Drosophila melanogaster

80 known processes

Eb1 (Dmel_CG3265)

CG3265 gene product from transcript CG3265-RF

(Aliases: anon-EST:Liang-2.33,eb1,l(2)04524,DmEB1,Dm EB1,dEB-1,BcDNA:LD08743,clone 2.52,EB-1,anon-EST:Liang-2.52,BcDNA.LD08743,S(DmcycE[JP])2.5,EB1,clone 2.33,l(2)4524,CG3265,dEb1,dEB1,Dmel\CG3265)

Eb1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
microtubule organizing center organizationGO:00310231680.941
spindle organizationGO:00070512530.908
melanotic encapsulation of foreign targetGO:0035011300.896
establishment or maintenance of cytoskeleton polarityGO:0030952440.823
secondary metabolic processGO:0019748750.769
eye morphogenesisGO:00485922600.745
eye developmentGO:00016543230.740
centrosome organizationGO:00512971630.718
mitotic spindle organizationGO:00070522200.630
regulation of microtubule cytoskeleton organizationGO:0070507410.619
Human
centrosome cycleGO:00070981370.578
pigment metabolic processGO:0042440840.544
encapsulation of foreign targetGO:0035010380.528
regulation of microtubule based processGO:0032886490.505
Human
blastoderm segmentationGO:00073501590.503
protein polymerizationGO:0051258420.493
Human
sensory organ morphogenesisGO:00905962600.466
regulation of localizationGO:00328792750.451
organic hydroxy compound metabolic processGO:1901615830.447
cellularizationGO:0007349900.429
organelle localizationGO:00516401480.384
endocytosisGO:00068973100.382
regulation of cytoskeleton organizationGO:0051493890.371
Human
cell migrationGO:00164772380.369
cellular macromolecular complex assemblyGO:00346221530.368
Human
melanization defense responseGO:0035006450.340
rna localizationGO:00064031150.335
epithelial cell migrationGO:00106311480.328
multicellular organismal agingGO:00102591400.324
melanin metabolic processGO:0006582470.321
cellular protein complex assemblyGO:0043623710.318
Human
actin cytoskeleton organizationGO:00300362060.315
microtubule polymerization or depolymerizationGO:0031109390.312
Human
establishment or maintenance of cell polarityGO:00071631670.299
nuclear divisionGO:00002803320.288
regulation of cellular localizationGO:00603411360.288
regulation of cellular component biogenesisGO:00440872010.277
Human
single organism cellular localizationGO:19025801800.252
sensory perceptionGO:00076001960.249
synaptic transmissionGO:00072682880.244
localization of cellGO:00516742570.241
cortical actin cytoskeleton organizationGO:0030866240.239
spermatid differentiationGO:00485151140.235
determination of adult lifespanGO:00083401370.231
compound eye morphogenesisGO:00017452490.217
cellular macromolecule localizationGO:00707272200.213
Human Mouse
protein complex biogenesisGO:00702712010.208
positive regulation of cellular component organizationGO:00511301560.206
centrosome duplicationGO:00512981210.204
compound eye developmentGO:00487493070.203
protein localizationGO:00081042840.202
Human Mouse
mapk cascadeGO:00001651070.199
regulation of synaptic transmissionGO:0050804690.196
regulation of nervous system developmentGO:00519602480.195
protein targeting to nucleusGO:0044744510.190
actin filament organizationGO:00070151260.186
regulation of intracellular signal transductionGO:19025312360.184
Fly
embryonic pattern specificationGO:00098801740.181
nucleus localizationGO:0051647340.178
intracellular transportGO:00469072280.178
phagocytosisGO:00069092150.175
segmentationGO:00352822070.171
spindle assembly involved in mitosisGO:0090307500.165
mitotic spindle elongationGO:0000022810.162
microtubule polymerizationGO:0046785150.161
Human
regulation of transportGO:00510491810.157
protein importGO:0017038550.152
dendrite morphogenesisGO:00488131990.148
cell motilityGO:00488702510.147
regulation of synaptic growth at neuromuscular junctionGO:0008582890.141
protein modification processGO:00362114380.140
Mouse
skeletal muscle organ developmentGO:0060538480.137
innate immune responseGO:00450871440.135
eye photoreceptor cell developmentGO:0042462810.134
immune effector processGO:0002252980.131
axon extension involved in axon guidanceGO:0048846100.131
response to light stimulusGO:00094161240.131
single organism nuclear importGO:1902593510.129
