| negative regulation of response to stimulus | GO:0048585 | 258 | 0.602 | |
| stem cell development | GO:0048864 | 79 | 0.597 | |
| negative regulation of signaling | GO:0023057 | 219 | 0.595 | |
| cellular response to chemical stimulus | GO:0070887 | 199 | 0.578 | |
| stem cell differentiation | GO:0048863 | 117 | 0.569 | |
| cellular response to organic substance | GO:0071310 | 132 | 0.509 | |
| negative regulation of signal transduction | GO:0009968 | 206 | 0.456 | |
| negative regulation of cell communication | GO:0010648 | 223 | 0.452 | |
| transcription from rna polymerase ii promoter | GO:0006366 | 368 | 0.428 | Fly |
| dna damage checkpoint | GO:0000077 | 78 | 0.328 | |
| mitotic dna integrity checkpoint | GO:0044774 | 75 | 0.300 | |
| negative regulation of developmental process | GO:0051093 | 201 | 0.291 | Worm |
| rna processing | GO:0006396 | 147 | 0.289 | |
| enzyme linked receptor protein signaling pathway | GO:0007167 | 179 | 0.282 | |
| mrna metabolic process | GO:0016071 | 124 | 0.278 | |
| spindle organization | GO:0007051 | 253 | 0.269 | |
| regulation of response to stress | GO:0080134 | 200 | 0.256 | |
| cell cycle phase transition | GO:0044770 | 140 | 0.232 | |
| negative regulation of cell cycle phase transition | GO:1901988 | 103 | 0.209 | |
| regulation of cell differentiation | GO:0045595 | 302 | 0.202 | |
| determination of adult lifespan | GO:0008340 | 137 | 0.197 | |
| response to oxygen containing compound | GO:1901700 | 200 | 0.193 | |
| regulation of immune system process | GO:0002682 | 176 | 0.188 | |
| proteolysis | GO:0006508 | 192 | 0.165 | |
| response to organic substance | GO:0010033 | 284 | 0.154 | |
| negative regulation of macromolecule biosynthetic process | GO:0010558 | 270 | 0.143 | |
| positive regulation of transcription dna templated | GO:0045893 | 266 | 0.142 | |
| dna templated transcription elongation | GO:0006354 | 18 | 0.141 | |
| cell division | GO:0051301 | 248 | 0.140 | |
| positive regulation of transcription from rna polymerase ii promoter | GO:0045944 | 204 | 0.131 | |
| regulation of immune response | GO:0050776 | 118 | 0.128 | |
| immune response | GO:0006955 | 246 | 0.127 | |
| regulation of mitotic cell cycle | GO:0007346 | 190 | 0.124 | Fly |
| immune system process | GO:0002376 | 347 | 0.122 | |
| positive regulation of macromolecule biosynthetic process | GO:0010557 | 283 | 0.119 | |
| negative regulation of cellular metabolic process | GO:0031324 | 382 | 0.106 | |
| positive regulation of neuron projection regeneration | GO:0070572 | 3 | 0.105 | |
| positive regulation of cellular biosynthetic process | GO:0031328 | 316 | 0.105 | |
| defense response | GO:0006952 | 300 | 0.102 | |
| regulation of transcription from rna polymerase ii promoter | GO:0006357 | 378 | 0.102 | Fly |
| response to external biotic stimulus | GO:0043207 | 293 | 0.101 | |
| regulation of cell development | GO:0060284 | 215 | 0.096 | |
| response to other organism | GO:0051707 | 293 | 0.091 | |
| multicellular organismal aging | GO:0010259 | 140 | 0.089 | |
| positive regulation of response to stimulus | GO:0048584 | 323 | 0.085 | |
| response to endogenous stimulus | GO:0009719 | 119 | 0.084 | |
| regulation of chromosome organization | GO:0033044 | 64 | 0.084 | |
| negative regulation of nucleobase containing compound metabolic process | GO:0045934 | 261 | 0.081 | |
| cell proliferation | GO:0008283 | 299 | 0.077 | Fly |
| organelle fission | GO:0048285 | 340 | 0.074 | |
