Drosophila melanogaster

129 known processes

knk (Dmel_CG6217)

knickkopf

(Aliases: Dmel\CG6217,Knk,gnar,Gnarled,CG6217,l(3)85Eg)

knk biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
amino sugar metabolic processGO:0006040101.000
open tracheal system developmentGO:00074242040.998
respiratory system developmentGO:00605412130.996
glucosamine containing compound metabolic processGO:190107190.992
regulation of tube length open tracheal systemGO:0035159240.990
trachea morphogenesisGO:0060439220.982
cuticle developmentGO:0042335860.978
regulation of tube architecture open tracheal systemGO:0035152680.976
chitin metabolic processGO:000603070.975
chitin based embryonic cuticle biosynthetic processGO:0008362160.966
regulation of tube size open tracheal systemGO:0035151430.961
regulation of tube diameter open tracheal systemGO:0035158110.906
branching involved in open tracheal system developmentGO:0060446450.889
regulation of tube sizeGO:0035150460.885
chitin based cuticle developmentGO:0040003490.815
trachea developmentGO:0060438290.710
terminal branching open tracheal systemGO:0007430170.708
regulation of tube diameterGO:0035296140.639
tube morphogenesisGO:00352391910.412
organonitrogen compound metabolic processGO:19015643180.386
aminoglycan biosynthetic processGO:0006023110.370
carbohydrate derivative biosynthetic processGO:1901137850.315
embryonic morphogenesisGO:00485982060.308
aminoglycan metabolic processGO:0006022180.293
regulation of anatomical structure sizeGO:00900661630.258
tube developmentGO:00352952440.236
tissue morphogenesisGO:00487292970.224
regulation of epithelial cell migration open tracheal systemGO:2000274110.224
regulation of cellular protein metabolic processGO:00322682430.209
morphogenesis of an epitheliumGO:00020092760.207
growthGO:00400073590.196
morphogenesis of a branching epitheliumGO:0061138450.171
extracellular matrix disassemblyGO:002261740.166
regulation of anatomical structure morphogenesisGO:00226032420.161
positive regulation of immune responseGO:0050778630.151
regionalizationGO:00030024160.137
regulation of multicellular organismal developmentGO:20000264140.137
dorsal trunk growth open tracheal systemGO:003500170.123
embryonic pattern specificationGO:00098801740.122
taxisGO:00423303040.119
blastoderm segmentationGO:00073501590.119
embryonic epithelial tube formationGO:000183860.116
motor neuron axon guidanceGO:0008045580.114
epithelial cell migration open tracheal systemGO:0007427320.108
imaginal disc derived appendage morphogenesisGO:00351143950.098
negative regulation of signal transductionGO:00099682060.098
carbohydrate derivative metabolic processGO:19011352170.098
molting cycle chitin based cuticleGO:0007591560.096
cell motilityGO:00488702510.094
tracheal outgrowth open tracheal systemGO:0007426180.094
negative regulation of response to stimulusGO:00485852580.092
oocyte developmentGO:00485991240.092
serotonin metabolic processGO:004242820.091
regulation of localizationGO:00328792750.088
regulation of response to woundingGO:1903034190.087
morphogenesis of a branching structureGO:0001763450.087
epithelial tube formationGO:007217570.087
imaginal disc derived appendage developmentGO:00487373990.085
localization of cellGO:00516742570.085
spiracle morphogenesis open tracheal systemGO:0035277220.083
germ cell migrationGO:0008354430.081
axon developmentGO:00615642970.080
appendage morphogenesisGO:00351073970.072
developmental growthGO:00485892800.071
embryo development ending in birth or egg hatchingGO:00097921520.070
positive regulation of macromolecule metabolic processGO:00106044050.070
embryonic hindgut morphogenesisGO:0048619480.069
single organism behaviorGO:00447083910.069
response to radiationGO:00093141550.066
post embryonic appendage morphogenesisGO:00351203850.064
posttranscriptional regulation of gene expressionGO:00106081450.063
morphogenesis of embryonic epitheliumGO:0016331940.063
thermotaxisGO:0043052160.062
positive regulation of response to stimulusGO:00485843230.061
organonitrogen compound biosynthetic processGO:19015661170.060
wing disc morphogenesisGO:00074723440.060
positive regulation of cell motilityGO:200014730.060
small molecule metabolic processGO:00442813050.058
compound eye morphogenesisGO:00017452490.057
single organism biosynthetic processGO:00447112060.056
segmentationGO:00352822070.055
response to woundingGO:0009611940.054
negative regulation of cell communicationGO:00106482230.054
anatomical structure homeostasisGO:0060249970.053
cell cell signaling involved in cell fate commitmentGO:00451682100.052
