Drosophila melanogaster

76 known processes

Gmd (Dmel_CG8890)

GDP-mannose 4,6-dehydratase

(Aliases: CG8890,DmGMD,l(2)SH1606,l(2)SH2 1606,GMD,Dmel\CG8890,gmd,Dm-gmd)

Gmd biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
internal peptidyl lysine acetylationGO:0018393380.411
regulation of transcription from rna polymerase ii promoterGO:00063573780.407
protein acylationGO:0043543420.404
negative regulation of biosynthetic processGO:00098902770.404
positive regulation of cysteine type endopeptidase activityGO:2001056240.374
internal protein amino acid acetylationGO:0006475380.333
vesicle mediated transportGO:00161923810.321
positive regulation of cellular biosynthetic processGO:00313283160.263
histone h4 acetylationGO:0043967130.226
activation of cysteine type endopeptidase activityGO:0097202170.215
negative regulation of nitrogen compound metabolic processGO:00511722650.213
larval developmentGO:00021641040.211
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.209
regulation of small gtpase mediated signal transductionGO:0051056930.209
negative regulation of nucleic acid templated transcriptionGO:19035072400.202
regulation of cysteine type endopeptidase activityGO:2000116270.200
tube morphogenesisGO:00352391910.194
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.193
cytokinesisGO:0000910900.185
negative regulation of gene expressionGO:00106293870.184
protein acetylationGO:0006473390.175
positive regulation of macromolecule metabolic processGO:00106044050.174
regulation of histone acetylationGO:003506570.164
positive regulation of endopeptidase activityGO:0010950260.163
positive regulation of transcription dna templatedGO:00458932660.156
cellular response to dsrnaGO:0071359150.153
regulation of endopeptidase activityGO:0052548360.153
positive regulation of macromolecule biosynthetic processGO:00105572830.151
regulation of notch signaling pathwayGO:00085931000.149
establishment of localization in cellGO:00516494020.139
intracellular transportGO:00469072280.139
regulation of protein metabolic processGO:00512462560.133
histone acetylationGO:0016573380.131
negative regulation of transcription dna templatedGO:00458922370.128
peptidyl lysine acetylationGO:0018394390.126
positive regulation of cellular component organizationGO:00511301560.122
negative regulation of macromolecule biosynthetic processGO:00105582700.119
apoptotic processGO:00069151590.119
compound eye developmentGO:00487493070.117
regulation of localizationGO:00328792750.115
negative regulation of signal transductionGO:00099682060.114
regulation of golgi to plasma membrane protein transportGO:004299660.109
positive regulation of nucleic acid templated transcriptionGO:19035082660.105
regulation of cellular amino acid metabolic processGO:000652100.104
notch signaling pathwayGO:00072191200.103
positive regulation of biosynthetic processGO:00098913160.102
positive regulation of nitrogen compound metabolic processGO:00511733540.099
positive regulation of rna metabolic processGO:00512542710.099
single organism intracellular transportGO:19025822070.099
camera type eye developmentGO:004301040.097
regulation of multicellular organismal developmentGO:20000264140.090
positive regulation of transportGO:0051050920.088
meiotic cell cycle processGO:19030461320.085
regulation of cellular ketone metabolic processGO:001056530.079
epithelial cell differentiationGO:00308553220.079
carbohydrate derivative biosynthetic processGO:1901137850.077
dorsal ventral pattern formationGO:00099531330.076
negative regulation of nucleobase containing compound metabolic processGO:00459342610.074
cell proliferationGO:00082832990.072
homeostatic processGO:00425921990.069
negative regulation of developmental processGO:00510932010.069
regulation of peptidase activityGO:0052547390.068
axon developmentGO:00615642970.067
golgi to plasma membrane transportGO:000689380.067
ncrna metabolic processGO:0034660430.066
eye morphogenesisGO:00485922600.064
growthGO:00400073590.062
negative regulation of rna metabolic processGO:00512532510.061
head developmentGO:00603221350.061
regulation of phosphate metabolic processGO:00192202100.061
transcription from rna polymerase ii promoterGO:00063663680.060
negative regulation of response to stimulusGO:00485852580.060
endocytosisGO:00068973100.058
positive regulation of signal transductionGO:00099672230.058
cellular ketone metabolic processGO:0042180240.058
retina development in camera type eyeGO:006004140.056
positive regulation of catabolic processGO:00098961050.056
defense responseGO:00069523000.054
protein modification processGO:00362114380.054
regulation of cellular catabolic processGO:00313291570.054
cellular protein localizationGO:00346131600.053
regionalizationGO:00030024160.053
