| positive regulation of macromolecule metabolic process | GO:0010604 | 405 | 0.763 | Human |
| positive regulation of gene expression | GO:0010628 | 290 | 0.688 | Human |
| multi multicellular organism process | GO:0044706 | 123 | 0.629 | |
| positive regulation of nitrogen compound metabolic process | GO:0051173 | 354 | 0.548 | Human |
| positive regulation of biosynthetic process | GO:0009891 | 316 | 0.445 | |
| positive regulation of rna metabolic process | GO:0051254 | 271 | 0.422 | Human |
| regulation of transcription from rna polymerase ii promoter | GO:0006357 | 378 | 0.401 | |
| negative regulation of rna metabolic process | GO:0051253 | 251 | 0.359 | |
| negative regulation of cellular biosynthetic process | GO:0031327 | 277 | 0.357 | |
| positive regulation of macromolecule biosynthetic process | GO:0010557 | 283 | 0.318 | |
| negative regulation of nucleobase containing compound metabolic process | GO:0045934 | 261 | 0.307 | |
| gene silencing | GO:0016458 | 138 | 0.300 | |
| positive regulation of transcription from rna polymerase ii promoter | GO:0045944 | 204 | 0.279 | |
| negative regulation of nucleic acid templated transcription | GO:1903507 | 240 | 0.275 | |
| locomotory behavior | GO:0007626 | 176 | 0.252 | |
| sex determination | GO:0007530 | 18 | 0.243 | |
| positive regulation of nucleic acid templated transcription | GO:1903508 | 266 | 0.235 | |
| intracellular signal transduction | GO:0035556 | 300 | 0.224 | |
| negative regulation of biosynthetic process | GO:0009890 | 277 | 0.221 | |
| negative regulation of cellular metabolic process | GO:0031324 | 382 | 0.214 | |
| positive regulation of rna biosynthetic process | GO:1902680 | 266 | 0.214 | |
| negative regulation of cell cycle | GO:0045786 | 116 | 0.201 | |
| mrna processing | GO:0006397 | 104 | 0.176 | |
| chromatin modification | GO:0016568 | 147 | 0.167 | |
| transcription initiation from rna polymerase ii promoter | GO:0006367 | 25 | 0.167 | |
| oocyte differentiation | GO:0009994 | 145 | 0.164 | |
| response to abiotic stimulus | GO:0009628 | 341 | 0.148 | |
| response to oxygen containing compound | GO:1901700 | 200 | 0.143 | Rat |
| regulation of phosphorus metabolic process | GO:0051174 | 210 | 0.141 | |
| negative regulation of rna biosynthetic process | GO:1902679 | 240 | 0.139 | |
| negative regulation of mitotic cell cycle | GO:0045930 | 109 | 0.136 | |
| positive regulation of cellular biosynthetic process | GO:0031328 | 316 | 0.129 | |
| mitotic cell cycle phase transition | GO:0044772 | 138 | 0.127 | |
| single organism behavior | GO:0044708 | 391 | 0.127 | |
| negative regulation of cellular macromolecule biosynthetic process | GO:2000113 | 267 | 0.124 | |
| positive regulation of phosphate metabolic process | GO:0045937 | 139 | 0.123 | |
| spindle organization | GO:0007051 | 253 | 0.118 | |
| transcription from rna polymerase ii promoter | GO:0006366 | 368 | 0.115 | |
| regulation of cell cycle phase transition | GO:1901987 | 130 | 0.115 | |
| regulation of cell cycle | GO:0051726 | 291 | 0.113 | |
| mitotic nuclear division | GO:0007067 | 213 | 0.111 | |
| axonogenesis | GO:0007409 | 290 | 0.111 | |
| regulation of localization | GO:0032879 | 275 | 0.107 | |
| regulation of phosphate metabolic process | GO:0019220 | 210 | 0.106 | |
| posttranscriptional gene silencing by rna | GO:0035194 | 45 | 0.104 | |
