Drosophila melanogaster

70 known processes

wgn (Dmel_CG6531)

wengen

(Aliases: vader,Dmel\CG6531,CG6531)

wgn biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
axon guidanceGO:00074112330.460
taxisGO:00423303040.435
photoreceptor cell axon guidanceGO:0072499230.422
axon developmentGO:00615642970.397
ion transmembrane transportGO:00342201220.376
neuron projection guidanceGO:00974852410.373
axonogenesisGO:00074092900.355
chemotaxisGO:00069352490.231
appendage morphogenesisGO:00351073970.212
eye morphogenesisGO:00485922600.191
respiratory system developmentGO:00605412130.186
regulation of cell differentiationGO:00455953020.184
open tracheal system developmentGO:00074242040.176
ion transportGO:00068111450.150
positive regulation of cellular biosynthetic processGO:00313283160.136
chromosome organizationGO:00512763600.123
cell divisionGO:00513012480.120
intracellular signal transductionGO:00355563000.118
tube morphogenesisGO:00352391910.094
regulation of cell proliferationGO:00421271630.094
embryonic development via the syncytial blastodermGO:00017001480.092
imaginal disc derived appendage developmentGO:00487373990.091
g protein coupled receptor signaling pathwayGO:00071861360.090
negative regulation of developmental processGO:00510932010.088
tube developmentGO:00352952440.087
anion transportGO:0006820410.082
synapse assemblyGO:00074161430.077
gland morphogenesisGO:00226121450.077
imaginal disc derived appendage morphogenesisGO:00351143950.075
detection of stimulusGO:00516061560.073
cation transmembrane transportGO:0098655880.073
appendage developmentGO:00487364010.067
lateral inhibitionGO:00463312060.066
negative regulation of cell communicationGO:00106482230.066
post embryonic appendage morphogenesisGO:00351203850.066
regulation of cellular ketone metabolic processGO:001056530.065
negative regulation of multicellular organismal processGO:00512411420.064
tissue morphogenesisGO:00487292970.064
exocrine system developmentGO:00352721620.064
positive regulation of nucleic acid templated transcriptionGO:19035082660.064
single organism intracellular transportGO:19025822070.063
inorganic ion transmembrane transportGO:0098660730.063
imaginal disc derived wing hair organizationGO:0035317450.063
monocarboxylic acid transportGO:001571830.063
organic substance transportGO:00717022570.062
intracellular transportGO:00469072280.062
cell deathGO:00082192790.061
positive regulation of transcription dna templatedGO:00458932660.060
endocytosisGO:00068973100.060
negative regulation of rna biosynthetic processGO:19026792400.059
regulation of immune system processGO:00026821760.059
negative regulation of response to stimulusGO:00485852580.059
cell projection assemblyGO:0030031940.057
chromatin modificationGO:00165681470.057
positive regulation of cell communicationGO:00106472500.056
wnt signaling pathwayGO:0016055980.056
salivary gland morphogenesisGO:00074351450.056
dendrite developmentGO:00163582040.055
regulation of cell deathGO:00109411730.054
developmental growthGO:00485892800.054
regulation of nervous system developmentGO:00519602480.052
response to hexoseGO:000974630.052
wing disc morphogenesisGO:00074723440.051
regulation of cellular component biogenesisGO:00440872010.050
positive regulation of cellular component organizationGO:00511301560.050
sister chromatid segregationGO:0000819920.050
response to abiotic stimulusGO:00096283410.049
cranial nerve developmentGO:002154510.049
dna conformation changeGO:00711031050.047
regulation of cell developmentGO:00602842150.046
regulation of synapse structure and activityGO:00508031280.046
mitotic nuclear divisionGO:00070672130.045
biological adhesionGO:00226101380.045
vesicle mediated transportGO:00161923810.045
response to bacteriumGO:00096171980.045
regulation of tube architecture open tracheal systemGO:0035152680.045
cell junction organizationGO:0034330570.044