regulation of multi organism processGO:00439001310.053
negative regulation of cellular metabolic processGO:00313243820.052
protein catabolic processGO:00301631010.052
positive regulation of cellular component biogenesisGO:0044089800.051
single organism behaviorGO:00447083910.051
meiotic cell cycleGO:00513211710.050
oocyte fate determinationGO:0030716270.048
ncrna processingGO:0034470300.048
negative regulation of signalingGO:00230572190.048
negative regulation of apoptotic processGO:0043066630.047
positive regulation of compound eye retinal cell programmed cell deathGO:004667290.046
adult behaviorGO:00305341370.045
organic substance catabolic processGO:19015753080.045
small molecule metabolic processGO:00442813050.044
positive regulation of nucleobase containing compound metabolic processGO:00459353320.044
positive regulation of proteolysisGO:0045862520.044
eye developmentGO:00016543230.044
post golgi vesicle mediated transportGO:0006892110.043
compound eye photoreceptor developmentGO:0042051780.043
negative regulation of rna biosynthetic processGO:19026792400.042
negative regulation of organelle organizationGO:0010639560.042
posttranscriptional gene silencing by rnaGO:0035194450.042
compound eye photoreceptor cell differentiationGO:00017511400.041
negative regulation of cellular biosynthetic processGO:00313272770.040
golgi to plasma membrane protein transportGO:004300180.040
cellular macromolecule catabolic processGO:00442651360.039
mitotic cytokinesisGO:0000281500.039
appendage developmentGO:00487364010.039
cytoplasmic transportGO:00164821300.039
nuclear divisionGO:00002803320.039
chromosome segregationGO:00070591570.038
response to other organismGO:00517072930.038
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280230.038
ovarian follicle cell developmentGO:00307072480.037
regulation of cellular protein metabolic processGO:00322682430.037
regulation of intracellular signal transductionGO:19025312360.037
positive regulation of cellular protein metabolic processGO:00322701180.037
regulation of hydrolase activityGO:0051336970.036
establishment or maintenance of cell polarityGO:00071631670.035
golgi vesicle transportGO:0048193270.035
response to extracellular stimulusGO:00099911160.035
positive regulation of hydrolase activityGO:0051345780.034
positive regulation of protein metabolic processGO:00512471280.034
positive regulation of gene expressionGO:00106282900.034
regulation of nervous system developmentGO:00519602480.034
negative regulation of protein depolymerizationGO:1901880230.034
detection of stimulus involved in sensory perceptionGO:0050906920.034
response to abiotic stimulusGO:00096283410.033
dna damage checkpointGO:0000077780.033
o glycan processingGO:001626630.033
epithelial cell developmentGO:00020642740.033
cytoskeleton dependent cytokinesisGO:0061640810.033
programmed cell deathGO:00125012570.033
immune effector processGO:0002252980.032
macromolecule catabolic processGO:00090571610.031
regulation of chromatin organizationGO:1902275320.031
organelle membrane fusionGO:0090174160.031
positive regulation of rna biosynthetic processGO:19026802660.030
regulation of cellular component biogenesisGO:00440872010.030
negative regulation of nervous system developmentGO:0051961920.030
organelle fissionGO:00482853400.030
cellular response to starvationGO:0009267610.029
positive regulation of cell deathGO:0010942690.029
nucleobase containing small molecule metabolic processGO:00550861740.029
regulation of transportGO:00510491810.029
ion transmembrane transportGO:00342201220.028
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.028
eye photoreceptor cell developmentGO:0042462810.028
neurological system processGO:00508773580.027
tube developmentGO:00352952440.027
positive regulation of catalytic activityGO:00430851180.027
regulation of protein modification processGO:00313991120.027
negative regulation of developmental growthGO:0048640640.027
phagocytosisGO:00069092150.026
regulation of apoptotic processGO:00429811300.026
tissue morphogenesisGO:00487292970.026
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.026
execution phase of apoptosisGO:009719470.026
cellular catabolic processGO:00442483720.026
regulation of cellular component sizeGO:0032535980.025
determination of adult lifespanGO:00083401370.025
regulation of molecular functionGO:00650092170.025
negative regulation of cell differentiationGO:00455961430.025
female germ line cyst formationGO:0048135420.025
oocyte developmentGO:00485991240.025
imaginal disc pattern formationGO:0007447910.025
exocytosisGO:0006887280.025
negative regulation of notch signaling pathwayGO:0045746410.025
carbohydrate derivative metabolic processGO:19011352170.025
