Drosophila melanogaster

69 known processes

iHog (Dmel_CG9211)

interference Hedgehog

(Aliases: CT26314,Dmel\CG9211,Ihog,ihog,CG9211)

iHog biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
tissue morphogenesisGO:00487292970.937
Mouse
morphogenesis of an epitheliumGO:00020092760.496
eye morphogenesisGO:00485922600.467
cellular protein modification processGO:00064644380.451
Mouse
regionalizationGO:00030024160.354
negative regulation of cellular biosynthetic processGO:00313272770.219
negative regulation of rna biosynthetic processGO:19026792400.194
regulation of molecular functionGO:00650092170.185
Mouse
camera type eye developmentGO:004301040.182
Mouse
protein modification processGO:00362114380.174
Mouse
respiratory system developmentGO:00605412130.173
negative regulation of cell communicationGO:00106482230.160
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.151
negative regulation of biosynthetic processGO:00098902770.148
negative regulation of cellular metabolic processGO:00313243820.146
regulation of cellular catabolic processGO:00313291570.146
eye developmentGO:00016543230.133
negative regulation of transcription dna templatedGO:00458922370.127
negative regulation of response to stimulusGO:00485852580.126
cell motilityGO:00488702510.118
negative regulation of rna metabolic processGO:00512532510.113
neurological system processGO:00508773580.112
epithelial tube morphogenesisGO:0060562880.111
sensory organ morphogenesisGO:00905962600.111
cell migrationGO:00164772380.111
regulation of anatomical structure morphogenesisGO:00226032420.106
negative regulation of nucleic acid templated transcriptionGO:19035072400.096
positive regulation of molecular functionGO:00440931360.096
negative regulation of gene expressionGO:00106293870.095
negative regulation of nucleobase containing compound metabolic processGO:00459342610.093
cellular amine metabolic processGO:0044106120.093
covalent chromatin modificationGO:00165691060.092
positive regulation of cell communicationGO:00106472500.091
response to organic substanceGO:00100332840.089
regulation of cellular ketone metabolic processGO:001056530.085
regulation of cell morphogenesisGO:00226041630.085
cellular protein localizationGO:00346131600.081
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.073
appendage developmentGO:00487364010.072
phosphorylationGO:00163102940.071
Mouse
anterior posterior pattern specificationGO:00099521360.070
Mouse
positive regulation of cellular protein metabolic processGO:00322701180.069
Mouse
positive regulation of nucleobase containing compound metabolic processGO:00459353320.069
Mouse
organonitrogen compound metabolic processGO:19015643180.068
regulation of notch signaling pathwayGO:00085931000.068
protein localizationGO:00081042840.068
positive regulation of signalingGO:00230562430.066
organophosphate metabolic processGO:00196371950.065
eye photoreceptor cell differentiationGO:00017541450.065
chromatin modificationGO:00165681470.064
regulation of cell developmentGO:00602842150.063
Mouse
mesenchymal cell differentiationGO:004876210.063
regulation of cellular component biogenesisGO:00440872010.063
developmental growthGO:00485892800.063
negative regulation of macromolecule biosynthetic processGO:00105582700.063
deathGO:00162652840.062
positive regulation of macromolecule metabolic processGO:00106044050.062
Mouse
histone modificationGO:00165701060.061
regulation of immune responseGO:00507761180.061
transcription from rna polymerase ii promoterGO:00063663680.060
Mouse
positive regulation of cysteine type endopeptidase activityGO:2001056240.060
compound eye morphogenesisGO:00017452490.059
body morphogenesisGO:001017120.058
Mouse
organic substance catabolic processGO:19015753080.057
proteolysisGO:00065081920.056
macromolecular complex assemblyGO:00650032560.056
intracellular transportGO:00469072280.055
regulation of cell deathGO:00109411730.055
negative regulation of nitrogen compound metabolic processGO:00511722650.053
