IMP: Integrative Multi-species Prediction

Drosophila melanogaster

143 known processes

acj6 (Dmel_CG9151)

abnormal chemosensory jump 6

(Aliases: Ipou,tI-POU,ACJ6,Acj6,CG9151,Dmel\CG9151,I-POU)

Entrez: 47080
FLYBASE: FBgn0000028
UniProtKB: B7Z0Y6
UniProtKB: P24350
UniProtKB: M9NDY0
UniProtKB: M9NH32
UniProtKB: M9NDX7
UniProtKB: M9NF66
UniProtKB: M9NF61
UniProtKB: M9NGG0
UniProtKB: M9NH29
UniProtKB: M9NEH8

Process Predictions
Disease Predictions

acj6 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
single organism behavior	GO:0044708	391	0.997
locomotory behavior	GO:0007626	176	0.974
chemosensory behavior	GO:0007635	106	0.932
adult behavior	GO:0030534	137	0.688
adult locomotory behavior	GO:0008344	76	0.681
detection of visible light	GO:0009584	38	0.622
multi organism behavior	GO:0051705	175	0.569	Mouse Worm
sensory perception	GO:0007600	196	0.562
sensory perception of chemical stimulus	GO:0007606	116	0.560
axonogenesis	GO:0007409	290	0.505
taxis	GO:0042330	304	0.465
neurological system process	GO:0050877	358	0.345
mating	GO:0007618	120	0.329
behavioral response to nutrient	GO:0051780	7	0.329
male mating behavior	GO:0060179	70	0.298
chemotaxis	GO:0006935	249	0.273
axon guidance	GO:0007411	233	0.271
response to light stimulus	GO:0009416	124	0.268
synaptic transmission	GO:0007268	288	0.254
response to organic substance	GO:0010033	284	0.232
response to radiation	GO:0009314	155	0.232
dendrite development	GO:0016358	204	0.231
larval behavior	GO:0030537	42	0.188
detection of stimulus	GO:0051606	156	0.174
sensory perception of mechanical stimulus	GO:0050954	72	0.170	Mouse
neuron neuron synaptic transmission	GO:0007270	14	0.162
transmembrane transport	GO:0055085	139	0.152
response to abiotic stimulus	GO:0009628	341	0.148	Worm
dendrite morphogenesis	GO:0048813	199	0.148
limb development	GO:0060173	1	0.141
response to oxygen containing compound	GO:1901700	200	0.133
neuron projection guidance	GO:0097485	241	0.128
regulation of synapse structure and activity	GO:0050803	128	0.117
multi organism reproductive behavior	GO:0044705	121	0.111	Worm
dendrite guidance	GO:0070983	21	0.108
neuron recognition	GO:0008038	101	0.106
telencephalon development	GO:0021537	2	0.105
sensory perception of sound	GO:0007605	56	0.101	Mouse
microtubule based movement	GO:0007018	51	0.097
regulation of dendrite development	GO:0050773	37	0.095	Fly
regulation of multicellular organismal development	GO:2000026	414	0.095	Mouse Fly
organic hydroxy compound metabolic process	GO:1901615	83	0.093
reproductive behavior	GO:0019098	122	0.092	Worm
male courtship behavior	GO:0008049	63	0.091
circulatory system development	GO:0072359	82	0.087	Mouse
mating behavior	GO:0007617	106	0.086
ion transmembrane transport	GO:0034220	122	0.085
ion transport	GO:0006811	145	0.082
negative regulation of gene expression	GO:0010629	387	0.079	Mouse
detection of stimulus involved in sensory perception	GO:0050906	92	0.076
regulation of circadian rhythm	GO:0042752	49	0.073
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.062
larval locomotory behavior	GO:0008345	27	0.060
cellular homeostasis	GO:0019725	80	0.059
multi multicellular organism process	GO:0044706	123	0.059	Worm
learning	GO:0007612	75	0.059
detection of external stimulus	GO:0009581	66	0.058
regulation of cell death	GO:0010941	173	0.056	Mouse
limb morphogenesis	GO:0035108	1	0.055
central nervous system development	GO:0007417	201	0.053	Zebrafish Mouse Fly
regulation of synaptic transmission	GO:0050804	69	0.053
sensory perception of smell	GO:0007608	80	0.052
vesicle mediated transport	GO:0016192	381	0.051
response to mechanical stimulus	GO:0009612	28	0.051	Worm
regulation of localization	GO:0032879	275	0.050
intracellular transport	GO:0046907	228	0.049
stem cell development	GO:0048864	79	0.046	Fly
multicellular organismal reproductive behavior	GO:0033057	110	0.045	Worm
