IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

Rab2 (Dmel_CG3269)

Rab-protein 2

(Aliases: DRAB2,rab2,CG3269,Drab2,DmRab2,Dmel\CG3269,DRab2)

Entrez: 35577
FLYBASE: FBgn0014009
UniProtKB: O18333

Process Predictions
Disease Predictions

Rab2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
defense response to fungus	GO:0050832	48	0.949
regulation of ph	GO:0006885	7	0.940	Fly
response to fungus	GO:0009620	50	0.796
defense response to other organism	GO:0098542	225	0.713	Fly
vesicle mediated transport	GO:0016192	381	0.577	Fly
ph reduction	GO:0045851	7	0.558	Fly
endosomal transport	GO:0016197	44	0.530
monovalent inorganic cation homeostasis	GO:0055067	7	0.528	Fly
nucleoside triphosphate metabolic process	GO:0009141	120	0.521	Human
defense response	GO:0006952	300	0.498	Fly
phagolysosome assembly	GO:0001845	2	0.466	Fly
single organism intracellular transport	GO:1902582	207	0.454
small molecule metabolic process	GO:0044281	305	0.449	Human
eye development	GO:0001654	323	0.383
nucleotide catabolic process	GO:0009166	109	0.369	Human
nucleoside triphosphate catabolic process	GO:0009143	108	0.358	Human
nucleoside metabolic process	GO:0009116	127	0.336	Human
post golgi vesicle mediated transport	GO:0006892	11	0.334
regulation of cellular ph	GO:0030641	7	0.298	Fly
gtp metabolic process	GO:0046039	72	0.296	Human
homeostatic process	GO:0042592	199	0.288	Fly
regulation of multi organism process	GO:0043900	131	0.283
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.282	Human
golgi vesicle transport	GO:0048193	27	0.278
establishment of localization in cell	GO:0051649	402	0.269
purine nucleotide catabolic process	GO:0006195	109	0.261	Human
chromosome segregation	GO:0007059	157	0.260
response to other organism	GO:0051707	293	0.242	Fly
endocytosis	GO:0006897	310	0.228	Fly
axon guidance	GO:0007411	233	0.225
cellular ion homeostasis	GO:0006873	39	0.216	Fly
purine ribonucleoside metabolic process	GO:0046128	127	0.215	Human
appendage morphogenesis	GO:0035107	397	0.203
carbohydrate derivative catabolic process	GO:1901136	118	0.202	Human
positive regulation of biosynthetic process	GO:0009891	316	0.196
imaginal disc fusion	GO:0046528	19	0.196
purine ribonucleotide catabolic process	GO:0009154	109	0.194	Human
ribose phosphate metabolic process	GO:0019693	145	0.194	Human
asymmetric protein localization	GO:0008105	33	0.193
imaginal disc derived appendage development	GO:0048737	399	0.188
single organism cellular localization	GO:1902580	180	0.186
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.185	Human
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.184
purine nucleoside metabolic process	GO:0042278	127	0.183	Human
regulation of cell morphogenesis	GO:0022604	163	0.176
cytoplasmic transport	GO:0016482	130	0.173
carbohydrate derivative metabolic process	GO:1901135	217	0.167	Human
axon development	GO:0061564	297	0.165
glycosyl compound catabolic process	GO:1901658	112	0.161	Human
nucleobase containing compound catabolic process	GO:0034655	165	0.161	Human
ribonucleotide metabolic process	GO:0009259	145	0.159	Human
aromatic compound catabolic process	GO:0019439	166	0.159	Human
intracellular ph reduction	GO:0051452	7	0.155	Fly
response to organic substance	GO:0010033	284	0.155
ion homeostasis	GO:0050801	55	0.152	Fly
pole plasm assembly	GO:0007315	61	0.151
protein modification process	GO:0036211	438	0.149
appendage development	GO:0048736	401	0.146
immune system process	GO:0002376	347	0.146
regulation of cell shape	GO:0008360	113	0.145
cell motility	GO:0048870	251	0.145
organic cyclic compound catabolic process	GO:1901361	168	0.142	Human
axonogenesis	GO:0007409	290	0.139
purine ribonucleotide metabolic process	GO:0009150	145	0.137	Human
positive regulation of rna metabolic process	GO:0051254	271	0.136
transmembrane receptor protein serine threonine kinase signaling pathway	GO:0007178	65	0.135
eye morphogenesis	GO:0048592	260	0.135