| cellular response to endogenous stimulus | GO:0071495 | 80 | 0.073 | |
| catabolic process | GO:0009056 | 409 | 0.073 | |
| negative regulation of cell differentiation | GO:0045596 | 143 | 0.070 | |
| macromolecular complex assembly | GO:0065003 | 256 | 0.069 | |
| regulation of cell cycle phase transition | GO:1901987 | 130 | 0.068 | |
| positive regulation of developmental process | GO:0051094 | 143 | 0.067 | |
| response to oxidative stress | GO:0006979 | 86 | 0.067 | |
| mitotic cell cycle phase transition | GO:0044772 | 138 | 0.066 | |
| regulation of response to external stimulus | GO:0032101 | 115 | 0.063 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 130 | 0.062 | |
| defense response to other organism | GO:0098542 | 225 | 0.062 | |
| negative regulation of mitotic cell cycle phase transition | GO:1901991 | 103 | 0.062 | |
| embryo development ending in birth or egg hatching | GO:0009792 | 152 | 0.061 | Mouse Fly |
| establishment of localization in cell | GO:0051649 | 402 | 0.060 | Fly |
| eye development | GO:0001654 | 323 | 0.059 | |
| negative regulation of cell cycle process | GO:0010948 | 109 | 0.058 | |
| response to biotic stimulus | GO:0009607 | 294 | 0.058 | |
| positive regulation of biosynthetic process | GO:0009891 | 316 | 0.057 | |
| regulation of cell proliferation | GO:0042127 | 163 | 0.057 | Fly |
| protein transport | GO:0015031 | 155 | 0.057 | |
| mitotic nuclear division | GO:0007067 | 213 | 0.057 | |
| cell cycle checkpoint | GO:0000075 | 95 | 0.054 | |
| positive regulation of growth | GO:0045927 | 75 | 0.051 | |
| cellular catabolic process | GO:0044248 | 372 | 0.051 | |
| regulation of defense response | GO:0031347 | 102 | 0.051 | |
| cellular response to oxygen containing compound | GO:1901701 | 79 | 0.050 | |
| negative regulation of gene expression | GO:0010629 | 387 | 0.049 | |
| regulation of immune effector process | GO:0002697 | 52 | 0.048 | |
| sensory organ morphogenesis | GO:0090596 | 260 | 0.048 | |
| macromolecule catabolic process | GO:0009057 | 161 | 0.046 | |
| positive regulation of rna metabolic process | GO:0051254 | 271 | 0.045 | |
| response to alcohol | GO:0097305 | 95 | 0.045 | |
| locomotory behavior | GO:0007626 | 176 | 0.044 | |
| peptidyl lysine modification | GO:0018205 | 57 | 0.043 | |
| cell death | GO:0008219 | 279 | 0.043 | |
| mitotic g2 dna damage checkpoint | GO:0007095 | 69 | 0.043 | |
| cellular macromolecule catabolic process | GO:0044265 | 136 | 0.042 | |
| positive regulation of cellular component organization | GO:0051130 | 156 | 0.042 | |
| regulation of cell cycle process | GO:0010564 | 181 | 0.041 | |
| intracellular steroid hormone receptor signaling pathway | GO:0030518 | 12 | 0.041 | |
| compound eye development | GO:0048749 | 307 | 0.041 | |
| protein complex assembly | GO:0006461 | 200 | 0.040 | |
| sister chromatid segregation | GO:0000819 | 92 | 0.040 | |
| g1 s transition of mitotic cell cycle | GO:0000082 | 31 | 0.039 | |
| chemotaxis | GO:0006935 | 249 | 0.039 | |
| endocytosis | GO:0006897 | 310 | 0.039 | |
| mitotic cell cycle checkpoint | GO:0007093 | 88 | 0.039 | |
| positive regulation of developmental growth | GO:0048639 | 62 | 0.038 | |
| organic substance transport | GO:0071702 | 257 | 0.038 | |
| stem cell division | GO:0017145 | 69 | 0.037 | |
| nuclear division | GO:0000280 | 332 | 0.037 | |
| mitotic spindle organization | GO:0007052 | 220 | 0.037 | |
| establishment of protein localization | GO:0045184 | 163 | 0.037 | |