stem cell maintenance	GO:0019827	67	0.044
detection of light stimulus	GO:0009583	58	0.044
positive regulation of cellular biosynthetic process	GO:0031328	316	0.043
metal ion transport	GO:0030001	74	0.042
regulation of cell differentiation	GO:0045595	302	0.041	Mouse Fly
regulation of anatomical structure morphogenesis	GO:0022603	242	0.041	Fly
determination of dorsal ventral asymmetry	GO:0048262	3	0.041
post embryonic appendage morphogenesis	GO:0035120	385	0.041
phototaxis	GO:0042331	21	0.040
aging	GO:0007568	143	0.040
rhodopsin mediated signaling pathway	GO:0016056	21	0.040
negative regulation of developmental process	GO:0051093	201	0.040
cation transmembrane transport	GO:0098655	88	0.038
regulation of circadian sleep wake cycle	GO:0042749	25	0.038
flight behavior	GO:0007629	26	0.038
regulation of neurogenesis	GO:0050767	158	0.037	Mouse Fly
cell projection assembly	GO:0030031	94	0.037
potassium ion transport	GO:0006813	20	0.037
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.036
regulation of dendrite morphogenesis	GO:0048814	28	0.036	Fly
cellular protein modification process	GO:0006464	438	0.036
regulation of epithelial cell proliferation	GO:0050678	4	0.035
negative regulation of response to stimulus	GO:0048585	258	0.035
neuroblast development	GO:0014019	13	0.035	Fly
establishment of localization in cell	GO:0051649	402	0.034
negative regulation of cellular metabolic process	GO:0031324	382	0.034
reflex	GO:0060004	6	0.034
cellular chemical homeostasis	GO:0055082	40	0.034
cellular amino acid metabolic process	GO:0006520	61	0.033
lipid metabolic process	GO:0006629	121	0.033
regulation of cell cycle	GO:0051726	291	0.032
regulation of protein metabolic process	GO:0051246	256	0.032
regulation of cell development	GO:0060284	215	0.032	Mouse Fly
regulation of system process	GO:0044057	36	0.031
macromolecule catabolic process	GO:0009057	161	0.031
establishment of blood brain barrier	GO:0060856	16	0.030
regulation of neuron projection development	GO:0010975	69	0.029	Fly
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.029
regulation of nervous system development	GO:0051960	248	0.028	Mouse Fly
cell recognition	GO:0008037	102	0.028
courtship behavior	GO:0007619	68	0.028
regulation of membrane potential	GO:0042391	35	0.027
positive regulation of rna biosynthetic process	GO:1902680	266	0.027
monovalent inorganic cation transport	GO:0015672	40	0.027
jump response	GO:0007630	8	0.026
nonmotile primary cilium assembly	GO:0035058	8	0.026
organic acid metabolic process	GO:0006082	103	0.026
energy taxis	GO:0009453	21	0.025
g protein coupled receptor signaling pathway	GO:0007186	136	0.025
vesicle organization	GO:0016050	44	0.025
positive regulation of peptidase activity	GO:0010952	29	0.025
wing disc pattern formation	GO:0035222	66	0.024
ventral cord development	GO:0007419	16	0.023
forebrain development	GO:0030900	2	0.023	Mouse
circadian behavior	GO:0048512	76	0.023
positive regulation of phosphorus metabolic process	GO:0010562	139	0.022
protein catabolic process	GO:0030163	101	0.022
protein phosphorylation	GO:0006468	169	0.022
olfactory behavior	GO:0042048	97	0.022
detection of chemical stimulus involved in sensory perception of smell	GO:0050911	50	0.022
phosphorylation	GO:0016310	294	0.022	Human
response to carbon dioxide	GO:0010037	4	0.022
regulation of cell projection organization	GO:0031344	92	0.022	Fly
synaptic vesicle transport	GO:0048489	50	0.021
homeostatic process	GO:0042592	199	0.021
synaptic vesicle localization	GO:0097479	53	0.021
leg disc morphogenesis	GO:0007478	80	0.021
cation homeostasis	GO:0055080	51	0.021
inorganic cation transmembrane transport	GO:0098662	61	0.021
negative regulation of neurogenesis	GO:0050768	53	0.020
negative regulation of cellular component organization	GO:0051129	108	0.020