photoreceptor cell development	GO:0042461	96	0.135
small gtpase mediated signal transduction	GO:0007264	88	0.133
guanosine containing compound catabolic process	GO:1901069	74	0.132	Human
secretion	GO:0046903	109	0.132
nucleoside catabolic process	GO:0009164	112	0.129	Human
post embryonic appendage morphogenesis	GO:0035120	385	0.129
regionalization	GO:0003002	416	0.129
actin filament based process	GO:0030029	220	0.128
phagocytosis	GO:0006909	215	0.127	Fly
nucleobase containing small molecule metabolic process	GO:0055086	174	0.126	Human
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.125	Human
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.125
ribonucleoside catabolic process	GO:0042454	112	0.123	Human
body morphogenesis	GO:0010171	2	0.121
chemotaxis	GO:0006935	249	0.121
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.119
positive regulation of rna biosynthetic process	GO:1902680	266	0.117
regulation of macroautophagy	GO:0016241	15	0.116
tissue morphogenesis	GO:0048729	297	0.116
heterocycle catabolic process	GO:0046700	166	0.116	Human
purine nucleoside catabolic process	GO:0006152	112	0.114	Human
adult chitin containing cuticle pigmentation	GO:0048085	16	0.112
positive regulation of gene expression	GO:0010628	290	0.112
nuclear division	GO:0000280	332	0.111
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.111
organonitrogen compound catabolic process	GO:1901565	128	0.109	Human
imaginal disc fusion thorax closure	GO:0046529	19	0.106
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.106	Human
vesicle organization	GO:0016050	44	0.104	Fly
oocyte construction	GO:0007308	112	0.102
compound eye morphogenesis	GO:0001745	249	0.099
leg disc development	GO:0035218	92	0.098
actin filament organization	GO:0007015	126	0.098
glycosyl compound metabolic process	GO:1901657	127	0.097	Human
regulation of autophagy	GO:0010506	62	0.097
compound eye development	GO:0048749	307	0.096
endosome to lysosome transport	GO:0008333	7	0.095
cellular catabolic process	GO:0044248	372	0.095	Human
oocyte axis specification	GO:0007309	108	0.095
pole plasm mrna localization	GO:0019094	49	0.094
regulation of anatomical structure morphogenesis	GO:0022603	242	0.094
positive regulation of transcription dna templated	GO:0045893	266	0.094
sensory organ morphogenesis	GO:0090596	260	0.093
intracellular transport	GO:0046907	228	0.092
intracellular protein transport	GO:0006886	104	0.091
organophosphate catabolic process	GO:0046434	112	0.091	Human
morphogenesis of an epithelium	GO:0002009	276	0.090
fibroblast growth factor receptor signaling pathway	GO:0008543	10	0.090
ras protein signal transduction	GO:0007265	88	0.088
regulation of multicellular organismal development	GO:2000026	414	0.088
nucleoside phosphate catabolic process	GO:1901292	110	0.088	Human
purine nucleotide metabolic process	GO:0006163	146	0.086	Human
organelle assembly	GO:0070925	198	0.085	Fly
cellular chemical homeostasis	GO:0055082	40	0.082	Fly
lysosome organization	GO:0007040	4	0.079	Fly
segmentation	GO:0035282	207	0.079
regulation of synapse structure and activity	GO:0050803	128	0.078
photoreceptor cell differentiation	GO:0046530	170	0.077
death	GO:0016265	284	0.076
cellular nitrogen compound catabolic process	GO:0044270	165	0.074	Human
regulation of synapse organization	GO:0050807	110	0.074
innate immune response	GO:0045087	144	0.073
cellular response to organic substance	GO:0071310	132	0.073
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.073	Human
maternal determination of anterior posterior axis embryo	GO:0008358	74	0.072
regulation of localization	GO:0032879	275	0.072
gtp catabolic process	GO:0006184	72	0.070	Human
organic substance catabolic process	GO:1901575	308	0.068	Human
spinal cord dorsal ventral patterning	GO:0021513	1	0.068
embryonic pattern specification	GO:0009880	174	0.068
response to external biotic stimulus	GO:0043207	293	0.067	Fly
