IMP: Integrative Multi-species Prediction

Drosophila melanogaster

29 known processes

CG16974 (Dmel_CG16974)

CG16974 gene product from transcript CG16974-RA

(Aliases: CT35580,Dmel\CG16974,Dromel_CG16974_FBtr0080489_mORF)

Entrez: 34713
FLYBASE: FBgn0032479
UniProtKB: Q9VK28

Process Predictions
Disease Predictions

CG16974 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
lateral inhibition	GO:0046331	206	0.124
synapse organization	GO:0050808	196	0.072
spermatogenesis	GO:0007283	200	0.071
small molecule metabolic process	GO:0044281	305	0.049
catabolic process	GO:0009056	409	0.048
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.047
regulation of multicellular organismal development	GO:2000026	414	0.046
nucleobase containing compound catabolic process	GO:0034655	165	0.044
endocytosis	GO:0006897	310	0.042
organic substance catabolic process	GO:1901575	308	0.041
mrna metabolic process	GO:0016071	124	0.040
purine containing compound catabolic process	GO:0072523	112	0.038
organic cyclic compound catabolic process	GO:1901361	168	0.037
cell cell adhesion via plasma membrane adhesion molecules	GO:0098742	26	0.037
positive regulation of gtpase activity	GO:0043547	43	0.036
death	GO:0016265	284	0.035
cellular nitrogen compound catabolic process	GO:0044270	165	0.033
male gamete generation	GO:0048232	201	0.032
heterocycle catabolic process	GO:0046700	166	0.032
cellular protein modification process	GO:0006464	438	0.031
programmed cell death	GO:0012501	257	0.031
alternative mrna splicing via spliceosome	GO:0000380	60	0.031
protein modification by small protein conjugation	GO:0032446	79	0.030
cellularization	GO:0007349	90	0.030
vesicle mediated transport	GO:0016192	381	0.029
positive regulation of response to stimulus	GO:0048584	323	0.029
head development	GO:0060322	135	0.028
organonitrogen compound metabolic process	GO:1901564	318	0.027
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.027
embryonic pattern specification	GO:0009880	174	0.026
transmembrane transport	GO:0055085	139	0.026
purine ribonucleotide metabolic process	GO:0009150	145	0.026
aromatic compound catabolic process	GO:0019439	166	0.026
regulation of mrna metabolic process	GO:1903311	72	0.026
posttranscriptional regulation of gene expression	GO:0010608	145	0.025
rna splicing via transesterification reactions	GO:0000375	73	0.025
compound eye development	GO:0048749	307	0.024	Fly
adult behavior	GO:0030534	137	0.024
spermatid differentiation	GO:0048515	114	0.023
regulation of nervous system development	GO:0051960	248	0.022
anterior posterior pattern specification	GO:0009952	136	0.022
cell cell adhesion	GO:0098609	26	0.022
protein ubiquitination	GO:0016567	70	0.022
regulation of multi organism process	GO:0043900	131	0.021
carboxylic acid metabolic process	GO:0019752	92	0.021
regulation of phosphorus metabolic process	GO:0051174	210	0.020
positive regulation of phosphate metabolic process	GO:0045937	139	0.020
ribonucleoside catabolic process	GO:0042454	112	0.020
cell proliferation	GO:0008283	299	0.020
cellular catabolic process	GO:0044248	372	0.020
single organism catabolic process	GO:0044712	228	0.019
carbohydrate derivative metabolic process	GO:1901135	217	0.019
regulation of cell differentiation	GO:0045595	302	0.019
regulation of protein metabolic process	GO:0051246	256	0.019
actin filament based process	GO:0030029	220	0.019
negative regulation of developmental process	GO:0051093	201	0.019
regulation of phosphate metabolic process	GO:0019220	210	0.019
cell recognition	GO:0008037	102	0.019
protein modification process	GO:0036211	438	0.019
single organism behavior	GO:0044708	391	0.019
mrna processing	GO:0006397	104	0.018
segmentation	GO:0035282	207	0.018
tripartite regional subdivision	GO:0007351	103	0.018
apoptotic process	GO:0006915	159	0.018
regulation of molecular function	GO:0065009	217	0.017
regulation of catalytic activity	GO:0050790	185	0.017
regulation of cell development	GO:0060284	215	0.017
cell death	GO:0008219	279	0.017
biological adhesion	GO:0022610	138	0.017
positive regulation of cellular component organization	GO:0051130	156	0.017
purine ribonucleoside metabolic process	GO:0046128	127	0.017
nucleoside metabolic process	GO:0009116	127	0.017
regulation of alternative mrna splicing via spliceosome	GO:0000381	60	0.016
brain development	GO:0007420	120	0.016
ribonucleotide catabolic process	GO:0009261	109	0.016
regulation of hydrolase activity	GO:0051336	97	0.016
anterior posterior axis specification	GO:0009948	109	0.016
