Drosophila melanogaster

159 known processes

Mnn1 (Dmel_CG13778)

Menin 1

(Aliases: Menin1,mnn1,MEN1,CG13778,Dmel\CG13778,menin,CG33266)

Mnn1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to dna damage stimulusGO:00069742230.715
protein modification processGO:00362114380.483
Mouse
cellular catabolic processGO:00442483720.412
chromosome organizationGO:00512763600.387
Mouse
multicellular organismal agingGO:00102591400.356
positive regulation of rna biosynthetic processGO:19026802660.296
Mouse
negative regulation of rna metabolic processGO:00512532510.291
Mouse
regulation of response to stressGO:00801342000.286
negative regulation of mitotic cell cycleGO:00459301090.282
agingGO:00075681430.273
negative regulation of cell cycle processGO:00109481090.264
compound eye developmentGO:00487493070.254
negative regulation of cell cycleGO:00457861160.243
positive regulation of macromolecule metabolic processGO:00106044050.243
Mouse
programmed cell deathGO:00125012570.241
Mouse
immune system processGO:00023763470.234
Mouse
phosphorylationGO:00163102940.212
regulation of phosphorylationGO:00423251470.202
negative regulation of cell cycle phase transitionGO:19019881030.199
negative regulation of biosynthetic processGO:00098902770.197
Mouse
positive regulation of rna metabolic processGO:00512542710.184
Mouse
positive regulation of nucleobase containing compound metabolic processGO:00459353320.180
Mouse
negative regulation of response to stimulusGO:00485852580.175
negative regulation of cellular metabolic processGO:00313243820.162
negative regulation of cellular biosynthetic processGO:00313272770.161
Mouse
regulation of organelle organizationGO:00330431960.146
Mouse
regulation of cell cycle processGO:00105641810.141
homeostatic processGO:00425921990.132
Mouse
germarium derived egg chamber formationGO:00072931010.131
response to abiotic stimulusGO:00096283410.129
hemopoiesisGO:0030097460.124
Mouse
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.122
Mouse
dna metabolic processGO:00062592270.117
dna recombinationGO:0006310320.116
regulation of developmental pigmentationGO:0048070240.114
dna replicationGO:0006260480.109
actin cytoskeleton organizationGO:00300362060.103
response to starvationGO:0042594970.102
gene silencingGO:00164581380.100
negative regulation of nitrogen compound metabolic processGO:00511722650.099
Mouse
regulation of immune system processGO:00026821760.099
positive regulation of nucleic acid templated transcriptionGO:19035082660.097
Mouse
regulation of phosphorus metabolic processGO:00511742100.095
response to oxygen containing compoundGO:19017002000.091
regulation of molecular functionGO:00650092170.089
Mouse
regulation of protein metabolic processGO:00512462560.088
Mouse
positive regulation of gene expressionGO:00106282900.087
Mouse
single organism catabolic processGO:00447122280.087
regulation of cellular protein metabolic processGO:00322682430.085
Mouse
cellular protein modification processGO:00064644380.085
Mouse
response to uvGO:0009411240.084
body morphogenesisGO:001017120.084
amine metabolic processGO:0009308120.082
positive regulation of cysteine type endopeptidase activityGO:2001056240.082
Mouse
regulation of cellular response to stressGO:0080135890.082
proteolysisGO:00065081920.081
Mouse
response to alcoholGO:0097305950.078
negative regulation of chromosome organizationGO:2001251190.077
nucleobase containing compound catabolic processGO:00346551650.076
response to light stimulusGO:00094161240.076
cellular amine metabolic processGO:0044106120.074
negative regulation of nucleic acid templated transcriptionGO:19035072400.073
Mouse
dna damage checkpointGO:0000077780.073
negative regulation of gene expressionGO:00106293870.073
Mouse
single organism behaviorGO:00447083910.070
protein phosphorylationGO:00064681690.069
compound eye morphogenesisGO:00017452490.069
regulation of cellular ketone metabolic processGO:001056530.065
determination of adult lifespanGO:00083401370.065
regulation of protein kinase activityGO:0045859510.065
dorsal closureGO:0007391790.064
establishment of localization in cellGO:00516494020.064
regulation of protein modification processGO:00313991120.063
Mouse
regulation of chromatin organizationGO:1902275320.061
Mouse
regulation of multi organism processGO:00439001310.061