regulation of immune responseGO:00507761180.051
camera type eye developmentGO:004301040.050
negative regulation of signalingGO:00230572190.050
cellular ketone metabolic processGO:0042180240.049
malpighian tubule morphogenesisGO:0007443440.049
oxoacid metabolic processGO:00434361030.048
cell migrationGO:00164772380.047
regulation of extracellular matrix disassemblyGO:001071510.047
lipid metabolic processGO:00066291210.044
regulation of response to biotic stimulusGO:0002831630.044
body morphogenesisGO:001017120.043
positive regulation of cell migrationGO:003033520.043
establishment or maintenance of cell polarityGO:00071631670.042
regulation of molecular functionGO:00650092170.042
proteolysisGO:00065081920.041
cell migration involved in gastrulationGO:004207490.040
regulation of nervous system developmentGO:00519602480.038
appendage developmentGO:00487364010.038
positive regulation of protein metabolic processGO:00512471280.038
imaginal disc derived wing morphogenesisGO:00074763370.038
epithelial tube morphogenesisGO:0060562880.036
regulation of protein metabolic processGO:00512462560.036
ameboidal type cell migrationGO:00016671510.035
regulation of cell adhesionGO:0030155270.035
cardiac cell fate commitmentGO:0060911170.035
positive regulation of cellular amino acid metabolic processGO:004576400.034
positive regulation of cellular amine metabolic processGO:003324000.034
chemotaxisGO:00069352490.034
cellular amino acid metabolic processGO:0006520610.032
regulation of cell morphogenesisGO:00226041630.032
periodic partitioningGO:0007365290.032
amino sugar biosynthetic processGO:004634950.030
regulation of humoral immune responseGO:0002920510.030
detection of stimulusGO:00516061560.030
negative regulation of cell differentiationGO:00455961430.030
intracellular signal transductionGO:00355563000.029
regulation of embryonic developmentGO:0045995680.029
wound healingGO:0042060750.029
molting cycleGO:0042303560.029
branch fusion open tracheal systemGO:0035147170.029
negative regulation of developmental processGO:00510932010.028
response to organic substanceGO:00100332840.028
tube formationGO:0035148210.028
epithelial cell differentiationGO:00308553220.027
positive regulation of immune system processGO:0002684680.027
neurological system processGO:00508773580.027
regulation of catalytic activityGO:00507901850.027
anterior posterior pattern specificationGO:00099521360.026
protein modification processGO:00362114380.026
dorsal ventral pattern formationGO:00099531330.026
renal tubule morphogenesisGO:0061333440.026
regulation of extracellular matrix organizationGO:190305340.026
chitin based cuticle sclerotizationGO:0007593190.026
regulation of organ morphogenesisGO:2000027780.025
glial cell migrationGO:0008347310.025
hindbrain developmentGO:003090220.025
carboxylic acid metabolic processGO:0019752920.025
response to other organismGO:00517072930.025
immune response regulating signaling pathwayGO:000276420.025
chemosensory behaviorGO:00076351060.025
positive regulation of signal transductionGO:00099672230.025
defense response to other organismGO:00985422250.025
positive regulation of nitrogen compound metabolic processGO:00511733540.025
epithelial cell type specification open tracheal systemGO:0035153110.025
positive regulation of defense responseGO:0031349590.024
regulation of epithelial cell migrationGO:0010632120.024
phagocytosisGO:00069092150.024
negative regulation of notch signaling pathwayGO:0045746410.024
response to temperature stimulusGO:00092661060.024
negative regulation of cellular protein metabolic processGO:0032269850.023
regulation of defense responseGO:00313471020.023
negative regulation of protein metabolic processGO:0051248850.023
malpighian tubule developmentGO:0072002640.023
segment polarity determinationGO:0007367250.023
protein localizationGO:00081042840.023
stem cell developmentGO:0048864790.023
positive regulation of cellular protein metabolic processGO:00322701180.022
gland developmentGO:00487321910.022
renal filtration cell differentiationGO:0061318120.022
regulation of synapse structure and activityGO:00508031280.022
positive regulation of rna biosynthetic processGO:19026802660.022
stem cell differentiationGO:00488631170.022
antimicrobial humoral responseGO:0019730990.022
carbohydrate derivative catabolic processGO:19011361180.022
protein processingGO:0016485680.021
ectodermal placode morphogenesisGO:007169740.021
organic acid metabolic processGO:00060821030.021
salivary gland developmentGO:00074311620.021
positive regulation of transcription dna templatedGO:00458932660.021