regulation of catabolic process	GO:0009894	170	0.066
guanosine containing compound metabolic process	GO:1901068	74	0.065	Human
oocyte development	GO:0048599	124	0.064
neuron projection guidance	GO:0097485	241	0.064
organonitrogen compound metabolic process	GO:1901564	318	0.064	Human
regulation of chitin based cuticle tanning	GO:0007564	14	0.063
border follicle cell migration	GO:0007298	113	0.062
regulation of protein localization	GO:0032880	76	0.062
protein localization	GO:0008104	284	0.062
tube development	GO:0035295	244	0.062
chemical homeostasis	GO:0048878	92	0.062	Fly
cell death	GO:0008219	279	0.062
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.060	Human
imaginal disc derived wing morphogenesis	GO:0007476	337	0.060
oocyte anterior posterior axis specification	GO:0007314	72	0.060
cellular response to chemical stimulus	GO:0070887	199	0.058
vacuole organization	GO:0007033	8	0.057	Fly
positive regulation of cellular biosynthetic process	GO:0031328	316	0.056
actin cytoskeleton organization	GO:0030036	206	0.056
cell adhesion	GO:0007155	136	0.056
oocyte differentiation	GO:0009994	145	0.056
axis specification	GO:0009798	167	0.055
regulation of anatomical structure size	GO:0090066	163	0.055
cellular response to extracellular stimulus	GO:0031668	64	0.054
purine containing compound metabolic process	GO:0072521	155	0.054	Human
intracellular signal transduction	GO:0035556	300	0.054
regulation of vesicle mediated transport	GO:0060627	59	0.053
regulation of intracellular ph	GO:0051453	7	0.053	Fly
epithelial cell differentiation	GO:0030855	322	0.053
negative regulation of cellular biosynthetic process	GO:0031327	277	0.052
early endosome to late endosome transport	GO:0045022	3	0.052
embryonic axis specification	GO:0000578	107	0.052
programmed cell death	GO:0012501	257	0.052
cellular protein modification process	GO:0006464	438	0.052
anterior posterior axis specification embryo	GO:0008595	103	0.052
cation homeostasis	GO:0055080	51	0.051	Fly
ovarian follicle cell development	GO:0030707	248	0.051
epithelium migration	GO:0090132	148	0.051
purine containing compound catabolic process	GO:0072523	112	0.049	Human
autophagic vacuole assembly	GO:0000045	2	0.049
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.049
dorsal ventral pattern formation	GO:0009953	133	0.049
negative regulation of transcription dna templated	GO:0045892	237	0.048
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.048
negative regulation of gene expression	GO:0010629	387	0.047
regulation of ras protein signal transduction	GO:0046578	93	0.047
secretion by cell	GO:0032940	101	0.046
cell migration	GO:0016477	238	0.046
imaginal disc derived leg morphogenesis	GO:0007480	80	0.045
response to growth factor	GO:0070848	31	0.045
response to oxygen containing compound	GO:1901700	200	0.045
purine ribonucleoside catabolic process	GO:0046130	112	0.045	Human
ribonucleotide catabolic process	GO:0009261	109	0.044	Human
transcription from rna polymerase ii promoter	GO:0006366	368	0.044
regulation of nervous system development	GO:0051960	248	0.044
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.044
somatic muscle development	GO:0007525	66	0.043
regulation of embryonic cell shape	GO:0016476	30	0.043
molting cycle	GO:0042303	56	0.043
developmental growth	GO:0048589	280	0.043
regulation of cellular component biogenesis	GO:0044087	201	0.042
endocytic recycling	GO:0032456	13	0.042
actin cytoskeleton reorganization	GO:0031532	22	0.042
wing disc morphogenesis	GO:0007472	344	0.042
positive regulation of secretion	GO:0051047	22	0.041
cellular cation homeostasis	GO:0030003	38	0.041	Fly
ovarian follicle cell migration	GO:0007297	121	0.041
nucleoside phosphate metabolic process	GO:0006753	162	0.040	Human
tripartite regional subdivision	GO:0007351	103	0.040
response to nutrient levels	GO:0031667	114	0.040
regulation of cytoskeleton organization	GO:0051493	89	0.040
