IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

CG12194 (Dmel_CG12194)

CG12194 gene product from transcript CG12194-RA

(Aliases: anon-EST:Posey105,Dmel\CG12194)

FLYBASE: FBgn0031636
Entrez: 33685
UniProtKB: Q9VR34
UniProtKB: E1JHT4

Process Predictions
Disease Predictions

CG12194 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
neurological system process	GO:0050877	358	0.096
establishment of localization in cell	GO:0051649	402	0.073
organonitrogen compound metabolic process	GO:1901564	318	0.066
single organism behavior	GO:0044708	391	0.050
single organism biosynthetic process	GO:0044711	206	0.049
synaptic transmission	GO:0007268	288	0.047
carbohydrate derivative metabolic process	GO:1901135	217	0.047
g protein coupled receptor signaling pathway	GO:0007186	136	0.046
response to organic substance	GO:0010033	284	0.042
death	GO:0016265	284	0.042
regulation of localization	GO:0032879	275	0.037
regulation of cell death	GO:0010941	173	0.037
cognition	GO:0050890	141	0.037
catabolic process	GO:0009056	409	0.036
appendage development	GO:0048736	401	0.036
negative regulation of response to stimulus	GO:0048585	258	0.035
intracellular transport	GO:0046907	228	0.035
cation homeostasis	GO:0055080	51	0.035
appendage morphogenesis	GO:0035107	397	0.035
ion transport	GO:0006811	145	0.035
single organism intracellular transport	GO:1902582	207	0.033
cell death	GO:0008219	279	0.033
response to abiotic stimulus	GO:0009628	341	0.032
imaginal disc derived appendage development	GO:0048737	399	0.032
locomotory behavior	GO:0007626	176	0.032
organic substance transport	GO:0071702	257	0.032
eye pigmentation	GO:0048069	43	0.031
imaginal disc derived wing morphogenesis	GO:0007476	337	0.031
homeostatic process	GO:0042592	199	0.030
phosphorylation	GO:0016310	294	0.030
small molecule metabolic process	GO:0044281	305	0.029
detection of stimulus	GO:0051606	156	0.029
single organism catabolic process	GO:0044712	228	0.028
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.028
positive regulation of response to stimulus	GO:0048584	323	0.028
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.028
response to organophosphorus	GO:0046683	2	0.028
rhythmic process	GO:0048511	106	0.028
body morphogenesis	GO:0010171	2	0.028
carboxylic acid metabolic process	GO:0019752	92	0.028
negative regulation of signaling	GO:0023057	219	0.027
positive regulation of cellular biosynthetic process	GO:0031328	316	0.027
wing disc morphogenesis	GO:0007472	344	0.027
intracellular signal transduction	GO:0035556	300	0.027
nucleobase containing small molecule metabolic process	GO:0055086	174	0.026
multicellular organismal aging	GO:0010259	140	0.026
nucleoside phosphate metabolic process	GO:0006753	162	0.026
organic acid metabolic process	GO:0006082	103	0.026
oxoacid metabolic process	GO:0043436	103	0.026
negative regulation of cell communication	GO:0010648	223	0.026
purine containing compound metabolic process	GO:0072521	155	0.025
neuron recognition	GO:0008038	101	0.025
cellular homeostasis	GO:0019725	80	0.025
response to nutrient levels	GO:0031667	114	0.025
establishment of organelle localization	GO:0051656	122	0.025
response to radiation	GO:0009314	155	0.025
regulation of transport	GO:0051049	181	0.024
positive regulation of biosynthetic process	GO:0009891	316	0.024
positive regulation of signaling	GO:0023056	243	0.024
regulation of phosphorus metabolic process	GO:0051174	210	0.024
mating	GO:0007618	120	0.023
pigment metabolic process	GO:0042440	84	0.023
carbohydrate derivative biosynthetic process	GO:1901137	85	0.023
nitrogen compound transport	GO:0071705	85	0.023
epithelial cell differentiation	GO:0030855	322	0.023
vitamin metabolic process	GO:0006766	2	0.023
organic hydroxy compound metabolic process	GO:1901615	83	0.022
proteolysis	GO:0006508	192	0.022
programmed cell death	GO:0012501	257	0.022
regulation of programmed cell death	GO:0043067	152	0.022
lipid metabolic process	GO:0006629	121	0.022
response to extracellular stimulus	GO:0009991	116	0.022
organic substance catabolic process	GO:1901575	308	0.022
protein modification process	GO:0036211	438	0.022
vesicle mediated transport	GO:0016192	381	0.021
regulation of molecular function	GO:0065009	217	0.021
purine ribonucleotide metabolic process	GO:0009150	145	0.021
axon development	GO:0061564	297	0.021
developmental pigmentation	GO:0048066	68	0.021