embryonic morphogenesisGO:00485982060.052
Mouse
catabolic processGO:00090564090.051
response to abiotic stimulusGO:00096283410.051
cellular amino acid metabolic processGO:0006520610.050
positive regulation of protein modification processGO:0031401580.050
Mouse
regulation of gene expression epigeneticGO:00400291280.049
regulation of localizationGO:00328792750.049
positive regulation of nitrogen compound metabolic processGO:00511733540.049
Mouse
retina morphogenesis in camera type eyeGO:006004220.049
Mouse
actin filament organizationGO:00070151260.049
carbohydrate derivative metabolic processGO:19011352170.049
regulation of cellular protein metabolic processGO:00322682430.049
Mouse
localization of cellGO:00516742570.049
compound eye developmentGO:00487493070.048
regulation of cell morphogenesis involved in differentiationGO:0010769610.048
protein acetylationGO:0006473390.047
cell fate specificationGO:0001708710.046
Mouse
central nervous system developmentGO:00074172010.046
Mouse
small molecule metabolic processGO:00442813050.046
regulation of nervous system developmentGO:00519602480.045
Mouse
negative regulation of notch signaling pathwayGO:0045746410.045
epithelial cell differentiationGO:00308553220.044
chromatin organizationGO:00063252070.044
macromolecule catabolic processGO:00090571610.044
negative regulation of signal transductionGO:00099682060.044
wing disc morphogenesisGO:00074723440.043
regulation of protein metabolic processGO:00512462560.042
Mouse
regulation of programmed cell deathGO:00430671520.042
camera type eye morphogenesisGO:004859320.042
Mouse
cellular response to chemical stimulusGO:00708871990.041
post embryonic appendage morphogenesisGO:00351203850.041
positive regulation of protein metabolic processGO:00512471280.041
Mouse
embryonic organ developmentGO:0048568500.040
ribonucleoside metabolic processGO:00091191270.040
renal system developmentGO:0072001720.040
amine metabolic processGO:0009308120.039
open tracheal system developmentGO:00074242040.039
kidney developmentGO:000182230.039
negative regulation of signalingGO:00230572190.039
establishment or maintenance of cell polarityGO:00071631670.038
positive regulation of phosphate metabolic processGO:00459371390.038
Mouse
regulation of cellular amine metabolic processGO:003323830.038
positive regulation of biosynthetic processGO:00098913160.038
Mouse
multicellular organismal agingGO:00102591400.038
positive regulation of intracellular signal transductionGO:19025331160.037
Mouse
tube developmentGO:00352952440.037
cellular catabolic processGO:00442483720.037
regulation of cell proliferationGO:00421271630.036
Mouse
positive regulation of multicellular organismal processGO:00512401430.036
Mouse
single organism catabolic processGO:00447122280.036
cellular ketone metabolic processGO:0042180240.036
carboxylic acid metabolic processGO:0019752920.036
response to oxygen containing compoundGO:19017002000.036
immune responseGO:00069552460.035
positive regulation of cellular biosynthetic processGO:00313283160.035
Mouse
regulation of phosphate metabolic processGO:00192202100.033
Mouse
tube morphogenesisGO:00352391910.033
organophosphate biosynthetic processGO:0090407460.033
regulation of cell differentiationGO:00455953020.033
Mouse
chromosome organizationGO:00512763600.033
hindbrain developmentGO:003090220.032
regulation of catabolic processGO:00098941700.032
compound eye photoreceptor cell differentiationGO:00017511400.032
regulation of proteolysisGO:0030162870.032
regulation of cellular amino acid metabolic processGO:000652100.032
regulation of transcription from rna polymerase ii promoterGO:00063573780.031
Mouse
morphogenesis of a branching epitheliumGO:0061138450.031
photoreceptor cell differentiationGO:00465301700.031
head developmentGO:00603221350.031
Mouse
positive regulation of catalytic activityGO:00430851180.031
segmentationGO:00352822070.030
internal protein amino acid acetylationGO:0006475380.030
brain developmentGO:00074201200.030
Mouse
