Drosophila melanogaster

100 known processes

Sfmbt (Dmel_CG16975)

Scm-related gene containing four mbt domains

(Aliases: dSFMBT,dSfmbt,Dmel\CG16975,CG16975,SFMBT)

Sfmbt biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of response to stimulusGO:00485852580.602
stem cell developmentGO:0048864790.597
negative regulation of signalingGO:00230572190.595
cellular response to chemical stimulusGO:00708871990.578
stem cell differentiationGO:00488631170.569
cellular response to organic substanceGO:00713101320.509
negative regulation of signal transductionGO:00099682060.456
negative regulation of cell communicationGO:00106482230.452
transcription from rna polymerase ii promoterGO:00063663680.428
Fly
dna damage checkpointGO:0000077780.328
mitotic dna integrity checkpointGO:0044774750.300
negative regulation of developmental processGO:00510932010.291
Worm
rna processingGO:00063961470.289
enzyme linked receptor protein signaling pathwayGO:00071671790.282
mrna metabolic processGO:00160711240.278
spindle organizationGO:00070512530.269
regulation of response to stressGO:00801342000.256
cell cycle phase transitionGO:00447701400.232
negative regulation of cell cycle phase transitionGO:19019881030.209
regulation of cell differentiationGO:00455953020.202
determination of adult lifespanGO:00083401370.197
response to oxygen containing compoundGO:19017002000.193
regulation of immune system processGO:00026821760.188
proteolysisGO:00065081920.165
response to organic substanceGO:00100332840.154
negative regulation of macromolecule biosynthetic processGO:00105582700.143
positive regulation of transcription dna templatedGO:00458932660.142
dna templated transcription elongationGO:0006354180.141
cell divisionGO:00513012480.140
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.131
regulation of immune responseGO:00507761180.128
immune responseGO:00069552460.127
regulation of mitotic cell cycleGO:00073461900.124
Fly
immune system processGO:00023763470.122
positive regulation of macromolecule biosynthetic processGO:00105572830.119
negative regulation of cellular metabolic processGO:00313243820.106
positive regulation of neuron projection regenerationGO:007057230.105
positive regulation of cellular biosynthetic processGO:00313283160.105
defense responseGO:00069523000.102
regulation of transcription from rna polymerase ii promoterGO:00063573780.102
Fly
response to external biotic stimulusGO:00432072930.101
regulation of cell developmentGO:00602842150.096
response to other organismGO:00517072930.091
multicellular organismal agingGO:00102591400.089
positive regulation of response to stimulusGO:00485843230.085
response to endogenous stimulusGO:00097191190.084
regulation of chromosome organizationGO:0033044640.084
negative regulation of nucleobase containing compound metabolic processGO:00459342610.081
cell proliferationGO:00082832990.077
Fly
organelle fissionGO:00482853400.074
cellular response to endogenous stimulusGO:0071495800.073
catabolic processGO:00090564090.073
negative regulation of cell differentiationGO:00455961430.070
macromolecular complex assemblyGO:00650032560.069
regulation of cell cycle phase transitionGO:19019871300.068
positive regulation of developmental processGO:00510941430.067
response to oxidative stressGO:0006979860.067
mitotic cell cycle phase transitionGO:00447721380.066
regulation of response to external stimulusGO:00321011150.063
regulation of mitotic cell cycle phase transitionGO:19019901300.062
defense response to other organismGO:00985422250.062
negative regulation of mitotic cell cycle phase transitionGO:19019911030.062
embryo development ending in birth or egg hatchingGO:00097921520.061
Mouse Fly
establishment of localization in cellGO:00516494020.060
Fly
eye developmentGO:00016543230.059
negative regulation of cell cycle processGO:00109481090.058
response to biotic stimulusGO:00096072940.058
positive regulation of biosynthetic processGO:00098913160.057
regulation of cell proliferationGO:00421271630.057
Fly
protein transportGO:00150311550.057
mitotic nuclear divisionGO:00070672130.057
cell cycle checkpointGO:0000075950.054
positive regulation of growthGO:0045927750.051
cellular catabolic processGO:00442483720.051
regulation of defense responseGO:00313471020.051
cellular response to oxygen containing compoundGO:1901701790.050
negative regulation of gene expressionGO:00106293870.049
regulation of immune effector processGO:0002697520.048
sensory organ morphogenesisGO:00905962600.048
macromolecule catabolic processGO:00090571610.046
positive regulation of rna metabolic processGO:00512542710.045