cellular lipid metabolic process	GO:0044255	83	0.021
response to temperature stimulus	GO:0009266	106	0.021
organelle localization	GO:0051640	148	0.021
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.021
positive regulation of cell communication	GO:0010647	250	0.021
neuron projection guidance	GO:0097485	241	0.020
chemosensory behavior	GO:0007635	106	0.020
camera type eye development	GO:0043010	4	0.020
negative regulation of signal transduction	GO:0009968	206	0.020
phagocytosis	GO:0006909	215	0.020
chemotaxis	GO:0006935	249	0.020
signal transduction by phosphorylation	GO:0023014	107	0.019
regulation of catalytic activity	GO:0050790	185	0.019
regulation of phosphate metabolic process	GO:0019220	210	0.019
negative regulation of multicellular organismal process	GO:0051241	142	0.019
mapk cascade	GO:0000165	107	0.019
eye development	GO:0001654	323	0.019
nucleotide metabolic process	GO:0009117	161	0.019
defense response to other organism	GO:0098542	225	0.019
mating behavior	GO:0007617	106	0.019
regulation of system process	GO:0044057	36	0.018
localization of cell	GO:0051674	257	0.018
ribonucleotide metabolic process	GO:0009259	145	0.018
cyclic nucleotide metabolic process	GO:0009187	28	0.018
amine metabolic process	GO:0009308	12	0.018
organic cyclic compound catabolic process	GO:1901361	168	0.018
forebrain development	GO:0030900	2	0.018
positive regulation of phosphate metabolic process	GO:0045937	139	0.018
protein complex biogenesis	GO:0070271	201	0.018
post embryonic appendage morphogenesis	GO:0035120	385	0.018
adult behavior	GO:0030534	137	0.018
organophosphate metabolic process	GO:0019637	195	0.018
positive regulation of signal transduction	GO:0009967	223	0.018
response to biotic stimulus	GO:0009607	294	0.018
central nervous system development	GO:0007417	201	0.017
axonogenesis	GO:0007409	290	0.017
detection of light stimulus	GO:0009583	58	0.017
organonitrogen compound biosynthetic process	GO:1901566	117	0.017
compound eye development	GO:0048749	307	0.017
tissue migration	GO:0090130	155	0.017
cellular ketone metabolic process	GO:0042180	24	0.017
purine nucleotide metabolic process	GO:0006163	146	0.017
regulation of cellular localization	GO:0060341	136	0.017
endocytosis	GO:0006897	310	0.017
regulation of protein metabolic process	GO:0051246	256	0.017
heterocycle catabolic process	GO:0046700	166	0.017
tube development	GO:0035295	244	0.017
cytoplasmic transport	GO:0016482	130	0.017
cellular protein modification process	GO:0006464	438	0.017
ribose phosphate metabolic process	GO:0019693	145	0.017
learning	GO:0007612	75	0.017
negative regulation of cellular metabolic process	GO:0031324	382	0.017
cellular amide metabolic process	GO:0043603	80	0.017
regulation of multi organism process	GO:0043900	131	0.017
regulation of developmental growth	GO:0048638	174	0.017
regulation of apoptotic process	GO:0042981	130	0.016
cell proliferation	GO:0008283	299	0.016
organelle fission	GO:0048285	340	0.016
regulation of immune system process	GO:0002682	176	0.016
protein localization	GO:0008104	284	0.016
polyol biosynthetic process	GO:0046173	3	0.016
regulation of cellular ketone metabolic process	GO:0010565	3	0.016
ras protein signal transduction	GO:0007265	88	0.016
response to oxygen containing compound	GO:1901700	200	0.016
aging	GO:0007568	143	0.016
chaeta development	GO:0022416	97	0.016
regulation of cell development	GO:0060284	215	0.016
pigmentation	GO:0043473	75	0.016
axon guidance	GO:0007411	233	0.016
cellular nitrogen compound catabolic process	GO:0044270	165	0.015
chemical homeostasis	GO:0048878	92	0.015
metal ion homeostasis	GO:0055065	44	0.015
positive regulation of catalytic activity	GO:0043085	118	0.015
cell recognition	GO:0008037	102	0.015
glycosyl compound catabolic process	GO:1901658	112	0.015
single organism membrane organization	GO:0044802	93	0.015
cellular response to chemical stimulus	GO:0070887	199	0.015
adult locomotory behavior	GO:0008344	76	0.015
morphogenesis of an epithelium	GO:0002009	276	0.015
neuropeptide signaling pathway	GO:0007218	45	0.015
cell motility	GO:0048870	251	0.015
response to other organism	GO:0051707	293	0.015
camera type eye morphogenesis	GO:0048593	2	0.015
regulation of intracellular signal transduction	GO:1902531	236	0.015
acetylcholine metabolic process	GO:0008291	2	0.015
l amino acid import	GO:0043092	2	0.015