ribonucleoside metabolic process	GO:0009119	127	0.016
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.016
intracellular transport	GO:0046907	228	0.016
blastoderm segmentation	GO:0007350	159	0.016
positive regulation of hydrolase activity	GO:0051345	78	0.016
nucleotide catabolic process	GO:0009166	109	0.016
positive regulation of purine nucleotide metabolic process	GO:1900544	55	0.016
growth	GO:0040007	359	0.015
response to abiotic stimulus	GO:0009628	341	0.015
cellular macromolecule catabolic process	GO:0044265	136	0.015
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.015
nucleoside phosphate metabolic process	GO:0006753	162	0.015
purine nucleoside metabolic process	GO:0042278	127	0.015
body morphogenesis	GO:0010171	2	0.015
regulation of purine nucleotide catabolic process	GO:0033121	48	0.015
phagocytosis	GO:0006909	215	0.015
positive regulation of catabolic process	GO:0009896	105	0.014
neuron recognition	GO:0008038	101	0.014
o glycan processing	GO:0016266	3	0.014
nucleoside catabolic process	GO:0009164	112	0.014
protein modification by small protein conjugation or removal	GO:0070647	106	0.014
regulation of synapse organization	GO:0050807	110	0.014
actin cytoskeleton organization	GO:0030036	206	0.014
regionalization	GO:0003002	416	0.014
regulation of gtp catabolic process	GO:0033124	44	0.014
maternal determination of anterior posterior axis embryo	GO:0008358	74	0.014
negative regulation of multicellular organismal process	GO:0051241	142	0.013
spermatid development	GO:0007286	98	0.013
rna splicing via transesterification reactions with bulged adenosine as nucleophile	GO:0000377	73	0.013
phosphorylation	GO:0016310	294	0.013
positive regulation of nucleotide metabolic process	GO:0045981	55	0.013
nucleoside phosphate catabolic process	GO:1901292	110	0.013
mrna splicing via spliceosome	GO:0000398	73	0.013
eye morphogenesis	GO:0048592	260	0.013
organophosphate metabolic process	GO:0019637	195	0.013
respiratory system development	GO:0060541	213	0.013
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.013
ribonucleoside monophosphate metabolic process	GO:0009161	51	0.013
negative regulation of cell differentiation	GO:0045596	143	0.013
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.012
single organism intracellular transport	GO:1902582	207	0.012
nucleotide metabolic process	GO:0009117	161	0.012
organonitrogen compound catabolic process	GO:1901565	128	0.012
positive regulation of developmental process	GO:0051094	143	0.012
purine nucleoside catabolic process	GO:0006152	112	0.012
wing disc morphogenesis	GO:0007472	344	0.012
digestive system development	GO:0055123	149	0.012
ribonucleoside monophosphate catabolic process	GO:0009158	39	0.012
regulation of mrna splicing via spliceosome	GO:0048024	64	0.012
adult locomotory behavior	GO:0008344	76	0.012
regulation of cellular ketone metabolic process	GO:0010565	3	0.012
purine nucleotide metabolic process	GO:0006163	146	0.012
mesenchymal cell development	GO:0014031	1	0.012
central nervous system development	GO:0007417	201	0.011
nucleoside triphosphate catabolic process	GO:0009143	108	0.011
regulation of response to stress	GO:0080134	200	0.011
organic substance transport	GO:0071702	257	0.011
purine containing compound metabolic process	GO:0072521	155	0.011
glycosyl compound metabolic process	GO:1901657	127	0.011
regulation of axonogenesis	GO:0050770	32	0.011
forebrain development	GO:0030900	2	0.011
aging	GO:0007568	143	0.011
embryonic axis specification	GO:0000578	107	0.011
positive regulation of cellular catabolic process	GO:0031331	95	0.011
cell migration	GO:0016477	238	0.011
regulation of localization	GO:0032879	275	0.011
sperm individualization	GO:0007291	48	0.011
purine ribonucleotide catabolic process	GO:0009154	109	0.011
regulation of cell proliferation	GO:0042127	163	0.011
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.010
dna repair	GO:0006281	54	0.010
regulation of transport	GO:0051049	181	0.010
macromolecule catabolic process	GO:0009057	161	0.010
establishment or maintenance of cell polarity	GO:0007163	167	0.010
positive regulation of catalytic activity	GO:0043085	118	0.010
organophosphate catabolic process	GO:0046434	112	0.010

CG16974 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.012
nervous system disease	DOID:863	0.012
neurodegenerative disease	DOID:1289	0.012
central nervous system disease	DOID:331	0.012

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