Drosophila melanogaster

99 known processes

HGTX (Dmel_CG13475)

CG13475 gene product from transcript CG13475-RB

(Aliases: Nkx6,CG4745,dNkx6,CG13475,nkx6,Dmel\CG13475,Nk6)

HGTX biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
motor neuron axon guidanceGO:0008045580.999
neuron projection guidanceGO:00974852410.997
axon guidanceGO:00074112330.991
axon developmentGO:00615642970.990
chemotaxisGO:00069352490.982
taxisGO:00423303040.978
axonogenesisGO:00074092900.975
negative regulation of transcription dna templatedGO:00458922370.880
negative regulation of nucleobase containing compound metabolic processGO:00459342610.794
negative regulation of biosynthetic processGO:00098902770.767
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.760
spinal cord developmentGO:002151010.743
negative regulation of rna metabolic processGO:00512532510.739
central nervous system developmentGO:00074172010.734
neuron recognitionGO:00080381010.696
negative regulation of rna biosynthetic processGO:19026792400.696
regulation of nervous system developmentGO:00519602480.648
negative regulation of gene expressionGO:00106293870.625
regulation of neurogenesisGO:00507671580.610
negative regulation of nucleic acid templated transcriptionGO:19035072400.603
negative regulation of macromolecule biosynthetic processGO:00105582700.595
multicellular organismal reproductive behaviorGO:00330571100.584
negative regulation of nitrogen compound metabolic processGO:00511722650.574
cell recognitionGO:00080371020.552
dendrite guidanceGO:0070983210.546
neuron fate commitmentGO:0048663500.542
positive regulation of nucleic acid templated transcriptionGO:19035082660.524
neuron fate specificationGO:0048665120.502
dendrite developmentGO:00163582040.502
regulation of neuron differentiationGO:00456641030.499
synaptic transmissionGO:00072682880.473
transcription from rna polymerase ii promoterGO:00063663680.471
myoblast proliferationGO:005145030.467
positive regulation of transcription dna templatedGO:00458932660.464
dendrite morphogenesisGO:00488131990.462
negative regulation of cellular biosynthetic processGO:00313272770.403
negative regulation of cellular metabolic processGO:00313243820.403
tissue morphogenesisGO:00487292970.397
negative regulation of nervous system developmentGO:0051961920.395
reproductive behaviorGO:00190981220.395
cell migrationGO:00164772380.368
cell motilityGO:00488702510.357
regulation of cell differentiationGO:00455953020.348
positive regulation of cellular biosynthetic processGO:00313283160.327
negative regulation of neurogenesisGO:0050768530.309
regulation of multicellular organismal developmentGO:20000264140.289
muscle structure developmentGO:00610612240.282
exocrine system developmentGO:00352721620.277
multi organism reproductive behaviorGO:00447051210.275
positive regulation of macromolecule metabolic processGO:00106044050.274
negative regulation of developmental growthGO:0048640640.268
muscle organ developmentGO:00075171270.261
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.260
regulation of axon extension involved in axon guidanceGO:004884140.253
synaptic target recognitionGO:0008039450.251
regulation of dendrite morphogenesisGO:0048814280.250
localization of cellGO:00516742570.250
axon choice point recognitionGO:0016198260.248
multi multicellular organism processGO:00447061230.245
circulatory system developmentGO:0072359820.233
telencephalon developmentGO:002153720.231
positive regulation of gene expressionGO:00106282900.231
imaginal disc derived leg morphogenesisGO:0007480800.226
Fly
regulation of axon guidanceGO:1902667100.226
cell cell signaling involved in cell fate commitmentGO:00451682100.225
stem cell differentiationGO:00488631170.214
regulation of cell developmentGO:00602842150.208
positive regulation of rna biosynthetic processGO:19026802660.195
central nervous system neuron differentiationGO:002195380.195
salivary gland developmentGO:00074311620.181
forebrain developmentGO:003090020.178
body morphogenesisGO:001017120.175