| phosphorylation | GO:0016310 | 294 | 0.103 | |
| segmentation | GO:0035282 | 207 | 0.100 | |
| cytoskeleton dependent cytokinesis | GO:0061640 | 81 | 0.097 | |
| eye photoreceptor cell development | GO:0042462 | 81 | 0.093 | |
| negative regulation of organelle organization | GO:0010639 | 56 | 0.093 | |
| negative regulation of gene expression | GO:0010629 | 387 | 0.090 | |
| imaginal disc growth | GO:0007446 | 37 | 0.089 | |
| taxis | GO:0042330 | 304 | 0.087 | |
| regulation of transport | GO:0051049 | 181 | 0.087 | |
| sister chromatid segregation | GO:0000819 | 92 | 0.087 | |
| regulation of multicellular organismal development | GO:2000026 | 414 | 0.087 | |
| regulation of meiosis | GO:0040020 | 3 | 0.086 | |
| mitotic cytokinesis | GO:0000281 | 50 | 0.085 | |
| carbohydrate derivative metabolic process | GO:1901135 | 217 | 0.085 | |
| dna damage checkpoint | GO:0000077 | 78 | 0.083 | |
| reproductive system development | GO:0061458 | 74 | 0.082 | |
| developmental programmed cell death | GO:0010623 | 138 | 0.081 | |
| cognition | GO:0050890 | 141 | 0.078 | |
| regulation of gene expression epigenetic | GO:0040029 | 128 | 0.074 | |
| positive regulation of nucleobase containing compound metabolic process | GO:0045935 | 332 | 0.073 | Human |
| multi organism behavior | GO:0051705 | 175 | 0.068 | |
| establishment of localization in cell | GO:0051649 | 402 | 0.066 | |
| nuclear division | GO:0000280 | 332 | 0.066 | |
| positive regulation of transcription dna templated | GO:0045893 | 266 | 0.064 | |
| regulation of ras protein signal transduction | GO:0046578 | 93 | 0.061 | |
| single organism intracellular transport | GO:1902582 | 207 | 0.061 | |
| cellular response to dna damage stimulus | GO:0006974 | 223 | 0.061 | |
| chemotaxis | GO:0006935 | 249 | 0.061 | |
| organophosphate metabolic process | GO:0019637 | 195 | 0.060 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 145 | 0.059 | |
| neuron projection guidance | GO:0097485 | 241 | 0.058 | |
| development of primary sexual characteristics | GO:0045137 | 50 | 0.057 | |
| appendage morphogenesis | GO:0035107 | 397 | 0.055 | |
| positive regulation of signaling | GO:0023056 | 243 | 0.052 | |
| dna templated transcription initiation | GO:0006352 | 25 | 0.052 | |
| regulation of mrna metabolic process | GO:1903311 | 72 | 0.050 | |
| regulation of gene silencing | GO:0060968 | 63 | 0.049 | |
| female sex differentiation | GO:0046660 | 20 | 0.048 | |
| sensory organ morphogenesis | GO:0090596 | 260 | 0.048 | |
| male gamete generation | GO:0048232 | 201 | 0.048 | |
| cell death | GO:0008219 | 279 | 0.047 | |
| regulation of cell cycle process | GO:0010564 | 181 | 0.046 | |
| rna processing | GO:0006396 | 147 | 0.046 | |
| mitotic sister chromatid segregation | GO:0000070 | 87 | 0.045 | |
| chromatin organization | GO:0006325 | 207 | 0.045 | |
| mitotic spindle organization | GO:0007052 | 220 | 0.045 | |
| cell cycle phase transition | GO:0044770 | 140 | 0.045 | |
| rna splicing | GO:0008380 | 83 | 0.043 | |
| negative regulation of cell cycle process | GO:0010948 | 109 | 0.043 | |
| regulation of mitotic metaphase anaphase transition | GO:0030071 | 26 | 0.043 | |
| sex differentiation | GO:0007548 | 81 | 0.042 | |
| microtubule cytoskeleton organization involved in mitosis | GO:1902850 | 52 | 0.042 | |