embryonic morphogenesisGO:00485982060.044
compound eye morphogenesisGO:00017452490.044
negative regulation of nitrogen compound metabolic processGO:00511722650.044
single organism membrane organizationGO:0044802930.044
regulation of mitotic cell cycleGO:00073461900.043
negative regulation of gene expressionGO:00106293870.043
eye developmentGO:00016543230.043
mitotic cytokinesisGO:0000281500.043
organelle fissionGO:00482853400.043
response to glucoseGO:000974920.043
regulation of anatomical structure morphogenesisGO:00226032420.042
small molecule metabolic processGO:00442813050.041
cell junction assemblyGO:0034329420.041
carboxylic acid metabolic processGO:0019752920.041
immune system processGO:00023763470.040
regulation of ion transportGO:0043269390.039
positive regulation of macromolecule metabolic processGO:00106044050.039
salivary gland developmentGO:00074311620.039
organonitrogen compound metabolic processGO:19015643180.039
cellular protein modification processGO:00064644380.039
organic acid metabolic processGO:00060821030.039
gene silencingGO:00164581380.038
response to monosaccharideGO:003428440.038
chromatin organizationGO:00063252070.038
gland developmentGO:00487321910.038
neuron recognitionGO:00080381010.038
regulation of neuron projection developmentGO:0010975690.037
imaginal disc derived wing morphogenesisGO:00074763370.037
positive regulation of biosynthetic processGO:00098913160.037
neurological system processGO:00508773580.037
regulation of neuron differentiationGO:00456641030.036
gliogenesisGO:0042063800.036
transmembrane transportGO:00550851390.036
peptidyl amino acid modificationGO:00181931050.036
regulation of transportGO:00510491810.036
response to oxygen containing compoundGO:19017002000.035
regulation of synapse organizationGO:00508071100.035
membrane organizationGO:00610241120.035
regulation of proteolysisGO:0030162870.034
nuclear divisionGO:00002803320.034
developmental growth involved in morphogenesisGO:0060560650.034
organic substance catabolic processGO:19015753080.034
response to alcoholGO:0097305950.034
cellular catabolic processGO:00442483720.034
brain developmentGO:00074201200.034
defense response to other organismGO:00985422250.034
positive regulation of transportGO:0051050920.033
regulation of synaptic growth at neuromuscular junctionGO:0008582890.033
phagocytosisGO:00069092150.033
developmental maturationGO:00217001720.033
morphogenesis of an epitheliumGO:00020092760.033
negative regulation of cellular metabolic processGO:00313243820.033
negative regulation of cell differentiationGO:00455961430.032
epithelial tube morphogenesisGO:0060562880.032
positive regulation of macromolecule biosynthetic processGO:00105572830.032
monovalent inorganic cation transportGO:0015672400.032
forebrain developmentGO:003090020.031
motor neuron axon guidanceGO:0008045580.031
response to external biotic stimulusGO:00432072930.031
positive regulation of nucleobase containing compound metabolic processGO:00459353320.031
synaptic growth at neuromuscular junctionGO:00511241190.031
positive regulation of rna metabolic processGO:00512542710.031
cell cell signaling involved in cell fate commitmentGO:00451682100.031
oxoacid metabolic processGO:00434361030.031
regulation of cellular amine metabolic processGO:003323830.031
protein localizationGO:00081042840.031
branching involved in open tracheal system developmentGO:0060446450.031
epithelial cell differentiationGO:00308553220.031
neuromuscular junction developmentGO:00075281490.031
catabolic processGO:00090564090.031
positive regulation of response to stimulusGO:00485843230.030
cellular response to endogenous stimulusGO:0071495800.030
sensory organ morphogenesisGO:00905962600.030
cellular amino acid metabolic processGO:0006520610.030
cognitionGO:00508901410.030
protein acylationGO:0043543420.029
programmed cell deathGO:00125012570.029
regulation of molecular functionGO:00650092170.029