positive regulation of gene expression	GO:0010628	290	0.020
muscle contraction	GO:0006936	13	0.020
negative regulation of nervous system development	GO:0051961	92	0.020
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.020
regulation of response to external stimulus	GO:0032101	115	0.020	Fly
regulation of programmed cell death	GO:0043067	152	0.020	Mouse
cation transport	GO:0006812	110	0.020
divalent inorganic cation homeostasis	GO:0072507	29	0.019
single organism catabolic process	GO:0044712	228	0.019
negative regulation of multicellular organismal process	GO:0051241	142	0.019
establishment of organelle localization	GO:0051656	122	0.019
cell death	GO:0008219	279	0.019	Mouse
mushroom body development	GO:0016319	70	0.019
protein complex assembly	GO:0006461	200	0.019
regulation of synapse assembly	GO:0051963	94	0.019
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.019
organonitrogen compound metabolic process	GO:1901564	318	0.019	Fly
kidney epithelium development	GO:0072073	3	0.019
chemical homeostasis	GO:0048878	92	0.019
leg disc development	GO:0035218	92	0.018
ras protein signal transduction	GO:0007265	88	0.018
oxoacid metabolic process	GO:0043436	103	0.018
transcription from rna polymerase ii promoter	GO:0006366	368	0.018
rhythmic behavior	GO:0007622	76	0.018
catabolic process	GO:0009056	409	0.018
organic substance catabolic process	GO:1901575	308	0.018
posttranscriptional regulation of gene expression	GO:0010608	145	0.018
dorsal ventral pattern formation	GO:0009953	133	0.018
regulation of phosphorus metabolic process	GO:0051174	210	0.018
axon development	GO:0061564	297	0.018
gene silencing	GO:0016458	138	0.018
positive regulation of phosphate metabolic process	GO:0045937	139	0.018
response to alcohol	GO:0097305	95	0.018
dorsal ventral pattern formation imaginal disc	GO:0007450	51	0.017
rhythmic process	GO:0048511	106	0.017
regulation of hormone levels	GO:0010817	40	0.017
small molecule metabolic process	GO:0044281	305	0.017
cellular macromolecule localization	GO:0070727	220	0.017
imaginal disc derived leg morphogenesis	GO:0007480	80	0.017
synaptic target recognition	GO:0008039	45	0.016
chaeta development	GO:0022416	97	0.016
endocytosis	GO:0006897	310	0.016
positive regulation of catalytic activity	GO:0043085	118	0.016
necrotic cell death	GO:0070265	1	0.016
mesenchymal cell development	GO:0014031	1	0.015
regulation of multi organism process	GO:0043900	131	0.015	Fly
respiratory system development	GO:0060541	213	0.015
regulation of transport	GO:0051049	181	0.015
urogenital system development	GO:0001655	72	0.015
single organism membrane organization	GO:0044802	93	0.015
central complex development	GO:0048036	9	0.015
detection of abiotic stimulus	GO:0009582	66	0.015
regulation of organ growth	GO:0046620	42	0.015
anterior posterior pattern specification	GO:0009952	136	0.015
open tracheal system development	GO:0007424	204	0.015
programmed cell death	GO:0012501	257	0.014	Mouse
positive regulation of signaling	GO:0023056	243	0.014
organelle localization	GO:0051640	148	0.014
negative regulation of cell development	GO:0010721	62	0.014
chromatin remodeling	GO:0006338	72	0.014
phenol containing compound metabolic process	GO:0018958	57	0.014
connective tissue development	GO:0061448	3	0.014
protein heterooligomerization	GO:0051291	4	0.014
membrane organization	GO:0061024	112	0.014
metal ion homeostasis	GO:0055065	44	0.014
appendage morphogenesis	GO:0035107	397	0.014
regulation of behavior	GO:0050795	75	0.014
kidney morphogenesis	GO:0060993	3	0.014
regulation of g protein coupled receptor protein signaling pathway	GO:0008277	23	0.013
response to extracellular stimulus	GO:0009991	116	0.013
cranial nerve development	GO:0021545	1	0.013	Mouse
cellular metal ion homeostasis	GO:0006875	31	0.013
regulation of cellular response to stress	GO:0080135	89	0.013