| negative regulation of gene expression epigenetic | GO:0045814 | 77 | 0.042 | |
| dna conformation change | GO:0071103 | 105 | 0.042 | |
| negative regulation of meiotic cell cycle | GO:0051447 | 2 | 0.042 | |
| mitotic g2 m transition checkpoint | GO:0044818 | 70 | 0.042 | |
| regulation of intracellular signal transduction | GO:1902531 | 236 | 0.041 | |
| cytoplasmic transport | GO:0016482 | 130 | 0.041 | |
| chromatin remodeling | GO:0006338 | 72 | 0.039 | |
| myofibril assembly | GO:0030239 | 36 | 0.039 | |
| gonad development | GO:0008406 | 50 | 0.039 | |
| oocyte development | GO:0048599 | 124 | 0.038 | |
| negative regulation of transcription from rna polymerase ii promoter | GO:0000122 | 119 | 0.038 | |
| negative regulation of cellular component organization | GO:0051129 | 108 | 0.037 | |
| negative regulation of nitrogen compound metabolic process | GO:0051172 | 265 | 0.037 | |
| organelle fission | GO:0048285 | 340 | 0.037 | |
| developmental maturation | GO:0021700 | 172 | 0.036 | |
| regulation of mitotic cell cycle | GO:0007346 | 190 | 0.036 | |
| negative regulation of macromolecule biosynthetic process | GO:0010558 | 270 | 0.035 | |
| regulation of meiotic cell cycle | GO:0051445 | 9 | 0.035 | |
| developmental growth | GO:0048589 | 280 | 0.035 | |
| multi organism reproductive behavior | GO:0044705 | 121 | 0.034 | |
| imaginal disc derived appendage development | GO:0048737 | 399 | 0.033 | |
| positive regulation of phosphorylation | GO:0042327 | 87 | 0.032 | |
| axon guidance | GO:0007411 | 233 | 0.032 | |
| chromatin mediated maintenance of transcription | GO:0048096 | 7 | 0.032 | |
| organelle assembly | GO:0070925 | 198 | 0.032 | |
| negative regulation of cellular catabolic process | GO:0031330 | 34 | 0.031 | |
| response to external biotic stimulus | GO:0043207 | 293 | 0.031 | |
| response to radiation | GO:0009314 | 155 | 0.030 | |
| regulation of chromatin silencing | GO:0031935 | 36 | 0.030 | |
| negative regulation of mitotic cell cycle phase transition | GO:1901991 | 103 | 0.030 | |
| mrna splice site selection | GO:0006376 | 1 | 0.030 | |
| regulation of protein modification process | GO:0031399 | 112 | 0.030 | |
| nucleoside phosphate metabolic process | GO:0006753 | 162 | 0.029 | |
| cellular component disassembly | GO:0022411 | 46 | 0.029 | |
| ncrna metabolic process | GO:0034660 | 43 | 0.029 | |
| germ cell migration | GO:0008354 | 43 | 0.028 | |
| protein complex assembly | GO:0006461 | 200 | 0.028 | |
| regulation of intracellular transport | GO:0032386 | 64 | 0.028 | |
| spermatid development | GO:0007286 | 98 | 0.028 | |
| mitotic dna integrity checkpoint | GO:0044774 | 75 | 0.027 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 130 | 0.027 | |
| protein modification process | GO:0036211 | 438 | 0.027 | |
| negative regulation of cell cycle phase transition | GO:1901988 | 103 | 0.027 | |
| chromatin silencing | GO:0006342 | 76 | 0.027 | |
| response to organic substance | GO:0010033 | 284 | 0.027 | |
| negative regulation of transcription dna templated | GO:0045892 | 237 | 0.027 | |
| regulation of rna splicing | GO:0043484 | 69 | 0.026 | |
| mrna metabolic process | GO:0016071 | 124 | 0.026 | |
| tissue morphogenesis | GO:0048729 | 297 | 0.026 | |
| response to other organism | GO:0051707 | 293 | 0.025 | |