establishment or maintenance of cell polarity	GO:0007163	167	0.040
localization of cell	GO:0051674	257	0.039
negative regulation of cellular metabolic process	GO:0031324	382	0.039
germarium derived egg chamber formation	GO:0007293	101	0.039
cytoplasm organization	GO:0007028	64	0.039
pigmentation	GO:0043473	75	0.038
catabolic process	GO:0009056	409	0.038	Human
spindle organization	GO:0007051	253	0.037
phosphorylation	GO:0016310	294	0.037
cuticle development	GO:0042335	86	0.037
regulation of intracellular signal transduction	GO:1902531	236	0.036
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.036
regulation of developmental pigmentation	GO:0048070	24	0.036
regulation of adult chitin containing cuticle pigmentation	GO:0048082	13	0.036
taxis	GO:0042330	304	0.036
response to biotic stimulus	GO:0009607	294	0.036	Fly
developmental pigmentation	GO:0048066	68	0.036
single organism catabolic process	GO:0044712	228	0.035	Human
regulation of cellular component size	GO:0032535	98	0.035
compound eye photoreceptor development	GO:0042051	78	0.034
protein modification by small protein conjugation	GO:0032446	79	0.034
regulation of phosphate metabolic process	GO:0019220	210	0.034
cellular homeostasis	GO:0019725	80	0.034	Fly
embryonic development via the syncytial blastoderm	GO:0001700	148	0.034
neurological system process	GO:0050877	358	0.033
meiotic nuclear division	GO:0007126	151	0.033
regulation of gene expression epigenetic	GO:0040029	128	0.033
epithelial cell migration	GO:0010631	148	0.032
cellular response to endogenous stimulus	GO:0071495	80	0.032
positive regulation of cellular catabolic process	GO:0031331	95	0.032
epithelial cell development	GO:0002064	274	0.032
oocyte microtubule cytoskeleton organization	GO:0016325	35	0.032
anterior posterior axis specification	GO:0009948	109	0.032
regulation of cell death	GO:0010941	173	0.032
proteolysis	GO:0006508	192	0.032
macromolecule catabolic process	GO:0009057	161	0.032
dorsal closure	GO:0007391	79	0.031
cuticle pigmentation	GO:0048067	22	0.031
response to oxidative stress	GO:0006979	86	0.031
developmental maturation	GO:0021700	172	0.031
positive regulation of cellular component organization	GO:0051130	156	0.031
negative regulation of rna biosynthetic process	GO:1902679	240	0.031
positive regulation of molecular function	GO:0044093	136	0.031
leg disc morphogenesis	GO:0007478	80	0.031
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.030
male courtship behavior	GO:0008049	63	0.030
eye antennal disc development	GO:0035214	60	0.030
organophosphate metabolic process	GO:0019637	195	0.030	Human
regulation of cytoplasmic transport	GO:1903649	47	0.030
female meiosis chromosome segregation	GO:0016321	33	0.030
cellular macromolecular complex assembly	GO:0034622	153	0.030
immune response	GO:0006955	246	0.030
single organism membrane budding	GO:1902591	2	0.030
oocyte dorsal ventral axis specification	GO:0007310	34	0.029
blastoderm segmentation	GO:0007350	159	0.029
positive regulation of phosphate metabolic process	GO:0045937	139	0.029
centrosome duplication	GO:0051298	121	0.029
centrosome cycle	GO:0007098	137	0.028
synaptic growth at neuromuscular junction	GO:0051124	119	0.028
regulation of cell differentiation	GO:0045595	302	0.028
embryonic morphogenesis	GO:0048598	206	0.028
organelle fission	GO:0048285	340	0.027
lamellipodium organization	GO:0097581	21	0.027
negative regulation of cell communication	GO:0010648	223	0.027
response to extracellular stimulus	GO:0009991	116	0.027
stem cell proliferation	GO:0072089	88	0.027
leucine import	GO:0060356	3	0.027
regulation of cell cycle	GO:0051726	291	0.027
cellular macromolecule localization	GO:0070727	220	0.027
organic substance transport	GO:0071702	257	0.027
positive regulation of response to stimulus	GO:0048584	323	0.027
defense response to bacterium	GO:0042742	178	0.027	Fly
cell proliferation	GO:0008283	299	0.027
