IMP: Integrative Multi-species Prediction

Drosophila melanogaster

21 known processes

RpL39 (Dmel_CG3997)

Ribosomal protein L39

(Aliases: Rp46,rp46,BcDNA:RH27094,anon-EST:Posey16,M(2)60B,Dmel\CG3997,RpL46,RPl46,CG3997,L39)

Entrez: 37849
FLYBASE: FBgn0023170
UniProtKB: O16130

Process Predictions
Disease Predictions

RpL39 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
mitotic spindle organization	GO:0007052	220	0.313
mitotic spindle elongation	GO:0000022	81	0.203
regulation of growth	GO:0040008	233	0.189	Worm
death	GO:0016265	284	0.173	Worm
response to other organism	GO:0051707	293	0.150	Human
organic substance transport	GO:0071702	257	0.136
centrosome organization	GO:0051297	163	0.129
response to biotic stimulus	GO:0009607	294	0.109	Human
developmental growth	GO:0048589	280	0.109	Worm
cell migration	GO:0016477	238	0.107
homeostatic process	GO:0042592	199	0.102
single organism intracellular transport	GO:1902582	207	0.095
protein modification process	GO:0036211	438	0.092
positive regulation of rna metabolic process	GO:0051254	271	0.092
defense response	GO:0006952	300	0.089	Human
intracellular transport	GO:0046907	228	0.087
negative regulation of rna metabolic process	GO:0051253	251	0.087
positive regulation of gene expression	GO:0010628	290	0.082
regulation of cell cycle g1 s phase transition	GO:1902806	23	0.077
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.075
regulation of cell cycle	GO:0051726	291	0.073
cell cycle g1 s phase transition	GO:0044843	31	0.071
positive regulation of developmental process	GO:0051094	143	0.069	Worm
localization of cell	GO:0051674	257	0.068
response to abiotic stimulus	GO:0009628	341	0.067
regulation of catabolic process	GO:0009894	170	0.066
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.065
positive regulation of cellular catabolic process	GO:0031331	95	0.064
apoptotic process	GO:0006915	159	0.062	Worm
brain development	GO:0007420	120	0.062
negative regulation of cellular metabolic process	GO:0031324	382	0.061
centrosome duplication	GO:0051298	121	0.060
regulation of cell cycle process	GO:0010564	181	0.060
head development	GO:0060322	135	0.060
cell cycle phase transition	GO:0044770	140	0.058
multicellular organismal aging	GO:0010259	140	0.057
nucleocytoplasmic transport	GO:0006913	72	0.055
regulation of multicellular organism growth	GO:0040014	40	0.054	Worm
molting cycle	GO:0042303	56	0.053
positive regulation of multicellular organismal process	GO:0051240	143	0.051	Worm
catabolic process	GO:0009056	409	0.050
embryo development ending in birth or egg hatching	GO:0009792	152	0.050	Worm
regulation of g1 s transition of mitotic cell cycle	GO:2000045	23	0.049
negative regulation of gene expression	GO:0010629	387	0.049
programmed cell death	GO:0012501	257	0.048	Worm
aging	GO:0007568	143	0.048
nuclear export	GO:0051168	24	0.047
cytoplasmic transport	GO:0016482	130	0.046
positive regulation of catabolic process	GO:0009896	105	0.046
response to bacterium	GO:0009617	198	0.046	Human
cell motility	GO:0048870	251	0.045
regulation of developmental growth	GO:0048638	174	0.045	Worm
nuclear transport	GO:0051169	72	0.045
organic substance catabolic process	GO:1901575	308	0.044
central nervous system development	GO:0007417	201	0.044
negative regulation of cellular biosynthetic process	GO:0031327	277	0.043
cell death	GO:0008219	279	0.043	Worm
response to external biotic stimulus	GO:0043207	293	0.043	Human
larval development	GO:0002164	104	0.043	Worm
small molecule metabolic process	GO:0044281	305	0.043
regulation of molecular function	GO:0065009	217	0.042
reproductive system development	GO:0061458	74	0.041
regulation of mitotic cell cycle	GO:0007346	190	0.041
establishment of localization in cell	GO:0051649	402	0.040
regulation of cellular catabolic process	GO:0031329	157	0.039
response to organic substance	GO:0010033	284	0.038
protein catabolic process	GO:0030163	101	0.038
cellular response to dna damage stimulus	GO:0006974	223	0.038
determination of adult lifespan	GO:0008340	137	0.038
endocytosis	GO:0006897	310	0.037
centrosome cycle	GO:0007098	137	0.036
cellular protein modification process	GO:0006464	438	0.036
transmembrane transport	GO:0055085	139	0.036
ribonucleoprotein complex assembly	GO:0022618	23	0.036
growth	GO:0040007	359	0.036	Worm
posttranscriptional regulation of gene expression	GO:0010608	145	0.035