wound healingGO:0042060750.030
peptidyl amino acid modificationGO:00181931050.030
regulation of multicellular organismal developmentGO:20000264140.030
Mouse
ameboidal type cell migrationGO:00016671510.030
response to lipopolysaccharideGO:003249640.030
response to other organismGO:00517072930.029
chromatin assembly or disassemblyGO:0006333520.029
cell cell adhesion via plasma membrane adhesion moleculesGO:0098742260.029
protein processingGO:0016485680.029
histone acetylationGO:0016573380.029
cellular macromolecule localizationGO:00707272200.028
posttranscriptional regulation of gene expressionGO:00106081450.028
regulation of catalytic activityGO:00507901850.028
cell cell junction organizationGO:0045216550.028
retina development in camera type eyeGO:006004140.028
Mouse
imaginal disc pattern formationGO:0007447910.027
response to woundingGO:0009611940.027
tissue migrationGO:00901301550.027
regulation of transportGO:00510491810.026
programmed cell deathGO:00125012570.026
proteolysis involved in cellular protein catabolic processGO:0051603830.026
heart developmentGO:0007507820.026
negative regulation of gene expression epigeneticGO:0045814770.026
protein maturationGO:0051604710.026
cell deathGO:00082192790.026
protein phosphorylationGO:00064681690.026
Mouse
columnar cuboidal epithelial cell differentiationGO:00020652560.026
branching morphogenesis of an epithelial tubeGO:0048754450.025
zymogen activationGO:0031638200.025
regulation of mitotic cell cycle phase transitionGO:19019901300.025
positive regulation of endopeptidase activityGO:0010950260.025
positive regulation of response to stimulusGO:00485843230.025
establishment of localization in cellGO:00516494020.025
actin cytoskeleton organizationGO:00300362060.024
positive regulation of signal transductionGO:00099672230.024
nucleoside phosphate metabolic processGO:00067531620.024
negative regulation of developmental processGO:00510932010.024
photoreceptor cell developmentGO:0042461960.024
positive regulation of peptidase activityGO:0010952290.024
regulation of response to stressGO:00801342000.024
regulation of phosphorylationGO:00423251470.023
Mouse
cellular response to oxygen containing compoundGO:1901701790.023
ubiquitin dependent protein catabolic processGO:0006511780.023
leg disc developmentGO:0035218920.023
response to organic cyclic compoundGO:0014070890.023
connective tissue developmentGO:006144830.023
purine nucleotide metabolic processGO:00061631460.023
regulation of response to external stimulusGO:00321011150.023
tissue homeostasisGO:0001894360.023
small gtpase mediated signal transductionGO:0007264880.022
Mouse
immune system processGO:00023763470.022
purine ribonucleotide metabolic processGO:00091501450.022
negative regulation of cell developmentGO:0010721620.022
appendage morphogenesisGO:00351073970.022
regulation of wnt signaling pathwayGO:0030111680.022
aromatic compound catabolic processGO:00194391660.021
regulation of intracellular signal transductionGO:19025312360.021
Mouse
mesenchymal cell developmentGO:001403110.021
purine nucleoside metabolic processGO:00422781270.021
regulation of immune effector processGO:0002697520.021
regulation of anatomical structure sizeGO:00900661630.020
nucleobase containing small molecule metabolic processGO:00550861740.020
positive regulation of cellular component organizationGO:00511301560.020
response to alcoholGO:0097305950.020
adherens junction organizationGO:0034332270.020
positive regulation of gene expressionGO:00106282900.020
Mouse
morphogenesis of a branching structureGO:0001763450.020
regulation of cell projection organizationGO:0031344920.020
gene silencingGO:00164581380.019
positive regulation of cellular catabolic processGO:0031331950.019
positive regulation of nervous system developmentGO:0051962690.019
Mouse
heart morphogenesisGO:0003007320.019
oxoacid metabolic processGO:00434361030.019
organic cyclic compound catabolic processGO:19013611680.019
eye photoreceptor cell developmentGO:0042462810.019
