| mitotic spindle organization | GO:0007052 | 220 | 0.898 | |
| cytoplasmic microtubule organization | GO:0031122 | 22 | 0.836 | |
| protein complex biogenesis | GO:0070271 | 201 | 0.736 | |
| spindle organization | GO:0007051 | 253 | 0.628 | |
| spindle assembly involved in mitosis | GO:0090307 | 50 | 0.625 | |
| organic substance transport | GO:0071702 | 257 | 0.587 | |
| vesicle mediated transport | GO:0016192 | 381 | 0.505 | Worm |
| death | GO:0016265 | 284 | 0.446 | Worm |
| protein complex assembly | GO:0006461 | 200 | 0.402 | |
| activation of cysteine type endopeptidase activity | GO:0097202 | 17 | 0.391 | |
| programmed cell death | GO:0012501 | 257 | 0.343 | Worm |
| single fertilization | GO:0007338 | 24 | 0.343 | Mouse |
| regulation of cell death | GO:0010941 | 173 | 0.331 | |
| protein transport | GO:0015031 | 155 | 0.320 | |
| negative regulation of cellular macromolecule biosynthetic process | GO:2000113 | 267 | 0.293 | |
| muscle structure development | GO:0061061 | 224 | 0.286 | |
| organelle fission | GO:0048285 | 340 | 0.279 | |
| positive regulation of developmental process | GO:0051094 | 143 | 0.276 | Worm |
| establishment of protein localization | GO:0045184 | 163 | 0.265 | |
| macromolecular complex assembly | GO:0065003 | 256 | 0.256 | |
| microtubule cytoskeleton organization involved in mitosis | GO:1902850 | 52 | 0.253 | |
| negative regulation of gene expression | GO:0010629 | 387 | 0.223 | |
| spindle assembly | GO:0051225 | 80 | 0.217 | |
| negative regulation of cellular biosynthetic process | GO:0031327 | 277 | 0.216 | |
| regulation of apoptotic process | GO:0042981 | 130 | 0.213 | |
| activation of cysteine type endopeptidase activity involved in apoptotic process | GO:0006919 | 16 | 0.206 | |
| apoptotic process | GO:0006915 | 159 | 0.196 | Worm |
| organelle assembly | GO:0070925 | 198 | 0.195 | |
| cellular macromolecule localization | GO:0070727 | 220 | 0.192 | |
| cell recognition | GO:0008037 | 102 | 0.191 | Mouse |
| cell death | GO:0008219 | 279 | 0.183 | Worm |
| cytoplasmic transport | GO:0016482 | 130 | 0.177 | |
| endocytosis | GO:0006897 | 310 | 0.164 | Worm |
| negative regulation of biosynthetic process | GO:0009890 | 277 | 0.160 | |
| negative regulation of nitrogen compound metabolic process | GO:0051172 | 265 | 0.150 | |
| intracellular transport | GO:0046907 | 228 | 0.149 | |
| mitotic nuclear division | GO:0007067 | 213 | 0.149 | |
| cellular protein complex assembly | GO:0043623 | 71 | 0.143 | Human |
| positive regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043280 | 23 | 0.130 | |
| purine ribonucleoside monophosphate metabolic process | GO:0009167 | 50 | 0.117 | |
| regulation of cell differentiation | GO:0045595 | 302 | 0.107 | |
| negative regulation of macromolecule biosynthetic process | GO:0010558 | 270 | 0.102 | |
| regulation of programmed cell death | GO:0043067 | 152 | 0.101 | |
| establishment of localization in cell | GO:0051649 | 402 | 0.101 | |
| regulation of cell development | GO:0060284 | 215 | 0.100 | |
| small molecule metabolic process | GO:0044281 | 305 | 0.092 | |
| response to peptide | GO:1901652 | 29 | 0.088 | |
| positive regulation of protein metabolic process | GO:0051247 | 128 | 0.087 | |
| response to virus | GO:0009615 | 28 | 0.084 | |