negative regulation of cell communicationGO:00106482230.061
purine ribonucleotide catabolic processGO:00091541090.060
regulation of intracellular signal transductionGO:19025312360.060
regulation of mitotic cell cycleGO:00073461900.059
endocytosisGO:00068973100.057
chromosome segregationGO:00070591570.057
organonitrogen compound metabolic processGO:19015643180.056
positive regulation of response to stimulusGO:00485843230.056
negative regulation of gene expression epigeneticGO:0045814770.055
internal protein amino acid acetylationGO:0006475380.054
deathGO:00162652840.054
Mouse
apoptotic processGO:00069151590.054
Mouse
stem cell proliferationGO:0072089880.054
single organism intracellular transportGO:19025822070.053
protein transportGO:00150311550.053
small molecule metabolic processGO:00442813050.052
intrinsic apoptotic signaling pathwayGO:0097193160.052
single organism cellular localizationGO:19025801800.052
cellular response to oxygen containing compoundGO:1901701790.051
regulation of phosphate metabolic processGO:00192202100.051
double strand break repair via homologous recombinationGO:0000724130.050
negative regulation of transcription dna templatedGO:00458922370.049
Mouse
connective tissue developmentGO:006144830.049
cellular response to starvationGO:0009267610.049
regulation of epithelial cell proliferationGO:005067840.049
negative regulation of signalingGO:00230572190.048
protein modification by small protein conjugation or removalGO:00706471060.048
recombinational repairGO:0000725130.048
organic substance catabolic processGO:19015753080.047
glycosyl compound metabolic processGO:19016571270.046
regulation of cellular amine metabolic processGO:003323830.046
embryonic morphogenesisGO:00485982060.046
Mouse
cell divisionGO:00513012480.044
Mouse
negative regulation of cell deathGO:0060548810.044
purine nucleoside catabolic processGO:00061521120.044
positive regulation of nitrogen compound metabolic processGO:00511733540.044
Mouse
negative regulation of rna biosynthetic processGO:19026792400.044
Mouse
regulation of defense responseGO:00313471020.044
intracellular protein transportGO:00068861040.043
dna repairGO:0006281540.043
covalent chromatin modificationGO:00165691060.043
Mouse
regulation of cell deathGO:00109411730.043
Mouse
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630110.042
signal transduction by phosphorylationGO:00230141070.042
cell deathGO:00082192790.042
Mouse
cell proliferationGO:00082832990.041
Mouse
positive regulation of cellular biosynthetic processGO:00313283160.041
Mouse
nucleotide metabolic processGO:00091171610.041
dna synthesis involved in dna repairGO:000073150.041
ribonucleoside triphosphate metabolic processGO:00091991190.041
apoptotic signaling pathwayGO:0097190270.040
aromatic compound catabolic processGO:00194391660.040
imaginal disc derived wing morphogenesisGO:00074763370.040
purine ribonucleotide metabolic processGO:00091501450.040
regulation of catabolic processGO:00098941700.040
regulation of cell cycle phase transitionGO:19019871300.040
glycosyl compound catabolic processGO:19016581120.039
response to organic substanceGO:00100332840.039
purine nucleotide catabolic processGO:00061951090.039
hemocyte differentiationGO:0042386380.039
response to radiationGO:00093141550.038
positive regulation of transcription dna templatedGO:00458932660.038
Mouse
intracellular signal transductionGO:00355563000.037
establishment of protein localizationGO:00451841630.037
catabolic processGO:00090564090.036
cellular response to radiationGO:0071478520.036
protein localization to nucleusGO:0034504550.036
regulation of gene silencingGO:0060968630.036
purine ribonucleoside metabolic processGO:00461281270.035
eye developmentGO:00016543230.035
regulation of cellular amino acid metabolic processGO:000652100.035
protein modification by small protein conjugationGO:0032446790.035
negative regulation of cellular protein metabolic processGO:0032269850.034
regulation of multicellular organismal developmentGO:20000264140.034
regulation of programmed cell deathGO:00430671520.034
Mouse
stress activated mapk cascadeGO:0051403520.033
chromatin modificationGO:00165681470.033
Mouse
purine containing compound metabolic processGO:00725211550.033
chromatin organizationGO:00063252070.033
Mouse