cytoskeleton dependent cytokinesisGO:0061640810.029
regulation of wnt signaling pathwayGO:0030111680.029
epithelial cell developmentGO:00020642740.029
cation transportGO:00068121100.029
positive regulation of gene expressionGO:00106282900.029
regulation of tube size open tracheal systemGO:0035151430.028
synaptic transmissionGO:00072682880.028
negative regulation of signalingGO:00230572190.028
columnar cuboidal epithelial cell developmentGO:00020662490.028
disaccharide metabolic processGO:000598440.027
compound eye developmentGO:00487493070.027
establishment of localization in cellGO:00516494020.027
response to drugGO:0042493170.027
dna metabolic processGO:00062592270.027
histone modificationGO:00165701060.027
transcription from rna polymerase ii promoterGO:00063663680.027
glial cell developmentGO:0021782270.026
kidney developmentGO:000182230.026
extrinsic apoptotic signaling pathwayGO:009719110.026
positive regulation of rna biosynthetic processGO:19026802660.026
organic acid transportGO:0015849180.026
response to organic substanceGO:00100332840.026
nf kappab import into nucleusGO:004234810.026
response to organic cyclic compoundGO:0014070890.025
limb morphogenesisGO:003510810.025
positive regulation of secretionGO:0051047220.025
positive regulation of catalytic activityGO:00430851180.025
regulation of transcription from rna polymerase ii promoterGO:00063573780.025
establishment or maintenance of cell polarityGO:00071631670.025
olfactory behaviorGO:0042048970.025
mitotic sister chromatid segregationGO:0000070870.024
rho protein signal transductionGO:0007266140.024
regulation of catalytic activityGO:00507901850.024
phosphorylationGO:00163102940.024
cell migrationGO:00164772380.024
localization of cellGO:00516742570.024
response to woundingGO:0009611940.023
homeostatic processGO:00425921990.023
ovarian follicle cell developmentGO:00307072480.023
single organism carbohydrate metabolic processGO:0044723720.023
cell maturationGO:00484691440.023
internal protein amino acid acetylationGO:0006475380.023
cellular response to dna damage stimulusGO:00069742230.023
positive regulation of signal transductionGO:00099672230.023
body morphogenesisGO:001017120.023
growthGO:00400073590.023
spindle organizationGO:00070512530.023
proteolysisGO:00065081920.023
cellular macromolecule catabolic processGO:00442651360.023
positive regulation of nitrogen compound metabolic processGO:00511733540.023
nitrogen compound transportGO:0071705850.023
regulation of hydrolase activityGO:0051336970.022
positive regulation of cell developmentGO:0010720610.022
response to oxidative stressGO:0006979860.022
cellular homeostasisGO:0019725800.022
defense response to bacteriumGO:00427421780.022
purine nucleotide metabolic processGO:00061631460.022
metal ion transportGO:0030001740.022
regulation of response to stressGO:00801342000.022
eye photoreceptor cell developmentGO:0042462810.022
multicellular organismal homeostasisGO:0048871410.022
morphogenesis of a branching epitheliumGO:0061138450.022
cellular carbohydrate metabolic processGO:0044262220.021
carboxylic acid transportGO:0046942180.021
cell adhesionGO:00071551360.021
cellular response to chemical stimulusGO:00708871990.021
stem cell maintenanceGO:0019827670.021
cellular ketone metabolic processGO:0042180240.021
negative regulation of signal transductionGO:00099682060.021
positive regulation of developmental processGO:00510941430.020
establishment of organelle localizationGO:00516561220.020
inorganic cation transmembrane transportGO:0098662610.020
defense responseGO:00069523000.020
cellular amine metabolic processGO:0044106120.020
regulation of secretionGO:0051046440.020
lipid metabolic processGO:00066291210.020
regulation of apoptotic processGO:00429811300.020
actomyosin structure organizationGO:0031032560.020
larval developmentGO:00021641040.020
stem cell differentiationGO:00488631170.020