regulation of phosphorus metabolic processGO:00511742100.024
positive regulation of peptidase activityGO:0010952290.024
peptidyl lysine modificationGO:0018205570.024
positive regulation of cellular catabolic processGO:0031331950.023
regulation of actin filament depolymerizationGO:003083430.023
catabolic processGO:00090564090.023
nucleotide metabolic processGO:00091171610.023
taxisGO:00423303040.023
regulation of vesicle mediated transportGO:0060627590.022
organic cyclic compound catabolic processGO:19013611680.022
glycoprotein biosynthetic processGO:0009101410.022
anatomical structure homeostasisGO:0060249970.022
male gamete generationGO:00482322010.022
single organism biosynthetic processGO:00447112060.022
maintenance of protein location in cellGO:0032507260.022
negative regulation of cytoskeleton organizationGO:0051494300.022
response to nutrient levelsGO:00316671140.021
male meiosis cytokinesisGO:0007112260.021
negative regulation of cell deathGO:0060548810.021
regulation of anatomical structure morphogenesisGO:00226032420.021
response to external biotic stimulusGO:00432072930.021
adult locomotory behaviorGO:0008344760.021
cell deathGO:00082192790.021
histone h4 k16 acetylationGO:004398440.021
regulation of organelle organizationGO:00330431960.021
organelle assemblyGO:00709251980.021
covalent chromatin modificationGO:00165691060.021
morphogenesis of embryonic epitheliumGO:0016331940.021
regulation of immune responseGO:00507761180.021
organic substance transportGO:00717022570.021
zymogen activationGO:0031638200.021
regulation of catalytic activityGO:00507901850.020
negative regulation of cell communicationGO:00106482230.020
response to starvationGO:0042594970.020
phosphorylationGO:00163102940.020
regulation of nurse cell apoptotic processGO:004547790.020
purine nucleoside catabolic processGO:00061521120.020
epithelial cell morphogenesisGO:0003382250.020
oocyte constructionGO:00073081120.020
neural retina developmentGO:000340740.020
organonitrogen compound metabolic processGO:19015643180.020
negative regulation of cellular component organizationGO:00511291080.019
positive regulation of programmed cell deathGO:0043068620.019
germarium derived female germ line cyst formationGO:0030727420.019
columnar cuboidal epithelial cell differentiationGO:00020652560.019
deathGO:00162652840.019
hemopoiesisGO:0030097460.019
regulation of immune effector processGO:0002697520.019
digestive tract developmentGO:00485651490.019
morphogenesis of an epitheliumGO:00020092760.018
hemocyte differentiationGO:0042386380.018
trna processingGO:000803330.018
nucleobase containing compound catabolic processGO:00346551650.018
positive regulation of molecular functionGO:00440931360.018
intracellular signal transductionGO:00355563000.018
chromatin organizationGO:00063252070.018
embryo development ending in birth or egg hatchingGO:00097921520.018
multicellular organismal homeostasisGO:0048871410.017
eye antennal disc developmentGO:0035214600.017
ribonucleoside metabolic processGO:00091191270.017
actin filament based processGO:00300292200.017
defense response to other organismGO:00985422250.017
regulation of cellular amine metabolic processGO:003323830.017
immune system processGO:00023763470.017
positive regulation of apoptotic signaling pathwayGO:200123540.017
protein localizationGO:00081042840.017
negative regulation of intracellular signal transductionGO:1902532570.016
instar larval developmentGO:0002168550.016
cation transportGO:00068121100.016
stress activated protein kinase signaling cascadeGO:0031098550.016
cellular amino acid metabolic processGO:0006520610.016
determination of bilateral symmetryGO:0009855130.016
regulation of programmed cell deathGO:00430671520.016
rhabdomere developmentGO:0042052380.016
vesicle organizationGO:0016050440.016
cellular homeostasisGO:0019725800.016
single organism catabolic processGO:00447122280.016
actin filament depolymerizationGO:003004250.016
embryonic organ developmentGO:0048568500.015
negative regulation of programmed cell deathGO:0043069720.015
secretionGO:00469031090.015
sensory organ morphogenesisGO:00905962600.015
regulation of cell developmentGO:00602842150.015
cellular response to abiotic stimulusGO:0071214580.015
positive regulation of protein transportGO:0051222370.015
protein transportGO:00150311550.015
cellular protein modification processGO:00064644380.015
positive regulation of protein kinase activityGO:0045860250.015
regulation of cytoskeleton organizationGO:0051493890.015
regulation of proteolysisGO:0030162870.015
regulation of reproductive processGO:2000241540.015
regulation of catabolic processGO:00098941700.015
response to biotic stimulusGO:00096072940.015
compound eye morphogenesisGO:00017452490.015
neuromuscular synaptic transmissionGO:0007274670.015