| intracellular protein transport | GO:0006886 | 104 | 0.079 | |
| cell motility | GO:0048870 | 251 | 0.079 | |
| protein localization | GO:0008104 | 284 | 0.077 | |
| fertilization | GO:0009566 | 26 | 0.076 | Mouse |
| positive regulation of cellular protein metabolic process | GO:0032270 | 118 | 0.076 | |
| regulation of proteolysis | GO:0030162 | 87 | 0.076 | |
| regulation of peptidase activity | GO:0052547 | 39 | 0.074 | |
| protein modification process | GO:0036211 | 438 | 0.072 | |
| purine containing compound metabolic process | GO:0072521 | 155 | 0.072 | |
| cellular macromolecular complex assembly | GO:0034622 | 153 | 0.068 | Human |
| regulation of protein metabolic process | GO:0051246 | 256 | 0.068 | |
| mitotic spindle elongation | GO:0000022 | 81 | 0.067 | |
| positive regulation of endopeptidase activity | GO:0010950 | 26 | 0.066 | |
| intracellular signal transduction | GO:0035556 | 300 | 0.066 | |
| positive regulation of catalytic activity | GO:0043085 | 118 | 0.064 | |
| larval development | GO:0002164 | 104 | 0.063 | Worm |
| positive regulation of peptidase activity | GO:0010952 | 29 | 0.063 | |
| multicellular organism growth | GO:0035264 | 46 | 0.061 | Worm |
| immune system process | GO:0002376 | 347 | 0.060 | |
| response to abiotic stimulus | GO:0009628 | 341 | 0.058 | |
| determination of adult lifespan | GO:0008340 | 137 | 0.056 | Worm |
| stem cell differentiation | GO:0048863 | 117 | 0.055 | |
| establishment of protein localization to organelle | GO:0072594 | 62 | 0.054 | |
| cellular amino acid metabolic process | GO:0006520 | 61 | 0.054 | |
| positive regulation of cell death | GO:0010942 | 69 | 0.054 | |
| response to biotic stimulus | GO:0009607 | 294 | 0.053 | |
| negative regulation of rna metabolic process | GO:0051253 | 251 | 0.052 | |
| nuclear division | GO:0000280 | 332 | 0.051 | |
| positive regulation of proteolysis | GO:0045862 | 52 | 0.049 | |
| organic substance catabolic process | GO:1901575 | 308 | 0.049 | |
| regulation of anatomical structure morphogenesis | GO:0022603 | 242 | 0.048 | |
| negative regulation of cellular metabolic process | GO:0031324 | 382 | 0.047 | |
| negative regulation of nucleic acid templated transcription | GO:1903507 | 240 | 0.047 | |
| proteolysis | GO:0006508 | 192 | 0.046 | |
| response to peptide hormone | GO:0043434 | 29 | 0.045 | |
| cellular protein localization | GO:0034613 | 160 | 0.045 | |
| negative regulation of nucleobase containing compound metabolic process | GO:0045934 | 261 | 0.044 | |
| negative regulation of programmed cell death | GO:0043069 | 72 | 0.044 | |
| chromatin remodeling | GO:0006338 | 72 | 0.044 | |
| positive regulation of cysteine type endopeptidase activity | GO:2001056 | 24 | 0.043 | |
| organic acid metabolic process | GO:0006082 | 103 | 0.043 | |
| single organism cellular localization | GO:1902580 | 180 | 0.043 | |
| response to organic substance | GO:0010033 | 284 | 0.042 | |
| phosphorylation | GO:0016310 | 294 | 0.042 | |
| single organism intracellular transport | GO:1902582 | 207 | 0.042 | |
| cellular protein modification process | GO:0006464 | 438 | 0.041 | |
| actin cytoskeleton organization | GO:0030036 | 206 | 0.041 | |
| response to decreased oxygen levels | GO:0036293 | 58 | 0.039 | |
| carboxylic acid metabolic process | GO:0019752 | 92 | 0.039 | |