| gene silencing by rna | GO:0031047 | 57 | 0.025 | |
| g2 dna damage checkpoint | GO:0031572 | 69 | 0.025 | |
| oocyte construction | GO:0007308 | 112 | 0.024 | |
| regulation of molecular function | GO:0065009 | 217 | 0.024 | |
| signal transduction by phosphorylation | GO:0023014 | 107 | 0.024 | |
| positive regulation of cell communication | GO:0010647 | 250 | 0.023 | |
| regulation of phosphorylation | GO:0042325 | 147 | 0.023 | |
| single organism membrane organization | GO:0044802 | 93 | 0.023 | |
| peptidyl amino acid modification | GO:0018193 | 105 | 0.022 | |
| regulation of dna recombination | GO:0000018 | 4 | 0.022 | |
| regulation of mapk cascade | GO:0043408 | 92 | 0.022 | |
| regulation of erk1 and erk2 cascade | GO:0070372 | 39 | 0.022 | |
| positive regulation of transcription factor import into nucleus | GO:0042993 | 19 | 0.022 | |
| synapse organization | GO:0050808 | 196 | 0.022 | |
| central nervous system development | GO:0007417 | 201 | 0.021 | |
| regulation of cellular localization | GO:0060341 | 136 | 0.021 | |
| multicellular organismal reproductive behavior | GO:0033057 | 110 | 0.020 | |
| chromosome separation | GO:0051304 | 42 | 0.020 | |
| cell maturation | GO:0048469 | 144 | 0.020 | |
| axon development | GO:0061564 | 297 | 0.020 | |
| protein localization | GO:0008104 | 284 | 0.019 | |
| small molecule metabolic process | GO:0044281 | 305 | 0.019 | |
| regulation of developmental growth | GO:0048638 | 174 | 0.019 | |
| regionalization | GO:0003002 | 416 | 0.019 | |
| meiotic cell cycle | GO:0051321 | 171 | 0.019 | |
| regulation of cell division | GO:0051302 | 72 | 0.019 | |
| response to bacterium | GO:0009617 | 198 | 0.019 | |
| organic substance transport | GO:0071702 | 257 | 0.018 | |
| endocytosis | GO:0006897 | 310 | 0.018 | |
| positive regulation of molecular function | GO:0044093 | 136 | 0.018 | |
| cellular protein complex disassembly | GO:0043624 | 35 | 0.018 | |
| reproductive structure development | GO:0048608 | 74 | 0.018 | |
| skin development | GO:0043588 | 65 | 0.018 | |
| chromosome segregation | GO:0007059 | 157 | 0.018 | |
| negative regulation of cell communication | GO:0010648 | 223 | 0.018 | |
| positive regulation of developmental process | GO:0051094 | 143 | 0.018 | |
| positive regulation of phosphorus metabolic process | GO:0010562 | 139 | 0.018 | |
| camera type eye development | GO:0043010 | 4 | 0.017 | |
| protein complex disassembly | GO:0043241 | 36 | 0.017 | |
| poly a mrna export from nucleus | GO:0016973 | 5 | 0.017 | |
| positive regulation of transport | GO:0051050 | 92 | 0.017 | |
| embryo development ending in birth or egg hatching | GO:0009792 | 152 | 0.016 | |
| mapk cascade | GO:0000165 | 107 | 0.016 | |
| response to alcohol | GO:0097305 | 95 | 0.016 | |
| defense response to other organism | GO:0098542 | 225 | 0.016 | |
| germ line stem cell maintenance | GO:0030718 | 50 | 0.016 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 85 | 0.016 | |
| nucleoside metabolic process | GO:0009116 | 127 | 0.016 | |
| positive regulation of signal transduction | GO:0009967 | 223 | 0.016 | |
| positive regulation of intracellular transport | GO:0032388 | 42 | 0.016 | |
| protein complex biogenesis | GO:0070271 | 201 | 0.015 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 78 | 0.015 | |
| purine ribonucleoside metabolic process | GO:0046128 | 127 | 0.015 | |