regulation of hydrolase activityGO:0051336970.019
modification dependent macromolecule catabolic processGO:0043632790.019
gland developmentGO:00487321910.019
ras protein signal transductionGO:0007265880.018
purine ribonucleoside catabolic processGO:00461301120.018
regulation of endopeptidase activityGO:0052548360.018
positive regulation of cell developmentGO:0010720610.018
Mouse
neuron fate commitmentGO:0048663500.018
cardiovascular system developmentGO:0072358820.018
regulation of chromatin silencingGO:0031935360.018
actin filament based processGO:00300292200.018
anterior posterior axis specificationGO:00099481090.018
positive regulation of cellular amine metabolic processGO:003324000.018
taxisGO:00423303040.017
Mouse
cellular protein catabolic processGO:0044257830.017
positive regulation of cellular component biogenesisGO:0044089800.017
regulation of apoptotic processGO:00429811300.017
organonitrogen compound biosynthetic processGO:19015661170.017
positive regulation of developmental processGO:00510941430.017
Mouse
modification dependent protein catabolic processGO:0019941780.017
positive regulation of cellular amino acid metabolic processGO:004576400.017
response to lipidGO:0033993380.017
response to endogenous stimulusGO:00097191190.017
regulation of immune system processGO:00026821760.017
circulatory system developmentGO:0072359820.017
developmental growth involved in morphogenesisGO:0060560650.016
protein modification by small protein conjugation or removalGO:00706471060.016
proteasomal protein catabolic processGO:0010498590.016
dendrite developmentGO:00163582040.016
regulation of cellular response to stressGO:0080135890.016
metaphase anaphase transition of mitotic cell cycleGO:0007091280.016
anatomical structure homeostasisGO:0060249970.016
cell adhesionGO:00071551360.016
Rat
ribose phosphate metabolic processGO:00196931450.016
positive regulation of hydrolase activityGO:0051345780.016
ribonucleotide metabolic processGO:00092591450.016
purine ribonucleoside triphosphate metabolic processGO:00092051190.016
positive regulation of proteolysisGO:0045862520.016
negative regulation of cell differentiationGO:00455961430.016
cellular macromolecule catabolic processGO:00442651360.016
single organism biosynthetic processGO:00447112060.016
positive regulation of rho gtpase activityGO:0032321190.016
peptidyl lysine acetylationGO:0018394390.016
positive regulation of macromolecule biosynthetic processGO:00105572830.016
Mouse
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280230.015
dendrite morphogenesisGO:00488131990.015
imaginal disc derived appendage developmentGO:00487373990.015
protein complex assemblyGO:00064612000.015
determination of adult lifespanGO:00083401370.015
purine containing compound metabolic processGO:00725211550.015
rho protein signal transductionGO:0007266140.015
cell divisionGO:00513012480.015
regulation of synapse organizationGO:00508071100.015
regulation of cellular protein catabolic processGO:1903362440.015
growthGO:00400073590.014
nucleobase containing compound catabolic processGO:00346551650.014
mitotic cell cycle phase transitionGO:00447721380.014
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.014
Mouse
embryonic development via the syncytial blastodermGO:00017001480.014
regulation of protein modification processGO:00313991120.014
Mouse
cytoplasmic transportGO:00164821300.014
regulation of mitotic cell cycleGO:00073461900.014
regulation of chromosome segregationGO:0051983320.014
nucleotide metabolic processGO:00091171610.014
sensory perceptionGO:00076001960.013
positive regulation of nucleic acid templated transcriptionGO:19035082660.013
Mouse
stem cell differentiationGO:00488631170.013
negative regulation of cellular component organizationGO:00511291080.013
negative regulation of protein metabolic processGO:0051248850.013
olfactory behaviorGO:0042048970.013
epithelium migrationGO:00901321480.013
regulation of ras protein signal transductionGO:0046578930.013