| positive regulation of nitrogen compound metabolic process | GO:0051173 | 354 | 0.038 | |
| regulation of multicellular organism growth | GO:0040014 | 40 | 0.038 | Worm |
| chromosome organization | GO:0051276 | 360 | 0.038 | |
| regulation of multi organism process | GO:0043900 | 131 | 0.037 | |
| positive regulation of programmed cell death | GO:0043068 | 62 | 0.037 | |
| protein localization to organelle | GO:0033365 | 82 | 0.037 | |
| multicellular organismal aging | GO:0010259 | 140 | 0.037 | Worm |
| response to oxygen containing compound | GO:1901700 | 200 | 0.036 | |
| response to external biotic stimulus | GO:0043207 | 293 | 0.036 | |
| positive regulation of nucleic acid templated transcription | GO:1903508 | 266 | 0.035 | |
| negative regulation of apoptotic process | GO:0043066 | 63 | 0.035 | |
| protein localization to nucleus | GO:0034504 | 55 | 0.035 | |
| camera type eye development | GO:0043010 | 4 | 0.034 | |
| ribonucleoprotein complex biogenesis | GO:0022613 | 31 | 0.034 | |
| regulation of cellular protein metabolic process | GO:0032268 | 243 | 0.034 | |
| striated muscle cell differentiation | GO:0051146 | 90 | 0.033 | |
| protein import | GO:0017038 | 55 | 0.033 | |
| positive regulation of apoptotic process | GO:0043065 | 47 | 0.033 | |
| eye development | GO:0001654 | 323 | 0.032 | |
| negative regulation of cell differentiation | GO:0045596 | 143 | 0.032 | |
| positive regulation of molecular function | GO:0044093 | 136 | 0.031 | |
| negative regulation of cell death | GO:0060548 | 81 | 0.031 | |
| oxoacid metabolic process | GO:0043436 | 103 | 0.031 | |
| nucleoside phosphate metabolic process | GO:0006753 | 162 | 0.030 | |
| gene silencing | GO:0016458 | 138 | 0.029 | |
| sensory organ morphogenesis | GO:0090596 | 260 | 0.028 | |
| developmental growth | GO:0048589 | 280 | 0.028 | Worm |
| response to hypoxia | GO:0001666 | 53 | 0.028 | |
| body morphogenesis | GO:0010171 | 2 | 0.028 | |
| nucleoside monophosphate metabolic process | GO:0009123 | 52 | 0.027 | |
| cell division | GO:0051301 | 248 | 0.027 | |
| nuclear transport | GO:0051169 | 72 | 0.027 | |
| organonitrogen compound metabolic process | GO:1901564 | 318 | 0.027 | |
| establishment or maintenance of cell polarity | GO:0007163 | 167 | 0.027 | |
| centrosome duplication | GO:0051298 | 121 | 0.027 | |
| regulation of retinal cell programmed cell death | GO:0046668 | 18 | 0.027 | |
| positive regulation of macromolecule metabolic process | GO:0010604 | 405 | 0.027 | |
| regulation of protein transport | GO:0051223 | 57 | 0.026 | |
| glycosyl compound catabolic process | GO:1901658 | 112 | 0.026 | |
| aromatic compound catabolic process | GO:0019439 | 166 | 0.026 | |
| axonogenesis | GO:0007409 | 290 | 0.026 | |
| negative regulation of protein metabolic process | GO:0051248 | 85 | 0.026 | |
| cardiovascular system development | GO:0072358 | 82 | 0.025 | |
| response to oxygen levels | GO:0070482 | 59 | 0.025 | |
| purine ribonucleoside metabolic process | GO:0046128 | 127 | 0.025 | |
| regulation of cell cycle process | GO:0010564 | 181 | 0.025 | |
| regulation of intracellular signal transduction | GO:1902531 | 236 | 0.024 | |
| negative regulation of cell cycle process | GO:0010948 | 109 | 0.024 | |
| response to endogenous stimulus | GO:0009719 | 119 | 0.024 | |