negative regulation of multicellular organismal processGO:00512411420.173
regulation of cell fate commitmentGO:0010453290.173
cellular protein modification processGO:00064644380.162
chromatin remodelingGO:0006338720.152
peripheral nervous system developmentGO:0007422520.148
sensory perception of smellGO:0007608800.147
negative regulation of growthGO:0045926840.146
positive regulation of nitrogen compound metabolic processGO:00511733540.144
cell proliferationGO:00082832990.143
eye morphogenesisGO:00485922600.141
positive regulation of biosynthetic processGO:00098913160.134
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.130
regulation of cell proliferationGO:00421271630.128
axon midline choice point recognitionGO:0016199260.127
protein modification processGO:00362114380.125
regulation of axonogenesisGO:0050770320.125
multi organism behaviorGO:00517051750.123
regulation of anatomical structure morphogenesisGO:00226032420.117
neuroblast differentiationGO:0014016290.116
muscle tissue morphogenesisGO:006041520.114
regulation of transcription from rna polymerase ii promoterGO:00063573780.114
ameboidal type cell migrationGO:00016671510.113
leg disc developmentGO:0035218920.113
Fly
skeletal muscle organ developmentGO:0060538480.112
embryo development ending in birth or egg hatchingGO:00097921520.110
brain developmentGO:00074201200.110
lateral inhibitionGO:00463312060.108
regulation of cell morphogenesisGO:00226041630.107
detection of chemical stimulusGO:0009593930.107
positive regulation of response to stimulusGO:00485843230.105
Fly
regulation of neuron projection developmentGO:0010975690.105
sensory perception of chemical stimulusGO:00076061160.102
negative regulation of developmental processGO:00510932010.102
cell fate specificationGO:0001708710.100
regulation of cell morphogenesis involved in differentiationGO:0010769610.100
cell growthGO:00160491080.098
synapse assemblyGO:00074161430.094
growthGO:00400073590.092
Fly
developmental growthGO:00485892800.092
Fly
skeletal muscle tissue developmentGO:0007519130.091
gland morphogenesisGO:00226121450.085
cilium organizationGO:0044782410.084
periodic partitioningGO:0007365290.083
cell fate determinationGO:0001709910.082
positive regulation of nervous system developmentGO:0051962690.082
gland developmentGO:00487321910.081
retinal ganglion cell axon guidanceGO:0031290120.079
regulation of cell growthGO:0001558430.079
positive regulation of rna metabolic processGO:00512542710.077
compound eye photoreceptor cell differentiationGO:00017511400.074
apoptotic processGO:00069151590.073
camera type eye developmentGO:004301040.071
connective tissue developmentGO:006144830.070
regulation of apoptotic processGO:00429811300.067
salivary gland morphogenesisGO:00074351450.067
regulation of antimicrobial peptide productionGO:0002784440.067
regionalizationGO:00030024160.067
detection of chemical stimulus involved in sensory perceptionGO:0050907750.066
regulation of synaptic transmissionGO:0050804690.066
positive regulation of neurogenesisGO:0050769410.065
regulation of protein modification processGO:00313991120.063
neuron migrationGO:000176450.063
regulation of growthGO:00400082330.063
blastoderm segmentationGO:00073501590.062
stem cell developmentGO:0048864790.058
negative regulation of axon extensionGO:003051730.058
response to external biotic stimulusGO:00432072930.057
sensory organ morphogenesisGO:00905962600.055
development of primary sexual characteristicsGO:0045137500.054
regulation of synapse structure and activityGO:00508031280.053
positive regulation of cell differentiationGO:0045597640.053
chaeta developmentGO:0022416970.051
Fly
nucleobase containing small molecule metabolic processGO:00550861740.051
histone methylationGO:0016571400.050
photoreceptor cell axon guidanceGO:0072499230.050
striated muscle tissue developmentGO:0014706270.049
cardiovascular system developmentGO:0072358820.049
regulation of response to external stimulusGO:00321011150.048
regulation of cellular protein metabolic processGO:00322682430.047