larval developmentGO:00021641040.021
immune response activating signal transductionGO:000275720.021
extracellular structure organizationGO:0043062460.020
regulation of innate immune responseGO:0045088710.020
regulation of peptidase activityGO:0052547390.020
anterior posterior axis specification embryoGO:00085951030.019
regulation of multi organism processGO:00439001310.019
stem cell maintenanceGO:0019827670.019
regulation of notch signaling pathwayGO:00085931000.019
hindgut morphogenesisGO:0007442580.019
regulation of cell cell adhesionGO:0022407210.019
protein phosphorylationGO:00064681690.019
steroid catabolic processGO:000670610.019
renal tubule developmentGO:0061326640.019
cellular amide metabolic processGO:0043603800.019
protein transportGO:00150311550.019
imaginal disc growthGO:0007446370.019
immune responseGO:00069552460.019
regulation of immune system processGO:00026821760.019
regulation of locomotionGO:0040012420.019
epithelial cell migrationGO:00106311480.019
cranial nerve developmentGO:002154510.018
establishment of planar polarityGO:0001736870.018
cellular response to chemical stimulusGO:00708871990.018
connective tissue developmentGO:006144830.018
gliogenesisGO:0042063800.018
epidermis developmentGO:0008544650.018
positive regulation of cell adhesionGO:0045785100.018
indole containing compound biosynthetic processGO:004243540.018
amino sugar catabolic processGO:004634830.018
protein maturationGO:0051604710.017
regulation of cell developmentGO:00602842150.017
nephron epithelium morphogenesisGO:007208830.017
synapse assemblyGO:00074161430.017
phosphorylationGO:00163102940.017
regulation of protein modification processGO:00313991120.017
cell growthGO:00160491080.017
cellular lipid metabolic processGO:0044255830.017
activation of innate immune responseGO:000221840.017
positive regulation of phosphate metabolic processGO:00459371390.017
chromosome organizationGO:00512763600.017
vesicle mediated transportGO:00161923810.017
exocrine system developmentGO:00352721620.017
negative regulation of gene expressionGO:00106293870.017
cellular protein modification processGO:00064644380.017
regulation of neurogenesisGO:00507671580.017
axonogenesisGO:00074092900.017
imaginal disc derived leg morphogenesisGO:0007480800.017
retina development in camera type eyeGO:006004140.017
eye developmentGO:00016543230.017
developmental inductionGO:003112830.017
positive regulation of nucleic acid templated transcriptionGO:19035082660.017
regulation of establishment of planar polarityGO:0090175220.016
cellular macromolecule localizationGO:00707272200.016
cuticle pattern formationGO:0035017270.016
negative regulation of multicellular organismal processGO:00512411420.016
leg disc developmentGO:0035218920.016
secretion by cellGO:00329401010.016
dendrite morphogenesisGO:00488131990.016
olfactory behaviorGO:0042048970.016
modification dependent macromolecule catabolic processGO:0043632790.015
regulation of behaviorGO:0050795750.015
negative regulation of cell cycle processGO:00109481090.015
branching morphogenesis of an epithelial tubeGO:0048754450.015
tube fusionGO:0035146170.015
regulation of epithelial cell differentiationGO:003085640.015
kidney epithelium developmentGO:007207330.015
humoral immune responseGO:00069591170.015
response to external biotic stimulusGO:00432072930.015
macromolecule catabolic processGO:00090571610.015
negative regulation of rna metabolic processGO:00512532510.015
eye pigmentationGO:0048069430.015
mesenchymal cell differentiationGO:004876210.015
wnt signaling pathwayGO:0016055980.015
non sensory hair organizationGO:0035316470.015
salivary gland morphogenesisGO:00074351450.015
hormone metabolic processGO:0042445330.015
antimicrobial peptide productionGO:0002775460.015
cognitionGO:00508901410.015
positive regulation of peptidyl tyrosine phosphorylationGO:005073140.014
peptide metabolic processGO:0006518800.014
dendrite developmentGO:00163582040.014
regulation of proteolysisGO:0030162870.014
organic substance transportGO:00717022570.014
hormone biosynthetic processGO:0042446200.014
response to biotic stimulusGO:00096072940.014
associative learningGO:0008306650.014
aromatic amino acid family metabolic processGO:000907230.014
pole plasm assemblyGO:0007315610.014
epidermal cell differentiationGO:0009913510.014
positive regulation of molecular functionGO:00440931360.014
oocyte anterior posterior axis specificationGO:0007314720.014
signal releaseGO:0023061490.014
reproductive structure developmentGO:0048608740.014
epithelium migrationGO:00901321480.014
organic substance catabolic processGO:19015753080.014