positive regulation of cell size	GO:0045793	21	0.026
columnar cuboidal epithelial cell development	GO:0002066	249	0.026
protein localization to golgi apparatus	GO:0034067	3	0.026
regulation of lamellipodium organization	GO:1902743	15	0.026
mating behavior	GO:0007617	106	0.026
immune response regulating signaling pathway	GO:0002764	2	0.026
cellular response to growth factor stimulus	GO:0071363	30	0.026
retrograde transport endosome to golgi	GO:0042147	3	0.026
establishment or maintenance of microtubule cytoskeleton polarity	GO:0030951	41	0.026
multicellular organismal aging	GO:0010259	140	0.025
chorion containing eggshell pattern formation	GO:0030381	11	0.025
intracellular mrna localization involved in anterior posterior axis specification	GO:0060811	53	0.025
organelle localization	GO:0051640	148	0.025
actin filament bundle assembly	GO:0051017	26	0.025
regulation of neuron projection development	GO:0010975	69	0.025
connective tissue development	GO:0061448	3	0.025
intracellular mrna localization	GO:0008298	66	0.025
synapse organization	GO:0050808	196	0.025
regulation of developmental growth	GO:0048638	174	0.024
gastrulation with mouth forming first	GO:0001703	36	0.024
protein targeting	GO:0006605	64	0.024
egg activation	GO:0007343	9	0.024
cellular protein localization	GO:0034613	160	0.024
regulation of immune effector process	GO:0002697	52	0.023
maintenance of location	GO:0051235	73	0.023
eye photoreceptor cell differentiation	GO:0001754	145	0.023
circadian behavior	GO:0048512	76	0.023
anterior posterior pattern specification	GO:0009952	136	0.023
gastrulation	GO:0007369	70	0.023
regulation of purine nucleotide catabolic process	GO:0033121	48	0.023
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.023
tricarboxylic acid metabolic process	GO:0072350	1	0.023
peptidyl proline hydroxylation	GO:0019511	1	0.022
eggshell chorion assembly	GO:0007306	66	0.022
regulation of microtubule cytoskeleton organization	GO:0070507	41	0.022
fertilization	GO:0009566	26	0.022
positive regulation of exocytosis	GO:0045921	4	0.022
ion transport	GO:0006811	145	0.022
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.022
imaginal disc pattern formation	GO:0007447	91	0.022
growth	GO:0040007	359	0.022
immune effector process	GO:0002252	98	0.022
response to glucose	GO:0009749	2	0.022
regulation of cellular localization	GO:0060341	136	0.022
negative regulation of response to stimulus	GO:0048585	258	0.022
protein catabolic process	GO:0030163	101	0.021
protein transmembrane transport	GO:0071806	4	0.021
negative regulation of signal transduction	GO:0009968	206	0.021
regulation of intracellular protein transport	GO:0033157	46	0.021
secondary metabolic process	GO:0019748	75	0.020
pattern recognition receptor signaling pathway	GO:0002221	2	0.020
interspecies interaction between organisms	GO:0044419	16	0.020
meiotic cell cycle	GO:0051321	171	0.020
negative regulation of smoothened signaling pathway	GO:0045879	16	0.020
membrane organization	GO:0061024	112	0.020
negative regulation of response to external stimulus	GO:0032102	22	0.020
retina development in camera type eye	GO:0060041	4	0.020
autophagy	GO:0006914	108	0.020
ribonucleoside metabolic process	GO:0009119	127	0.020	Human
regulation of actin cytoskeleton organization	GO:0032956	42	0.020
positive regulation of developmental process	GO:0051094	143	0.019
mitotic nuclear division	GO:0007067	213	0.019
cellular response to dna damage stimulus	GO:0006974	223	0.019
centriole replication	GO:0007099	24	0.019
digestive tract morphogenesis	GO:0048546	127	0.019
intracellular mrna localization involved in pattern specification process	GO:0060810	56	0.019
positive regulation of phosphorus metabolic process	GO:0010562	139	0.019
ameboidal type cell migration	GO:0001667	151	0.019
torc1 signaling	GO:0038202	12	0.019
cell growth	GO:0016049	108	0.019
cell division	GO:0051301	248	0.019
developmental programmed cell death	GO:0010623	138	0.019