membrane organization	GO:0061024	112	0.015
protein transport	GO:0015031	155	0.015
regulation of anatomical structure size	GO:0090066	163	0.015
secondary metabolic process	GO:0019748	75	0.015
exocrine system development	GO:0035272	162	0.015
digestive tract development	GO:0048565	149	0.015
determination of adult lifespan	GO:0008340	137	0.015
regulation of cell cycle	GO:0051726	291	0.015
cellular amine metabolic process	GO:0044106	12	0.014
developmental programmed cell death	GO:0010623	138	0.014
rna localization	GO:0006403	115	0.014
regulation of phosphorylation	GO:0042325	147	0.014
single organism cellular localization	GO:1902580	180	0.014
regulation of cell differentiation	GO:0045595	302	0.014
positive regulation of macromolecule metabolic process	GO:0010604	405	0.014
taxis	GO:0042330	304	0.014
regulation of cellular protein metabolic process	GO:0032268	243	0.014
cation transport	GO:0006812	110	0.014
cellular amino acid metabolic process	GO:0006520	61	0.014
nuclear division	GO:0000280	332	0.014
cell migration	GO:0016477	238	0.014
intracellular protein transport	GO:0006886	104	0.014
phototransduction	GO:0007602	52	0.014
kidney development	GO:0001822	3	0.014
translation	GO:0006412	69	0.014
olfactory behavior	GO:0042048	97	0.014
salivary gland cell autophagic cell death	GO:0035071	83	0.014
kidney epithelium development	GO:0072073	3	0.014
response to external biotic stimulus	GO:0043207	293	0.014
regulation of synapse structure and activity	GO:0050803	128	0.014
positive regulation of molecular function	GO:0044093	136	0.014
defense response to bacterium	GO:0042742	178	0.014
apoptotic process	GO:0006915	159	0.014
endomembrane system organization	GO:0010256	119	0.014
positive regulation of purine nucleotide metabolic process	GO:1900544	55	0.014
circadian rhythm	GO:0007623	105	0.014
negative regulation of developmental process	GO:0051093	201	0.014
small gtpase mediated signal transduction	GO:0007264	88	0.013
response to lipopolysaccharide	GO:0032496	4	0.013
gland morphogenesis	GO:0022612	145	0.013
regulation of cellular amine metabolic process	GO:0033238	3	0.013
protein complex assembly	GO:0006461	200	0.013
autophagic cell death	GO:0048102	83	0.013
organonitrogen compound catabolic process	GO:1901565	128	0.013
stress activated protein kinase signaling cascade	GO:0031098	55	0.013
cellular protein localization	GO:0034613	160	0.013
tissue morphogenesis	GO:0048729	297	0.013
regionalization	GO:0003002	416	0.013
synaptic target recognition	GO:0008039	45	0.013
regulation of multicellular organismal development	GO:2000026	414	0.013
positive regulation of nucleotide metabolic process	GO:0045981	55	0.013
sensory organ morphogenesis	GO:0090596	260	0.013
learning or memory	GO:0007611	141	0.013
memory	GO:0007613	94	0.013
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger	GO:0007187	17	0.013
positive regulation of cell motility	GO:2000147	3	0.013
ion homeostasis	GO:0050801	55	0.013
connective tissue development	GO:0061448	3	0.013
regulation of nervous system development	GO:0051960	248	0.013
aromatic compound catabolic process	GO:0019439	166	0.013
telencephalon development	GO:0021537	2	0.013
transmembrane transport	GO:0055085	139	0.013
circadian behavior	GO:0048512	76	0.013
regulation of cellular component biogenesis	GO:0044087	201	0.013
retina development in camera type eye	GO:0060041	4	0.012
response to alcohol	GO:0097305	95	0.012
cellular macromolecule localization	GO:0070727	220	0.012
positive regulation of gene expression	GO:0010628	290	0.012
cellular ion homeostasis	GO:0006873	39	0.012
detection of abiotic stimulus	GO:0009582	66	0.012
tissue death	GO:0016271	102	0.012
embryonic development via the syncytial blastoderm	GO:0001700	148	0.012
ethanolamine containing compound metabolic process	GO:0042439	4	0.012
macromolecular complex assembly	GO:0065003	256	0.012
compound eye morphogenesis	GO:0001745	249	0.012
positive regulation of phosphorus metabolic process	GO:0010562	139	0.012
synaptic vesicle transport	GO:0048489	50	0.012
response to hexose	GO:0009746	3	0.012
sensory perception of chemical stimulus	GO:0007606	116	0.012
developmental growth	GO:0048589	280	0.012
positive regulation of cell migration	GO:0030335	2	0.012
circulatory system process	GO:0003013	37	0.012
epidermal growth factor receptor signaling pathway	GO:0007173	58	0.012