oocyte microtubule cytoskeleton organizationGO:0016325350.129
pronuclear migrationGO:003504640.129
microtubule cytoskeleton organization involved in mitosisGO:1902850520.128
oocyte differentiationGO:00099941450.126
response to radiationGO:00093141550.125
embryonic development via the syncytial blastodermGO:00017001480.124
small gtpase mediated signal transductionGO:0007264880.121
establishment of organelle localizationGO:00516561220.119
establishment or maintenance of bipolar cell polarityGO:0061245340.119
cellular protein localizationGO:00346131600.117
Human Mouse
forebrain developmentGO:003090020.116
vesicle mediated transportGO:00161923810.116
sister chromatid segregationGO:0000819920.116
female meiotic divisionGO:0007143700.113
neuron projection guidanceGO:00974852410.113
intracellular signal transductionGO:00355563000.111
Fly
cell cell junction assemblyGO:0007043380.108
immune response regulating signaling pathwayGO:000276420.108
photoreceptor cell differentiationGO:00465301700.108
single organism behaviorGO:00447083910.107
immune responseGO:00069552460.107
regulation of intracellular protein transportGO:0033157460.106
positive regulation of cytoskeleton organizationGO:0051495210.106
response to bacteriumGO:00096171980.105
lateral inhibitionGO:00463312060.105
intracellular mrna localization involved in anterior posterior axis specificationGO:0060811530.104
photoreceptor cell developmentGO:0042461960.104
maternal determination of anterior posterior axis embryoGO:0008358740.103
nucleocytoplasmic transportGO:0006913720.100
detection of stimulusGO:00516061560.096
muscle structure developmentGO:00610612240.096
actomyosin structure organizationGO:0031032560.090
apoptotic cell clearanceGO:0043277140.088
synapse assemblyGO:00074161430.088
fertilizationGO:0009566260.088
defense responseGO:00069523000.086
locomotory behaviorGO:00076261760.086
neurological system processGO:00508773580.086
nuclear importGO:0051170510.085
respiratory system developmentGO:00605412130.084
response to abiotic stimulusGO:00096283410.084
cellular protein complex disassemblyGO:0043624350.081
spindle assemblyGO:0051225800.081
neural precursor cell proliferationGO:0061351750.080
cortical cytoskeleton organizationGO:0030865290.078
heterocycle catabolic processGO:00467001660.077
phenol containing compound metabolic processGO:0018958570.077
open tracheal system developmentGO:00074242040.077
pole cell formationGO:0007279190.077
positive regulation of cell communicationGO:00106472500.076
Fly
actin filament based processGO:00300292200.076
oocyte anterior posterior axis specificationGO:0007314720.075
regulation of mapk cascadeGO:0043408920.075
positive regulation of nfat protein import into nucleusGO:0051533160.075
establishment of neuroblast polarityGO:004520020.074
positive regulation of phosphorus metabolic processGO:00105621390.073
Mouse
tissue morphogenesisGO:00487292970.072
pole cell developmentGO:0007277260.071
organelle fissionGO:00482853400.071
head developmentGO:00603221350.070
axon developmentGO:00615642970.070
muscle cell differentiationGO:00426921030.069
macromolecular complex disassemblyGO:0032984370.067
salivary gland developmentGO:00074311620.067
mitotic nuclear divisionGO:00070672130.066
epithelial cell morphogenesis involved in gastrulationGO:000338170.065
cellular component disassemblyGO:0022411460.065
regulation of cell morphogenesisGO:00226041630.064
regulation of protein localizationGO:0032880760.064
transmembrane transportGO:00550851390.062
macromolecular complex assemblyGO:00650032560.061
ribonucleoside triphosphate metabolic processGO:00091991190.061
eggshell formationGO:00307031050.061
eye photoreceptor cell differentiationGO:00017541450.060
ovarian follicle cell developmentGO:00307072480.060
cellular macromolecule catabolic processGO:00442651360.060
organelle fusionGO:0048284460.060
negative regulation of signalingGO:00230572190.059
microtubule based transportGO:0010970420.058
cell junction organizationGO:0034330570.057
ubiquitin dependent protein catabolic processGO:0006511780.057
nucleoside triphosphate catabolic processGO:00091431080.055
response to other organismGO:00517072930.055