double strand break repair via synthesis dependent strand annealingGO:004500360.032
establishment or maintenance of microtubule cytoskeleton polarityGO:0030951410.032
heterocycle catabolic processGO:00467001660.032
regulation of catalytic activityGO:00507901850.032
Mouse
axis specificationGO:00097981670.032
wing disc morphogenesisGO:00074723440.031
response to organonitrogen compoundGO:0010243750.031
peptidyl amino acid modificationGO:00181931050.031
positive regulation of catabolic processGO:00098961050.031
regulation of lipid storageGO:0010883220.031
mitotic cell cycle checkpointGO:0007093880.031
carbohydrate derivative metabolic processGO:19011352170.031
negative regulation of mitotic cell cycle phase transitionGO:19019911030.030
purine nucleotide metabolic processGO:00061631460.030
negative regulation of apoptotic processGO:0043066630.030
mitotic spindle organizationGO:00070522200.030
regulation of transcription from rna polymerase ii promoterGO:00063573780.030
Mouse
positive regulation of cell communicationGO:00106472500.029
adult behaviorGO:00305341370.029
dna double strand break processingGO:000072930.029
stem cell differentiationGO:00488631170.029
nucleoside phosphate catabolic processGO:19012921100.029
nucleotide excision repairGO:000628980.029
positive regulation of programmed cell deathGO:0043068620.029
Mouse
tissue morphogenesisGO:00487292970.029
ribonucleoside catabolic processGO:00424541120.028
cellular response to organic substanceGO:00713101320.028
activation of cysteine type endopeptidase activityGO:0097202170.028
nucleoside triphosphate catabolic processGO:00091431080.028
macromolecule catabolic processGO:00090571610.028
negative regulation of nucleobase containing compound metabolic processGO:00459342610.028
Mouse
regulation of mitotic cell cycle phase transitionGO:19019901300.027
cell cycle phase transitionGO:00447701400.027
response to nitrogen compoundGO:1901698900.027
cellular protein catabolic processGO:0044257830.027
response to paraquatGO:190156240.027
nucleobase containing small molecule metabolic processGO:00550861740.027
histone acetylationGO:0016573380.027
establishment of protein localization to organelleGO:0072594620.027
organelle fissionGO:00482853400.027
atp metabolic processGO:0046034490.027
organophosphate metabolic processGO:00196371950.027
organic cyclic compound catabolic processGO:19013611680.026
regulation of transferase activityGO:0051338580.026
response to endogenous stimulusGO:00097191190.026
nucleoside catabolic processGO:00091641120.026
regulation of stress activated protein kinase signaling cascadeGO:0070302420.026
negative regulation of phosphorylationGO:0042326350.026
negative regulation of molecular functionGO:0044092510.026
organonitrogen compound catabolic processGO:19015651280.025
positive regulation of cellular catabolic processGO:0031331950.025
response to other organismGO:00517072930.025
male gamete generationGO:00482322010.025
nucleoside triphosphate metabolic processGO:00091411200.025
stress activated protein kinase signaling cascadeGO:0031098550.024
positive regulation of immune system processGO:0002684680.024
nucleoside phosphate metabolic processGO:00067531620.024
response to ionizing radiationGO:0010212320.024
signal transduction in response to dna damageGO:004277030.024
secretion by cellGO:00329401010.024
protein maturationGO:0051604710.024
vesicle mediated transportGO:00161923810.024
organic substance transportGO:00717022570.023
establishment or maintenance of cytoskeleton polarityGO:0030952440.023
positive regulation of macromolecule biosynthetic processGO:00105572830.023
Mouse
positive regulation of catalytic activityGO:00430851180.023
Mouse
cellular response to endogenous stimulusGO:0071495800.023
meiosis iGO:0007127590.023
cytoplasmic transportGO:00164821300.022
regulation of apoptotic processGO:00429811300.022
Mouse
positive regulation of molecular functionGO:00440931360.022
Mouse
regulation of cell cycleGO:00517262910.022
dorsal ventral pattern formationGO:00099531330.022
ribonucleotide metabolic processGO:00092591450.022
lysosomal transportGO:0007041130.022
cell activationGO:000177590.022
regulation of protein transportGO:0051223570.022
histone modificationGO:00165701060.022
Mouse
transcription from rna polymerase ii promoterGO:00063663680.022
Mouse