| gland morphogenesis | GO:0022612 | 145 | 0.024 | |
| protein maturation | GO:0051604 | 71 | 0.024 | |
| regulation of proteolysis involved in cellular protein catabolic process | GO:1903050 | 44 | 0.023 | |
| negative regulation of response to stimulus | GO:0048585 | 258 | 0.023 | |
| cell proliferation | GO:0008283 | 299 | 0.023 | |
| developmental programmed cell death | GO:0010623 | 138 | 0.023 | |
| cellular response to chemical stimulus | GO:0070887 | 199 | 0.023 | |
| positive regulation of signal transduction | GO:0009967 | 223 | 0.023 | |
| macromolecule catabolic process | GO:0009057 | 161 | 0.023 | |
| positive regulation of cell migration | GO:0030335 | 2 | 0.023 | |
| cellular catabolic process | GO:0044248 | 372 | 0.022 | |
| response to bacterium | GO:0009617 | 198 | 0.022 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 119 | 0.022 | |
| response to other organism | GO:0051707 | 293 | 0.022 | |
| eye morphogenesis | GO:0048592 | 260 | 0.022 | |
| actin filament based process | GO:0030029 | 220 | 0.021 | |
| chromatin modification | GO:0016568 | 147 | 0.021 | |
| sex differentiation | GO:0007548 | 81 | 0.021 | Worm |
| gland development | GO:0048732 | 191 | 0.021 | |
| response to organonitrogen compound | GO:0010243 | 75 | 0.021 | |
| regulation of molecular function | GO:0065009 | 217 | 0.021 | |
| negative regulation of transcription dna templated | GO:0045892 | 237 | 0.021 | |
| localization of cell | GO:0051674 | 257 | 0.021 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 3 | 0.021 | |
| rna splicing via transesterification reactions | GO:0000375 | 73 | 0.021 | |
| forebrain development | GO:0030900 | 2 | 0.021 | |
| organic cyclic compound catabolic process | GO:1901361 | 168 | 0.021 | |
| single organism catabolic process | GO:0044712 | 228 | 0.021 | |
| receptor mediated endocytosis | GO:0006898 | 21 | 0.020 | Worm |
| protein phosphorylation | GO:0006468 | 169 | 0.020 | |
| response to nitrogen compound | GO:1901698 | 90 | 0.020 | |
| positive regulation of cellular biosynthetic process | GO:0031328 | 316 | 0.020 | |
| regulation of cell morphogenesis | GO:0022604 | 163 | 0.020 | |
| negative regulation of developmental process | GO:0051093 | 201 | 0.020 | |
| positive regulation of growth | GO:0045927 | 75 | 0.019 | Worm |
| axon development | GO:0061564 | 297 | 0.019 | |
| anatomical structure homeostasis | GO:0060249 | 97 | 0.019 | |
| head development | GO:0060322 | 135 | 0.019 | |
| nucleocytoplasmic transport | GO:0006913 | 72 | 0.019 | |
| positive regulation of response to stimulus | GO:0048584 | 323 | 0.019 | |
| positive regulation of cell communication | GO:0010647 | 250 | 0.019 | |
| catabolic process | GO:0009056 | 409 | 0.018 | |
| regulation of defense response | GO:0031347 | 102 | 0.018 | |
| regulation of organ morphogenesis | GO:2000027 | 78 | 0.018 | |
| muscle cell differentiation | GO:0042692 | 103 | 0.018 | |
| regulation of transport | GO:0051049 | 181 | 0.018 | |
| transcription from rna polymerase ii promoter | GO:0006366 | 368 | 0.018 | |
| regulation of cellular amine metabolic process | GO:0033238 | 3 | 0.018 | |
| positive regulation of hydrolase activity | GO:0051345 | 78 | 0.018 | |
| organophosphate catabolic process | GO:0046434 | 112 | 0.018 | |
| growth | GO:0040007 | 359 | 0.018 | Worm |