larval developmentGO:00021641040.046
heart developmentGO:0007507820.046
regulation of axon extensionGO:003051680.046
regulation of vesicle mediated transportGO:0060627590.045
regulation of protein metabolic processGO:00512462560.044
eye developmentGO:00016543230.044
neuron deathGO:0070997270.044
negative regulation of response to stimulusGO:00485852580.044
segment polarity determinationGO:0007367250.043
epithelial tube morphogenesisGO:0060562880.042
neuron fate determinationGO:004866410.042
positive regulation of nucleobase containing compound metabolic processGO:00459353320.041
cell junction organizationGO:0034330570.041
organonitrogen compound metabolic processGO:19015643180.040
negative regulation of neuron differentiationGO:0045665160.039
positive regulation of transportGO:0051050920.039
negative regulation of cell communicationGO:00106482230.037
camera type eye morphogenesisGO:004859320.036
negative regulation of cell developmentGO:0010721620.036
epithelial cell differentiationGO:00308553220.036
negative regulation of cell differentiationGO:00455961430.036
tube developmentGO:00352952440.036
axon extensionGO:0048675320.035
neuroblast developmentGO:0014019130.035
histone modificationGO:00165701060.034
segmentationGO:00352822070.034
regulation of cell sizeGO:0008361630.034
respiratory system developmentGO:00605412130.033
regulation of extent of cell growthGO:006138780.033
regulation of transportGO:00510491810.033
wound healingGO:0042060750.033
response to organic substanceGO:00100332840.033
regulation of cellular component sizeGO:0032535980.033
endocytosisGO:00068973100.032
negative regulation of signal transductionGO:00099682060.032
retina morphogenesis in camera type eyeGO:006004220.032
mesenchymal cell developmentGO:001403110.031
cell maturationGO:00484691440.031
axonal defasciculationGO:0007414120.031
axon target recognitionGO:0007412160.030
detection of chemical stimulus involved in sensory perception of smellGO:0050911500.030
detection of stimulus involved in sensory perceptionGO:0050906920.030
embryonic heart tube developmentGO:0035050220.030
heart morphogenesisGO:0003007320.030
regulation of synapse assemblyGO:0051963940.029
response to woundingGO:0009611940.029
cell deathGO:00082192790.029
organonitrogen compound biosynthetic processGO:19015661170.028
muscle tissue developmentGO:0060537300.028
columnar cuboidal epithelial cell differentiationGO:00020652560.028
deathGO:00162652840.028
regulation of neuron apoptotic processGO:0043523160.028
cardiocyte differentiationGO:0035051290.027
organelle assemblyGO:00709251980.027
stem cell proliferationGO:0072089880.027
positive regulation of macromolecule biosynthetic processGO:00105572830.027
synapse organizationGO:00508081960.027
developmental pigmentationGO:0048066680.027
establishment of localization in cellGO:00516494020.026
purine ribonucleotide catabolic processGO:00091541090.026
eye photoreceptor cell differentiationGO:00017541450.026
detection of stimulusGO:00516061560.026
protein alkylationGO:0008213430.026
embryonic organ developmentGO:0048568500.026
neuroepithelial cell differentiationGO:006056360.026
axon extension involved in axon guidanceGO:0048846100.026
formation of anatomical boundaryGO:0048859370.026
methylationGO:0032259470.025
ovipositionGO:0018991190.025
negative regulation of cellular component organizationGO:00511291080.025
chromatin modificationGO:00165681470.025
regulation of cell cycleGO:00517262910.025
Fly
neuroblast proliferationGO:0007405740.025
male gamete generationGO:00482322010.024
regulation of organelle organizationGO:00330431960.024
positive regulation of axonogenesisGO:005077220.024
head developmentGO:00603221350.024
reproductive structure developmentGO:0048608740.024
regulation of localizationGO:00328792750.023
developmental cell growthGO:0048588520.023
regulation of neuron deathGO:1901214260.023
neuron projection extensionGO:1990138320.023
positive regulation of multi organism processGO:0043902400.022