positive regulation of intracellular signal transductionGO:19025331160.021
negative regulation of peptidyl tyrosine phosphorylationGO:005073260.021
purine nucleoside metabolic processGO:00422781270.021
carbohydrate derivative catabolic processGO:19011361180.021
regulation of protein phosphorylationGO:0001932640.021
anterograde axon cargo transportGO:000808960.021
nucleoside metabolic processGO:00091161270.021
anatomical structure homeostasisGO:0060249970.021
photoreceptor cell developmentGO:0042461960.020
developmental programmed cell deathGO:00106231380.020
modification dependent protein catabolic processGO:0019941780.020
purine containing compound catabolic processGO:00725231120.020
regulation of localizationGO:00328792750.020
positive regulation of biosynthetic processGO:00098913160.020
Mouse
camera type eye developmentGO:004301040.019
purine nucleoside triphosphate metabolic processGO:00091441190.019
regulation of response to dna damage stimulusGO:2001020230.019
negative regulation of developmental processGO:00510932010.019
Mouse
nuclear divisionGO:00002803320.019
regulation of immune effector processGO:0002697520.019
regulation of cellular catabolic processGO:00313291570.019
cellular macromolecule catabolic processGO:00442651360.019
cuticle developmentGO:0042335860.018
gastrulationGO:0007369700.018
regulation of transportGO:00510491810.018
secretionGO:00469031090.018
cellular response to nutrient levelsGO:0031669620.018
dorsal ventral axis specificationGO:0009950660.018
regulation of chromosome organizationGO:0033044640.018
Mouse
regulation of cellular component biogenesisGO:00440872010.018
phagocytosisGO:00069092150.018
regulation of proteolysisGO:0030162870.018
Mouse
autophagyGO:00069141080.018
establishment or maintenance of cell polarityGO:00071631670.018
negative regulation of protein metabolic processGO:0051248850.018
regulation of phosphatase activityGO:001092130.018
positive regulation of cell differentiationGO:0045597640.018
Mouse
proteolysis involved in cellular protein catabolic processGO:0051603830.017
cellular macromolecular complex assemblyGO:00346221530.017
nuclear transportGO:0051169720.017
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.017
morphogenesis of an epitheliumGO:00020092760.017
regulation of cell cycle g1 s phase transitionGO:1902806230.017
pigmentationGO:0043473750.017
purine nucleoside triphosphate catabolic processGO:00091461080.017
protein localization to organelleGO:0033365820.017
morphogenesis of follicular epitheliumGO:0016333360.017
positive regulation of cellular amine metabolic processGO:003324000.017
positive regulation of mapk cascadeGO:0043410630.017
mitotic cell cycle phase transitionGO:00447721380.017
imaginal disc fusionGO:0046528190.017
cellular response to external stimulusGO:0071496660.016
regionalizationGO:00030024160.016
purine ribonucleoside triphosphate catabolic processGO:00092071080.016
regulation of response to biotic stimulusGO:0002831630.016
regulation of cell differentiationGO:00455953020.016
Mouse
protein processingGO:0016485680.016
meiotic cell cycleGO:00513211710.016
negative regulation of phosphorus metabolic processGO:0010563450.016
dna templated transcription elongationGO:0006354180.016
protein targetingGO:0006605640.016
embryonic development via the syncytial blastodermGO:00017001480.016
actin filament based processGO:00300292200.016
protein ubiquitinationGO:0016567700.016
ribonucleoside triphosphate catabolic processGO:00092031080.016
regulation of kinase activityGO:0043549530.016
positive regulation of multicellular organismal processGO:00512401430.015
Mouse
spindle organizationGO:00070512530.015
regulation of mapk cascadeGO:0043408920.015
cellular nitrogen compound catabolic processGO:00442701650.015
behavioral response to ethanolGO:0048149490.015
morphogenesis of embryonic epitheliumGO:0016331940.015
cell cycle checkpointGO:0000075950.015
purine ribonucleoside catabolic processGO:00461301120.015
negative regulation of signal transductionGO:00099682060.015
compound eye retinal cell programmed cell deathGO:0046667230.015
cellular response to chemical stimulusGO:00708871990.015
single organism biosynthetic processGO:00447112060.015
negative regulation of catalytic activityGO:0043086420.015
positive regulation of lipid metabolic processGO:004583440.015