regulation of cellular protein metabolic processGO:00322682430.054
Mouse
signal transduction by phosphorylationGO:00230141070.054
positive regulation of apoptotic cell clearanceGO:200042720.054
single organism intracellular transportGO:19025822070.053
axonogenesisGO:00074092900.053
exocrine system developmentGO:00352721620.052
developmental growthGO:00485892800.052
maintenance of cell polarityGO:0030011180.052
regulation of protein localization to nucleusGO:1900180290.052
protein localization to organelleGO:0033365820.051
Human Mouse
microtubule anchoringGO:0034453110.051
nuclear transportGO:0051169720.050
phosphorylationGO:00163102940.050
Mouse
regulation of cell shapeGO:00083601130.050
cytoplasmic transportGO:00164821300.049
chromosome organizationGO:00512763600.049
organelle assemblyGO:00709251980.049
central nervous system developmentGO:00074172010.049
maintenance of protein locationGO:0045185280.049
positive regulation of dendrite morphogenesisGO:005077590.048
regulation of anatomical structure morphogenesisGO:00226032420.048
regulation of protein complex disassemblyGO:0043244290.047
organic substance catabolic processGO:19015753080.047
vesicle localizationGO:0051648550.046
regulation of protein polymerizationGO:0032271280.046
Human
positive regulation of signal transductionGO:00099672230.046
Fly
establishment of nucleus localizationGO:0040023260.045
response to biotic stimulusGO:00096072940.044
protein localization to nucleusGO:0034504550.044
organic substance transportGO:00717022570.044
brain developmentGO:00074201200.043
response to lipopolysaccharideGO:003249640.043
regulation of synapse organizationGO:00508071100.043
detection of external stimulusGO:0009581660.043
regulation of phosphorus metabolic processGO:00511742100.043
Mouse
positive regulation of phagocytosisGO:005076630.042
ribonucleoside triphosphate catabolic processGO:00092031080.042
positive regulation of macromolecule metabolic processGO:00106044050.042
Mouse
immune response activating signal transductionGO:000275720.042
protein import into nucleusGO:0006606510.041
cellular protein catabolic processGO:0044257830.041
cell cell junction organizationGO:0045216550.041
adult locomotory behaviorGO:0008344760.041
positive regulation of transcription factor import into nucleusGO:0042993190.041
retina development in camera type eyeGO:006004140.040
posttranscriptional gene silencing by rnaGO:0035194450.040
regulation of nucleocytoplasmic transportGO:0046822350.040
establishment of localization in cellGO:00516494020.040
positive regulation of response to stimulusGO:00485843230.040
Fly
cellular component assembly involved in morphogenesisGO:00109271510.040
myosin filament assemblyGO:003103450.040
positive regulation of lipid biosynthetic processGO:004688930.039
negative regulation of cellular component organizationGO:00511291080.039
Human
establishment of protein localization to organelleGO:0072594620.039
striated muscle myosin thick filament assemblyGO:007168830.037
protein targetingGO:0006605640.037
agingGO:00075681430.037
convergent extensionGO:006002620.037
glial cell differentiationGO:0010001350.037
cell proliferationGO:00082832990.037
establishment or maintenance of neuroblast polarityGO:004519680.037
engulfment of apoptotic cellGO:004365260.037
nitrogen compound transportGO:0071705850.036
gland developmentGO:00487321910.036
establishment of cell polarityGO:0030010400.036
organic cyclic compound catabolic processGO:19013611680.035
microtubule based movementGO:0007018510.035
imaginal disc derived appendage morphogenesisGO:00351143950.035
nucleus organizationGO:0006997450.034
positive regulation of cell cycleGO:0045787430.034
Mouse
embryo development ending in birth or egg hatchingGO:00097921520.034
regulation of centrosome cycleGO:004660570.034
positive regulation of phosphate metabolic processGO:00459371390.034
Mouse
peripheral nervous system developmentGO:0007422520.034
morphogenesis of an epitheliumGO:00020092760.034
gland morphogenesisGO:00226121450.033
pseudocleavage involved in syncytial blastoderm formationGO:003058990.033
protein complex assemblyGO:00064612000.033
cellular ketone metabolic processGO:0042180240.033