| positive regulation of cell communication | GO:0010647 | 250 | 0.036 | |
| death | GO:0016265 | 284 | 0.036 | |
| regulation of molecular function | GO:0065009 | 217 | 0.035 | |
| vesicle mediated transport | GO:0016192 | 381 | 0.034 | |
| mesenchymal cell development | GO:0014031 | 1 | 0.034 | |
| cell adhesion | GO:0007155 | 136 | 0.033 | |
| meiosis i | GO:0007127 | 59 | 0.033 | |
| central nervous system development | GO:0007417 | 201 | 0.032 | |
| response to bacterium | GO:0009617 | 198 | 0.032 | |
| covalent chromatin modification | GO:0016569 | 106 | 0.032 | |
| chromatin modification | GO:0016568 | 147 | 0.031 | |
| single organism catabolic process | GO:0044712 | 228 | 0.030 | |
| phosphorylation | GO:0016310 | 294 | 0.030 | |
| chromosome segregation | GO:0007059 | 157 | 0.030 | |
| gene silencing | GO:0016458 | 138 | 0.030 | |
| g2 dna damage checkpoint | GO:0031572 | 69 | 0.030 | |
| protein localization | GO:0008104 | 284 | 0.029 | |
| mitotic dna damage checkpoint | GO:0044773 | 74 | 0.029 | |
| organic substance catabolic process | GO:1901575 | 308 | 0.029 | |
| cellular macromolecule localization | GO:0070727 | 220 | 0.029 | |
| embryonic development via the syncytial blastoderm | GO:0001700 | 148 | 0.028 | Fly |
| positive regulation of multicellular organismal process | GO:0051240 | 143 | 0.028 | |
| stem cell maintenance | GO:0019827 | 67 | 0.028 | |
| positive regulation of nucleic acid templated transcription | GO:1903508 | 266 | 0.027 | |
| negative regulation of rna biosynthetic process | GO:1902679 | 240 | 0.027 | |
| response to sterol | GO:0036314 | 34 | 0.027 | |
| negative regulation of gene expression epigenetic | GO:0045814 | 77 | 0.026 | |
| apoptotic process | GO:0006915 | 159 | 0.026 | |
| positive regulation of immune response | GO:0050778 | 63 | 0.026 | |
| cellular response to hormone stimulus | GO:0032870 | 44 | 0.025 | |
| regulation of phosphorus metabolic process | GO:0051174 | 210 | 0.025 | |
| positive regulation of nucleobase containing compound metabolic process | GO:0045935 | 332 | 0.025 | |
| positive regulation of nitrogen compound metabolic process | GO:0051173 | 354 | 0.025 | |
| neuron projection guidance | GO:0097485 | 241 | 0.025 | |
| cellular response to dna damage stimulus | GO:0006974 | 223 | 0.025 | |
| dna integrity checkpoint | GO:0031570 | 81 | 0.025 | |
| camera type eye development | GO:0043010 | 4 | 0.025 | |
| mitotic sister chromatid segregation | GO:0000070 | 87 | 0.025 | |
| imaginal disc derived appendage morphogenesis | GO:0035114 | 395 | 0.024 | |
| dendrite development | GO:0016358 | 204 | 0.024 | Fly |
| negative regulation of programmed cell death | GO:0043069 | 72 | 0.024 | |
| regulation of dna metabolic process | GO:0051052 | 34 | 0.024 | |
| mrna processing | GO:0006397 | 104 | 0.023 | |
| regulation of growth | GO:0040008 | 233 | 0.023 | |
| regulation of transport | GO:0051049 | 181 | 0.023 | |
| cellular protein localization | GO:0034613 | 160 | 0.023 | |
| chromatin silencing | GO:0006342 | 76 | 0.023 | |
| intracellular signal transduction | GO:0035556 | 300 | 0.022 | |
| regulation of dna templated transcription elongation | GO:0032784 | 17 | 0.022 | |
| defense response to bacterium | GO:0042742 | 178 | 0.022 | |
| taxis | GO:0042330 | 304 | 0.022 | |
| protein modification process | GO:0036211 | 438 | 0.022 | |
| regulation of transmembrane receptor protein serine threonine kinase signaling pathway | GO:0090092 | 38 | 0.022 | |