immune system developmentGO:0002520570.015
Mouse
oocyte microtubule cytoskeleton organizationGO:0016325350.015
double strand break repairGO:0006302260.015
r7 cell differentiationGO:0045466430.015
protein acetylationGO:0006473390.014
imaginal disc derived appendage developmentGO:00487373990.014
positive regulation of protein catabolic processGO:0045732340.014
cellular response to abiotic stimulusGO:0071214580.014
regulation of stem cell proliferationGO:0072091400.014
regulation of peptidase activityGO:0052547390.014
Mouse
regulation of cell proliferationGO:00421271630.014
Mouse
negative regulation of protein modification processGO:0031400290.014
instar larval developmentGO:0002168550.014
localization of cellGO:00516742570.014
regulation of autophagyGO:0010506620.014
nucleotide catabolic processGO:00091661090.014
positive regulation of apoptotic processGO:0043065470.014
Mouse
negative regulation of macromolecule biosynthetic processGO:00105582700.014
Mouse
regulation of cell motilityGO:2000145230.013
catechol containing compound biosynthetic processGO:000971330.013
neurological system processGO:00508773580.013
cellular response to nitrogen compoundGO:1901699510.013
purine ribonucleoside triphosphate metabolic processGO:00092051190.013
cell junction organizationGO:0034330570.013
regulation of protein localizationGO:0032880760.013
jnk cascadeGO:0007254500.013
cellular protein complex assemblyGO:0043623710.013
dna integrity checkpointGO:0031570810.013
cortical actin cytoskeleton organizationGO:0030866240.013
regulation of histone deacetylationGO:003106320.013
ras protein signal transductionGO:0007265880.012
negative regulation of programmed cell deathGO:0043069720.012
regulation of reproductive processGO:2000241540.012
cellular response to extracellular stimulusGO:0031668640.012
g2 dna damage checkpointGO:0031572690.012
regulation of locomotionGO:0040012420.012
transition metal ion transportGO:0000041160.012
molting cycleGO:0042303560.012
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.012
Mouse
positive regulation of developmental processGO:00510941430.012
Mouse
gastrulation involving germ band extensionGO:0010004360.012
purine ribonucleoside monophosphate metabolic processGO:0009167500.012
response to organic cyclic compoundGO:0014070890.012
cellular macromolecule localizationGO:00707272200.012
cellular response to arsenic containing substanceGO:007124360.012
mitotic dna damage checkpointGO:0044773740.012
regulation of proteasomal protein catabolic processGO:0061136390.012
postreplication repairGO:000630120.012
regulation of cell morphogenesisGO:00226041630.012
cellular ketone metabolic processGO:0042180240.012
cellular homeostasisGO:0019725800.011
retina development in camera type eyeGO:006004140.011
regulation of compound eye retinal cell programmed cell deathGO:0046669180.011
oxidoreduction coenzyme metabolic processGO:000673320.011
protein localizationGO:00081042840.011
response to nutrient levelsGO:00316671140.011
regulation of meiosisGO:004002030.011
regulation of response to external stimulusGO:00321011150.011
peptide transportGO:0015833100.011
chromatin silencingGO:0006342760.011
cell growthGO:00160491080.011
protein catabolic processGO:00301631010.011
synaptic transmissionGO:00072682880.011
cell maturationGO:00484691440.011
regulation of cell divisionGO:0051302720.011
Mouse
regulation of endopeptidase activityGO:0052548360.011
Mouse
regulation of cellular localizationGO:00603411360.011
sensory organ morphogenesisGO:00905962600.011
compound eye photoreceptor cell differentiationGO:00017511400.010
regulation of hemocyte differentiationGO:0045610220.010
gastrulation with mouth forming firstGO:0001703360.010
ribonucleotide catabolic processGO:00092611090.010
long term memoryGO:0007616620.010
oocyte dorsal ventral axis specificationGO:0007310340.010
ribonucleoside monophosphate metabolic processGO:0009161510.010
mesenchymal cell differentiationGO:004876210.010
cellular response to ionizing radiationGO:0071479150.010
positive regulation of signalingGO:00230562430.010

Mnn1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.049
cancerDOID:16200.049
organ system cancerDOID:005068600.049
disease of anatomical entityDOID:700.034
acquired metabolic diseaseDOID:006015800.024
disease of metabolismDOID:001466700.024