negative regulation of synapse assemblyGO:0051964390.019
actin filament organizationGO:00070151260.019
ion homeostasisGO:0050801550.019
regulation of neurogenesisGO:00507671580.019
circulatory system developmentGO:0072359820.019
positive regulation of immune system processGO:0002684680.019
developmental programmed cell deathGO:00106231380.019
positive regulation of phosphorylationGO:0042327870.019
organophosphate metabolic processGO:00196371950.019
mitotic spindle organizationGO:00070522200.019
negative regulation of biosynthetic processGO:00098902770.019
muscle structure developmentGO:00610612240.019
nephron developmentGO:007200630.019
synapse organizationGO:00508081960.019
regulation of organelle organizationGO:00330431960.019
digestive system developmentGO:00551231490.019
carbohydrate metabolic processGO:0005975820.019
retinal cell programmed cell deathGO:0046666250.019
regulation of cellular protein metabolic processGO:00322682430.019
positive regulation of signalingGO:00230562430.019
cell proliferationGO:00082832990.019
morphogenesis of a branching structureGO:0001763450.019
cellular protein localizationGO:00346131600.019
positive regulation of rho gtpase activityGO:0032321190.018
camera type eye developmentGO:004301040.018
carbohydrate derivative metabolic processGO:19011352170.018
macromolecule catabolic processGO:00090571610.018
response to biotic stimulusGO:00096072940.018
chemical homeostasisGO:0048878920.018
cell cycle phase transitionGO:00447701400.018
positive regulation of cellular catabolic processGO:0031331950.018
response to lipopolysaccharideGO:003249640.018
cell motilityGO:00488702510.018
covalent chromatin modificationGO:00165691060.018
posttranscriptional regulation of gene expressionGO:00106081450.018
regulation of response to woundingGO:1903034190.018
regulation of growthGO:00400082330.018
leg disc developmentGO:0035218920.018
gastrulation with mouth forming firstGO:0001703360.017
regulation of body fluid levelsGO:0050878140.017
limb developmentGO:006017310.017
adult behaviorGO:00305341370.017
cytokinesisGO:0000910900.017
chromosome segregationGO:00070591570.017
positive regulation of organelle organizationGO:0010638650.017
hippo signalingGO:0035329200.017
positive regulation of lipid metabolic processGO:004583440.017
l amino acid importGO:004309220.017
response to light stimulusGO:00094161240.017
protein processingGO:0016485680.017
regulation of transferase activityGO:0051338580.017
digestive tract developmentGO:00485651490.017
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.017
kidney epithelium developmentGO:007207330.017
negative regulation of nucleic acid templated transcriptionGO:19035072400.016
regulation of endopeptidase activityGO:0052548360.016
rna localizationGO:00064031150.016
regulation of developmental growthGO:00486381740.016
morphogenesis of embryonic epitheliumGO:0016331940.016
ommochrome metabolic processGO:0046152190.016
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.016
regulation of localizationGO:00328792750.016
negative regulation of rna metabolic processGO:00512532510.016
regulation of cell projection organizationGO:0031344920.016
secretionGO:00469031090.016
single organism cellular localizationGO:19025801800.016
dna packagingGO:0006323910.016
organic anion transportGO:0015711280.016
reproductive structure developmentGO:0048608740.016
peptidyl lysine modificationGO:0018205570.016
positive regulation of cellular amine metabolic processGO:003324000.016
single organism catabolic processGO:00447122280.015
establishment of protein localizationGO:00451841630.015
regulation of phosphorus metabolic processGO:00511742100.015
positive regulation of developmental growthGO:0048639620.015
regulation of cell morphogenesisGO:00226041630.015
response to ketoneGO:1901654340.015
enzyme linked receptor protein signaling pathwayGO:00071671790.015
