Drosophila melanogaster

0 known processes

mthl3 (Dmel_CG6530)

methuselah-like 3

(Aliases: GENE 1,anon-WO0170980.52,CG6530,anon-WO0170980.53,Mth-3,Dmel\CG6530,104/8,BEST:GM02553,l(2)k10408,gene 1)

mthl3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to organic substanceGO:00100332840.076
Fly
post embryonic appendage morphogenesisGO:00351203850.073
Fly
imaginal disc derived wing morphogenesisGO:00074763370.071
Fly
appendage developmentGO:00487364010.071
Fly
imaginal disc derived appendage developmentGO:00487373990.059
Fly
imaginal disc derived appendage morphogenesisGO:00351143950.055
Fly
establishment of localization in cellGO:00516494020.044
Fly
regulation of cell cycleGO:00517262910.042
tube developmentGO:00352952440.041
Fly
wing disc morphogenesisGO:00074723440.041
Fly
organelle fissionGO:00482853400.039
vesicle mediated transportGO:00161923810.036
Fly
tissue migrationGO:00901301550.036
Fly
nuclear divisionGO:00002803320.036
tissue morphogenesisGO:00487292970.036
Fly
organonitrogen compound metabolic processGO:19015643180.035
small molecule metabolic processGO:00442813050.035
catabolic processGO:00090564090.035
organic substance catabolic processGO:19015753080.035
response to nutrient levelsGO:00316671140.034
Fly
single organism biosynthetic processGO:00447112060.034
response to paraquatGO:190156240.034
Fly
appendage morphogenesisGO:00351073970.033
Fly
mesoderm developmentGO:0007498780.033
Fly
heterocycle catabolic processGO:00467001660.033
tube morphogenesisGO:00352391910.032
Fly
digestive tract developmentGO:00485651490.031
Fly
cellular protein modification processGO:00064644380.031
response to oxygen containing compoundGO:19017002000.031
Fly
protein modification processGO:00362114380.031
cell migrationGO:00164772380.030
organophosphate metabolic processGO:00196371950.030
single organism catabolic processGO:00447122280.030
carbohydrate derivative metabolic processGO:19011352170.029
localization of cellGO:00516742570.029
secretionGO:00469031090.029
Fly
ion transportGO:00068111450.029
secretion by cellGO:00329401010.029
Fly
agingGO:00075681430.028
Fly
nucleoside phosphate metabolic processGO:00067531620.028
organic cyclic compound catabolic processGO:19013611680.028
intracellular signal transductionGO:00355563000.028
regulation of intracellular signal transductionGO:19025312360.028
organic substance transportGO:00717022570.028
actin mediated cell contractionGO:0070252210.028
Fly
deathGO:00162652840.028
positive regulation of nucleobase containing compound metabolic processGO:00459353320.027
nucleobase containing small molecule metabolic processGO:00550861740.027
actin filament based movementGO:0030048260.027
Fly
programmed cell deathGO:00125012570.026
positive regulation of cell communicationGO:00106472500.026
aromatic compound catabolic processGO:00194391660.026
cell motilityGO:00488702510.026
positive regulation of macromolecule biosynthetic processGO:00105572830.026
cellular catabolic processGO:00442483720.026
positive regulation of cellular biosynthetic processGO:00313283160.025
regulation of catalytic activityGO:00507901850.025
cellular nitrogen compound catabolic processGO:00442701650.025
cellular response to dna damage stimulusGO:00069742230.025
positive regulation of nitrogen compound metabolic processGO:00511733540.025
establishment of organelle localizationGO:00516561220.025
Fly
positive regulation of biosynthetic processGO:00098913160.025
nucleoside phosphate catabolic processGO:19012921100.024
positive regulation of signalingGO:00230562430.024
taxisGO:00423303040.024
macromolecule catabolic processGO:00090571610.024
forebrain developmentGO:003090020.024
determination of adult lifespanGO:00083401370.024
Fly
small gtpase mediated signal transductionGO:0007264880.024
phosphorylationGO:00163102940.024
digestive system developmentGO:00551231490.024
Fly
regulation of cell cycle processGO:00105641810.024
sensory organ morphogenesisGO:00905962600.024
central nervous system developmentGO:00074172010.023
positive regulation of response to stimulusGO:00485843230.023
body morphogenesisGO:001017120.023
ras protein signal transductionGO:0007265880.023
negative regulation of gene expressionGO:00106293870.022
transcription from rna polymerase ii promoterGO:00063663680.022
response to oxidative stressGO:0006979860.022
Fly
ribonucleotide metabolic processGO:00092591450.022
immune responseGO:00069552460.022
response to abiotic stimulusGO:00096283410.022
Fly
salivary gland morphogenesisGO:00074351450.022