| g1 s transition of mitotic cell cycle | GO:0000082 | 31 | 0.018 | |
| positive regulation of signaling | GO:0023056 | 243 | 0.018 | |
| organonitrogen compound catabolic process | GO:1901565 | 128 | 0.018 | |
| cell cycle g1 s phase transition | GO:0044843 | 31 | 0.018 | |
| protein targeting to nucleus | GO:0044744 | 51 | 0.018 | |
| nuclear import | GO:0051170 | 51 | 0.017 | |
| protein import into nucleus | GO:0006606 | 51 | 0.017 | |
| dna replication | GO:0006260 | 48 | 0.017 | |
| positive regulation of rna biosynthetic process | GO:1902680 | 266 | 0.017 | |
| microtubule polymerization or depolymerization | GO:0031109 | 39 | 0.017 | |
| negative regulation of signal transduction | GO:0009968 | 206 | 0.017 | |
| reactive oxygen species metabolic process | GO:0072593 | 22 | 0.017 | |
| positive regulation of multicellular organismal process | GO:0051240 | 143 | 0.017 | Worm |
| urogenital system development | GO:0001655 | 72 | 0.017 | |
| negative regulation of multicellular organismal process | GO:0051241 | 142 | 0.016 | |
| protein destabilization | GO:0031648 | 2 | 0.016 | |
| negative regulation of signaling | GO:0023057 | 219 | 0.016 | |
| embryonic morphogenesis | GO:0048598 | 206 | 0.016 | |
| zymogen activation | GO:0031638 | 20 | 0.016 | |
| ribonucleoside metabolic process | GO:0009119 | 127 | 0.016 | |
| negative regulation of cell development | GO:0010721 | 62 | 0.016 | |
| regulation of phosphate metabolic process | GO:0019220 | 210 | 0.016 | |
| regulation of phosphorus metabolic process | GO:0051174 | 210 | 0.016 | |
| regulation of hydrolase activity | GO:0051336 | 97 | 0.016 | |
| retinal cell programmed cell death | GO:0046666 | 25 | 0.016 | |
| cellular response to dna damage stimulus | GO:0006974 | 223 | 0.015 | |
| regulation of protein localization | GO:0032880 | 76 | 0.015 | |
| positive regulation of cellular component organization | GO:0051130 | 156 | 0.015 | |
| taxis | GO:0042330 | 304 | 0.015 | |
| regulation of catalytic activity | GO:0050790 | 185 | 0.015 | |
| regulation of cellular protein catabolic process | GO:1903362 | 44 | 0.015 | |
| response to lipopolysaccharide | GO:0032496 | 4 | 0.015 | |
| epithelial cell differentiation | GO:0030855 | 322 | 0.015 | |
| protein processing | GO:0016485 | 68 | 0.015 | |
| actin filament organization | GO:0007015 | 126 | 0.015 | |
| purine ribonucleotide catabolic process | GO:0009154 | 109 | 0.015 | |
| developmental pigmentation | GO:0048066 | 68 | 0.014 | |
| cell type specific apoptotic process | GO:0097285 | 38 | 0.014 | |
| protein catabolic process | GO:0030163 | 101 | 0.014 | |
| phagocytosis | GO:0006909 | 215 | 0.014 | |
| regulation of meiosis | GO:0040020 | 3 | 0.014 | |
| positive regulation of macromolecule biosynthetic process | GO:0010557 | 283 | 0.014 | |
| muscle organ development | GO:0007517 | 127 | 0.014 | |
| embryo development ending in birth or egg hatching | GO:0009792 | 152 | 0.014 | Worm |
| positive regulation of gene expression | GO:0010628 | 290 | 0.014 | |
| cellular response to extracellular stimulus | GO:0031668 | 64 | 0.014 | |
| negative regulation of rna biosynthetic process | GO:1902679 | 240 | 0.014 | |
| purine nucleotide catabolic process | GO:0006195 | 109 | 0.014 | |
| cell cycle phase transition | GO:0044770 | 140 | 0.014 | |