regulation of cellular catabolic process	GO:0031329	157	0.019
protein targeting to nucleus	GO:0044744	51	0.019
striated muscle cell differentiation	GO:0051146	90	0.019
response to starvation	GO:0042594	97	0.019
spinal cord development	GO:0021510	1	0.018
rna processing	GO:0006396	147	0.018
regulation of organelle organization	GO:0033043	196	0.018
regulation of cell cycle process	GO:0010564	181	0.018
gastrulation involving germ band extension	GO:0010004	36	0.018
muscle cell differentiation	GO:0042692	103	0.018
protein localization to organelle	GO:0033365	82	0.018
positive regulation of cell migration	GO:0030335	2	0.018
digestive system development	GO:0055123	149	0.018
rna localization	GO:0006403	115	0.018
hematopoietic or lymphoid organ development	GO:0048534	57	0.018
establishment or maintenance of apical basal cell polarity	GO:0035088	34	0.018
rho protein signal transduction	GO:0007266	14	0.018
negative regulation of signaling	GO:0023057	219	0.018
determination of dorsal ventral asymmetry	GO:0048262	3	0.018
establishment or maintenance of epithelial cell apical basal polarity	GO:0045197	24	0.018
response to temperature stimulus	GO:0009266	106	0.017
histolysis	GO:0007559	102	0.017
negative regulation of cellular component organization	GO:0051129	108	0.017
aging	GO:0007568	143	0.017
macromolecular complex assembly	GO:0065003	256	0.017
vesicle localization	GO:0051648	55	0.017
cellular response to fibroblast growth factor stimulus	GO:0044344	10	0.017
negative regulation of rna metabolic process	GO:0051253	251	0.017
establishment of protein localization to organelle	GO:0072594	62	0.017
cognition	GO:0050890	141	0.017
atp metabolic process	GO:0046034	49	0.017
sensory perception	GO:0007600	196	0.017
regulation of synaptic transmission	GO:0050804	69	0.017
pole plasm rna localization	GO:0007316	52	0.017
determination of adult lifespan	GO:0008340	137	0.017
regulation of response to oxidative stress	GO:1902882	4	0.017
regulation of transport	GO:0051049	181	0.017
establishment of planar polarity	GO:0001736	87	0.017
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.017
cellular protein catabolic process	GO:0044257	83	0.017
purine nucleoside monophosphate metabolic process	GO:0009126	50	0.016
regulation of programmed cell death	GO:0043067	152	0.016
regulation of innate immune response	GO:0045088	71	0.016
wing disc pattern formation	GO:0035222	66	0.016
organelle fusion	GO:0048284	46	0.016
melanization defense response	GO:0035006	45	0.016
nuclear dna replication	GO:0033260	1	0.016
nucleoside monophosphate metabolic process	GO:0009123	52	0.016
chemosensory behavior	GO:0007635	106	0.016
glutamate secretion	GO:0014047	1	0.016
growth of symbiont involved in interaction with host	GO:0044116	9	0.016
regulation of response to external stimulus	GO:0032101	115	0.016
positive regulation of macromolecule metabolic process	GO:0010604	405	0.016
biological adhesion	GO:0022610	138	0.016
pole plasm oskar mrna localization	GO:0045451	46	0.016
oocyte fate determination	GO:0030716	27	0.016
lipid storage	GO:0019915	38	0.015
microtubule organizing center organization	GO:0031023	168	0.015
rhabdomere development	GO:0042052	38	0.015
actin polymerization or depolymerization	GO:0008154	31	0.015
positive regulation of signaling	GO:0023056	243	0.015
regulation of molecular function	GO:0065009	217	0.015
nucleoside monophosphate catabolic process	GO:0009125	39	0.015
positive regulation of autophagy	GO:0010508	21	0.015
metal ion homeostasis	GO:0055065	44	0.015
positive regulation of catabolic process	GO:0009896	105	0.015
regulation of response to biotic stimulus	GO:0002831	63	0.015
cell fate determination	GO:0001709	91	0.015
cell maturation	GO:0048469	144	0.015
single organism membrane organization	GO:0044802	93	0.015
negative regulation of nervous system development	GO:0051961	92	0.015
regulation of secretion by cell	GO:1903530	39	0.015