digestive tract morphogenesisGO:00485461270.022
Fly
response to organophosphorusGO:004668320.022
regulation of phosphate metabolic processGO:00192202100.022
purine containing compound metabolic processGO:00725211550.022
positive regulation of macromolecule metabolic processGO:00106044050.022
ameboidal type cell migrationGO:00016671510.022
regulation of multicellular organismal developmentGO:20000264140.022
regulation of molecular functionGO:00650092170.021
response to heatGO:0009408630.021
Fly
homeostatic processGO:00425921990.021
regulation of phosphorus metabolic processGO:00511742100.021
axonogenesisGO:00074092900.021
nucleotide metabolic processGO:00091171610.021
cell proliferationGO:00082832990.021
cell deathGO:00082192790.021
eye morphogenesisGO:00485922600.021
axon developmentGO:00615642970.021
protein complex biogenesisGO:00702712010.021
protein localizationGO:00081042840.021
intracellular transportGO:00469072280.021
ion transmembrane transportGO:00342201220.021
negative regulation of cell cycle processGO:00109481090.021
nucleobase containing compound catabolic processGO:00346551650.021
chromosome segregationGO:00070591570.021
establishment of synaptic vesicle localizationGO:0097480500.020
Fly
compound eye morphogenesisGO:00017452490.020
telencephalon developmentGO:002153720.020
regulation of localizationGO:00328792750.020
exocrine system developmentGO:00352721620.020
positive regulation of cell motilityGO:200014730.020
gland morphogenesisGO:00226121450.020
regulation of organelle organizationGO:00330431960.020
eye developmentGO:00016543230.020
adult behaviorGO:00305341370.020
single organism behaviorGO:00447083910.020
positive regulation of signal transductionGO:00099672230.020
negative regulation of cell communicationGO:00106482230.020
regulation of catabolic processGO:00098941700.020
positive regulation of phosphate metabolic processGO:00459371390.019
negative regulation of response to stimulusGO:00485852580.019
actin filament based processGO:00300292200.019
Fly
negative regulation of nitrogen compound metabolic processGO:00511722650.019
neurological system processGO:00508773580.019
compound eye developmentGO:00487493070.019
response to lipopolysaccharideGO:003249640.019
positive regulation of catalytic activityGO:00430851180.019
spindle organizationGO:00070512530.019
purine containing compound catabolic processGO:00725231120.019
embryonic morphogenesisGO:00485982060.019
Fly
regulation of programmed cell deathGO:00430671520.019
macromolecular complex assemblyGO:00650032560.019
positive regulation of cell migrationGO:003033520.019
oxoacid metabolic processGO:00434361030.019
response to temperature stimulusGO:00092661060.019
Fly
cellularizationGO:0007349900.019
cation transportGO:00068121100.018
regulation of cellular catabolic processGO:00313291570.018
carbohydrate derivative catabolic processGO:19011361180.018
organonitrogen compound catabolic processGO:19015651280.018
negative regulation of cellular metabolic processGO:00313243820.018
negative regulation of signalingGO:00230572190.018
response to extracellular stimulusGO:00099911160.018
Fly
salivary gland developmentGO:00074311620.018
phagocytosisGO:00069092150.018
response to starvationGO:0042594970.018
Fly
negative regulation of signal transductionGO:00099682060.018
protein complex assemblyGO:00064612000.018
cell cell signaling involved in cell fate commitmentGO:00451682100.018
camera type eye developmentGO:004301040.018
negative regulation of developmental processGO:00510932010.018
positive regulation of phosphorus metabolic processGO:00105621390.018
vesicle localizationGO:0051648550.018
Fly
purine ribonucleotide metabolic processGO:00091501450.018
kidney developmentGO:000182230.018
purine nucleoside catabolic processGO:00061521120.018
response to other organismGO:00517072930.018
purine nucleotide metabolic processGO:00061631460.018
protein transportGO:00150311550.018
glycosyl compound metabolic processGO:19016571270.018
immune system processGO:00023763470.018
chaeta developmentGO:0022416970.017
connective tissue developmentGO:006144830.017
gland developmentGO:00487321910.017
nucleoside catabolic processGO:00091641120.017
purine ribonucleotide catabolic processGO:00091541090.017
protein phosphorylationGO:00064681690.017
chemotaxisGO:00069352490.017
mitotic nuclear divisionGO:00070672130.017
regulation of cellular ketone metabolic processGO:001056530.017
steroid catabolic processGO:000670610.017
positive regulation of rna biosynthetic processGO:19026802660.017
cell projection assemblyGO:0030031940.017