positive regulation of cgmp metabolic process	GO:0030825	1	0.013
body morphogenesis	GO:0010171	2	0.013
male courtship behavior veined wing extension	GO:0048065	22	0.013
photoreceptor cell axon guidance	GO:0072499	23	0.013
appendage development	GO:0048736	401	0.013
sensory perception of pain	GO:0019233	4	0.013
regulation of transferase activity	GO:0051338	58	0.013
single organism biosynthetic process	GO:0044711	206	0.013
carbohydrate metabolic process	GO:0005975	82	0.013
regulation of synapse organization	GO:0050807	110	0.013
organic substance transport	GO:0071702	257	0.013
cellular ion homeostasis	GO:0006873	39	0.012
negative regulation of signal transduction	GO:0009968	206	0.012
gastrulation with mouth forming first	GO:0001703	36	0.012
developmental growth	GO:0048589	280	0.012	Mouse
carboxylic acid metabolic process	GO:0019752	92	0.012
protein maturation	GO:0051604	71	0.012
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.012
spermatid nucleus elongation	GO:0007290	4	0.012
regulation of organ morphogenesis	GO:2000027	78	0.012
smoothened signaling pathway	GO:0007224	49	0.012
nephron epithelium development	GO:0072009	3	0.012
circadian sleep wake cycle sleep	GO:0050802	23	0.012
regionalization	GO:0003002	416	0.012	Fly
membrane depolarization	GO:0051899	4	0.012
response to oxidative stress	GO:0006979	86	0.012
negative regulation of developmental growth	GO:0048640	64	0.011
cellular amine metabolic process	GO:0044106	12	0.011
positive regulation of neurotransmitter transport	GO:0051590	2	0.011
receptor clustering	GO:0043113	3	0.011
negative regulation of cell death	GO:0060548	81	0.011	Mouse
head development	GO:0060322	135	0.011	Zebrafish Mouse Fly
response to pain	GO:0048265	3	0.011
synaptic growth at neuromuscular junction	GO:0051124	119	0.011
cognition	GO:0050890	141	0.011
vesicle localization	GO:0051648	55	0.011
regulation of cell cycle phase transition	GO:1901987	130	0.011
imaginal disc pattern formation	GO:0007447	91	0.011
retina development in camera type eye	GO:0060041	4	0.011	Mouse
synapse assembly	GO:0007416	143	0.011
regulation of proteolysis	GO:0030162	87	0.011
nephron tubule morphogenesis	GO:0072078	3	0.011
regulation of vesicle mediated transport	GO:0060627	59	0.011
protein modification process	GO:0036211	438	0.011
regulation of molecular function	GO:0065009	217	0.011
regulation of mitotic cell cycle	GO:0007346	190	0.011
organic cyclic compound catabolic process	GO:1901361	168	0.011
tube development	GO:0035295	244	0.011
negative regulation of synapse assembly	GO:0051964	39	0.011
anatomical structure homeostasis	GO:0060249	97	0.011
positive regulation of protein metabolic process	GO:0051247	128	0.010
embryonic pattern specification	GO:0009880	174	0.010
regulation of hydrolase activity	GO:0051336	97	0.010
peptidyl threonine modification	GO:0018210	3	0.010
brain development	GO:0007420	120	0.010	Zebrafish Mouse Fly
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.010
regulation of catalytic activity	GO:0050790	185	0.010
neural retina development	GO:0003407	4	0.010
regulation of neuron differentiation	GO:0045664	103	0.010	Fly
circadian sleep wake cycle	GO:0042745	28	0.010
developmental maturation	GO:0021700	172	0.010
protein localization	GO:0008104	284	0.010
crystal cell differentiation	GO:0042688	7	0.010
single organism carbohydrate metabolic process	GO:0044723	72	0.010
multicellular organismal aging	GO:0010259	140	0.010
startle response	GO:0001964	16	0.010

acj6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability	Func Analog Org
disease of anatomical entity	DOID:7	0.058	Human
nervous system disease	DOID:863	0.029	Human
urinary system disease	DOID:18	0.016
central nervous system disease	DOID:331	0.015
disease of cellular proliferation	DOID:14566	0.014
cancer	DOID:162	0.012

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