regulation of developmental growthGO:00486381740.022
regulation of catalytic activityGO:00507901850.022
nucleotide metabolic processGO:00091171610.022
skin developmentGO:0043588650.022
membrane organizationGO:00610241120.022
morphogenesis of an epitheliumGO:00020092760.022
regulation of neural precursor cell proliferationGO:2000177350.022
negative regulation of signalingGO:00230572190.021
regulation of behaviorGO:0050795750.021
positive regulation of cellular protein metabolic processGO:00322701180.021
neurological system processGO:00508773580.021
ras protein signal transductionGO:0007265880.021
single organism membrane fusionGO:0044801420.021
chromatin organizationGO:00063252070.021
dna metabolic processGO:00062592270.021
single organism cell adhesionGO:0098602470.021
embryonic pattern specificationGO:00098801740.021
cardiac cell fate commitmentGO:0060911170.020
sensory perceptionGO:00076001960.020
regulation of dendrite developmentGO:0050773370.020
peptide metabolic processGO:0006518800.020
regulation of cell deathGO:00109411730.020
intracellular transportGO:00469072280.020
carbohydrate derivative metabolic processGO:19011352170.020
regulation of histone modificationGO:0031056200.019
regulation of molecular functionGO:00650092170.019
positive regulation of neuron differentiationGO:0045666260.019
positive regulation of cell proliferationGO:0008284470.019
regulation of small gtpase mediated signal transductionGO:0051056930.019
catabolic processGO:00090564090.019
hindgut developmentGO:0061525580.018
carboxylic acid metabolic processGO:0019752920.018
gonad developmentGO:0008406500.018
positive regulation of catalytic activityGO:00430851180.018
negative regulation of synapse assemblyGO:0051964390.018
cardioblast differentiationGO:0010002200.018
immune system developmentGO:0002520570.018
positive regulation of cellular component organizationGO:00511301560.018
purine ribonucleoside catabolic processGO:00461301120.018
glial cell differentiationGO:0010001350.018
negative regulation of cell deathGO:0060548810.017
phosphorylationGO:00163102940.017
purine nucleoside catabolic processGO:00061521120.017
regulation of chromatin modificationGO:1903308280.017
inositol lipid mediated signalingGO:004801740.017
response to oxygen containing compoundGO:19017002000.017
positive regulation of antimicrobial peptide productionGO:0002225280.017
regulation of cell projection organizationGO:0031344920.017
biological adhesionGO:00226101380.016
establishment of protein localizationGO:00451841630.016
organic substance catabolic processGO:19015753080.016
regulation of cell shapeGO:00083601130.016
developmental growth involved in morphogenesisGO:0060560650.016
Fly
neuroblast fate determinationGO:0007400120.016
olfactory bulb axon guidanceGO:007167830.016
regulation of notch signaling pathwayGO:00085931000.016
Fly
neuron apoptotic processGO:0051402170.016
regulation of cellular component biogenesisGO:00440872010.016
regulation of neuronal synaptic plasticityGO:004816880.016
formation of organ boundaryGO:0010160300.015
regulation of response to biotic stimulusGO:0002831630.015
positive regulation of protein metabolic processGO:00512471280.015
appendage developmentGO:00487364010.015
Fly
regulation of synaptic plasticityGO:0048167140.015
rna localizationGO:00064031150.015
gliogenesisGO:0042063800.015
vesicle organizationGO:0016050440.014
cellular protein localizationGO:00346131600.014
ribonucleotide catabolic processGO:00092611090.014
small gtpase mediated signal transductionGO:0007264880.014
single organism biosynthetic processGO:00447112060.014
cardioblast cell fate commitmentGO:0042684140.014
glycosyl compound catabolic processGO:19016581120.014
positive regulation of protein modification processGO:0031401580.014
oocyte differentiationGO:00099941450.014
ribonucleoside metabolic processGO:00091191270.014
regulation of mitotic cell cycleGO:00073461900.014
embryonic development via the syncytial blastodermGO:00017001480.014
developmental maturationGO:00217001720.013