spindle organization	GO:0007051	253	0.035
phagocytosis	GO:0006909	215	0.035
positive regulation of cellular biosynthetic process	GO:0031328	316	0.034
negative regulation of biosynthetic process	GO:0009890	277	0.034
positive regulation of response to stimulus	GO:0048584	323	0.033
regulation of catalytic activity	GO:0050790	185	0.033
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.033
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.033
regulation of cell cycle phase transition	GO:1901987	130	0.033
body morphogenesis	GO:0010171	2	0.033
protein transport	GO:0015031	155	0.030
positive regulation of programmed cell death	GO:0043068	62	0.030
mitotic cell cycle phase transition	GO:0044772	138	0.029
cellular catabolic process	GO:0044248	372	0.029
negative regulation of cell cycle	GO:0045786	116	0.029
chemical homeostasis	GO:0048878	92	0.029
organelle assembly	GO:0070925	198	0.028
mitotic dna damage checkpoint	GO:0044773	74	0.028
zymogen activation	GO:0031638	20	0.028
positive regulation of macromolecule metabolic process	GO:0010604	405	0.027
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.027
regulation of cell death	GO:0010941	173	0.026
positive regulation of proteolysis	GO:0045862	52	0.026
protein localization	GO:0008104	284	0.026
regulation of protein metabolic process	GO:0051246	256	0.026
heterocycle catabolic process	GO:0046700	166	0.025
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.025
nitrogen compound transport	GO:0071705	85	0.024
gene silencing	GO:0016458	138	0.024
chromatin organization	GO:0006325	207	0.024
memory	GO:0007613	94	0.024
carboxylic acid metabolic process	GO:0019752	92	0.024
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.024
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.024
negative regulation of response to stimulus	GO:0048585	258	0.023
organic cyclic compound catabolic process	GO:1901361	168	0.023
chromosome organization	GO:0051276	360	0.023
development of primary sexual characteristics	GO:0045137	50	0.022
ion transmembrane transport	GO:0034220	122	0.022
regulation of response to stress	GO:0080134	200	0.022
cellular response to organic substance	GO:0071310	132	0.021
positive regulation of catalytic activity	GO:0043085	118	0.021
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.021
positive regulation of biosynthetic process	GO:0009891	316	0.021
regulation of cellular protein metabolic process	GO:0032268	243	0.021
positive regulation of mrna catabolic process	GO:0061014	5	0.021
compound eye development	GO:0048749	307	0.021
inorganic ion transmembrane transport	GO:0098660	73	0.020
regulation of programmed cell death	GO:0043067	152	0.020
sex differentiation	GO:0007548	81	0.020
innate immune response	GO:0045087	144	0.020	Human
cellular nitrogen compound catabolic process	GO:0044270	165	0.020
cellular response to chemical stimulus	GO:0070887	199	0.020
mitotic cell cycle checkpoint	GO:0007093	88	0.020
intracellular protein transport	GO:0006886	104	0.020
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.020
regulation of localization	GO:0032879	275	0.020
regulation of proteolysis	GO:0030162	87	0.020
gonad development	GO:0008406	50	0.020
activation of cysteine type endopeptidase activity	GO:0097202	17	0.019
negative regulation of cell cycle process	GO:0010948	109	0.019
vesicle mediated transport	GO:0016192	381	0.019
organonitrogen compound catabolic process	GO:1901565	128	0.019
spindle elongation	GO:0051231	83	0.019
nucleobase containing compound catabolic process	GO:0034655	165	0.019
nucleotide metabolic process	GO:0009117	161	0.018
regulation of apoptotic process	GO:0042981	130	0.018
negative regulation of rna biosynthetic process	GO:1902679	240	0.018
lipid metabolic process	GO:0006629	121	0.018
organonitrogen compound metabolic process	GO:1901564	318	0.018
defense response to other organism	GO:0098542	225	0.018	Human
chromatin modification	GO:0016568	147	0.018
nucleobase containing small molecule metabolic process	GO:0055086	174	0.018
cation transmembrane transport	GO:0098655	88	0.017
response to endogenous stimulus	GO:0009719	119	0.017
positive regulation of molecular function	GO:0044093	136	0.017
establishment of protein localization	GO:0045184	163	0.017
actin mediated cell contraction	GO:0070252	21	0.017
immune system process	GO:0002376	347	0.017	Human
cell cycle checkpoint	GO:0000075	95	0.017