| regulation of wnt signaling pathway | GO:0030111 | 68 | 0.015 | |
| spindle stabilization | GO:0043146 | 14 | 0.014 | |
| embryonic development via the syncytial blastoderm | GO:0001700 | 148 | 0.014 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 174 | 0.014 | |
| ion transport | GO:0006811 | 145 | 0.014 | |
| spindle assembly involved in mitosis | GO:0090307 | 50 | 0.014 | |
| membrane organization | GO:0061024 | 112 | 0.014 | |
| anterior posterior pattern specification | GO:0009952 | 136 | 0.013 | |
| posttranscriptional gene silencing | GO:0016441 | 46 | 0.013 | |
| respiratory system development | GO:0060541 | 213 | 0.013 | |
| negative regulation of mitotic sister chromatid separation | GO:2000816 | 13 | 0.013 | |
| synaptic growth at neuromuscular junction | GO:0051124 | 119 | 0.013 | |
| proteasomal protein catabolic process | GO:0010498 | 59 | 0.013 | |
| positive regulation of atp catabolic process | GO:1903291 | 3 | 0.013 | |
| negative regulation of cell differentiation | GO:0045596 | 143 | 0.013 | |
| maternal determination of anterior posterior axis embryo | GO:0008358 | 74 | 0.013 | |
| extrinsic apoptotic signaling pathway | GO:0097191 | 1 | 0.013 | |
| positive regulation of erk1 and erk2 cascade | GO:0070374 | 36 | 0.013 | |
| camera type eye morphogenesis | GO:0048593 | 2 | 0.013 | |
| regulation of organelle organization | GO:0033043 | 196 | 0.013 | |
| dna integrity checkpoint | GO:0031570 | 81 | 0.012 | |
| heterocycle catabolic process | GO:0046700 | 166 | 0.012 | |
| regulation of cell differentiation | GO:0045595 | 302 | 0.012 | |
| ribose phosphate metabolic process | GO:0019693 | 145 | 0.012 | |
| chromosome organization | GO:0051276 | 360 | 0.012 | |
| negative regulation of cardioblast differentiation | GO:0051892 | 7 | 0.012 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 85 | 0.012 | |
| genitalia development | GO:0048806 | 26 | 0.011 | |
| regulation of cell development | GO:0060284 | 215 | 0.011 | |
| cellular protein modification process | GO:0006464 | 438 | 0.011 | |
| negative regulation of signaling | GO:0023057 | 219 | 0.011 | |
| positive regulation of mapk cascade | GO:0043410 | 63 | 0.011 | |
| regulation of epidermal cell differentiation | GO:0045604 | 3 | 0.011 | |
| regulation of multi organism process | GO:0043900 | 131 | 0.011 | |
| cellular response to nutrient | GO:0031670 | 1 | 0.011 | |
| regulation of sister chromatid segregation | GO:0033045 | 28 | 0.011 | |
| histone h3 k4 methylation | GO:0051568 | 16 | 0.011 | |
| positive regulation of mitotic cell cycle | GO:0045931 | 34 | 0.011 | |
| cell division | GO:0051301 | 248 | 0.011 | |
| positive regulation of multi organism process | GO:0043902 | 40 | 0.010 | |
| positive regulation of cell cycle process | GO:0090068 | 28 | 0.010 | |
| regulation of protein localization | GO:0032880 | 76 | 0.010 | |
| regulation of cellular component movement | GO:0051270 | 42 | 0.010 | |
| regulation of nuclear division | GO:0051783 | 58 | 0.010 | |
| reproductive behavior | GO:0019098 | 122 | 0.010 | |
| female gonad development | GO:0008585 | 12 | 0.010 | |
| regulation of nervous system development | GO:0051960 | 248 | 0.010 | |
| salivary gland histolysis | GO:0035070 | 88 | 0.010 | |
| nucleotide catabolic process | GO:0009166 | 109 | 0.010 | |