negative regulation of sequestering of calcium ionGO:005128320.013
neural precursor cell proliferationGO:0061351750.013
positive regulation of programmed cell deathGO:0043068620.013
synaptic growth at neuromuscular junctionGO:00511241190.013
covalent chromatin modificationGO:00165691060.013
phagocytosisGO:00069092150.013
neuroblast fate commitmentGO:0014017190.013
rho protein signal transductionGO:0007266140.013
lamellipodium organizationGO:0097581210.013
regulation of antimicrobial humoral responseGO:0002759500.013
nucleoside triphosphate metabolic processGO:00091411200.013
chaeta morphogenesisGO:0008407420.013
positive regulation of developmental processGO:00510941430.013
ribonucleoside triphosphate metabolic processGO:00091991190.013
nucleobase containing compound catabolic processGO:00346551650.013
germ cell migrationGO:0008354430.013
ectodermal placode developmentGO:007169640.013
regulation of humoral immune responseGO:0002920510.013
purine nucleoside triphosphate metabolic processGO:00091441190.013
central nervous system neuron developmentGO:002195480.013
antimicrobial peptide biosynthetic processGO:0002777380.013
production of molecular mediator of immune responseGO:0002440460.013
heterocycle catabolic processGO:00467001660.012
guanosine containing compound metabolic processGO:1901068740.012
purine nucleoside triphosphate catabolic processGO:00091461080.012
protein methylationGO:0006479430.012
adult locomotory behaviorGO:0008344760.012
vesicle mediated transportGO:00161923810.012
purine ribonucleoside triphosphate metabolic processGO:00092051190.012
carbohydrate metabolic processGO:0005975820.012
cell type specific apoptotic processGO:0097285380.012
compound eye morphogenesisGO:00017452490.012
intracellular mrna localization involved in pattern specification processGO:0060810560.012
digestive system developmentGO:00551231490.012
oocyte developmentGO:00485991240.012
regulation of catabolic processGO:00098941700.012
epidermis developmentGO:0008544650.011
regulation of nucleoside metabolic processGO:0009118500.011
regulation of chromatin organizationGO:1902275320.011
regulation of phosphorus metabolic processGO:00511742100.011
locomotory behaviorGO:00076261760.011
salivary gland cell autophagic cell deathGO:0035071830.011
organophosphate metabolic processGO:00196371950.011
carbohydrate derivative catabolic processGO:19011361180.011
purine ribonucleoside metabolic processGO:00461281270.011
pyridine nucleotide metabolic processGO:001936220.011
muscle cell differentiationGO:00426921030.011
single organism membrane organizationGO:0044802930.011
purine ribonucleotide metabolic processGO:00091501450.011
posttranscriptional regulation of gene expressionGO:00106081450.011
cell cell adhesionGO:0098609260.011
establishment of planar polarityGO:0001736870.011
antimicrobial humoral responseGO:0019730990.011
developmental programmed cell deathGO:00106231380.011
cell projection assemblyGO:0030031940.011
negative regulation of programmed cell deathGO:0043069720.011
ribose phosphate metabolic processGO:00196931450.011
glycosyl compound metabolic processGO:19016571270.011
ribonucleoside catabolic processGO:00424541120.011
negative chemotaxisGO:0050919150.011
positive regulation of organelle organizationGO:0010638650.010
purine nucleotide catabolic processGO:00061951090.010
chemosensory behaviorGO:00076351060.010
positive regulation of cell deathGO:0010942690.010
amine metabolic processGO:0009308120.010
imaginal disc derived appendage morphogenesisGO:00351143950.010
Fly
cellular homeostasisGO:0019725800.010
notch signaling pathwayGO:00072191200.010
Fly
negative regulation of cell cycleGO:00457861160.010
regulation of cell cycle processGO:00105641810.010
cell cycle dna replicationGO:0044786230.010

HGTX disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
waardenburg s syndromeDOID:925800.116
cancerDOID:16200.057
disease of cellular proliferationDOID:1456600.057
organ system cancerDOID:005068600.038
disease of anatomical entityDOID:700.017