camera type eye developmentGO:004301040.033
embryonic morphogenesisGO:00485982060.032
retina morphogenesis in camera type eyeGO:006004220.032
positive regulation of intracellular transportGO:0032388420.032
rhabdomere developmentGO:0042052380.032
ras protein signal transductionGO:0007265880.032
germarium derived oocyte differentiationGO:0030706290.032
regulation of phosphate metabolic processGO:00192202100.032
Mouse
meiotic spindle organizationGO:0000212360.031
synaptic growth at neuromuscular junctionGO:00511241190.030
regulation of actin filament lengthGO:0030832270.030
tripartite regional subdivisionGO:00073511030.030
dendrite developmentGO:00163582040.030
regulation of protein transportGO:0051223570.030
neuromuscular junction developmentGO:00075281490.029
regulation of intracellular transportGO:0032386640.029
regulation of synapse assemblyGO:0051963940.029
oxoacid metabolic processGO:00434361030.028
regulation of proteolysisGO:0030162870.028
neuron maturationGO:0042551310.028
nucleobase containing compound transportGO:0015931560.028
positive regulation of nucleocytoplasmic transportGO:0046824240.028
single organism membrane organizationGO:0044802930.028
gene silencingGO:00164581380.027
ion transportGO:00068111450.027
appendage developmentGO:00487364010.027
positive regulation of transportGO:0051050920.027
ribonucleoside monophosphate catabolic processGO:0009158390.026
regulation of cell cycle phase transitionGO:19019871300.026
telencephalon developmentGO:002153720.026
adult behaviorGO:00305341370.026
regulation of phagocytosis engulfmentGO:006009910.026
defense response to other organismGO:00985422250.025
regulation of protein metabolic processGO:00512462560.025
Mouse
proteasomal protein catabolic processGO:0010498590.025
establishment of spindle orientationGO:0051294180.025
meiotic cell cycle processGO:19030461320.025
positive regulation of catalytic activityGO:00430851180.025
Mouse
regulation of hemocyte proliferationGO:0035206370.025
multi organism behaviorGO:00517051750.025
intracellular mrna localization involved in pattern specification processGO:0060810560.025
axon midline choice point recognitionGO:0016199260.025
negative regulation of phosphatase activityGO:001092330.025
oocyte axis specificationGO:00073091080.024
cellular catabolic processGO:00442483720.024
regulation of synapse structure and activityGO:00508031280.024
cell junction assemblyGO:0034329420.024
regulation of dendrite morphogenesisGO:0048814280.023
mitotic sister chromatid segregationGO:0000070870.023
proteolysisGO:00065081920.023
olfactory bulb axon guidanceGO:007167830.023
entry into cell of other organism involved in symbiotic interactionGO:005180630.023
purine nucleotide catabolic processGO:00061951090.023
organonitrogen compound catabolic processGO:19015651280.023
purine nucleoside monophosphate metabolic processGO:0009126500.023
single fertilizationGO:0007338240.022
negative regulation of cellular protein metabolic processGO:0032269850.022
positive regulation of cellular component biogenesisGO:0044089800.022
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.022
immune system processGO:00023763470.022
regulation of cytoplasmic transportGO:1903649470.022
epithelial cell differentiationGO:00308553220.022
regulation of protein import into nucleusGO:0042306280.022
nucleobase containing small molecule metabolic processGO:00550861740.022
regulation of protein phosphatase type 2a activityGO:003404720.021
mushroom body developmentGO:0016319700.021
regulation of locomotionGO:0040012420.021
regulation of transcription factor import into nucleusGO:0042990220.021
regulation of axonogenesisGO:0050770320.021
steroid catabolic processGO:000670610.021
cell projection assemblyGO:0030031940.021
multicellular organismal reproductive behaviorGO:00330571100.021
dna catabolic processGO:0006308160.021
protein adp ribosylationGO:000647140.020
asymmetric neuroblast divisionGO:0055059330.020
nuclear migrationGO:0007097200.020
protein catabolic processGO:00301631010.020
morphogenesis of embryonic epitheliumGO:0016331940.020
anterior posterior axis specification embryoGO:00085951030.020
appendage morphogenesisGO:00351073970.020