cellular response to chemical stimulusGO:00708871990.017
centrosome organizationGO:00512971630.017
defense responseGO:00069523000.017
ribonucleoside triphosphate catabolic processGO:00092031080.017
columnar cuboidal epithelial cell developmentGO:00020662490.017
cellular homeostasisGO:0019725800.017
negative regulation of biosynthetic processGO:00098902770.017
mrna metabolic processGO:00160711240.017
response to organic cyclic compoundGO:0014070890.017
pigment metabolic processGO:0042440840.017
purine ribonucleoside triphosphate catabolic processGO:00092071080.017
cellular macromolecule catabolic processGO:00442651360.016
neuron projection guidanceGO:00974852410.016
purine nucleoside metabolic processGO:00422781270.016
chromosome organizationGO:00512763600.016
nucleoside metabolic processGO:00091161270.016
response to reactive oxygen speciesGO:0000302240.016
Fly
negative regulation of macromolecule biosynthetic processGO:00105582700.016
purine ribonucleoside triphosphate metabolic processGO:00092051190.016
carboxylic acid metabolic processGO:0019752920.016
chromatin organizationGO:00063252070.016
establishment of protein localizationGO:00451841630.016
glycosyl compound catabolic processGO:19016581120.016
organophosphate catabolic processGO:00464341120.016
multi multicellular organism processGO:00447061230.016
nucleotide catabolic processGO:00091661090.016
ribose phosphate metabolic processGO:00196931450.016
ribonucleoside metabolic processGO:00091191270.016
regulation of cellular amine metabolic processGO:003323830.016
regulation of response to stressGO:00801342000.016
mitotic dna integrity checkpointGO:0044774750.016
regulation of cell proliferationGO:00421271630.016
regulation of immune system processGO:00026821760.016
synaptic vesicle localizationGO:0097479530.016
Fly
purine ribonucleoside catabolic processGO:00461301120.016
dna metabolic processGO:00062592270.016
respiratory system developmentGO:00605412130.015
negative regulation of nucleobase containing compound metabolic processGO:00459342610.015
inorganic ion transmembrane transportGO:0098660730.015
endocytosisGO:00068973100.015
regulation of protein metabolic processGO:00512462560.015
cellular response to organic substanceGO:00713101320.015
negative regulation of cellular biosynthetic processGO:00313272770.015
regulation of cellular component biogenesisGO:00440872010.015
transmembrane transportGO:00550851390.015
histolysisGO:00075591020.015
negative regulation of rna metabolic processGO:00512532510.015
androgen metabolic processGO:000820910.015
rna localizationGO:00064031150.015
g protein coupled receptor signaling pathwayGO:00071861360.015
Fly
response to endogenous stimulusGO:00097191190.015
regulation of ras protein signal transductionGO:0046578930.015
purine ribonucleoside metabolic processGO:00461281270.015
dna damage checkpointGO:0000077780.015
nucleoside triphosphate catabolic processGO:00091431080.015
ribonucleoside triphosphate metabolic processGO:00091991190.015
organonitrogen compound biosynthetic processGO:19015661170.015
nucleoside triphosphate metabolic processGO:00091411200.015
regulation of mitotic cell cycleGO:00073461900.015
guanosine containing compound metabolic processGO:1901068740.015
ribonucleoside catabolic processGO:00424541120.015
microtubule organizing center organizationGO:00310231680.015
positive regulation of catabolic processGO:00098961050.015
ribonucleotide catabolic processGO:00092611090.015
matingGO:00076181200.014
regulation of cell cycle phase transitionGO:19019871300.014
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.014
response to glucoseGO:000974920.014
developmental programmed cell deathGO:00106231380.014
cell cycle checkpointGO:0000075950.014
axon guidanceGO:00074112330.014
cell divisionGO:00513012480.014
multicellular organismal agingGO:00102591400.014
Fly
gene silencingGO:00164581380.014
organelle assemblyGO:00709251980.014
innate immune responseGO:00450871440.014
growthGO:00400073590.014
regulation of cellular protein metabolic processGO:00322682430.014
regulation of cell deathGO:00109411730.014
reproductive behaviorGO:00190981220.014
developmental maturationGO:00217001720.014
nephron developmentGO:007200630.014
sensory perceptionGO:00076001960.014
positive regulation of intracellular signal transductionGO:19025331160.014
amine metabolic processGO:0009308120.014
purine nucleotide catabolic processGO:00061951090.014
epithelial cell differentiationGO:00308553220.014
g2 dna damage checkpointGO:0031572690.014
