508031280.013
response to lipopolysaccharideGO:003249640.013
regulation of immune system processGO:00026821760.013
negative regulation of biosynthetic processGO:00098902770.013
eggshell formationGO:00307031050.013
positive regulation of exocytosisGO:004592140.013
cellularizationGO:0007349900.013
regulation of membrane potentialGO:0042391350.013
protein modification by small protein conjugation or removalGO:00706471060.013
response to copper ionGO:004668840.013
response to woundingGO:0009611940.013
detection of light stimulusGO:0009583580.013
positive regulation of calcium ion transportGO:005192840.013
negative regulation of rna metabolic processGO:00512532510.013
pigment metabolic processGO:0042440840.013
regulation of cellular catabolic processGO:00313291570.013
regulation of transferase activityGO:0051338580.013
heterocycle catabolic processGO:00467001660.013
synaptic vesicle transportGO:0048489500.013
dorsal ventral axis specificationGO:0009950660.013
signal transduction by phosphorylationGO:00230141070.013
compound eye photoreceptor cell differentiationGO:00017511400.013
protein phosphorylationGO:00064681690.013
adult locomotory behaviorGO:0008344760.012
dna metabolic processGO:00062592270.012
response to endogenous stimulusGO:00097191190.012
eye photoreceptor cell developmentGO:0042462810.012
positive regulation of cell deathGO:0010942690.012
cell maturationGO:00484691440.012
regulation of protein modification processGO:00313991120.012
negative regulation of signal transductionGO:00099682060.012
cellular macromolecule catabolic processGO:00442651360.012
protein processingGO:0016485680.012
positive regulation of erk1 and erk2 cascadeGO:0070374360.012
detection of stimulusGO:00516061560.012
positive regulation of molecular functionGO:00440931360.012
lipid metabolic processGO:00066291210.012
tissue morphogenesisGO:00487292970.012
positive regulation of catabolic processGO:00098961050.012
regulation of cell cycle phase transitionGO:19019871300.012
developmental programmed cell deathGO:00106231380.012
tube morphogenesisGO:00352391910.012
cellular modified amino acid metabolic processGO:0006575450.012
ovarian follicle cell developmentGO:00307072480.012
intracellular protein transportGO:00068861040.012
mapk cascadeGO:00001651070.012
cellular protein localizationGO:00346131600.012
mitotic spindle organizationGO:00070522200.012
regulation of programmed cell deathGO:00430671520.011
chemical homeostasisGO:0048878920.011
telencephalon developmentGO:002153720.011
secretion by cellGO:00329401010.011
regulation of nervous system developmentGO:00519602480.011
establishment of organelle localizationGO:00516561220.011
negative regulation of cell differentiationGO:00455961430.011
regulation of sterol transportGO:003237110.011
positive regulation of cellular protein metabolic processGO:00322701180.011
androgen metabolic processGO:000820910.011
gtp catabolic processGO:0006184720.011
positive regulation of hydrolase activityGO:0051345780.011
compound eye morphogenesisGO:00017452490.011
purine ribonucleotide metabolic processGO:00091501450.011
cellular response to organic substanceGO:00713101320.011
rna localizationGO:00064031150.011
secondary metabolic processGO:0019748750.011
phosphatidylethanolamine metabolic processGO:004633710.011
cholesterol transportGO:003030120.011
organophosphate catabolic processGO:00464341120.011
homeostatic processGO:00425921990.011
regulation of gtpase activityGO:0043087440.011
apoptotic processGO:00069151590.011
xenobiotic catabolic processGO:004217810.011
digestive system developmentGO:00551231490.011
ribosomal large subunit biogenesisGO:004227310.011
protein ubiquitinationGO:0016567700.011
digestive tract developmentGO:00485651490.011
nucleobase containing small molecule metabolic processGO:00550861740.011
synaptic vesicle localizationGO:0097479530.011
response to nitrogen compoundGO:1901698900.011
response to radiationGO:00093141550.011
phototransductionGO:0007602520.011
secretionGO:00469031090.011
regulation of mapk cascadeGO:0043408920.011
cell proliferationGO:00082832990.011
kidney epithelium developmentGO:007207330.011
taxisGO:00423303040.011
protein transportGO:00150311550.011
regulation of synapse organizationGO:00508071100.011
protein modification by small protein conjugationGO:0032446790.011
anatomical structure homeostasisGO:0060249970.010
spermatid differentiationGO:00485151140.010
modification dependent protein catabolic processGO:0019941780.010
respiratory system developmentGO:00605412130.010
dna conformation changeGO:00711031050.010
sulfur compound metabolic processGO:0006790590.010
anterior posterior pattern specificationGO:00099521360.010
negative regulation of protein metabolic processGO:0051248850.010
oocyte constructionGO:00073081120.010
regulation of erk1 and erk2 cascadeGO:0070372390.010
negative regulation of transcription dna templatedGO:00458922370.010
ribonucleoside triphosphate metabolic processGO:00091991190.010
columnar cuboidal epithelial cell differentiationGO:00020652560.010
regulation of lipid transportGO:003236830.010
response to glucoseGO:000974920.010
nucleotide metabolic processGO:00091171610.010
regulation of mitotic cell cycleGO:00073461900.010

Pde9 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.047
nervous system diseaseDOID:86300.023
inherited metabolic disorderDOID:65500.019
familial hyperlipidemiaDOID:116800.019
lipid metabolism disorderDOID:314600.019
disease of metabolismDOID:001466700.019
sensory system diseaseDOID:005015500.014
eye diseaseDOID:561400.013
eye and adnexa diseaseDOID:149200.013