rna processing	GO:0006396	147	0.017
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.017
glycosyl compound metabolic process	GO:1901657	127	0.016
positive regulation of cell communication	GO:0010647	250	0.016
ncrna metabolic process	GO:0034660	43	0.016
macromolecule catabolic process	GO:0009057	161	0.016
organic acid metabolic process	GO:0006082	103	0.016
response to oxygen containing compound	GO:1901700	200	0.016
secretion	GO:0046903	109	0.016
proteolysis	GO:0006508	192	0.015
cellular response to oxygen containing compound	GO:1901701	79	0.015
regulation of immune response	GO:0050776	118	0.015
reproductive structure development	GO:0048608	74	0.015
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.015
response to organonitrogen compound	GO:0010243	75	0.015
rrna processing	GO:0006364	3	0.015
dna metabolic process	GO:0006259	227	0.015
protein complex biogenesis	GO:0070271	201	0.014
organophosphate metabolic process	GO:0019637	195	0.014
epithelium migration	GO:0090132	148	0.014
dna damage checkpoint	GO:0000077	78	0.014
single organism catabolic process	GO:0044712	228	0.014
positive regulation of signal transduction	GO:0009967	223	0.014
rna localization	GO:0006403	115	0.014
mrna metabolic process	GO:0016071	124	0.013
eye morphogenesis	GO:0048592	260	0.013
ion transport	GO:0006811	145	0.013
secretion by cell	GO:0032940	101	0.013
response to radiation	GO:0009314	155	0.013
aromatic compound catabolic process	GO:0019439	166	0.013
regulation of cell proliferation	GO:0042127	163	0.013
cation transport	GO:0006812	110	0.013
positive regulation of apoptotic process	GO:0043065	47	0.013
lipid storage	GO:0019915	38	0.013
antimicrobial humoral response	GO:0019730	99	0.012	Human
eye development	GO:0001654	323	0.012
response to wounding	GO:0009611	94	0.012
regulation of transport	GO:0051049	181	0.012
negative regulation of cell cycle phase transition	GO:1901988	103	0.012
carbohydrate derivative metabolic process	GO:1901135	217	0.012
salivary gland morphogenesis	GO:0007435	145	0.012
response to nitrogen compound	GO:1901698	90	0.012
establishment of organelle localization	GO:0051656	122	0.012
negative regulation of cell communication	GO:0010648	223	0.012
maintenance of location	GO:0051235	73	0.012
dna integrity checkpoint	GO:0031570	81	0.011
positive regulation of growth	GO:0045927	75	0.011	Worm
regulation of defense response	GO:0031347	102	0.011
regulation of peptidase activity	GO:0052547	39	0.011
multicellular organism growth	GO:0035264	46	0.011	Worm
g1 s transition of mitotic cell cycle	GO:0000082	31	0.011
protein targeting	GO:0006605	64	0.011
mrna catabolic process	GO:0006402	33	0.011
purine containing compound metabolic process	GO:0072521	155	0.011
activation of cysteine type endopeptidase activity involved in apoptotic process	GO:0006919	16	0.011
behavioral response to ethanol	GO:0048149	49	0.011
single organism behavior	GO:0044708	391	0.011
regulation of cellular localization	GO:0060341	136	0.011
positive regulation of mrna metabolic process	GO:1903313	5	0.011
lipid localization	GO:0010876	54	0.011
positive regulation of signaling	GO:0023056	243	0.011
positive regulation of intracellular signal transduction	GO:1902533	116	0.011
photoreceptor cell differentiation	GO:0046530	170	0.011
positive regulation of cell death	GO:0010942	69	0.011
appendage development	GO:0048736	401	0.011
transcription from rna polymerase ii promoter	GO:0006366	368	0.011
cell growth	GO:0016049	108	0.011
positive regulation of protein metabolic process	GO:0051247	128	0.011
cellular response to endogenous stimulus	GO:0071495	80	0.011
microtubule organizing center organization	GO:0031023	168	0.010
regulation of gene expression epigenetic	GO:0040029	128	0.010
cellular protein localization	GO:0034613	160	0.010
wing disc morphogenesis	GO:0007472	344	0.010
nucleoside phosphate metabolic process	GO:0006753	162	0.010
protein modification by small protein conjugation or removal	GO:0070647	106	0.010
rna transport	GO:0050658	46	0.010
nuclear transcribed mrna catabolic process	GO:0000956	24	0.010
protein modification by small protein conjugation	GO:0032446	79	0.010
regulation of multicellular organismal development	GO:2000026	414	0.010
regulation of response to external stimulus	GO:0032101	115	0.010

RpL39 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.024

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