germarium derived egg chamber formationGO:00072931010.014
purine nucleoside triphosphate catabolic processGO:00091461080.014
regulation of cell differentiationGO:00455953020.014
proteolysisGO:00065081920.014
mrna processingGO:00063971040.014
wnt signaling pathwayGO:0016055980.014
purine nucleoside triphosphate metabolic processGO:00091441190.014
regionalizationGO:00030024160.014
developmental growthGO:00485892800.014
defense response to other organismGO:00985422250.014
gtp catabolic processGO:0006184720.014
cellular amino acid metabolic processGO:0006520610.014
morphogenesis of an epitheliumGO:00020092760.014
mitotic cell cycle checkpointGO:0007093880.014
regulation of cellular amino acid metabolic processGO:000652100.014
organelle localizationGO:00516401480.014
Fly
organic acid metabolic processGO:00060821030.014
regulation of transportGO:00510491810.013
mitotic spindle organizationGO:00070522200.013
regulation of mitotic cell cycle phase transitionGO:19019901300.013
gtp metabolic processGO:0046039720.013
mitotic g2 m transition checkpointGO:0044818700.013
positive regulation of gene expressionGO:00106282900.013
regulation of small gtpase mediated signal transductionGO:0051056930.013
immune response regulating signaling pathwayGO:000276420.013
positive regulation of nucleic acid templated transcriptionGO:19035082660.013
cytoplasmic transportGO:00164821300.013
synaptic transmissionGO:00072682880.013
Fly
open tracheal system developmentGO:00074242040.013
cellular amine metabolic processGO:0044106120.013
regulation of anatomical structure morphogenesisGO:00226032420.013
rna processingGO:00063961470.013
response to external biotic stimulusGO:00432072930.013
dendrite developmentGO:00163582040.013
response to radiationGO:00093141550.013
limb developmentGO:006017310.013
response to hexoseGO:000974630.013
cell cycle phase transitionGO:00447701400.013
signal transduction by phosphorylationGO:00230141070.013
regulation of transcription from rna polymerase ii promoterGO:00063573780.013
regulation of hydrolase activityGO:0051336970.013
regulation of apoptotic processGO:00429811300.013
lateral inhibitionGO:00463312060.013
nitrogen compound transportGO:0071705850.013
regulation of i kappab kinase nf kappab signalingGO:004312220.013
signal releaseGO:0023061490.013
Fly
establishment or maintenance of cell polarityGO:00071631670.013
defense response to bacteriumGO:00427421780.013
response to alcoholGO:0097305950.013
mitotic cell cycle phase transitionGO:00447721380.013
centrosome cycleGO:00070981370.013
response to bacteriumGO:00096171980.013
camera type eye morphogenesisGO:004859320.013
negative regulation of cell cycleGO:00457861160.013
mitotic g2 dna damage checkpointGO:0007095690.012
positive regulation of apoptotic signaling pathwayGO:200123540.012
response to biotic stimulusGO:00096072940.012
multi organism behaviorGO:00517051750.012
metal ion transportGO:0030001740.012
humoral immune responseGO:00069591170.012
carbohydrate derivative biosynthetic processGO:1901137850.012
positive regulation of rna metabolic processGO:00512542710.012
segmentationGO:00352822070.012
regulation of cellular response to stressGO:0080135890.012
response to monosaccharideGO:003428440.012
embryonic development via the syncytial blastodermGO:00017001480.012
regulation of epithelial cell proliferationGO:005067840.012
dna integrity checkpointGO:0031570810.012
mitotic dna damage checkpointGO:0044773740.012
anatomical structure homeostasisGO:0060249970.012
l glutamate importGO:005193810.012
single organism intracellular transportGO:19025822070.012
guanosine containing compound catabolic processGO:1901069740.012
lipid metabolic processGO:00066291210.012
negative regulation of rna biosynthetic processGO:19026792400.012
posttranscriptional regulation of gene expressionGO:00106081450.012
columnar cuboidal epithelial cell differentiationGO:00020652560.012
positive regulation of cellular catabolic processGO:0031331950.012
regulation of nervous system developmentGO:00519602480.012
regulation of wnt signaling pathwayGO:0030111680.012
cellular macromolecular complex assemblyGO:00346221530.012
embryonic pattern specificationGO:00098801740.012
estrogen metabolic processGO:000821010.012
tissue deathGO:00162711020.012
retina development in camera type eyeGO:006004140.012
epithelial cell developmentGO:00020642740.012
nephron epithelium developmentGO:007200930.012
cell recognitionGO:00080371020.012
immune response activating signal transductionGO:000275720.012