medium chain fatty acid metabolic process	GO:0051791	1	0.012
defense response	GO:0006952	300	0.012
synapse organization	GO:0050808	196	0.012
retina morphogenesis in camera type eye	GO:0060042	2	0.012
epithelial cell development	GO:0002064	274	0.012
ameboidal type cell migration	GO:0001667	151	0.012
regulation of circadian rhythm	GO:0042752	49	0.012
eye pigment metabolic process	GO:0042441	33	0.011
pigment metabolic process involved in pigmentation	GO:0043474	33	0.011
chromosome segregation	GO:0007059	157	0.011
regulation of heart rate	GO:0002027	11	0.011
toxin metabolic process	GO:0009404	2	0.011
neuromuscular junction development	GO:0007528	149	0.011
positive regulation of intracellular signal transduction	GO:1902533	116	0.011
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.011
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.011
ribonucleoside metabolic process	GO:0009119	127	0.011
purine ribonucleoside metabolic process	GO:0046128	127	0.011
anatomical structure homeostasis	GO:0060249	97	0.011
motor neuron axon guidance	GO:0008045	58	0.011
response to monosaccharide	GO:0034284	4	0.011
salivary gland morphogenesis	GO:0007435	145	0.011
histolysis	GO:0007559	102	0.011
developmental maturation	GO:0021700	172	0.011
response to endogenous stimulus	GO:0009719	119	0.011
microtubule based movement	GO:0007018	51	0.011
nephron development	GO:0072006	3	0.011
salivary gland histolysis	GO:0035070	88	0.011
organophosphate biosynthetic process	GO:0090407	46	0.011
positive regulation of transport	GO:0051050	92	0.011
response to bacterium	GO:0009617	198	0.011
associative learning	GO:0008306	65	0.011
eye morphogenesis	GO:0048592	260	0.011
cellular macromolecular complex assembly	GO:0034622	153	0.011
ribonucleoside catabolic process	GO:0042454	112	0.011
olfactory learning	GO:0008355	56	0.011
membrane fusion	GO:0061025	42	0.011
regulation of i kappab kinase nf kappab signaling	GO:0043122	2	0.011
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.011
secretion	GO:0046903	109	0.011
macromolecule catabolic process	GO:0009057	161	0.011
monocarboxylic acid transport	GO:0015718	3	0.011
negative regulation of growth	GO:0045926	84	0.011
organelle fusion	GO:0048284	46	0.011
cellular cation homeostasis	GO:0030003	38	0.011
negative regulation of cellular component organization	GO:0051129	108	0.010
lateral inhibition	GO:0046331	206	0.010
neurotransmitter metabolic process	GO:0042133	2	0.010
sleep	GO:0030431	49	0.010
detection of chemical stimulus	GO:0009593	93	0.010
neuromuscular synaptic transmission	GO:0007274	67	0.010
response to nitrogen compound	GO:1901698	90	0.010
regulation of cellular amino acid metabolic process	GO:0006521	0	0.010
lipid biosynthetic process	GO:0008610	46	0.010
carbohydrate derivative catabolic process	GO:1901136	118	0.010
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.010
cellular macromolecule catabolic process	GO:0044265	136	0.010
regulation of mapk cascade	GO:0043408	92	0.010
cellular response to carbohydrate stimulus	GO:0071322	4	0.010
establishment of protein localization	GO:0045184	163	0.010
regulation of cell proliferation	GO:0042127	163	0.010
nucleoside catabolic process	GO:0009164	112	0.010
stress activated mapk cascade	GO:0051403	52	0.010
regulation of ras protein signal transduction	GO:0046578	93	0.010
response to oxidative stress	GO:0006979	86	0.010
actin cytoskeleton organization	GO:0030036	206	0.010

CG12194 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.046
nervous system disease	DOID:863	0.030
disease of metabolism	DOID:0014667	0.020
cardiovascular system disease	DOID:1287	0.018
musculoskeletal system disease	DOID:17	0.016
inherited metabolic disorder	DOID:655	0.014
sensory system disease	DOID:0050155	0.013
eye and adnexa disease	DOID:1492	0.013
central nervous system disease	DOID:331	0.012
artery disease	DOID:0050828	0.012
vascular disease	DOID:178	0.012
hypertension	DOID:10763	0.012
essential hypertension	DOID:10825	0.012
eye disease	DOID:5614	0.011
type 2 diabetes mellitus	DOID:9352	0.011
carbohydrate metabolism disease	DOID:0050013	0.011
acquired metabolic disease	DOID:0060158	0.011
diabetes mellitus	DOID:9351	0.011
glucose metabolism disease	DOID:4194	0.011
disease of cellular proliferation	DOID:14566	0.011
cancer	DOID:162	0.011
neurodegenerative disease	DOID:1289	0.010

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