response to alcoholGO:0097305950.045
locomotory behaviorGO:00076261760.044
peptidyl lysine modificationGO:0018205570.043
cell deathGO:00082192790.043
mitotic g2 dna damage checkpointGO:0007095690.043
cellular macromolecule catabolic processGO:00442651360.042
positive regulation of cellular component organizationGO:00511301560.042
regulation of cell cycle processGO:00105641810.041
intracellular steroid hormone receptor signaling pathwayGO:0030518120.041
compound eye developmentGO:00487493070.041
protein complex assemblyGO:00064612000.040
sister chromatid segregationGO:0000819920.040
g1 s transition of mitotic cell cycleGO:0000082310.039
chemotaxisGO:00069352490.039
endocytosisGO:00068973100.039
mitotic cell cycle checkpointGO:0007093880.039
positive regulation of developmental growthGO:0048639620.038
organic substance transportGO:00717022570.038
stem cell divisionGO:0017145690.037
nuclear divisionGO:00002803320.037
mitotic spindle organizationGO:00070522200.037
establishment of protein localizationGO:00451841630.037
positive regulation of cell communicationGO:00106472500.036
deathGO:00162652840.036
regulation of molecular functionGO:00650092170.035
vesicle mediated transportGO:00161923810.034
mesenchymal cell developmentGO:001403110.034
cell adhesionGO:00071551360.033
meiosis iGO:0007127590.033
central nervous system developmentGO:00074172010.032
response to bacteriumGO:00096171980.032
covalent chromatin modificationGO:00165691060.032
chromatin modificationGO:00165681470.031
single organism catabolic processGO:00447122280.030
phosphorylationGO:00163102940.030
chromosome segregationGO:00070591570.030
gene silencingGO:00164581380.030
g2 dna damage checkpointGO:0031572690.030
protein localizationGO:00081042840.029
mitotic dna damage checkpointGO:0044773740.029
organic substance catabolic processGO:19015753080.029
cellular macromolecule localizationGO:00707272200.029
embryonic development via the syncytial blastodermGO:00017001480.028
Fly
positive regulation of multicellular organismal processGO:00512401430.028
stem cell maintenanceGO:0019827670.028
positive regulation of nucleic acid templated transcriptionGO:19035082660.027
negative regulation of rna biosynthetic processGO:19026792400.027
response to sterolGO:0036314340.027
negative regulation of gene expression epigeneticGO:0045814770.026
apoptotic processGO:00069151590.026
positive regulation of immune responseGO:0050778630.026
cellular response to hormone stimulusGO:0032870440.025
regulation of phosphorus metabolic processGO:00511742100.025
positive regulation of nucleobase containing compound metabolic processGO:00459353320.025
positive regulation of nitrogen compound metabolic processGO:00511733540.025
neuron projection guidanceGO:00974852410.025
cellular response to dna damage stimulusGO:00069742230.025
dna integrity checkpointGO:0031570810.025
camera type eye developmentGO:004301040.025
mitotic sister chromatid segregationGO:0000070870.025
imaginal disc derived appendage morphogenesisGO:00351143950.024
dendrite developmentGO:00163582040.024
Fly
negative regulation of programmed cell deathGO:0043069720.024
regulation of dna metabolic processGO:0051052340.024
mrna processingGO:00063971040.023
regulation of growthGO:00400082330.023
regulation of transportGO:00510491810.023
cellular protein localizationGO:00346131600.023
chromatin silencingGO:0006342760.023
intracellular signal transductionGO:00355563000.022
regulation of dna templated transcription elongationGO:0032784170.022
defense response to bacteriumGO:00427421780.022
taxisGO:00423303040.022
protein modification processGO:00362114380.022
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.022
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.021
multicellular organismal reproductive behaviorGO:00330571100.021
regulation of anatomical structure morphogenesisGO:00226032420.021
regulation of protein metabolic processGO:00512462560.020
posttranscriptional regulation of gene expressionGO:00106081450.020
negative regulation of rna metabolic processGO:00512532510.020
programmed cell deathGO:00125012570.020
positive regulation of protein modification processGO:0031401580.020
cellular response to lipidGO:0071396200.020
regulation of cellular ketone metabolic processGO:001056530.020
regulation of transcription elongation from rna polymerase ii promoterGO:0034243150.019
cellular response to ketoneGO:1901655170.019
intracellular transportGO:00469072280.019
cellular response to organic cyclic compoundGO:0071407320.019
development of primary sexual characteristicsGO:0045137500.019