regulation of cytoskeleton organizationGO:0051493890.012
ethanolamine containing compound metabolic processGO:004243940.012
positive regulation of molecular functionGO:00440931360.012
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.012
regulation of phosphorylationGO:00423251470.012
head developmentGO:00603221350.012
response to ethanolGO:0045471590.012
multicellular organismal reproductive behaviorGO:00330571100.012
synapse organizationGO:00508081960.012
defense response to gram negative bacteriumGO:0050829940.012
regulation of cell developmentGO:00602842150.011
cellular response to biotic stimulusGO:007121640.011
positive regulation of transcription dna templatedGO:00458932660.011
kidney morphogenesisGO:006099330.011
neurotransmitter secretionGO:0007269350.011
Fly
regulation of developmental growthGO:00486381740.011
negative regulation of cell cycle phase transitionGO:19019881030.011
negative regulation of multicellular organismal processGO:00512411420.011
hindbrain developmentGO:003090220.011
mesenchymal cell differentiationGO:004876210.011
regulation of neurotransmitter levelsGO:0001505380.011
Fly
response to copper ionGO:004668840.011
salivary gland histolysisGO:0035070880.011
cellular response to molecule of bacterial originGO:007121930.011
enzyme linked receptor protein signaling pathwayGO:00071671790.011
cellular response to ethanolGO:007136140.011
actin cytoskeleton organizationGO:00300362060.011
cellular ketone metabolic processGO:0042180240.011
rna splicingGO:0008380830.011
vitamin biosynthetic processGO:000911010.011
regulation of synapse structure and activityGO:00508031280.011
dorsal ventral pattern formationGO:00099531330.011
meiotic nuclear divisionGO:00071261510.011
negative regulation of nucleic acid templated transcriptionGO:19035072400.011
nucleocytoplasmic transportGO:0006913720.011
regulation of mapk cascadeGO:0043408920.011
negative regulation of transcription dna templatedGO:00458922370.011
cellular protein catabolic processGO:0044257830.011
leg disc developmentGO:0035218920.011
cation transmembrane transportGO:0098655880.011
cytoskeleton dependent cytokinesisGO:0061640810.011
endomembrane system organizationGO:00102561190.011
meiotic cell cycleGO:00513211710.011
positive regulation of cellular component organizationGO:00511301560.011
chemosensory behaviorGO:00076351060.011
negative regulation of protein metabolic processGO:0051248850.011
actin filament organizationGO:00070151260.011
wing disc pattern formationGO:0035222660.011
brain developmentGO:00074201200.011
behavioral response to ethanolGO:0048149490.011
ovarian follicle cell developmentGO:00307072480.011
regulation of proteolysisGO:0030162870.011
negative regulation of mitotic cell cycleGO:00459301090.011
mushroom body developmentGO:0016319700.011
cellular metal ion homeostasisGO:0006875310.010
negative regulation of cell differentiationGO:00455961430.010
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.010
l amino acid importGO:004309220.010
nephron tubule developmentGO:007208030.010
metal ion homeostasisGO:0055065440.010
mitotic cytokinesisGO:0000281500.010
xenobiotic catabolic processGO:004217810.010
locomotory behaviorGO:00076261760.010
hematopoietic progenitor cell differentiationGO:000224410.010
vitamin metabolic processGO:000676620.010
apoptotic processGO:00069151590.010
spermatogenesisGO:00072832000.010
response to light stimulusGO:00094161240.010
axis specificationGO:00097981670.010
nuclear transportGO:0051169720.010
negative regulation of mitotic cell cycle phase transitionGO:19019911030.010
limb morphogenesisGO:003510810.010
sensory perception of chemical stimulusGO:00076061160.010
anterior posterior pattern specificationGO:00099521360.010
negative regulation of cellular component organizationGO:00511291080.010
detection of stimulusGO:00516061560.010
cytokinesisGO:0000910900.010
autophagic cell deathGO:0048102830.010
imaginal disc pattern formationGO:0007447910.010
regulation of cellular localizationGO:00603411360.010
neurotransmitter metabolic processGO:004213320.010

mthl3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.034
nervous system diseaseDOID:86300.020
cardiovascular system diseaseDOID:128700.018
disease of metabolismDOID:001466700.016
inherited metabolic disorderDOID:65500.016
musculoskeletal system diseaseDOID:1700.014
disease of cellular proliferationDOID:1456600.012
cancerDOID:16200.011
sensory system diseaseDOID:005015500.011
organ system cancerDOID:005068600.011
eye and adnexa diseaseDOID:149200.011
urinary system diseaseDOID:1800.010