| negative regulation of cellular macromolecule biosynthetic process | GO:2000113 | 267 | 0.021 | |
| multicellular organismal reproductive behavior | GO:0033057 | 110 | 0.021 | |
| regulation of anatomical structure morphogenesis | GO:0022603 | 242 | 0.021 | |
| regulation of protein metabolic process | GO:0051246 | 256 | 0.020 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 145 | 0.020 | |
| negative regulation of rna metabolic process | GO:0051253 | 251 | 0.020 | |
| programmed cell death | GO:0012501 | 257 | 0.020 | |
| positive regulation of protein modification process | GO:0031401 | 58 | 0.020 | |
| cellular response to lipid | GO:0071396 | 20 | 0.020 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 3 | 0.020 | |
| regulation of transcription elongation from rna polymerase ii promoter | GO:0034243 | 15 | 0.019 | |
| cellular response to ketone | GO:1901655 | 17 | 0.019 | |
| intracellular transport | GO:0046907 | 228 | 0.019 | |
| cellular response to organic cyclic compound | GO:0071407 | 32 | 0.019 | |
| development of primary sexual characteristics | GO:0045137 | 50 | 0.019 | |
| positive regulation of rna biosynthetic process | GO:1902680 | 266 | 0.019 | |
| cellular ketone metabolic process | GO:0042180 | 24 | 0.019 | |
| positive regulation of multi organism process | GO:0043902 | 40 | 0.019 | |
| negative regulation of immune system process | GO:0002683 | 50 | 0.019 | |
| negative regulation of cellular biosynthetic process | GO:0031327 | 277 | 0.019 | |
| transcription elongation from rna polymerase ii promoter | GO:0006368 | 18 | 0.019 | |
| response to lipid | GO:0033993 | 38 | 0.019 | |
| protein complex biogenesis | GO:0070271 | 201 | 0.018 | |
| establishment or maintenance of cell polarity | GO:0007163 | 167 | 0.018 | |
| regulation of developmental growth | GO:0048638 | 174 | 0.018 | |
| autophagy | GO:0006914 | 108 | 0.018 | |
| cell fate specification | GO:0001708 | 71 | 0.018 | |
| dendrite morphogenesis | GO:0048813 | 199 | 0.018 | Fly |
| larval development | GO:0002164 | 104 | 0.018 | Worm |
| regulation of protein modification process | GO:0031399 | 112 | 0.017 | |
| genitalia development | GO:0048806 | 26 | 0.017 | |
| endomembrane system organization | GO:0010256 | 119 | 0.017 | |
| cellular response to transforming growth factor beta stimulus | GO:0071560 | 18 | 0.017 | |
| response to organic cyclic compound | GO:0014070 | 89 | 0.017 | |
| negative regulation of cellular component organization | GO:0051129 | 108 | 0.017 | |
| regulation of cellular localization | GO:0060341 | 136 | 0.017 | |
| response to ecdysone | GO:0035075 | 34 | 0.017 | |
| transmembrane receptor protein serine threonine kinase signaling pathway | GO:0007178 | 65 | 0.017 | |
| regulation of apoptotic process | GO:0042981 | 130 | 0.016 | |
| neural precursor cell proliferation | GO:0061351 | 75 | 0.016 | Fly |
| defense response to gram negative bacterium | GO:0050829 | 94 | 0.016 | |
| meiotic cell cycle | GO:0051321 | 171 | 0.016 | |
| positive regulation of cellular component biogenesis | GO:0044089 | 80 | 0.016 | |
| regulation of mrna metabolic process | GO:1903311 | 72 | 0.016 | |
| negative regulation of apoptotic process | GO:0043066 | 63 | 0.016 | |
| developmental maturation | GO:0021700 | 172 | 0.015 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 0 | 0.015 | |
| phagocytosis | GO:0006909 | 215 | 0.015 | |
| embryonic organ development | GO:0048568 | 50 | 0.015 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 54 | 0.015 | |