positive regulation of rna biosynthetic processGO:19026802660.019
cellular ketone metabolic processGO:0042180240.019
positive regulation of multi organism processGO:0043902400.019
negative regulation of immune system processGO:0002683500.019
negative regulation of cellular biosynthetic processGO:00313272770.019
transcription elongation from rna polymerase ii promoterGO:0006368180.019
response to lipidGO:0033993380.019
protein complex biogenesisGO:00702712010.018
establishment or maintenance of cell polarityGO:00071631670.018
regulation of developmental growthGO:00486381740.018
autophagyGO:00069141080.018
cell fate specificationGO:0001708710.018
dendrite morphogenesisGO:00488131990.018
Fly
larval developmentGO:00021641040.018
Worm
regulation of protein modification processGO:00313991120.017
genitalia developmentGO:0048806260.017
endomembrane system organizationGO:00102561190.017
cellular response to transforming growth factor beta stimulusGO:0071560180.017
response to organic cyclic compoundGO:0014070890.017
negative regulation of cellular component organizationGO:00511291080.017
regulation of cellular localizationGO:00603411360.017
response to ecdysoneGO:0035075340.017
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.017
regulation of apoptotic processGO:00429811300.016
neural precursor cell proliferationGO:0061351750.016
Fly
defense response to gram negative bacteriumGO:0050829940.016
meiotic cell cycleGO:00513211710.016
positive regulation of cellular component biogenesisGO:0044089800.016
regulation of mrna metabolic processGO:1903311720.016
negative regulation of apoptotic processGO:0043066630.016
developmental maturationGO:00217001720.015
regulation of cellular amino acid metabolic processGO:000652100.015
phagocytosisGO:00069092150.015
embryonic organ developmentGO:0048568500.015
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.015
regulation of cellular response to stressGO:0080135890.015
cellular amino acid metabolic processGO:0006520610.015
rna splicing via transesterification reactionsGO:0000375730.015
neurological system processGO:00508773580.015
innate immune responseGO:00450871440.015
negative regulation of multicellular organismal processGO:00512411420.014
Worm
negative regulation of biosynthetic processGO:00098902770.014
renal tubule developmentGO:0061326640.014
gland morphogenesisGO:00226121450.013
purine nucleotide metabolic processGO:00061631460.013
salivary gland developmentGO:00074311620.013
ncrna metabolic processGO:0034660430.013
formation of a compartment boundaryGO:006028840.013
brain developmentGO:00074201200.013
cellular response to growth factor stimulusGO:0071363300.013
protein secretionGO:0009306450.013
histone lysine demethylationGO:007007660.013
mitochondrial membrane organizationGO:000700630.013
compound eye morphogenesisGO:00017452490.013
embryonic morphogenesisGO:00485982060.013
growthGO:00400073590.013
regulation of hemocyte proliferationGO:0035206370.012
negative regulation of mitotic cell cycleGO:00459301090.012
sex differentiationGO:0007548810.012
muscle organ developmentGO:00075171270.012
Fly
positive regulation of signal transductionGO:00099672230.012
response to abiotic stimulusGO:00096283410.012
rna catabolic processGO:0006401370.012
negative regulation of toll signaling pathwayGO:004575170.012
meiotic cell cycle processGO:19030461320.012
secretion by cellGO:00329401010.012
organic cyclic compound catabolic processGO:19013611680.012
multi organism reproductive behaviorGO:00447051210.012
negative regulation of cell cycleGO:00457861160.012
regulation of cellular protein metabolic processGO:00322682430.011
response to ketoneGO:1901654340.011
regulation of proteolysisGO:0030162870.011
salivary gland morphogenesisGO:00074351450.011
regulation of programmed cell deathGO:00430671520.011
stem cell proliferationGO:0072089880.011
Fly
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.011
positive regulation of signalingGO:00230562430.011
negative regulation of cell deathGO:0060548810.011
rna 3 end processingGO:0031123450.011
regulation of cell cycleGO:00517262910.011
Fly
digestive tract morphogenesisGO:00485461270.011
axon guidanceGO:00074112330.011
positive regulation of molecular functionGO:00440931360.010
eye morphogenesisGO:00485922600.010
positive regulation of epidermal growth factor activated receptor activityGO:004574110.010
body morphogenesisGO:001017120.010
cell cycle g1 s phase transitionGO:0044843310.010
heart developmentGO:0007507820.010

Sfmbt disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.011
disease of cellular proliferationDOID:1456600.011