regulation of actin filament polymerizationGO:0030833250.015
positive regulation of protein modification processGO:0031401580.014
intrinsic apoptotic signaling pathway by p53 class mediatorGO:007233250.014
detection of stimulusGO:00516061560.014
wing disc morphogenesisGO:00074723440.014
negative regulation of chromosome organizationGO:2001251190.014
tissue homeostasisGO:0001894360.014
germarium derived oocyte fate determinationGO:0007294260.014
cell cycle arrestGO:000705040.014
developmental maturationGO:00217001720.014
photoreceptor cell differentiationGO:00465301700.014
wing disc pattern formationGO:0035222660.013
response to dsrnaGO:0043331150.013
proteolysis involved in cellular protein catabolic processGO:0051603830.013
meiotic cytokinesisGO:0033206330.013
regulation of defense responseGO:00313471020.013
peptidyl amino acid modificationGO:00181931050.013
response to virusGO:0009615280.013
ribonucleoside triphosphate metabolic processGO:00091991190.013
germarium derived egg chamber formationGO:00072931010.013
regulation of cell differentiationGO:00455953020.013
cuticle developmentGO:0042335860.013
glycosyl compound metabolic processGO:19016571270.013
kidney developmentGO:000182230.013
positive regulation of secretion by cellGO:1903532200.013
nucleoside phosphate metabolic processGO:00067531620.013
positive regulation of cellular amino acid metabolic processGO:004576400.013
tissue migrationGO:00901301550.013
positive regulation of apoptotic processGO:0043065470.012
regulation of protein transportGO:0051223570.012
gastrulation with mouth forming firstGO:0001703360.012
regulation of protein localization to nucleusGO:1900180290.012
digestive system developmentGO:00551231490.012
establishment of protein localization to plasma membraneGO:009000290.012
smoothened signaling pathwayGO:0007224490.012
organophosphate catabolic processGO:00464341120.012
urogenital system developmentGO:0001655720.012
regulation of phosphorylationGO:00423251470.012
rhabdomere membrane biogenesisGO:004531360.012
cellular protein catabolic processGO:0044257830.012
actin nucleationGO:004501080.012
enzyme linked receptor protein signaling pathwayGO:00071671790.012
regulation of establishment of protein localizationGO:0070201610.012
regulation of cell proliferationGO:00421271630.012
axis elongationGO:000340130.012
positive regulation of protein complex assemblyGO:0031334220.012
cellular amine metabolic processGO:0044106120.012
positive regulation of cellular amine metabolic processGO:003324000.012
segmentationGO:00352822070.012
appendage morphogenesisGO:00351073970.012
negative regulation of small gtpase mediated signal transductionGO:0051058130.012
regulation of production of molecular mediator of immune responseGO:0002700440.012
regulation of intracellular protein transportGO:0033157460.011
positive regulation of secretionGO:0051047220.011
negative regulation of chromatin modificationGO:190330950.011
meiotic spindle organizationGO:0000212360.011
proteolysisGO:00065081920.011
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145300.011
limb developmentGO:006017310.011
purine nucleoside metabolic processGO:00422781270.011
ion transportGO:00068111450.011
nucleotide catabolic processGO:00091661090.011
cellular response to external stimulusGO:0071496660.011
extracellular matrix constituent secretionGO:007027840.011
ribonucleotide catabolic processGO:00092611090.011
regulation of protein ubiquitinationGO:0031396220.011
regulation of transferase activityGO:0051338580.011
body morphogenesisGO:001017120.011
decapentaplegic signaling pathwayGO:0008101190.011
histolysisGO:00075591020.011
axis specificationGO:00097981670.011
single organism cellular localizationGO:19025801800.010
stem cell developmentGO:0048864790.010
macromolecular complex disassemblyGO:0032984370.010
retinal cell programmed cell deathGO:0046666250.010
hematopoietic or lymphoid organ developmentGO:0048534570.010
digestive tract morphogenesisGO:00485461270.010
protein processingGO:0016485680.010
negative regulation of synaptic growth at neuromuscular junctionGO:0045886390.010
macromolecular complex assemblyGO:00650032560.010
regulation of cytoplasmic transportGO:1903649470.010
protein glycosylationGO:0006486320.010
oocyte differentiationGO:00099941450.010
purine nucleoside triphosphate catabolic processGO:00091461080.010
maintenance of protein locationGO:0045185280.010
negative regulation of protein complex disassemblyGO:0043242230.010

Gmd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.071
disease of cellular proliferationDOID:1456600.018
organ system cancerDOID:005068600.017
musculoskeletal system cancerDOID:006010000.017
cancerDOID:16200.017
connective tissue cancerDOID:20100.017