| regulation of cellular response to stress | GO:0080135 | 89 | 0.015 | |
| cellular amino acid metabolic process | GO:0006520 | 61 | 0.015 | |
| rna splicing via transesterification reactions | GO:0000375 | 73 | 0.015 | |
| neurological system process | GO:0050877 | 358 | 0.015 | |
| innate immune response | GO:0045087 | 144 | 0.015 | |
| negative regulation of multicellular organismal process | GO:0051241 | 142 | 0.014 | Worm |
| negative regulation of biosynthetic process | GO:0009890 | 277 | 0.014 | |
| renal tubule development | GO:0061326 | 64 | 0.014 | |
| gland morphogenesis | GO:0022612 | 145 | 0.013 | |
| purine nucleotide metabolic process | GO:0006163 | 146 | 0.013 | |
| salivary gland development | GO:0007431 | 162 | 0.013 | |
| ncrna metabolic process | GO:0034660 | 43 | 0.013 | |
| formation of a compartment boundary | GO:0060288 | 4 | 0.013 | |
| brain development | GO:0007420 | 120 | 0.013 | |
| cellular response to growth factor stimulus | GO:0071363 | 30 | 0.013 | |
| protein secretion | GO:0009306 | 45 | 0.013 | |
| histone lysine demethylation | GO:0070076 | 6 | 0.013 | |
| mitochondrial membrane organization | GO:0007006 | 3 | 0.013 | |
| compound eye morphogenesis | GO:0001745 | 249 | 0.013 | |
| embryonic morphogenesis | GO:0048598 | 206 | 0.013 | |
| growth | GO:0040007 | 359 | 0.013 | |
| regulation of hemocyte proliferation | GO:0035206 | 37 | 0.012 | |
| negative regulation of mitotic cell cycle | GO:0045930 | 109 | 0.012 | |
| sex differentiation | GO:0007548 | 81 | 0.012 | |
| muscle organ development | GO:0007517 | 127 | 0.012 | Fly |
| positive regulation of signal transduction | GO:0009967 | 223 | 0.012 | |
| response to abiotic stimulus | GO:0009628 | 341 | 0.012 | |
| rna catabolic process | GO:0006401 | 37 | 0.012 | |
| negative regulation of toll signaling pathway | GO:0045751 | 7 | 0.012 | |
| meiotic cell cycle process | GO:1903046 | 132 | 0.012 | |
| secretion by cell | GO:0032940 | 101 | 0.012 | |
| organic cyclic compound catabolic process | GO:1901361 | 168 | 0.012 | |
| multi organism reproductive behavior | GO:0044705 | 121 | 0.012 | |
| negative regulation of cell cycle | GO:0045786 | 116 | 0.012 | |
| regulation of cellular protein metabolic process | GO:0032268 | 243 | 0.011 | |
| response to ketone | GO:1901654 | 34 | 0.011 | |
| regulation of proteolysis | GO:0030162 | 87 | 0.011 | |
| salivary gland morphogenesis | GO:0007435 | 145 | 0.011 | |
| regulation of programmed cell death | GO:0043067 | 152 | 0.011 | |
| stem cell proliferation | GO:0072089 | 88 | 0.011 | Fly |
| regulation of proteasomal ubiquitin dependent protein catabolic process | GO:0032434 | 37 | 0.011 | |
| positive regulation of signaling | GO:0023056 | 243 | 0.011 | |
| negative regulation of cell death | GO:0060548 | 81 | 0.011 | |
| rna 3 end processing | GO:0031123 | 45 | 0.011 | |
| regulation of cell cycle | GO:0051726 | 291 | 0.011 | Fly |
| digestive tract morphogenesis | GO:0048546 | 127 | 0.011 | |
| axon guidance | GO:0007411 | 233 | 0.011 | |
| positive regulation of molecular function | GO:0044093 | 136 | 0.010 | |
| eye morphogenesis | GO:0048592 | 260 | 0.010 | |
| positive regulation of epidermal growth factor activated receptor activity | GO:0045741 | 1 | 0.010 | |
| body morphogenesis | GO:0010171 | 2 | 0.010 | |
| cell cycle g1 s phase transition | GO:0044843 | 31 | 0.010 | |
| heart development | GO:0007507 | 82 | 0.010 | |