organophosphate metabolic processGO:00196371950.014
catabolic processGO:00090564090.014
regulation of immune effector processGO:0002697520.014
genital disc developmentGO:0035215440.013
glandular epithelial cell differentiationGO:000206710.013
establishment of tissue polarityGO:0007164870.013
positive regulation of signalingGO:00230562430.013
cellular response to fibroblast growth factor stimulusGO:0044344100.013
regenerationGO:0031099160.013
urogenital system developmentGO:0001655720.013
anterior posterior axis specificationGO:00099481090.013
cell maturationGO:00484691440.013
eye morphogenesisGO:00485922600.013
endomembrane system organizationGO:00102561190.013
limb morphogenesisGO:003510810.013
intracellular transportGO:00469072280.013
central nervous system developmentGO:00074172010.013
response to bacteriumGO:00096171980.013
regulation of establishment of protein localizationGO:0070201610.013
columnar cuboidal epithelial cell developmentGO:00020662490.013
regulation of phosphate metabolic processGO:00192202100.013
axon extensionGO:0048675320.013
fibroblast growth factor receptor signaling pathwayGO:0008543100.013
establishment of protein localizationGO:00451841630.013
catechol containing compound biosynthetic processGO:000971330.013
defense response to bacteriumGO:00427421780.012
secondary branching open tracheal systemGO:000742920.012
positive regulation of innate immune responseGO:0045089380.012
negative regulation of biosynthetic processGO:00098902770.012
primary amino compound biosynthetic processGO:190116220.012
cellular component disassemblyGO:0022411460.012
regulation of cellular component biogenesisGO:00440872010.012
regulation of antimicrobial humoral responseGO:0002759500.012
cholesterol transportGO:003030120.012
response to endogenous stimulusGO:00097191190.012
neural precursor cell proliferationGO:0061351750.012
lumen formation open tracheal systemGO:0035149120.012
multicellular organismal signalingGO:0035637120.012
gonadal mesoderm developmentGO:000750680.012
digestive system developmentGO:00551231490.012
response to oxygen containing compoundGO:19017002000.012
lateral inhibitionGO:00463312060.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.012
protein catabolic processGO:00301631010.012
positive regulation of catalytic activityGO:00430851180.012
detection of abiotic stimulusGO:0009582660.011
secretionGO:00469031090.011
morphogenesis of a polarized epitheliumGO:0001738930.011
negative regulation of cell developmentGO:0010721620.011
nephron developmentGO:007200630.011
camera type eye morphogenesisGO:004859320.011
negative regulation of transcription dna templatedGO:00458922370.011
translationGO:0006412690.011
response to abiotic stimulusGO:00096283410.011
gastrulationGO:0007369700.011
striated muscle cell differentiationGO:0051146900.011
extracellular matrix organizationGO:0030198320.011
cellular response to biotic stimulusGO:007121640.011
defense response to gram negative bacteriumGO:0050829940.011
negative regulation of cellular metabolic processGO:00313243820.011
cardioblast differentiationGO:0010002200.011
skin developmentGO:0043588650.011
antimicrobial peptide biosynthetic processGO:0002777380.011
single organismal cell cell adhesionGO:0016337450.011
tissue migrationGO:00901301550.011
positive regulation of cellular biosynthetic processGO:00313283160.011
glial cell differentiationGO:0010001350.011
regulation of cellular ketone metabolic processGO:001056530.010
muscle attachmentGO:0016203360.010
cuticle pigmentationGO:0048067220.010
positive regulation of neurogenesisGO:0050769410.010
response to organic cyclic compoundGO:0014070890.010
positive regulation of production of molecular mediator of immune responseGO:0002702280.010
regulation of epithelial cell proliferationGO:005067840.010
regulation of map kinase activityGO:0043405170.010
cellular amine metabolic processGO:0044106120.010
tyrosine metabolic processGO:000657010.010
positive regulation of cell communicationGO:00106472500.010
central nervous system segmentationGO:003528350.010
regulation of cellular amino acid metabolic processGO:000652100.010
mesodermal cell fate specificationGO:000750120.010
positive regulation of phosphorus metabolic processGO:00105621390.010
regulation of neuron differentiationGO:00456641030.010

knk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
organ system cancerDOID:005068600.016
disease of cellular proliferationDOID:1456600.016
cancerDOID:16200.016
nervous system diseaseDOID:86300.015
disease of anatomical entityDOID:700.015
disease of metabolismDOID:001466700.013