maintenance of location in cellGO:0051651280.020
protein transportGO:00150311550.020
membrane disassemblyGO:003039740.020
small molecule metabolic processGO:00442813050.020
positive regulation of phosphorylationGO:0042327870.019
Mouse
salivary gland morphogenesisGO:00074351450.019
axon guidanceGO:00074112330.019
positive regulation of immune system processGO:0002684680.019
maintenance of locationGO:0051235730.019
regulation of molecular functionGO:00650092170.019
Mouse
nucleoside phosphate metabolic processGO:00067531620.019
cytokinesisGO:0000910900.019
regulation of cellular amine metabolic processGO:003323830.019
carbohydrate derivative metabolic processGO:19011352170.018
regulation of filopodium assemblyGO:0051489240.018
positive regulation of intracellular signal transductionGO:19025331160.018
Fly
meiotic nuclear divisionGO:00071261510.018
male meiosis cytokinesisGO:0007112260.018
heparin metabolic processGO:003020240.018
compound eye photoreceptor developmentGO:0042051780.018
myosin filament organizationGO:003103350.018
positive regulation of protein import into nucleusGO:0042307210.018
salivary gland cell autophagic cell deathGO:0035071830.018
purine containing compound catabolic processGO:00725231120.018
neural retina developmentGO:000340740.018
regulation of multi organism processGO:00439001310.018
establishment of spindle localizationGO:0051293220.017
gastrulationGO:0007369700.017
regulation of protein phosphorylationGO:0001932640.017
Mouse
regulation of metaphase anaphase transition of cell cycleGO:1902099260.017
learning or memoryGO:00076111410.017
response to external biotic stimulusGO:00432072930.017
regulation of phosphorylationGO:00423251470.017
Mouse
positive regulation of protein polymerizationGO:0032273140.017
response to extracellular stimulusGO:00099911160.017
spermatid nucleus elongationGO:000729040.017
positive regulation of nervous system developmentGO:0051962690.016
histolysisGO:00075591020.016
purine ribonucleoside triphosphate catabolic processGO:00092071080.016
neuroblast proliferationGO:0007405740.016
regulation of embryonic cell shapeGO:0016476300.016
phototransductionGO:0007602520.016
hemocyte migrationGO:0035099190.015
negative regulation of cytoskeleton organizationGO:0051494300.015
Human
purine nucleoside triphosphate metabolic processGO:00091441190.015
posttranscriptional regulation of gene expressionGO:00106081450.015
regulation of mitosisGO:0007088560.015
epithelial cell developmentGO:00020642740.015
movement in environment of other organism involved in symbiotic interactionGO:005219230.015
catabolic processGO:00090564090.015
regulation of nfat protein import into nucleusGO:0051532160.015
positive regulation of phagocytosis engulfmentGO:006010010.015
maintenance of protein location in cellGO:0032507260.015
g protein coupled receptor signaling pathwayGO:00071861360.014
asymmetric cell divisionGO:0008356370.014
proteolysis involved in cellular protein catabolic processGO:0051603830.014
regulation of establishment of protein localizationGO:0070201610.014
phagocytosis engulfmentGO:0006911110.014
positive regulation of proteasomal protein catabolic processGO:1901800200.014
ribose phosphate metabolic processGO:00196931450.014
nucleoside catabolic processGO:00091641120.014
positive regulation of protein localization to nucleusGO:1900182210.014
epithelial tube morphogenesisGO:0060562880.014
regulation of cellular ketone metabolic processGO:001056530.014
lipid biosynthetic processGO:0008610460.014
single organism catabolic processGO:00447122280.014
actin filament based movementGO:0030048260.014
regulation of ion transmembrane transporter activityGO:003241260.014
establishment or maintenance of microtubule cytoskeleton polarityGO:0030951410.013
regulation of cell adhesionGO:0030155270.013
muscle system processGO:0003012210.013
regulation of cellular protein catabolic processGO:1903362440.013
positive regulation of establishment of protein localization to plasma membraneGO:009000430.013
establishment of protein localizationGO:00451841630.013
atp catabolic processGO:0006200380.013
regulation of axon regenerationGO:004867940.013