cell cycle checkpoint	GO:0000075	95	0.015
regulation of body fluid levels	GO:0050878	14	0.015
immune system development	GO:0002520	57	0.015
morphogenesis of embryonic epithelium	GO:0016331	94	0.015
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.015
neuron recognition	GO:0008038	101	0.015
oocyte nucleus localization involved in oocyte dorsal ventral axis specification	GO:0051663	12	0.014
cellular response to nutrient levels	GO:0031669	62	0.014
dorsal ventral pattern formation imaginal disc	GO:0007450	51	0.014
protein complex assembly	GO:0006461	200	0.014
establishment or maintenance of cytoskeleton polarity	GO:0030952	44	0.014
establishment or maintenance of bipolar cell polarity	GO:0061245	34	0.014
spinal cord patterning	GO:0021511	1	0.014
purine ribonucleoside monophosphate metabolic process	GO:0009167	50	0.014
regulation of protein import into nucleus	GO:0042306	28	0.014
positive regulation of multicellular organismal process	GO:0051240	143	0.014
regulation of microtubule based process	GO:0032886	49	0.014
negative regulation of growth of symbiont involved in interaction with host	GO:0044146	9	0.014
very long chain fatty acid catabolic process	GO:0042760	2	0.014
tissue migration	GO:0090130	155	0.014
pigment biosynthetic process	GO:0046148	36	0.014
regulation of intracellular transport	GO:0032386	64	0.014
arp2 3 complex mediated actin nucleation	GO:0034314	3	0.014
protein transport	GO:0015031	155	0.014
multi organism behavior	GO:0051705	175	0.014
regulation of nucleoside metabolic process	GO:0009118	50	0.014
oxoacid metabolic process	GO:0043436	103	0.014
single organism carbohydrate metabolic process	GO:0044723	72	0.014
ribonucleoside monophosphate catabolic process	GO:0009158	39	0.014
positive regulation of gtp catabolic process	GO:0033126	43	0.014
salivary gland histolysis	GO:0035070	88	0.014
dorsal ventral axis specification	GO:0009950	66	0.014
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.014
cytokinesis	GO:0000910	90	0.014
positive regulation of cell motility	GO:2000147	3	0.014
genital disc development	GO:0035215	44	0.013
gland development	GO:0048732	191	0.013
regulation of catalytic activity	GO:0050790	185	0.013
regulation of reproductive process	GO:2000241	54	0.013
establishment of tissue polarity	GO:0007164	87	0.013
regulation of cellular response to oxidative stress	GO:1900407	4	0.013
endomembrane system organization	GO:0010256	119	0.013	Human
protein polymerization	GO:0051258	42	0.013
rhythmic behavior	GO:0007622	76	0.013
septate junction assembly	GO:0019991	26	0.013
protein k48 linked ubiquitination	GO:0070936	3	0.013
apoptotic process	GO:0006915	159	0.013
membrane budding	GO:0006900	4	0.013
dorsal closure spreading of leading edge cells	GO:0007395	4	0.013
positive regulation of intracellular signal transduction	GO:1902533	116	0.013
regulation of immune system process	GO:0002682	176	0.013
positive regulation of protein complex assembly	GO:0031334	22	0.013
posttranscriptional regulation of gene expression	GO:0010608	145	0.013
mitochondrion organization	GO:0007005	65	0.013
nucleocytoplasmic transport	GO:0006913	72	0.013
protein targeting to lysosome	GO:0006622	5	0.013
regulation of ras gtpase activity	GO:0032318	38	0.013
regulation of cell size	GO:0008361	63	0.013
macroautophagy	GO:0016236	42	0.013
meiotic cell cycle process	GO:1903046	132	0.013
regulation of apoptotic process	GO:0042981	130	0.013
chitin based cuticle sclerotization	GO:0007593	19	0.013
stem cell differentiation	GO:0048863	117	0.013
branched chain amino acid transport	GO:0015803	3	0.013
cellular response to biotic stimulus	GO:0071216	4	0.013
negative regulation of biosynthetic process	GO:0009890	277	0.013
cellular macromolecule catabolic process	GO:0044265	136	0.013

Rab2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.024
	nervous system disease	DOID:863	0	0.014

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