| connective tissue development | GO:0061448 | 3 | 0.014 | |
| microtubule organizing center organization | GO:0031023 | 168 | 0.013 | |
| stem cell development | GO:0048864 | 79 | 0.013 | |
| protein targeting | GO:0006605 | 64 | 0.013 | |
| immune effector process | GO:0002252 | 98 | 0.013 | |
| response to alcohol | GO:0097305 | 95 | 0.013 | |
| heterocycle catabolic process | GO:0046700 | 166 | 0.013 | |
| negative regulation of cell cycle | GO:0045786 | 116 | 0.013 | |
| regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043281 | 25 | 0.013 | |
| cellular response to organic substance | GO:0071310 | 132 | 0.012 | |
| dna metabolic process | GO:0006259 | 227 | 0.012 | |
| reproductive structure development | GO:0048608 | 74 | 0.012 | Worm |
| defense response | GO:0006952 | 300 | 0.012 | |
| regulation of cellular component biogenesis | GO:0044087 | 201 | 0.012 | |
| regulation of multicellular organismal development | GO:2000026 | 414 | 0.012 | |
| positive regulation of nucleobase containing compound metabolic process | GO:0045935 | 332 | 0.012 | |
| regulation of cellular localization | GO:0060341 | 136 | 0.012 | |
| purine nucleoside metabolic process | GO:0042278 | 127 | 0.012 | |
| cell projection assembly | GO:0030031 | 94 | 0.012 | |
| chromatin organization | GO:0006325 | 207 | 0.012 | |
| dendrite morphogenesis | GO:0048813 | 199 | 0.012 | |
| kidney development | GO:0001822 | 3 | 0.011 | |
| nucleoside catabolic process | GO:0009164 | 112 | 0.011 | |
| positive regulation of organelle organization | GO:0010638 | 65 | 0.011 | |
| purine ribonucleotide metabolic process | GO:0009150 | 145 | 0.011 | |
| cellular response to hormone stimulus | GO:0032870 | 44 | 0.011 | |
| regulation of catabolic process | GO:0009894 | 170 | 0.011 | |
| negative regulation of protein processing | GO:0010955 | 31 | 0.011 | |
| purine nucleotide metabolic process | GO:0006163 | 146 | 0.011 | |
| cell migration | GO:0016477 | 238 | 0.011 | |
| single organism behavior | GO:0044708 | 391 | 0.011 | |
| negative regulation of cell communication | GO:0010648 | 223 | 0.011 | |
| genitalia development | GO:0048806 | 26 | 0.011 | Worm |
| embryonic organ development | GO:0048568 | 50 | 0.011 | |
| developmental maturation | GO:0021700 | 172 | 0.011 | |
| cellular ketone metabolic process | GO:0042180 | 24 | 0.011 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 0 | 0.011 | |
| mitotic cell cycle phase transition | GO:0044772 | 138 | 0.011 | |
| regulation of endopeptidase activity | GO:0052548 | 36 | 0.010 | |
| positive regulation of transcription dna templated | GO:0045893 | 266 | 0.010 | |
| amine metabolic process | GO:0009308 | 12 | 0.010 | |
| regulation of cell shape | GO:0008360 | 113 | 0.010 | |
| purine ribonucleoside catabolic process | GO:0046130 | 112 | 0.010 | |
| positive regulation of multicellular organism growth | GO:0040018 | 21 | 0.010 | Worm |
| hematopoietic or lymphoid organ development | GO:0048534 | 57 | 0.010 | |
| cellular response to oxygen containing compound | GO:1901701 | 79 | 0.010 | |
| response to hormone | GO:0009725 | 45 | 0.010 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 165 | 0.010 | |
| regulation of localization | GO:0032879 | 275 | 0.010 | |
| positive regulation of cell differentiation | GO:0045597 | 64 | 0.010 | |