myofibril assemblyGO:0030239360.013
regulation of endocytosisGO:0030100370.013
regulation of cell differentiationGO:00455953020.013
response to carbon dioxideGO:001003740.013
nucleoside phosphate catabolic processGO:19012921100.013
ovarian follicle cell migrationGO:00072971210.013
centrosome separationGO:0051299200.013
regulation of striated muscle contractionGO:000694220.013
embryonic axis specificationGO:00005781070.012
regulation of cell developmentGO:00602842150.012
protein complex disassemblyGO:0043241360.012
salivary gland histolysisGO:0035070880.012
imaginal disc derived appendage developmentGO:00487373990.012
organophosphate catabolic processGO:00464341120.012
regulation of neuron differentiationGO:00456641030.012
sensory perception of chemical stimulusGO:00076061160.012
establishment of monopolar cell polarityGO:0061162150.012
negative regulation of molecular functionGO:0044092510.012
peripheral nervous system neuron developmentGO:004893580.012
cellular response to carbohydrate stimulusGO:007132240.012
organic acid metabolic processGO:00060821030.012
pole plasm mrna localizationGO:0019094490.012
sensory perception of touchGO:0050975110.012
glycosyl compound metabolic processGO:19016571270.012
biological adhesionGO:00226101380.012
digestive system developmentGO:00551231490.012
positive regulation of cell morphogenesis involved in differentiationGO:0010770120.012
intracellular protein transportGO:00068861040.012
unidimensional cell growthGO:0009826150.012
epithelial cell morphogenesisGO:0003382250.012
neuron remodelingGO:0016322290.012
regulation of mitotic sister chromatid segregationGO:0033047280.012
regulation of protein depolymerizationGO:1901879270.012
negative regulation of response to stimulusGO:00485852580.011
endomembrane system organizationGO:00102561190.011
protein localization to membraneGO:0072657190.011
morphogenesis of a branching structureGO:0001763450.011
positive regulation of organelle organizationGO:0010638650.011
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.011
cellular nitrogen compound catabolic processGO:00442701650.011
regulation of protein export from nucleusGO:004682530.011
nfat protein import into nucleusGO:0051531160.011
compound eye photoreceptor cell differentiationGO:00017511400.011
regulation of hydrolase activityGO:0051336970.011
tube developmentGO:00352952440.011
germarium derived oocyte fate determinationGO:0007294260.011
intracellular mrna localizationGO:0008298660.011
regulation of mitotic metaphase anaphase transitionGO:0030071260.011
cellular response to molecule of bacterial originGO:007121930.011
positive regulation of endocytosisGO:0045807220.011
regulation of transmembrane transporter activityGO:002289860.011
positive regulation of cell projection organizationGO:0031346290.011
regulation of actin filament based processGO:0032970420.011
semaphorin plexin signaling pathwayGO:007152640.011
anterior posterior pattern specificationGO:00099521360.011
regulation of actin filament polymerizationGO:0030833250.011
aromatic compound catabolic processGO:00194391660.011
positive regulation of mapk cascadeGO:0043410630.011
nucleoside monophosphate catabolic processGO:0009125390.011
camera type eye morphogenesisGO:004859320.010
autophagic cell deathGO:0048102830.010
ribonucleotide catabolic processGO:00092611090.010
stem cell differentiationGO:00488631170.010
nonmotile primary cilium assemblyGO:003505880.010
regulation of phosphatase activityGO:001092130.010
pronuclear fusionGO:000734440.010
establishment of rna localizationGO:0051236470.010
positive regulation of synaptic growth at neuromuscular junctionGO:0045887260.010
positive regulation of protein transportGO:0051222370.010
meiotic cell cycleGO:00513211710.010
positive regulation of protein localization to plasma membraneGO:190307830.010

Eb1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
motor neuron diseaseDOID:23100.061
disease of anatomical entityDOID:700.061
amyotrophic lateral sclerosisDOID:33200.061
neurodegenerative diseaseDOID:128900.061
central nervous system diseaseDOID:33100.061
nervous system diseaseDOID:86300.061
disease of metabolismDOID:001466700.013