regulation of lipid transportGO:003236830.015
salivary gland histolysisGO:0035070880.015
positive regulation of cell motilityGO:200014730.015
feeding behaviorGO:0007631500.015
negative regulation of programmed cell deathGO:0043069720.015
regulation of cell morphogenesis involved in differentiationGO:0010769610.015
establishment of tissue polarityGO:0007164870.015
organophosphate biosynthetic processGO:0090407460.015
dorsal ventral pattern formationGO:00099531330.015
response to lipidGO:0033993380.015
cellular response to lipopolysaccharideGO:007122230.014
neuron projection extensionGO:1990138320.014
cell cell junction assemblyGO:0007043380.014
nucleocytoplasmic transportGO:0006913720.014
cytoplasmic transportGO:00164821300.014
salivary gland cell autophagic cell deathGO:0035071830.014
digestive tract morphogenesisGO:00485461270.014
compound eye photoreceptor developmentGO:0042051780.014
columnar cuboidal epithelial cell differentiationGO:00020652560.014
purine ribonucleotide metabolic processGO:00091501450.014
response to peptide hormoneGO:0043434290.014
renal system developmentGO:0072001720.014
regulation of intracellular signal transductionGO:19025312360.014
chemosensory behaviorGO:00076351060.014
regulation of cell substrate adhesionGO:001081020.014
positive regulation of protein transportGO:0051222370.014
negative regulation of protein metabolic processGO:0051248850.014
regulation of cell cycleGO:00517262910.014
nucleobase containing compound catabolic processGO:00346551650.014
negative regulation of cellular protein metabolic processGO:0032269850.014
deathGO:00162652840.014
nucleoside triphosphate metabolic processGO:00091411200.014
microtubule organizing center organizationGO:00310231680.014
myotube cell developmentGO:001490430.014
positive regulation of catabolic processGO:00098961050.014
cellular macromolecular complex assemblyGO:00346221530.014
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.014
protein modification processGO:00362114380.014
small gtpase mediated signal transductionGO:0007264880.014
defense response to gram negative bacteriumGO:0050829940.014
negative regulation of growthGO:0045926840.014
response to decreased oxygen levelsGO:0036293580.013
dendrite morphogenesisGO:00488131990.013
meiotic cell cycleGO:00513211710.013
urogenital system developmentGO:0001655720.013
ras protein signal transductionGO:0007265880.013
apoptotic processGO:00069151590.013
dorsal closureGO:0007391790.013
photoreceptor cell developmentGO:0042461960.013
regionalizationGO:00030024160.013
regulation of gene expression epigeneticGO:00400291280.013
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.013
response to endogenous stimulusGO:00097191190.013
detection of light stimulusGO:0009583580.013
negative regulation of cell cycle processGO:00109481090.013
cellular lipid metabolic processGO:0044255830.013
skeletal muscle fiber developmentGO:004874130.013
negative regulation of nervous system developmentGO:0051961920.013
response to hypoxiaGO:0001666530.013
determination of adult lifespanGO:00083401370.013
nuclear transportGO:0051169720.013
photoreceptor cell differentiationGO:00465301700.013
response to radiationGO:00093141550.013
cellular protein catabolic processGO:0044257830.013
camera type eye morphogenesisGO:004859320.013
positive regulation of cell migrationGO:003033520.013
head developmentGO:00603221350.013
cellular response to hormone stimulusGO:0032870440.013
regulation of catabolic processGO:00098941700.012
regulation of cell cycle processGO:00105641810.012
regulation of synapse assemblyGO:0051963940.012
regulation of cellular amino acid metabolic processGO:000652100.012
regulation of multi organism processGO:00439001310.012
regulation of protein metabolic processGO:00512462560.012
positive regulation of transcription factor import into nucleusGO:0042993190.012
organelle fusionGO:0048284460.012