response to biotic stimulusGO:00096072940.013
cell cycle phase transitionGO:00447701400.013
notch signaling pathwayGO:00072191200.013
cell cell signaling involved in cell fate commitmentGO:00451682100.013
nucleoside triphosphate metabolic processGO:00091411200.013
organic substance transportGO:00717022570.013
regulation of neurogenesisGO:00507671580.013
Mouse
response to temperature stimulusGO:00092661060.013
apoptotic processGO:00069151590.012
telencephalon developmentGO:002153720.012
Mouse
positive regulation of phosphorus metabolic processGO:00105621390.012
Mouse
regulation of neuron differentiationGO:00456641030.012
Mouse
protein catabolic processGO:00301631010.012
protein acylationGO:0043543420.012
cellular response to biotic stimulusGO:007121640.012
single organism cell adhesionGO:0098602470.012
guanosine containing compound metabolic processGO:1901068740.012
endocytosisGO:00068973100.012
response to nutrient levelsGO:00316671140.012
negative regulation of cell deathGO:0060548810.012
protein modification by small protein conjugationGO:0032446790.012
cellular response to dna damage stimulusGO:00069742230.012
intracellular signal transductionGO:00355563000.012
Mouse
protein ubiquitinationGO:0016567700.012
positive regulation of phosphorylationGO:0042327870.012
Mouse
humoral immune responseGO:00069591170.012
response to external biotic stimulusGO:00432072930.012
regulation of nucleotide catabolic processGO:0030811480.012
regulation of protein stabilityGO:0031647430.012
chemotaxisGO:00069352490.012
Mouse
regulation of mitotic sister chromatid separationGO:0010965280.012
negative regulation of cell cycle phase transitionGO:19019881030.012
embryonic pattern specificationGO:00098801740.012
cell junction assemblyGO:0034329420.012
morphogenesis of a polarized epitheliumGO:0001738930.011
regulation of rho protein signal transductionGO:0035023200.011
feeding behaviorGO:0007631500.011
dna repairGO:0006281540.011
cellular response to organic substanceGO:00713101320.011
single organism behaviorGO:00447083910.011
positive regulation of purine nucleotide metabolic processGO:1900544550.011
salivary gland developmentGO:00074311620.011
regulation of purine nucleotide catabolic processGO:0033121480.011
peptide metabolic processGO:0006518800.011
regulation of epithelial cell differentiationGO:003085640.011
positive regulation of transcription dna templatedGO:00458932660.011
Mouse
retinal cone cell differentiationGO:004267020.011
single organism intracellular transportGO:19025822070.011
regulation of behaviorGO:0050795750.011
agingGO:00075681430.011
positive regulation of nucleotide catabolic processGO:0030813460.011
mitotic sister chromatid separationGO:0051306300.011
regulation of protein localizationGO:0032880760.011
cell junction organizationGO:0034330570.011
regulation of i kappab kinase nf kappab signalingGO:004312220.011
response to bacteriumGO:00096171980.011
purine nucleoside catabolic processGO:00061521120.011
regulation of cellular localizationGO:00603411360.011
cell cell adhesionGO:0098609260.011
developmental programmed cell deathGO:00106231380.011
regulation of peptidase activityGO:0052547390.011
negative regulation of meiotic cell cycleGO:005144720.011
regulation of protein phosphorylationGO:0001932640.010
Mouse
positive regulation of rna metabolic processGO:00512542710.010
Mouse
single organismal cell cell adhesionGO:0016337450.010
negative regulation of multicellular organismal processGO:00512411420.010
purine nucleotide catabolic processGO:00061951090.010
nuclear dna replicationGO:003326010.010
regulation of stress activated mapk cascadeGO:0032872410.010
organonitrogen compound catabolic processGO:19015651280.010

iHog disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.093
cancerDOID:16200.016
organ system cancerDOID:005068600.016
disease of cellular proliferationDOID:1456600.016
sensory system diseaseDOID:005015500.010
eye and adnexa diseaseDOID:149200.010
nervous system diseaseDOID:86300.010