regulation of lipid metabolic processGO:0019216150.012
nicotinamide nucleotide metabolic processGO:004649620.012
regulation of cellular response to stressGO:0080135890.012
purine nucleoside metabolic processGO:00422781270.012
cellular response to molecule of bacterial originGO:007121930.012
embryo development ending in birth or egg hatchingGO:00097921520.012
negative regulation of catalytic activityGO:0043086420.012
actin cytoskeleton organizationGO:00300362060.012
positive regulation of cellular amino acid metabolic processGO:004576400.012
immune response regulating signaling pathwayGO:000276420.012
stress activated protein kinase signaling cascadeGO:0031098550.012
response to nutrient levelsGO:00316671140.012
secretion by cellGO:00329401010.012
negative regulation of cell cycleGO:00457861160.012
necrotic cell deathGO:007026510.012
gastrulation involving germ band extensionGO:0010004360.012
canonical wnt signaling pathwayGO:0060070210.012
cellular nitrogen compound catabolic processGO:00442701650.012
establishment of glial blood brain barrierGO:0060857140.012
regulation of immune responseGO:00507761180.012
cardiovascular system developmentGO:0072358820.012
positive regulation of hydrolase activityGO:0051345780.012
response to oxygen levelsGO:0070482590.011
organic cyclic compound catabolic processGO:19013611680.011
establishment of planar polarityGO:0001736870.011
translationGO:0006412690.011
glial cell differentiationGO:0010001350.011
nucleotide metabolic processGO:00091171610.011
gastrulationGO:0007369700.011
cellular response to nitrogen compoundGO:1901699510.011
histolysisGO:00075591020.011
purine containing compound metabolic processGO:00725211550.011
agingGO:00075681430.011
wing disc pattern formationGO:0035222660.011
single organism behaviorGO:00447083910.011
negative regulation of molecular functionGO:0044092510.011
regulation of response to external stimulusGO:00321011150.011
positive regulation of apoptotic signaling pathwayGO:200123540.011
negative regulation of transcription dna templatedGO:00458922370.011
response to calcium ionGO:005159210.011
embryonic organ developmentGO:0048568500.011
regulation of programmed cell deathGO:00430671520.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.011
positive regulation of cellular component biogenesisGO:0044089800.011
cell recognitionGO:00080371020.011
regulation of protein localizationGO:0032880760.011
detection of external stimulusGO:0009581660.011
autophagic cell deathGO:0048102830.011
peptidyl lysine acetylationGO:0018394390.011
humoral immune responseGO:00069591170.011
regulation of secretion by cellGO:1903530390.011
regulation of mapk cascadeGO:0043408920.010
muscle organ developmentGO:00075171270.010
neuronal stem cell maintenanceGO:009715040.010
smoothened signaling pathwayGO:0007224490.010
heterocycle catabolic processGO:00467001660.010
establishment of spindle localizationGO:0051293220.010
protein acetylationGO:0006473390.010
regulation of multicellular organismal developmentGO:20000264140.010
response to other organismGO:00517072930.010
neuronal action potentialGO:0019228100.010
regulation of kinase activityGO:0043549530.010
signal transduction by phosphorylationGO:00230141070.010
histone acetylationGO:0016573380.010
locomotory behaviorGO:00076261760.010
positive regulation of nucleotide catabolic processGO:0030813460.010
response to nitrogen compoundGO:1901698900.010
multi multicellular organism processGO:00447061230.010
positive regulation of phosphorus metabolic processGO:00105621390.010
ribonucleotide catabolic processGO:00092611090.010

wgn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.118
nervous system diseaseDOID:86300.027
musculoskeletal system diseaseDOID:1700.021
connective tissue diseaseDOID:6500.015
bone diseaseDOID:008000100.015
cancerDOID:16200.015
disease of cellular proliferationDOID:1456600.015
organ system cancerDOID:005068600.014